==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-DEC-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE/LYASE INHIBITOR 22-NOV-10 3PO6 . COMPND 2 MOLECULE: CARBONIC ANHYDRASE 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR P.MADER,J.BRYNDA,R.GITTO,S.AGNELLO,S.FERRO,L.DE LUCA,D.VULLO . 258 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12004.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 164 63.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 57 22.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 25 9.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 33 12.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 17 6.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 2 2 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A H 0 0 244 0, 0.0 2,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -77.3 12.8 -1.0 6.4 2 4 A H - 0 0 56 1,-0.2 0, 0.0 0, 0.0 0, 0.0 -0.273 360.0 -62.2-100.9-174.8 9.9 0.2 8.6 3 5 A W + 0 0 53 -2,-0.1 2,-0.2 1,-0.1 -1,-0.2 -0.258 64.0 130.4 -68.1 153.9 7.6 -1.5 11.2 4 6 A G - 0 0 6 5,-2.7 10,-0.1 2,-0.2 -1,-0.1 -0.747 64.8 -74.7-166.4-142.5 5.3 -4.3 10.3 5 7 A Y S S+ 0 0 36 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.353 82.9 107.0-121.5 6.3 4.3 -7.8 11.5 6 8 A G S > S- 0 0 38 4,-0.1 4,-1.7 1,-0.1 3,-0.4 -0.148 83.7 -94.7 -81.8 178.9 7.3 -10.0 10.4 7 9 A K T 4 S+ 0 0 111 1,-0.2 -1,-0.1 2,-0.2 5,-0.1 0.854 124.6 38.7 -59.4 -36.7 10.1 -11.7 12.4 8 10 A H T 4 S+ 0 0 157 1,-0.1 -1,-0.2 4,-0.0 -3,-0.0 0.611 131.9 21.8 -99.0 -10.6 12.4 -8.9 11.7 9 11 A N T 4 S+ 0 0 56 -3,-0.4 -5,-2.7 -6,-0.1 -2,-0.2 0.224 95.8 116.8-136.7 16.7 10.1 -5.8 12.0 10 12 A G S >X S- 0 0 0 -4,-1.7 3,-2.6 -5,-0.2 4,-0.8 0.089 83.5 -66.1 -84.6-170.1 7.2 -7.1 14.1 11 13 A P G >4 S+ 0 0 25 0, 0.0 3,-0.5 0, 0.0 4,-0.4 0.749 127.0 60.4 -50.4 -32.3 5.8 -6.2 17.6 12 14 A E G 34 S+ 0 0 110 1,-0.2 -5,-0.1 2,-0.1 3,-0.0 0.603 109.7 44.6 -74.3 -13.4 8.9 -7.4 19.5 13 15 A H G X> S+ 0 0 51 -3,-2.6 3,-1.7 1,-0.1 4,-0.5 0.579 86.8 89.2 -98.5 -18.0 11.0 -4.9 17.6 14 16 A W H XX S+ 0 0 7 -4,-0.8 4,-2.4 -3,-0.5 3,-0.7 0.795 72.6 71.1 -59.7 -28.4 8.7 -1.8 17.8 15 17 A H H 34 S+ 0 0 65 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.752 86.6 66.5 -62.2 -23.7 10.1 -0.5 21.0 16 18 A K H <4 S+ 0 0 133 -3,-1.7 -1,-0.2 1,-0.2 -2,-0.2 0.923 117.0 23.9 -69.0 -41.0 13.4 0.5 19.4 17 19 A D H << S+ 0 0 131 -3,-0.7 -2,-0.2 -4,-0.5 -1,-0.2 0.706 136.6 36.6 -88.2 -22.0 11.7 3.2 17.3 18 20 A F >< - 0 0 57 -4,-2.4 3,-2.7 1,-0.1 -1,-0.2 -0.747 65.5-179.0-132.7 75.0 8.8 3.6 19.6 19 21 A P G > S+ 0 0 98 0, 0.0 3,-2.0 0, 0.0 -4,-0.1 0.735 75.6 76.1 -54.7 -23.1 9.9 3.3 23.2 20 22 A I G > S+ 0 0 66 1,-0.3 3,-2.6 179,-0.2 5,-0.2 0.658 71.0 89.4 -62.4 -10.5 6.4 3.8 24.6 21 23 A A G < S+ 0 0 6 -3,-2.7 -1,-0.3 1,-0.3 -6,-0.1 0.752 90.4 45.4 -53.8 -26.3 5.9 0.2 23.4 22 24 A K G < S+ 0 0 148 -3,-2.0 -1,-0.3 -4,-0.1 -2,-0.2 0.038 96.8 130.7-106.7 24.6 7.1 -0.8 26.9 23 25 A G S < S- 0 0 14 -3,-2.6 3,-0.5 1,-0.1 -3,-0.0 0.141 71.3-102.8 -74.5-176.3 4.8 1.9 28.6 24 26 A E S S+ 0 0 117 1,-0.2 226,-0.3 225,-0.1 -1,-0.1 0.569 112.5 35.8 -88.8 -12.5 2.3 1.8 31.4 25 27 A R S S+ 0 0 47 -5,-0.2 -1,-0.2 224,-0.1 2,-0.2 -0.278 79.4 154.5-139.5 54.0 -0.9 1.7 29.4 26 28 A Q - 0 0 2 -3,-0.5 220,-0.2 221,-0.4 170,-0.1 -0.489 33.0-101.7 -85.5 150.8 -0.2 -0.3 26.3 27 29 A S S S+ 0 0 0 168,-0.5 2,-0.2 -2,-0.2 -2,-0.0 -0.900 77.8 39.9-124.1 157.0 -2.8 -2.2 24.3 28 30 A P + 0 0 0 0, 0.0 218,-2.7 0, 0.0 2,-0.3 0.584 66.5 176.6 -78.5-179.6 -4.1 -4.8 23.6 29 31 A V - 0 0 1 216,-0.3 77,-1.3 -2,-0.2 2,-0.4 -0.921 36.1 -98.3-136.4 162.6 -4.5 -6.7 26.8 30 32 A D E -a 106 0A 32 216,-0.4 2,-0.8 -2,-0.3 77,-0.2 -0.731 33.7-139.9 -76.9 133.8 -5.9 -10.0 28.0 31 33 A I E -a 107 0A 0 75,-3.1 77,-2.7 -2,-0.4 2,-1.0 -0.854 10.3-158.7 -99.9 102.4 -9.4 -9.5 29.5 32 34 A D > - 0 0 67 -2,-0.8 4,-2.0 75,-0.2 3,-0.4 -0.802 3.8-160.9 -82.9 107.5 -9.6 -11.7 32.5 33 35 A T T 4 S+ 0 0 44 -2,-1.0 -1,-0.2 1,-0.2 222,-0.0 0.730 86.4 53.5 -66.9 -25.6 -13.4 -12.0 32.9 34 36 A H T 4 S+ 0 0 163 1,-0.1 -1,-0.2 -3,-0.1 -2,-0.0 0.863 112.9 42.3 -77.8 -32.8 -13.3 -13.1 36.5 35 37 A T T 4 S+ 0 0 110 -3,-0.4 -2,-0.2 2,-0.1 -1,-0.1 0.732 90.3 99.3 -84.7 -26.7 -11.1 -10.2 37.6 36 38 A A < - 0 0 16 -4,-2.0 2,-0.5 218,-0.1 218,-0.2 -0.385 69.6-140.6 -58.7 135.9 -13.0 -7.5 35.6 37 39 A K E -c 254 0B 143 216,-1.8 218,-2.4 -2,-0.1 2,-0.1 -0.866 10.6-116.1-110.2 134.2 -15.4 -5.7 37.9 38 40 A Y E -c 255 0B 98 -2,-0.5 218,-0.2 216,-0.2 220,-0.1 -0.411 30.3-153.9 -54.4 133.0 -18.9 -4.6 37.2 39 41 A D > - 0 0 32 216,-2.6 3,-1.1 1,-0.1 -1,-0.1 -0.930 16.2-171.3-118.5 107.9 -19.0 -0.8 37.4 40 42 A P T 3 S+ 0 0 98 0, 0.0 -1,-0.1 0, 0.0 216,-0.0 0.657 83.5 70.3 -72.0 -12.7 -22.4 0.8 38.3 41 43 A S T 3 S+ 0 0 90 2,-0.1 2,-0.2 40,-0.0 -2,-0.0 0.668 73.4 107.7 -74.7 -16.3 -21.0 4.3 37.6 42 44 A L < - 0 0 31 -3,-1.1 3,-0.1 213,-0.2 38,-0.0 -0.462 65.2-143.4 -65.3 127.2 -20.9 3.5 33.8 43 45 A K - 0 0 71 37,-1.5 37,-0.3 -2,-0.2 39,-0.1 -0.380 39.5 -74.5 -81.7 166.5 -23.6 5.4 32.0 44 46 A P - 0 0 119 0, 0.0 36,-0.8 0, 0.0 2,-0.3 -0.381 51.0-115.3 -67.1 148.0 -25.4 3.7 29.1 45 47 A L E -D 79 0B 24 34,-0.3 2,-0.5 141,-0.1 34,-0.2 -0.638 26.6-159.0 -83.5 137.6 -23.3 3.4 25.8 46 48 A S E -D 78 0B 38 32,-3.1 32,-2.3 -2,-0.3 2,-0.6 -0.961 12.1-178.3-124.5 110.5 -24.6 5.3 22.8 47 49 A V E -D 77 0B 31 -2,-0.5 2,-0.6 30,-0.2 30,-0.2 -0.948 6.7-179.2-109.2 108.8 -23.6 4.3 19.3 48 50 A S E +D 76 0B 45 28,-2.9 28,-1.9 -2,-0.6 3,-0.2 -0.770 21.3 146.0-117.6 86.3 -25.2 6.7 16.9 49 51 A Y > + 0 0 3 -2,-0.6 3,-1.7 26,-0.2 130,-0.2 0.229 32.2 110.3-105.4 8.7 -24.2 5.7 13.3 50 52 A D T 3 S+ 0 0 98 1,-0.3 -1,-0.2 24,-0.2 25,-0.1 0.809 86.4 38.6 -57.1 -33.2 -27.4 6.6 11.3 51 53 A Q T 3 S+ 0 0 125 23,-0.3 24,-0.3 -3,-0.2 -1,-0.3 0.181 82.8 144.5-104.5 17.0 -25.8 9.6 9.5 52 54 A A < - 0 0 22 -3,-1.7 2,-0.5 22,-0.2 18,-0.1 -0.285 33.9-159.1 -58.6 135.1 -22.3 7.9 9.0 53 55 A T - 0 0 46 16,-0.3 16,-2.9 122,-0.1 2,-0.1 -0.894 4.0-161.7-122.6 99.1 -20.8 8.9 5.6 54 56 A S E +E 68 0B 0 -2,-0.5 121,-0.6 122,-0.3 14,-0.3 -0.433 12.6 174.8 -74.2 153.2 -18.1 6.5 4.4 55 57 A L E - 0 0 77 12,-3.3 118,-2.3 1,-0.4 2,-0.3 0.718 50.3 -6.8-122.1 -46.8 -15.8 7.7 1.7 56 58 A R E -EF 67 172B 82 11,-1.0 11,-3.0 116,-0.3 -1,-0.4 -0.983 45.9-134.9-158.2 153.8 -13.0 5.4 0.8 57 59 A I E -EF 66 171B 0 114,-2.3 114,-2.1 -2,-0.3 2,-0.4 -0.978 27.2-169.9-120.6 135.5 -11.2 2.1 1.6 58 60 A L E -EF 65 170B 34 7,-2.2 7,-2.8 -2,-0.4 2,-0.7 -0.987 23.6-145.9-131.8 132.1 -7.4 2.1 1.7 59 61 A N E -E 64 0B 0 110,-2.8 109,-2.7 -2,-0.4 5,-0.2 -0.899 21.1-178.8 -88.8 112.3 -4.8 -0.7 1.9 60 62 A N - 0 0 59 3,-1.9 4,-0.1 -2,-0.7 -1,-0.1 0.246 53.0-100.2 -99.5 11.5 -2.1 1.0 3.9 61 63 A G S S+ 0 0 7 2,-0.5 3,-0.1 166,-0.2 106,-0.1 0.383 118.4 55.6 87.0 -4.5 0.3 -2.0 3.9 62 64 A H S S- 0 0 42 1,-0.6 2,-0.2 -58,-0.1 -1,-0.1 0.608 122.7 -31.3-121.6 -42.0 -0.8 -3.0 7.5 63 65 A A S S- 0 0 6 -5,-0.1 -3,-1.9 31,-0.1 -1,-0.6 -0.818 71.2 -86.2-155.3-169.5 -4.5 -3.4 7.2 64 66 A F E -E 59 0B 0 29,-0.3 29,-0.5 -2,-0.2 2,-0.5 -0.976 36.4-153.8-113.9 140.5 -7.4 -1.9 5.2 65 67 A N E -EG 58 92B 25 -7,-2.8 -7,-2.2 -2,-0.4 2,-0.6 -0.948 8.2-154.5-115.1 126.6 -9.1 1.2 6.5 66 68 A V E -EG 57 91B 0 25,-2.9 25,-2.1 -2,-0.5 2,-0.3 -0.890 27.4-151.8 -96.2 117.3 -12.7 2.3 5.7 67 69 A E E -EG 56 90B 43 -11,-3.0 -12,-3.3 -2,-0.6 -11,-1.0 -0.711 9.3-157.5-102.5 144.2 -12.6 6.1 6.1 68 70 A F E -E 54 0B 10 21,-2.6 2,-0.8 -2,-0.3 -14,-0.2 -0.856 28.8-107.4-119.5 150.6 -15.5 8.3 7.1 69 71 A D + 0 0 39 -16,-2.9 -16,-0.3 -2,-0.3 3,-0.3 -0.710 39.3 173.7 -72.8 109.4 -16.2 12.0 6.6 70 72 A D + 0 0 44 -2,-0.8 -1,-0.1 1,-0.2 17,-0.1 -0.032 46.7 105.2-108.9 26.7 -15.6 13.4 10.1 71 73 A S S S+ 0 0 84 2,-0.0 2,-0.3 56,-0.0 -1,-0.2 0.504 83.3 39.8 -83.6 -10.2 -16.1 17.1 9.2 72 74 A Q S S- 0 0 111 -3,-0.3 2,-1.4 3,-0.0 3,-0.2 -0.929 98.2 -95.4-135.4 163.4 -19.5 17.2 10.8 73 75 A D S S+ 0 0 111 -2,-0.3 3,-0.1 1,-0.2 -3,-0.1 -0.653 79.1 119.2 -83.0 90.1 -21.1 15.7 13.9 74 76 A K + 0 0 48 -2,-1.4 2,-0.7 1,-0.3 -23,-0.3 0.597 63.6 31.5-117.1 -86.4 -22.6 12.6 12.3 75 77 A A S S+ 0 0 5 -24,-0.3 13,-2.7 -3,-0.2 2,-0.3 -0.749 80.5 168.0 -86.3 113.0 -21.5 9.2 13.4 76 78 A V E -DH 48 87B 9 -28,-1.9 -28,-2.9 -2,-0.7 2,-0.4 -0.937 33.3-148.4-135.9 151.4 -20.7 9.4 17.2 77 79 A L E +DH 47 86B 0 9,-2.9 9,-2.3 -2,-0.3 2,-0.3 -0.970 31.9 154.2-114.9 129.9 -19.9 7.4 20.2 78 80 A K E +D 46 0B 93 -32,-2.3 -32,-3.1 -2,-0.4 7,-0.1 -0.890 33.6 35.2-143.7 172.7 -21.0 8.7 23.7 79 81 A G E > S+D 45 0B 19 5,-0.5 3,-2.3 3,-0.3 -34,-0.3 -0.249 73.2 80.4 77.8-161.3 -21.9 7.4 27.1 80 82 A G T 3 S- 0 0 5 -36,-0.8 -37,-1.5 -37,-0.3 -1,-0.2 -0.440 122.3 -19.8 60.1-130.0 -20.4 4.4 28.8 81 83 A P T 3 S+ 0 0 40 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.547 115.9 109.3 -80.6 -4.8 -17.1 5.4 30.3 82 84 A L < - 0 0 12 -3,-2.3 2,-0.5 -39,-0.1 -3,-0.3 -0.471 55.6-153.0 -86.6 142.2 -16.8 8.5 28.0 83 85 A D - 0 0 137 -2,-0.2 2,-0.1 53,-0.1 -1,-0.0 -0.933 69.0 -12.8-105.0 127.8 -17.2 12.1 28.8 84 86 A G S S- 0 0 53 -2,-0.5 -5,-0.5 38,-0.1 2,-0.4 -0.390 101.0 -38.9 79.7-155.6 -18.4 14.1 25.9 85 87 A T - 0 0 42 -7,-0.1 38,-2.5 -2,-0.1 2,-0.4 -0.907 41.2-162.9-121.5 132.6 -18.7 13.1 22.2 86 88 A Y E -HI 77 122B 3 -9,-2.3 -9,-2.9 -2,-0.4 2,-0.4 -0.962 15.1-142.8-118.8 130.4 -16.3 11.0 20.1 87 89 A R E -HI 76 121B 41 34,-2.9 34,-2.0 -2,-0.4 -11,-0.2 -0.765 17.5-117.9 -99.3 133.3 -16.6 11.1 16.3 88 90 A L E + I 0 120B 2 -13,-2.7 32,-0.3 -2,-0.4 -13,-0.2 -0.428 38.0 163.9 -66.8 128.1 -16.1 8.1 14.0 89 91 A I E - 0 0 34 30,-2.7 -21,-2.6 1,-0.4 2,-0.3 0.717 59.5 -26.1-112.5 -35.8 -13.1 8.6 11.7 90 92 A Q E -GI 67 119B 32 29,-1.2 29,-3.0 -23,-0.2 -1,-0.4 -0.986 46.5-140.2-166.8 162.5 -12.4 5.1 10.4 91 93 A F E +GI 66 118B 0 -25,-2.1 -25,-2.9 -2,-0.3 2,-0.3 -0.967 22.4 161.6-131.0 159.4 -12.6 1.4 11.0 92 94 A H E -GI 65 117B 25 25,-1.8 25,-3.0 -2,-0.3 2,-0.3 -0.935 23.1-127.4-157.3 174.1 -10.2 -1.5 10.3 93 95 A F E - I 0 116B 0 -29,-0.5 2,-0.4 -2,-0.3 -29,-0.3 -0.857 0.4-148.9-128.2 160.8 -9.6 -5.1 11.3 94 96 A H E + I 0 115B 3 21,-2.1 21,-2.2 -2,-0.3 2,-0.3 -0.983 31.8 167.9-122.9 139.5 -6.8 -7.3 12.6 95 97 A W E - I 0 114B 0 -2,-0.4 146,-1.2 19,-0.2 145,-0.9 -0.946 23.7-117.9-151.4 169.5 -6.9 -10.9 11.6 96 98 A G - 0 0 0 17,-1.4 6,-0.1 5,-0.6 3,-0.1 -0.441 23.5-120.2-105.3 176.9 -5.0 -14.2 11.5 97 99 A S S S+ 0 0 42 142,-0.2 2,-0.3 -2,-0.1 5,-0.1 0.590 105.6 29.9 -84.6 -16.9 -3.5 -16.7 9.1 98 100 A L S > S- 0 0 114 3,-0.3 3,-1.6 15,-0.1 -2,-0.2 -0.948 90.4-109.7-140.2 159.1 -5.8 -19.4 10.7 99 101 A D T 3 S+ 0 0 68 -2,-0.3 48,-0.1 1,-0.3 15,-0.1 0.748 110.4 68.8 -67.3 -22.6 -9.1 -19.1 12.5 100 102 A G T 3 S+ 0 0 57 13,-0.1 2,-0.3 2,-0.1 -1,-0.3 0.390 106.5 31.2 -78.2 5.4 -7.5 -19.8 15.9 101 103 A Q < + 0 0 62 -3,-1.6 -5,-0.6 12,-0.1 -3,-0.3 -0.971 65.7 94.9-153.6 164.5 -5.7 -16.4 16.0 102 104 A G + 0 0 0 1,-0.5 13,-0.3 -2,-0.3 11,-0.2 0.034 55.1 107.0 142.0 -33.7 -6.1 -12.9 14.8 103 105 A S - 0 0 1 9,-2.0 -1,-0.5 11,-0.3 139,-0.1 -0.410 52.2-152.6 -73.0 157.8 -7.6 -10.8 17.6 104 106 A E S S+ 0 0 1 -10,-0.1 -1,-0.1 -3,-0.1 2,-0.1 0.865 83.0 53.7 -91.6 -59.8 -5.5 -8.4 19.5 105 107 A H S S- 0 0 0 -77,-0.1 7,-0.5 140,-0.1 2,-0.3 -0.490 77.0-157.6 -66.8 151.1 -7.5 -8.4 22.8 106 108 A T E -a 30 0A 8 -77,-1.3 -75,-3.1 5,-0.1 2,-0.5 -0.894 11.0-139.4-126.9 161.0 -8.1 -11.9 24.2 107 109 A V E > S-aB 31 110A 16 3,-1.7 3,-2.3 -2,-0.3 -75,-0.2 -0.970 89.3 -19.7-126.4 110.5 -10.8 -13.0 26.7 108 110 A D T 3 S- 0 0 71 -77,-2.7 -1,-0.2 -2,-0.5 -76,-0.1 0.915 129.1 -55.0 51.2 42.7 -9.4 -15.4 29.3 109 111 A K T 3 S+ 0 0 158 1,-0.2 2,-0.3 -78,-0.1 -1,-0.3 0.338 105.2 140.6 71.5 -2.8 -6.5 -15.9 26.9 110 112 A K B < -B 107 0A 112 -3,-2.3 -3,-1.7 -9,-0.0 2,-0.4 -0.552 41.1-150.4 -69.7 126.0 -8.9 -16.9 24.1 111 113 A K - 0 0 92 -2,-0.3 2,-0.2 -11,-0.3 -5,-0.1 -0.862 7.8-149.1 -94.3 130.3 -7.9 -15.5 20.6 112 114 A Y - 0 0 30 -7,-0.5 -9,-2.0 -2,-0.4 34,-0.2 -0.496 28.1-106.9 -90.0 169.8 -10.7 -14.8 18.2 113 115 A A S S- 0 0 3 32,-1.1 -17,-1.4 -11,-0.2 2,-0.3 0.762 93.5 -14.6 -68.1 -26.9 -10.3 -15.0 14.4 114 116 A A E -IJ 95 145B 0 31,-1.3 31,-2.5 -19,-0.2 2,-0.3 -0.981 58.1-136.9-165.5 170.6 -10.3 -11.3 14.0 115 117 A E E -IJ 94 144B 0 -21,-2.2 -21,-2.1 -2,-0.3 2,-0.4 -0.977 11.3-146.7-147.4 129.3 -11.1 -8.0 15.7 116 118 A L E -IJ 93 143B 0 27,-2.9 27,-2.3 -2,-0.3 2,-0.5 -0.819 10.8-161.3 -93.9 133.5 -12.8 -4.9 14.3 117 119 A H E -IJ 92 142B 2 -25,-3.0 -25,-1.8 -2,-0.4 2,-0.7 -0.971 4.9-166.7-121.3 113.4 -11.7 -1.4 15.6 118 120 A L E -IJ 91 141B 0 23,-2.6 23,-2.6 -2,-0.5 2,-0.5 -0.919 21.2-150.5 -97.6 112.7 -14.1 1.5 15.1 119 121 A V E +IJ 90 140B 10 -29,-3.0 -30,-2.7 -2,-0.7 -29,-1.2 -0.788 19.6 175.4 -98.8 130.1 -11.9 4.5 15.8 120 122 A H E -IJ 88 139B 0 19,-1.9 19,-2.4 -2,-0.5 2,-0.4 -0.971 16.0-146.7-133.1 145.8 -13.3 7.7 17.2 121 123 A W E -IJ 87 138B 9 -34,-2.0 -34,-2.9 -2,-0.3 2,-0.5 -0.898 27.9-105.7-119.2 147.8 -11.8 11.0 18.4 122 124 A N E > -I 86 0B 3 15,-3.0 3,-2.2 -2,-0.4 -36,-0.2 -0.486 23.0-147.6 -70.7 117.1 -12.9 13.4 21.1 123 125 A T G > S+ 0 0 46 -38,-2.5 3,-1.5 -2,-0.5 -1,-0.2 0.695 90.3 76.9 -65.8 -17.0 -14.4 16.4 19.5 124 127 A K G 3 S+ 0 0 147 -39,-0.3 -1,-0.3 1,-0.3 -38,-0.1 0.722 93.3 53.7 -64.0 -19.8 -13.1 18.6 22.4 125 128 A Y G < S- 0 0 54 -3,-2.2 2,-1.4 12,-0.1 -1,-0.3 0.365 104.0-130.7 -99.5 1.5 -9.7 18.4 20.7 126 129 A G S < S+ 0 0 54 -3,-1.5 2,-0.3 -4,-0.2 -3,-0.1 -0.074 72.7 15.2 86.2 -43.4 -10.8 19.6 17.3 127 130 A D S > S- 0 0 84 -2,-1.4 4,-2.4 -5,-0.2 3,-0.2 -0.975 80.6 -97.4-158.0 175.4 -9.3 16.9 15.1 128 131 A F H > S+ 0 0 68 -2,-0.3 4,-2.2 1,-0.2 5,-0.2 0.884 114.5 54.6 -61.2 -45.5 -7.7 13.5 15.2 129 132 A G H 4 S+ 0 0 41 1,-0.2 4,-0.2 2,-0.2 -1,-0.2 0.847 114.0 42.0 -63.5 -32.1 -4.0 14.6 15.2 130 133 A K H >4 S+ 0 0 55 -3,-0.2 3,-1.2 -5,-0.2 -1,-0.2 0.869 111.1 57.8 -75.5 -39.4 -4.5 16.8 18.3 131 134 A A H >< S+ 0 0 0 -4,-2.4 3,-2.0 1,-0.2 6,-0.2 0.889 97.3 59.6 -60.2 -38.4 -6.7 14.2 19.9 132 135 A V T 3< S+ 0 0 19 -4,-2.2 -1,-0.2 1,-0.3 -2,-0.1 0.667 96.9 63.1 -70.7 -9.8 -4.0 11.4 19.8 133 136 A Q T < S+ 0 0 144 -3,-1.2 -1,-0.3 -4,-0.2 -2,-0.2 0.341 95.3 77.3 -89.1 7.6 -1.7 13.7 21.9 134 137 A Q S X S- 0 0 60 -3,-2.0 3,-1.7 69,-0.1 4,-0.3 -0.910 81.3-128.7-120.2 146.1 -4.2 13.5 24.8 135 138 A P T 3 S+ 0 0 83 0, 0.0 3,-0.2 0, 0.0 58,-0.2 0.791 114.6 34.6 -64.8 -24.0 -4.9 10.7 27.4 136 139 A D T 3 S+ 0 0 54 1,-0.1 68,-0.1 56,-0.1 -14,-0.1 -0.162 87.4 114.3-116.6 34.4 -8.6 10.8 26.6 137 140 A G S < S+ 0 0 0 -3,-1.7 -15,-3.0 -6,-0.2 2,-0.3 0.825 71.4 35.0 -74.2 -37.1 -8.3 11.6 22.9 138 141 A L E -Jk 121 204B 1 65,-2.7 67,-2.6 -4,-0.3 2,-0.4 -0.900 53.1-161.3-123.0 154.8 -9.6 8.5 21.3 139 142 A A E -Jk 120 205B 0 -19,-2.4 -19,-1.9 -2,-0.3 2,-0.5 -0.994 14.6-166.2-128.7 121.9 -12.3 5.9 21.9 140 143 A V E -Jk 119 206B 6 65,-1.8 67,-2.6 -2,-0.4 2,-0.7 -0.961 8.8-152.9-113.9 123.6 -11.9 2.6 20.1 141 144 A L E -Jk 118 207B 0 -23,-2.6 -23,-2.6 -2,-0.5 2,-0.4 -0.874 17.1-160.6 -93.7 114.6 -14.9 0.3 19.9 142 145 A G E -Jk 117 208B 0 65,-2.8 67,-2.8 -2,-0.7 2,-0.4 -0.849 10.3-175.9-104.9 133.5 -13.5 -3.3 19.6 143 146 A I E -J 116 0B 0 -27,-2.3 -27,-2.9 -2,-0.4 2,-0.2 -0.995 19.2-133.9-133.3 124.9 -15.6 -6.1 18.3 144 147 A F E -J 115 0B 0 65,-0.4 69,-2.9 -2,-0.4 2,-0.4 -0.514 13.7-148.8 -76.6 147.8 -14.5 -9.7 18.1 145 148 A L E -Jl 114 213B 1 -31,-2.5 -31,-1.3 67,-0.2 -32,-1.1 -0.971 13.0-175.1-116.9 131.5 -15.1 -11.9 15.0 146 149 A K E - l 0 214B 95 67,-2.4 69,-2.7 -2,-0.4 2,-0.6 -0.872 30.6-110.4-115.7 155.3 -15.6 -15.6 15.1 147 150 A V E S+ l 0 215B 43 -2,-0.3 69,-0.2 67,-0.2 2,-0.2 -0.754 75.6 83.5 -90.6 123.0 -16.0 -17.9 12.1 148 151 A G S S+ 0 0 42 67,-3.0 69,-0.4 -2,-0.6 2,-0.1 -0.542 79.7 22.3-171.1-115.0 -19.4 -19.3 11.6 149 152 A S S S- 0 0 94 -2,-0.2 -1,-0.4 67,-0.1 -3,-0.1 -0.396 87.1-100.0 -69.6 144.5 -22.5 -17.8 9.9 150 153 A A - 0 0 57 65,-0.3 65,-0.2 -3,-0.1 64,-0.1 -0.375 23.4-131.4 -61.5 147.3 -21.8 -15.0 7.4 151 154 A K >> - 0 0 39 1,-0.2 3,-1.8 65,-0.1 4,-0.6 -0.895 15.4-161.6 -98.8 103.5 -22.2 -11.4 8.4 152 155 A P G >4 S+ 0 0 112 0, 0.0 3,-1.5 0, 0.0 4,-0.4 0.898 87.2 59.9 -59.6 -32.3 -24.3 -9.9 5.6 153 156 A G G 34 S+ 0 0 26 27,-0.5 4,-0.2 1,-0.3 27,-0.2 0.601 102.5 54.5 -71.5 -12.2 -23.3 -6.3 6.6 154 157 A L G X> S+ 0 0 1 -3,-1.8 4,-2.0 26,-0.2 3,-0.7 0.613 83.6 85.6 -86.4 -16.7 -19.7 -7.2 6.0 155 158 A Q H S+ 0 0 153 -4,-0.4 4,-0.7 1,-0.2 -1,-0.3 0.895 109.4 46.8 -63.5 -34.6 -19.8 -5.0 0.8 157 160 A V H X> S+ 0 0 0 -3,-0.7 3,-1.1 -4,-0.2 4,-0.7 0.959 111.6 50.0 -66.8 -49.0 -16.4 -4.7 2.4 158 161 A V H >< S+ 0 0 5 -4,-2.0 3,-1.0 1,-0.3 4,-0.4 0.891 107.7 54.3 -57.0 -39.2 -15.3 -8.2 1.4 159 162 A D H 3< S+ 0 0 90 -4,-2.7 -1,-0.3 1,-0.3 3,-0.2 0.697 105.3 52.1 -78.5 -14.4 -16.3 -7.6 -2.2 160 163 A V H X< S+ 0 0 23 -3,-1.1 3,-1.5 -4,-0.7 4,-0.3 0.569 86.0 87.1 -89.5 -11.6 -14.2 -4.4 -2.7 161 164 A L G X< S+ 0 0 7 -3,-1.0 3,-1.6 -4,-0.7 -1,-0.2 0.810 76.3 65.1 -63.7 -31.7 -11.0 -6.0 -1.4 162 165 A D G > S+ 0 0 133 -4,-0.4 3,-0.6 1,-0.3 -1,-0.3 0.790 99.7 55.3 -57.7 -27.6 -10.0 -7.4 -4.8 163 166 A S G < S+ 0 0 38 -3,-1.5 -1,-0.3 1,-0.2 -2,-0.2 0.492 112.2 40.2 -86.7 -5.5 -9.7 -3.8 -5.9 164 167 A I G < S+ 0 0 0 -3,-1.6 63,-0.3 -4,-0.3 -1,-0.2 -0.243 71.4 140.7-129.9 46.6 -7.2 -2.8 -3.1 165 168 A K < + 0 0 75 -3,-0.6 62,-2.7 61,-0.1 2,-0.2 0.856 60.6 46.7 -60.2 -38.5 -5.1 -5.9 -3.1 166 169 A T S > S- 0 0 12 60,-0.2 3,-2.1 1,-0.1 -107,-0.3 -0.695 97.1 -76.4-117.2 159.6 -1.8 -4.1 -2.5 167 170 A K T 3 S+ 0 0 105 62,-2.2 64,-0.5 1,-0.3 -107,-0.2 -0.205 114.1 21.0 -51.3 127.7 -0.2 -1.4 -0.4 168 171 A G T 3 S+ 0 0 56 -109,-2.7 2,-0.3 1,-0.3 -1,-0.3 0.188 90.7 125.8 97.0 -16.3 -1.2 2.1 -1.4 169 172 A K < + 0 0 79 -3,-2.1 -110,-2.8 -110,-0.1 -1,-0.3 -0.593 33.4 178.7 -79.4 137.6 -4.3 1.1 -3.3 170 173 A S E -F 58 0B 55 -2,-0.3 2,-0.3 -112,-0.2 -112,-0.2 -0.910 9.4-164.5-129.2 160.4 -7.6 2.8 -2.5 171 174 A A E -F 57 0B 21 -114,-2.1 -114,-2.3 -2,-0.3 2,-0.0 -0.990 35.5 -94.2-140.7 149.1 -11.2 2.6 -3.9 172 175 A D E +F 56 0B 146 -2,-0.3 -116,-0.3 -116,-0.2 -117,-0.1 -0.421 42.0 177.7 -58.5 140.3 -14.4 4.7 -3.5 173 176 A F + 0 0 18 -118,-2.3 3,-0.4 -106,-0.1 -117,-0.2 -0.481 12.9 158.4-150.3 68.8 -16.4 3.3 -0.7 174 177 A T + 0 0 85 1,-0.2 -119,-0.2 -119,-0.2 -121,-0.1 -0.526 54.0 24.9 -92.1 160.2 -19.5 5.4 -0.2 175 178 A N S S+ 0 0 142 -121,-0.6 2,-0.5 1,-0.2 -1,-0.2 0.726 73.7 151.2 63.4 28.3 -22.8 4.6 1.5 176 179 A F - 0 0 9 -3,-0.4 -122,-0.3 -20,-0.0 -1,-0.2 -0.830 36.0-148.1 -90.7 129.1 -21.4 1.9 3.7 177 180 A D > - 0 0 67 -2,-0.5 3,-1.6 1,-0.1 4,-0.1 -0.837 7.7-163.3-102.3 108.9 -23.4 1.6 7.0 178 181 A P G > S+ 0 0 0 0, 0.0 3,-2.2 0, 0.0 4,-0.2 0.671 78.7 82.9 -72.6 -6.9 -21.3 0.5 9.9 179 182 A R G > S+ 0 0 122 1,-0.3 3,-1.2 -130,-0.2 -26,-0.1 0.768 80.7 66.4 -60.4 -30.0 -24.4 -0.5 11.9 180 183 A G G < S+ 0 0 31 -3,-1.6 -27,-0.5 1,-0.2 -1,-0.3 0.491 93.6 59.9 -69.3 -4.8 -24.4 -3.8 10.0 181 184 A L G < S+ 0 0 0 -3,-2.2 -1,-0.2 -28,-0.1 -2,-0.2 0.398 86.3 98.4 -98.3 -2.7 -21.1 -4.7 11.7 182 185 A L < - 0 0 30 -3,-1.2 2,-0.1 -4,-0.2 -29,-0.1 -0.587 67.9-129.8 -89.5 147.1 -22.5 -4.6 15.3 183 186 A P - 0 0 13 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.334 32.6-101.7 -77.9 174.7 -23.6 -7.5 17.4 184 187 A E S S+ 0 0 186 -2,-0.1 2,-0.3 2,-0.0 29,-0.0 0.927 101.9 59.0 -61.5 -50.1 -27.0 -7.5 19.2 185 188 A S - 0 0 35 1,-0.1 26,-0.3 2,-0.1 24,-0.0 -0.656 58.1-162.0 -91.2 142.9 -25.6 -6.7 22.7 186 189 A L + 0 0 63 -2,-0.3 -1,-0.1 23,-0.1 -141,-0.1 0.204 44.6 138.0-102.8 13.7 -23.6 -3.6 23.7 187 190 A D + 0 0 67 22,-0.1 23,-2.4 68,-0.0 24,-0.5 -0.383 34.9 172.0 -53.5 138.8 -22.3 -5.2 26.9 188 191 A Y E -M 209 0B 6 21,-0.3 68,-2.7 22,-0.1 2,-0.3 -0.933 39.1-131.9-149.8 163.6 -18.6 -4.3 27.1 189 192 A W E -MN 208 255B 7 19,-2.4 19,-2.9 -2,-0.3 2,-0.3 -0.887 29.3-166.1-110.1 149.8 -15.4 -4.1 29.0 190 193 A T E +MN 207 254B 9 64,-2.5 64,-2.5 -2,-0.3 17,-0.2 -0.997 16.9 152.8-141.5 146.8 -13.4 -0.9 29.2 191 194 A Y E -M 206 0B 5 15,-1.4 15,-2.5 -2,-0.3 2,-0.4 -0.971 45.9 -96.9-162.9 155.2 -9.9 0.1 30.2 192 195 A P E +M 205 0B 51 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.731 61.6 131.1 -81.5 132.8 -7.4 2.9 29.4 193 196 A G E -M 204 0B 0 11,-3.1 11,-1.8 -2,-0.4 2,-0.3 -0.535 41.6 -90.4-153.2-146.1 -4.8 1.9 26.8 194 197 A S - 0 0 0 8,-0.2 8,-0.2 9,-0.2 7,-0.1 -0.819 43.8 -74.0-137.9 170.9 -3.1 2.8 23.6 195 198 A L - 0 0 29 6,-2.2 -168,-0.5 -2,-0.3 9,-0.1 -0.475 40.6-140.1 -60.3 146.3 -3.0 2.6 19.8 196 199 A T S S+ 0 0 7 -2,-0.1 -1,-0.1 -170,-0.1 47,-0.0 0.401 82.5 54.6 -98.7 2.6 -2.0 -1.0 18.9 197 200 A T S > S- 0 0 41 4,-0.1 3,-2.9 45,-0.0 4,-0.3 -0.920 103.3 -45.3-122.0 155.7 0.3 0.1 16.0 198 201 A P T 3 S+ 0 0 10 0, 0.0 -2,-0.1 0, 0.0 -180,-0.0 -0.319 124.9 43.7 -45.8 138.5 3.1 2.6 16.0 199 202 A P T 3 S- 0 0 58 0, 0.0 -179,-0.2 0, 0.0 -178,-0.0 -0.973 84.2-161.8 -84.1 10.0 3.2 5.2 17.3 200 203 A L < - 0 0 0 -3,-2.9 -173,-0.1 1,-0.2 -4,-0.0 0.752 19.4-174.0 62.6 28.0 1.6 3.3 20.1 201 204 A L - 0 0 60 -4,-0.3 -6,-2.2 -7,-0.1 2,-1.7 -0.238 29.5-127.1 -63.6 140.9 0.3 6.5 21.7 202 205 A E S S+ 0 0 47 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.511 76.5 108.9 -90.6 70.2 -1.4 6.2 25.1 203 206 A C + 0 0 1 -2,-1.7 -65,-2.7 -67,-0.1 2,-0.4 0.158 46.0 106.8-132.2 13.1 -4.5 8.1 24.2 204 207 A V E -kM 138 193B 0 -11,-1.8 -11,-3.1 -3,-0.2 2,-0.7 -0.879 49.2-157.9-114.6 130.7 -7.3 5.5 23.9 205 208 A T E -kM 139 192B 26 -67,-2.6 -65,-1.8 -2,-0.4 2,-0.4 -0.930 32.4-147.9 -90.4 112.4 -10.3 4.6 26.0 206 209 A W E -kM 140 191B 4 -15,-2.5 -15,-1.4 -2,-0.7 2,-0.4 -0.731 19.9-176.1 -85.5 135.1 -10.9 1.0 24.9 207 210 A I E -kM 141 190B 0 -67,-2.6 -65,-2.8 -2,-0.4 2,-0.5 -0.960 8.2-173.2-130.2 110.3 -14.5 -0.3 24.8 208 211 A V E -kM 142 189B 0 -19,-2.9 -19,-2.4 -2,-0.4 -65,-0.2 -0.925 19.3-132.4-114.5 117.3 -14.5 -4.0 23.9 209 212 A L E - M 0 188B 0 -67,-2.8 -65,-0.4 -2,-0.5 -21,-0.3 -0.473 3.2-145.6 -70.0 142.4 -17.8 -5.7 23.3 210 213 A K S S+ 0 0 98 -23,-2.4 -1,-0.1 -2,-0.2 -22,-0.1 0.862 81.4 73.5 -72.1 -39.3 -18.4 -9.0 24.9 211 214 A E S S- 0 0 69 -24,-0.5 -67,-0.2 -26,-0.3 -2,-0.1 -0.701 75.9-146.1 -84.7 119.2 -20.6 -10.4 22.1 212 215 A P - 0 0 28 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.416 12.3-125.6 -72.8 156.7 -18.6 -11.4 19.0 213 216 A I E -l 145 0B 3 -69,-2.9 -67,-2.4 -30,-0.1 2,-0.5 -0.757 23.1-126.8 -90.9 150.5 -20.0 -11.1 15.5 214 217 A S E +l 146 0B 30 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.877 28.6 178.2 -97.5 133.6 -20.0 -14.2 13.3 215 218 A V E -l 147 0B 1 -69,-2.7 -67,-3.0 -2,-0.5 -65,-0.3 -0.904 31.1-104.4-123.7 158.6 -18.5 -14.0 9.9 216 219 A S > - 0 0 12 -2,-0.3 4,-2.2 -69,-0.2 5,-0.2 -0.428 23.7-116.5 -83.0 160.1 -18.1 -16.9 7.4 217 220 A S H > S+ 0 0 43 -69,-0.4 4,-2.7 1,-0.2 5,-0.2 0.907 118.5 55.5 -55.7 -39.3 -15.0 -18.7 6.6 218 221 A E H > S+ 0 0 130 2,-0.2 4,-1.4 1,-0.2 -1,-0.2 0.893 105.2 52.2 -64.3 -38.0 -15.3 -17.4 3.0 219 222 A Q H > S+ 0 0 2 2,-0.2 4,-1.3 1,-0.2 3,-0.4 0.960 113.4 41.9 -62.9 -49.0 -15.4 -13.8 4.3 220 223 A V H X S+ 0 0 2 -4,-2.2 4,-1.8 1,-0.2 -2,-0.2 0.882 107.6 61.4 -71.6 -31.5 -12.3 -14.1 6.4 221 224 A L H < S+ 0 0 85 -4,-2.7 -1,-0.2 -5,-0.2 4,-0.2 0.868 102.1 54.1 -57.7 -34.9 -10.5 -16.1 3.6 222 225 A K H >< S+ 0 0 88 -4,-1.4 3,-1.2 -3,-0.4 4,-0.4 0.874 102.8 55.2 -70.2 -36.4 -10.9 -13.0 1.5 223 226 A F H >< S+ 0 0 1 -4,-1.3 3,-1.4 1,-0.2 -1,-0.2 0.915 104.5 56.0 -54.8 -42.1 -9.2 -10.8 4.1 224 227 A R T 3< S+ 0 0 24 -4,-1.8 -1,-0.2 1,-0.3 -2,-0.2 0.483 94.4 67.0 -76.1 -1.7 -6.3 -13.2 3.9 225 228 A K T < S+ 0 0 139 -3,-1.2 -1,-0.3 -4,-0.2 -2,-0.2 0.563 79.8 102.4 -92.3 -10.3 -5.9 -12.6 0.1 226 229 A L < - 0 0 3 -3,-1.4 12,-2.8 -4,-0.4 2,-0.4 -0.184 69.0-128.0 -61.6 163.7 -4.9 -9.0 0.7 227 230 A N B -O 237 0C 5 -62,-2.7 -166,-0.2 10,-0.3 10,-0.2 -0.953 17.6-157.7-122.1 139.9 -1.2 -8.2 0.4 228 231 A F S S+ 0 0 34 8,-2.9 9,-0.1 -2,-0.4 -1,-0.1 0.778 81.2 75.3 -73.1 -34.2 1.2 -6.3 2.7 229 232 A N S S- 0 0 3 7,-0.6 -62,-2.2 1,-0.1 -2,-0.1 -0.311 86.2-107.8 -75.0 162.0 3.4 -5.6 -0.4 230 233 A G > - 0 0 8 -64,-0.3 3,-1.7 1,-0.2 -1,-0.1 -0.330 52.0 -66.8 -78.8 168.0 2.9 -3.0 -3.2 231 234 A E T 3 S+ 0 0 158 -64,-0.5 -1,-0.2 1,-0.2 0, 0.0 -0.301 122.0 18.3 -54.0 134.5 1.9 -3.7 -6.8 232 235 A G T 3 S+ 0 0 87 1,-0.3 -1,-0.2 -3,-0.1 3,-0.0 0.506 101.7 112.4 78.1 6.1 4.6 -5.5 -8.7 233 236 A E S < S- 0 0 96 -3,-1.7 -1,-0.3 1,-0.1 -4,-0.1 -0.642 82.1 -79.5-102.4 163.8 6.4 -6.7 -5.6 234 237 A P - 0 0 107 0, 0.0 2,-0.3 0, 0.0 -5,-0.1 -0.401 60.6 -96.0 -64.9 144.5 6.7 -10.3 -4.4 235 238 A E + 0 0 117 -7,-0.1 2,-0.5 -2,-0.1 -8,-0.0 -0.429 42.4 174.7 -74.6 126.2 3.5 -11.5 -2.6 236 239 A E - 0 0 107 -2,-0.3 -8,-2.9 -3,-0.1 -7,-0.6 -0.965 32.7-130.0-123.3 106.5 3.4 -11.3 1.2 237 240 A L B -O 227 0C 84 -2,-0.5 2,-1.5 -10,-0.2 -10,-0.3 -0.366 17.0-120.0 -61.9 138.1 -0.1 -12.2 2.3 238 241 A M + 0 0 0 -12,-2.8 2,-0.3 -15,-0.2 -12,-0.3 -0.643 65.9 128.6 -80.4 89.0 -1.7 -9.7 4.7 239 242 A V + 0 0 29 -2,-1.5 -143,-0.2 1,-0.1 -142,-0.2 -0.967 52.4 28.3-139.5 155.5 -2.2 -12.1 7.6 240 243 A D + 0 0 41 -145,-0.9 2,-0.6 -2,-0.3 -144,-0.2 0.887 63.2 155.9 58.7 46.5 -1.4 -12.0 11.3 241 244 A N + 0 0 0 -146,-1.2 2,-0.4 -3,-0.1 -1,-0.2 -0.301 36.0 113.7 -96.3 47.9 -1.5 -8.2 11.5 242 245 A W - 0 0 43 -2,-0.6 -139,-0.1 -148,-0.1 -138,-0.1 -0.947 61.9-137.1-121.9 140.7 -2.2 -8.3 15.2 243 246 A R - 0 0 4 -2,-0.4 3,-0.1 -141,-0.1 -2,-0.1 -0.777 32.7-120.6 -87.5 136.7 -0.2 -7.1 18.2 244 247 A P - 0 0 52 0, 0.0 -140,-0.1 0, 0.0 -139,-0.1 -0.245 42.9 -68.4 -74.8 169.5 -0.2 -9.6 21.1 245 248 A A - 0 0 48 -141,-0.1 -216,-0.3 -216,-0.1 -218,-0.1 -0.303 51.9-151.2 -59.0 137.7 -1.5 -8.9 24.6 246 249 A Q - 0 0 43 -218,-2.7 -216,-0.4 -220,-0.2 -1,-0.1 -0.683 34.1 -71.5-108.5 161.7 0.6 -6.4 26.6 247 250 A P - 0 0 75 0, 0.0 -221,-0.4 0, 0.0 -1,-0.1 -0.278 32.7-145.8 -59.2 134.1 1.2 -6.2 30.4 248 251 A L + 0 0 61 1,-0.2 -219,-0.0 -223,-0.1 -2,-0.0 0.829 36.0 169.0 -68.6 -32.9 -1.9 -4.8 32.3 249 252 A K - 0 0 115 1,-0.2 2,-1.6 -224,-0.1 -1,-0.2 -0.263 65.3 -5.4 53.6-135.1 0.3 -3.0 34.8 250 253 A N S S+ 0 0 159 -226,-0.3 2,-0.3 2,-0.0 -1,-0.2 -0.454 107.4 111.5 -94.0 63.8 -1.6 -0.7 37.0 251 254 A R - 0 0 26 -2,-1.6 2,-0.4 -60,-0.0 -3,-0.0 -0.968 50.3-151.3-134.5 151.8 -5.0 -1.0 35.3 252 255 A Q - 0 0 143 -2,-0.3 2,-0.5 -216,-0.0 -216,-0.1 -0.965 14.8-141.2-118.9 135.8 -8.4 -2.3 36.1 253 256 A I - 0 0 11 -2,-0.4 -216,-1.8 -62,-0.1 2,-0.4 -0.835 20.9-154.2 -92.1 129.5 -10.8 -3.6 33.4 254 257 A K E -cN 37 190B 46 -64,-2.5 -64,-2.5 -2,-0.5 2,-0.4 -0.864 1.6-144.6-108.1 145.5 -14.4 -2.6 34.2 255 258 A A E -cN 38 189B 6 -218,-2.4 -216,-2.6 -2,-0.4 -66,-0.2 -0.874 8.7-152.7-107.7 144.0 -17.5 -4.4 33.0 256 259 A S S S+ 0 0 29 -68,-2.7 2,-0.3 -2,-0.4 -67,-0.1 0.504 79.9 57.9 -87.2 -4.4 -20.7 -2.8 32.0 257 260 A F 0 0 31 -69,-0.3 -2,-0.1 1,-0.1 -218,-0.1 -0.869 360.0 360.0-133.0 154.6 -22.7 -5.9 32.9 258 261 A K 0 0 149 -2,-0.3 -220,-0.1 -220,-0.1 -1,-0.1 0.737 360.0 360.0 -88.5 360.0 -23.3 -8.0 35.9