==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-MAR-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CYTOKINE/SIGNALING PROTEIN 23-AUG-10 3OJV . COMPND 2 MOLECULE: HEPARIN-BINDING GROWTH FACTOR 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.BEENKEN,M.MOHAMMADI . 692 4 4 4 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 33833.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 427 61.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 20 2.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 222 32.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 12 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 8 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 91 13.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 64 9.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 6 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 20 6 4 10 2 6 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 4 2 0 4 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 21 A G 0 0 69 0, 0.0 2,-0.8 0, 0.0 402,-0.4 0.000 360.0 360.0 360.0 -73.9 -8.0 -3.7 -2.3 2 22 A N > - 0 0 68 4,-0.1 3,-4.1 1,-0.1 400,-0.1 -0.814 360.0-140.6 -94.8 105.7 -8.5 -4.3 -6.1 3 23 A Y T 3 S+ 0 0 5 -2,-0.8 38,-0.4 400,-0.4 -1,-0.1 0.627 102.8 56.3 -38.5 -20.4 -5.1 -4.1 -7.8 4 24 A K T 3 S+ 0 0 46 36,-0.1 -1,-0.3 438,-0.1 438,-0.1 0.709 94.9 82.3 -87.2 -22.9 -6.7 -2.2 -10.7 5 25 A K S < S- 0 0 40 -3,-4.1 36,-0.3 1,-0.1 34,-0.0 -0.449 91.8 -92.7 -82.8 154.3 -8.1 0.5 -8.4 6 26 A P - 0 0 44 0, 0.0 126,-0.5 0, 0.0 2,-0.3 -0.216 44.4-176.2 -64.8 157.0 -6.0 3.5 -7.2 7 27 A K B -A 39 0A 24 32,-3.0 32,-3.2 124,-0.2 2,-0.5 -0.944 24.0-123.6-146.6 166.4 -4.1 3.4 -3.9 8 28 A L E -B 130 0A 0 122,-3.4 122,-3.5 -2,-0.3 2,-1.0 -0.951 20.8-135.8-115.8 132.4 -2.0 5.7 -1.7 9 29 A L E -B 129 0A 2 28,-0.5 9,-2.4 -2,-0.5 2,-0.5 -0.784 22.5-159.4 -93.0 103.4 1.5 4.6 -0.8 10 30 A Y E -BC 128 17A 3 118,-2.9 118,-3.3 -2,-1.0 2,-0.3 -0.709 6.9-142.9 -85.0 122.0 1.9 5.4 2.9 11 31 A C E -B 127 0A 0 5,-4.3 4,-0.3 -2,-0.5 116,-0.2 -0.621 6.7-142.6 -83.8 142.2 5.5 5.7 4.2 12 32 A S S S+ 0 0 8 114,-2.8 112,-0.1 111,-0.3 -1,-0.1 0.702 88.7 69.0 -77.3 -18.0 6.1 4.3 7.7 13 33 A N S S- 0 0 15 113,-0.3 95,-0.1 110,-0.3 94,-0.1 0.814 122.3 -2.2 -65.7-111.9 8.5 7.2 8.4 14 34 A G S S- 0 0 8 93,-0.5 -1,-0.2 92,-0.2 -2,-0.1 0.548 102.7-109.6 -61.5 0.9 6.7 10.5 8.7 15 35 A G + 0 0 2 -4,-0.3 2,-0.3 1,-0.2 272,-0.2 0.950 65.8 164.4 68.4 45.8 3.6 8.7 7.9 16 36 A H - 0 0 4 -5,-0.2 -5,-4.3 90,-0.1 2,-0.4 -0.670 40.7-130.0 -98.9 154.7 3.5 10.4 4.5 17 37 A F E -CD 10 29A 2 12,-3.1 12,-0.7 -7,-0.3 -7,-0.2 -0.856 36.6-110.9 -97.5 134.5 1.6 9.5 1.3 18 38 A L E - D 0 28A 3 -9,-2.4 2,-0.4 -2,-0.4 -9,-0.3 -0.488 41.3-164.9 -68.4 133.7 3.8 9.4 -1.7 19 39 A R E - D 0 27A 45 8,-2.3 8,-1.5 -2,-0.2 2,-0.6 -0.984 18.8-158.7-131.5 131.9 3.0 12.3 -3.9 20 40 A I E - D 0 26A 1 16,-2.4 6,-0.3 -2,-0.4 38,-0.1 -0.925 19.6-152.4-105.5 119.1 3.9 13.1 -7.6 21 41 A L > - 0 0 32 4,-4.3 3,-3.2 -2,-0.6 4,-0.4 -0.745 23.7-117.8 -96.4 141.2 3.7 16.8 -8.4 22 42 A P T 3 S+ 0 0 80 0, 0.0 -1,-0.1 0, 0.0 4,-0.1 0.785 114.3 64.7 -42.0 -37.8 2.9 18.2 -11.9 23 43 A D T 3 S- 0 0 77 1,-0.1 3,-0.1 2,-0.1 47,-0.0 0.417 125.4-104.8 -70.2 4.6 6.3 19.8 -11.9 24 44 A G S < S+ 0 0 12 -3,-3.2 46,-2.2 1,-0.3 2,-0.3 0.536 80.6 133.3 84.2 6.1 7.6 16.3 -11.9 25 45 A T B -E 69 0A 71 -4,-0.4 -4,-4.3 44,-0.2 2,-0.5 -0.713 40.1-158.8 -92.4 143.1 8.7 16.5 -8.2 26 46 A V E +D 20 0A 4 42,-0.9 86,-0.6 -2,-0.3 -6,-0.2 -0.976 28.3 137.8-125.3 120.0 7.8 13.7 -5.8 27 47 A D E -DF 19 111A 36 -8,-1.5 -8,-2.3 -2,-0.5 2,-0.3 -0.350 45.3 -87.7-132.0-147.5 7.7 14.3 -2.1 28 48 A G E +D 18 0A 7 82,-1.7 2,-0.3 -10,-0.2 -10,-0.2 -0.843 34.5 173.4-131.3 169.1 5.4 13.3 0.8 29 49 A T E -D 17 0A 18 -12,-0.7 -12,-3.1 -2,-0.3 81,-0.0 -0.966 35.4-147.0-171.4 157.2 2.3 14.6 2.5 30 50 A R + 0 0 95 -2,-0.3 2,-2.1 -14,-0.2 -1,-0.1 0.367 69.2 114.3-107.2 -4.2 -0.4 13.9 5.1 31 51 A D > - 0 0 77 1,-0.2 3,-2.4 -14,-0.1 6,-0.1 -0.488 44.4-177.8 -70.9 82.2 -2.9 15.7 3.1 32 52 A R T 3 S+ 0 0 76 -2,-2.1 -1,-0.2 1,-0.3 -2,-0.0 0.204 78.0 61.5 -71.5 20.6 -5.1 12.7 2.3 33 53 A S T 3 S+ 0 0 99 100,-0.1 -1,-0.3 3,-0.0 -2,-0.1 0.413 77.1 118.5-120.3 -6.4 -7.3 14.9 0.2 34 54 A D < - 0 0 29 -3,-2.4 3,-0.3 1,-0.1 4,-0.1 -0.096 61.5-141.4 -56.0 158.8 -4.6 15.8 -2.2 35 55 A Q S S+ 0 0 34 1,-0.1 -1,-0.1 2,-0.1 19,-0.1 0.373 93.1 62.5-105.8 2.4 -5.1 14.8 -5.8 36 56 A H S S+ 0 0 39 1,-0.1 -16,-2.4 19,-0.1 -1,-0.1 0.099 88.4 67.3-115.2 22.6 -1.5 13.9 -6.5 37 57 A I S S+ 0 0 2 -3,-0.3 2,-0.5 -18,-0.2 -28,-0.5 0.485 70.9 107.0-112.8 -14.3 -1.1 11.0 -4.0 38 58 A Q - 0 0 51 -30,-0.1 16,-1.4 -18,-0.1 2,-0.4 -0.566 54.0-171.6 -70.2 117.7 -3.5 8.7 -5.9 39 59 A L E -AG 7 53A 1 -32,-3.2 -32,-3.0 -2,-0.5 2,-0.5 -0.893 19.6-158.1-119.5 144.6 -1.4 6.0 -7.5 40 60 A Q E - G 0 52A 32 12,-2.4 12,-1.6 -2,-0.4 2,-0.4 -0.976 17.2-152.5-116.3 126.7 -2.3 3.3 -10.0 41 61 A L E - G 0 51A 11 -2,-0.5 2,-0.4 -38,-0.4 10,-0.2 -0.878 13.6-178.8-108.9 138.3 0.1 0.3 -10.1 42 62 A S E - G 0 50A 35 8,-1.6 8,-2.4 -2,-0.4 2,-0.5 -0.993 19.6-135.0-132.6 139.3 0.7 -1.9 -13.1 43 63 A A E - G 0 49A 9 364,-0.5 6,-0.3 -2,-0.4 366,-0.2 -0.817 15.7-176.8-100.3 125.5 3.0 -5.0 -13.5 44 64 A E E S- 0 0 70 4,-2.3 2,-0.3 -2,-0.5 -1,-0.2 0.847 82.6 -4.7 -80.7 -36.9 5.2 -5.4 -16.5 45 65 A S E > S- G 0 48A 41 3,-1.1 3,-2.0 392,-0.0 -1,-0.2 -0.859 106.5 -55.0-144.1 175.5 6.3 -8.8 -15.1 46 66 A V T 3 S- 0 0 81 1,-0.3 421,-0.2 -2,-0.3 3,-0.1 -0.399 127.5 -2.6 -57.1 122.1 5.7 -10.9 -12.1 47 67 A G T 3 S+ 0 0 10 359,-0.6 35,-2.0 419,-0.3 2,-0.6 0.460 108.1 110.0 74.1 0.7 6.8 -8.6 -9.2 48 68 A E E < -GH 45 81A 39 -3,-2.0 -4,-2.3 33,-0.2 -3,-1.1 -0.933 48.8-178.1-113.8 114.6 7.9 -5.7 -11.4 49 69 A V E -GH 43 80A 0 31,-2.6 31,-2.0 -2,-0.6 2,-0.3 -0.651 29.0-145.6-119.2 169.0 5.7 -2.6 -11.3 50 70 A Y E -G 42 0A 19 -8,-2.4 -8,-1.6 -2,-0.2 2,-0.4 -0.882 18.7-156.5-118.2 150.3 5.0 0.9 -12.6 51 71 A I E +G 41 0A 1 27,-0.4 9,-2.9 -2,-0.3 2,-0.3 -0.999 19.7 168.9-131.5 131.9 3.5 3.5 -10.3 52 72 A K E -GI 40 59A 49 -12,-1.6 -12,-2.4 -2,-0.4 7,-0.2 -0.994 35.0-107.3-153.8 151.1 1.6 6.5 -11.6 53 73 A S E > -G 39 0A 0 5,-1.9 4,-0.8 -2,-0.3 2,-0.3 -0.447 15.3-150.3 -70.5 133.8 -0.6 9.5 -10.8 54 74 A T T 4 S+ 0 0 53 -16,-1.4 -1,-0.1 -2,-0.2 -15,-0.1 -0.295 97.8 43.3 -96.1 45.3 -4.2 9.3 -11.8 55 75 A E T 4 S+ 0 0 115 -2,-0.3 -1,-0.2 -17,-0.1 -19,-0.1 0.327 128.5 20.9-152.7 -42.7 -4.2 13.1 -12.2 56 76 A T T 4 S- 0 0 43 2,-0.1 -2,-0.2 -36,-0.1 3,-0.1 0.376 90.9-137.1-114.1 -3.0 -1.0 13.9 -14.0 57 77 A G < + 0 0 24 -4,-0.8 2,-0.2 1,-0.2 -3,-0.1 0.783 50.7 153.1 50.6 28.6 -0.6 10.5 -15.4 58 78 A Q - 0 0 4 -38,-0.1 -5,-1.9 15,-0.0 2,-0.4 -0.593 41.8-130.0 -87.1 151.9 3.1 10.8 -14.5 59 79 A Y E -IJ 52 71A 43 12,-3.9 12,-3.1 -7,-0.2 -7,-0.2 -0.871 21.9-115.6-104.6 134.5 5.1 7.7 -13.8 60 80 A L E + J 0 70A 1 -9,-2.9 -9,-0.3 -2,-0.4 2,-0.3 -0.508 47.7 171.4 -65.9 129.5 7.3 7.5 -10.7 61 81 A A E - J 0 69A 0 8,-2.3 8,-2.3 -2,-0.2 2,-0.4 -0.947 28.2-145.9-141.0 162.0 10.9 7.3 -11.7 62 82 A M E - J 0 68A 1 15,-2.1 6,-0.2 -2,-0.3 34,-0.1 -0.964 16.4-147.6-134.7 118.7 14.4 7.4 -10.3 63 83 A D > - 0 0 30 4,-1.8 3,-1.2 -2,-0.4 34,-0.1 -0.062 40.0 -89.1 -74.3 178.3 17.4 8.9 -12.0 64 84 A T T 3 S+ 0 0 84 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.549 127.4 58.0 -65.1 -9.7 21.1 7.8 -11.8 65 85 A D T 3 S- 0 0 99 2,-0.1 -1,-0.3 50,-0.0 -3,-0.0 0.699 120.1-105.6 -92.4 -24.8 21.4 10.2 -8.9 66 86 A G S < S+ 0 0 0 -3,-1.2 49,-1.4 1,-0.3 2,-0.2 0.412 70.4 144.7 111.9 3.5 18.7 8.6 -6.8 67 87 A L - 0 0 60 47,-0.2 -4,-1.8 46,-0.1 2,-0.7 -0.539 44.3-139.4 -79.8 139.5 16.0 11.3 -7.3 68 88 A L E + J 0 62A 9 -2,-0.2 -42,-0.9 -42,-0.2 2,-0.3 -0.871 34.2 165.0 -99.1 115.2 12.4 10.4 -7.6 69 89 A Y E -EJ 25 61A 60 -8,-2.3 -8,-2.3 -2,-0.7 2,-0.8 -0.797 42.4-105.4-127.3 170.2 10.6 12.4 -10.3 70 90 A G E - J 0 60A 3 -46,-2.2 2,-0.4 -2,-0.3 -10,-0.2 -0.854 36.3-163.2 -99.6 104.6 7.4 12.3 -12.2 71 91 A S E - J 0 59A 12 -12,-3.1 -12,-3.9 -2,-0.8 -47,-0.1 -0.716 16.5-150.5 -89.9 136.4 8.1 11.1 -15.8 72 92 A Q S S+ 0 0 131 -2,-0.4 -1,-0.1 -14,-0.2 -48,-0.0 0.749 86.7 39.8 -75.8 -24.5 5.5 11.7 -18.5 73 93 A T S S- 0 0 90 -14,-0.1 -1,-0.2 -15,-0.0 -15,-0.0 -0.992 89.6-116.8-129.5 132.0 6.6 8.6 -20.4 74 94 A P + 0 0 45 0, 0.0 2,-0.3 0, 0.0 3,-0.1 -0.148 45.3 141.9 -62.5 157.3 7.5 5.2 -18.9 75 95 A N > - 0 0 69 1,-0.1 3,-2.3 -4,-0.0 4,-0.3 -0.945 65.7 -60.8-174.4-175.1 11.0 3.7 -19.3 76 96 A E G > S+ 0 0 134 1,-0.3 3,-2.5 -2,-0.3 20,-0.5 0.911 129.4 56.7 -51.6 -48.2 13.6 1.7 -17.4 77 97 A E G 3 S+ 0 0 28 1,-0.3 -15,-2.1 18,-0.1 -1,-0.3 0.567 101.5 63.2 -63.1 -3.5 14.0 4.4 -14.7 78 98 A C G < S+ 0 0 1 -3,-2.3 -27,-0.4 -17,-0.2 2,-0.4 0.463 83.8 94.0 -98.2 -6.0 10.2 3.9 -14.2 79 99 A L < - 0 0 14 -3,-2.5 16,-2.7 -4,-0.3 17,-0.5 -0.738 49.0-179.2 -95.4 141.2 10.4 0.3 -13.1 80 100 A F E -HK 49 94A 0 -31,-2.0 -31,-2.6 -2,-0.4 2,-0.8 -0.972 29.0-124.9-134.1 145.8 10.5 -0.9 -9.5 81 101 A L E -HK 48 93A 48 12,-2.4 12,-1.3 -2,-0.3 2,-0.5 -0.836 29.2-148.6 -93.2 114.8 10.6 -4.3 -7.9 82 102 A E E + K 0 92A 8 -35,-2.0 2,-0.4 -2,-0.8 10,-0.2 -0.729 20.4 179.0 -87.9 128.7 7.7 -4.6 -5.5 83 103 A R E - 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