==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE 28-JUN-07 2QG0 . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.H.PARK . 414 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 19665.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 304 73.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 8 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 80 19.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 28 6.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 64 15.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 110 26.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 1 3 0 2 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 4 2 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 17 A V 0 0 117 0, 0.0 2,-0.4 0, 0.0 156,-0.2 0.000 360.0 360.0 360.0 116.7 30.7 43.3 15.3 2 18 A E E -A 156 0A 90 154,-2.8 154,-2.3 2,-0.0 2,-0.4 -0.872 360.0-154.5-106.2 137.3 32.0 40.7 12.8 3 19 A T E -A 155 0A 95 -2,-0.4 2,-0.3 152,-0.2 152,-0.2 -0.929 14.0-177.0-113.9 133.4 30.7 40.4 9.3 4 20 A F E -A 154 0A 51 150,-3.0 150,-2.1 -2,-0.4 2,-0.4 -0.903 25.0-124.3-128.0 155.1 30.8 37.2 7.3 5 21 A A E -A 153 0A 83 -2,-0.3 148,-0.3 148,-0.2 3,-0.1 -0.832 32.5-118.7 -98.6 132.6 29.9 36.1 3.8 6 22 A F - 0 0 12 146,-1.9 87,-0.2 -2,-0.4 86,-0.1 -0.406 41.0 -94.2 -65.0 148.3 27.4 33.2 3.5 7 23 A Q >> - 0 0 73 85,-2.6 4,-2.1 1,-0.1 3,-1.0 -0.406 45.5-107.1 -59.9 144.4 28.9 30.2 1.8 8 24 A A H 3> S+ 0 0 57 1,-0.3 4,-2.4 2,-0.2 5,-0.2 0.843 117.0 51.0 -43.5 -51.8 27.9 30.6 -1.9 9 25 A E H 3> S+ 0 0 67 1,-0.2 4,-2.0 2,-0.2 -1,-0.3 0.839 109.7 50.7 -60.4 -33.9 25.3 27.8 -1.9 10 26 A I H <> S+ 0 0 0 -3,-1.0 4,-2.9 2,-0.2 -1,-0.2 0.950 110.0 49.5 -69.0 -46.1 23.6 29.2 1.2 11 27 A A H X S+ 0 0 31 -4,-2.1 4,-2.2 1,-0.2 -2,-0.2 0.907 111.1 50.9 -56.4 -43.1 23.4 32.7 -0.4 12 28 A Q H X S+ 0 0 100 -4,-2.4 4,-1.9 -5,-0.2 -1,-0.2 0.888 109.9 49.3 -61.4 -42.2 22.0 31.1 -3.5 13 29 A L H X S+ 0 0 0 -4,-2.0 4,-2.2 1,-0.2 -2,-0.2 0.933 110.5 50.9 -63.3 -46.1 19.3 29.3 -1.5 14 30 A M H X S+ 0 0 4 -4,-2.9 4,-2.1 1,-0.2 -2,-0.2 0.857 108.9 50.2 -61.6 -37.5 18.4 32.6 0.3 15 31 A S H X S+ 0 0 59 -4,-2.2 4,-2.5 2,-0.2 -1,-0.2 0.905 109.4 52.1 -67.9 -40.3 18.0 34.5 -2.9 16 32 A L H X S+ 0 0 77 -4,-1.9 4,-1.1 1,-0.2 -2,-0.2 0.909 110.6 48.0 -60.9 -42.4 15.7 31.7 -4.3 17 33 A I H < S+ 0 0 2 -4,-2.2 -1,-0.2 1,-0.2 -2,-0.2 0.897 115.8 43.3 -66.5 -41.3 13.6 31.9 -1.1 18 34 A I H < S+ 0 0 74 -4,-2.1 -2,-0.2 1,-0.2 -1,-0.2 0.799 118.7 43.4 -75.5 -29.3 13.3 35.7 -1.3 19 35 A N H < S+ 0 0 101 -4,-2.5 2,-0.2 -5,-0.2 -1,-0.2 0.528 95.3 92.8 -95.7 -5.8 12.7 35.9 -5.0 20 36 A T < - 0 0 60 -4,-1.1 -4,-0.0 -5,-0.2 -3,-0.0 -0.556 67.9-139.3 -90.2 153.5 10.2 33.0 -5.4 21 37 A F + 0 0 197 -2,-0.2 -1,-0.1 0, 0.0 -4,-0.1 -0.007 37.5 163.3 -98.9 29.7 6.4 33.3 -5.3 22 38 A Y - 0 0 28 -5,-0.2 3,-0.3 1,-0.1 -2,-0.0 -0.251 25.8-155.7 -49.7 127.3 5.8 30.2 -3.2 23 39 A S S S+ 0 0 114 1,-0.2 2,-2.3 2,-0.1 3,-0.3 0.911 78.5 66.3 -76.8 -46.9 2.2 30.5 -1.9 24 40 A N > + 0 0 49 1,-0.2 3,-1.3 2,-0.1 -1,-0.2 -0.268 57.4 147.8 -76.9 55.5 2.2 28.3 1.2 25 41 A K T > + 0 0 34 -2,-2.3 3,-2.1 -3,-0.3 -1,-0.2 0.690 48.3 87.6 -63.5 -21.1 4.6 30.6 3.1 26 42 A E T >> + 0 0 19 1,-0.3 3,-1.7 -3,-0.3 4,-0.6 0.714 67.6 81.4 -54.0 -21.4 3.0 29.8 6.5 27 43 A I H <> + 0 0 0 -3,-1.3 4,-2.2 1,-0.3 -1,-0.3 0.560 68.6 83.3 -64.5 -5.7 5.3 26.7 6.8 28 44 A F H <> S+ 0 0 0 -3,-2.1 4,-1.9 1,-0.2 -1,-0.3 0.885 90.2 51.1 -63.6 -35.7 8.0 29.1 8.0 29 45 A L H <> S+ 0 0 1 -3,-1.7 4,-2.6 2,-0.2 5,-0.3 0.900 107.9 51.2 -66.2 -42.8 6.5 28.8 11.5 30 46 A R H X S+ 0 0 50 -4,-0.6 4,-2.1 1,-0.2 -2,-0.2 0.910 110.4 50.0 -60.4 -44.7 6.4 25.0 11.3 31 47 A E H X S+ 0 0 13 -4,-2.2 4,-1.8 2,-0.2 -1,-0.2 0.861 113.6 43.5 -64.7 -39.7 10.1 24.9 10.4 32 48 A L H X S+ 0 0 4 -4,-1.9 4,-2.3 2,-0.2 -2,-0.2 0.885 114.6 49.0 -75.1 -37.8 11.2 27.2 13.2 33 49 A I H X S+ 0 0 0 -4,-2.6 4,-2.5 2,-0.2 -2,-0.2 0.869 110.2 53.8 -67.3 -33.4 9.1 25.5 15.8 34 50 A S H X S+ 0 0 15 -4,-2.1 4,-2.4 -5,-0.3 -2,-0.2 0.938 107.8 48.9 -64.2 -47.0 10.5 22.2 14.5 35 51 A N H X S+ 0 0 70 -4,-1.8 4,-2.5 1,-0.2 -2,-0.2 0.927 111.0 50.9 -58.8 -45.2 14.0 23.5 15.0 36 52 A S H X S+ 0 0 4 -4,-2.3 4,-2.1 1,-0.2 -1,-0.2 0.931 109.1 50.7 -57.7 -48.0 13.1 24.6 18.6 37 53 A S H X S+ 0 0 12 -4,-2.5 4,-2.1 1,-0.2 -1,-0.2 0.907 111.2 48.2 -56.5 -45.3 11.6 21.2 19.4 38 54 A D H X S+ 0 0 77 -4,-2.4 4,-1.8 1,-0.2 -1,-0.2 0.904 110.4 51.0 -64.2 -40.7 14.8 19.5 18.2 39 55 A A H X S+ 0 0 17 -4,-2.5 41,-1.8 1,-0.2 4,-1.8 0.840 109.9 51.5 -64.9 -32.5 17.0 21.8 20.2 40 56 A L H X S+ 0 0 0 -4,-2.1 4,-2.3 39,-0.3 -2,-0.2 0.874 105.6 53.7 -72.2 -37.5 14.8 21.0 23.2 41 57 A D H X S+ 0 0 24 -4,-2.1 4,-2.6 1,-0.2 -2,-0.2 0.905 108.0 54.1 -61.2 -40.7 15.3 17.2 22.7 42 58 A K H X S+ 0 0 68 -4,-1.8 4,-2.7 2,-0.2 5,-0.2 0.952 110.9 40.6 -59.4 -56.6 19.0 17.8 22.7 43 59 A I H X S+ 0 0 0 -4,-1.8 4,-2.4 1,-0.2 -1,-0.2 0.892 114.1 55.8 -62.4 -37.3 19.3 19.7 26.0 44 60 A R H X S+ 0 0 111 -4,-2.3 4,-0.8 1,-0.2 -1,-0.2 0.942 110.6 44.9 -59.3 -45.8 16.8 17.2 27.5 45 61 A Y H >X S+ 0 0 57 -4,-2.6 3,-0.9 1,-0.2 4,-0.6 0.922 112.0 49.5 -65.1 -46.9 19.0 14.3 26.5 46 62 A E H >X S+ 0 0 50 -4,-2.7 4,-1.9 1,-0.3 3,-1.2 0.886 106.2 58.3 -60.9 -36.4 22.3 15.8 27.7 47 63 A S H 3< S+ 0 0 15 -4,-2.4 -1,-0.3 1,-0.3 -2,-0.2 0.754 90.4 73.3 -64.4 -23.9 20.6 16.6 31.0 48 64 A L H << S+ 0 0 100 -3,-0.9 -1,-0.3 -4,-0.8 -2,-0.2 0.849 114.6 21.5 -59.7 -34.5 19.9 12.9 31.4 49 65 A T H << S+ 0 0 119 -3,-1.2 -1,-0.2 -4,-0.6 -2,-0.2 0.589 133.7 41.8-108.0 -16.1 23.5 12.3 32.2 50 66 A D >< + 0 0 61 -4,-1.9 3,-2.5 -5,-0.2 -1,-0.2 -0.686 61.3 179.3-133.7 80.1 24.5 15.8 33.2 51 67 A P G > S+ 0 0 97 0, 0.0 3,-1.7 0, 0.0 -1,-0.1 0.752 77.9 70.4 -50.2 -29.1 21.8 17.3 35.5 52 68 A S G > S+ 0 0 59 1,-0.3 3,-2.3 2,-0.2 4,-0.2 0.705 76.5 81.9 -64.8 -19.6 23.8 20.5 35.9 53 69 A K G < S+ 0 0 38 -3,-2.5 3,-0.4 1,-0.3 -1,-0.3 0.684 89.7 54.0 -59.0 -17.4 23.0 21.3 32.2 54 70 A L G X S+ 0 0 31 -3,-1.7 3,-2.3 -4,-0.2 -1,-0.3 0.345 72.1 99.3-100.2 5.2 19.7 22.6 33.5 55 71 A D T < S+ 0 0 138 -3,-2.3 -1,-0.2 1,-0.3 3,-0.1 0.718 81.8 61.0 -62.5 -15.8 21.1 25.1 36.0 56 72 A S T 3 S- 0 0 33 -3,-0.4 -1,-0.3 1,-0.3 -2,-0.1 0.136 134.5 -38.3 -95.0 17.4 20.5 27.6 33.2 57 73 A G < - 0 0 30 -3,-2.3 -1,-0.3 108,-0.1 -2,-0.1 0.101 44.7-154.3 126.6 120.8 16.7 26.8 33.3 58 74 A K + 0 0 132 -3,-0.1 2,-0.2 -2,-0.1 -3,-0.1 0.717 67.7 100.1 -91.1 -24.8 14.8 23.5 33.7 59 75 A E - 0 0 123 -5,-0.1 2,-0.6 1,-0.1 0, 0.0 -0.451 56.9-160.4 -67.4 129.7 11.7 24.6 31.8 60 76 A L + 0 0 28 -2,-0.2 2,-0.3 17,-0.1 19,-0.1 -0.927 37.3 116.4-114.9 104.9 11.6 23.2 28.3 61 77 A H - 0 0 52 -2,-0.6 17,-1.2 139,-0.2 2,-0.4 -0.928 53.4-115.9-156.5-178.6 9.2 25.1 26.1 62 78 A I E -Bc 77 202A 0 139,-2.8 141,-2.6 -2,-0.3 2,-0.4 -0.997 21.0-163.5-133.1 131.3 8.5 27.3 23.1 63 79 A N E -Bc 76 203A 23 13,-2.9 13,-3.1 -2,-0.4 2,-0.5 -0.935 5.6-157.8-117.7 135.9 7.1 30.9 23.1 64 80 A L E -Bc 75 204A 1 139,-2.9 141,-2.8 -2,-0.4 11,-0.2 -0.962 13.7-172.0-113.0 121.0 5.6 32.8 20.1 65 81 A I E -B 74 0A 53 9,-2.9 9,-2.4 -2,-0.5 2,-0.3 -0.895 3.6-170.9-122.4 106.1 5.7 36.5 20.5 66 82 A P E -B 73 0A 9 0, 0.0 2,-0.3 0, 0.0 7,-0.2 -0.664 4.1-178.4 -91.9 147.7 4.0 38.8 18.1 67 83 A N E >> -B 72 0A 47 5,-2.0 5,-2.0 -2,-0.3 4,-0.8 -0.809 9.9-176.4-146.3 100.7 4.5 42.6 18.2 68 84 A K T 45S+ 0 0 86 -2,-0.3 -1,-0.1 3,-0.2 5,-0.0 0.777 84.8 60.7 -69.2 -25.6 2.5 44.6 15.7 69 85 A Q T 45S+ 0 0 147 1,-0.2 -1,-0.2 3,-0.1 -2,-0.0 0.919 117.3 28.7 -68.3 -42.3 4.2 47.8 16.8 70 86 A D T 45S- 0 0 105 2,-0.1 -1,-0.2 -3,-0.1 -2,-0.2 0.441 105.7-128.9 -95.5 -0.8 7.7 46.6 15.9 71 87 A R T <5 + 0 0 86 -4,-0.8 103,-1.5 1,-0.2 2,-0.3 0.921 63.8 130.8 52.1 49.4 6.2 44.4 13.1 72 88 A T E < -BD 67 173A 14 -5,-2.0 -5,-2.0 101,-0.2 2,-0.4 -0.947 47.0-158.7-131.2 152.0 8.1 41.3 14.4 73 89 A L E -BD 66 172A 1 99,-1.5 99,-2.7 -2,-0.3 2,-0.4 -1.000 20.0-160.9-126.6 123.4 7.2 37.7 15.3 74 90 A T E -BD 65 171A 14 -9,-2.4 -9,-2.9 -2,-0.4 2,-0.6 -0.915 10.3-159.9-114.5 133.8 9.6 36.1 17.6 75 91 A I E -BD 64 170A 0 95,-2.6 95,-3.0 -2,-0.4 2,-0.4 -0.948 18.9-175.8-109.9 119.1 10.1 32.3 18.2 76 92 A V E +BD 63 169A 19 -13,-3.1 -13,-2.9 -2,-0.6 2,-0.3 -0.922 8.3 170.1-120.2 141.6 11.8 31.5 21.5 77 93 A D E -BD 62 168A 6 91,-2.0 91,-1.2 -2,-0.4 -15,-0.2 -0.934 35.5-138.0-141.4 162.9 12.9 28.2 23.0 78 94 A T + 0 0 27 -17,-1.2 89,-0.2 -2,-0.3 -16,-0.1 -0.262 61.6 132.5-113.5 40.2 14.9 27.1 25.9 79 95 A G S S- 0 0 0 89,-0.2 -39,-0.3 -18,-0.1 -40,-0.1 0.064 79.0 -67.5 -76.7-166.3 16.7 24.4 23.9 80 96 A I S S- 0 0 16 -41,-1.8 59,-0.5 1,-0.1 87,-0.2 0.723 70.5-156.0 -59.6 -25.0 20.4 23.6 23.7 81 97 A G - 0 0 4 85,-0.1 2,-0.4 57,-0.1 87,-0.2 -0.081 17.0 -81.0 73.0-179.5 21.2 27.0 22.0 82 98 A M - 0 0 26 85,-0.5 56,-0.4 62,-0.1 62,-0.2 -0.981 26.7-138.4-129.4 138.9 24.2 27.7 19.8 83 99 A T > - 0 0 23 -2,-0.4 4,-2.4 54,-0.1 5,-0.2 -0.290 42.8 -96.7 -79.3 174.4 27.8 28.6 20.7 84 100 A K H > S+ 0 0 56 1,-0.2 4,-1.9 2,-0.2 5,-0.2 0.911 129.6 49.3 -60.5 -40.5 29.5 31.4 18.6 85 101 A A H > S+ 0 0 65 1,-0.2 4,-2.2 2,-0.2 5,-0.2 0.900 108.4 53.2 -64.0 -41.4 31.0 28.6 16.4 86 102 A D H >>S+ 0 0 50 1,-0.2 4,-3.5 2,-0.2 5,-0.6 0.927 107.5 52.0 -58.9 -47.3 27.7 26.9 16.0 87 103 A L H X5S+ 0 0 0 -4,-2.4 4,-1.6 1,-0.2 5,-0.3 0.919 112.5 43.3 -55.4 -50.8 26.1 30.2 14.8 88 104 A I H X5S+ 0 0 46 -4,-1.9 4,-0.6 3,-0.2 -1,-0.2 0.844 123.7 37.7 -66.3 -35.0 28.7 30.8 12.1 89 105 A N H X5S+ 0 0 29 -4,-2.2 4,-1.4 -5,-0.2 -2,-0.2 0.942 120.5 40.2 -82.7 -53.5 28.7 27.2 11.0 90 106 A N H <5S+ 0 0 72 -4,-3.5 -3,-0.2 -5,-0.2 -2,-0.2 0.832 129.2 30.5 -67.1 -34.2 25.1 26.1 11.3 91 107 A L H < + 0 0 25 -2,-0.3 3,-2.6 1,-0.2 5,-0.2 0.918 61.3 152.9 -55.2 -45.6 26.1 24.2 4.2 95 111 A A T 3 S- 0 0 10 1,-0.3 -1,-0.2 158,-0.1 -5,-0.1 -0.242 75.8 -17.7 52.1-126.1 27.7 22.2 7.1 96 112 A K T 3 S+ 0 0 87 -3,-0.1 -1,-0.3 23,-0.1 -2,-0.1 0.410 112.9 112.2 -90.9 4.0 25.7 19.0 7.7 97 113 A S S < S- 0 0 18 -3,-2.6 3,-0.3 -4,-0.2 22,-0.2 -0.194 73.8-125.9 -73.9 166.8 22.7 20.4 5.8 98 114 A G > + 0 0 8 20,-3.7 4,-3.1 1,-0.2 5,-0.2 -0.221 59.1 138.3-105.7 40.9 21.3 19.1 2.5 99 115 A T H > S+ 0 0 0 2,-0.2 4,-2.6 1,-0.2 5,-0.2 0.920 72.9 46.2 -49.7 -53.9 21.5 22.5 0.8 100 116 A K H > S+ 0 0 127 -3,-0.3 4,-2.5 1,-0.2 5,-0.2 0.951 114.1 48.0 -56.6 -52.2 22.8 21.1 -2.4 101 117 A A H > S+ 0 0 15 1,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.903 112.3 50.3 -55.7 -44.8 20.3 18.3 -2.5 102 118 A F H X S+ 0 0 0 -4,-3.1 4,-2.1 2,-0.2 -1,-0.2 0.908 110.1 48.3 -62.4 -44.6 17.5 20.7 -1.8 103 119 A M H X S+ 0 0 23 -4,-2.6 4,-1.3 -5,-0.2 -1,-0.2 0.900 113.5 47.7 -64.6 -38.7 18.4 23.1 -4.5 104 120 A E H X S+ 0 0 106 -4,-2.5 4,-1.1 -5,-0.2 3,-0.3 0.918 109.9 53.4 -67.7 -40.2 18.7 20.3 -7.0 105 121 A A H <>S+ 0 0 3 -4,-2.6 5,-3.0 1,-0.2 3,-0.5 0.878 103.6 56.1 -61.0 -39.5 15.4 18.9 -5.9 106 122 A L H ><5S+ 0 0 44 -4,-2.1 3,-1.2 1,-0.3 -1,-0.2 0.867 105.8 51.4 -61.6 -35.1 13.7 22.3 -6.4 107 123 A Q H 3<5S+ 0 0 171 -4,-1.3 -1,-0.3 -3,-0.3 -2,-0.2 0.752 107.5 54.5 -72.0 -23.7 14.9 22.2 -10.0 108 124 A A T 3<5S- 0 0 58 -4,-1.1 -1,-0.3 -3,-0.5 -2,-0.2 0.236 132.4 -89.3 -93.6 11.6 13.4 18.7 -10.3 109 125 A G T < 5S+ 0 0 66 -3,-1.2 -3,-0.2 1,-0.2 -2,-0.1 0.561 74.0 154.0 94.7 8.8 10.0 19.9 -9.2 110 126 A A < - 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