==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=16-NOV-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER PHOSPHATE-BINDING PROTEIN 07-MAY-12 4F1V . COMPND 2 MOLECULE: PUTATIVE ALKALINE PHOSPHATASE; . SOURCE 2 ORGANISM_SCIENTIFIC: PSEUDOMONAS FLUORESCENS; . AUTHOR D.LIEBSCHNER,M.ELIAS,D.S.TAWFIK,S.MONIOT,B.FOURNIER,K.SCOTT, . 372 1 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14395.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 223 59.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 24 6.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 33 8.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 17 4.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 50 13.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 79 21.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 1 0 0 2 2 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 7 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1000 A M 0 0 149 0, 0.0 3,-0.0 0, 0.0 54,-0.0 0.000 360.0 360.0 360.0 123.7 -17.5 -24.7 18.5 2 1001 A D - 0 0 90 1,-0.1 2,-0.5 23,-0.1 23,-0.2 -0.244 360.0-103.4 -58.7 156.2 -17.9 -21.1 17.5 3 1002 A I B -a 25 0A 0 21,-3.0 23,-2.7 55,-0.1 2,-0.5 -0.746 38.5-148.2 -87.9 125.3 -14.8 -19.1 16.6 4 1003 A N + 0 0 6 -2,-0.5 54,-2.8 52,-0.2 55,-1.5 -0.882 23.8 163.7-107.6 123.8 -13.9 -16.8 19.5 5 1004 A G E +b 59 0B 1 -2,-0.5 24,-1.5 21,-0.2 2,-0.3 -0.869 6.3 134.2-133.1 166.6 -12.3 -13.4 19.1 6 1005 A G E +bc 60 29B 0 53,-0.6 55,-2.0 -2,-0.3 2,-0.4 -0.975 14.9 109.1 172.2-179.4 -11.7 -10.3 21.2 7 1006 A G E +bc 61 30B 0 22,-2.4 25,-2.5 -2,-0.3 24,-2.3 -0.987 56.5 63.6 133.6-128.3 -9.1 -7.7 22.2 8 1007 A A - 0 0 0 53,-2.6 54,-0.1 -2,-0.4 -1,-0.1 -0.003 49.3-161.3 -38.6 130.9 -8.8 -4.1 21.2 9 1008 A T S > S+ 0 0 7 1,-0.2 3,-1.8 21,-0.1 4,-0.4 0.736 77.9 82.0 -84.0 -24.4 -11.7 -1.9 22.4 10 1009 A L T 3 S+ 0 0 0 1,-0.3 201,-0.3 2,-0.1 202,-0.3 0.875 109.0 22.7 -50.8 -45.9 -10.9 0.9 19.9 11 1010 A P T >> S+ 0 0 0 0, 0.0 4,-1.7 0, 0.0 3,-0.8 0.150 87.6 115.3-104.8 16.7 -12.8 -0.9 17.0 12 1011 A Q H <> S+ 0 0 12 -3,-1.8 4,-1.7 1,-0.3 -2,-0.1 0.867 73.5 56.6 -63.4 -30.8 -15.1 -3.2 19.1 13 1012 A A H 34 S+ 0 0 22 -4,-0.4 4,-0.4 -3,-0.2 -1,-0.3 0.824 105.2 53.5 -69.8 -27.4 -18.3 -1.4 17.8 14 1013 A L H X4 S+ 0 0 0 -3,-0.8 3,-1.7 2,-0.2 -1,-0.2 0.969 110.2 44.7 -63.9 -52.3 -17.2 -2.3 14.2 15 1014 A Y H 3< S+ 0 0 1 -4,-1.7 6,-0.4 1,-0.3 13,-0.4 0.771 113.0 54.2 -71.1 -15.0 -16.8 -6.0 15.0 16 1015 A Q T 3< S+ 0 0 77 -4,-1.7 2,-0.3 -5,-0.2 -1,-0.3 0.435 80.0 111.1 -91.3 -4.2 -20.1 -5.9 16.9 17 1016 A T S X S- 0 0 48 -3,-1.7 3,-2.2 -4,-0.4 4,-0.5 -0.593 86.4 -97.2 -66.7 130.3 -22.0 -4.4 13.9 18 1017 A S T 3 S+ 0 0 124 -2,-0.3 -1,-0.1 1,-0.3 -2,-0.1 -0.196 105.7 12.3 -51.1 135.7 -24.4 -7.1 12.7 19 1018 A G T 3 S+ 0 0 39 2,-0.3 -1,-0.3 -4,-0.1 4,-0.1 0.244 94.1 104.0 82.6 -10.5 -22.9 -9.0 9.7 20 1019 A V S < S+ 0 0 2 -3,-2.2 2,-0.4 -6,-0.2 -2,-0.1 0.952 82.2 49.4 -69.3 -48.6 -19.3 -7.7 10.0 21 1020 A L S S- 0 0 20 -4,-0.5 -2,-0.3 -6,-0.4 3,-0.1 -0.769 94.2-138.4 -83.2 139.5 -18.2 -11.1 11.5 22 1021 A T > - 0 0 32 -2,-0.4 3,-1.8 1,-0.2 -1,-0.1 -0.018 39.9 -37.4 -94.2-169.9 -19.5 -14.0 9.4 23 1022 A A T 3 S+ 0 0 77 1,-0.3 -1,-0.2 -4,-0.1 291,-0.1 -0.156 123.6 19.7 -58.5 139.8 -21.0 -17.4 10.1 24 1023 A G T 3 S+ 0 0 19 1,-0.3 -21,-3.0 -3,-0.1 2,-0.5 0.287 90.9 125.0 89.9 -12.3 -19.6 -19.3 13.0 25 1024 A F B < -a 3 0A 14 -3,-1.8 -1,-0.3 -23,-0.2 -21,-0.2 -0.715 54.3-139.4 -86.8 124.9 -18.1 -16.2 14.8 26 1025 A A - 0 0 19 -23,-2.7 -21,-0.2 -2,-0.5 2,-0.1 -0.323 44.7 -77.2 -66.6 158.7 -19.1 -15.6 18.3 27 1026 A Q - 0 0 131 1,-0.1 -1,-0.1 -23,-0.1 -22,-0.1 -0.374 58.0-101.1 -66.0 140.5 -19.7 -11.9 19.2 28 1027 A Y - 0 0 5 -13,-0.4 2,-0.6 -16,-0.1 -22,-0.3 -0.287 30.1-143.9 -65.0 139.7 -16.4 -10.0 19.7 29 1028 A I E -c 6 0B 35 -24,-1.5 -22,-2.4 -3,-0.1 2,-0.7 -0.925 6.5-147.1-112.8 113.4 -15.3 -9.3 23.2 30 1029 A G E +c 7 0B 27 -2,-0.6 -22,-0.2 -24,-0.2 -21,-0.1 -0.723 42.3 137.4 -87.7 116.4 -13.6 -6.0 23.9 31 1030 A V - 0 0 34 -24,-2.3 4,-0.2 -2,-0.7 -23,-0.2 0.342 68.4 -82.2-134.6 -2.2 -10.9 -6.3 26.7 32 1031 A G > - 0 0 0 -25,-2.5 4,-2.1 2,-0.1 -24,-0.2 -0.012 41.5 -89.8 103.5 149.5 -7.9 -4.2 25.4 33 1032 A S H > S+ 0 0 1 -26,-0.2 4,-2.8 1,-0.2 5,-0.2 0.862 122.5 55.2 -65.7 -39.0 -5.1 -5.1 23.0 34 1033 A G H > S+ 0 0 15 111,-2.1 4,-2.3 1,-0.2 -1,-0.2 0.943 111.5 45.4 -58.8 -45.3 -2.7 -6.4 25.6 35 1034 A N H > S+ 0 0 57 110,-0.5 4,-2.5 -4,-0.2 -2,-0.2 0.886 112.0 52.7 -64.0 -39.0 -5.4 -8.9 26.7 36 1035 A G H X S+ 0 0 0 -4,-2.1 4,-2.2 2,-0.2 5,-0.2 0.931 110.0 47.0 -63.3 -46.1 -6.2 -9.8 23.1 37 1036 A K H X S+ 0 0 13 -4,-2.8 4,-2.9 1,-0.2 5,-0.3 0.942 114.2 47.0 -59.9 -45.4 -2.6 -10.6 22.2 38 1037 A A H X S+ 0 0 23 -4,-2.3 4,-1.9 -5,-0.2 6,-0.4 0.901 109.5 55.1 -65.4 -40.5 -2.2 -12.7 25.4 39 1038 A A H X>S+ 0 0 0 -4,-2.5 5,-1.8 -5,-0.2 4,-0.6 0.940 115.7 37.2 -54.8 -51.0 -5.5 -14.5 24.7 40 1039 A F H ><5S+ 0 0 0 -4,-2.2 3,-0.8 3,-0.2 -2,-0.2 0.954 115.9 50.7 -67.3 -51.5 -4.3 -15.6 21.2 41 1040 A L H 3<5S+ 0 0 18 -4,-2.9 -1,-0.2 1,-0.3 -2,-0.2 0.802 124.5 28.4 -61.7 -31.7 -0.7 -16.2 21.9 42 1041 A N H 3<5S- 0 0 102 -4,-1.9 -1,-0.3 -5,-0.3 -2,-0.2 0.331 102.8-121.5-107.9 1.0 -1.4 -18.5 24.9 43 1042 A N T <<5 + 0 0 32 -3,-0.8 2,-0.6 -4,-0.6 -3,-0.2 0.953 58.8 156.2 49.3 54.3 -4.8 -19.8 23.9 44 1043 A D > < - 0 0 48 -5,-1.8 3,-1.7 -6,-0.4 4,-0.3 -0.854 28.6-177.1-119.9 94.4 -6.1 -18.4 27.1 45 1044 A Y G >> S+ 0 0 8 -2,-0.6 4,-2.5 10,-0.5 3,-1.8 0.725 75.9 77.7 -66.8 -17.6 -9.8 -17.6 27.0 46 1045 A T G 34 S+ 0 0 45 1,-0.3 -1,-0.3 2,-0.2 7,-0.1 0.760 84.1 65.5 -64.9 -18.0 -9.8 -16.2 30.5 47 1046 A K G <4 S+ 0 0 79 -3,-1.7 -1,-0.3 1,-0.2 -2,-0.2 0.711 110.4 37.2 -72.4 -21.5 -8.2 -13.0 28.9 48 1047 A F T <4 S+ 0 0 10 -3,-1.8 2,-0.5 1,-0.3 -2,-0.2 0.844 136.3 15.6 -88.7 -52.8 -11.6 -12.6 27.1 49 1048 A Q S >< S- 0 0 78 -4,-2.5 3,-2.1 3,-0.3 -1,-0.3 -0.920 82.9-132.8-129.8 106.2 -13.9 -13.8 29.9 50 1049 A A T 3 S+ 0 0 95 -2,-0.5 -3,-0.1 1,-0.3 3,-0.1 -0.243 92.5 19.8 -56.0 139.7 -12.4 -13.9 33.4 51 1050 A G T 3 S+ 0 0 77 1,-0.2 2,-0.5 -5,-0.0 -1,-0.3 0.443 97.5 110.7 82.8 -1.5 -13.3 -17.3 35.0 52 1051 A V < + 0 0 39 -3,-2.1 -3,-0.3 1,-0.1 -4,-0.2 -0.936 24.2 154.5-116.1 118.6 -14.1 -19.1 31.8 53 1052 A T + 0 0 118 -2,-0.5 -8,-0.1 -8,-0.1 -1,-0.1 0.407 50.5 90.0-122.9 5.3 -11.8 -21.9 30.6 54 1053 A N S S+ 0 0 132 -9,-0.1 2,-0.3 2,-0.0 -1,-0.1 0.185 81.0 66.1 -96.9 19.7 -14.1 -24.2 28.5 55 1054 A K S S- 0 0 89 -3,-0.1 -10,-0.5 317,-0.1 2,-0.2 -0.940 72.0-130.3-135.0 154.8 -13.4 -22.4 25.2 56 1055 A N - 0 0 25 -2,-0.3 2,-0.5 315,-0.2 -52,-0.2 -0.646 22.2-121.1 -96.2 160.3 -10.4 -21.8 22.8 57 1056 A V + 0 0 0 -2,-0.2 -52,-0.2 -18,-0.2 3,-0.1 -0.904 29.3 174.1-102.5 129.5 -9.3 -18.5 21.4 58 1057 A H - 0 0 2 -54,-2.8 241,-0.6 -2,-0.5 2,-0.3 0.680 60.6 -5.1-107.9 -26.5 -9.2 -18.3 17.6 59 1058 A W E -bD 5 298B 0 -55,-1.5 -53,-0.6 239,-0.1 2,-0.3 -0.979 56.5-147.4-160.5 165.0 -8.3 -14.7 16.8 60 1059 A A E -bD 6 297B 0 237,-2.4 237,-2.3 -2,-0.3 2,-0.4 -0.994 12.2-137.5-139.5 149.5 -7.7 -11.2 18.3 61 1060 A G E +bD 7 296B 0 -55,-2.0 -53,-2.6 -2,-0.3 2,-0.3 -0.883 34.8 168.8 -93.9 137.5 -8.2 -7.6 17.5 62 1061 A S E - D 0 295B 0 233,-2.2 233,-2.8 -2,-0.4 4,-0.1 -0.967 37.9-171.9-151.2 135.3 -5.2 -5.4 18.4 63 1062 A D S S+ 0 0 4 -2,-0.3 2,-0.5 231,-0.3 230,-0.1 0.244 80.1 82.3-101.8 8.8 -4.0 -1.8 17.8 64 1063 A S S S- 0 0 0 86,-0.1 83,-0.1 231,-0.1 -56,-0.1 -0.954 86.1-123.0-105.0 127.7 -0.7 -2.8 19.4 65 1064 A K - 0 0 26 -2,-0.5 2,-0.3 1,-0.1 -2,-0.1 -0.333 30.2 -99.4 -64.3 149.8 1.8 -4.7 17.2 66 1065 A L - 0 0 3 199,-0.1 -1,-0.1 -4,-0.1 2,-0.1 -0.552 46.0-129.8 -63.1 128.5 3.1 -8.1 18.2 67 1066 A S > - 0 0 51 -2,-0.3 4,-2.7 1,-0.1 5,-0.2 -0.295 20.8-103.3 -78.6 170.9 6.5 -7.5 19.7 68 1067 A A H > S+ 0 0 81 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.903 124.3 47.5 -58.2 -41.9 9.7 -9.3 18.8 69 1068 A T H > S+ 0 0 99 2,-0.2 4,-2.5 1,-0.2 5,-0.3 0.898 110.2 51.3 -69.3 -42.5 9.4 -11.5 21.9 70 1069 A E H > S+ 0 0 45 1,-0.2 4,-2.1 2,-0.2 5,-0.2 0.948 114.0 45.3 -56.5 -48.9 5.7 -12.2 21.3 71 1070 A L H X S+ 0 0 28 -4,-2.7 4,-2.4 1,-0.2 -2,-0.2 0.931 114.4 46.2 -63.4 -46.9 6.5 -13.4 17.8 72 1071 A S H X S+ 0 0 67 -4,-2.5 4,-2.0 -5,-0.2 5,-0.2 0.898 111.6 51.1 -68.1 -36.3 9.6 -15.5 18.6 73 1072 A T H X S+ 0 0 76 -4,-2.5 4,-2.7 1,-0.2 5,-0.4 0.918 112.3 46.3 -64.5 -44.7 7.9 -17.2 21.6 74 1073 A Y H X>S+ 0 0 5 -4,-2.1 5,-2.5 -5,-0.3 4,-2.3 0.923 110.5 54.4 -64.2 -43.0 4.9 -18.2 19.4 75 1074 A A H <5S+ 0 0 41 -4,-2.4 -2,-0.2 3,-0.2 -1,-0.2 0.885 116.8 36.2 -59.6 -39.1 7.2 -19.4 16.6 76 1075 A S H <5S+ 0 0 92 -4,-2.0 -2,-0.2 -5,-0.2 -1,-0.2 0.897 127.8 32.2 -83.4 -37.7 9.1 -21.7 18.9 77 1076 A A H <5S+ 0 0 61 -4,-2.7 -3,-0.2 -5,-0.2 -2,-0.2 0.837 133.9 14.0 -87.2 -36.5 6.3 -22.9 21.2 78 1077 A K T >X5S+ 0 0 59 -4,-2.3 4,-2.9 -5,-0.4 3,-1.3 0.765 104.5 75.1-113.4 -42.9 3.1 -22.9 19.0 79 1078 A Q H 3> - 0 0 24 -2,-0.4 4,-2.4 120,-0.2 5,-0.2 -0.472 33.7-109.4 -67.9 159.2 -1.1 23.1 18.3 111 1110 A V H > S+ 0 0 33 120,-0.4 4,-2.7 1,-0.2 5,-0.2 0.926 122.1 51.8 -58.4 -40.6 1.1 20.0 18.3 112 1111 A Q H > S+ 0 0 67 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.893 107.8 50.9 -66.6 -34.5 3.3 21.6 20.9 113 1112 A E H > S+ 0 0 21 2,-0.2 4,-2.5 1,-0.2 -1,-0.2 0.912 108.9 51.7 -65.8 -42.4 0.3 22.4 23.1 114 1113 A L H X S+ 0 0 0 -4,-2.4 4,-2.4 2,-0.2 -2,-0.2 0.948 110.0 49.9 -54.1 -50.3 -0.8 18.7 22.8 115 1114 A a H X S+ 0 0 0 -4,-2.7 4,-1.4 1,-0.2 6,-0.2 0.909 111.5 48.9 -53.6 -46.4 2.7 17.7 23.9 116 1115 A G H X>S+ 0 0 0 -4,-2.2 6,-2.1 2,-0.2 4,-0.8 0.833 109.1 51.5 -67.5 -35.4 2.6 20.1 26.8 117 1116 A V H ><5S+ 0 0 1 -4,-2.5 3,-0.7 1,-0.2 -1,-0.2 0.948 114.4 43.0 -63.7 -46.8 -0.8 18.9 28.0 118 1117 A F H 3<5S+ 0 0 1 -4,-2.4 -2,-0.2 1,-0.2 -1,-0.2 0.677 115.6 48.3 -78.6 -14.9 0.2 15.2 28.0 119 1118 A S H 3<5S- 0 0 14 -4,-1.4 -1,-0.2 -5,-0.2 -2,-0.2 0.499 112.8-117.7 -89.4 -15.7 3.6 15.9 29.6 120 1119 A G T <<5S+ 0 0 19 -4,-0.8 -3,-0.2 -3,-0.7 -4,-0.1 0.299 85.4 115.8 88.8 -2.4 2.0 18.1 32.3 121 1120 A R S S-M 136 0G 49 12,-0.3 3,-1.3 1,-0.1 4,-0.1 -0.972 75.1-129.8-132.4 149.4 -4.4 25.0 32.8 125 1124 A W G > S+ 0 0 0 10,-3.4 3,-1.5 -2,-0.3 8,-0.3 0.800 109.4 67.1 -68.7 -26.3 -7.0 25.8 30.1 126 1125 A D G 3 S+ 0 0 97 9,-0.4 -1,-0.3 1,-0.2 4,-0.2 0.757 91.2 64.8 -54.8 -30.1 -5.6 29.4 30.1 127 1126 A G G < S+ 0 0 35 -3,-1.3 2,-0.6 2,-0.1 -1,-0.2 0.431 83.6 80.5 -83.1 -0.4 -2.4 27.8 28.7 128 1127 A I S X S- 0 0 1 -3,-1.5 3,-1.4 5,-0.2 5,-0.2 -0.943 92.1-120.4-100.2 117.6 -4.1 26.6 25.4 129 1128 A S T 3 S+ 0 0 50 -2,-0.6 -21,-0.4 1,-0.2 -2,-0.1 -0.276 87.8 5.9 -67.9 143.5 -4.2 29.7 23.2 130 1129 A G T 3 S+ 0 0 73 -4,-0.2 -1,-0.2 1,-0.1 -4,-0.1 0.686 88.5 130.6 68.1 16.5 -7.6 31.0 22.1 131 1130 A S < - 0 0 6 -3,-1.4 -2,-0.1 -6,-0.3 -26,-0.1 0.656 57.5-144.4 -77.6 -23.4 -9.4 28.4 24.3 132 1131 A G + 0 0 74 1,-0.2 2,-0.3 -4,-0.2 -28,-0.1 0.502 66.2 109.1 67.6 9.2 -11.9 30.8 25.9 133 1132 A R - 0 0 11 -8,-0.3 2,-0.3 -5,-0.2 -1,-0.2 -0.825 47.7-169.4-125.7 149.0 -11.4 28.6 29.0 134 1133 A T + 0 0 92 -2,-0.3 69,-0.0 -9,-0.1 -10,-0.0 -0.880 39.8 51.1-129.9 165.9 -9.8 28.8 32.3 135 1134 A G S S- 0 0 22 -2,-0.3 -10,-3.4 2,-0.0 -9,-0.4 -0.408 83.7 -25.3 99.5-177.6 -8.9 26.6 35.2 136 1135 A P B -M 124 0G 92 0, 0.0 2,-0.5 0, 0.0 -12,-0.3 -0.281 46.3-140.3 -77.2 150.1 -7.1 23.3 35.7 137 1136 A I - 0 0 13 -14,-2.3 2,-0.5 -17,-0.1 67,-0.2 -0.944 12.0-164.3-101.4 131.1 -6.6 20.4 33.2 138 1137 A V E -j 204 0E 34 65,-1.9 67,-2.1 -2,-0.5 2,-0.5 -0.981 13.1-144.5-111.3 123.2 -6.9 16.8 34.4 139 1138 A V E -j 205 0E 5 -2,-0.5 47,-2.6 44,-0.2 2,-0.4 -0.788 9.0-159.1 -87.9 132.3 -5.5 14.2 32.0 140 1139 A V E +n 186 0H 0 65,-2.7 67,-0.4 -2,-0.5 2,-0.3 -0.891 19.0 172.4-107.6 137.0 -7.3 10.8 31.8 141 1140 A Y E -n 187 0H 35 45,-2.3 47,-2.1 -2,-0.4 2,-0.4 -0.923 37.6 -85.2-142.0 166.2 -5.3 7.8 30.4 142 1141 A R E -n 188 0H 8 -2,-0.3 31,-0.5 45,-0.2 32,-0.5 -0.624 25.8-158.2 -81.5 126.5 -5.7 4.1 30.0 143 1142 A S S S+ 0 0 57 45,-2.8 46,-0.1 -2,-0.4 -1,-0.1 0.766 71.1 51.0 -67.0 -31.0 -4.7 2.0 33.0 144 1143 A E S S- 0 0 30 44,-0.4 2,-0.8 1,-0.1 29,-0.3 -0.325 107.0 -63.9-109.3-178.4 -4.0 -1.2 31.0 145 1144 A S + 0 0 40 27,-0.1 -111,-2.1 -2,-0.1 -110,-0.5 -0.607 66.9 179.9 -76.2 108.7 -2.0 -2.4 28.0 146 1145 A S > - 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0 0 141 -2,-0.5 -9,-0.1 -7,-0.2 -7,-0.0 -0.600 15.2-127.3 -83.6 149.0 -6.3 26.4 12.0 239 1238 A G - 0 0 6 -2,-0.3 2,-0.3 -11,-0.1 -9,-0.3 -0.177 26.1-132.3 -78.2-177.5 -6.1 22.8 13.0 240 1239 A V B -L 229 0F 52 -11,-1.8 -11,-2.3 47,-0.2 -9,-0.1 -0.852 19.4 -91.6-134.6 174.9 -8.8 20.3 11.8 241 1240 A S - 0 0 10 -2,-0.3 -20,-0.1 -13,-0.2 -13,-0.1 -0.345 30.3-113.5 -85.6 165.2 -10.9 17.6 13.4 242 1241 A P + 0 0 0 0, 0.0 -148,-0.3 0, 0.0 -21,-0.1 0.206 63.8 142.2 -88.2 19.5 -10.2 13.8 13.7 243 1242 A A > - 0 0 16 -23,-0.2 3,-1.9 1,-0.1 4,-0.3 -0.270 65.4-114.4 -52.0 145.3 -13.1 12.9 11.3 244 1243 A A G >> S+ 0 0 22 1,-0.3 3,-1.9 2,-0.2 4,-1.4 0.847 114.7 64.2 -54.5 -37.1 -12.1 9.9 9.1 245 1244 A A G 34 S+ 0 0 78 1,-0.3 4,-0.4 2,-0.2 -1,-0.3 0.754 96.9 58.1 -59.7 -23.2 -12.2 12.1 6.1 246 1245 A N G <4 S+ 0 0 55 -3,-1.9 42,-2.5 1,-0.2 -1,-0.3 0.538 116.2 32.3 -88.2 -5.3 -9.3 14.1 7.5 247 1246 A V T <> S+ 0 0 1 -3,-1.9 4,-2.3 -4,-0.3 5,-0.2 0.414 94.3 90.5-119.8 -5.4 -7.0 11.0 7.7 248 1247 A S H X S+ 0 0 52 -4,-1.4 4,-2.3 1,-0.2 -2,-0.1 0.871 84.4 52.3 -69.3 -34.2 -8.3 9.0 4.7 249 1248 A A H > S+ 0 0 83 -4,-0.4 4,-0.9 1,-0.2 -1,-0.2 0.935 111.9 46.6 -60.9 -47.0 -5.8 10.5 2.2 250 1249 A A H >4 S+ 0 0 23 2,-0.2 3,-0.7 1,-0.2 4,-0.3 0.907 110.7 51.7 -65.0 -40.9 -2.8 9.7 4.4 251 1250 A I H >< S+ 0 0 1 -4,-2.3 3,-1.6 1,-0.2 -1,-0.2 0.929 108.3 53.9 -59.3 -40.1 -4.1 6.1 5.1 252 1251 A G H 3< S+ 0 0 43 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.674 101.9 58.1 -67.7 -21.3 -4.4 5.6 1.4 253 1252 A A T << S+ 0 0 77 -4,-0.9 -1,-0.3 -3,-0.7 -2,-0.2 0.419 78.1 110.5 -85.9 -3.9 -0.8 6.7 0.8 254 1253 A V S < S- 0 0 6 -3,-1.6 -3,-0.0 -4,-0.3 -4,-0.0 -0.603 72.0-122.6 -76.6 126.6 0.6 3.9 3.1 255 1254 A P - 0 0 73 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 -0.274 23.9-103.8 -70.9 152.8 2.4 1.3 0.9 256 1255 A V - 0 0 51 1,-0.2 3,-0.1 14,-0.0 85,-0.1 -0.315 55.2 -74.7 -64.8 158.6 1.5 -2.3 0.9 257 1256 A P - 0 0 7 0, 0.0 -1,-0.2 0, 0.0 5,-0.1 -0.260 60.7 -95.7 -59.8 139.5 3.7 -4.8 2.8 258 1257 A A > - 0 0 52 9,-0.3 3,-2.0 1,-0.1 4,-0.4 -0.337 32.1-131.5 -60.9 128.5 7.0 -5.4 0.9 259 1258 A A G > S+ 0 0 69 1,-0.3 3,-1.3 2,-0.2 4,-0.2 0.817 102.7 50.4 -50.7 -47.8 6.7 -8.6 -1.2 260 1259 A A G 3 S+ 0 0 97 1,-0.2 -1,-0.3 2,-0.1 3,-0.2 0.638 112.3 49.1 -72.3 -10.4 9.9 -10.3 -0.1 261 1260 A D G X S+ 0 0 88 -3,-2.0 3,-2.3 1,-0.1 6,-0.3 0.357 74.4 109.7-106.7 2.8 9.1 -9.8 3.6 262 1261 A R T < + 0 0 62 -3,-1.3 -1,-0.1 -4,-0.4 -2,-0.1 0.675 67.9 65.8 -66.0 -16.5 5.5 -11.1 3.6 263 1262 A S T 3 S+ 0 0 78 -3,-0.2 -1,-0.3 -4,-0.2 -2,-0.1 0.585 88.6 81.1 -78.4 -6.2 6.3 -14.2 5.6 264 1263 A N S X S- 0 0 77 -3,-2.3 3,-1.6 1,-0.1 4,-0.4 -0.864 72.1-154.0 -96.9 110.8 7.2 -11.9 8.5 265 1264 A P G > S+ 0 0 21 0, 0.0 3,-1.2 0, 0.0 4,-0.4 0.808 92.8 63.6 -55.6 -30.7 4.0 -10.9 10.4 266 1265 A D G > S+ 0 0 66 1,-0.2 3,-1.0 2,-0.2 -4,-0.1 0.846 93.5 63.4 -62.2 -29.1 5.7 -7.6 11.6 267 1266 A A G < S+ 0 0 31 -3,-1.6 -9,-0.3 -6,-0.3 -1,-0.2 0.656 93.8 63.2 -68.2 -17.9 6.0 -6.5 7.9 268 1267 A W G < S+ 0 0 1 -3,-1.2 -1,-0.2 -4,-0.4 -2,-0.2 0.677 88.1 71.5 -82.7 -23.3 2.2 -6.4 7.5 269 1268 A V S < S- 0 0 6 -3,-1.0 2,-0.2 -4,-0.4 -1,-0.1 -0.850 73.4-149.0-100.2 109.6 1.4 -3.7 10.0 270 1269 A P - 0 0 24 0, 0.0 23,-0.4 0, 0.0 2,-0.4 -0.515 14.4-164.4 -72.4 143.2 2.4 -0.2 8.9 271 1270 A V - 0 0 20 8,-0.4 10,-2.6 -2,-0.2 2,-0.2 -0.958 13.6-134.8-124.9 147.6 3.4 2.2 11.7 272 1271 A F E +q 281 0K 8 -2,-0.4 -114,-0.0 8,-0.2 11,-0.0 -0.601 40.8 139.1 -87.9 159.3 3.8 6.0 11.6 273 1272 A G E -q 282 0K 4 8,-2.2 10,-0.7 -2,-0.2 4,-0.1 -0.913 45.5 -14.0-176.1-164.8 6.8 7.5 13.3 274 1273 A P S > S- 0 0 45 0, 0.0 3,-0.7 0, 0.0 6,-0.2 -0.184 72.5 -92.1 -60.5 151.3 9.5 10.2 13.1 275 1274 A D T 3 S+ 0 0 87 -117,-0.3 3,-0.1 1,-0.2 6,-0.0 -0.149 102.9 13.9 -55.5 151.2 10.3 12.0 10.0 276 1275 A N T 3 S+ 0 0 172 1,-0.2 2,-0.5 4,-0.0 -1,-0.2 0.807 92.0 130.8 50.2 43.2 12.9 10.9 7.5 277 1276 A T X - 0 0 70 -3,-0.7 3,-1.4 3,-0.2 -1,-0.2 -0.969 55.3-131.2-129.6 113.0 13.2 7.4 9.1 278 1277 A A T 3 S+ 0 0 105 -2,-0.5 3,-0.1 1,-0.2 -3,-0.0 -0.317 89.2 35.5 -61.8 143.8 13.0 4.3 7.0 279 1278 A G T 3 S+ 0 0 76 1,-0.2 -8,-0.4 -6,-0.0 2,-0.3 0.232 108.7 67.9 99.9 -14.5 10.6 1.6 8.1 280 1279 A V S < S- 0 0 33 -3,-1.4 -3,-0.2 -6,-0.2 -8,-0.2 -0.950 81.3-119.7-130.1 150.7 7.9 4.0 9.5 281 1280 A Q E -q 272 0K 60 -10,-2.6 -8,-2.2 -2,-0.3 2,-0.1 -0.739 32.4-117.1 -84.7 140.2 5.6 6.4 7.6 282 1281 A P E -q 273 0K 65 0, 0.0 3,-0.1 0, 0.0 -7,-0.1 -0.431 36.8 -98.2 -71.7 150.0 6.0 10.1 8.5 283 1282 A Y - 0 0 6 -10,-0.7 7,-0.1 1,-0.1 2,-0.0 -0.397 53.0 -94.8 -62.9 144.9 2.9 11.7 10.0 284 1283 A P - 0 0 26 0, 0.0 -1,-0.1 0, 0.0 -34,-0.0 -0.319 20.4-149.2 -70.5 146.3 1.0 13.6 7.3 285 1284 A T S S+ 0 0 154 -3,-0.1 2,-0.3 3,-0.0 -2,-0.1 0.582 82.9 49.8 -85.0 -20.5 1.6 17.3 6.8 286 1285 A S S S+ 0 0 87 2,-0.1 -36,-0.1 3,-0.0 2,-0.0 -0.780 103.2 12.5-113.9 167.5 -2.0 17.9 5.6 287 1286 A G S S- 0 0 43 -2,-0.3 -40,-0.2 -38,-0.0 -47,-0.2 -0.285 116.4 -17.9 62.8-158.3 -5.3 16.9 7.2 288 1287 A Y - 0 0 0 -42,-2.5 -2,-0.1 -45,-0.2 -58,-0.1 -0.697 62.0-150.4 -85.0 135.9 -5.5 15.6 10.7 289 1288 A P + 0 0 13 0, 0.0 2,-0.7 0, 0.0 -1,-0.1 0.667 68.6 78.3 -87.5 -22.5 -2.0 14.4 12.0 290 1289 A I + 0 0 0 -195,-0.2 -195,-1.8 -7,-0.1 2,-0.3 -0.822 62.9 121.6 -99.2 112.9 -2.7 11.6 14.5 291 1290 A L E + E 0 94B 1 -2,-0.7 2,-0.3 -197,-0.3 -197,-0.2 -0.953 18.2 146.0-155.7 170.4 -3.5 8.3 12.9 292 1291 A G E - E 0 93B 3 -199,-2.3 -199,-2.7 -2,-0.3 2,-0.3 -0.952 41.8 -71.1 175.9-161.7 -2.5 4.6 12.5 293 1292 A F E - E 0 92B 6 -23,-0.4 2,-0.4 -2,-0.3 -201,-0.2 -0.883 20.5-149.9-116.3 148.9 -3.9 1.1 11.9 294 1293 A T E - E 0 91B 0 -203,-2.1 -204,-3.2 -2,-0.3 -203,-1.4 -0.929 31.9-154.2-112.3 148.1 -5.8 -1.4 14.0 295 1294 A N E -DE 62 89B 2 -233,-2.8 -233,-2.2 -2,-0.4 2,-0.3 -0.679 18.1-129.5-128.6 163.6 -5.1 -5.1 13.2 296 1295 A L E -DE 61 88B 0 -208,-3.2 -208,-2.3 -2,-0.2 2,-0.4 -0.899 14.1-160.8-109.7 147.4 -6.3 -8.7 13.2 297 1296 A I E +DE 60 87B 0 -237,-2.3 -237,-2.4 -2,-0.3 2,-0.2 -0.993 26.0 152.9-129.3 120.1 -4.3 -11.7 14.5 298 1297 A F E -DE 59 86B 0 -212,-2.3 -212,-3.0 -2,-0.4 2,-0.4 -0.811 42.0-105.1-130.8 171.9 -5.4 -15.2 13.3 299 1298 A S E - E 0 85B 0 -241,-0.6 -214,-0.2 -214,-0.2 -216,-0.1 -0.829 14.3-141.5 -94.6 148.2 -3.8 -18.6 12.7 300 1299 A Q S S+ 0 0 2 -216,-2.8 59,-2.7 -2,-0.4 2,-0.4 0.807 89.4 40.7 -66.8 -30.6 -3.0 -19.8 9.2 301 1300 A b - 0 0 0 -219,-0.6 68,-2.2 -217,-0.3 2,-0.4 -0.960 57.7-175.7-131.3 141.1 -4.1 -23.3 10.3 302 1301 A Y B -r 369 0L 8 -2,-0.4 6,-0.2 66,-0.4 65,-0.1 -0.998 27.2-137.5-129.7 130.9 -7.0 -24.7 12.4 303 1302 A A S S+ 0 0 65 66,-2.8 2,-0.4 -2,-0.4 -1,-0.1 0.882 88.9 75.4 -56.6 -38.0 -7.2 -28.5 13.2 304 1303 A D S > S- 0 0 45 65,-0.5 4,-2.1 1,-0.2 5,-0.1 -0.629 72.6-149.8 -81.6 133.6 -10.9 -28.4 12.5 305 1304 A A H > S+ 0 0 70 -2,-0.4 4,-2.4 2,-0.2 5,-0.2 0.853 95.0 51.3 -66.8 -44.7 -12.1 -28.1 8.8 306 1305 A T H > S+ 0 0 83 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.946 110.7 48.5 -64.3 -43.7 -15.3 -26.2 9.5 307 1306 A Q H > S+ 0 0 2 2,-0.2 4,-2.4 1,-0.2 5,-0.2 0.927 109.7 53.0 -62.1 -41.6 -13.5 -23.6 11.6 308 1307 A T H X S+ 0 0 18 -4,-2.1 4,-2.5 1,-0.2 -1,-0.2 0.945 110.9 47.1 -54.4 -49.1 -10.9 -23.2 8.8 309 1308 A T H X S+ 0 0 74 -4,-2.4 4,-2.6 1,-0.2 -1,-0.2 0.910 110.7 51.6 -57.1 -47.4 -13.6 -22.6 6.3 310 1309 A Q H X S+ 0 0 37 -4,-2.6 4,-1.7 2,-0.2 -1,-0.2 0.861 109.4 49.9 -63.6 -37.6 -15.4 -20.1 8.5 311 1310 A V H X S+ 0 0 0 -4,-2.4 4,-2.2 2,-0.2 -1,-0.2 0.941 110.7 50.0 -66.4 -44.0 -12.1 -18.1 9.0 312 1311 A R H X S+ 0 0 71 -4,-2.5 4,-2.5 1,-0.2 -2,-0.2 0.914 107.9 53.9 -56.9 -45.1 -11.5 -18.0 5.2 313 1312 A D H X S+ 0 0 83 -4,-2.6 4,-1.4 1,-0.2 -1,-0.2 0.863 106.6 52.2 -62.7 -33.8 -15.1 -16.8 4.7 314 1313 A F H X S+ 0 0 0 -4,-1.7 4,-3.1 2,-0.2 3,-0.3 0.947 110.1 47.5 -64.5 -46.3 -14.5 -13.9 7.1 315 1314 A F H X S+ 0 0 1 -4,-2.2 4,-2.2 1,-0.2 -2,-0.2 0.897 106.3 59.1 -59.7 -38.8 -11.4 -12.9 5.2 316 1315 A T H < S+ 0 0 74 -4,-2.5 -1,-0.2 -5,-0.2 -2,-0.2 0.861 114.9 36.9 -59.0 -37.6 -13.3 -13.2 1.9 317 1316 A K H >< S+ 0 0 64 -4,-1.4 3,-1.5 -3,-0.3 8,-0.6 0.940 117.0 47.2 -74.9 -56.4 -15.8 -10.5 3.3 318 1317 A H H 3< S+ 0 0 3 -4,-3.1 -3,-0.2 1,-0.3 -2,-0.2 0.786 126.1 30.8 -64.2 -28.7 -13.5 -8.2 5.2 319 1318 A Y T 3< S+ 0 0 0 -4,-2.2 -1,-0.3 -5,-0.3 27,-0.2 0.100 94.7 129.1-113.9 20.9 -11.0 -8.0 2.3 320 1319 A G < - 0 0 7 -3,-1.5 5,-0.1 1,-0.1 4,-0.1 -0.455 59.4-140.3 -78.8 149.6 -13.4 -8.5 -0.5 321 1320 A A S S+ 0 0 70 -2,-0.1 2,-0.3 2,-0.1 3,-0.2 0.845 93.7 20.0 -65.8 -37.7 -13.7 -6.3 -3.6 322 1321 A S S S+ 0 0 90 1,-0.2 3,-0.1 3,-0.0 -1,-0.0 -0.836 120.6 28.1-127.7 163.8 -17.5 -6.6 -3.3 323 1322 A N S S+ 0 0 154 -2,-0.3 -1,-0.2 1,-0.1 2,-0.1 0.922 91.3 142.9 49.6 52.7 -19.9 -7.6 -0.6 324 1323 A N - 0 0 45 -3,-0.2 3,-0.2 -4,-0.1 -6,-0.2 -0.355 65.5-103.1-114.8-170.5 -17.5 -6.3 2.0 325 1324 A N S > S+ 0 0 7 -8,-0.6 4,-2.3 1,-0.2 5,-0.2 0.264 79.8 111.5-101.2 13.1 -17.5 -4.5 5.4 326 1325 A D H > S+ 0 0 34 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.846 74.3 52.9 -63.5 -38.2 -16.5 -1.0 4.1 327 1326 A A H > S+ 0 0 75 -3,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.954 112.3 46.1 -60.9 -44.6 -19.8 0.8 4.8 328 1327 A A H > S+ 0 0 19 1,-0.2 4,-0.9 2,-0.2 -2,-0.2 0.866 108.4 57.8 -63.1 -37.8 -19.8 -0.5 8.4 329 1328 A I H ><>S+ 0 0 2 -4,-2.3 5,-2.1 1,-0.2 3,-1.1 0.952 109.5 43.7 -54.7 -52.3 -16.1 0.6 8.7 330 1329 A T H ><5S+ 0 0 74 -4,-2.3 3,-1.8 1,-0.2 -2,-0.2 0.877 107.0 60.6 -63.0 -35.5 -17.1 4.2 7.8 331 1330 A A H 3<5S+ 0 0 60 -4,-2.1 -1,-0.2 1,-0.3 -2,-0.2 0.656 103.6 50.8 -67.9 -19.8 -20.1 4.1 10.1 332 1331 A N T <<5S- 0 0 19 -3,-1.1 -1,-0.3 -4,-0.9 -2,-0.2 0.077 125.6 -98.7-106.6 24.2 -17.8 3.5 13.1 333 1332 A A T < 5S+ 0 0 2 -3,-1.8 -239,-0.5 1,-0.3 2,-0.2 0.651 83.1 123.9 74.1 26.0 -15.4 6.4 12.2 334 1333 A F < - 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