==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=1-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 16-OCT-06 2IS0 . COMPND 2 MOLECULE: BETA-SECRETASE 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.MUNSHI . 379 2 3 2 1 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 16546.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 260 68.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 18 4.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 109 28.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 47 12.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 41 10.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 27 7.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 4 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 5 2 2 2 5 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 2 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 43PA R 0 0 244 0, 0.0 174,-0.0 0, 0.0 2,-0.0 0.000 360.0 360.0 360.0 -35.0 33.6 43.3 35.7 2 44PA R - 0 0 196 174,-0.0 174,-0.3 175,-0.0 175,-0.3 0.002 360.0-133.1 -89.3-161.2 37.3 42.3 35.5 3 45PA G > + 0 0 27 172,-0.1 3,-0.8 173,-0.1 4,-0.1 -0.577 31.9 169.0-167.1 100.1 39.1 41.0 32.4 4 46PA S T 3 S+ 0 0 116 1,-0.2 3,-0.3 -2,-0.2 -1,-0.1 0.690 92.3 57.9 -80.1 -17.6 41.5 38.1 32.0 5 47PA F T > + 0 0 54 1,-0.2 3,-2.3 169,-0.1 4,-0.5 0.202 69.5 125.0 -94.6 15.1 41.1 38.5 28.2 6 48PA V G X + 0 0 94 -3,-0.8 3,-1.4 1,-0.3 -1,-0.2 0.775 62.4 62.8 -43.7 -41.2 42.3 42.1 28.3 7 1 A E G 3 S+ 0 0 131 -3,-0.3 -1,-0.3 1,-0.3 -2,-0.1 0.663 102.1 52.1 -65.5 -14.8 45.1 41.7 25.8 8 2 A M G X S+ 0 0 20 -3,-2.3 3,-1.3 160,-0.0 161,-0.8 0.546 86.1 106.5 -94.8 -10.2 42.5 40.8 23.1 9 3 A V T < S+ 0 0 33 -3,-1.4 159,-0.1 -4,-0.5 -3,-0.0 -0.454 89.0 10.2 -70.6 139.8 40.5 43.9 23.8 10 4 A D T 3 S+ 0 0 120 -2,-0.1 -1,-0.3 1,-0.1 158,-0.2 0.758 85.9 133.4 63.4 26.1 40.7 46.6 21.1 11 5 A N < + 0 0 14 -3,-1.3 12,-0.5 84,-0.1 2,-0.3 0.408 52.1 78.8 -87.5 4.0 42.6 44.2 18.8 12 6 A L E +AB 22 167A 2 155,-2.3 155,-1.1 10,-0.1 2,-0.3 -0.854 54.6 174.8-114.1 149.3 40.4 45.1 15.9 13 7 A R E -AB 21 166A 118 8,-1.9 8,-2.4 -2,-0.3 2,-0.3 -0.841 8.1-168.1-139.5 176.0 40.6 48.1 13.6 14 8 A G - 0 0 11 151,-1.3 2,-1.2 -2,-0.3 6,-0.1 -0.931 33.4-121.4-167.7 143.8 38.9 49.5 10.4 15 9 A K S S- 0 0 89 104,-0.6 105,-0.1 4,-0.4 5,-0.1 -0.267 79.7 -74.8 -85.7 49.9 39.5 52.2 7.9 16 10 A S S S- 0 0 69 -2,-1.2 289,-0.3 1,-0.1 -1,-0.1 0.983 110.0 -8.5 56.6 87.5 36.0 53.7 8.7 17 11 A G S S+ 0 0 29 287,-0.1 -1,-0.1 1,-0.0 3,-0.1 0.599 107.9 96.3 79.1 14.7 33.3 51.5 7.2 18 12 A Q S S- 0 0 63 1,-0.3 98,-0.1 101,-0.1 2,-0.1 0.273 94.9 -53.0-119.9 13.5 35.4 49.2 5.0 19 13 A G - 0 0 19 101,-0.0 2,-0.6 207,-0.0 -4,-0.4 -0.114 45.9-106.4 125.1 138.1 35.8 46.1 7.2 20 14 A Y - 0 0 8 204,-0.4 17,-2.8 17,-0.3 2,-0.3 -0.831 44.1-176.8 -95.1 124.4 37.0 45.1 10.7 21 15 A Y E -AC 13 36A 4 -8,-2.4 -8,-1.9 -2,-0.6 2,-0.3 -0.877 18.0-155.0-125.8 157.4 40.3 43.4 10.6 22 16 A V E -AC 12 35A 2 13,-2.9 13,-3.2 -2,-0.3 2,-0.3 -0.934 30.4-106.6-126.8 147.4 42.7 41.7 13.1 23 17 A E E + C 0 34A 61 -12,-0.5 2,-0.4 -2,-0.3 72,-0.4 -0.583 38.2 178.7 -75.7 134.7 46.4 41.2 12.8 24 18 A M E - C 0 33A 0 9,-2.8 9,-2.9 -2,-0.3 2,-0.5 -0.999 15.5-151.5-135.8 134.5 47.5 37.7 12.0 25 19 A T E -DC 92 32A 25 67,-2.1 67,-2.0 -2,-0.4 2,-0.3 -0.942 18.6-177.4-113.4 123.5 51.1 36.6 11.5 26 20 A V E > +DC 91 31A 1 5,-2.9 5,-0.9 -2,-0.5 65,-0.2 -0.830 36.7 11.8-118.7 156.1 51.9 33.7 9.3 27 21 A G T 5S- 0 0 9 63,-2.1 4,-0.3 -2,-0.3 36,-0.1 0.013 85.8 -49.7 76.5 178.2 55.0 31.8 8.3 28 22 A S T 5S+ 0 0 27 2,-0.2 36,-2.8 3,-0.0 37,-0.4 -0.974 123.0 32.6-143.3 123.0 58.6 31.7 9.5 29 23 A P T 5S- 0 0 92 0, 0.0 36,-0.1 0, 0.0 -3,-0.1 0.598 123.1 -84.7 -63.6 168.4 60.1 34.1 9.9 30 24 A P T 5 - 0 0 103 0, 0.0 2,-0.4 0, 0.0 -3,-0.2 -0.093 42.8-174.3 -49.7 132.8 57.0 36.1 11.0 31 25 A Q E < -C 26 0A 26 -5,-0.9 -5,-2.9 -4,-0.3 2,-0.4 -0.914 11.9-159.8-131.8 103.2 54.8 37.8 8.3 32 26 A T E +C 25 0A 44 -2,-0.4 2,-0.3 -7,-0.3 -7,-0.3 -0.702 14.7 173.0 -91.0 134.5 52.1 40.0 9.8 33 27 A L E -C 24 0A 4 -9,-2.9 -9,-2.8 -2,-0.4 2,-0.7 -0.940 36.5-113.5-136.4 156.0 49.0 40.9 7.8 34 28 A N E -C 23 0A 4 -2,-0.3 88,-3.1 -11,-0.2 89,-0.7 -0.841 39.1-163.3 -92.4 118.6 45.7 42.7 8.5 35 29 A I E -Ce 22 123A 0 -13,-3.2 -13,-2.9 -2,-0.7 89,-0.2 -0.912 18.5-121.7-113.8 127.4 43.0 40.1 8.2 36 30 A L E -Ce 21 124A 8 87,-2.8 89,-3.4 -2,-0.5 2,-0.8 -0.419 23.1-131.9 -64.9 125.0 39.3 40.7 7.7 37 31 A V E + e 0 125A 1 -17,-2.8 2,-0.5 -2,-0.2 -17,-0.3 -0.718 36.9 173.7 -80.8 112.2 37.2 39.1 10.5 38 32 A D E > + e 0 126A 11 87,-2.0 89,-3.1 -2,-0.8 3,-0.6 -0.942 26.7 177.7-131.1 111.3 34.4 37.4 8.5 39 33 A T T 3 S+ 0 0 0 -2,-0.5 155,-0.5 87,-0.2 183,-0.2 0.353 75.9 74.8 -90.0 4.8 31.8 35.1 10.1 40 34 A G T 3 S+ 0 0 11 153,-0.1 2,-0.2 88,-0.1 -1,-0.2 0.472 99.6 31.8 -95.9 -3.6 30.0 34.6 6.7 41 35 A S < - 0 0 10 -3,-0.6 87,-3.3 84,-0.1 92,-0.1 -0.824 65.4-135.9-140.7-179.4 32.6 32.2 5.1 42 36 A S + 0 0 2 90,-0.5 2,-0.4 -2,-0.2 100,-0.3 0.302 64.1 98.7-130.1 13.5 35.0 29.5 6.1 43 37 A N - 0 0 5 98,-0.1 83,-1.7 89,-0.1 2,-0.7 -0.835 57.3-144.9-106.1 141.5 38.3 30.0 4.3 44 38 A F E +F 125 0A 8 -2,-0.4 62,-2.1 81,-0.2 2,-0.4 -0.927 36.9 166.3 -98.9 115.8 41.4 31.7 5.6 45 39 A A E -Fg 124 106A 0 79,-2.4 79,-3.4 -2,-0.7 2,-0.4 -0.998 17.0-172.5-137.4 139.5 42.9 33.5 2.6 46 40 A V E -Fg 123 107A 0 60,-2.3 62,-2.9 -2,-0.4 77,-0.3 -0.985 37.0 -99.7-134.3 141.2 45.5 36.2 2.2 47 41 A G E + g 0 108A 0 75,-3.3 11,-3.0 -2,-0.4 62,-0.2 -0.360 38.6 178.3 -55.0 131.1 46.7 38.3 -0.7 48 42 A A + 0 0 10 60,-3.5 12,-0.2 9,-0.2 61,-0.2 0.190 59.8 46.1-122.6 12.4 49.9 36.5 -1.9 49 43 A A S S- 0 0 28 59,-0.5 9,-0.1 7,-0.1 7,-0.1 -0.979 98.7 -76.1-150.1 155.5 50.8 38.8 -4.8 50 44 A P + 0 0 98 0, 0.0 -2,-0.1 0, 0.0 5,-0.1 -0.213 49.5 175.0 -57.0 142.5 51.0 42.5 -5.4 51 45 A H > - 0 0 52 3,-0.4 3,-2.1 1,-0.1 59,-0.0 -0.985 41.3-118.8-148.5 142.7 47.7 44.3 -5.8 52 46 A P T 3 S+ 0 0 117 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 0.841 117.6 44.8 -50.2 -38.1 46.9 48.1 -6.2 53 47 A F T 3 S+ 0 0 77 64,-0.1 2,-0.5 -3,-0.0 67,-0.3 0.403 98.4 89.6 -89.7 0.6 44.8 48.0 -3.0 54 48 A L < - 0 0 17 -3,-2.1 -3,-0.4 1,-0.1 3,-0.1 -0.885 48.0-174.7-106.6 127.0 47.4 45.9 -1.1 55 49 A H S S+ 0 0 132 -2,-0.5 2,-0.3 1,-0.3 -1,-0.1 0.773 79.8 2.6 -82.8 -30.3 50.1 47.6 1.0 56 50 A R - 0 0 94 -7,-0.1 2,-0.3 -6,-0.0 -1,-0.3 -0.978 68.0-168.4-152.3 161.6 51.7 44.2 1.8 57 51 A Y - 0 0 77 -2,-0.3 2,-0.3 -9,-0.1 -9,-0.2 -0.965 34.6 -79.4-152.3 166.6 51.2 40.5 1.0 58 52 A Y - 0 0 1 -11,-3.0 2,-0.7 -2,-0.3 -31,-0.0 -0.527 34.0-163.9 -71.9 123.7 52.1 36.9 1.9 59 53 A Q > - 0 0 67 -2,-0.3 3,-1.6 1,-0.1 4,-0.4 -0.830 4.9-174.1-112.8 91.0 55.4 35.8 0.4 60 54 A R G > S+ 0 0 49 -2,-0.7 3,-1.1 1,-0.3 6,-0.3 0.755 78.9 64.1 -55.8 -31.9 55.5 32.0 0.6 61 55 A Q G 3 S+ 0 0 150 1,-0.2 -1,-0.3 3,-0.0 -2,-0.0 0.748 100.7 53.3 -67.4 -21.5 59.1 31.7 -0.6 62 56 A L G < S+ 0 0 94 -3,-1.6 2,-0.7 1,-0.1 -1,-0.2 0.530 92.7 83.8 -89.3 -7.0 60.3 33.5 2.5 63 57 A S X - 0 0 7 -3,-1.1 3,-1.1 -4,-0.4 -36,-0.1 -0.868 58.0-168.0-100.9 111.5 58.4 31.2 4.9 64 58 A S T 3 S+ 0 0 106 -36,-2.8 -1,-0.1 -2,-0.7 -4,-0.0 0.693 87.9 54.3 -69.6 -18.8 60.5 28.0 5.6 65 59 A T T 3 S+ 0 0 34 -37,-0.4 -1,-0.2 -36,-0.1 2,-0.2 0.446 78.8 119.5 -94.9 -2.3 57.4 26.4 7.2 66 60 A Y < - 0 0 41 -3,-1.1 2,-0.5 -6,-0.3 23,-0.2 -0.452 45.0-163.8 -68.0 133.9 55.1 26.8 4.3 67 61 A R E -H 88 0A 149 21,-2.8 21,-2.2 -2,-0.2 2,-0.3 -0.981 13.6-135.8-123.3 122.8 53.7 23.6 2.8 68 62 A D E -H 87 0A 85 -2,-0.5 19,-0.3 19,-0.2 18,-0.0 -0.592 7.8-162.7 -78.5 130.0 52.1 23.5 -0.7 69 63 A L E - 0 0 72 17,-2.4 18,-0.2 -2,-0.3 -1,-0.1 0.497 32.1-132.5 -88.5 -3.6 48.9 21.5 -0.9 70 64 A R E + 0 0 224 16,-0.5 2,-0.3 1,-0.2 17,-0.1 0.926 69.4 106.3 52.6 51.0 49.2 21.4 -4.7 71 65 A K E - 0 0 87 15,-0.5 15,-3.2 2,-0.0 -2,-0.2 -0.958 60.9-134.9-158.2 136.9 45.6 22.4 -5.2 72 66 A G E -H 85 0A 49 -2,-0.3 2,-0.3 13,-0.2 13,-0.2 -0.458 15.4-156.5 -90.2 166.4 43.9 25.5 -6.4 73 67 A V E -H 84 0A 10 11,-2.1 11,-2.4 -2,-0.1 2,-0.4 -0.997 6.7-167.6-145.8 139.6 40.8 27.2 -4.9 74 68 A Y E -H 83 0A 141 -2,-0.3 9,-0.2 9,-0.2 -2,-0.0 -0.998 7.5-176.1-128.7 130.2 38.3 29.6 -6.3 75 69 A V E -H 82 0A 5 7,-2.6 7,-1.8 -2,-0.4 2,-0.4 -0.933 3.0-175.1-134.1 111.7 35.8 31.5 -4.0 76 70 A P E -H 81 0A 47 0, 0.0 5,-0.2 0, 0.0 2,-0.2 -0.857 7.7-174.6-105.2 141.0 33.0 33.7 -5.3 77 71 A Y - 0 0 65 3,-2.6 3,-0.2 -2,-0.4 -36,-0.0 -0.632 47.9 -91.2-119.0-179.1 30.8 35.7 -2.9 78 72 A T S S+ 0 0 107 1,-0.3 2,-0.5 -2,-0.2 3,-0.0 0.904 125.0 32.1 -58.9 -38.6 27.8 37.9 -3.4 79 73 A Q S S- 0 0 135 1,-0.0 -1,-0.3 35,-0.0 34,-0.0 -0.976 124.9 -17.2-123.7 117.7 30.4 40.7 -3.7 80 74 A G - 0 0 17 -2,-0.5 -3,-2.6 -3,-0.2 2,-0.3 0.045 58.1-141.6 80.8 169.9 33.8 39.9 -5.2 81 75 A A E -HI 76 112A 13 31,-1.6 31,-2.7 -5,-0.2 2,-0.3 -0.972 10.5-166.4-165.4 156.2 35.7 36.8 -5.9 82 76 A W E -HI 75 111A 2 -7,-1.8 -7,-2.6 -2,-0.3 2,-0.4 -0.972 9.8-148.4-148.8 164.6 39.3 35.4 -5.7 83 77 A A E +HI 74 110A 33 27,-2.9 26,-1.8 -2,-0.3 27,-1.6 -0.989 28.9 146.1-134.7 141.5 41.5 32.6 -6.8 84 78 A G E -HI 73 108A 7 -11,-2.4 -11,-2.1 -2,-0.4 2,-0.4 -0.880 43.3 -88.5-156.8-170.2 44.6 31.1 -5.0 85 79 A E E -HI 72 107A 77 22,-1.6 22,-2.8 -2,-0.3 -13,-0.2 -0.925 37.7-126.6-115.8 137.1 46.7 28.2 -4.2 86 80 A L E + I 0 106A 0 -15,-3.2 -17,-2.4 -2,-0.4 -16,-0.5 -0.572 45.3 129.8 -85.7 146.6 46.1 26.0 -1.1 87 81 A G E -HI 68 105A 0 18,-1.4 18,-2.9 -19,-0.3 2,-0.3 -0.920 43.2-114.6-168.7-172.2 48.8 25.3 1.4 88 82 A T E +HI 67 104A 16 -21,-2.2 -21,-2.8 -2,-0.3 2,-0.3 -0.973 30.8 158.5-141.3 154.6 49.4 25.3 5.2 89 83 A D E - I 0 103A 0 14,-1.5 14,-2.4 -2,-0.3 2,-0.3 -0.955 48.7 -73.0-164.3 169.9 51.7 27.3 7.4 90 84 A L E - I 0 102A 58 -2,-0.3 -63,-2.1 12,-0.2 2,-0.4 -0.570 49.9-169.5 -76.8 137.3 52.1 28.3 11.1 91 85 A V E +DI 26 101A 1 10,-2.8 10,-2.2 -2,-0.3 2,-0.3 -0.996 13.1 167.2-136.0 133.3 49.6 30.9 12.1 92 86 A S E -D 25 0A 30 -67,-2.0 -67,-2.1 -2,-0.4 8,-0.1 -0.877 28.6-138.8-133.8 164.7 49.3 33.1 15.3 93 87 A I > - 0 0 5 4,-0.6 3,-2.7 6,-0.5 -69,-0.2 -0.926 14.1-153.2-129.6 100.9 47.3 36.1 16.2 94 88 A P T 3 S+ 0 0 50 0, 0.0 -1,-0.1 0, 0.0 -70,-0.1 0.824 97.6 32.6 -40.1 -49.7 49.5 38.5 18.2 95 89 A H T 3 S+ 0 0 76 -72,-0.4 -84,-0.1 -84,-0.1 3,-0.1 -0.095 117.9 67.6-103.8 31.5 46.6 40.1 20.1 96 90 A G S < S- 0 0 6 -3,-2.7 -87,-0.1 1,-0.4 74,-0.0 -0.267 101.6 -20.9-124.3-148.4 44.6 36.9 20.1 97 91 A P - 0 0 10 0, 0.0 2,-1.8 0, 0.0 -4,-0.6 -0.261 64.6-114.4 -63.1 152.2 45.1 33.5 21.9 98 92 A N S S+ 0 0 169 -3,-0.1 2,-0.3 -6,-0.1 -6,-0.0 -0.503 82.6 95.3 -86.8 66.7 48.6 32.6 23.0 99 93 A V - 0 0 41 -2,-1.8 -6,-0.5 -6,-0.2 2,-0.4 -0.932 59.3-145.5-147.0 168.7 49.0 29.7 20.6 100 94 A T - 0 0 82 -2,-0.3 2,-0.3 -8,-0.1 -8,-0.2 -0.993 22.4-178.7-139.0 132.7 50.3 28.9 17.2 101 95 A V E - I 0 91A 2 -10,-2.2 -10,-2.8 -2,-0.4 2,-0.8 -0.918 33.7-115.5-132.3 158.6 48.7 26.3 14.9 102 96 A R E + I 0 90A 50 -2,-0.3 2,-0.3 -12,-0.2 -12,-0.2 -0.865 49.7 177.1 -93.0 115.2 49.3 24.9 11.4 103 97 A A E - I 0 89A 2 -14,-2.4 -14,-1.5 -2,-0.8 2,-0.3 -0.808 35.9 -99.9-121.2 161.5 46.4 26.1 9.4 104 98 A N E - I 0 88A 31 36,-0.5 2,-0.4 -2,-0.3 -16,-0.3 -0.587 41.8-171.7 -75.7 137.6 45.1 25.9 5.8 105 99 A I E - I 0 87A 2 -18,-2.9 -18,-1.4 -2,-0.3 2,-0.6 -1.000 18.0-149.4-135.7 133.0 45.9 29.1 4.0 106 100 A A E -gI 45 86A 1 -62,-2.1 -60,-2.3 -2,-0.4 2,-0.8 -0.922 16.8-144.8-102.3 117.9 44.7 30.1 0.5 107 101 A A E -gI 46 85A 1 -22,-2.8 -22,-1.6 -2,-0.6 2,-0.6 -0.767 15.5-141.4 -85.3 107.8 47.3 32.3 -1.1 108 102 A I E +gI 47 84A 4 -62,-2.9 -60,-3.5 -2,-0.8 -59,-0.5 -0.595 35.4 159.1 -75.7 115.1 45.4 34.8 -3.2 109 103 A T E + 0 0 44 -26,-1.8 2,-0.3 -2,-0.6 -25,-0.2 0.550 67.5 25.7-110.5 -12.3 47.1 35.5 -6.5 110 104 A E E + I 0 83A 136 -27,-1.6 -27,-2.9 2,-0.0 -1,-0.3 -0.989 65.9 161.1-153.1 142.2 44.2 36.9 -8.4 111 105 A S E - 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