==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=25-JUL-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 30-APR-10 3MTC . COMPND 2 MOLECULE: TYPE II INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATAS . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR L.TRESAUGUES,M.WELIN,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,R.C . 310 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14246.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 200 64.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 16 5.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 77 24.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 23 7.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 26 8.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 44 14.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 0 1 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 5 0 0 0 0 1 2 2 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 258 A M 0 0 170 0, 0.0 2,-0.4 0, 0.0 307,-0.1 0.000 360.0 360.0 360.0 157.5 67.1 58.0 64.9 2 259 A Y - 0 0 194 305,-0.4 305,-2.9 2,-0.0 2,-0.3 -0.951 360.0-160.4-119.2 141.3 63.5 57.9 63.8 3 260 A T E -A 306 0A 47 -2,-0.4 2,-0.3 303,-0.3 303,-0.2 -0.906 8.0-178.5-118.8 152.3 61.6 54.8 62.5 4 261 A Y E -A 305 0A 99 301,-2.5 301,-3.2 -2,-0.3 2,-0.5 -0.948 34.2 -97.8-140.5 158.1 58.4 54.5 60.5 5 262 A I E +A 304 0A 61 -2,-0.3 2,-0.4 299,-0.2 299,-0.2 -0.704 37.2 180.0 -81.2 123.7 56.2 51.6 59.2 6 263 A Q E -A 303 0A 73 297,-2.6 297,-2.9 -2,-0.5 2,-0.3 -0.995 25.3-125.8-122.4 132.2 56.8 50.7 55.5 7 264 A N E -A 302 0A 99 -2,-0.4 2,-0.3 295,-0.2 295,-0.2 -0.588 27.3-177.2 -82.2 132.6 54.8 47.8 53.9 8 265 A F E -A 301 0A 4 293,-2.5 293,-2.8 -2,-0.3 2,-0.6 -0.948 25.8-120.1-125.1 152.1 56.5 44.9 52.2 9 266 A R E -A 300 0A 58 -2,-0.3 30,-2.1 291,-0.2 29,-1.9 -0.826 27.5-170.8 -95.3 121.0 55.1 41.9 50.3 10 267 A F E -Ab 299 39A 0 289,-2.2 289,-2.8 -2,-0.6 2,-0.4 -0.946 7.4-158.6-111.6 127.5 56.0 38.5 51.7 11 268 A F E -Ab 298 40A 2 28,-3.0 30,-2.5 -2,-0.5 2,-0.4 -0.886 8.2-169.8-100.1 133.1 55.2 35.2 49.9 12 269 A A E -Ab 297 41A 0 285,-2.7 285,-2.1 -2,-0.4 2,-0.3 -0.996 7.8-179.9-123.4 130.8 55.1 32.1 52.0 13 270 A G E -Ab 296 42A 0 28,-2.4 30,-2.4 -2,-0.4 2,-0.4 -0.973 11.6-172.2-131.5 142.9 54.9 28.6 50.3 14 271 A T E +Ab 295 43A 0 281,-2.2 281,-2.7 -2,-0.3 2,-0.3 -0.999 9.6 171.6-133.5 138.8 54.7 25.1 51.5 15 272 A Y E - b 0 44A 0 28,-1.5 30,-1.8 -2,-0.4 2,-0.7 -0.913 24.1-154.2-151.4 113.9 55.0 21.9 49.3 16 273 A N E - b 0 45A 0 -2,-0.3 276,-0.6 28,-0.2 30,-0.2 -0.848 16.8-171.6 -84.7 115.6 55.3 18.2 50.4 17 274 A V > - 0 0 0 28,-2.4 3,-2.5 -2,-0.7 29,-0.1 0.226 28.3-129.6-102.9 12.1 57.0 16.8 47.3 18 275 A N T 3 - 0 0 40 1,-0.3 29,-0.1 27,-0.2 28,-0.1 0.782 65.9 -60.7 45.9 39.1 56.7 13.1 48.2 19 276 A G T 3 S+ 0 0 20 27,-2.7 -1,-0.3 26,-0.3 30,-0.3 0.517 101.5 136.3 75.3 7.1 60.4 12.3 47.6 20 277 A Q < - 0 0 59 -3,-2.5 -1,-0.2 26,-0.2 -3,-0.1 -0.416 56.9-119.1 -87.0 157.8 60.3 13.4 43.9 21 278 A S - 0 0 36 -2,-0.1 2,-0.2 1,-0.1 -1,-0.1 -0.633 49.5 -89.4 -79.9 152.1 62.7 15.4 41.8 22 279 A P + 0 0 35 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.496 50.8 165.8 -67.7 130.6 61.0 18.6 40.3 23 280 A K + 0 0 133 -2,-0.2 2,-0.3 2,-0.1 -2,-0.0 0.523 55.6 61.2-116.5 -17.4 59.4 17.9 36.9 24 281 A E S S- 0 0 54 1,-0.0 2,-0.2 2,-0.0 263,-0.0 -0.803 89.1 -98.8-116.7 153.6 57.2 21.0 36.4 25 282 A C > - 0 0 85 -2,-0.3 3,-0.6 1,-0.1 4,-0.1 -0.503 29.9-145.6 -63.1 135.0 57.9 24.7 36.2 26 283 A L T >> S+ 0 0 4 42,-0.4 4,-3.0 1,-0.2 3,-1.8 0.442 78.1 95.6 -91.8 1.7 57.2 26.3 39.6 27 284 A R H 3> S+ 0 0 103 1,-0.3 4,-2.2 2,-0.2 -1,-0.2 0.876 76.6 65.6 -52.5 -37.5 55.8 29.6 38.3 28 285 A L H <4 S+ 0 0 72 -3,-0.6 -1,-0.3 1,-0.2 4,-0.1 0.740 116.4 28.2 -59.4 -21.3 52.4 28.0 38.7 29 286 A W H <4 S+ 0 0 1 -3,-1.8 3,-0.3 2,-0.1 -2,-0.2 0.824 130.1 33.9 -98.1 -48.8 53.2 28.1 42.4 30 287 A L H < S+ 0 0 0 -4,-3.0 44,-0.3 1,-0.2 -3,-0.2 0.633 132.7 13.5 -95.2 -21.1 55.6 30.9 43.0 31 288 A S S < S+ 0 0 2 -4,-2.2 2,-0.9 -5,-0.3 -1,-0.2 -0.379 72.7 149.0-155.2 64.9 54.6 33.6 40.5 32 289 A N S S- 0 0 90 -3,-0.3 3,-0.1 1,-0.2 -4,-0.1 -0.838 85.8 -36.4-108.6 90.6 51.2 32.8 39.1 33 290 A G S S+ 0 0 84 -2,-0.9 2,-0.3 1,-0.2 -1,-0.2 0.856 107.5 121.5 62.0 39.9 49.4 36.1 38.3 34 291 A I - 0 0 43 3,-0.0 -1,-0.2 1,-0.0 2,-0.1 -0.904 67.7 -97.3-125.8 159.4 50.8 38.0 41.3 35 292 A Q - 0 0 124 -2,-0.3 39,-0.1 1,-0.1 -3,-0.1 -0.402 58.5 -84.0 -62.1 151.6 52.9 41.2 41.9 36 293 A A - 0 0 18 -2,-0.1 -27,-0.1 1,-0.1 -1,-0.1 -0.423 50.9-131.1 -59.1 118.0 56.6 40.6 42.4 37 294 A P - 0 0 1 0, 0.0 -27,-0.2 0, 0.0 3,-0.1 -0.393 3.6-142.1 -68.5 154.4 57.0 39.8 46.1 38 295 A D S S+ 0 0 22 -29,-1.9 59,-2.4 1,-0.3 2,-0.4 0.813 89.1 25.3 -78.6 -35.8 59.7 41.7 48.2 39 296 A V E -bC 10 96A 0 -30,-2.1 -28,-3.0 57,-0.2 2,-0.5 -0.998 67.6-157.7-135.1 135.1 60.5 38.5 50.2 40 297 A Y E -bC 11 95A 0 55,-2.4 55,-2.4 -2,-0.4 2,-0.5 -0.959 7.3-177.1-112.8 127.5 60.1 34.8 49.3 41 298 A C E -bC 12 94A 1 -30,-2.5 -28,-2.4 -2,-0.5 2,-0.5 -0.967 13.9-178.9-123.0 108.7 59.8 32.1 52.0 42 299 A V E -bC 13 93A 0 51,-2.4 51,-2.4 -2,-0.5 2,-0.4 -0.948 2.3-174.7-123.9 119.7 59.6 28.7 50.4 43 300 A G E -bC 14 92A 0 -30,-2.4 -28,-1.5 -2,-0.5 2,-0.3 -0.881 3.7-171.6-121.2 142.4 59.3 25.4 52.3 44 301 A F E -bC 15 91A 0 47,-2.6 47,-1.5 -2,-0.4 2,-0.3 -0.907 7.3-160.0-124.9 153.8 59.4 21.8 51.4 45 302 A Q E S+b 16 0A 0 -30,-1.8 -28,-2.4 -2,-0.3 -26,-0.3 -0.940 75.8 18.3-125.9 155.7 58.7 18.5 53.1 46 303 A E + 0 0 36 -2,-0.3 -27,-2.7 -30,-0.2 3,-0.2 0.845 66.0 159.0 55.3 42.2 59.8 15.0 52.0 47 304 A L S S+ 0 0 0 42,-1.7 2,-0.3 1,-0.3 42,-0.1 0.820 75.9 11.0 -57.0 -34.0 62.5 16.4 49.7 48 305 A D - 0 0 20 2,-0.1 -1,-0.3 1,-0.0 -2,-0.1 -0.902 58.5-173.2-153.9 115.5 64.3 13.0 49.8 49 306 A L + 0 0 111 -2,-0.3 -2,-0.0 -30,-0.3 -1,-0.0 0.311 47.7 123.2 -95.8 9.2 62.8 9.8 51.3 50 307 A S S > S- 0 0 37 1,-0.1 4,-1.8 -31,-0.1 5,-0.1 -0.250 70.9-123.5 -72.4 155.1 66.0 7.7 51.0 51 308 A K H > S+ 0 0 145 1,-0.2 4,-1.7 2,-0.2 -1,-0.1 0.851 113.0 59.1 -60.4 -34.7 67.7 5.9 53.9 52 309 A E H 4>S+ 0 0 89 2,-0.2 5,-1.9 1,-0.2 -1,-0.2 0.920 106.7 45.4 -63.7 -42.9 70.9 7.9 53.1 53 310 A A H >45S+ 0 0 2 1,-0.2 3,-1.8 3,-0.2 -1,-0.2 0.870 107.5 59.3 -67.9 -36.7 69.1 11.2 53.6 54 311 A F H 3<5S+ 0 0 48 -4,-1.8 67,-0.4 1,-0.3 -1,-0.2 0.862 102.2 52.9 -58.2 -38.5 67.6 9.9 56.8 55 312 A F T 3<5S- 0 0 125 -4,-1.7 -1,-0.3 -3,-0.1 -2,-0.2 0.093 127.9-101.3 -91.8 25.2 71.2 9.3 58.2 56 313 A F T < 5 + 0 0 103 -3,-1.8 -3,-0.2 1,-0.2 -2,-0.1 0.548 69.0 150.9 77.5 18.9 71.9 13.0 57.3 57 314 A H < - 0 0 116 -5,-1.9 -1,-0.2 1,-0.1 31,-0.1 -0.380 53.9 -93.6 -72.8 154.3 73.9 12.7 54.1 58 315 A D - 0 0 149 -2,-0.1 -1,-0.1 2,-0.0 3,-0.0 -0.320 43.0-156.7 -60.3 150.0 73.9 15.4 51.4 59 316 A T >> - 0 0 12 -3,-0.1 3,-1.2 1,-0.1 4,-0.5 -0.994 25.8-137.0-135.8 139.6 71.3 14.9 48.7 60 317 A P H 3> S+ 0 0 91 0, 0.0 4,-2.4 0, 0.0 5,-0.1 0.698 99.4 78.6 -68.9 -15.3 71.2 16.2 45.1 61 318 A K H 3> S+ 0 0 39 1,-0.2 4,-2.3 2,-0.2 5,-0.3 0.804 84.1 63.5 -57.6 -31.9 67.5 16.9 45.8 62 319 A E H <> S+ 0 0 61 -3,-1.2 4,-2.3 2,-0.2 -1,-0.2 0.970 109.5 35.6 -57.2 -59.2 68.6 20.0 47.7 63 320 A E H X S+ 0 0 121 -4,-0.5 4,-3.0 2,-0.2 5,-0.3 0.900 114.8 57.4 -64.3 -42.7 70.1 21.7 44.6 64 321 A E H X S+ 0 0 62 -4,-2.4 4,-2.1 1,-0.2 -2,-0.2 0.947 114.6 37.1 -53.6 -51.7 67.4 20.3 42.2 65 322 A W H X S+ 0 0 2 -4,-2.3 4,-2.4 2,-0.2 -1,-0.2 0.888 115.0 54.4 -72.1 -38.0 64.6 21.9 44.2 66 323 A F H X S+ 0 0 41 -4,-2.3 4,-2.5 -5,-0.3 -2,-0.2 0.924 110.7 46.5 -58.5 -45.6 66.6 25.1 45.0 67 324 A K H X S+ 0 0 40 -4,-3.0 4,-2.0 1,-0.2 -2,-0.2 0.934 111.0 53.1 -61.2 -44.0 67.3 25.6 41.3 68 325 A A H X S+ 0 0 10 -4,-2.1 4,-1.0 -5,-0.3 -42,-0.4 0.883 110.7 46.0 -62.3 -40.4 63.6 24.9 40.5 69 326 A V H >X S+ 0 0 0 -4,-2.4 4,-1.0 2,-0.2 3,-0.9 0.955 110.0 54.2 -64.7 -48.2 62.4 27.6 43.0 70 327 A S H 3< S+ 0 0 40 -4,-2.5 3,-0.5 1,-0.3 -2,-0.2 0.858 110.0 47.4 -54.5 -37.6 65.0 30.1 41.7 71 328 A E H 3< S+ 0 0 145 -4,-2.0 -1,-0.3 1,-0.2 -2,-0.2 0.705 110.9 52.5 -78.3 -22.3 63.6 29.6 38.2 72 329 A G H << S+ 0 0 1 -4,-1.0 -1,-0.2 -3,-0.9 -2,-0.2 0.486 82.5 110.8 -92.7 -6.1 60.0 30.0 39.3 73 330 A L S < S- 0 0 12 -4,-1.0 -42,-0.2 -3,-0.5 -46,-0.1 -0.249 89.2 -70.3 -65.4 159.4 60.4 33.3 41.2 74 331 A H > - 0 0 20 -44,-0.3 3,-1.0 1,-0.1 -1,-0.2 -0.255 41.6-138.8 -55.6 131.8 58.8 36.4 39.8 75 332 A P T 3 S+ 0 0 81 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.698 90.4 72.0 -68.3 -19.6 60.6 37.5 36.6 76 333 A D T 3 S+ 0 0 132 2,-0.0 2,-0.4 0, 0.0 -2,-0.1 0.604 97.5 47.6 -75.0 -13.8 60.5 41.3 37.3 77 334 A A S < S- 0 0 25 -3,-1.0 2,-0.5 21,-0.0 20,-0.0 -0.963 75.9-126.5-127.5 146.3 63.0 41.2 40.1 78 335 A K - 0 0 115 -2,-0.4 20,-2.7 2,-0.0 2,-0.4 -0.810 35.4-149.4 -77.4 125.0 66.5 39.8 40.6 79 336 A Y E -D 97 0A 27 -2,-0.5 2,-0.4 18,-0.2 18,-0.3 -0.859 1.3-141.8-103.0 134.5 66.2 37.8 43.9 80 337 A A E -D 96 0A 15 16,-3.5 16,-2.0 -2,-0.4 2,-0.6 -0.799 18.7-125.4 -91.5 135.0 69.1 37.4 46.3 81 338 A K E +D 95 0A 140 -2,-0.4 14,-0.2 14,-0.2 3,-0.1 -0.715 34.0 173.5 -77.6 115.9 69.5 34.0 48.0 82 339 A V E - 0 0 36 12,-2.8 2,-0.3 -2,-0.6 13,-0.2 0.887 56.3 -13.6 -92.9 -45.9 69.6 34.9 51.7 83 340 A K E -D 94 0A 86 11,-1.6 11,-2.7 2,-0.0 2,-0.4 -0.981 44.9-164.7-163.4 143.5 69.5 31.5 53.4 84 341 A L E +D 93 0A 51 -2,-0.3 2,-0.3 9,-0.2 9,-0.2 -0.986 14.3 176.3-127.2 137.4 68.9 27.8 52.9 85 342 A I E +D 92 0A 32 7,-1.9 7,-2.7 -2,-0.4 2,-0.4 -0.991 2.9 178.2-144.1 137.5 68.4 25.3 55.8 86 343 A R E -D 91 0A 38 -2,-0.3 2,-0.4 5,-0.2 5,-0.2 -1.000 19.7-173.7-142.2 135.6 67.6 21.6 55.6 87 344 A L E > S-D 90 0A 20 3,-2.6 3,-2.8 -2,-0.4 2,-0.3 -0.957 74.0 -59.6-122.7 109.6 67.0 18.7 58.0 88 345 A V T 3 S- 0 0 10 -2,-0.4 34,-0.1 1,-0.3 -34,-0.1 -0.358 126.0 -9.5 54.2-108.3 66.6 15.5 55.9 89 346 A G T 3 S+ 0 0 5 32,-0.5 -42,-1.7 -2,-0.3 2,-0.7 0.433 115.8 95.1 -98.5 2.0 63.5 16.3 53.8 90 347 A I E < + D 0 87A 2 -3,-2.8 -3,-2.6 31,-0.2 2,-0.4 -0.852 52.5 169.4 -98.4 113.7 62.5 19.5 55.5 91 348 A M E -CD 44 86A 0 -47,-1.5 -47,-2.6 -2,-0.7 2,-0.4 -0.982 17.2-169.8-131.6 136.4 64.0 22.5 53.6 92 349 A L E -CD 43 85A 2 -7,-2.7 -7,-1.9 -2,-0.4 2,-0.4 -0.995 5.4-166.4-127.1 134.0 63.4 26.2 53.9 93 350 A L E -CD 42 84A 1 -51,-2.4 -51,-2.4 -2,-0.4 2,-0.5 -0.962 2.8-163.4-120.1 136.2 64.6 28.9 51.5 94 351 A L E +CD 41 83A 5 -11,-2.7 -12,-2.8 -2,-0.4 -11,-1.6 -0.984 14.1 170.3-119.7 124.5 64.7 32.7 52.1 95 352 A Y E -CD 40 81A 3 -55,-2.4 -55,-2.4 -2,-0.5 2,-0.3 -0.958 9.6-170.0-124.6 150.3 65.1 35.1 49.1 96 353 A V E -CD 39 80A 0 -16,-2.0 -16,-3.5 -2,-0.3 -57,-0.2 -0.979 39.0 -91.4-132.6 148.7 64.8 38.9 49.1 97 354 A K E >> - D 0 79A 36 -59,-2.4 3,-1.6 -2,-0.3 4,-0.7 -0.320 43.8-115.0 -50.4 142.8 64.7 41.3 46.1 98 355 A Q G >4 S+ 0 0 102 -20,-2.7 3,-1.6 1,-0.3 4,-0.5 0.895 114.5 59.2 -51.0 -47.6 68.3 42.5 45.4 99 356 A E G 34 S+ 0 0 147 1,-0.3 -1,-0.3 -21,-0.2 3,-0.2 0.740 108.5 46.1 -56.3 -24.1 67.5 46.1 46.3 100 357 A H G X4 S+ 0 0 20 -3,-1.6 3,-1.6 -62,-0.1 -1,-0.3 0.553 86.7 91.2 -93.8 -9.5 66.4 45.0 49.8 101 358 A A G X< S+ 0 0 26 -3,-1.6 3,-1.9 -4,-0.7 -2,-0.1 0.841 76.7 62.0 -60.4 -38.1 69.4 42.7 50.6 102 359 A A G 3 S+ 0 0 93 -4,-0.5 -1,-0.3 1,-0.3 -2,-0.1 0.688 100.6 56.7 -61.5 -17.2 71.6 45.3 52.2 103 360 A Y G < S+ 0 0 113 -3,-1.6 30,-2.5 -4,-0.1 2,-0.5 0.231 84.9 98.0-100.7 13.5 68.9 45.7 54.9 104 361 A I E < +F 132 0B 27 -3,-1.9 2,-0.3 28,-0.2 28,-0.2 -0.884 49.5 154.5 -97.6 126.9 68.9 42.0 55.9 105 362 A S E +F 131 0B 52 26,-2.5 26,-3.0 -2,-0.5 -2,-0.0 -0.920 42.9 37.2-143.2 171.9 71.0 41.2 59.0 106 363 A E E - 0 0 79 -2,-0.3 2,-0.5 24,-0.2 -1,-0.1 0.865 66.9-177.3 53.3 46.7 71.4 38.7 61.9 107 364 A V E + 0 0 39 23,-0.2 2,-0.3 -3,-0.1 23,-0.2 -0.650 7.5 167.1 -75.9 119.7 70.5 35.7 59.7 108 365 A E E -F 129 0B 63 21,-2.4 21,-3.1 -2,-0.5 2,-0.4 -0.987 13.9-169.0-131.9 146.2 70.4 32.5 61.8 109 366 A A E +F 128 0B 15 -2,-0.3 2,-0.3 19,-0.2 19,-0.2 -0.998 10.2 167.4-136.1 141.1 69.0 29.1 60.9 110 367 A E E -F 127 0B 74 17,-2.0 17,-2.2 -2,-0.4 2,-0.3 -0.931 16.9-147.0-145.8 168.9 68.4 26.0 63.1 111 368 A T E -F 126 0B 51 -2,-0.3 2,-0.4 15,-0.2 15,-0.2 -0.956 3.2-164.1-139.6 152.1 66.6 22.6 63.0 112 369 A V E -F 125 0B 6 13,-2.7 13,-2.5 -2,-0.3 2,-0.4 -0.944 13.1-149.9-139.5 115.9 64.8 20.3 65.5 113 370 A G E +F 124 0B 7 -2,-0.4 11,-0.3 6,-0.3 8,-0.2 -0.717 21.9 167.5 -86.3 137.1 64.1 16.6 64.7 114 371 A T + 0 0 1 9,-2.0 10,-0.2 6,-0.4 5,-0.2 -0.002 49.1 89.3-136.3 24.3 61.0 15.2 66.3 115 372 A G S > S+ 0 0 3 5,-2.5 3,-2.5 8,-0.7 4,-0.2 0.472 77.4 23.8 -95.3-123.8 60.6 11.9 64.4 116 373 A I G >> S- 0 0 84 1,-0.3 4,-2.5 2,-0.2 3,-1.8 -0.149 138.5 -2.0 -56.3 129.9 62.1 8.5 65.3 117 374 A M G 34 S- 0 0 179 1,-0.3 -1,-0.3 2,-0.2 -2,-0.1 0.709 123.6 -75.5 56.5 27.2 62.9 8.2 69.0 118 375 A G G <4 S+ 0 0 28 -3,-2.5 -1,-0.3 -4,-0.1 -2,-0.2 0.564 131.4 64.1 68.7 11.6 61.7 11.8 69.3 119 376 A R T <4 + 0 0 197 -3,-1.8 -6,-0.3 -5,-0.2 -2,-0.2 0.602 68.6 98.9-138.2 -31.2 64.9 13.0 67.7 120 377 A M S >< S- 0 0 44 -4,-2.5 -5,-2.5 1,-0.1 3,-0.6 -0.175 72.2-117.7 -71.0 166.7 65.5 11.9 64.1 121 378 A G T 3 S+ 0 0 2 -67,-0.4 -32,-0.5 -8,-0.2 -31,-0.2 0.285 86.0 100.7 -96.5 9.1 64.7 14.2 61.1 122 379 A N T 3 S+ 0 0 50 -34,-0.1 2,-0.3 -68,-0.1 -1,-0.2 0.738 103.7 11.7 -60.8 -25.0 61.9 12.2 59.3 123 380 A K S < S+ 0 0 34 -3,-0.6 -9,-2.0 -7,-0.1 -8,-0.7 -0.926 95.4 83.6-141.1 163.4 59.6 14.7 61.0 124 381 A G E -FG 113 143B 0 19,-2.6 19,-3.0 -2,-0.3 2,-0.3 -0.980 64.6 -74.0 143.3-152.8 60.4 18.0 62.9 125 382 A G E -FG 112 142B 0 -13,-2.5 -13,-2.7 -2,-0.3 2,-0.3 -0.989 20.2-160.7-146.4 154.1 61.0 21.6 61.9 126 383 A V E -FG 111 141B 0 15,-2.7 15,-2.9 -2,-0.3 2,-0.3 -0.925 17.2-170.7-126.4 157.9 63.5 24.0 60.4 127 384 A A E -FG 110 140B 0 -17,-2.2 -17,-2.0 -2,-0.3 2,-0.4 -0.997 18.3-159.9-151.9 143.8 63.6 27.8 60.8 128 385 A I E -FG 109 139B 2 11,-2.1 11,-2.8 -2,-0.3 2,-0.3 -0.998 17.5-173.3-119.1 126.5 65.4 30.9 59.5 129 386 A R E +FG 108 138B 10 -21,-3.1 -21,-2.4 -2,-0.4 2,-0.3 -0.877 14.7 150.4-115.4 155.4 65.3 34.0 61.6 130 387 A F E - G 0 137B 0 7,-2.3 7,-2.7 -2,-0.3 2,-0.5 -0.982 41.7-108.3-167.0 170.5 66.5 37.5 60.6 131 388 A Q E -FG 105 136B 42 -26,-3.0 -26,-2.5 -2,-0.3 2,-0.5 -0.974 21.1-167.2-114.8 130.7 66.2 41.2 60.9 132 389 A F E > S-FG 104 135B 0 3,-2.7 3,-2.6 -2,-0.5 172,-0.2 -0.990 72.5 -43.6-118.0 118.9 64.8 43.2 58.0 133 390 A H T 3 S- 0 0 27 -30,-2.5 172,-0.2 -2,-0.5 -28,-0.1 -0.443 125.1 -29.6 48.5-119.6 65.5 46.9 58.7 134 391 A N T 3 S+ 0 0 62 170,-2.6 2,-0.5 -2,-0.2 -1,-0.3 0.192 118.5 99.6-105.3 16.4 64.6 47.1 62.4 135 392 A T E < -G 132 0B 6 -3,-2.6 -3,-2.7 169,-0.2 2,-0.3 -0.887 64.4-140.3-106.4 130.5 61.9 44.3 62.4 136 393 A S E -G 131 0B 19 -2,-0.5 48,-1.8 -5,-0.2 47,-0.4 -0.716 22.7-174.6 -89.1 140.1 62.7 40.8 63.6 137 394 A I E -Gh 130 184B 0 -7,-2.7 -7,-2.3 -2,-0.3 2,-0.4 -0.998 12.7-169.6-139.9 131.0 61.2 37.9 61.6 138 395 A C E -Gh 129 185B 0 46,-2.6 48,-2.1 -2,-0.4 2,-0.5 -0.992 4.4-167.1-125.4 125.7 61.2 34.1 62.2 139 396 A V E -Gh 128 186B 3 -11,-2.8 -11,-2.1 -2,-0.4 2,-0.4 -0.962 8.3-167.6-112.0 123.8 60.0 31.7 59.5 140 397 A V E -Gh 127 187B 0 46,-2.5 48,-2.8 -2,-0.5 2,-0.4 -0.923 9.7-167.2-114.6 137.2 59.3 28.1 60.6 141 398 A N E -Gh 126 188B 0 -15,-2.9 -15,-2.7 -2,-0.4 2,-0.4 -0.994 18.5-178.3-120.8 117.9 58.8 25.1 58.3 142 399 A S E -Gh 125 189B 0 46,-2.0 48,-1.0 -2,-0.4 2,-0.5 -0.946 26.5-163.8-123.6 142.3 57.4 21.9 60.1 143 400 A H E -Gh 124 190B 4 -19,-3.0 -19,-2.6 -2,-0.4 48,-0.2 -0.956 27.5-167.6-116.6 105.0 56.6 18.4 59.1 144 401 A L - 0 0 0 46,-1.7 10,-0.1 -2,-0.5 11,-0.0 -0.493 34.1 -62.7 -94.4 163.8 54.5 17.0 62.0 145 402 A A - 0 0 13 -2,-0.2 -1,-0.2 8,-0.2 9,-0.1 -0.018 54.6-124.7 -51.4 141.1 53.4 13.4 62.7 146 403 A A + 0 0 29 -3,-0.1 4,-0.1 7,-0.0 -1,-0.1 -0.280 59.5 56.1 -80.4 166.1 51.2 11.5 60.2 147 404 A H S > S- 0 0 79 2,-0.1 3,-1.9 1,-0.1 47,-0.1 0.598 77.6 -98.1 89.8 137.3 47.8 9.7 60.5 148 405 A I G > S+ 0 0 60 1,-0.3 3,-0.5 2,-0.1 46,-0.2 0.818 118.8 51.0 -47.1 -41.7 44.3 10.8 61.8 149 406 A E G 3 S+ 0 0 130 1,-0.2 3,-0.4 2,-0.1 -1,-0.3 0.508 92.5 74.2 -86.2 -1.3 44.8 9.2 65.2 150 407 A E G <> + 0 0 89 -3,-1.9 4,-1.9 1,-0.2 3,-0.4 -0.012 52.5 123.9-102.1 32.0 48.2 10.8 66.1 151 408 A Y H <> S+ 0 0 75 -3,-0.5 4,-2.3 1,-0.3 -1,-0.2 0.834 72.0 56.0 -63.2 -34.3 46.9 14.4 66.8 152 409 A E H > S+ 0 0 141 -3,-0.4 4,-2.4 2,-0.2 -1,-0.3 0.875 106.3 50.9 -65.4 -37.0 48.5 14.4 70.3 153 410 A R H > S+ 0 0 93 -3,-0.4 4,-2.8 2,-0.2 -2,-0.2 0.888 108.2 52.2 -67.9 -38.6 51.9 13.6 68.8 154 411 A R H X S+ 0 0 0 -4,-1.9 4,-2.6 2,-0.2 -2,-0.2 0.943 109.2 49.9 -58.5 -47.5 51.4 16.5 66.4 155 412 A N H X S+ 0 0 9 -4,-2.3 4,-2.4 1,-0.2 -2,-0.2 0.939 113.1 46.8 -55.3 -48.0 50.7 18.8 69.3 156 413 A Q H X S+ 0 0 86 -4,-2.4 4,-2.8 2,-0.2 -1,-0.2 0.847 108.1 55.1 -64.3 -37.0 53.8 17.5 71.0 157 414 A D H X S+ 0 0 0 -4,-2.8 4,-2.4 2,-0.2 -1,-0.2 0.937 109.6 48.5 -61.0 -44.8 55.9 17.9 67.9 158 415 A Y H X S+ 0 0 24 -4,-2.6 4,-2.3 1,-0.2 -2,-0.2 0.949 112.4 46.9 -58.1 -52.6 54.8 21.5 67.8 159 416 A K H X S+ 0 0 88 -4,-2.4 4,-2.4 1,-0.2 -1,-0.2 0.890 112.0 52.1 -57.6 -40.9 55.6 22.0 71.5 160 417 A D H X S+ 0 0 40 -4,-2.8 4,-2.2 2,-0.2 5,-0.2 0.874 108.7 48.7 -66.6 -37.9 59.0 20.3 71.0 161 418 A I H X S+ 0 0 0 -4,-2.4 4,-1.9 2,-0.2 -1,-0.2 0.924 113.0 49.8 -65.4 -41.6 60.0 22.5 68.1 162 419 A C H < S+ 0 0 38 -4,-2.3 17,-0.4 -5,-0.2 -2,-0.2 0.905 116.4 39.4 -65.1 -43.5 59.0 25.6 70.2 163 420 A S H < S+ 0 0 79 -4,-2.4 -1,-0.2 -5,-0.2 -2,-0.2 0.852 121.9 40.1 -76.1 -34.7 61.0 24.6 73.3 164 421 A R H < S+ 0 0 101 -4,-2.2 2,-0.6 -5,-0.2 -2,-0.2 0.703 87.0 98.2 -92.0 -20.8 64.1 23.2 71.6 165 422 A M < + 0 0 1 -4,-1.9 14,-0.4 -5,-0.2 2,-0.4 -0.593 49.7 167.9 -73.1 113.8 64.6 25.7 68.7 166 423 A Q - 0 0 107 -2,-0.6 2,-0.3 -55,-0.1 12,-0.2 -0.997 18.5-155.5-129.9 130.7 67.3 28.2 69.9 167 424 A F B -K 177 0C 2 10,-2.8 10,-1.4 -2,-0.4 -57,-0.1 -0.779 23.1-109.0-103.8 147.7 69.1 30.8 67.8 168 425 A C - 0 0 75 -2,-0.3 -1,-0.1 8,-0.2 3,-0.0 -0.268 35.4-161.7 -63.0 161.2 72.5 32.5 68.3 169 426 A Q - 0 0 60 5,-0.1 -1,-0.0 1,-0.1 -63,-0.0 -0.924 30.5-118.3-142.9 157.6 72.5 36.1 69.3 170 427 A P S S+ 0 0 102 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.793 101.9 62.5 -69.9 -25.9 75.1 38.9 69.3 171 428 A D - 0 0 69 1,-0.1 3,-0.5 4,-0.1 0, 0.0 -0.880 59.6-171.1-106.0 110.2 74.9 39.3 73.1 172 429 A P S S+ 0 0 125 0, 0.0 -1,-0.1 0, 0.0 -4,-0.0 0.591 82.0 72.6 -75.6 -9.9 75.9 36.3 75.3 173 430 A S S S+ 0 0 110 2,-0.1 -2,-0.0 0, 0.0 0, 0.0 0.944 90.9 69.7 -56.1 -51.6 74.5 38.0 78.4 174 431 A L S S- 0 0 90 -3,-0.5 3,-0.1 1,-0.1 -5,-0.1 -0.185 96.5 -97.6 -73.5 157.2 71.0 37.4 77.2 175 432 A P - 0 0 101 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.485 57.2 -88.7 -67.3 145.8 69.1 34.1 77.0 176 433 A P - 0 0 70 0, 0.0 2,-0.2 0, 0.0 -8,-0.2 -0.113 49.4 -92.4 -56.9 154.6 69.2 32.6 73.4 177 434 A L B -K 167 0C 13 -10,-1.4 -10,-2.8 -3,-0.1 2,-0.2 -0.488 40.3-165.5 -66.2 131.4 66.4 33.6 70.9 178 435 A T > - 0 0 45 -12,-0.2 3,-0.8 -2,-0.2 -12,-0.1 -0.648 37.9 -99.4-104.4 172.3 63.4 31.4 70.7 179 436 A I T 3 S+ 0 0 5 -14,-0.4 3,-0.1 -17,-0.4 -41,-0.1 0.922 120.5 57.2 -55.9 -46.6 60.8 31.4 67.9 180 437 A S T 3 S+ 0 0 86 1,-0.2 2,-1.6 -18,-0.2 -1,-0.2 0.692 85.9 80.1 -64.1 -21.8 58.4 33.5 70.0 181 438 A N S < S+ 0 0 101 -3,-0.8 2,-0.3 3,-0.0 -1,-0.2 -0.362 76.3 97.8 -85.3 58.5 60.9 36.4 70.5 182 439 A H S S- 0 0 16 -2,-1.6 -45,-0.1 1,-0.1 3,-0.1 -0.995 73.6-133.0-142.3 148.0 60.2 37.9 67.1 183 440 A D S S+ 0 0 86 -47,-0.4 91,-0.6 -2,-0.3 2,-0.4 0.870 99.4 29.3 -63.6 -38.5 58.0 40.8 65.8 184 441 A V E -hI 137 273B 2 -48,-1.8 -46,-2.6 89,-0.2 2,-0.4 -0.992 66.7-176.2-130.1 129.2 56.8 38.6 63.0 185 442 A I E -hI 138 272B 5 87,-2.6 87,-2.3 -2,-0.4 2,-0.5 -0.998 1.9-174.8-125.4 125.3 56.4 34.8 62.9 186 443 A L E -hI 139 271B 0 -48,-2.1 -46,-2.5 -2,-0.4 2,-0.5 -0.992 8.0-171.1-115.8 123.3 55.3 32.9 59.8 187 444 A W E +hI 140 270B 0 83,-2.6 83,-3.3 -2,-0.5 2,-0.3 -0.982 13.6 161.2-120.7 124.3 54.8 29.2 60.4 188 445 A L E +hI 141 269B 0 -48,-2.8 -46,-2.0 -2,-0.5 2,-0.3 -0.868 12.2 99.1-134.2 164.7 54.2 26.9 57.4 189 446 A G E S-hI 142 268B 0 79,-1.6 79,-2.1 -2,-0.3 2,-1.2 -0.875 76.2 -54.8 154.1-179.9 54.4 23.2 56.7 190 447 A D E +hI 143 267B 1 -48,-1.0 -46,-1.7 -2,-0.3 77,-0.2 -0.808 52.4 175.0 -86.1 88.8 52.7 19.8 56.3 191 448 A L - 0 0 0 75,-1.7 -1,-0.2 -2,-1.2 76,-0.2 0.655 28.2-145.2 -77.3 -15.9 51.1 20.0 59.7 192 449 A N + 0 0 5 74,-1.3 2,-0.2 1,-0.2 74,-0.2 0.556 39.7 153.8 70.2 13.3 49.3 16.7 58.9 193 450 A Y - 0 0 0 73,-0.4 -1,-0.2 72,-0.3 2,-0.2 -0.515 24.8-163.0 -75.5 144.3 46.1 17.5 60.8 194 451 A R - 0 0 13 -46,-0.2 26,-2.7 -2,-0.2 2,-0.6 -0.477 26.6 -79.0-119.8-176.4 43.1 15.6 59.4 195 452 A I B -L 219 0D 9 68,-0.4 24,-0.2 24,-0.2 8,-0.1 -0.830 46.4-144.0 -93.4 113.8 39.3 15.6 59.4 196 453 A E - 0 0 65 22,-3.0 2,-3.0 -2,-0.6 -47,-0.0 -0.259 65.8 -3.0 -68.7 160.4 37.8 14.0 62.6 197 454 A E S S+ 0 0 159 -2,-0.0 -1,-0.1 0, 0.0 -2,-0.0 -0.201 96.9 103.4 65.0 -57.9 34.6 11.9 62.8 198 455 A L S S- 0 0 35 -2,-3.0 2,-0.2 17,-0.1 -3,-0.1 -0.179 70.2-119.7 -62.7 152.4 33.3 12.0 59.1 199 456 A D > - 0 0 93 1,-0.1 4,-2.4 63,-0.0 3,-0.5 -0.547 29.0-102.3 -92.5 162.7 33.9 9.0 56.9 200 457 A V H > S+ 0 0 41 1,-0.3 4,-2.3 2,-0.2 5,-0.2 0.846 120.6 50.8 -55.3 -40.9 35.8 9.1 53.7 201 458 A E H > S+ 0 0 140 2,-0.2 4,-1.6 1,-0.2 -1,-0.3 0.877 110.6 48.3 -66.5 -41.0 32.7 9.2 51.5 202 459 A K H > S+ 0 0 88 -3,-0.5 4,-2.6 2,-0.2 -2,-0.2 0.909 110.8 51.9 -66.1 -42.7 31.2 12.1 53.4 203 460 A V H X S+ 0 0 1 -4,-2.4 4,-1.6 1,-0.2 -2,-0.2 0.935 111.5 46.4 -56.9 -49.3 34.4 14.1 53.3 204 461 A K H X S+ 0 0 57 -4,-2.3 4,-1.5 -5,-0.2 -1,-0.2 0.805 111.5 52.3 -66.2 -30.3 34.7 13.6 49.5 205 462 A K H X S+ 0 0 101 -4,-1.6 4,-2.4 2,-0.2 3,-0.4 0.963 106.6 51.4 -70.5 -53.1 31.0 14.6 49.0 206 463 A L H <>S+ 0 0 2 -4,-2.6 5,-2.5 1,-0.2 4,-0.5 0.860 110.7 51.1 -47.6 -39.7 31.4 17.8 51.0 207 464 A I H <5S+ 0 0 6 -4,-1.6 3,-0.3 2,-0.2 -1,-0.2 0.855 108.1 49.6 -70.0 -36.7 34.4 18.7 48.8 208 465 A E H <5S+ 0 0 155 -4,-1.5 -2,-0.2 -3,-0.4 -1,-0.2 0.855 113.2 48.1 -69.3 -34.0 32.4 18.0 45.6 209 466 A E T <5S- 0 0 95 -4,-2.4 -1,-0.2 -5,-0.1 -2,-0.2 0.584 109.7-130.1 -75.8 -13.6 29.7 20.3 47.0 210 467 A K T 5 + 0 0 149 -4,-0.5 2,-1.5 -3,-0.3 3,-0.2 0.773 54.7 151.1 62.6 30.6 32.4 22.9 47.9 211 468 A D >< + 0 0 62 -5,-2.5 4,-2.0 1,-0.2 -1,-0.2 -0.550 5.1 155.1 -90.0 72.0 31.1 23.1 51.5 212 469 A F H > + 0 0 31 -2,-1.5 4,-2.6 1,-0.2 -1,-0.2 0.796 65.2 61.1 -73.3 -29.6 34.5 24.0 53.0 213 470 A Q H > S+ 0 0 156 -3,-0.2 4,-0.9 2,-0.2 -1,-0.2 0.904 109.7 42.9 -61.0 -41.6 33.0 25.8 56.1 214 471 A M H 4 S+ 0 0 68 2,-0.2 3,-0.5 1,-0.2 4,-0.4 0.910 114.5 48.0 -73.1 -46.9 31.3 22.5 57.1 215 472 A L H >< S+ 0 0 0 -4,-2.0 3,-1.7 1,-0.2 -2,-0.2 0.917 108.6 57.8 -57.4 -41.4 34.3 20.3 56.4 216 473 A Y H >< S+ 0 0 70 -4,-2.6 3,-1.7 1,-0.3 -1,-0.2 0.779 90.8 69.3 -62.7 -27.6 36.4 22.8 58.3 217 474 A A T 3< S+ 0 0 48 -4,-0.9 -1,-0.3 -3,-0.5 -2,-0.2 0.734 104.1 44.9 -63.0 -19.1 34.2 22.4 61.5 218 475 A Y T < S+ 0 0 58 -3,-1.7 -22,-3.0 -4,-0.4 -1,-0.3 0.280 84.0 124.2-105.2 6.2 35.7 18.9 61.7 219 476 A D B <> -L 195 0D 0 -3,-1.7 4,-2.0 -24,-0.2 -24,-0.2 -0.525 57.2-143.0 -75.3 132.6 39.4 19.9 61.0 220 477 A Q H > S+ 0 0 1 -26,-2.7 4,-3.0 -2,-0.3 5,-0.2 0.840 98.0 54.2 -67.1 -35.6 41.8 18.8 63.8 221 478 A L H > S+ 0 0 1 -27,-0.2 4,-3.0 2,-0.2 5,-0.2 0.956 108.4 49.7 -65.3 -48.0 43.9 21.9 63.7 222 479 A K H > S+ 0 0 82 2,-0.2 4,-2.4 1,-0.2 -2,-0.2 0.928 114.1 46.0 -49.6 -51.0 40.9 24.2 64.1 223 480 A I H X S+ 0 0 70 -4,-2.0 4,-2.1 2,-0.2 -2,-0.2 0.933 113.9 47.2 -62.7 -48.0 39.8 22.0 67.1 224 481 A Q H <>S+ 0 0 24 -4,-3.0 5,-2.0 1,-0.2 6,-0.7 0.876 111.4 51.4 -62.8 -38.8 43.3 21.9 68.7 225 482 A V H ><5S+ 0 0 48 -4,-3.0 3,-1.1 -5,-0.2 -1,-0.2 0.920 109.7 50.3 -63.1 -43.1 43.7 25.7 68.2 226 483 A A H 3<5S+ 0 0 75 -4,-2.4 -2,-0.2 1,-0.3 -1,-0.2 0.890 110.1 50.2 -61.1 -39.1 40.3 26.3 70.0 227 484 A A T 3<5S- 0 0 65 -4,-2.1 -1,-0.3 -5,-0.2 -2,-0.2 0.489 111.4-125.9 -78.2 -3.8 41.4 24.0 72.8 228 485 A K T < 5S+ 0 0 146 -3,-1.1 -3,-0.2 -4,-0.3 4,-0.1 0.744 74.1 124.2 64.5 29.2 44.7 26.0 73.1 229 486 A T S - 0 0 1 -2,-0.3 3,-1.8 1,-0.2 2,-0.2 0.835 69.7-165.7 50.6 44.6 49.5 27.6 67.8 232 489 A E T 3 S+ 0 0 123 1,-0.3 -1,-0.2 -4,-0.1 3,-0.1 -0.425 72.3 5.8 -63.7 121.3 48.6 29.9 70.7 233 490 A G T 3 S+ 0 0 56 1,-0.3 -1,-0.3 -2,-0.2 40,-0.2 0.410 101.4 124.7 84.0 -1.8 48.1 33.5 69.4 234 491 A F < - 0 0 24 -3,-1.8 2,-0.4 38,-0.1 -1,-0.3 -0.595 48.4-146.4 -86.0 153.3 48.5 32.5 65.7 235 492 A T B -J 271 0B 69 36,-2.6 36,-2.1 -2,-0.2 2,-0.4 -0.921 7.6-163.9-114.7 143.6 46.0 33.2 63.0 236 493 A E - 0 0 32 -2,-0.4 34,-0.1 34,-0.2 3,-0.1 -0.992 23.0-122.5-118.5 139.8 45.1 31.1 60.0 237 494 A G - 0 0 12 32,-0.5 32,-0.1 -2,-0.4 2,-0.0 -0.275 44.9 -75.5 -70.4 163.3 43.2 32.5 57.0 238 495 A E - 0 0 155 1,-0.1 2,-0.8 2,-0.1 -1,-0.1 -0.338 44.2-124.2 -62.3 134.8 39.9 31.0 55.8 239 496 A L + 0 0 8 1,-0.2 -23,-0.1 -3,-0.1 -1,-0.1 -0.757 44.7 156.5 -82.5 110.2 40.4 27.8 53.9 240 497 A T + 0 0 86 -2,-0.8 2,-0.3 41,-0.3 -1,-0.2 0.305 52.3 77.7-116.8 3.2 38.7 28.4 50.5 241 498 A F S S- 0 0 16 -29,-0.1 3,-0.1 1,-0.1 43,-0.0 -0.702 88.2-100.1-106.8 162.5 40.6 25.8 48.5 242 499 A Q - 0 0 49 -2,-0.3 -2,-0.1 1,-0.2 -1,-0.1 -0.498 57.2 -67.8 -81.1 155.9 40.0 22.0 48.6 243 500 A P - 0 0 0 0, 0.0 22,-0.3 0, 0.0 -1,-0.2 0.019 39.0-144.4 -39.5 141.6 42.1 19.6 50.7 244 501 A T + 0 0 0 20,-0.8 49,-1.9 -3,-0.1 2,-0.3 0.426 62.4 95.6-100.2 -1.4 45.7 19.3 49.4 245 502 A Y B +M 264 0E 14 19,-1.3 19,-2.2 47,-0.2 47,-0.1 -0.971 63.5 20.4-140.1 148.7 46.2 15.7 50.2 246 503 A K + 0 0 29 45,-0.5 9,-2.8 -2,-0.3 2,-0.3 0.474 62.5 151.1-123.6 130.1 46.0 12.9 49.1 247 504 A Y B -N 254 0F 2 44,-2.4 2,-0.3 7,-0.3 7,-0.2 -0.768 49.3-104.5-111.5 150.6 46.2 12.6 45.3 248 505 A D > - 0 0 41 5,-2.1 3,-1.6 -2,-0.3 5,-0.3 -0.587 54.3 -99.9 -62.3 131.6 47.4 10.0 42.8 249 506 A T T 3 S+ 0 0 81 -2,-0.3 40,-0.2 1,-0.2 42,-0.1 -0.242 108.3 22.9 -49.0 141.0 50.7 11.3 41.4 250 507 A G T 3 S+ 0 0 54 38,-2.8 2,-0.2 40,-0.2 -1,-0.2 0.512 119.7 64.4 76.6 7.5 50.3 12.9 38.0 251 508 A S S < S- 0 0 21 -3,-1.6 -1,-0.2 37,-0.3 -4,-0.1 -0.853 78.9-120.4-148.2 177.4 46.6 13.6 38.5 252 509 A D S S+ 0 0 68 -2,-0.2 2,-0.3 -3,-0.1 -3,-0.1 0.057 74.8 115.8-110.0 18.4 43.9 15.5 40.4 253 510 A D S S- 0 0 100 -5,-0.3 -5,-2.1 1,-0.1 -2,-0.1 -0.643 72.7-106.1 -90.1 148.5 42.2 12.2 41.6 254 511 A W B -N 247 0F 44 -2,-0.3 -7,-0.3 -7,-0.2 -1,-0.1 -0.436 60.1 -68.4 -68.1 145.4 41.9 11.2 45.2 255 512 A D - 0 0 6 -9,-2.8 -1,-0.2 1,-0.2 -8,-0.1 -0.044 49.4-178.0 -34.0 113.0 44.3 8.3 46.3 256 513 A T + 0 0 106 -3,-0.1 -1,-0.2 4,-0.1 -2,-0.1 0.191 46.2 110.6-104.5 13.4 43.1 5.1 44.5 257 514 A S S > S- 0 0 52 1,-0.1 3,-0.6 4,-0.0 -9,-0.0 -0.091 90.4 -89.0 -71.8-177.1 45.7 2.9 46.2 258 515 A E T 3 S+ 0 0 109 1,-0.2 -1,-0.1 2,-0.1 -3,-0.0 0.889 126.6 58.1 -65.2 -40.4 44.8 0.2 48.8 259 516 A K T 3 S- 0 0 125 1,-0.0 -1,-0.2 2,-0.0 -4,-0.0 0.760 85.2-164.9 -63.8 -22.9 45.1 2.6 51.7 260 517 A C < - 0 0 60 -3,-0.6 -4,-0.1 1,-0.1 -2,-0.1 0.871 18.0-145.3 40.3 63.6 42.5 4.9 50.0 261 518 A R - 0 0 75 1,-0.1 -1,-0.1 -14,-0.0 -6,-0.1 -0.213 6.6-117.9 -69.1 143.8 43.2 7.9 52.2 262 519 A A - 0 0 21 1,-0.1 -1,-0.1 -8,-0.1 -67,-0.1 -0.611 40.9-103.2 -71.0 133.3 40.7 10.4 53.4 263 520 A P + 0 0 1 0, 0.0 -68,-0.4 0, 0.0 2,-0.3 -0.160 46.5 179.8 -54.1 154.5 41.3 14.0 52.1 264 521 A A B -M 245 0E 0 -19,-2.2 2,-1.6 -70,-0.1 -19,-1.3 -0.984 41.8-120.9-158.3 145.4 42.9 16.4 54.5 265 522 A W + 0 0 0 -2,-0.3 -72,-0.3 -22,-0.3 -74,-0.1 -0.699 52.5 153.8 -83.9 78.7 44.1 20.1 54.7 266 523 A C + 0 0 0 -2,-1.6 -75,-1.7 -74,-0.2 -74,-1.3 0.824 50.6 70.3 -73.8 -32.6 47.5 18.8 55.6 267 524 A D E +I 190 0B 0 -3,-0.3 2,-0.3 -77,-0.2 -77,-0.2 -0.806 66.2 162.0-108.3 115.1 49.3 21.9 54.3 268 525 A R E -I 189 0B 0 -79,-2.1 -79,-1.6 -2,-0.6 2,-0.4 -0.843 29.2-155.2-136.6 157.1 48.9 25.1 56.2 269 526 A I E +I 188 0B 0 -2,-0.3 -32,-0.5 -81,-0.2 2,-0.3 -0.987 20.5 172.7-136.9 128.5 50.3 28.6 56.8 270 527 A L E -I 187 0B 4 -83,-3.3 -83,-2.6 -2,-0.4 2,-0.3 -0.881 9.2-160.0-131.1 166.4 49.7 30.6 60.0 271 528 A W E -IJ 186 235B 31 -36,-2.1 -36,-2.6 -2,-0.3 2,-0.3 -0.982 12.2-167.8-149.9 156.9 51.1 33.9 61.4 272 529 A K E +I 185 0B 86 -87,-2.3 -87,-2.6 -2,-0.3 2,-0.2 -0.979 42.5 71.7-146.4 132.2 51.6 36.0 64.5 273 530 A G E S-I 184 0B 37 -2,-0.3 3,-0.5 -40,-0.2 -89,-0.2 -0.692 70.6 -68.5 147.1 165.9 52.6 39.7 64.8 274 531 A K S S+ 0 0 175 -91,-0.6 28,-0.2 1,-0.2 -2,-0.1 -0.397 104.7 23.8 -77.1 157.4 51.6 43.3 64.4 275 532 A N S S+ 0 0 94 1,-0.2 27,-2.5 26,-0.1 2,-0.4 0.815 84.5 140.7 57.1 38.9 50.9 45.0 61.0 276 533 A I E +E 301 0A 22 -3,-0.5 2,-0.4 25,-0.2 25,-0.2 -0.944 24.4 176.6-113.0 133.8 50.2 41.8 59.1 277 534 A T E -E 300 0A 84 23,-2.0 23,-2.7 -2,-0.4 2,-0.5 -0.990 23.3-138.8-132.7 125.6 47.4 41.4 56.4 278 535 A Q E +E 299 0A 43 -2,-0.4 21,-0.2 21,-0.2 3,-0.1 -0.733 18.9 179.4 -82.9 122.7 46.8 38.3 54.4 279 536 A L E + 0 0 74 19,-3.1 2,-0.3 -2,-0.5 20,-0.2 0.605 67.1 1.6 -93.9 -19.3 46.1 39.1 50.8 280 537 A S E -E 298 0A 30 18,-1.1 18,-0.8 2,-0.0 -1,-0.3 -0.974 45.3-170.8-167.8 151.1 45.6 35.5 49.6 281 538 A Y E +E 297 0A 11 -2,-0.3 -41,-0.3 16,-0.2 2,-0.3 -0.868 34.3 150.3-151.6 112.4 45.7 31.9 50.7 282 539 A Q E -E 296 0A 90 14,-2.3 14,-2.8 -2,-0.3 2,-0.3 -0.942 38.6-137.0-145.7 154.4 45.5 29.3 47.9 283 540 A S E -E 295 0A 21 -2,-0.3 2,-0.5 12,-0.2 12,-0.2 -0.732 23.7-132.6-106.9 168.0 46.5 25.8 46.7 284 541 A H > + 0 0 17 10,-1.7 3,-1.2 -2,-0.3 -255,-0.0 -0.850 22.5 178.8-128.7 90.6 47.9 25.1 43.3 285 542 A M T 3 S+ 0 0 54 -2,-0.5 -1,-0.1 1,-0.2 0, 0.0 0.766 71.2 74.6 -64.7 -29.3 46.1 22.2 41.6 286 543 A A T 3 S+ 0 0 54 -258,-0.1 2,-0.6 2,-0.1 -1,-0.2 0.648 77.9 84.9 -64.8 -16.8 48.0 22.4 38.3 287 544 A L < + 0 0 0 -3,-1.2 3,-0.1 1,-0.1 -3,-0.1 -0.795 49.1 166.6 -91.8 123.0 51.2 20.9 39.9 288 545 A K + 0 0 77 -2,-0.6 -38,-2.8 1,-0.1 -37,-0.3 0.240 41.5 104.9-124.8 11.4 51.0 17.2 39.9 289 546 A T S S+ 0 0 7 -40,-0.2 2,-0.2 -39,-0.1 -1,-0.1 0.819 85.5 42.8 -58.8 -29.5 54.5 15.9 40.7 290 547 A S S S- 0 0 0 2,-0.4 -40,-0.2 -3,-0.1 -39,-0.2 -0.618 81.6-118.3-118.9 168.0 53.4 15.0 44.2 291 548 A D S S+ 0 0 10 -2,-0.2 -44,-2.4 -42,-0.1 -45,-0.5 0.500 104.0 61.8 -80.3 -8.0 50.6 13.4 46.1 292 549 A H S S- 0 0 4 -276,-0.6 -2,-0.4 -46,-0.2 -47,-0.2 -0.857 81.8-133.3-106.0 154.3 50.2 16.8 47.8 293 550 A K - 0 0 0 -49,-1.9 -277,-0.2 -2,-0.3 -8,-0.1 -0.830 31.1-108.6 -96.1 146.3 49.4 20.1 46.1 294 551 A P - 0 0 0 0, 0.0 -10,-1.7 0, 0.0 2,-0.3 -0.385 29.5-148.9 -69.5 153.9 51.5 23.2 47.1 295 552 A V E -AE 14 283A 0 -281,-2.7 -281,-2.2 -12,-0.2 2,-0.3 -0.921 14.3-175.7-124.5 147.0 50.0 26.0 49.2 296 553 A S E -AE 13 282A 2 -14,-2.8 -14,-2.3 -2,-0.3 2,-0.3 -0.964 10.6-173.5-140.0 156.8 50.8 29.7 49.1 297 554 A S E -AE 12 281A 0 -285,-2.1 -285,-2.7 -2,-0.3 2,-0.4 -0.964 11.0-153.8-146.9 136.4 50.0 32.9 50.9 298 555 A V E -AE 11 280A 8 -18,-0.8 -19,-3.1 -2,-0.3 -18,-1.1 -0.950 18.8-172.2-109.5 134.8 50.9 36.5 50.2 299 556 A F E -AE 10 278A 0 -289,-2.8 -289,-2.2 -2,-0.4 2,-0.6 -0.918 24.8-139.8-122.7 149.1 51.0 39.0 53.1 300 557 A D E -AE 9 277A 36 -23,-2.7 -23,-2.0 -2,-0.3 2,-0.5 -0.961 32.1-171.9-100.7 122.2 51.5 42.7 53.4 301 558 A I E -AE 8 276A 0 -293,-2.8 -293,-2.5 -2,-0.6 2,-0.4 -0.981 21.1-133.8-126.2 124.9 53.7 43.2 56.4 302 559 A G E -A 7 0A 4 -27,-2.5 2,-0.4 -2,-0.5 -295,-0.2 -0.629 27.0-167.2 -74.8 123.6 54.6 46.5 58.1 303 560 A V E -A 6 0A 0 -297,-2.9 -297,-2.6 -2,-0.4 2,-0.8 -0.917 25.0-116.2-117.9 139.5 58.3 46.8 58.7 304 561 A R E -A 5 0A 106 -2,-0.4 -170,-2.6 -172,-0.2 2,-0.4 -0.663 39.3-174.9 -76.3 109.4 60.1 49.3 60.9 305 562 A V E -A 4 0A 9 -301,-3.2 -301,-2.5 -2,-0.8 2,-0.5 -0.839 26.5-117.0-109.0 143.9 62.4 51.4 58.6 306 563 A V E -A 3 0A 52 -2,-0.4 -303,-0.3 -303,-0.2 2,-0.1 -0.672 29.6-126.0 -78.7 123.8 64.8 54.0 59.6 307 564 A A - 0 0 42 -305,-2.9 -305,-0.4 -2,-0.5 2,-0.3 -0.470 28.2-112.3 -64.0 137.6 64.0 57.5 58.3 308 565 A H - 0 0 142 -2,-0.1 2,-0.5 -307,-0.1 -1,-0.1 -0.621 27.5-138.7 -74.1 130.9 66.9 59.1 56.3 309 566 A H 0 0 182 -2,-0.3 -1,-0.0 1,-0.2 -3,-0.0 -0.807 360.0 360.0 -91.6 125.8 68.3 62.2 58.1 310 567 A H 0 0 204 -2,-0.5 -1,-0.2 0, 0.0 -2,-0.0 0.554 360.0 360.0-124.8 360.0 69.2 65.2 55.9