==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=8-JAN-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 18-OCT-11 4A4O . COMPND 2 MOLECULE: SERINE/THREONINE-PROTEIN KINASE PLK1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR J.A.BERTRAND,R.T.BOSSI . 290 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15105.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 183 63.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 44 15.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 14 4.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 37 12.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 76 26.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 3 0 0 0 1 1 1 0 0 0 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 1 2 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 39 A E 0 0 197 0, 0.0 85,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 43.3 23.1 46.3 25.3 2 40 A I - 0 0 40 1,-0.1 4,-0.0 45,-0.0 43,-0.0 -0.851 360.0-105.6-114.1 130.9 22.2 43.4 23.0 3 41 A P - 0 0 51 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 -0.042 17.1-133.7 -56.9 144.6 24.4 40.3 22.2 4 42 A E S S+ 0 0 140 12,-0.1 13,-1.0 2,-0.0 2,-0.2 0.986 94.8 36.2 -60.1 -58.1 26.2 40.1 18.9 5 43 A V E S-A 16 0A 60 11,-0.2 2,-0.4 27,-0.0 11,-0.2 -0.560 77.4-147.0 -90.1 160.1 25.1 36.5 18.4 6 44 A L E -A 15 0A 6 9,-1.3 9,-2.5 -2,-0.2 2,-0.4 -0.995 12.7-160.5-128.5 125.3 21.7 35.1 19.5 7 45 A V E -A 14 0A 68 -2,-0.4 7,-0.2 7,-0.3 6,-0.1 -0.898 14.6-156.3-113.5 135.7 21.4 31.6 20.7 8 46 A D > - 0 0 16 5,-2.8 4,-2.6 -2,-0.4 3,-0.4 -0.834 10.0-167.6-102.6 92.1 18.3 29.4 20.9 9 47 A P T 4 S+ 0 0 111 0, 0.0 -1,-0.1 0, 0.0 5,-0.1 0.603 84.6 43.3 -57.4 -9.9 19.3 26.9 23.6 10 48 A R T 4 S+ 0 0 229 3,-0.1 72,-0.0 -3,-0.0 -2,-0.0 0.743 124.7 28.2-109.8 -32.3 16.2 24.7 22.7 11 49 A S T 4 S- 0 0 31 -3,-0.4 2,-0.5 2,-0.2 -3,-0.0 0.424 103.1-141.4-104.2 -11.4 16.1 24.7 18.9 12 50 A R < + 0 0 211 -4,-2.6 -4,-0.0 1,-0.2 0, 0.0 -0.042 55.0 121.2 86.9 -25.6 19.9 25.1 19.1 13 51 A R - 0 0 107 -2,-0.5 -5,-2.8 -6,-0.1 2,-0.3 -0.209 46.1-148.3 -69.1 160.4 20.6 27.5 16.3 14 52 A R E -A 7 0A 145 20,-0.5 2,-0.5 -7,-0.2 -7,-0.3 -0.865 5.7-138.1-125.9 163.4 22.3 30.9 16.8 15 53 A Y E -A 6 0A 6 -9,-2.5 -9,-1.3 -2,-0.3 2,-0.3 -0.975 8.4-136.5-133.0 124.6 21.9 34.2 14.9 16 54 A V E -AB 5 33A 72 17,-2.6 17,-2.0 -2,-0.5 2,-0.8 -0.606 37.1-118.3 -71.7 138.1 24.4 36.7 13.8 17 55 A R E - B 0 32A 59 -13,-1.0 15,-0.3 -2,-0.3 -1,-0.1 -0.718 37.4-172.1 -94.0 109.0 23.0 40.1 14.5 18 56 A G E - 0 0 25 13,-2.2 14,-0.1 -2,-0.8 2,-0.1 0.416 31.6 -42.0 -82.6-146.7 22.4 42.3 11.4 19 57 A R E - 0 0 135 1,-0.1 12,-2.1 11,-0.1 -1,-0.2 -0.389 60.4 -93.9 -87.9 158.6 21.4 45.9 10.8 20 58 A F E + B 0 30A 93 10,-0.2 10,-0.2 1,-0.1 -1,-0.1 -0.279 42.5 167.3 -62.5 152.8 18.8 48.0 12.4 21 59 A L E - 0 0 73 8,-2.3 2,-0.3 1,-0.4 9,-0.2 0.516 51.0 -46.4-128.7 -60.8 15.4 48.1 10.7 22 60 A G E - B 0 29A 27 7,-1.0 7,-2.1 2,-0.0 -1,-0.4 -0.876 42.4-136.1-162.6-174.2 12.7 49.7 12.8 23 61 A K E + B 0 28A 159 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.970 12.7 178.4-162.9 152.1 11.1 49.8 16.2 24 62 A G E > - B 0 27A 30 3,-1.7 3,-0.8 -2,-0.3 2,-0.1 -0.820 61.5 -27.2-164.3 115.9 7.7 49.9 17.7 25 63 A G T 3 S- 0 0 72 -2,-0.3 -1,-0.2 1,-0.2 0, 0.0 -0.376 126.8 -19.6 66.6-158.5 6.8 49.9 21.4 26 64 A F T 3 S+ 0 0 55 -3,-0.1 2,-0.4 24,-0.1 -1,-0.2 0.411 122.6 98.1 -57.7 4.4 9.3 48.4 23.8 27 65 A A E < -B 24 0A 2 -3,-0.8 -3,-1.7 19,-0.2 2,-0.3 -0.787 49.5-175.6-102.5 138.6 10.6 46.6 20.7 28 66 A K E -BC 23 45A 115 17,-1.3 17,-2.6 -2,-0.4 2,-0.4 -0.883 20.7-146.5-118.7 161.9 13.6 47.4 18.4 29 67 A C E +BC 22 44A 22 -7,-2.1 -8,-2.3 -2,-0.3 -7,-1.0 -0.986 20.2 169.1-144.7 133.5 14.2 45.3 15.3 30 68 A F E -BC 20 43A 22 13,-2.0 13,-4.6 -2,-0.4 -10,-0.2 -0.920 34.8-108.8-137.1 158.5 17.1 44.0 13.3 31 69 A E E - C 0 42A 32 -12,-2.1 -13,-2.2 -2,-0.3 2,-0.3 -0.555 38.6-175.2 -84.7 162.9 17.9 41.6 10.6 32 70 A I E -BC 17 41A 1 9,-2.2 9,-2.9 -15,-0.3 2,-0.4 -0.979 18.5-133.3-164.6 140.4 19.9 38.5 11.6 33 71 A S E -BC 16 40A 37 -17,-2.0 -17,-2.6 -2,-0.3 7,-0.3 -0.897 21.3-126.5-116.1 134.4 21.4 35.5 9.8 34 72 A D - 0 0 14 5,-3.8 -20,-0.5 -2,-0.4 2,-0.5 0.626 35.6-148.0 -54.9 -13.6 21.1 31.9 10.8 35 73 A A S S+ 0 0 33 4,-0.3 -1,-0.2 1,-0.2 -20,-0.1 0.216 85.3 42.0 69.8 -19.6 24.9 31.8 10.8 36 74 A D S S+ 0 0 132 -2,-0.5 -1,-0.2 -22,-0.2 -2,-0.1 0.671 126.8 26.2-118.0 -62.4 24.9 28.2 9.7 37 75 A T S S- 0 0 92 -3,-0.3 -2,-0.1 2,-0.1 -3,-0.1 0.434 105.1-142.1 -76.2 -3.4 22.1 27.7 7.1 38 76 A K + 0 0 140 1,-0.2 -3,-0.1 -5,-0.1 -1,-0.0 0.454 42.7 157.7 67.6 1.4 23.1 31.3 6.8 39 77 A E - 0 0 107 -6,-0.2 -5,-3.8 1,-0.1 2,-0.4 -0.121 36.8-120.5 -65.0 158.9 19.5 32.3 6.2 40 78 A V E +C 33 0A 60 -7,-0.3 54,-0.5 -6,-0.1 2,-0.3 -0.833 35.2 159.4-113.0 136.0 18.2 35.8 6.8 41 79 A F E -C 32 0A 11 -9,-2.9 -9,-2.2 -2,-0.4 2,-0.5 -0.903 40.0-111.8-139.2 167.0 15.4 37.0 9.2 42 80 A A E -CD 31 92A 8 50,-2.3 50,-3.6 -2,-0.3 2,-0.6 -0.914 33.4-154.8 -96.8 134.1 14.1 40.0 11.0 43 81 A G E -CD 30 91A 3 -13,-4.6 -13,-2.0 -2,-0.5 2,-0.5 -0.940 5.5-151.8-114.3 119.2 14.5 39.7 14.7 44 82 A K E -CD 29 90A 22 46,-2.1 46,-2.6 -2,-0.6 2,-0.5 -0.769 19.7-167.5 -88.7 129.6 12.3 41.5 17.1 45 83 A I E -CD 28 89A 7 -17,-2.6 -17,-1.3 -2,-0.5 44,-0.2 -0.921 9.0-175.0-132.7 105.7 14.2 42.1 20.3 46 84 A V E - D 0 88A 2 42,-2.1 42,-3.3 -2,-0.5 2,-0.3 -0.869 23.2-129.6-110.3 128.4 12.6 43.3 23.6 47 85 A P E > - D 0 87A 26 0, 0.0 3,-1.4 0, 0.0 40,-0.3 -0.537 10.7-139.7 -71.3 131.8 14.6 44.2 26.7 48 86 A K G > S+ 0 0 25 38,-3.1 3,-0.6 -2,-0.3 39,-0.2 0.583 98.4 75.3 -69.5 -6.1 13.3 42.5 29.9 49 87 A S G > S+ 0 0 73 37,-0.6 3,-0.7 1,-0.2 -1,-0.3 0.819 94.5 48.8 -70.1 -31.7 13.9 45.8 31.6 50 88 A L G < S+ 0 0 89 -3,-1.4 -1,-0.2 1,-0.2 3,-0.2 0.491 107.9 58.8 -82.4 -3.5 10.8 47.2 30.0 51 89 A L G < + 0 0 3 -3,-0.6 -1,-0.2 -4,-0.2 6,-0.2 0.042 62.3 120.5-117.8 24.3 8.9 44.1 31.0 52 90 A L < + 0 0 136 -3,-0.7 -1,-0.1 4,-0.1 -2,-0.1 0.651 63.2 74.9 -64.4 -18.5 9.4 44.3 34.8 53 91 A K S > S- 0 0 116 -3,-0.2 4,-2.1 1,-0.1 5,-0.1 -0.711 82.0-132.3-100.3 144.8 5.7 44.4 35.4 54 92 A P H > S+ 0 0 91 0, 0.0 4,-2.7 0, 0.0 5,-0.2 0.863 106.1 58.0 -63.6 -32.5 3.4 41.4 35.0 55 93 A H H > S+ 0 0 98 2,-0.2 4,-1.7 1,-0.2 5,-0.1 0.900 108.8 44.1 -65.2 -41.1 1.0 43.4 32.8 56 94 A Q H > S+ 0 0 30 2,-0.2 4,-1.7 1,-0.2 -1,-0.2 0.911 112.7 54.3 -65.0 -44.4 3.7 44.2 30.2 57 95 A R H X S+ 0 0 109 -4,-2.1 4,-2.1 -6,-0.2 3,-0.5 0.952 107.6 47.7 -57.0 -52.6 4.9 40.7 30.4 58 96 A E H X S+ 0 0 115 -4,-2.7 4,-3.5 1,-0.2 5,-0.3 0.919 107.1 56.8 -54.7 -47.6 1.5 39.1 29.6 59 97 A K H X S+ 0 0 66 -4,-1.7 4,-1.4 1,-0.2 -1,-0.2 0.871 109.8 47.3 -49.4 -40.7 0.9 41.5 26.7 60 98 A M H X S+ 0 0 11 -4,-1.7 4,-1.2 -3,-0.5 -1,-0.2 0.854 112.7 46.5 -74.7 -38.9 4.2 40.2 25.2 61 99 A S H >X S+ 0 0 73 -4,-2.1 4,-3.3 2,-0.2 3,-0.7 0.935 108.1 56.6 -67.2 -47.4 3.4 36.6 25.7 62 100 A M H 3X S+ 0 0 68 -4,-3.5 4,-2.6 1,-0.3 5,-0.2 0.882 105.1 53.1 -51.1 -40.2 -0.1 37.0 24.3 63 101 A E H 3X S+ 0 0 18 -4,-1.4 4,-2.6 -5,-0.3 -1,-0.3 0.851 110.8 45.2 -67.8 -35.0 1.5 38.4 21.2 64 102 A I H < S+ 0 0 1 -4,-2.6 3,-1.0 -5,-0.2 -2,-0.2 0.968 120.6 44.1 -77.1 -52.9 -1.3 34.8 18.8 67 105 A H H >< S+ 0 0 7 -4,-2.6 3,-1.7 1,-0.3 11,-0.3 0.874 108.4 57.4 -62.5 -39.0 1.4 35.4 16.2 68 106 A R H 3< S+ 0 0 134 -4,-2.4 -1,-0.3 1,-0.3 -2,-0.2 0.735 98.9 60.7 -68.2 -21.3 3.0 32.0 16.6 69 107 A S T << S+ 0 0 63 -3,-1.0 2,-0.5 -4,-0.5 -1,-0.3 0.297 91.6 97.7 -83.2 10.8 -0.2 30.3 15.7 70 108 A L < + 0 0 8 -3,-1.7 8,-0.7 6,-0.1 2,-0.4 -0.883 37.6 161.0-120.3 128.1 -0.3 31.9 12.3 71 109 A A + 0 0 75 -2,-0.5 2,-0.2 6,-0.1 5,-0.1 -0.993 25.2 117.4-140.6 131.0 0.8 30.8 8.9 72 110 A H > - 0 0 68 -2,-0.4 3,-1.5 3,-0.3 53,-0.0 -0.848 65.8-101.7 167.8 153.5 -0.4 32.4 5.7 73 111 A Q T 3 S+ 0 0 106 1,-0.3 4,-0.1 -2,-0.2 52,-0.1 0.705 115.9 42.6 -71.2 -26.1 1.0 34.2 2.7 74 112 A H T 3 S+ 0 0 4 79,-0.1 80,-1.8 50,-0.1 2,-0.4 -0.146 99.9 83.7-116.3 37.3 0.0 37.7 3.7 75 113 A V B < S-f 154 0B 2 -3,-1.5 -3,-0.3 78,-0.3 2,-0.3 -0.995 91.0-102.5-134.5 138.5 1.0 37.5 7.3 76 114 A V - 0 0 7 78,-3.2 -6,-0.1 -2,-0.4 -2,-0.1 -0.422 48.8-113.3 -63.2 119.2 4.6 38.0 8.6 77 115 A G - 0 0 15 -2,-0.3 16,-2.3 -4,-0.1 2,-0.7 -0.266 19.0-139.1 -64.3 134.1 5.8 34.5 9.2 78 116 A F E +E 92 0A 32 -8,-0.7 14,-0.2 -11,-0.3 -1,-0.1 -0.827 25.7 171.5 -91.2 116.8 6.6 33.5 12.8 79 117 A H E - 0 0 104 12,-2.8 2,-0.2 -2,-0.7 13,-0.2 0.300 52.2 -78.5-111.1 7.6 9.8 31.4 13.0 80 118 A G E - 0 0 19 11,-0.5 11,-3.1 -16,-0.1 -1,-0.3 -0.617 37.7-127.1 131.5 176.0 10.3 31.1 16.8 81 119 A F E +E 90 0A 65 9,-0.3 2,-0.3 -2,-0.2 9,-0.2 -0.942 19.5 163.0-150.4 176.7 11.4 32.9 19.9 82 120 A F E -E 89 0A 15 7,-2.1 7,-4.1 -2,-0.3 2,-0.3 -0.897 19.2-138.7 177.2 168.6 13.6 32.6 23.0 83 121 A E E -E 88 0A 99 -2,-0.3 5,-0.2 5,-0.3 2,-0.1 -0.967 8.5-161.9-139.2 152.3 15.1 34.8 25.7 84 122 A D - 0 0 58 3,-1.7 -1,-0.1 -2,-0.3 5,-0.0 0.279 58.1 -82.4 -91.7-126.5 18.2 35.3 27.7 85 123 A N S S+ 0 0 136 -2,-0.1 3,-0.1 3,-0.0 -2,-0.0 0.582 126.1 36.1-113.5 -22.8 17.8 37.2 30.9 86 124 A D S S+ 0 0 84 1,-0.1 -38,-3.1 -39,-0.1 -37,-0.6 0.547 119.3 40.3-102.9 -9.2 17.9 40.8 29.5 87 125 A F E -D 47 0A 11 -40,-0.3 -3,-1.7 -39,-0.2 2,-0.5 -0.985 57.3-142.3-147.8 143.9 16.0 40.2 26.3 88 126 A V E -DE 46 83A 11 -42,-3.3 -42,-2.1 -2,-0.3 2,-0.5 -0.939 26.6-159.0-101.0 129.1 13.2 38.4 24.5 89 127 A F E -DE 45 82A 9 -7,-4.1 -7,-2.1 -2,-0.5 2,-0.4 -0.948 10.7-178.2-115.0 123.8 14.2 37.3 21.0 90 128 A V E -DE 44 81A 15 -46,-2.6 -46,-2.1 -2,-0.5 2,-0.6 -0.969 17.2-143.1-118.6 133.1 11.6 36.7 18.3 91 129 A V E -D 43 0A 4 -11,-3.1 -12,-2.8 -2,-0.4 -11,-0.5 -0.851 23.7-178.8-102.8 120.7 12.4 35.4 14.8 92 130 A L E -DE 42 78A 20 -50,-3.6 -50,-2.3 -2,-0.6 -14,-0.2 -0.838 36.8 -96.9-117.9 151.1 10.3 36.8 11.9 93 131 A E - 0 0 48 -16,-2.3 2,-0.5 -2,-0.3 -52,-0.1 -0.370 52.3-116.3 -51.4 136.5 10.2 36.3 8.1 94 132 A L - 0 0 22 -54,-0.5 2,-0.8 -18,-0.0 -1,-0.1 -0.726 20.1-156.2 -94.8 129.1 12.1 39.2 6.7 95 133 A C > - 0 0 18 -2,-0.5 3,-1.2 1,-0.1 52,-0.2 -0.859 6.9-170.6-105.1 106.3 10.3 41.8 4.6 96 134 A R T 3 S+ 0 0 108 -2,-0.8 51,-0.2 1,-0.3 -1,-0.1 0.590 78.8 57.3 -82.3 -9.6 13.0 43.3 2.4 97 135 A R T 3 S- 0 0 88 49,-2.6 -1,-0.3 1,-0.3 50,-0.1 -0.017 97.6-137.0-108.7 27.8 10.8 46.1 1.0 98 136 A R < - 0 0 164 -3,-1.2 48,-3.3 47,-0.1 -1,-0.3 -0.166 43.8 -42.6 58.7-140.6 9.9 47.6 4.3 99 137 A S B >> -G 145 0B 3 46,-0.3 4,-1.4 -3,-0.1 3,-0.9 -0.829 47.1-103.4-125.9 165.4 6.2 48.7 4.8 100 138 A L H 3> S+ 0 0 1 44,-3.5 4,-2.1 41,-0.3 42,-0.2 0.846 115.1 70.3 -48.5 -33.5 3.4 50.4 3.0 101 139 A L H 3> S+ 0 0 56 40,-2.4 4,-1.8 1,-0.2 -1,-0.2 0.913 99.2 44.1 -51.8 -50.8 4.2 53.4 5.2 102 140 A E H <> S+ 0 0 56 -3,-0.9 4,-0.7 1,-0.2 -1,-0.2 0.866 111.2 54.0 -63.7 -40.8 7.5 54.1 3.4 103 141 A L H X S+ 0 0 10 -4,-1.4 4,-1.2 1,-0.2 3,-0.4 0.835 109.7 49.7 -61.9 -33.6 5.9 53.6 0.0 104 142 A H H X S+ 0 0 21 -4,-2.1 4,-1.8 1,-0.2 -2,-0.2 0.859 102.1 59.3 -75.6 -35.4 3.3 56.1 1.0 105 143 A K H < S+ 0 0 131 -4,-1.8 -1,-0.2 1,-0.2 -2,-0.2 0.770 116.2 37.3 -57.6 -23.0 5.8 58.7 2.2 106 144 A R H < S+ 0 0 130 -4,-0.7 -1,-0.2 -3,-0.4 -2,-0.2 0.623 127.4 28.0-113.3 -20.5 7.2 58.6 -1.3 107 145 A R H < S- 0 0 22 -4,-1.2 -3,-0.2 1,-0.2 -2,-0.2 0.339 77.5-168.8-122.0 -3.1 4.3 58.2 -3.7 108 146 A K < + 0 0 114 -4,-1.8 101,-0.3 -5,-0.2 -1,-0.2 -0.136 70.0 27.0 36.0-126.2 1.6 59.9 -1.6 109 147 A A S S- 0 0 40 99,-0.3 98,-0.2 100,-0.1 2,-0.2 -0.272 85.5-144.2 -59.3 143.8 -1.6 59.0 -3.5 110 148 A L - 0 0 17 96,-3.2 2,-0.2 1,-0.1 -1,-0.1 -0.577 20.8 -96.4-100.7 165.5 -1.4 55.8 -5.5 111 149 A T > - 0 0 41 -2,-0.2 4,-1.9 1,-0.1 3,-0.3 -0.549 40.6-112.2 -74.1 151.1 -3.0 54.7 -8.8 112 150 A E H >> S+ 0 0 48 1,-0.2 4,-2.3 2,-0.2 3,-0.8 0.954 116.0 55.2 -52.3 -53.7 -6.2 52.8 -8.4 113 151 A P H 3> S+ 0 0 23 0, 0.0 4,-2.6 0, 0.0 -1,-0.2 0.900 107.8 49.9 -49.0 -42.9 -4.8 49.6 -9.7 114 152 A E H 3> S+ 0 0 0 -3,-0.3 4,-2.4 1,-0.2 5,-0.3 0.889 108.0 54.5 -60.3 -36.3 -2.0 49.7 -7.1 115 153 A A H <>S+ 0 0 0 -4,-2.0 3,-1.9 1,-0.3 5,-1.8 0.934 112.3 52.4 -60.9 -49.1 -7.1 36.2 10.7 130 168 A H H ><5S+ 0 0 21 -4,-2.9 3,-1.7 1,-0.3 -1,-0.3 0.866 104.7 56.1 -56.7 -36.6 -10.8 36.8 11.1 131 169 A R H 3<5S+ 0 0 177 -4,-2.0 -1,-0.3 -3,-0.3 -2,-0.2 0.698 106.9 52.3 -72.4 -13.9 -11.5 33.2 10.3 132 170 A N T <<5S- 0 0 37 -3,-1.9 -1,-0.3 -4,-0.9 -2,-0.2 0.066 119.8-109.2-104.1 25.5 -9.1 32.3 13.1 133 171 A R T < 5S+ 0 0 135 -3,-1.7 30,-3.5 1,-0.2 2,-0.5 0.824 76.9 134.0 58.4 33.5 -11.0 34.4 15.6 134 172 A V E < -I 162 0C 0 -5,-1.8 2,-0.5 28,-0.2 28,-0.2 -0.971 40.4-162.4-118.0 127.6 -8.0 36.9 15.7 135 173 A I E -I 161 0C 0 26,-2.6 26,-1.9 -2,-0.5 58,-0.0 -0.932 7.3-159.8-107.5 127.5 -8.4 40.7 15.5 136 174 A H - 0 0 1 -2,-0.5 23,-0.3 24,-0.2 -1,-0.2 0.968 17.0-169.3 -69.1 -52.1 -5.2 42.6 14.6 137 175 A R + 0 0 26 55,-0.1 44,-0.1 23,-0.1 -1,-0.1 0.348 69.3 55.4 82.9 0.0 -6.6 45.8 16.0 138 176 A D + 0 0 15 18,-0.1 2,-0.2 39,-0.1 40,-0.2 -0.007 62.0 164.0-152.3 38.4 -3.9 48.2 14.7 139 177 A L + 0 0 1 40,-0.1 40,-0.4 3,-0.1 2,-0.3 -0.462 22.0 142.8 -57.4 122.1 -3.9 47.7 10.9 140 178 A K > - 0 0 52 -2,-0.2 3,-1.6 38,-0.1 4,-0.4 -0.945 65.2 -88.6-157.6 169.2 -2.0 50.7 9.6 141 179 A L T 3 S+ 0 0 7 -2,-0.3 -40,-2.4 1,-0.3 3,-0.4 0.734 121.9 53.8 -61.7 -24.5 0.5 51.5 6.8 142 180 A G T 3 S+ 0 0 20 -42,-0.2 -1,-0.3 1,-0.2 -3,-0.1 0.574 105.2 53.1 -89.0 -10.1 3.5 50.7 8.9 143 181 A N S < S+ 0 0 6 -3,-1.6 12,-1.7 -5,-0.1 2,-0.9 0.338 89.5 87.1 -98.1 -0.3 2.4 47.3 9.9 144 182 A L E - H 0 154B 0 -4,-0.4 -44,-3.5 -3,-0.4 10,-0.2 -0.773 67.6-171.0-103.4 91.5 1.9 46.3 6.3 145 183 A F E -GH 99 153B 61 8,-2.1 8,-2.8 -2,-0.9 2,-0.5 -0.406 12.2-142.9 -83.2 154.6 5.3 45.0 5.3 146 184 A L E - H 0 152B 1 -48,-3.3 -49,-2.6 6,-0.2 6,-0.2 -0.972 8.5-154.1-122.4 126.1 6.3 44.1 1.7 147 185 A N > - 0 0 19 4,-1.9 3,-1.3 -2,-0.5 -52,-0.1 0.010 47.4 -73.4 -80.2-162.1 8.6 41.2 0.8 148 186 A E T 3 S+ 0 0 75 1,-0.3 -53,-0.0 2,-0.2 -1,-0.0 0.852 131.6 49.7 -73.6 -39.8 10.7 41.1 -2.3 149 187 A D T 3 S- 0 0 120 1,-0.0 127,-0.3 2,-0.0 -1,-0.3 0.032 122.5-104.9 -83.3 27.5 8.0 40.5 -4.9 150 188 A L < + 0 0 1 -3,-1.3 2,-0.3 1,-0.2 -2,-0.2 0.872 68.6 157.0 52.4 40.6 6.2 43.5 -3.3 151 189 A E - 0 0 46 -30,-0.0 -4,-1.9 124,-0.0 2,-0.3 -0.761 43.7-113.8 -94.3 145.8 3.7 41.2 -1.5 152 190 A V E - H 0 146B 0 -2,-0.3 2,-0.4 -6,-0.2 -6,-0.2 -0.560 31.4-178.3 -78.3 138.9 1.9 42.4 1.5 153 191 A K E - H 0 145B 14 -8,-2.8 -8,-2.1 -2,-0.3 -78,-0.3 -0.966 23.5-132.4-135.7 121.7 2.6 40.7 4.9 154 192 A I E -fH 75 144B 0 -80,-1.8 -78,-3.2 -2,-0.4 2,-0.3 -0.436 33.7-176.3 -71.6 145.5 0.7 41.9 8.0 155 193 A G + 0 0 0 -12,-1.7 -12,-0.1 1,-0.2 -1,-0.0 -0.828 36.1 45.4-140.9 173.6 2.9 42.5 11.0 156 194 A D - 0 0 50 -2,-0.3 3,-0.3 1,-0.1 -1,-0.2 0.968 41.9-171.9 55.0 90.9 3.0 43.4 14.7 157 195 A F + 0 0 0 1,-0.2 3,-0.5 2,-0.1 -1,-0.1 0.042 48.1 119.5 -98.5 26.6 0.4 41.5 16.7 158 196 A G S S+ 0 0 26 1,-0.3 -1,-0.2 -20,-0.1 -95,-0.1 0.449 85.5 32.9 -77.1 -1.2 1.0 43.4 19.9 159 197 A L S S+ 0 0 30 -23,-0.3 -1,-0.3 -3,-0.3 -2,-0.1 0.288 92.3 123.8-121.8 2.9 -2.5 44.7 20.0 160 198 A A - 0 0 6 -3,-0.5 2,-0.3 -22,-0.1 -24,-0.2 -0.399 43.5-167.8 -59.8 132.6 -3.9 41.5 18.4 161 199 A T E -I 135 0C 9 -26,-1.9 -26,-2.6 -2,-0.1 2,-0.4 -0.949 16.5-125.7-125.2 149.2 -6.5 39.9 20.7 162 200 A K E -I 134 0C 56 -2,-0.3 2,-0.6 -28,-0.2 -28,-0.2 -0.762 16.5-130.8 -94.2 133.9 -8.1 36.5 20.5 163 201 A V - 0 0 11 -30,-3.5 3,-0.1 -2,-0.4 28,-0.0 -0.781 22.2-173.0 -82.5 119.4 -11.9 36.0 20.3 164 202 A E + 0 0 122 -2,-0.6 2,-0.3 1,-0.2 -1,-0.1 0.662 61.4 4.5 -93.5 -18.1 -12.7 33.4 22.9 165 203 A Y S > S- 0 0 137 -32,-0.0 3,-2.2 0, 0.0 -1,-0.2 -0.952 87.3 -80.3-166.5 144.9 -16.4 32.8 22.2 166 204 A D T 3 S+ 0 0 154 -2,-0.3 -2,-0.0 1,-0.3 0, 0.0 -0.084 114.3 18.2 -44.5 141.0 -19.2 33.8 19.8 167 205 A G T 3 S+ 0 0 68 1,-0.2 -1,-0.3 -4,-0.0 -4,-0.0 0.228 85.0 153.5 85.5 -15.6 -20.6 37.2 20.6 168 206 A E < - 0 0 25 -3,-2.2 2,-0.6 1,-0.1 -1,-0.2 -0.159 30.9-156.6 -51.2 134.2 -17.8 38.4 22.8 169 207 A R - 0 0 88 22,-0.1 2,-0.3 20,-0.0 22,-0.2 -0.957 14.5-137.4-111.6 111.1 -17.3 42.1 22.9 170 208 A K B -J 190 0D 36 20,-2.0 20,-2.3 -2,-0.6 19,-0.1 -0.526 16.9-163.4 -65.1 124.4 -13.7 43.0 23.9 171 209 A K + 0 0 156 -2,-0.3 2,-0.3 18,-0.2 18,-0.2 0.674 61.3 28.2 -92.6 -18.4 -14.3 45.8 26.3 172 210 A T - 0 0 111 18,-0.1 2,-0.4 16,-0.1 -1,-0.1 -0.953 52.8-158.7-140.9 159.5 -10.8 47.4 26.4 173 211 A L - 0 0 26 -2,-0.3 2,-2.0 11,-0.1 -14,-0.0 -0.892 16.2-147.8-142.1 108.0 -7.7 47.9 24.2 174 212 A C + 0 0 62 -2,-0.4 2,-0.3 2,-0.1 -2,-0.0 -0.499 68.9 36.0 -84.2 81.2 -4.5 48.6 26.0 175 213 A G S S- 0 0 40 -2,-2.0 -2,-0.1 2,-0.1 -16,-0.0 -0.954 86.6 -85.5 164.3-176.9 -2.7 50.8 23.5 176 214 A T - 0 0 100 -2,-0.3 -2,-0.1 -38,-0.0 4,-0.0 -0.681 36.1-160.7-120.9 80.4 -3.1 53.5 21.0 177 215 A P > - 0 0 3 0, 0.0 3,-0.5 0, 0.0 -39,-0.1 -0.250 16.4-135.9 -57.5 148.3 -3.9 52.2 17.5 178 216 A N T 3 S+ 0 0 101 1,-0.2 2,-1.8 -40,-0.2 -38,-0.1 0.998 101.7 31.9 -59.0 -78.9 -3.2 54.6 14.6 179 217 A Y T 3 S- 0 0 20 -40,-0.4 -1,-0.2 -41,-0.0 2,-0.2 -0.492 91.3-176.2 -81.3 66.7 -6.5 54.1 12.6 180 218 A I < - 0 0 13 -2,-1.8 -42,-0.1 -3,-0.5 15,-0.0 -0.472 22.3-119.4 -79.6 137.6 -8.7 53.5 15.7 181 219 A A >> - 0 0 2 -2,-0.2 4,-1.1 -44,-0.1 3,-1.1 -0.341 18.5-117.4 -80.0 154.6 -12.3 52.6 15.2 182 220 A P H 3> S+ 0 0 5 0, 0.0 4,-2.2 0, 0.0 3,-0.5 0.867 111.1 56.2 -58.0 -44.0 -15.2 54.7 16.6 183 221 A E H 34>S+ 0 0 8 1,-0.3 5,-1.7 2,-0.2 6,-0.5 0.722 101.6 57.8 -67.8 -23.8 -16.5 52.0 18.9 184 222 A V H X45S+ 0 0 22 -3,-1.1 3,-0.9 3,-0.2 -1,-0.3 0.916 109.3 44.8 -68.1 -41.8 -13.2 51.6 20.6 185 223 A L H 3<5S+ 0 0 33 -4,-1.1 -2,-0.2 -3,-0.5 -1,-0.1 0.862 104.7 59.3 -73.0 -40.0 -13.2 55.3 21.6 186 224 A S T 3<5S- 0 0 55 -4,-2.2 -1,-0.3 1,-0.1 -2,-0.1 0.098 108.0-130.0 -76.4 23.0 -16.8 55.3 22.8 187 225 A K T < 5 + 0 0 188 -3,-0.9 -3,-0.2 1,-0.2 -2,-0.1 0.783 67.4 133.1 31.4 64.0 -15.5 52.7 25.2 188 226 A K < - 0 0 155 -5,-1.7 -1,-0.2 -18,-0.1 -4,-0.1 0.459 69.5 -83.6-130.4 -10.5 -18.4 50.6 24.0 189 227 A G - 0 0 2 -6,-0.5 2,-0.3 -18,-0.2 -18,-0.2 0.373 49.1-158.5 99.7 125.2 -17.2 47.1 23.2 190 228 A H B +J 170 0D 3 -20,-2.3 -20,-2.0 -18,-0.1 2,-0.2 -0.889 16.3 169.6-138.0 158.4 -15.7 46.0 19.9 191 229 A S > - 0 0 11 -2,-0.3 3,-2.1 -22,-0.2 4,-0.3 -0.526 61.3 -30.6-143.3-141.1 -15.0 43.1 17.7 192 230 A F T >> S+ 0 0 53 1,-0.3 3,-1.7 -2,-0.2 4,-0.8 0.708 114.5 74.8 -61.3 -23.7 -13.8 42.2 14.2 193 231 A E H 3> S+ 0 0 42 1,-0.3 4,-3.0 2,-0.2 -1,-0.3 0.718 78.5 75.9 -67.3 -17.5 -15.2 45.3 12.5 194 232 A V H <> S+ 0 0 6 -3,-2.1 4,-2.3 1,-0.2 -1,-0.3 0.887 95.9 49.6 -60.1 -35.5 -12.5 47.4 14.0 195 233 A D H <> S+ 0 0 0 -3,-1.7 4,-2.6 -4,-0.3 -1,-0.2 0.855 107.6 52.2 -72.3 -32.5 -10.2 45.8 11.4 196 234 A V H X S+ 0 0 2 -4,-0.8 4,-2.2 2,-0.2 -2,-0.2 0.937 109.5 51.6 -65.8 -43.8 -12.7 46.6 8.6 197 235 A W H X S+ 0 0 2 -4,-3.0 4,-1.7 2,-0.2 -2,-0.2 0.938 110.0 47.7 -52.2 -53.0 -12.7 50.2 9.9 198 236 A S H >X S+ 0 0 4 -4,-2.3 4,-2.7 1,-0.2 3,-0.5 0.948 109.7 52.1 -57.3 -50.6 -8.8 50.4 9.8 199 237 A I H 3X S+ 0 0 4 -4,-2.6 4,-2.9 1,-0.3 -1,-0.2 0.874 104.7 59.4 -54.6 -36.1 -8.8 48.9 6.3 200 238 A G H 3X S+ 0 0 0 -4,-2.2 4,-1.9 1,-0.2 -1,-0.3 0.919 107.7 43.7 -56.4 -45.0 -11.3 51.7 5.4 201 239 A C H S+ 0 0 6 -4,-1.9 4,-4.3 1,-0.2 5,-0.6 0.970 113.1 49.9 -52.2 -56.4 -8.6 56.3 1.8 205 243 A T H X5S+ 0 0 0 -4,-2.7 4,-1.2 1,-0.3 -2,-0.2 0.814 111.7 47.0 -58.8 -36.2 -5.0 57.0 2.6 206 244 A L H <5S+ 0 0 4 -4,-2.5 -96,-3.2 -5,-0.2 -1,-0.3 0.866 122.6 34.2 -76.3 -35.8 -3.8 55.0 -0.4 207 245 A L H <5S+ 0 0 8 -4,-2.2 -2,-0.2 -5,-0.3 -3,-0.2 0.915 127.2 36.2 -84.0 -44.3 -6.2 56.6 -2.8 208 246 A V H <5S- 0 0 17 -4,-4.3 -99,-0.3 -5,-0.3 -3,-0.2 0.747 100.8-126.3 -85.6 -24.7 -6.4 60.1 -1.4 209 247 A G S < - 0 0 27 0, 0.0 3,-1.2 0, 0.0 -9,-0.1 -0.344 36.3-124.7 -67.9 140.5 -5.4 59.9 6.4 212 250 A P T 3 S+ 0 0 6 0, 0.0 19,-0.3 0, 0.0 -10,-0.0 0.674 104.9 27.6 -59.9 -20.1 -9.2 60.3 6.5 213 251 A F T 3 S+ 0 0 11 17,-0.1 11,-0.1 2,-0.0 12,-0.1 0.184 79.9 150.8-131.7 23.0 -9.2 62.0 9.9 214 252 A E < + 0 0 135 -3,-1.2 2,-0.3 10,-0.1 4,-0.0 -0.272 10.4 154.6 -64.7 139.3 -5.8 63.8 10.3 215 253 A T - 0 0 35 1,-0.0 6,-0.1 0, 0.0 -2,-0.0 -0.952 56.3-101.3-152.6 165.6 -5.6 67.0 12.5 216 254 A S S S+ 0 0 139 -2,-0.3 2,-0.5 1,-0.1 -2,-0.0 0.744 107.2 53.7 -67.7 -19.9 -2.8 68.7 14.5 217 255 A C S >> S- 0 0 50 1,-0.2 4,-2.0 2,-0.0 3,-0.7 -0.962 71.4-146.1-123.1 134.2 -4.2 67.2 17.8 218 256 A L H 3> S+ 0 0 88 -2,-0.5 4,-2.8 1,-0.3 5,-0.2 0.925 101.3 53.0 -58.1 -51.4 -4.9 63.6 18.5 219 257 A K H 3> S+ 0 0 139 1,-0.2 4,-1.4 2,-0.2 -1,-0.3 0.759 108.3 52.5 -58.8 -24.7 -7.9 64.3 20.7 220 258 A E H <> S+ 0 0 105 -3,-0.7 4,-2.9 2,-0.2 -1,-0.2 0.885 107.6 51.3 -75.7 -40.8 -9.4 66.4 17.9 221 259 A T H X S+ 0 0 20 -4,-2.0 4,-2.7 2,-0.2 -2,-0.2 0.962 108.0 51.8 -55.2 -51.8 -8.9 63.5 15.6 222 260 A Y H X S+ 0 0 37 -4,-2.8 4,-2.5 1,-0.2 -1,-0.2 0.882 108.3 52.6 -54.8 -39.4 -10.7 61.2 18.0 223 261 A L H X S+ 0 0 84 -4,-1.4 4,-2.6 -5,-0.2 5,-0.3 0.979 108.2 50.6 -58.4 -54.4 -13.5 63.7 18.1 224 262 A R H <>S+ 0 0 92 -4,-2.9 5,-3.3 1,-0.2 -2,-0.2 0.895 110.8 48.7 -48.4 -49.3 -13.7 63.6 14.3 225 263 A I H ><5S+ 0 0 6 -4,-2.7 3,-2.0 3,-0.2 -1,-0.2 0.969 110.6 49.5 -58.8 -55.8 -13.8 59.8 14.3 226 264 A K H 3<5S+ 0 0 117 -4,-2.5 -2,-0.2 1,-0.3 -1,-0.2 0.913 117.7 39.9 -48.5 -52.1 -16.5 59.7 16.9 227 265 A K T 3<5S- 0 0 138 -4,-2.6 -1,-0.3 -5,-0.2 -2,-0.2 0.395 112.7-124.9 -78.6 2.4 -18.7 62.2 15.0 228 266 A N T < 5 + 0 0 54 -3,-2.0 2,-1.0 -5,-0.3 -3,-0.2 0.918 46.5 171.9 55.5 48.0 -17.6 60.5 11.8 229 267 A E < + 0 0 92 -5,-3.3 2,-0.3 -6,-0.2 -1,-0.2 -0.745 20.7 111.2 -99.1 94.6 -16.3 63.7 10.4 230 268 A Y - 0 0 49 -2,-1.0 2,-0.3 -5,-0.1 -17,-0.1 -0.894 43.7-147.3-142.7 178.1 -14.4 63.2 7.1 231 269 A S - 0 0 85 -19,-0.3 -2,-0.0 -2,-0.3 0, 0.0 -0.994 12.7-132.1-151.6 148.8 -14.8 63.9 3.4 232 270 A I - 0 0 37 -2,-0.3 9,-0.0 1,-0.0 -2,-0.0 -0.866 33.2-112.6-107.3 117.7 -13.8 62.2 0.2 233 271 A P > - 0 0 33 0, 0.0 3,-0.8 0, 0.0 8,-0.1 -0.022 25.1-121.6 -45.7 149.9 -12.1 64.3 -2.4 234 272 A K T 3 S+ 0 0 216 1,-0.2 -2,-0.0 4,-0.0 0, 0.0 0.694 106.3 62.5 -74.9 -17.7 -14.3 64.8 -5.5 235 273 A H T 3 S+ 0 0 135 2,-0.1 -1,-0.2 -27,-0.0 2,-0.2 0.686 77.3 99.7 -81.7 -22.6 -11.7 63.3 -7.9 236 274 A I S < S- 0 0 19 -3,-0.8 -4,-0.0 1,-0.1 -28,-0.0 -0.484 90.0-100.5 -60.3 134.9 -11.7 59.8 -6.2 237 275 A N > - 0 0 77 -2,-0.2 4,-2.7 1,-0.1 5,-0.1 -0.122 23.6-119.1 -58.7 155.2 -13.9 57.6 -8.3 238 276 A P H > S+ 0 0 100 0, 0.0 4,-1.4 0, 0.0 -1,-0.1 0.768 112.5 49.1 -71.1 -24.6 -17.5 57.0 -7.2 239 277 A V H > S+ 0 0 44 2,-0.2 4,-1.4 3,-0.1 27,-0.2 0.941 114.0 45.1 -78.0 -48.5 -17.0 53.3 -6.9 240 278 A A H >> S+ 0 0 0 1,-0.2 4,-1.6 2,-0.2 3,-0.9 0.969 112.3 53.6 -49.8 -59.8 -13.8 53.6 -4.8 241 279 A A H >X S+ 0 0 13 -4,-2.7 4,-2.2 1,-0.3 3,-0.6 0.872 105.5 50.6 -46.8 -51.9 -15.4 56.3 -2.7 242 280 A S H 3X S+ 0 0 35 -4,-1.4 4,-3.2 1,-0.3 -1,-0.3 0.770 103.3 57.8 -73.1 -25.2 -18.4 54.3 -1.7 243 281 A L H > S- 0 0 83 1,-0.1 3,-1.9 -69,-0.1 4,-0.6 -0.803 70.8-156.7 -92.5 113.6 -21.9 51.6 13.5 252 290 A P G >4 S+ 0 0 15 0, 0.0 3,-0.9 0, 0.0 -1,-0.1 0.804 88.9 68.6 -61.2 -28.5 -19.8 48.4 13.1 253 291 A T G 34 S+ 0 0 114 1,-0.3 4,-0.1 -3,-0.1 -3,-0.1 0.488 101.2 50.2 -68.9 -1.0 -22.9 46.4 12.2 254 292 A A G <4 S+ 0 0 40 -3,-1.9 -1,-0.3 -5,-0.1 3,-0.1 0.601 87.1 96.0-109.9 -20.4 -23.1 48.3 9.0 255 293 A R S << S- 0 0 9 -3,-0.9 -8,-0.2 -4,-0.6 -9,-0.1 -0.504 86.1-100.5 -76.3 139.7 -19.5 47.9 7.8 256 294 A P - 0 0 15 0, 0.0 2,-0.1 0, 0.0 -1,-0.1 -0.125 39.2-111.6 -48.3 152.2 -18.8 45.1 5.3 257 295 A T > - 0 0 76 1,-0.1 4,-0.7 -3,-0.1 3,-0.5 -0.489 28.8-108.0 -81.8 165.5 -17.3 41.9 6.8 258 296 A I H > S+ 0 0 3 1,-0.2 4,-0.5 2,-0.2 -131,-0.2 0.823 117.5 55.7 -63.2 -24.1 -13.8 41.0 5.8 259 297 A N H 4 S+ 0 0 93 1,-0.2 -1,-0.2 2,-0.2 3,-0.2 0.784 105.5 44.1 -86.2 -29.3 -15.2 38.2 3.7 260 298 A E H >> S+ 0 0 101 -3,-0.5 4,-0.7 1,-0.2 3,-0.7 0.479 93.7 91.2 -90.1 -3.3 -17.7 40.1 1.5 261 299 A L H >< S+ 0 0 3 -4,-0.7 3,-1.9 1,-0.2 6,-0.2 0.956 78.7 52.6 -57.5 -54.7 -15.0 42.7 1.0 262 300 A L T 3< S+ 0 0 40 -4,-0.5 -1,-0.2 1,-0.3 6,-0.2 0.728 101.1 64.8 -61.4 -17.4 -13.3 41.3 -2.1 263 301 A N T <4 S+ 0 0 119 -3,-0.7 -1,-0.3 -4,-0.2 5,-0.3 0.797 73.6 117.2 -71.7 -28.9 -16.7 41.1 -3.8 264 302 A D S XX S- 0 0 29 -3,-1.9 3,-2.6 -4,-0.7 4,-1.7 -0.046 79.4-116.9 -47.7 138.0 -17.2 44.8 -3.9 265 303 A E H 3> S+ 0 0 106 1,-0.3 4,-2.8 2,-0.2 -1,-0.2 0.761 110.6 75.1 -50.2 -29.0 -17.4 46.2 -7.3 266 304 A F H 34 S+ 0 0 3 -27,-0.2 -1,-0.3 1,-0.2 -26,-0.1 0.906 111.0 27.8 -48.0 -43.4 -14.3 48.2 -6.6 267 305 A F H X4 S+ 0 0 11 -3,-2.6 3,-1.2 -6,-0.2 -2,-0.2 0.930 123.9 46.4 -84.2 -49.3 -12.4 44.9 -7.0 268 306 A T H 3< S+ 0 0 91 -4,-1.7 -3,-0.2 1,-0.3 -2,-0.2 0.736 117.6 39.4 -80.3 -21.6 -14.6 43.0 -9.4 269 307 A S T 3< S+ 0 0 85 -4,-2.8 2,-0.3 -5,-0.2 -1,-0.3 0.241 109.0 80.3-106.6 13.6 -15.2 45.7 -12.0 270 308 A G S < S- 0 0 22 -3,-1.2 2,-0.5 -5,-0.2 -4,-0.0 -0.835 85.9-102.8-121.9 157.8 -11.7 47.0 -11.8 271 309 A Y - 0 0 134 -2,-0.3 -155,-0.2 1,-0.0 -154,-0.2 -0.664 33.7-170.7 -78.5 124.2 -8.4 46.0 -13.1 272 310 A I - 0 0 53 -2,-0.5 -158,-0.1 -156,-0.1 -160,-0.0 -0.934 19.9-132.1-118.3 110.0 -6.2 44.3 -10.5 273 311 A P - 0 0 6 0, 0.0 3,-0.1 0, 0.0 0, 0.0 -0.054 5.0-140.5 -52.7 160.3 -2.5 43.8 -11.6 274 312 A A S S- 0 0 91 1,-0.3 2,-0.3 0, 0.0 0, 0.0 0.789 82.0 -4.8 -90.8 -37.3 -1.1 40.4 -11.0 275 313 A R S S- 0 0 210 -124,-0.0 -1,-0.3 0, 0.0 -125,-0.1 -0.892 73.4-121.0-143.7 174.3 2.2 41.7 -9.9 276 314 A L - 0 0 14 -127,-0.3 2,-0.2 -2,-0.3 5,-0.0 -0.960 20.8-115.4-124.2 142.7 3.9 45.0 -9.6 277 315 A P > - 0 0 50 0, 0.0 3,-1.6 0, 0.0 4,-0.2 -0.516 23.2-131.6 -64.3 136.9 7.1 46.5 -11.1 278 316 A I G > S+ 0 0 71 1,-0.3 3,-1.3 -2,-0.2 4,-0.1 0.678 109.8 72.1 -65.2 -14.9 9.6 47.3 -8.3 279 317 A T G >> S+ 0 0 67 1,-0.3 3,-3.9 2,-0.2 4,-2.3 0.914 78.8 72.9 -57.4 -43.0 9.7 50.5 -10.2 280 318 A C G <4 S+ 0 0 0 -3,-1.6 -1,-0.3 1,-0.3 -2,-0.2 0.644 78.1 79.3 -55.2 -11.8 6.3 51.1 -8.8 281 319 A L G <4 S+ 0 0 33 -3,-1.3 -1,-0.3 -4,-0.2 -2,-0.2 0.699 120.2 1.3 -62.9 -21.8 8.3 51.7 -5.6 282 320 A T T <4 S+ 0 0 57 -3,-3.9 -2,-0.2 1,-0.3 -1,-0.1 0.436 126.0 61.6-147.9 -11.5 9.1 55.2 -6.8 283 321 A I S < S- 0 0 84 -4,-2.3 -1,-0.3 -5,-0.1 -176,-0.1 -0.990 84.6-112.0-125.6 130.1 7.4 55.7 -10.2 284 322 A P - 0 0 52 0, 0.0 2,-0.2 0, 0.0 -3,-0.1 -0.365 38.8-124.3 -55.5 127.5 3.7 55.6 -10.8 285 323 A P - 0 0 10 0, 0.0 -171,-0.1 0, 0.0 -174,-0.0 -0.540 18.2-162.0 -75.5 140.7 3.0 52.5 -12.9 286 324 A R - 0 0 209 -2,-0.2 0, 0.0 -175,-0.0 0, 0.0 0.692 16.7-146.7 -97.1 -22.1 1.2 53.2 -16.2 287 325 A F + 0 0 64 1,-0.0 0, 0.0 2,-0.0 0, 0.0 0.920 31.1 178.3 58.0 45.2 0.0 49.6 -16.9 288 326 A S - 0 0 96 1,-0.1 -1,-0.0 0, 0.0 -2,-0.0 0.015 38.8-112.3 -68.4-174.6 0.3 50.1 -20.7 289 327 A I 0 0 170 1,-0.4 -1,-0.1 0, 0.0 -2,-0.0 0.565 360.0 360.0-108.6 -10.6 -0.4 47.3 -23.1 290 328 A A 0 0 134 0, 0.0 -1,-0.4 0, 0.0 0, 0.0 -0.794 360.0 360.0 170.9 360.0 3.1 46.7 -24.4