==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=11-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 03-OCT-03 1R3S . COMPND 2 MOLECULE: UROPORPHYRINOGEN DECARBOXYLASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR J.D.PHILLIPS,F.G.WHITBY,J.P.KUSHNER,C.P.HILL . 356 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14813.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 250 70.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 31 8.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 16 4.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 46 12.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 136 38.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 2.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 2 0 2 2 1 1 0 0 0 2 1 0 1 0 1 0 0 0 0 1 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 2 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 11 A F 0 0 110 0, 0.0 132,-0.1 0, 0.0 3,-0.1 0.000 360.0 360.0 360.0 157.7 21.1 48.6 65.1 2 12 A P - 0 0 34 0, 0.0 2,-0.2 0, 0.0 135,-0.2 -0.237 360.0 -99.3 -57.2 145.3 22.1 47.9 61.6 3 13 A E - 0 0 174 133,-0.1 2,-0.2 1,-0.1 0, 0.0 -0.478 40.9-107.2 -69.2 137.3 25.8 48.5 60.8 4 14 A L - 0 0 38 -2,-0.2 3,-0.2 1,-0.2 134,-0.2 -0.470 33.9-176.9 -66.4 129.4 26.5 51.8 59.1 5 15 A K S S+ 0 0 171 132,-3.2 2,-0.8 1,-0.3 133,-0.2 0.898 74.3 37.2 -91.1 -56.2 27.4 51.5 55.5 6 16 A N + 0 0 37 132,-1.0 -1,-0.3 131,-0.8 3,-0.2 -0.898 61.7 160.7-106.0 105.8 28.2 55.0 54.3 7 17 A D >> + 0 0 67 -2,-0.8 4,-2.3 -3,-0.2 3,-0.8 0.174 34.4 117.0-109.0 17.8 30.0 56.8 57.2 8 18 A T H 3> S+ 0 0 12 1,-0.3 4,-2.6 2,-0.2 5,-0.2 0.843 73.8 55.1 -56.1 -43.7 31.5 59.6 55.2 9 19 A F H 3> S+ 0 0 1 60,-0.4 4,-2.0 2,-0.2 -1,-0.3 0.877 110.3 45.4 -56.0 -42.6 29.6 62.3 57.1 10 20 A L H <> S+ 0 0 28 -3,-0.8 4,-2.1 2,-0.2 -2,-0.2 0.926 111.7 51.7 -70.8 -42.9 30.9 61.0 60.5 11 21 A R H X>S+ 0 0 65 -4,-2.3 5,-2.4 1,-0.2 4,-0.6 0.945 112.3 46.5 -58.2 -46.7 34.5 60.7 59.2 12 22 A A H ><5S+ 0 0 3 -4,-2.6 3,-1.1 3,-0.2 -1,-0.2 0.893 109.3 55.4 -60.9 -41.4 34.3 64.3 58.0 13 23 A A H 3<5S+ 0 0 2 -4,-2.0 277,-0.4 1,-0.3 -1,-0.2 0.867 108.1 47.8 -60.0 -38.2 32.7 65.5 61.3 14 24 A W H 3<5S- 0 0 116 -4,-2.1 -1,-0.3 -3,-0.1 -2,-0.2 0.551 123.7-105.7 -80.9 -9.7 35.6 64.1 63.3 15 25 A G T <<5 + 0 0 32 -3,-1.1 -3,-0.2 -4,-0.6 2,-0.2 0.563 69.2 145.0 96.7 13.5 38.1 65.7 60.9 16 26 A E < - 0 0 97 -5,-2.4 -1,-0.3 -6,-0.2 306,-0.3 -0.513 56.0-101.6 -80.0 151.2 39.3 62.7 58.9 17 27 A E - 0 0 104 -2,-0.2 2,-0.3 304,-0.1 -1,-0.1 -0.459 43.3-169.8 -67.4 140.9 40.2 62.8 55.3 18 28 A T - 0 0 9 302,-0.2 3,-0.0 -2,-0.1 -9,-0.0 -0.921 34.2-118.1-129.2 164.6 37.5 61.4 53.0 19 29 A D S S+ 0 0 118 -2,-0.3 2,-0.3 1,-0.1 336,-0.2 0.617 98.0 4.2 -76.3 -19.4 37.2 60.5 49.3 20 30 A Y S S- 0 0 30 300,-0.1 328,-0.1 334,-0.1 -1,-0.1 -0.960 87.3 -90.3-155.3 170.1 34.6 63.1 48.7 21 31 A T - 0 0 0 326,-0.4 330,-0.1 -2,-0.3 303,-0.1 -0.801 40.7-134.2 -90.8 123.1 32.7 65.8 50.6 22 32 A P - 0 0 0 0, 0.0 303,-2.2 0, 0.0 2,-0.3 -0.465 24.9-164.5 -75.7 152.0 29.6 64.6 52.3 23 33 A V B +a 325 0A 0 44,-0.2 46,-2.9 301,-0.2 47,-0.4 -0.989 19.4 160.8-139.9 142.2 26.5 66.7 51.9 24 34 A W - 0 0 0 301,-1.7 2,-0.4 -2,-0.3 303,-0.3 -0.943 28.0-127.9-146.9 171.8 23.1 67.1 53.5 25 35 A C > - 0 0 0 -2,-0.3 3,-2.0 45,-0.2 4,-0.2 -0.975 18.0-120.3-127.9 130.4 20.5 69.9 53.6 26 36 A M T 3 S+ 0 0 7 -2,-0.4 305,-2.1 1,-0.3 303,-0.1 -0.400 106.0 16.0 -62.9 139.7 18.8 71.7 56.4 27 37 A R T 3 S+ 0 0 163 303,-0.3 -1,-0.3 2,-0.1 303,-0.0 0.677 77.4 149.3 57.4 31.4 15.0 71.1 56.0 28 38 A Q S < S+ 0 0 2 -3,-2.0 2,-0.9 1,-0.2 -2,-0.1 0.819 71.9 58.5 -58.7 -32.2 15.7 68.3 53.5 29 39 A A S S+ 0 0 16 -4,-0.2 2,-0.3 32,-0.1 -1,-0.2 -0.904 94.6 116.8 -90.5 106.5 12.4 66.9 54.9 30 40 A G S > S- 0 0 8 -2,-0.9 3,-2.2 28,-0.1 6,-0.3 -0.978 80.8 -80.6-167.1 172.5 10.3 70.0 54.0 31 41 A R T 3 S+ 0 0 140 1,-0.3 6,-0.3 -2,-0.3 5,-0.1 0.682 108.6 78.5 -60.8 -22.9 7.4 71.5 52.1 32 42 A Y T 3 S+ 0 0 3 4,-0.1 -1,-0.3 299,-0.1 3,-0.1 0.719 84.8 78.0 -60.5 -21.7 9.5 71.9 48.9 33 43 A L S X> S- 0 0 0 -3,-2.2 4,-1.8 1,-0.1 3,-0.7 -0.818 74.4-151.8 -87.7 121.7 8.7 68.1 48.5 34 44 A P H 3> S+ 0 0 59 0, 0.0 4,-2.1 0, 0.0 -1,-0.1 0.894 99.4 55.7 -58.0 -37.1 5.2 67.4 47.2 35 45 A E H 3> S+ 0 0 50 1,-0.2 4,-2.1 2,-0.2 5,-0.2 0.788 102.8 55.6 -66.4 -29.5 5.3 64.0 49.1 36 46 A F H <> S+ 0 0 15 -3,-0.7 4,-2.5 -6,-0.3 -1,-0.2 0.939 108.6 47.8 -64.8 -46.8 6.1 65.9 52.4 37 47 A R H X S+ 0 0 124 -4,-1.8 4,-2.0 -6,-0.3 -2,-0.2 0.921 110.8 51.5 -61.4 -43.4 3.0 68.0 51.9 38 48 A E H X S+ 0 0 160 -4,-2.1 4,-0.6 1,-0.2 -1,-0.2 0.928 112.6 44.5 -57.4 -49.3 0.9 64.9 51.2 39 49 A T H >< S+ 0 0 42 -4,-2.1 3,-0.6 1,-0.2 4,-0.3 0.879 115.8 48.0 -65.1 -38.9 2.1 63.1 54.3 40 50 A R H >< S+ 0 0 46 -4,-2.5 3,-1.6 1,-0.2 -1,-0.2 0.801 91.6 78.2 -70.2 -28.9 1.6 66.2 56.5 41 51 A A H 3< S+ 0 0 87 -4,-2.0 -1,-0.2 1,-0.3 -2,-0.2 0.806 85.7 64.7 -56.7 -29.9 -1.9 67.0 55.2 42 52 A A T << S+ 0 0 83 -4,-0.6 -1,-0.3 -3,-0.6 2,-0.2 0.797 111.3 16.4 -58.7 -39.6 -3.2 64.2 57.5 43 53 A Q S < S- 0 0 63 -3,-1.6 2,-0.2 -4,-0.3 3,-0.0 -0.805 81.2 -92.6-129.6 172.6 -2.3 66.0 60.8 44 54 A D > - 0 0 108 -2,-0.2 4,-2.3 1,-0.1 3,-0.5 -0.517 52.6-103.2 -76.1 158.3 -1.3 69.2 62.5 45 55 A F H > S+ 0 0 36 1,-0.3 4,-2.1 2,-0.2 5,-0.1 0.873 119.4 46.0 -58.4 -49.1 2.5 69.7 62.8 46 56 A F H > S+ 0 0 11 1,-0.2 4,-0.6 2,-0.2 -1,-0.3 0.774 112.1 53.1 -70.1 -25.3 3.0 68.8 66.5 47 57 A S H >4 S+ 0 0 43 -3,-0.5 3,-0.7 2,-0.2 -2,-0.2 0.878 107.1 51.8 -70.9 -40.7 0.7 65.7 66.0 48 58 A T H >< S+ 0 0 0 -4,-2.3 3,-2.0 1,-0.2 7,-0.3 0.935 105.0 57.1 -58.0 -44.9 2.9 64.6 63.1 49 59 A C H 3< S+ 0 0 1 -4,-2.1 -1,-0.2 1,-0.3 -2,-0.2 0.782 103.1 55.2 -57.7 -27.2 5.9 64.9 65.4 50 60 A R T << S+ 0 0 121 -3,-0.7 -1,-0.3 -4,-0.6 -2,-0.2 0.321 89.8 83.6 -91.2 4.9 4.3 62.5 67.8 51 61 A S <> - 0 0 35 -3,-2.0 4,-2.4 -4,-0.2 5,-0.2 -0.926 63.0-160.6-108.0 107.1 3.8 59.7 65.2 52 62 A P H > S+ 0 0 35 0, 0.0 4,-2.4 0, 0.0 5,-0.2 0.915 92.1 50.2 -54.4 -42.3 7.0 57.6 64.9 53 63 A E H > S+ 0 0 101 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.895 110.5 48.9 -65.1 -38.8 5.9 56.2 61.5 54 64 A A H > S+ 0 0 19 2,-0.2 4,-2.3 1,-0.2 5,-0.2 0.936 112.6 48.0 -66.1 -41.6 5.1 59.7 60.1 55 65 A C H X S+ 0 0 1 -4,-2.4 4,-2.2 -7,-0.3 19,-0.5 0.905 112.0 49.6 -64.0 -42.0 8.4 61.1 61.3 56 66 A C H X S+ 0 0 2 -4,-2.4 4,-2.2 -5,-0.2 -1,-0.2 0.943 111.0 49.6 -61.4 -46.0 10.3 58.1 59.8 57 67 A E H X S+ 0 0 66 -4,-2.3 4,-2.0 1,-0.2 -2,-0.2 0.942 112.1 47.1 -60.4 -46.0 8.5 58.5 56.5 58 68 A L H < S+ 0 0 1 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.895 111.3 52.4 -66.7 -33.8 9.3 62.2 56.3 59 69 A T H < S+ 0 0 2 -4,-2.2 4,-0.5 -5,-0.2 -1,-0.2 0.890 112.8 44.6 -65.8 -41.1 12.9 61.6 57.2 60 70 A L H >X S+ 0 0 26 -4,-2.2 4,-0.8 1,-0.2 3,-0.7 0.812 92.7 81.3 -76.0 -29.3 13.3 59.0 54.4 61 71 A Q H >X S+ 0 0 3 -4,-2.0 3,-1.4 1,-0.3 4,-0.9 0.868 95.6 42.0 -50.5 -51.5 11.5 60.9 51.6 62 72 A P H >> S+ 0 0 0 0, 0.0 4,-2.5 0, 0.0 3,-0.5 0.862 108.1 61.1 -60.5 -34.4 14.5 63.1 50.6 63 73 A L H <4 S+ 0 0 10 -3,-0.7 -2,-0.2 -4,-0.5 -3,-0.1 0.573 101.2 54.2 -63.5 -31.8 16.8 60.2 51.0 64 74 A R H << S+ 0 0 144 -3,-1.4 -1,-0.2 -4,-0.8 -3,-0.1 0.701 115.6 41.0 -75.8 -24.6 14.6 58.4 48.0 65 75 A R H << S+ 0 0 94 -4,-0.9 -2,-0.2 -3,-0.5 -1,-0.1 0.804 122.3 25.2 -90.5 -38.5 15.2 61.4 45.8 66 76 A F S < S- 0 0 11 -4,-2.5 2,-2.1 278,-0.0 -1,-0.2 -0.984 73.1-117.6-135.8 146.5 18.8 62.3 46.4 67 77 A P + 0 0 70 0, 0.0 -44,-0.2 0, 0.0 -4,-0.1 -0.299 48.7 173.2 -80.4 58.6 22.0 60.5 47.6 68 78 A L - 0 0 4 -2,-2.1 -44,-0.2 -6,-0.2 3,-0.0 -0.357 34.3-135.7 -65.4 148.3 22.3 62.7 50.7 69 79 A D S S+ 0 0 3 -46,-2.9 -60,-0.4 1,-0.1 2,-0.3 0.404 82.5 27.1 -91.8 0.5 25.1 61.6 53.1 70 80 A A - 0 0 0 -47,-0.4 2,-0.3 69,-0.2 -45,-0.2 -0.980 64.7-142.9-154.6 152.9 23.0 62.0 56.3 71 81 A A E -b 141 0A 0 69,-2.7 71,-3.0 -2,-0.3 2,-0.4 -0.860 14.8-151.8-107.3 150.2 19.4 61.9 57.4 72 82 A I E -b 142 0A 18 -2,-0.3 71,-0.2 -13,-0.2 -43,-0.1 -0.996 27.5-108.6-122.2 133.4 18.0 64.2 60.0 73 83 A I - 0 0 3 69,-2.5 2,-0.6 -2,-0.4 -17,-0.1 -0.323 31.1-116.6 -61.2 137.0 15.1 63.1 62.2 74 84 A F + 0 0 16 -19,-0.5 2,-0.2 53,-0.1 -1,-0.1 -0.691 68.7 106.8 -73.8 120.0 11.8 64.9 61.4 75 85 A S - 0 0 14 -2,-0.6 2,-0.3 -25,-0.0 3,-0.1 -0.869 61.2-100.7-165.3-162.7 10.8 66.8 64.6 76 86 A G > - 0 0 8 -2,-0.2 3,-0.7 1,-0.1 4,-0.2 -0.961 12.1-134.5-134.7 151.4 10.7 70.4 65.8 77 87 A I T > S+ 0 0 30 -2,-0.3 3,-1.3 1,-0.2 69,-0.4 0.803 104.7 66.9 -70.8 -24.6 12.9 72.5 68.1 78 88 A L T 3> S+ 0 0 9 1,-0.3 4,-2.0 2,-0.2 -1,-0.2 0.568 73.0 87.0 -77.6 -1.4 9.7 73.7 69.8 79 89 A V H <> S+ 0 0 0 -3,-0.7 4,-2.2 2,-0.2 -1,-0.3 0.799 85.4 58.9 -62.4 -26.0 9.0 70.2 71.3 80 90 A V H <> S+ 0 0 1 -3,-1.3 4,-1.6 2,-0.2 -1,-0.2 0.981 106.4 42.6 -72.2 -56.2 11.3 71.2 74.2 81 91 A P H 4>S+ 0 0 0 0, 0.0 5,-2.1 0, 0.0 4,-0.3 0.879 115.5 52.7 -52.7 -37.1 9.3 74.3 75.3 82 92 A Q H ><5S+ 0 0 28 -4,-2.0 3,-1.5 1,-0.2 -2,-0.2 0.928 108.2 49.0 -63.7 -45.0 6.1 72.3 74.8 83 93 A A H 3<5S+ 0 0 5 -4,-2.2 -1,-0.2 1,-0.3 -3,-0.2 0.729 103.8 61.6 -66.0 -23.8 7.5 69.5 77.0 84 94 A L T 3<5S- 0 0 0 -4,-1.6 28,-2.7 -5,-0.1 -1,-0.3 0.524 131.0 -93.0 -78.8 -6.9 8.4 72.1 79.7 85 95 A G T < 5S+ 0 0 29 -3,-1.5 2,-0.3 1,-0.3 -3,-0.2 0.475 82.0 131.5 109.0 10.2 4.6 72.9 79.8 86 96 A M < - 0 0 4 -5,-2.1 2,-0.5 1,-0.0 -1,-0.3 -0.665 54.5-125.7 -89.7 143.1 4.0 75.7 77.4 87 97 A E - 0 0 137 -2,-0.3 13,-0.4 13,-0.2 2,-0.3 -0.832 32.1-177.2 -87.8 126.9 1.2 75.5 74.9 88 98 A V - 0 0 14 -2,-0.5 2,-0.3 10,-0.2 10,-0.2 -0.907 8.2-170.0-124.7 146.9 2.3 75.9 71.2 89 99 A T E -H 97 0B 61 8,-2.4 8,-2.5 -2,-0.3 2,-0.7 -0.931 25.1-132.4-128.9 154.3 0.3 76.0 68.0 90 100 A M E -H 96 0B 69 -2,-0.3 -45,-0.1 6,-0.2 3,-0.1 -0.947 38.4-140.0-104.0 107.0 1.3 76.0 64.3 91 101 A V E >> -H 95 0B 47 4,-2.2 3,-2.1 -2,-0.7 4,-1.4 -0.469 26.8 -90.2 -76.5 134.5 -0.9 78.8 63.0 92 102 A P T 34 S- 0 0 114 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 -0.261 106.6 -27.0 -37.0 97.5 -2.6 78.7 59.5 93 103 A G T 34 S+ 0 0 83 -2,-0.3 -2,-0.0 1,-0.1 -3,-0.0 0.641 128.9 87.4 56.6 20.9 0.1 80.2 57.4 94 104 A K T <4 S- 0 0 176 -3,-2.1 -1,-0.1 1,-0.2 -4,-0.0 0.368 83.6-134.5-125.0 2.1 1.6 82.2 60.3 95 105 A G E < -H 91 0B 24 -4,-1.4 -4,-2.2 64,-0.1 -1,-0.2 -0.143 52.3 -6.5 79.2-171.6 4.0 79.7 61.8 96 106 A P E +H 90 0B 39 0, 0.0 64,-0.4 0, 0.0 2,-0.3 -0.237 62.8 177.9 -67.4 140.7 4.6 78.7 65.5 97 107 A S E -H 89 0B 39 -8,-2.5 -8,-2.4 62,-0.1 62,-0.2 -0.999 27.0-158.7-140.3 144.8 2.9 80.6 68.3 98 108 A F - 0 0 5 60,-2.1 -10,-0.2 -2,-0.3 -12,-0.0 -0.970 12.0-163.8-111.3 107.4 2.7 80.5 72.1 99 109 A P S S+ 0 0 72 0, 0.0 -1,-0.1 0, 0.0 -11,-0.1 0.746 87.4 43.6 -65.3 -19.1 -0.5 82.4 73.0 100 110 A E S S- 0 0 113 -13,-0.4 -13,-0.2 -3,-0.1 58,-0.1 -0.705 84.0-176.8-123.5 74.2 0.7 82.7 76.6 101 111 A P - 0 0 25 0, 0.0 2,-0.5 0, 0.0 55,-0.2 -0.216 36.8 -96.4 -66.0 163.4 4.4 83.7 76.4 102 112 A L + 0 0 0 53,-2.7 3,-0.1 1,-0.2 56,-0.0 -0.709 55.0 155.3 -75.7 123.4 6.6 84.0 79.4 103 113 A R + 0 0 90 -2,-0.5 2,-0.3 1,-0.3 -1,-0.2 0.632 55.3 35.4-127.9 -23.2 6.7 87.7 80.3 104 114 A E S > S- 0 0 97 1,-0.1 3,-1.5 73,-0.0 4,-0.4 -0.873 83.5-106.3-129.2 167.6 7.5 88.1 83.9 105 115 A E G > S+ 0 0 104 -2,-0.3 3,-1.7 1,-0.3 4,-0.3 0.856 115.7 62.0 -57.5 -35.9 9.7 86.2 86.3 106 116 A Q G > S+ 0 0 122 1,-0.3 3,-1.6 2,-0.2 -1,-0.3 0.748 88.1 73.8 -64.2 -24.1 6.8 84.5 88.0 107 117 A D G X S+ 0 0 30 -3,-1.5 3,-1.6 1,-0.3 -1,-0.3 0.762 79.5 72.9 -64.5 -23.2 5.9 82.9 84.7 108 118 A L G X S+ 0 0 10 -3,-1.7 3,-1.8 -4,-0.4 -1,-0.3 0.779 81.4 74.2 -58.9 -26.6 8.8 80.5 85.2 109 119 A E G < S+ 0 0 153 -3,-1.6 -1,-0.3 -4,-0.3 -2,-0.2 0.728 86.2 62.1 -60.1 -24.4 6.8 78.8 88.0 110 120 A R G < S+ 0 0 103 -3,-1.6 -1,-0.3 -4,-0.2 2,-0.2 0.477 84.8 99.7 -85.5 3.5 4.5 77.1 85.3 111 121 A L S < S- 0 0 20 -3,-1.8 -26,-0.2 -4,-0.1 -27,-0.1 -0.586 76.2-112.3 -86.5 147.7 7.4 75.1 83.8 112 122 A R - 0 0 97 -28,-2.7 -1,-0.1 -2,-0.2 5,-0.1 -0.315 42.5 -88.8 -63.2 156.9 8.1 71.5 84.5 113 123 A D > - 0 0 93 1,-0.1 3,-2.1 2,-0.0 4,-0.4 -0.559 40.2-128.1 -60.8 129.5 11.2 70.5 86.4 114 124 A P G > S+ 0 0 17 0, 0.0 3,-1.2 0, 0.0 4,-0.5 0.790 103.8 69.7 -59.8 -25.3 13.8 70.1 83.5 115 125 A E G 3 S+ 0 0 154 1,-0.2 4,-0.2 2,-0.1 3,-0.1 0.631 98.1 50.9 -66.9 -14.5 14.6 66.6 84.8 116 126 A V G <> S+ 0 0 55 -3,-2.1 4,-1.3 1,-0.1 3,-0.3 0.513 85.7 87.8 -96.0 -9.4 11.2 65.3 83.6 117 127 A V H <> S+ 0 0 0 -3,-1.2 4,-0.9 -4,-0.4 3,-0.2 0.886 80.2 58.4 -58.4 -41.8 11.3 66.7 80.1 118 128 A A H >4 S+ 0 0 19 -4,-0.5 3,-1.1 1,-0.2 -1,-0.2 0.917 103.9 52.8 -58.2 -39.6 13.0 63.7 78.5 119 129 A S H >4 S+ 0 0 88 -3,-0.3 3,-1.2 1,-0.3 -1,-0.2 0.874 106.4 53.7 -63.3 -35.3 10.2 61.4 79.7 120 130 A E H 3< S+ 0 0 77 -4,-1.3 3,-0.3 1,-0.2 -1,-0.3 0.637 106.7 53.9 -71.1 -17.3 7.7 63.8 78.0 121 131 A L T XX + 0 0 0 -3,-1.1 3,-1.5 -4,-0.9 4,-1.4 0.091 66.9 120.8-107.5 21.7 9.7 63.5 74.7 122 132 A G H <> + 0 0 25 -3,-1.2 4,-2.6 1,-0.3 -1,-0.2 0.832 67.8 65.6 -51.6 -35.3 9.6 59.7 74.5 123 133 A Y H 3> S+ 0 0 16 -3,-0.3 4,-1.8 1,-0.2 -1,-0.3 0.807 98.4 52.0 -58.9 -32.7 7.9 60.0 71.2 124 134 A V H <> S+ 0 0 2 -3,-1.5 4,-2.3 2,-0.2 -1,-0.2 0.928 109.2 49.8 -69.0 -43.9 11.0 61.6 69.7 125 135 A F H X S+ 0 0 40 -4,-1.4 4,-2.6 1,-0.2 5,-0.2 0.908 109.5 52.3 -60.8 -42.1 13.1 58.8 70.9 126 136 A Q H X S+ 0 0 120 -4,-2.6 4,-2.3 1,-0.2 -1,-0.2 0.903 109.5 48.8 -59.2 -42.5 10.6 56.3 69.4 127 137 A A H X S+ 0 0 1 -4,-1.8 4,-2.6 2,-0.2 -1,-0.2 0.888 111.6 50.5 -61.8 -41.1 10.8 58.1 66.0 128 138 A I H X S+ 0 0 0 -4,-2.3 4,-2.7 2,-0.2 5,-0.2 0.931 110.8 47.0 -66.4 -47.0 14.6 58.0 66.2 129 139 A T H X S+ 0 0 53 -4,-2.6 4,-2.2 2,-0.2 -2,-0.2 0.941 114.8 47.4 -62.7 -44.6 14.8 54.3 67.0 130 140 A L H X S+ 0 0 33 -4,-2.3 4,-2.7 -5,-0.2 -2,-0.2 0.925 113.3 47.0 -60.0 -45.1 12.3 53.5 64.2 131 141 A T H X S+ 0 0 0 -4,-2.6 4,-2.7 1,-0.2 -1,-0.2 0.895 110.2 53.1 -67.8 -39.9 14.1 55.6 61.7 132 142 A R H X>S+ 0 0 45 -4,-2.7 4,-0.9 2,-0.2 5,-0.6 0.906 112.8 44.9 -60.0 -43.6 17.5 54.2 62.6 133 143 A Q H ><5S+ 0 0 97 -4,-2.2 3,-0.6 -5,-0.2 -2,-0.2 0.944 114.8 47.1 -66.3 -47.1 16.2 50.7 62.1 134 144 A R H 3<5S+ 0 0 125 -4,-2.7 -2,-0.2 1,-0.3 -1,-0.2 0.864 104.8 58.9 -67.0 -36.1 14.4 51.5 58.8 135 145 A L H ><5S- 0 0 11 -4,-2.7 3,-1.9 -5,-0.2 -1,-0.3 0.778 91.1-157.6 -60.9 -31.1 17.4 53.3 57.4 136 146 A A T <<5 - 0 0 55 -4,-0.9 -133,-0.1 -3,-0.6 -3,-0.1 0.799 63.7 -53.1 59.2 35.0 19.2 50.0 57.8 137 147 A G T 3 - 0 0 0 60,-2.7 4,-2.8 -2,-0.2 5,-0.3 -0.420 32.3-104.4 -76.6 157.0 19.9 76.0 71.8 148 158 A P H > S+ 0 0 1 0, 0.0 4,-2.8 0, 0.0 5,-0.2 0.910 117.5 46.0 -51.1 -50.9 18.9 77.7 75.1 149 159 A W H > S+ 0 0 0 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.950 113.8 48.4 -60.0 -46.6 18.9 81.3 73.9 150 160 A T H > S+ 0 0 0 1,-0.2 4,-1.6 2,-0.2 -1,-0.2 0.930 112.6 48.4 -63.2 -42.6 17.0 80.5 70.8 151 161 A L H X S+ 0 0 0 -4,-2.8 4,-2.2 1,-0.2 -1,-0.2 0.925 108.7 55.1 -59.9 -41.2 14.4 78.5 72.7 152 162 A M H X S+ 0 0 0 -4,-2.8 4,-2.4 -5,-0.3 5,-0.3 0.899 103.0 56.7 -55.7 -43.8 14.2 81.4 75.2 153 163 A T H X S+ 0 0 0 -4,-2.4 4,-2.7 1,-0.2 5,-0.4 0.915 108.7 45.0 -57.7 -45.2 13.4 83.8 72.4 154 164 A Y H X S+ 0 0 36 -4,-1.6 4,-1.9 1,-0.2 -1,-0.2 0.906 113.6 51.1 -63.8 -39.5 10.4 81.7 71.3 155 165 A M H < S+ 0 0 0 -4,-2.2 -53,-2.7 1,-0.2 -2,-0.2 0.831 120.3 33.1 -68.9 -33.9 9.2 81.3 74.9 156 166 A V H < S+ 0 0 0 -4,-2.4 -2,-0.2 -55,-0.2 -1,-0.2 0.864 124.0 41.7 -89.1 -46.6 9.3 85.0 75.6 157 167 A E H < S- 0 0 31 -4,-2.7 -3,-0.2 -5,-0.3 -2,-0.2 0.819 98.4-133.8 -71.6 -33.0 8.4 86.5 72.2 158 168 A G S < S- 0 0 8 -4,-1.9 -60,-2.1 -5,-0.4 2,-0.3 0.570 75.1 -10.6 87.3 13.7 5.7 83.9 71.7 159 169 A G S S- 0 0 9 -6,-0.4 -1,-0.2 -62,-0.2 -2,-0.2 -0.957 110.3 -21.6 159.7-162.4 6.9 83.3 68.1 160 170 A G - 0 0 64 -64,-0.4 2,-0.3 -2,-0.3 0, 0.0 -0.295 54.9-174.8 -69.3 157.4 9.3 84.8 65.6 161 171 A S - 0 0 35 -2,-0.1 -4,-0.0 1,-0.1 -3,-0.0 -0.983 31.7-140.4-153.3 146.1 10.4 88.5 65.8 162 172 A S S S+ 0 0 111 -2,-0.3 -1,-0.1 1,-0.1 -2,-0.0 0.646 106.3 19.9 -79.6 -15.0 12.6 90.8 63.7 163 173 A T S S- 0 0 76 0, 0.0 -1,-0.1 0, 0.0 5,-0.1 0.558 82.5-138.3-126.7 -20.7 14.2 92.3 66.8 164 174 A M > + 0 0 1 1,-0.1 4,-2.7 3,-0.1 5,-0.2 0.855 46.0 157.3 53.3 37.8 13.8 90.0 69.7 165 175 A A H > + 0 0 57 1,-0.2 4,-1.7 2,-0.2 -1,-0.1 0.828 67.0 46.2 -65.4 -37.7 13.1 93.1 71.7 166 176 A Q H > S+ 0 0 79 2,-0.2 4,-1.5 3,-0.1 -1,-0.2 0.928 115.3 45.6 -70.4 -44.6 11.1 91.4 74.5 167 177 A A H > S+ 0 0 0 1,-0.2 4,-1.6 2,-0.2 -2,-0.2 0.905 115.5 46.8 -67.5 -38.7 13.7 88.6 74.9 168 178 A K H X S+ 0 0 61 -4,-2.7 4,-2.1 2,-0.2 -1,-0.2 0.839 106.1 58.7 -70.2 -32.9 16.6 91.1 74.9 169 179 A R H X S+ 0 0 143 -4,-1.7 4,-2.4 -5,-0.2 5,-0.5 0.823 104.4 53.3 -62.5 -32.7 14.7 93.3 77.4 170 180 A W H X S+ 0 0 5 -4,-1.5 4,-2.3 3,-0.2 8,-0.3 0.928 106.9 51.3 -62.6 -47.9 14.8 90.2 79.6 171 181 A L H < S+ 0 0 3 -4,-1.6 -2,-0.2 1,-0.2 -1,-0.2 0.894 119.8 33.9 -59.7 -40.5 18.5 90.0 79.2 172 182 A Y H < S+ 0 0 164 -4,-2.1 -1,-0.2 2,-0.1 -2,-0.2 0.862 131.9 28.4 -82.9 -36.6 19.1 93.6 80.2 173 183 A Q H < S+ 0 0 125 -4,-2.4 -3,-0.2 -5,-0.2 -2,-0.2 0.727 131.9 32.2 -97.7 -30.6 16.3 94.2 82.7 174 184 A R X + 0 0 88 -4,-2.3 4,-2.4 -5,-0.5 5,-0.2 -0.444 66.3 151.2-122.7 54.9 16.0 90.6 84.1 175 185 A P H > S+ 0 0 52 0, 0.0 4,-2.6 0, 0.0 5,-0.2 0.890 75.4 49.5 -58.1 -38.9 19.5 89.1 83.9 176 186 A Q H > S+ 0 0 171 2,-0.2 4,-2.2 1,-0.2 5,-0.1 0.944 113.3 44.0 -66.7 -46.9 18.9 86.8 86.9 177 187 A A H > S+ 0 0 3 2,-0.2 4,-2.7 1,-0.2 -1,-0.2 0.849 112.5 55.3 -65.1 -34.1 15.6 85.4 85.7 178 188 A S H X S+ 0 0 0 -4,-2.4 4,-2.8 -8,-0.3 5,-0.2 0.951 108.3 46.3 -64.1 -49.0 17.1 85.1 82.2 179 189 A H H X S+ 0 0 66 -4,-2.6 4,-2.3 1,-0.2 -2,-0.2 0.895 111.5 53.9 -59.7 -37.0 20.0 83.0 83.6 180 190 A Q H X S+ 0 0 93 -4,-2.2 4,-2.4 1,-0.2 -2,-0.2 0.944 111.3 44.3 -62.3 -49.7 17.4 80.9 85.5 181 191 A L H X S+ 0 0 0 -4,-2.7 4,-2.8 2,-0.2 -2,-0.2 0.925 112.8 50.9 -57.6 -48.3 15.4 80.2 82.3 182 192 A L H X S+ 0 0 0 -4,-2.8 4,-2.2 1,-0.2 -2,-0.2 0.873 110.7 50.0 -62.2 -34.6 18.6 79.4 80.3 183 193 A R H X S+ 0 0 92 -4,-2.3 4,-2.9 -5,-0.2 -1,-0.2 0.919 108.8 51.3 -69.4 -43.4 19.7 77.0 83.0 184 194 A I H X S+ 0 0 24 -4,-2.4 4,-1.6 1,-0.2 5,-0.2 0.946 112.4 47.3 -54.8 -49.3 16.2 75.3 83.0 185 195 A L H X S+ 0 0 0 -4,-2.8 4,-2.8 1,-0.2 3,-0.2 0.920 112.4 48.7 -60.8 -43.6 16.5 74.9 79.2 186 196 A T H X S+ 0 0 0 -4,-2.2 4,-2.2 1,-0.2 -1,-0.2 0.928 110.2 51.0 -60.0 -47.1 20.1 73.6 79.4 187 197 A D H < S+ 0 0 54 -4,-2.9 -1,-0.2 1,-0.2 -2,-0.2 0.725 114.8 44.2 -67.3 -23.7 19.0 71.1 82.1 188 198 A A H X S+ 0 0 0 -4,-1.6 4,-1.6 -3,-0.2 -1,-0.2 0.848 112.3 52.1 -81.9 -39.9 16.1 69.9 79.9 189 199 A L H X S+ 0 0 0 -4,-2.8 4,-3.0 -5,-0.2 5,-0.3 0.840 101.3 59.7 -67.5 -40.0 18.2 69.8 76.7 190 200 A V H X S+ 0 0 0 -4,-2.2 4,-2.7 1,-0.2 5,-0.2 0.977 109.9 39.7 -58.1 -57.6 21.0 67.6 78.1 191 201 A P H > S+ 0 0 19 0, 0.0 4,-2.4 0, 0.0 -1,-0.2 0.853 116.2 53.8 -62.4 -33.1 18.9 64.6 79.0 192 202 A Y H X S+ 0 0 2 -4,-1.6 4,-1.8 2,-0.2 -2,-0.2 0.962 111.3 43.9 -61.9 -49.6 16.9 65.0 75.8 193 203 A L H X S+ 0 0 2 -4,-3.0 4,-1.7 2,-0.2 -3,-0.2 0.922 113.7 50.2 -64.3 -41.6 20.0 65.0 73.6 194 204 A V H X S+ 0 0 19 -4,-2.7 4,-2.8 -5,-0.3 3,-0.3 0.938 109.8 51.7 -59.7 -45.4 21.5 62.1 75.5 195 205 A G H X S+ 0 0 14 -4,-2.4 4,-2.4 1,-0.2 -1,-0.2 0.848 104.2 57.2 -62.8 -31.2 18.2 60.2 75.0 196 206 A Q H <>S+ 0 0 1 -4,-1.8 5,-2.5 2,-0.2 4,-0.4 0.903 110.0 44.3 -65.6 -37.3 18.3 60.9 71.3 197 207 A V H ><5S+ 0 0 15 -4,-1.7 3,-1.5 -3,-0.3 -2,-0.2 0.930 111.3 52.7 -71.8 -44.6 21.7 59.2 71.2 198 208 A V H 3<5S+ 0 0 87 -4,-2.8 -2,-0.2 1,-0.3 -1,-0.2 0.895 108.3 52.8 -55.6 -40.5 20.5 56.3 73.4 199 209 A A T 3<5S- 0 0 8 -4,-2.4 -1,-0.3 -5,-0.2 -2,-0.2 0.591 136.3 -81.1 -71.4 -14.7 17.6 55.9 70.9 200 210 A G T < 5S+ 0 0 1 -3,-1.5 -59,-0.3 -4,-0.4 -3,-0.2 0.363 74.8 147.2 133.9 -8.8 19.9 55.7 67.9 201 211 A A < - 0 0 3 -5,-2.5 -1,-0.3 -6,-0.1 -59,-0.2 -0.418 27.9-164.9 -60.0 139.4 21.1 59.2 66.8 202 212 A Q S S+ 0 0 21 -61,-3.0 2,-0.3 1,-0.2 -60,-0.2 0.350 71.9 14.2-109.3 -3.1 24.6 59.1 65.4 203 213 A A E -c 142 0A 0 -62,-0.8 -60,-2.9 43,-0.2 2,-0.4 -0.936 68.1-142.3-162.7 162.4 25.3 62.9 65.5 204 214 A L E -cd 143 248A 2 43,-2.0 45,-2.6 -2,-0.3 2,-0.5 -0.998 6.3-163.5-135.3 135.6 23.6 65.9 67.1 205 215 A Q E -cd 144 249A 1 -62,-2.2 -60,-1.7 -2,-0.4 2,-0.6 -0.979 7.2-155.1-120.0 133.1 23.1 69.5 65.9 206 216 A L E -cd 145 250A 3 43,-3.2 45,-2.4 -2,-0.5 2,-0.8 -0.925 12.9-147.3-105.1 120.5 22.2 72.3 68.2 207 217 A F E +cd 146 251A 25 -62,-2.6 -60,-2.7 -2,-0.6 2,-0.9 -0.793 21.6 176.4 -94.5 103.8 20.4 75.2 66.4 208 218 A E E > + d 0 252A 0 43,-2.8 3,-1.4 -2,-0.8 45,-1.1 -0.609 20.0 161.3 -95.7 68.8 21.2 78.6 67.8 209 219 A S T 3 + 0 0 22 -2,-0.9 3,-0.3 1,-0.3 -1,-0.2 0.709 66.8 49.8 -65.5 -21.9 19.0 80.1 65.0 210 220 A H T > S+ 0 0 22 -3,-0.2 3,-1.2 1,-0.2 4,-0.3 0.128 72.7 114.4-109.6 19.6 18.5 83.4 66.8 211 221 A A G X + 0 0 0 -3,-1.4 3,-1.8 1,-0.2 -1,-0.2 0.828 64.3 68.8 -54.1 -38.1 22.2 84.2 67.6 212 222 A G G 3 S+ 0 0 30 41,-1.2 -1,-0.2 1,-0.3 42,-0.1 0.679 84.1 67.6 -67.3 -21.7 22.4 87.2 65.3 213 223 A H G < S+ 0 0 55 -3,-1.2 2,-0.3 2,-0.0 -1,-0.3 0.709 94.7 71.7 -70.3 -21.2 20.2 89.4 67.4 214 224 A L S < S- 0 0 4 -3,-1.8 -46,-0.0 -4,-0.3 0, 0.0 -0.697 76.5-140.1 -91.0 143.6 22.8 89.4 70.1 215 225 A G > - 0 0 35 -2,-0.3 4,-2.0 42,-0.0 5,-0.2 -0.250 42.0 -87.9 -74.7-176.3 26.1 91.2 69.8 216 226 A P H > S+ 0 0 65 0, 0.0 4,-2.5 0, 0.0 5,-0.2 0.889 124.8 54.6 -57.7 -43.1 29.3 89.6 71.1 217 227 A Q H > S+ 0 0 167 1,-0.2 4,-1.5 2,-0.2 5,-0.1 0.936 115.0 37.9 -65.2 -46.8 28.9 91.0 74.7 218 228 A L H >>S+ 0 0 10 2,-0.2 4,-2.7 1,-0.2 5,-0.5 0.888 115.8 54.1 -72.3 -39.0 25.3 89.5 75.2 219 229 A F H X>S+ 0 0 0 -4,-2.0 5,-3.0 1,-0.2 4,-1.8 0.924 110.0 46.6 -58.5 -46.2 26.1 86.4 73.3 220 230 A N H <5S+ 0 0 61 -4,-2.5 -1,-0.2 1,-0.2 -2,-0.2 0.845 118.1 42.9 -66.5 -31.4 29.1 85.7 75.5 221 231 A K H <5S+ 0 0 134 -4,-1.5 -2,-0.2 -5,-0.2 -1,-0.2 0.879 131.8 14.7 -77.4 -43.4 27.1 86.4 78.6 222 232 A F H <5S+ 0 0 5 -4,-2.7 -3,-0.2 -5,-0.1 -2,-0.2 0.600 130.8 31.9-117.1 -25.2 23.8 84.6 77.9 223 233 A A T X S+ 0 0 42 0, 0.0 4,-2.0 0, 0.0 -1,-0.2 0.896 112.5 43.5 -57.1 -39.4 27.9 79.5 78.5 226 236 A Y H > S+ 0 0 12 -3,-0.4 4,-2.5 2,-0.2 -2,-0.2 0.846 110.0 55.4 -78.6 -34.5 24.9 77.3 77.9 227 237 A I H X S+ 0 0 0 -4,-2.0 4,-1.7 1,-0.2 -1,-0.2 0.955 112.7 44.7 -56.9 -46.6 26.1 76.2 74.4 228 238 A R H X S+ 0 0 122 -4,-2.6 4,-2.3 1,-0.2 -2,-0.2 0.899 111.2 52.1 -63.4 -43.4 29.3 75.0 76.1 229 239 A D H X S+ 0 0 42 -4,-2.0 4,-2.7 1,-0.2 5,-0.3 0.886 105.7 56.0 -64.8 -40.3 27.5 73.4 79.1 230 240 A V H X S+ 0 0 0 -4,-2.5 4,-2.5 1,-0.2 5,-0.3 0.962 111.4 42.1 -57.4 -50.6 25.2 71.4 76.6 231 241 A A H X S+ 0 0 1 -4,-1.7 4,-2.1 34,-0.2 5,-0.2 0.921 115.5 49.3 -62.6 -46.5 28.2 69.8 74.8 232 242 A K H X S+ 0 0 159 -4,-2.3 4,-2.1 33,-0.2 -1,-0.2 0.945 116.2 41.3 -60.6 -48.0 30.2 69.1 78.0 233 243 A Q H X S+ 0 0 51 -4,-2.7 4,-2.5 2,-0.2 5,-0.2 0.857 112.0 53.4 -73.7 -38.3 27.3 67.5 79.8 234 244 A V H X S+ 0 0 0 -4,-2.5 4,-2.3 -5,-0.3 5,-0.2 0.954 111.5 46.4 -60.0 -48.1 26.0 65.5 76.9 235 245 A K H X S+ 0 0 48 -4,-2.1 4,-2.3 -5,-0.3 -2,-0.2 0.933 113.1 51.2 -60.3 -40.2 29.5 64.0 76.3 236 246 A A H X S+ 0 0 20 -4,-2.1 4,-2.2 -5,-0.2 -2,-0.2 0.925 110.6 46.4 -63.3 -49.3 29.8 63.2 80.0 237 247 A R H X S+ 0 0 97 -4,-2.5 4,-1.6 2,-0.2 -1,-0.2 0.892 112.3 50.9 -62.1 -40.1 26.6 61.4 80.4 238 248 A L H <>S+ 0 0 1 -4,-2.3 5,-2.3 -5,-0.2 3,-0.3 0.946 111.1 47.5 -65.0 -44.1 27.1 59.4 77.3 239 249 A R H ><5S+ 0 0 146 -4,-2.3 3,-1.2 1,-0.2 -1,-0.2 0.887 111.6 51.6 -62.0 -39.4 30.6 58.2 78.4 240 250 A E H 3<5S+ 0 0 151 -4,-2.2 -1,-0.2 1,-0.3 -2,-0.2 0.763 105.4 55.4 -71.3 -25.9 29.2 57.4 81.8 241 251 A A T 3<5S- 0 0 69 -4,-1.6 -1,-0.3 -3,-0.3 -2,-0.2 0.370 120.0-108.6 -86.5 4.4 26.4 55.3 80.3 242 252 A G T < 5S+ 0 0 69 -3,-1.2 2,-0.2 1,-0.3 -3,-0.2 0.634 78.6 127.5 79.1 16.2 29.0 53.2 78.4 243 253 A L < - 0 0 69 -5,-2.3 -1,-0.3 -6,-0.2 -2,-0.1 -0.573 65.2-105.5-104.2 162.8 28.1 54.7 75.1 244 254 A A - 0 0 76 -2,-0.2 2,-0.1 -3,-0.1 -5,-0.0 -0.716 34.6-122.8 -83.1 120.5 30.1 56.3 72.4 245 255 A P - 0 0 43 0, 0.0 -10,-0.1 0, 0.0 3,-0.0 -0.499 28.1-139.4 -56.6 150.0 29.8 60.2 72.2 246 256 A V - 0 0 14 -2,-0.1 -43,-0.2 1,-0.1 2,-0.1 -0.652 28.4 -84.6-108.4 158.7 28.7 61.4 68.8 247 257 A P - 0 0 2 0, 0.0 -43,-2.0 0, 0.0 2,-0.4 -0.483 45.5-148.8 -66.5 139.6 29.9 64.4 66.8 248 258 A M E -d 204 0A 5 -45,-0.2 21,-2.0 -2,-0.1 20,-0.8 -0.924 6.8-157.6-118.5 139.4 28.1 67.5 67.8 249 259 A I E -de 205 269A 1 -45,-2.6 -43,-3.2 -2,-0.4 2,-0.5 -0.956 1.7-159.5-118.3 128.8 27.4 70.5 65.5 250 260 A I E -de 206 270A 0 19,-2.3 21,-3.1 -2,-0.4 2,-0.6 -0.958 8.5-172.7-107.0 124.5 26.8 74.0 66.7 251 261 A F E -de 207 271A 1 -45,-2.4 -43,-2.8 -2,-0.5 2,-0.8 -0.932 5.3-180.0-120.1 104.7 25.0 76.2 64.1 252 262 A A E > -d 208 0A 6 19,-0.8 3,-2.0 -2,-0.6 21,-0.3 -0.867 21.2-147.0-103.2 98.3 24.7 79.9 65.2 253 263 A K T 3 S+ 0 0 31 -45,-1.1 -41,-1.2 -2,-0.8 -42,-0.1 -0.425 85.3 8.1 -69.1 135.3 22.8 81.6 62.3 254 264 A D T 3 S+ 0 0 59 -43,-0.2 3,-0.4 -2,-0.1 -1,-0.3 0.696 94.2 131.7 61.8 24.8 24.1 85.2 61.9 255 265 A G X + 0 0 1 -3,-2.0 3,-2.4 1,-0.2 4,-0.4 -0.026 10.6 131.5 -98.1 31.3 26.8 84.3 64.4 256 266 A H G > S+ 0 0 115 1,-0.3 3,-1.1 2,-0.2 4,-0.3 0.853 73.0 57.0 -45.1 -41.7 29.8 85.7 62.4 257 267 A F G 3 S+ 0 0 36 -3,-0.4 -1,-0.3 1,-0.2 4,-0.2 0.600 106.7 46.9 -72.1 -13.5 30.9 87.5 65.6 258 268 A A G <> S+ 0 0 0 -3,-2.4 4,-2.6 -6,-0.1 -1,-0.2 0.329 75.6 107.3-112.1 6.4 31.1 84.4 67.7 259 269 A L H <> S+ 0 0 7 -3,-1.1 4,-1.9 -4,-0.4 -1,-0.1 0.865 79.2 50.6 -62.2 -40.2 33.0 82.0 65.5 260 270 A E H 4 S+ 0 0 130 -4,-0.3 4,-0.3 1,-0.2 -1,-0.2 0.942 115.2 43.5 -60.9 -42.1 36.3 82.0 67.4 261 271 A E H >4 S+ 0 0 66 1,-0.2 3,-1.1 2,-0.2 -2,-0.2 0.847 111.0 54.9 -72.1 -36.5 34.4 81.3 70.7 262 272 A L H >< S+ 0 0 2 -4,-2.6 3,-1.4 1,-0.3 5,-0.5 0.829 100.2 60.8 -66.2 -31.5 32.2 78.6 69.0 263 273 A A T 3< S+ 0 0 8 -4,-1.9 -1,-0.3 1,-0.3 -2,-0.2 0.629 109.4 42.6 -69.1 -15.3 35.4 76.8 67.8 264 274 A Q T < S+ 0 0 132 -3,-1.1 -1,-0.3 -4,-0.3 -2,-0.2 0.016 88.9 95.3-116.0 20.2 36.4 76.4 71.4 265 275 A A S < S- 0 0 5 -3,-1.4 -34,-0.2 2,-0.1 -33,-0.2 0.475 103.8 -96.2 -98.0 3.1 33.0 75.4 72.7 266 276 A G S S+ 0 0 37 1,-0.3 2,-0.4 -3,-0.2 -18,-0.1 0.630 81.6 126.8 94.7 19.2 33.3 71.6 72.6 267 277 A Y - 0 0 8 -5,-0.5 -1,-0.3 1,-0.1 -18,-0.2 -0.873 53.3-148.2-107.1 136.0 31.7 70.9 69.2 268 278 A E S S+ 0 0 35 -20,-0.8 22,-2.5 -2,-0.4 2,-0.4 0.809 86.5 37.9 -65.6 -30.4 33.3 68.9 66.5 269 279 A V E -ef 249 290A 0 -21,-2.0 -19,-2.3 20,-0.2 2,-0.5 -0.979 63.6-158.4-132.7 131.9 31.6 71.0 63.8 270 280 A V E -ef 250 291A 0 20,-2.4 22,-2.2 -2,-0.4 2,-0.3 -0.974 19.8-146.8-107.7 120.0 30.7 74.7 63.5 271 281 A G E -ef 251 292A 3 -21,-3.1 -19,-0.8 -2,-0.5 2,-0.4 -0.675 14.4-152.9 -91.0 145.3 27.9 75.4 61.0 272 282 A L - 0 0 3 20,-2.5 22,-0.3 -2,-0.3 -19,-0.1 -0.924 10.3-132.8-123.2 142.9 27.9 78.6 59.0 273 283 A D > - 0 0 2 -2,-0.4 3,-1.0 -21,-0.3 56,-0.1 -0.343 38.8-102.7 -79.7 173.4 25.4 80.8 57.4 274 284 A W T 3 S+ 0 0 81 1,-0.2 22,-0.2 21,-0.1 -1,-0.1 0.493 110.8 72.8 -80.1 -6.1 25.9 82.1 53.8 275 285 A T T 3 S+ 0 0 77 53,-0.1 2,-0.6 2,-0.1 -1,-0.2 0.624 80.5 81.6 -84.8 -13.4 27.1 85.6 54.9 276 286 A V S < S- 0 0 12 -3,-1.0 18,-0.1 18,-0.1 -4,-0.0 -0.847 83.9-126.6 -96.8 124.4 30.4 84.4 56.2 277 287 A A > - 0 0 44 -2,-0.6 4,-2.3 1,-0.1 3,-0.5 -0.481 20.8-128.4 -66.7 129.9 33.1 83.9 53.5 278 288 A P H > S+ 0 0 12 0, 0.0 4,-2.6 0, 0.0 5,-0.2 0.884 107.0 51.9 -49.4 -43.8 34.5 80.4 53.9 279 289 A K H > S+ 0 0 130 1,-0.2 4,-1.8 2,-0.2 5,-0.1 0.888 110.2 48.4 -63.6 -37.4 38.1 81.5 54.1 280 290 A K H > S+ 0 0 135 -3,-0.5 4,-2.1 2,-0.2 -1,-0.2 0.903 110.5 51.5 -68.8 -37.6 37.3 84.1 56.8 281 291 A A H X S+ 0 0 0 -4,-2.3 4,-2.6 2,-0.2 5,-0.3 0.925 107.6 52.8 -61.9 -43.3 35.4 81.4 58.8 282 292 A R H X S+ 0 0 40 -4,-2.6 4,-2.0 1,-0.2 -1,-0.2 0.910 108.6 50.3 -59.3 -41.6 38.4 79.1 58.5 283 293 A E H < S+ 0 0 160 -4,-1.8 -1,-0.2 1,-0.2 -2,-0.2 0.918 112.9 47.7 -62.0 -42.9 40.7 81.8 59.9 284 294 A C H < S+ 0 0 55 -4,-2.1 -2,-0.2 1,-0.2 -1,-0.2 0.896 119.0 36.2 -64.5 -43.9 38.3 82.4 62.8 285 295 A V H < S- 0 0 6 -4,-2.6 4,-0.4 1,-0.2 3,-0.4 0.731 99.5-145.3 -89.3 -19.4 37.8 78.8 63.8 286 296 A G < - 0 0 31 -4,-2.0 -1,-0.2 -5,-0.3 -2,-0.1 -0.363 36.0 -52.2 80.7-165.0 41.3 77.5 63.2 287 297 A K S S+ 0 0 160 1,-0.1 -1,-0.2 -2,-0.1 -4,-0.0 0.422 116.2 57.9-100.5 0.6 42.5 74.1 61.9 288 298 A T S S+ 0 0 101 -3,-0.4 -1,-0.1 -25,-0.1 -2,-0.1 0.921 86.4 76.3 -92.1 -53.0 40.9 71.5 64.1 289 299 A V S S- 0 0 4 -4,-0.4 2,-0.3 -26,-0.1 -20,-0.2 -0.135 76.5-123.5 -67.3 152.7 37.2 72.0 63.9 290 300 A T E -f 269 0A 1 -22,-2.5 -20,-2.4 -277,-0.4 2,-0.4 -0.732 21.8-140.2 -88.0 138.8 35.1 70.9 60.9 291 301 A L E -fg 270 323A 0 31,-2.3 33,-2.5 -2,-0.3 2,-0.4 -0.826 12.8-161.1 -96.6 146.5 33.1 73.6 59.1 292 302 A Q E -fg 271 324A 1 -22,-2.2 -20,-2.5 -2,-0.4 2,-0.3 -0.982 36.8 -23.0-129.2 136.1 29.6 72.9 57.8 293 303 A G E + g 0 325A 1 31,-2.0 33,-0.9 -2,-0.4 35,-0.2 -0.926 32.2 159.9 136.3-157.8 27.7 74.9 55.1 294 304 A N E + g 0 326A 10 -22,-0.3 34,-0.3 -2,-0.3 33,-0.3 -0.856 21.3 130.8-145.1 31.2 27.2 77.3 53.6 295 305 A L E - g 0 327A 14 31,-1.7 33,-2.9 1,-0.1 34,-0.4 -0.275 63.8-105.1 -61.7 130.4 25.5 78.0 50.3 296 306 A D > - 0 0 54 -22,-0.2 3,-1.9 31,-0.2 4,-0.3 -0.301 27.8-138.5 -44.6 119.1 22.8 80.7 50.2 297 307 A P G > S+ 0 0 0 0, 0.0 3,-1.8 0, 0.0 -1,-0.2 0.868 102.4 62.4 -56.6 -32.1 19.6 78.6 50.1 298 308 A C G > S+ 0 0 41 1,-0.3 3,-2.1 2,-0.2 4,-0.2 0.669 82.0 80.2 -69.0 -17.4 18.3 81.1 47.6 299 309 A A G X S+ 0 0 12 -3,-1.9 3,-1.9 1,-0.3 -1,-0.3 0.747 78.4 71.7 -56.0 -24.6 21.1 80.1 45.2 300 310 A L G < S+ 0 0 1 -3,-1.8 36,-0.3 -4,-0.3 -1,-0.3 0.554 82.5 69.3 -73.3 -7.5 18.9 77.1 44.5 301 311 A Y G < S+ 0 0 104 -3,-2.1 -1,-0.3 34,-0.1 -2,-0.2 0.610 86.5 89.3 -75.3 -16.7 16.6 79.4 42.6 302 312 A A S < S- 0 0 24 -3,-1.9 -3,-0.0 -4,-0.2 2,-0.0 -0.204 96.2 -77.7 -75.5 170.3 19.3 79.7 40.0 303 313 A S > - 0 0 40 1,-0.1 4,-2.8 4,-0.0 5,-0.2 -0.280 41.8-109.2 -64.2 159.8 19.7 77.3 37.0 304 314 A E H > S+ 0 0 97 1,-0.2 4,-2.2 2,-0.2 5,-0.1 0.913 122.4 50.7 -57.7 -40.3 21.1 73.8 37.6 305 315 A E H > S+ 0 0 139 2,-0.2 4,-1.7 1,-0.2 -1,-0.2 0.903 110.3 47.8 -61.1 -45.6 24.2 74.9 35.7 306 316 A E H > S+ 0 0 89 2,-0.2 4,-2.6 1,-0.2 5,-0.2 0.909 108.7 55.1 -64.1 -42.3 24.6 78.1 37.8 307 317 A I H X S+ 0 0 0 -4,-2.8 4,-2.6 1,-0.2 -2,-0.2 0.938 106.1 52.4 -56.7 -45.4 24.1 76.0 41.0 308 318 A G H X S+ 0 0 26 -4,-2.2 4,-2.2 1,-0.2 -1,-0.2 0.886 110.7 47.0 -59.3 -38.7 27.0 73.8 39.9 309 319 A Q H X S+ 0 0 107 -4,-1.7 4,-2.1 2,-0.2 -1,-0.2 0.879 111.4 49.4 -70.4 -41.0 29.3 76.8 39.4 310 320 A L H X S+ 0 0 79 -4,-2.6 4,-2.3 2,-0.2 -2,-0.2 0.900 112.4 50.2 -63.1 -39.9 28.4 78.3 42.8 311 321 A V H X S+ 0 0 0 -4,-2.6 4,-2.7 -5,-0.2 5,-0.2 0.916 108.2 52.1 -63.8 -45.5 29.0 74.9 44.4 312 322 A K H X S+ 0 0 99 -4,-2.2 4,-2.2 1,-0.2 -2,-0.2 0.926 111.7 46.6 -54.5 -47.3 32.4 74.6 42.7 313 323 A Q H X S+ 0 0 102 -4,-2.1 4,-1.9 2,-0.2 -1,-0.2 0.906 111.4 51.2 -63.8 -43.0 33.4 78.1 44.0 314 324 A M H X S+ 0 0 10 -4,-2.3 4,-2.2 1,-0.2 5,-0.2 0.932 110.8 47.9 -59.6 -47.7 32.2 77.3 47.5 315 325 A L H X S+ 0 0 1 -4,-2.7 4,-2.1 1,-0.2 -1,-0.2 0.855 108.1 55.9 -64.9 -34.8 34.2 74.0 47.6 316 326 A D H < S+ 0 0 60 -4,-2.2 -1,-0.2 -5,-0.2 -2,-0.2 0.915 110.0 46.2 -60.1 -43.2 37.3 75.9 46.3 317 327 A D H < S+ 0 0 48 -4,-1.9 -2,-0.2 1,-0.2 -1,-0.2 0.897 116.1 43.0 -69.4 -40.3 37.1 78.3 49.2 318 328 A F H < S- 0 0 9 -4,-2.2 -1,-0.2 -5,-0.1 -2,-0.2 0.848 100.3-145.9 -72.1 -32.9 36.5 75.7 51.9 319 329 A G < - 0 0 18 -4,-2.1 -2,-0.1 -5,-0.2 -3,-0.1 0.033 31.1 -76.7 72.6 165.1 39.1 73.3 50.6 320 330 A P S S+ 0 0 30 0, 0.0 3,-0.4 0, 0.0 2,-0.2 0.810 101.9 79.8 -72.9 -26.8 38.8 69.5 50.8 321 331 A H S S+ 0 0 78 1,-0.2 -304,-0.1 -3,-0.1 3,-0.1 -0.483 96.4 4.9 -88.0 149.5 39.6 68.9 54.6 322 332 A R S S+ 0 0 33 -306,-0.3 -31,-2.3 -2,-0.2 2,-0.3 0.926 97.9 125.4 55.0 49.8 37.4 69.4 57.7 323 333 A Y E - g 0 291A 3 -3,-0.4 2,-0.4 -33,-0.2 -31,-0.2 -0.980 40.5-175.5-150.4 132.5 34.3 70.2 55.7 324 334 A I E - g 0 292A 0 -33,-2.5 -31,-2.0 -2,-0.3 -301,-0.2 -0.999 30.6-131.0-123.1 123.9 30.7 69.0 55.4 325 335 A A E +ag 23 293A 0 -303,-2.2 -301,-1.7 -2,-0.4 2,-0.3 -0.470 44.2 134.0 -78.8 141.9 28.6 70.7 52.6 326 336 A N E - g 0 294A 0 -33,-0.9 -31,-1.7 -303,-0.2 -301,-0.2 -0.940 54.7 -83.7-163.8 174.4 25.2 72.1 53.4 327 337 A L E - g 0 295A 0 -2,-0.3 -31,-0.2 -303,-0.3 -55,-0.2 -0.387 40.7-109.9 -76.5 171.9 23.2 75.3 52.8 328 338 A G S S- 0 0 0 -33,-2.9 2,-0.3 -34,-0.3 -32,-0.1 0.509 97.1 -9.0 -80.4 -9.0 23.5 78.3 54.9 329 339 A H S S- 0 0 46 -34,-0.4 -303,-0.3 -56,-0.1 -2,-0.1 -0.914 101.2 -51.4-170.7-177.3 20.0 77.8 56.4 330 340 A G - 0 0 5 -2,-0.3 -303,-0.3 1,-0.1 -2,-0.1 -0.301 60.7 -93.0 -73.0 155.5 17.1 75.5 55.6 331 341 A L - 0 0 8 -305,-2.1 -300,-0.1 1,-0.1 -1,-0.1 -0.284 41.7-124.5 -56.0 144.8 15.4 75.0 52.2 332 342 A Y > - 0 0 72 -35,-0.1 3,-1.7 -302,-0.1 -1,-0.1 -0.671 19.9-112.2 -96.0 155.1 12.4 77.2 51.5 333 343 A P T 3 S+ 0 0 55 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.691 111.3 54.8 -62.7 -22.5 8.9 75.9 50.6 334 344 A D T 3 S+ 0 0 114 2,-0.1 2,-0.1 -302,-0.0 -3,-0.0 0.242 81.6 119.2 -96.0 14.7 9.0 77.2 47.0 335 345 A M < - 0 0 8 -3,-1.7 -34,-0.1 1,-0.1 3,-0.0 -0.421 67.3-114.5 -85.3 154.9 12.2 75.5 46.0 336 346 A D >> - 0 0 71 -36,-0.3 3,-1.5 1,-0.1 4,-1.4 -0.798 11.5-143.4 -91.6 120.5 12.5 72.9 43.2 337 347 A P H 3> S+ 0 0 16 0, 0.0 4,-2.4 0, 0.0 5,-0.2 0.842 101.2 60.8 -51.5 -35.4 13.4 69.4 44.3 338 348 A E H 3> S+ 0 0 105 1,-0.2 4,-1.7 2,-0.2 5,-0.1 0.817 102.8 50.5 -61.9 -31.6 15.5 69.1 41.0 339 349 A H H <> S+ 0 0 32 -3,-1.5 4,-1.8 2,-0.2 -1,-0.2 0.812 107.2 53.1 -74.7 -31.7 17.7 72.0 42.1 340 350 A V H X S+ 0 0 0 -4,-1.4 4,-2.3 2,-0.2 -2,-0.2 0.936 109.5 50.7 -63.3 -43.7 18.2 70.4 45.5 341 351 A G H X S+ 0 0 9 -4,-2.4 4,-2.7 1,-0.2 5,-0.2 0.900 107.5 52.7 -57.8 -42.6 19.3 67.3 43.5 342 352 A A H X S+ 0 0 14 -4,-1.7 4,-1.9 2,-0.2 -1,-0.2 0.881 107.8 51.6 -61.8 -40.5 21.7 69.5 41.4 343 353 A F H X S+ 0 0 0 -4,-1.8 4,-2.0 2,-0.2 -2,-0.2 0.948 111.6 46.2 -57.9 -51.9 23.2 70.9 44.6 344 354 A V H X S+ 0 0 0 -4,-2.3 4,-2.0 1,-0.2 -2,-0.2 0.938 113.9 47.5 -60.3 -49.3 23.8 67.4 46.0 345 355 A D H X S+ 0 0 94 -4,-2.7 4,-2.9 1,-0.2 -1,-0.2 0.864 110.8 53.5 -62.6 -35.0 25.3 66.0 42.7 346 356 A A H X S+ 0 0 14 -4,-1.9 4,-2.5 -5,-0.2 5,-0.4 0.875 106.0 50.1 -71.0 -39.1 27.5 69.1 42.4 347 357 A V H X S+ 0 0 0 -4,-2.0 4,-2.2 2,-0.2 -326,-0.4 0.941 114.9 46.0 -61.5 -45.8 29.1 68.7 45.8 348 358 A H H X S+ 0 0 30 -4,-2.0 4,-1.5 -5,-0.2 -2,-0.2 0.958 116.2 44.4 -60.3 -51.9 29.8 65.1 45.0 349 359 A K H X S+ 0 0 156 -4,-2.9 4,-1.8 1,-0.2 -2,-0.2 0.949 118.7 39.6 -61.2 -53.8 31.2 65.8 41.6 350 360 A H H X S+ 0 0 21 -4,-2.5 4,-2.1 1,-0.2 -1,-0.2 0.868 110.2 57.7 -69.5 -35.5 33.4 68.8 42.4 351 361 A S H X S+ 0 0 0 -4,-2.2 4,-0.7 -5,-0.4 -1,-0.2 0.872 108.5 48.2 -64.8 -34.2 34.7 67.5 45.7 352 362 A R H >X S+ 0 0 134 -4,-1.5 4,-1.0 -5,-0.2 3,-1.0 0.933 111.6 49.0 -68.5 -44.0 36.1 64.4 43.9 353 363 A L H 3< S+ 0 0 114 -4,-1.8 3,-0.2 1,-0.2 -2,-0.2 0.820 106.3 58.6 -59.8 -32.0 37.7 66.6 41.2 354 364 A L H 3< S+ 0 0 57 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.720 106.8 47.5 -75.4 -20.0 39.2 68.7 43.9 355 365 A R H << 0 0 61 -3,-1.0 -1,-0.2 -4,-0.7 -2,-0.2 0.669 360.0 360.0 -92.0 -23.0 41.0 65.7 45.4 356 366 A Q < 0 0 202 -4,-1.0 -1,-0.3 -3,-0.2 -2,-0.0 -0.795 360.0 360.0-162.0 360.0 42.6 64.2 42.3