==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=24-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER GUANINE NUCLEOTIDE EXCHANGE FACTOR 19-DEC-97 1A12 . COMPND 2 MOLECULE: REGULATOR OF CHROMOSOME CONDENSATION 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR L.RENAULT,N.NASSAR,I.VETTER,J.BECKER,M.ROTH,A.WITTINGHOFER . 1203 3 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 44330.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 713 59.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 421 35.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 5 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 18 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 27 2.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 3 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 83 6.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 117 9.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 13 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 11 7 13 2 34 7 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 3 18 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 21 A K 0 0 172 0, 0.0 2,-1.9 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 129.7 9.7 -11.3 33.7 2 22 A K - 0 0 164 1,-0.1 2,-0.2 0, 0.0 0, 0.0 -0.433 360.0-153.3 -64.1 85.0 10.1 -13.4 30.5 3 23 A V - 0 0 42 -2,-1.9 2,-0.2 114,-0.1 768,-0.1 -0.429 8.7-128.1 -66.5 129.9 11.5 -10.5 28.4 4 24 A K - 0 0 130 -2,-0.2 2,-0.3 765,-0.1 113,-0.3 -0.476 21.9-164.8 -79.9 149.3 10.9 -10.9 24.7 5 25 A V - 0 0 13 111,-2.8 2,-0.2 -2,-0.2 113,-0.2 -0.942 6.3-177.4-126.4 157.4 13.6 -10.6 22.1 6 26 A S - 0 0 20 719,-1.4 2,-0.3 -2,-0.3 720,-0.1 -0.694 8.2-153.8-133.2-164.5 13.4 -10.1 18.3 7 27 A H > - 0 0 2 -2,-0.2 3,-1.6 718,-0.1 721,-0.3 -0.944 32.3-112.1-169.7 155.9 15.9 -9.9 15.4 8 28 A R T 3 S+ 0 0 53 718,-0.4 720,-0.3 716,-0.3 717,-0.1 0.690 115.2 60.4 -69.3 -20.9 16.0 -8.3 12.0 9 29 A S T 3 S+ 0 0 34 146,-0.2 -1,-0.3 718,-0.1 2,-0.2 0.548 78.3 108.7 -77.8 -13.9 15.9 -11.8 10.5 10 30 A H < - 0 0 22 -3,-1.6 2,-0.3 145,-0.1 93,-0.1 -0.516 67.8-130.5 -73.7 135.3 12.6 -12.8 12.0 11 31 A S + 0 0 54 91,-0.4 39,-0.1 -2,-0.2 40,-0.1 -0.635 33.1 165.5 -89.6 139.6 9.7 -13.0 9.5 12 32 A T + 0 0 58 -2,-0.3 -1,-0.1 38,-0.1 39,-0.1 0.477 39.5 104.4-127.1 -10.7 6.4 -11.2 10.1 13 33 A E - 0 0 86 37,-0.3 2,-0.1 369,-0.1 36,-0.1 -0.712 65.9-128.8 -90.9 119.5 4.5 -11.1 6.8 14 34 A P + 0 0 47 0, 0.0 2,-0.2 0, 0.0 36,-0.2 -0.364 41.3 149.9 -66.9 139.2 1.6 -13.6 6.5 15 35 A G B -A 49 0A 4 34,-2.2 34,-2.1 -2,-0.1 2,-0.3 -0.802 42.5 -95.6-154.7-177.3 1.4 -15.8 3.5 16 36 A L E -E 395 0B 54 379,-2.8 379,-2.7 -2,-0.2 2,-0.4 -0.879 36.6-123.5-107.4 149.4 0.3 -19.0 1.8 17 37 A V E -EF 394 43B 1 26,-0.6 26,-2.8 -2,-0.3 2,-0.4 -0.802 24.3-176.3-100.0 131.6 2.7 -22.0 1.3 18 38 A L E -EF 393 42B 0 375,-2.7 375,-2.9 -2,-0.4 2,-0.3 -0.950 5.0-169.2-120.1 145.7 3.4 -23.6 -2.1 19 39 A T E +EF 392 41B 0 22,-2.3 22,-2.8 -2,-0.4 2,-0.3 -0.888 8.2 170.6-129.2 159.3 5.5 -26.7 -2.6 20 40 A L E +E 391 0B 0 371,-1.6 371,-2.4 -2,-0.3 2,-0.3 -0.968 38.7 49.1-160.4 163.5 7.0 -28.4 -5.7 21 41 A G E S-EF 390 37B 0 16,-3.0 16,-2.4 -2,-0.3 369,-0.3 -0.769 96.9 -4.2 103.0-151.2 9.5 -31.2 -6.6 22 42 A Q E + F 0 36B 26 367,-2.7 14,-0.2 -2,-0.3 367,-0.1 -0.570 47.9 176.2 -85.1 143.5 9.5 -34.7 -5.2 23 43 A G > + 0 0 1 12,-3.0 3,-1.5 -2,-0.2 13,-0.2 0.078 33.0 129.6-135.9 30.6 7.0 -35.8 -2.4 24 44 A D T 3 S+ 0 0 80 11,-0.4 -1,-0.1 1,-0.3 12,-0.1 0.733 83.8 35.0 -53.6 -40.0 7.7 -39.5 -1.9 25 45 A V T 3 S- 0 0 46 10,-0.1 -1,-0.3 -3,-0.1 49,-0.1 0.239 127.3 -88.2-110.7 17.0 8.1 -39.2 1.9 26 46 A G S X S+ 0 0 2 -3,-1.5 3,-1.3 8,-0.1 5,-0.2 0.367 85.5 130.1 99.9 3.1 5.5 -36.4 2.5 27 47 A Q T 3 S+ 0 0 0 1,-0.3 -4,-0.1 30,-0.2 31,-0.1 0.635 71.1 57.3 -66.8 -17.5 7.6 -33.3 2.0 28 48 A L T 3 S- 0 0 2 6,-0.2 -1,-0.3 -5,-0.2 -5,-0.1 0.739 96.3-143.0 -80.2 -23.0 5.2 -31.7 -0.4 29 49 A G < + 0 0 6 -3,-1.3 15,-0.2 -6,-0.1 -2,-0.1 0.690 64.5 119.8 69.0 26.8 2.5 -32.0 2.2 30 50 A L S S- 0 0 38 1,-0.3 3,-0.3 4,-0.3 4,-0.3 0.047 76.1 -99.3-111.0 21.4 -0.2 -32.8 -0.3 31 51 A G > - 0 0 14 59,-2.9 3,-0.6 -5,-0.2 -1,-0.3 -0.138 50.3 -54.1 91.9 179.9 -1.3 -36.2 1.0 32 52 A E T 3 S+ 0 0 126 1,-0.2 -1,-0.2 -3,-0.1 59,-0.0 0.635 127.5 52.9 -72.6 -16.6 -0.6 -39.8 0.1 33 53 A N T 3 S+ 0 0 157 -3,-0.3 2,-0.9 1,-0.1 -1,-0.2 0.630 89.7 78.0 -97.6 -17.0 -1.5 -39.5 -3.6 34 54 A V < + 0 0 24 -3,-0.6 -4,-0.3 -4,-0.3 -6,-0.2 -0.786 44.7 157.5-102.8 96.5 0.7 -36.6 -4.6 35 55 A M + 0 0 67 -2,-0.9 -12,-3.0 1,-0.2 -11,-0.4 0.540 66.3 20.6 -94.7 -13.2 4.2 -37.9 -5.1 36 56 A E E -F 22 0B 71 -14,-0.2 2,-0.4 -13,-0.2 -1,-0.2 -0.970 53.4-167.7-159.1 138.3 5.4 -35.1 -7.5 37 57 A R E -F 21 0B 96 -16,-2.4 -16,-3.0 -2,-0.3 321,-0.1 -0.969 3.8-169.7-130.9 118.9 4.6 -31.6 -8.5 38 58 A K E S+ 0 0 95 -2,-0.4 322,-0.8 -18,-0.2 320,-0.2 0.698 80.4 31.5 -80.1 -20.3 6.2 -30.0 -11.6 39 59 A K E S- 0 0 103 320,-0.1 -20,-0.1 321,-0.1 -18,-0.1 -0.929 109.1 -71.9-132.6 156.5 4.9 -26.6 -10.7 40 60 A P E - 0 0 9 0, 0.0 335,-0.4 0, 0.0 2,-0.4 -0.174 50.2-163.4 -53.2 133.4 4.2 -24.9 -7.4 41 61 A A E -F 19 0B 11 -22,-2.8 -22,-2.3 -4,-0.1 2,-0.2 -0.976 21.6-110.8-123.7 142.1 1.1 -26.3 -5.6 42 62 A L E -F 18 0B 68 -2,-0.4 2,-0.6 -24,-0.2 -24,-0.2 -0.384 24.8-155.9 -74.9 127.1 -0.9 -24.8 -2.7 43 63 A V E -F 17 0B 3 -26,-2.8 -26,-0.6 -2,-0.2 2,-0.4 -0.944 19.1-127.3-102.9 121.4 -0.6 -26.6 0.6 44 64 A S + 0 0 103 -2,-0.6 -28,-0.0 -15,-0.2 -26,-0.0 -0.528 31.3 177.1 -71.8 120.1 -3.5 -26.0 3.0 45 65 A I - 0 0 29 -2,-0.4 4,-0.1 2,-0.1 -28,-0.0 -0.981 35.2-128.0-118.5 139.5 -2.4 -24.8 6.4 46 66 A P S S+ 0 0 101 0, 0.0 2,-0.3 0, 0.0 -1,-0.0 0.625 90.5 30.1 -57.6 -23.7 -5.0 -23.9 9.0 47 67 A E S S- 0 0 51 20,-0.0 2,-0.1 17,-0.0 -2,-0.1 -0.929 96.9 -83.4-129.7 168.3 -3.4 -20.5 9.6 48 68 A D - 0 0 87 -2,-0.3 16,-2.4 -32,-0.1 2,-0.4 -0.432 47.2-137.3 -67.8 147.6 -1.4 -17.8 7.8 49 69 A V E -AB 15 63A 1 -34,-2.1 -34,-2.2 14,-0.3 14,-0.3 -0.853 24.1-177.0-116.2 135.0 2.4 -18.6 7.7 50 70 A V E S+ 0 0 10 12,-2.8 2,-0.4 -2,-0.4 -37,-0.3 0.602 77.3 26.2-101.1 -21.0 5.2 -16.2 8.2 51 71 A Q E - B 0 62A 14 11,-1.3 11,-3.0 -39,-0.1 2,-0.4 -0.986 59.6-173.5-146.2 130.5 8.2 -18.6 7.6 52 72 A A E - B 0 61A 1 -2,-0.4 2,-0.4 9,-0.2 9,-0.2 -0.973 12.3-173.9-128.4 118.3 8.4 -21.7 5.5 53 73 A E E - B 0 60A 52 7,-3.1 7,-2.6 -2,-0.4 2,-0.5 -0.936 17.6-142.7-116.7 141.1 11.5 -23.9 5.6 54 74 A A E - B 0 59A 8 -2,-0.4 332,-0.3 5,-0.2 5,-0.2 -0.777 16.0-168.9 -99.2 122.1 12.6 -26.9 3.6 55 75 A G - 0 0 3 3,-3.1 333,-0.4 -2,-0.5 53,-0.3 -0.354 49.9 -79.8 -81.8-164.6 14.6 -29.6 5.5 56 76 A G S S- 0 0 7 51,-2.1 332,-2.1 1,-0.2 333,-0.7 0.922 121.3 -8.7 -64.1 -50.0 16.3 -32.4 3.6 57 77 A M S S+ 0 0 54 51,-0.4 16,-2.3 50,-0.3 2,-0.3 -0.082 129.9 63.8-142.9 28.9 13.1 -34.4 3.1 58 78 A H E - C 0 72A 2 14,-0.3 -3,-3.1 49,-0.2 2,-0.4 -0.932 64.5-137.2-147.8 170.8 10.7 -32.5 5.4 59 79 A T E -BC 54 71A 0 12,-2.6 12,-1.8 -2,-0.3 2,-0.4 -0.989 8.8-163.0-139.6 136.4 9.0 -29.0 5.6 60 80 A V E -BC 53 70A 0 -7,-2.6 -7,-3.1 -2,-0.4 2,-0.5 -0.990 5.8-169.4-127.5 123.7 8.4 -26.8 8.6 61 81 A C E -BC 52 69A 0 8,-3.1 8,-2.8 -2,-0.4 2,-0.6 -0.956 9.7-151.6-119.2 127.0 6.0 -23.9 8.5 62 82 A L E -BC 51 68A 1 -11,-3.0 -12,-2.8 -2,-0.5 -11,-1.3 -0.867 17.7-140.1-100.6 121.1 5.7 -21.2 11.3 63 83 A S E > -B 49 0A 1 4,-3.7 3,-2.0 -2,-0.6 -14,-0.3 -0.432 22.3-114.1 -74.2 160.4 2.3 -19.6 11.7 64 84 A K T 3 S+ 0 0 107 -16,-2.4 -15,-0.1 1,-0.3 -1,-0.1 0.780 118.9 56.7 -57.3 -33.1 1.7 -16.0 12.4 65 85 A S T 3 S- 0 0 59 -17,-0.4 -1,-0.3 2,-0.1 -16,-0.1 0.499 125.8-100.2 -82.1 -3.1 0.4 -17.0 15.8 66 86 A G S < S+ 0 0 2 -3,-2.0 35,-1.9 1,-0.3 2,-0.3 0.611 77.7 134.5 98.4 12.5 3.6 -18.8 16.7 67 87 A Q - 0 0 64 33,-0.1 -4,-3.7 31,-0.1 2,-0.5 -0.734 46.6-135.5 -98.3 150.2 2.6 -22.4 15.9 68 88 A V E -C 62 0A 4 27,-0.4 27,-3.1 -2,-0.3 2,-0.4 -0.884 16.4-173.1-107.5 128.5 4.7 -24.9 14.0 69 89 A Y E -CD 61 94A 15 -8,-2.8 -8,-3.1 -2,-0.5 2,-0.3 -0.939 11.0-176.3-115.7 140.6 3.3 -27.2 11.3 70 90 A S E +CD 60 93A 0 23,-2.4 23,-1.4 -2,-0.4 2,-0.3 -0.957 11.2 174.3-138.3 155.6 5.5 -30.0 9.8 71 91 A F E +C 59 0A 0 -12,-1.8 -12,-2.6 -2,-0.3 2,-0.3 -0.973 39.2 56.2-160.5 143.9 5.3 -32.6 7.0 72 92 A G E S+C 58 0A 0 17,-2.6 2,-0.3 -2,-0.3 -14,-0.3 -0.886 88.3 3.7 132.0-163.4 7.7 -35.1 5.5 73 93 A C + 0 0 38 -16,-2.3 3,-0.2 -2,-0.3 5,-0.2 -0.464 48.3 174.8 -67.5 122.7 9.9 -37.9 6.7 74 94 A N > + 0 0 10 -2,-0.3 3,-0.9 4,-0.1 -1,-0.1 0.134 42.8 114.7-117.4 25.0 9.6 -38.6 10.4 75 95 A D T 3 S+ 0 0 120 1,-0.3 -1,-0.1 2,-0.1 34,-0.1 0.778 91.2 32.9 -63.6 -32.0 11.9 -41.7 10.7 76 96 A E T 3 S- 0 0 34 -3,-0.2 66,-0.4 49,-0.1 -1,-0.3 0.309 122.0-100.2-106.5 2.1 14.3 -39.7 12.9 77 97 A G S X S+ 0 0 0 -3,-0.9 3,-2.1 47,-0.1 47,-0.1 0.421 74.6 141.2 90.9 14.8 11.7 -37.4 14.6 78 98 A A T 3 + 0 0 2 1,-0.3 -4,-0.1 -5,-0.2 45,-0.1 0.748 67.3 60.0 -61.1 -26.9 12.2 -34.3 12.4 79 99 A L T 3 S- 0 0 0 2,-0.2 -1,-0.3 -6,-0.1 3,-0.1 0.725 94.0-142.9 -76.1 -20.9 8.5 -33.6 12.3 80 100 A G < + 0 0 3 -3,-2.1 16,-0.5 1,-0.2 2,-0.3 0.791 68.5 84.5 66.5 29.6 8.3 -33.2 16.1 81 101 A R S S- 0 0 31 14,-0.2 2,-0.5 63,-0.1 -1,-0.2 -0.970 89.0 -86.6-161.6 157.2 4.9 -34.8 16.3 82 102 A D + 0 0 128 -2,-0.3 3,-0.2 1,-0.1 62,-0.0 -0.623 36.9 172.0 -80.9 115.7 3.4 -38.3 16.4 83 103 A T + 0 0 30 -2,-0.5 6,-0.2 1,-0.1 5,-0.2 -0.128 35.4 126.0-115.3 37.7 2.9 -39.9 12.9 84 104 A S + 0 0 96 4,-0.1 2,-0.3 2,-0.1 -1,-0.1 0.876 54.3 86.6 -59.4 -41.1 1.9 -43.3 14.1 85 105 A V S > S- 0 0 108 -3,-0.2 3,-2.3 1,-0.1 4,-0.3 -0.491 98.3-103.4 -62.9 123.6 -1.3 -43.1 12.0 86 106 A E T 3 S+ 0 0 168 -2,-0.3 -1,-0.1 1,-0.3 -2,-0.1 -0.224 102.4 7.4 -50.6 128.0 -0.5 -44.2 8.5 87 107 A G T > S+ 0 0 9 -4,-0.2 3,-2.0 -3,-0.1 -1,-0.3 0.319 89.0 120.2 83.0 -7.6 -0.2 -41.2 6.1 88 108 A S G X S+ 0 0 24 -3,-2.3 3,-0.6 1,-0.3 -2,-0.1 0.715 71.2 58.4 -65.6 -16.0 -0.3 -38.6 8.8 89 109 A E G 3 S+ 0 0 45 -4,-0.3 -17,-2.6 -6,-0.2 -1,-0.3 0.512 91.1 71.7 -88.0 -7.2 3.2 -37.3 7.8 90 110 A M G < S+ 0 0 12 -3,-2.0 -59,-2.9 -19,-0.2 -1,-0.2 0.405 99.8 44.7 -88.4 -4.9 2.0 -36.6 4.3 91 111 A V S < S- 0 0 67 -3,-0.6 -19,-0.2 -61,-0.2 -61,-0.1 -0.940 104.2 -78.1-133.5 157.4 -0.1 -33.6 5.3 92 112 A P + 0 0 29 0, 0.0 2,-0.3 0, 0.0 -21,-0.2 -0.268 51.0 179.4 -53.9 137.6 0.6 -30.6 7.6 93 113 A G E -D 70 0A 13 -23,-1.4 -23,-2.4 -4,-0.1 2,-0.3 -0.974 28.5-106.3-138.6 155.7 0.3 -31.5 11.3 94 114 A K E -D 69 0A 78 -2,-0.3 2,-0.4 -25,-0.2 -25,-0.2 -0.604 20.9-133.5 -88.0 137.8 0.8 -29.3 14.4 95 115 A V - 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