==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 12-SEP-07 2R9F . COMPND 2 MOLECULE: CALPAIN-1 CATALYTIC SUBUNIT; . SOURCE 2 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS; . AUTHOR J.QIAN,R.L.CAMPBELL,P.L.DAVIES . 323 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15379.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 208 64.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 5 1.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 53 16.4 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 28 8.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 42 13.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 63 19.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 0 4 0 0 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 2 1 0 2 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 33 A N 0 0 205 0, 0.0 126,-0.1 0, 0.0 128,-0.1 0.000 360.0 360.0 360.0 140.9 -18.9 2.5 -10.3 2 34 A A - 0 0 17 126,-0.1 126,-0.2 1,-0.1 2,-0.2 -0.314 360.0-123.3 -59.5 142.8 -18.1 4.7 -7.3 3 35 A I E -a 128 0A 88 124,-2.1 126,-2.4 1,-0.1 2,-0.5 -0.596 34.0 -96.2 -90.6 157.0 -18.4 8.4 -8.1 4 36 A K E > -a 129 0A 102 124,-0.2 3,-2.0 -2,-0.2 2,-0.2 -0.601 29.8-125.1 -85.3 122.7 -15.3 10.6 -7.4 5 37 A Y G > S- 0 0 40 124,-2.7 3,-2.1 -2,-0.5 126,-0.2 -0.411 96.0 -6.5 -61.4 124.9 -15.1 12.5 -4.2 6 38 A L G 3 S- 0 0 108 1,-0.3 -1,-0.3 -2,-0.2 3,-0.1 0.604 121.7 -75.9 64.2 10.6 -14.6 16.3 -5.0 7 39 A G G < S+ 0 0 57 -3,-2.0 2,-0.4 1,-0.3 -1,-0.3 0.571 87.6 153.8 77.6 8.6 -14.3 15.3 -8.6 8 40 A Q < - 0 0 31 -3,-2.1 2,-0.8 121,-0.2 -1,-0.3 -0.606 33.8-150.5 -77.0 128.7 -10.8 14.0 -8.0 9 41 A D > - 0 0 57 -2,-0.4 4,-3.1 1,-0.2 5,-0.3 -0.849 7.2-163.0-109.1 99.9 -10.0 11.3 -10.6 10 42 A Y H > S+ 0 0 36 -2,-0.8 4,-2.7 1,-0.2 5,-0.2 0.921 87.9 40.8 -45.6 -60.7 -7.5 8.6 -9.4 11 43 A E H > S+ 0 0 91 1,-0.2 4,-2.5 2,-0.2 -1,-0.2 0.894 117.7 48.2 -65.3 -38.1 -6.5 7.0 -12.7 12 44 A N H > S+ 0 0 79 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.921 114.1 45.8 -65.6 -45.3 -6.3 10.4 -14.5 13 45 A L H X S+ 0 0 31 -4,-3.1 4,-2.6 2,-0.2 -2,-0.2 0.913 114.6 48.9 -63.4 -42.4 -4.2 12.0 -11.7 14 46 A R H X S+ 0 0 45 -4,-2.7 4,-2.3 -5,-0.3 -2,-0.2 0.955 112.9 46.2 -62.3 -49.6 -1.9 9.0 -11.5 15 47 A A H X S+ 0 0 40 -4,-2.5 4,-2.4 -5,-0.2 -2,-0.2 0.899 114.2 48.5 -63.2 -40.4 -1.4 8.9 -15.3 16 48 A R H X S+ 0 0 112 -4,-2.4 4,-2.3 2,-0.2 -1,-0.2 0.889 110.1 50.5 -70.8 -38.3 -0.7 12.6 -15.5 17 49 A C H <>S+ 0 0 16 -4,-2.6 5,-2.2 2,-0.2 4,-0.5 0.913 111.5 49.8 -61.3 -41.4 1.7 12.6 -12.6 18 50 A L H ><5S+ 0 0 73 -4,-2.3 3,-1.0 1,-0.2 -2,-0.2 0.929 112.1 46.6 -63.6 -45.0 3.6 9.7 -14.3 19 51 A Q H 3<5S+ 0 0 162 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.874 113.6 49.0 -62.3 -40.1 3.7 11.6 -17.6 20 52 A N T 3<5S- 0 0 108 -4,-2.3 -1,-0.2 -5,-0.2 -2,-0.2 0.411 110.6-122.1 -84.1 -1.3 4.9 14.8 -15.9 21 53 A G T < 5S+ 0 0 70 -3,-1.0 2,-0.3 -4,-0.5 -3,-0.2 0.745 73.1 110.9 70.3 27.4 7.6 12.9 -13.9 22 54 A V < - 0 0 78 -5,-2.2 2,-0.4 -6,-0.2 -1,-0.2 -0.811 67.1-114.4-127.5 164.8 6.3 14.0 -10.5 23 55 A L - 0 0 65 -2,-0.3 92,-0.2 -3,-0.1 110,-0.1 -0.817 43.7 -98.0 -96.7 144.0 4.6 12.4 -7.4 24 56 A F - 0 0 15 90,-3.0 2,-0.4 -2,-0.4 110,-0.3 -0.294 33.0-170.8 -59.8 139.5 1.0 13.4 -6.5 25 57 A Q - 0 0 123 108,-0.1 2,-0.8 109,-0.1 91,-0.1 -0.993 24.9-128.5-129.8 128.3 0.4 16.1 -3.8 26 58 A D > - 0 0 0 -2,-0.4 3,-1.5 3,-0.3 107,-0.1 -0.655 19.3-171.0 -89.4 105.0 -3.2 16.4 -2.8 27 59 A D T 3 S+ 0 0 155 -2,-0.8 -1,-0.2 1,-0.2 0, 0.0 0.762 89.7 57.7 -57.8 -26.3 -4.6 19.9 -2.9 28 60 A A T 3 S+ 0 0 42 1,-0.3 -1,-0.2 -3,-0.0 -2,-0.1 0.552 127.5 11.6 -84.2 -10.5 -7.7 18.6 -1.1 29 61 A F S < S- 0 0 6 -3,-1.5 -3,-0.3 140,-0.0 104,-0.3 -0.411 90.6-169.7-164.0 69.1 -5.8 17.2 1.9 30 62 A P - 0 0 44 0, 0.0 2,-2.1 0, 0.0 5,-0.2 -0.187 36.2 -98.0 -76.4 165.8 -2.3 18.6 1.7 31 63 A P S S+ 0 0 32 0, 0.0 2,-0.3 0, 0.0 22,-0.2 -0.438 87.2 102.4 -82.2 66.3 0.8 17.6 3.8 32 64 A V S >> S- 0 0 68 -2,-2.1 3,-2.0 20,-0.1 4,-0.7 -0.891 88.7 -88.7-142.9 171.5 0.5 20.5 6.3 33 65 A S H >> S+ 0 0 33 1,-0.3 4,-2.3 -2,-0.3 3,-0.9 0.781 116.1 67.2 -60.5 -32.8 -0.7 21.0 9.8 34 66 A H H 34 S+ 0 0 135 1,-0.3 -1,-0.3 2,-0.2 7,-0.0 0.717 98.3 54.5 -61.6 -23.9 -4.4 21.7 8.9 35 67 A S H <4 S+ 0 0 4 -3,-2.0 135,-2.0 -5,-0.2 -1,-0.3 0.728 108.3 50.2 -76.5 -26.1 -4.6 18.0 7.7 36 68 A L H << S- 0 0 3 -3,-0.9 135,-2.5 -4,-0.7 2,-0.3 0.941 121.2 -86.7 -70.8 -52.6 -3.4 16.9 11.2 37 69 A G < - 0 0 3 -4,-2.3 -1,-0.3 4,-0.4 133,-0.0 -0.973 20.4-100.3 170.3-157.5 -5.8 18.9 13.2 38 70 A F S S+ 0 0 139 -2,-0.3 4,-0.1 4,-0.2 6,-0.1 0.470 98.3 7.5-141.5 -19.6 -6.9 22.2 14.9 39 71 A K S > S+ 0 0 156 3,-0.1 3,-1.5 4,-0.1 5,-0.1 0.383 135.5 24.2-135.5 -81.2 -6.3 21.9 18.7 40 72 A E T 3 S+ 0 0 111 1,-0.3 7,-0.5 5,-0.1 8,-0.3 0.811 144.3 27.5 -61.9 -31.0 -4.5 18.9 20.0 41 73 A L T 3 S+ 0 0 10 6,-0.1 -4,-0.4 5,-0.1 -1,-0.3 -0.145 99.1 133.1-121.4 35.9 -2.9 18.6 16.5 42 74 A G S X S- 0 0 3 -3,-1.5 3,-1.8 -6,-0.1 6,-0.3 -0.304 74.8 -91.0 -83.2 172.6 -3.1 22.3 15.6 43 75 A P T 3 S+ 0 0 52 0, 0.0 -1,-0.1 0, 0.0 -10,-0.1 0.731 124.9 41.0 -56.5 -27.0 -0.4 24.5 14.0 44 76 A N T 3 S+ 0 0 133 -5,-0.1 2,-0.3 -6,-0.1 -6,-0.0 0.053 91.8 114.5-113.2 26.6 0.9 25.6 17.5 45 77 A S S <> S- 0 0 17 -3,-1.8 4,-2.1 1,-0.1 -5,-0.1 -0.663 71.1-123.1-105.0 152.0 0.7 22.3 19.4 46 78 A S H > S+ 0 0 113 -2,-0.3 4,-0.8 1,-0.2 -1,-0.1 0.876 112.6 50.1 -56.8 -41.8 3.4 20.1 20.9 47 79 A K H >> S+ 0 0 128 -7,-0.5 4,-0.6 1,-0.2 3,-0.6 0.907 109.5 50.4 -65.4 -42.5 2.3 17.1 18.9 48 80 A T H >4 S+ 0 0 13 -8,-0.3 3,-1.4 -6,-0.3 -2,-0.2 0.926 99.7 65.4 -63.4 -44.4 2.3 19.0 15.6 49 81 A Y H 3< S+ 0 0 153 -4,-2.1 -1,-0.2 1,-0.3 -2,-0.2 0.720 102.6 45.1 -53.9 -34.1 5.8 20.4 16.0 50 82 A G H << S+ 0 0 31 -4,-0.8 90,-0.3 -3,-0.6 2,-0.3 0.639 91.5 101.9 -84.0 -15.1 7.6 17.0 15.9 51 83 A I << - 0 0 22 -3,-1.4 2,-0.4 -4,-0.6 88,-0.2 -0.506 46.6-175.6 -79.9 132.5 5.7 15.6 12.9 52 84 A K E -C 138 0B 138 86,-2.8 86,-2.0 -2,-0.3 2,-0.5 -0.990 25.7-124.7-123.7 138.3 7.2 15.5 9.4 53 85 A W E +C 137 0B 40 -2,-0.4 2,-0.3 84,-0.2 82,-0.1 -0.711 39.4 167.1 -84.2 122.9 5.3 14.3 6.3 54 86 A K E -C 136 0B 66 82,-2.4 82,-2.4 -2,-0.5 -2,-0.0 -0.993 32.2-125.3-138.9 142.3 7.1 11.5 4.5 55 87 A R >> - 0 0 14 -2,-0.3 3,-2.3 80,-0.2 4,-1.4 -0.577 28.2-118.8 -79.6 149.9 6.2 9.0 1.7 56 88 A P H 3> S+ 0 0 0 0, 0.0 4,-2.3 0, 0.0 -1,-0.1 0.815 118.6 59.7 -56.9 -26.7 6.8 5.2 2.3 57 89 A T H 34 S+ 0 0 50 1,-0.2 52,-0.0 2,-0.2 -2,-0.0 0.519 105.2 48.3 -78.1 -10.2 9.2 5.5 -0.7 58 90 A E H <4 S+ 0 0 120 -3,-2.3 -1,-0.2 1,-0.0 3,-0.1 0.642 115.2 45.3 -94.5 -26.5 11.2 8.0 1.3 59 91 A L H < S+ 0 0 46 -4,-1.4 2,-0.3 1,-0.2 -2,-0.2 0.873 118.8 24.2 -81.6 -45.4 11.2 5.8 4.4 60 92 A L < - 0 0 64 -4,-2.3 -1,-0.2 -5,-0.2 92,-0.0 -0.901 60.3-134.6-130.1 153.7 12.1 2.4 3.1 61 93 A S S S+ 0 0 130 -2,-0.3 -1,-0.1 1,-0.2 -4,-0.0 0.853 107.0 28.1 -70.5 -36.7 13.8 0.9 0.1 62 94 A N S S+ 0 0 88 -6,-0.1 -1,-0.2 -3,-0.0 2,-0.1 -0.513 75.9 174.0-128.4 63.4 11.1 -1.7 -0.4 63 95 A P - 0 0 7 0, 0.0 2,-0.4 0, 0.0 46,-0.3 -0.428 14.9-157.0 -71.5 149.3 7.7 -0.4 0.8 64 96 A Q B -e 153 0C 45 88,-3.0 90,-2.1 1,-0.2 91,-0.3 -0.975 21.3-151.2-129.3 139.7 4.7 -2.6 0.1 65 97 A F S S+ 0 0 5 -2,-0.4 90,-2.2 1,-0.3 2,-0.4 0.971 92.2 12.2 -68.7 -55.5 1.0 -1.8 -0.2 66 98 A I - 0 0 55 41,-0.2 2,-0.4 88,-0.1 -1,-0.3 -0.992 67.1-174.0-127.2 130.7 -0.1 -5.3 1.0 67 99 A V S S- 0 0 24 2,-0.4 83,-0.1 -2,-0.4 86,-0.1 -0.985 77.0 -12.9-121.6 123.9 2.2 -8.0 2.5 68 100 A D S S- 0 0 152 -2,-0.4 -1,-0.1 2,-0.1 3,-0.0 0.878 128.1 -53.6 53.9 40.5 0.8 -11.5 3.2 69 101 A G - 0 0 34 1,-0.1 2,-1.0 -3,-0.1 -2,-0.4 0.196 69.4 -74.6 81.6 158.5 -2.7 -10.2 2.7 70 102 A A S S+ 0 0 9 -4,-0.1 2,-0.2 23,-0.1 -1,-0.1 -0.829 73.9 157.5 -87.9 100.4 -4.7 -7.3 4.2 71 103 A T > - 0 0 51 -2,-1.0 3,-2.0 23,-0.0 4,-0.1 -0.772 57.1 -97.1-127.1 172.1 -5.5 -8.8 7.6 72 104 A R G > S+ 0 0 51 1,-0.3 3,-1.7 -2,-0.2 18,-0.1 0.748 115.3 66.7 -64.8 -25.9 -6.4 -7.7 11.1 73 105 A T G 3 S+ 0 0 59 1,-0.3 76,-1.5 17,-0.1 -1,-0.3 0.608 88.6 71.5 -68.2 -10.8 -2.7 -7.8 12.4 74 106 A D G < S+ 0 0 5 -3,-2.0 2,-0.8 74,-0.2 -1,-0.3 0.445 81.7 83.4 -81.6 -2.3 -2.1 -5.0 10.0 75 107 A I < + 0 0 0 -3,-1.7 2,-0.5 73,-0.1 73,-0.2 -0.831 49.8 156.5-112.0 93.4 -4.1 -2.7 12.3 76 108 A C B -F 147 0D 12 71,-2.1 71,-2.1 -2,-0.8 190,-0.2 -0.949 39.9-125.0-123.5 110.7 -2.0 -1.3 15.1 77 109 A Q - 0 0 17 188,-2.5 69,-0.1 -2,-0.5 2,-0.1 -0.168 25.5-165.3 -60.3 141.0 -3.2 1.9 16.6 78 110 A G - 0 0 18 2,-0.0 2,-1.8 4,-0.0 67,-0.3 -0.109 49.4 -47.1-103.2-151.8 -1.1 5.0 16.8 79 111 A A S S+ 0 0 70 65,-2.7 2,-0.3 -2,-0.1 66,-0.1 -0.463 101.5 88.1 -89.7 71.5 -1.3 8.3 18.7 80 112 A L S S- 0 0 12 -2,-1.8 2,-0.7 93,-0.1 3,-0.1 -0.973 81.0-113.5-162.4 152.3 -4.9 9.3 18.0 81 113 A G S S+ 0 0 11 -2,-0.3 94,-2.8 1,-0.2 3,-0.4 -0.112 78.3 113.0 -84.4 38.7 -8.4 8.6 19.5 82 114 A D > + 0 0 0 -2,-0.7 4,-2.4 92,-0.2 3,-0.3 -0.056 22.6 127.1-105.8 36.0 -9.6 6.6 16.5 83 115 A C H > S+ 0 0 0 1,-0.2 4,-3.0 2,-0.2 5,-0.2 0.887 73.2 58.4 -58.3 -38.2 -10.0 3.2 18.1 84 116 A W H > S+ 0 0 9 -3,-0.4 4,-1.5 240,-0.3 -1,-0.2 0.900 108.8 44.3 -57.7 -43.2 -13.6 3.0 16.8 85 117 A L H > S+ 0 0 0 -3,-0.3 4,-2.4 88,-0.2 -1,-0.2 0.942 114.6 47.8 -66.2 -48.0 -12.4 3.4 13.2 86 118 A L H X S+ 0 0 0 -4,-2.4 4,-2.8 2,-0.2 -2,-0.2 0.858 107.8 54.7 -66.6 -36.2 -9.5 0.9 13.6 87 119 A A H X S+ 0 0 0 -4,-3.0 4,-2.3 -5,-0.2 -1,-0.2 0.918 109.8 50.2 -59.0 -40.1 -11.8 -1.7 15.3 88 120 A A H X S+ 0 0 0 -4,-1.5 4,-2.5 -5,-0.2 -2,-0.2 0.908 109.8 48.6 -66.8 -45.8 -14.0 -1.4 12.2 89 121 A I H X S+ 0 0 0 -4,-2.4 4,-1.8 2,-0.2 -2,-0.2 0.943 110.3 51.3 -58.8 -46.3 -11.1 -1.8 9.8 90 122 A A H < S+ 0 0 0 -4,-2.8 4,-0.5 1,-0.2 3,-0.3 0.941 112.9 46.3 -56.0 -46.0 -9.9 -4.9 11.7 91 123 A S H >< S+ 0 0 3 -4,-2.3 3,-1.6 1,-0.2 -1,-0.2 0.904 106.0 59.9 -63.4 -40.7 -13.4 -6.4 11.4 92 124 A L H >< S+ 0 0 0 -4,-2.5 3,-2.1 1,-0.3 7,-0.4 0.862 93.8 65.0 -54.5 -41.1 -13.6 -5.5 7.7 93 125 A T T 3< S+ 0 0 17 -4,-1.8 -1,-0.3 -3,-0.3 -2,-0.2 0.720 88.6 68.6 -58.7 -21.1 -10.6 -7.6 6.9 94 126 A L T < S+ 0 0 72 -3,-1.6 2,-0.5 -4,-0.5 -1,-0.3 0.543 94.9 60.0 -75.8 -7.2 -12.5 -10.8 7.9 95 127 A N <> - 0 0 26 -3,-2.1 4,-2.7 -4,-0.2 -1,-0.2 -0.892 67.9-168.6-126.4 96.4 -14.8 -10.4 4.9 96 128 A E H > S+ 0 0 136 -2,-0.5 4,-2.4 1,-0.2 -1,-0.1 0.858 83.3 57.4 -54.8 -44.0 -12.8 -10.5 1.7 97 129 A T H 4 S+ 0 0 112 1,-0.2 4,-0.5 2,-0.2 -1,-0.2 0.944 115.5 33.3 -52.8 -56.2 -15.6 -9.3 -0.5 98 130 A I H >> S+ 0 0 19 1,-0.2 4,-1.9 2,-0.2 3,-0.7 0.844 113.1 62.5 -77.9 -27.8 -16.2 -6.0 1.4 99 131 A L H 3X S+ 0 0 6 -4,-2.7 4,-2.7 -7,-0.4 -1,-0.2 0.948 105.8 46.0 -57.0 -46.8 -12.6 -5.6 2.2 100 132 A H H 3< S+ 0 0 35 -4,-2.4 5,-0.3 1,-0.2 -1,-0.2 0.516 105.8 57.8 -86.7 -0.7 -11.7 -5.4 -1.4 101 133 A R H <4 S+ 0 0 99 -3,-0.7 -1,-0.2 -4,-0.5 -2,-0.2 0.854 114.2 39.7 -79.9 -42.1 -14.4 -2.9 -2.3 102 134 A V H < S+ 0 0 0 -4,-1.9 18,-2.0 1,-0.3 -2,-0.2 0.891 124.5 40.2 -71.2 -40.3 -13.0 -0.5 0.3 103 135 A V S < S- 0 0 0 -4,-2.7 -1,-0.3 -5,-0.2 16,-0.1 -0.845 92.6-142.6-112.0 89.8 -9.4 -1.3 -0.6 104 136 A P - 0 0 19 0, 0.0 3,-0.4 0, 0.0 14,-0.1 -0.207 19.0-110.4 -56.4 145.5 -9.2 -1.6 -4.5 105 137 A Y S S+ 0 0 156 -5,-0.3 -5,-0.0 1,-0.2 0, 0.0 -0.248 89.1 41.1 -68.6 156.4 -7.0 -4.2 -6.0 106 138 A G + 0 0 80 1,-0.2 2,-0.4 -2,-0.0 -1,-0.2 0.693 69.6 138.8 85.1 24.7 -3.9 -3.5 -8.0 107 139 A Q + 0 0 15 -3,-0.4 2,-0.3 -4,-0.1 -1,-0.2 -0.848 23.6 152.5-102.8 136.6 -2.2 -0.7 -6.0 108 140 A S - 0 0 37 -2,-0.4 -44,-0.1 3,-0.1 0, 0.0 -0.978 55.4-124.2-156.6 164.5 1.5 -0.7 -5.5 109 141 A F S S+ 0 0 17 -2,-0.3 3,-0.1 -46,-0.3 -45,-0.1 0.300 98.1 59.5 -91.5 6.3 4.8 1.1 -4.9 110 142 A Q S > S+ 0 0 96 1,-0.3 3,-2.2 2,-0.0 -2,-0.1 0.385 99.0 18.6-104.5-122.3 6.3 -0.5 -8.0 111 143 A E T 3 S+ 0 0 185 1,-0.3 -1,-0.3 0, 0.0 -3,-0.1 -0.267 132.4 10.7 -58.6 126.5 5.2 -0.3 -11.7 112 144 A G T 3 S+ 0 0 21 1,-0.3 -1,-0.3 -3,-0.1 2,-0.2 0.366 87.8 150.8 90.7 -4.3 2.8 2.7 -12.2 113 145 A Y < + 0 0 36 -3,-2.2 -1,-0.3 1,-0.1 -4,-0.1 -0.431 11.3 158.9 -61.3 130.2 3.5 4.3 -8.8 114 146 A A - 0 0 1 2,-0.3 -90,-3.0 -2,-0.2 -1,-0.1 -0.015 69.1 -89.1-141.5 27.9 3.1 8.1 -8.8 115 147 A G S S+ 0 0 0 -92,-0.2 19,-1.4 1,-0.2 2,-0.4 0.726 93.3 112.0 76.6 24.4 2.5 8.8 -5.1 116 148 A I E +B 133 0A 4 17,-0.2 -2,-0.3 18,-0.1 2,-0.3 -0.989 36.7 174.0-134.5 137.3 -1.3 8.4 -5.2 117 149 A F E -B 132 0A 1 15,-2.7 15,-2.1 -2,-0.4 2,-0.3 -0.856 11.8-153.5-131.3 166.5 -3.7 5.8 -3.7 118 150 A H E -B 131 0A 23 -2,-0.3 2,-0.3 13,-0.2 13,-0.2 -0.990 8.9-175.7-146.0 156.0 -7.5 5.4 -3.5 119 151 A F E -B 130 0A 0 11,-2.2 11,-3.1 -2,-0.3 2,-0.4 -0.926 22.7-124.7-144.7 159.5 -10.2 3.8 -1.4 120 152 A Q E +B 129 0A 34 -18,-2.0 2,-0.3 -2,-0.3 9,-0.2 -0.953 29.1 175.0-117.8 131.2 -14.0 3.5 -1.6 121 153 A L E -B 128 0A 0 7,-2.3 7,-3.1 -2,-0.4 2,-0.8 -0.917 37.5-116.5-129.6 155.2 -16.3 4.6 1.2 122 154 A W E +B 127 0A 85 62,-3.1 2,-0.3 -2,-0.3 5,-0.2 -0.871 58.0 152.0 -89.8 109.1 -20.1 4.8 1.7 123 155 A Q E > +B 126 0A 21 3,-3.2 3,-1.8 -2,-0.8 -2,-0.1 -0.999 52.6 4.5-148.1 144.5 -20.5 8.6 2.2 124 156 A F T 3 S- 0 0 144 -2,-0.3 3,-0.1 1,-0.3 -1,-0.1 0.786 129.2 -59.1 52.2 30.8 -23.1 11.3 1.6 125 157 A G T 3 S+ 0 0 51 1,-0.2 2,-0.3 -3,-0.0 -1,-0.3 0.720 122.6 92.1 69.5 24.2 -25.5 8.4 0.6 126 158 A E E < S- B 0 123A 96 -3,-1.8 -3,-3.2 -123,-0.0 2,-0.7 -0.957 83.2-112.2-139.1 151.3 -23.1 7.4 -2.2 127 159 A W E - B 0 122A 51 -2,-0.3 -124,-2.1 -5,-0.2 2,-0.4 -0.867 49.4-170.1 -78.3 119.5 -20.3 4.9 -2.8 128 160 A V E -aB 3 121A 6 -7,-3.1 -7,-2.3 -2,-0.7 2,-0.5 -0.904 23.9-136.8-120.4 138.9 -17.4 7.4 -3.3 129 161 A D E -aB 4 120A 13 -126,-2.4 -124,-2.7 -2,-0.4 2,-0.5 -0.881 24.2-164.8 -91.2 127.5 -13.8 6.9 -4.5 130 162 A V E - B 0 119A 0 -11,-3.1 -11,-2.2 -2,-0.5 2,-0.3 -0.964 1.7-156.2-118.7 124.0 -11.4 9.0 -2.3 131 163 A V E + B 0 118A 1 -2,-0.5 2,-0.3 -13,-0.2 -13,-0.2 -0.693 11.5 179.4 -93.4 153.4 -7.7 9.7 -3.4 132 164 A V E - B 0 117A 0 -15,-2.1 -15,-2.7 -2,-0.3 2,-0.2 -0.975 28.3-124.7-141.2 152.3 -4.8 10.5 -1.1 133 165 A D E - B 0 116A 0 -2,-0.3 -17,-0.2 -104,-0.3 -108,-0.1 -0.516 35.1-115.1 -80.0 165.3 -1.2 11.2 -1.8 134 166 A D S S+ 0 0 0 -19,-1.4 2,-0.4 -110,-0.3 -18,-0.1 0.271 72.0 127.3 -95.4 14.8 1.1 8.9 0.2 135 167 A L - 0 0 13 -20,-0.3 -80,-0.2 -80,-0.2 -2,-0.1 -0.572 42.8-170.3 -64.9 126.0 2.7 11.5 2.3 136 168 A L E -C 54 0B 2 -82,-2.4 -82,-2.4 -2,-0.4 2,-0.3 -0.920 29.0-101.3-125.8 146.2 2.2 10.3 5.9 137 169 A P E +C 53 0B 3 0, 0.0 7,-2.0 0, 0.0 8,-0.5 -0.481 52.4 170.4 -67.3 126.7 2.7 11.8 9.3 138 170 A T E -CD 52 143B 1 -86,-2.0 -86,-2.8 -2,-0.3 2,-0.3 -0.926 26.3-163.5-134.6 158.9 6.0 10.5 10.8 139 171 A K E > S- D 0 142B 107 3,-2.4 3,-1.8 -2,-0.3 -88,-0.1 -0.961 83.4 -7.7-142.4 128.2 8.3 11.2 13.7 140 172 A D T 3 S- 0 0 141 -2,-0.3 3,-0.1 -90,-0.3 -89,-0.1 0.873 131.0 -56.7 52.0 37.5 11.9 9.9 13.8 141 173 A G T 3 S+ 0 0 31 1,-0.2 2,-0.3 -89,-0.1 -1,-0.3 0.456 116.2 108.7 79.5 2.5 11.1 7.9 10.7 142 174 A K E < S-D 139 0B 155 -3,-1.8 -3,-2.4 1,-0.0 -1,-0.2 -0.863 77.2-100.9-113.2 145.2 8.1 6.0 12.2 143 175 A L E -D 138 0B 35 -2,-0.3 -5,-0.2 -5,-0.2 4,-0.1 -0.372 24.2-156.1 -58.4 136.0 4.4 6.4 11.5 144 176 A V S S+ 0 0 28 -7,-2.0 -65,-2.7 -66,-0.1 -1,-0.1 0.844 77.1 31.7 -81.0 -39.0 2.6 8.5 14.2 145 177 A F S S- 0 0 7 -8,-0.5 12,-0.1 -67,-0.3 -66,-0.1 0.312 116.7 -6.2 -99.2-138.2 -0.9 7.0 13.6 146 178 A V + 0 0 2 11,-0.1 2,-0.3 10,-0.1 -1,-0.3 -0.270 66.2 169.5 -64.4 145.4 -2.0 3.6 12.4 147 179 A H B -F 76 0D 71 -71,-2.1 -71,-2.1 -3,-0.1 2,-0.3 -0.959 31.2-109.6-146.2 162.9 0.7 1.1 11.3 148 180 A S - 0 0 7 5,-0.6 -74,-0.2 2,-0.4 5,-0.1 -0.665 22.4-125.5 -90.7 150.4 1.0 -2.6 10.4 149 181 A A S S+ 0 0 75 -76,-1.5 2,-0.9 -2,-0.3 -75,-0.1 0.751 108.3 74.8 -58.6 -25.6 2.8 -5.2 12.6 150 182 A Q S > S- 0 0 81 1,-0.1 3,-2.3 -77,-0.1 -2,-0.4 -0.839 85.0-151.8 -87.3 105.2 4.6 -5.7 9.2 151 183 A G T 3 S+ 0 0 64 -2,-0.9 -1,-0.1 1,-0.3 -2,-0.1 0.576 88.8 50.7 -64.4 -11.6 6.8 -2.6 9.3 152 184 A N T 3 S+ 0 0 34 -89,-0.1 -88,-3.0 -92,-0.0 2,-0.4 0.261 88.5 100.5-106.5 12.3 7.0 -2.3 5.5 153 185 A E B < +e 64 0C 2 -3,-2.3 -5,-0.6 -90,-0.2 -88,-0.2 -0.876 39.5 171.8-108.5 133.1 3.2 -2.5 4.8 154 186 A F > + 0 0 5 -90,-2.1 4,-2.5 -2,-0.4 5,-0.2 0.492 45.6 98.9-121.8 -6.6 1.2 0.6 4.2 155 187 A W H > S+ 0 0 0 -90,-2.2 4,-2.8 -91,-0.3 5,-0.2 0.908 90.9 47.3 -55.8 -43.1 -2.4 -0.1 3.1 156 188 A S H > S+ 0 0 0 -91,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.914 110.6 51.1 -69.5 -38.9 -3.9 0.5 6.5 157 189 A A H > S+ 0 0 2 2,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.923 113.9 46.6 -57.6 -41.7 -1.9 3.8 7.1 158 190 A L H X S+ 0 0 0 -4,-2.5 4,-2.4 2,-0.2 -2,-0.2 0.911 110.9 50.3 -71.2 -39.7 -3.3 4.9 3.7 159 191 A L H X S+ 0 0 0 -4,-2.8 4,-2.4 -5,-0.2 5,-0.2 0.924 110.2 50.3 -63.1 -48.0 -6.9 3.9 4.4 160 192 A E H X S+ 0 0 2 -4,-2.7 4,-2.6 1,-0.2 -1,-0.2 0.909 109.7 52.3 -55.8 -39.8 -6.8 5.7 7.8 161 193 A K H X S+ 0 0 0 -4,-1.9 4,-2.6 -5,-0.2 -2,-0.2 0.934 108.9 49.1 -63.8 -44.2 -5.5 8.8 5.9 162 194 A A H X S+ 0 0 0 -4,-2.4 4,-2.0 2,-0.2 -1,-0.2 0.884 111.6 49.5 -59.7 -40.2 -8.4 8.7 3.4 163 195 A Y H X S+ 0 0 0 -4,-2.4 4,-1.2 2,-0.2 -2,-0.2 0.915 110.1 50.5 -66.8 -40.4 -10.9 8.4 6.2 164 196 A A H >X>S+ 0 0 0 -4,-2.6 4,-0.7 -5,-0.2 5,-0.7 0.942 107.4 56.5 -56.7 -45.3 -9.3 11.4 7.9 165 197 A K H ><5S+ 0 0 7 -4,-2.6 3,-1.3 1,-0.3 -2,-0.2 0.916 104.8 48.5 -55.9 -50.4 -9.5 13.3 4.6 166 198 A V H 3<5S+ 0 0 16 -4,-2.0 -1,-0.3 1,-0.3 -2,-0.2 0.778 115.0 47.9 -63.5 -26.9 -13.3 12.8 4.3 167 199 A N H <<5S- 0 0 68 -4,-1.2 -1,-0.3 -3,-0.6 -2,-0.2 0.422 118.0-110.6 -93.4 -4.2 -13.7 14.0 7.9 168 200 A G T <<5S+ 0 0 47 -3,-1.3 2,-0.3 -4,-0.7 -3,-0.2 -0.076 80.9 2.9 107.0 -33.2 -11.5 17.0 7.6 169 201 A S S S+ 0 0 1 -135,-2.0 3,-2.2 -2,-0.3 4,-0.2 0.922 121.1 57.0 -59.2 -43.9 -6.9 13.3 11.7 171 203 A E G > S+ 0 0 14 -135,-2.5 3,-2.2 1,-0.3 -1,-0.2 0.850 93.7 68.1 -61.1 -31.8 -7.9 15.1 14.9 172 204 A A G 3 S+ 0 0 44 1,-0.3 -1,-0.3 -136,-0.2 -2,-0.2 0.709 94.3 60.5 -55.6 -21.8 -11.5 15.0 13.6 173 205 A L G < S+ 0 0 0 -3,-2.2 2,-0.6 -4,-0.3 -1,-0.3 0.493 74.8 112.2 -84.2 -6.9 -11.3 11.2 14.2 174 206 A S S < S+ 0 0 44 -3,-2.2 -92,-0.2 -4,-0.2 -3,-0.0 -0.595 80.6 10.9 -78.2 115.9 -10.6 11.4 17.9 175 207 A G S S+ 0 0 38 -94,-2.8 2,-0.3 -2,-0.6 -93,-0.1 0.651 86.4 138.4 85.1 114.4 -13.6 10.0 19.8 176 208 A G - 0 0 14 148,-2.2 2,-0.5 -95,-0.1 3,-0.1 -0.957 48.9 -82.2-169.7-172.5 -16.2 8.1 17.9 177 209 A C >> - 0 0 61 -2,-0.3 4,-1.3 1,-0.1 3,-1.2 -0.936 20.4-148.1-119.4 119.3 -18.7 5.4 17.2 178 210 A T H 3> S+ 0 0 3 -2,-0.5 4,-2.5 1,-0.3 3,-0.3 0.887 99.8 59.2 -49.8 -43.7 -17.7 2.0 15.8 179 211 A S H 3> S+ 0 0 17 1,-0.2 4,-2.5 2,-0.2 -1,-0.3 0.791 99.3 58.2 -57.8 -33.8 -21.1 1.6 14.0 180 212 A E H <> S+ 0 0 98 -3,-1.2 4,-2.3 2,-0.2 -1,-0.2 0.927 108.9 43.6 -62.3 -47.7 -20.4 4.9 12.1 181 213 A A H X S+ 0 0 0 -4,-1.3 4,-1.1 -3,-0.3 -2,-0.2 0.896 111.7 55.5 -63.2 -41.8 -17.2 3.4 10.6 182 214 A F H >< S+ 0 0 0 -4,-2.5 3,-0.7 1,-0.2 4,-0.5 0.947 111.0 44.1 -53.0 -51.1 -19.1 0.1 10.0 183 215 A E H >X S+ 0 0 63 -4,-2.5 4,-3.1 1,-0.2 3,-1.4 0.908 108.7 57.1 -60.9 -44.1 -21.7 2.0 8.0 184 216 A D H 3< S+ 0 0 23 -4,-2.3 -62,-3.1 1,-0.3 -1,-0.2 0.668 111.5 44.1 -64.5 -18.4 -19.1 4.0 6.1 185 217 A F T << S+ 0 0 0 -4,-1.1 -1,-0.3 -3,-0.7 -2,-0.2 0.468 132.3 13.9 -98.0 -7.0 -17.5 0.7 5.0 186 218 A T T <4 S- 0 0 18 -3,-1.4 -2,-0.2 -4,-0.5 -3,-0.2 0.610 77.5-129.1-141.1 -29.2 -20.7 -1.1 4.0 187 219 A G < + 0 0 35 -4,-3.1 -4,-0.1 -5,-0.2 -3,-0.1 0.704 68.0 141.8 68.4 19.1 -23.9 1.0 3.7 188 220 A G - 0 0 21 -6,-0.3 2,-0.5 -5,-0.2 133,-0.2 -0.097 58.5 -89.5 -84.8-175.0 -25.4 -1.7 5.9 189 221 A V E -G 320 0E 107 131,-2.0 131,-2.9 -3,-0.1 2,-0.4 -0.850 38.4-155.6-102.0 121.8 -27.8 -1.8 8.9 190 222 A T E +G 319 0E 41 -2,-0.5 2,-0.3 129,-0.2 129,-0.2 -0.791 15.5 172.2-103.4 144.3 -26.4 -1.4 12.4 191 223 A E E -G 318 0E 69 127,-2.4 127,-2.9 -2,-0.4 2,-0.3 -0.935 13.7-152.9-139.8 155.1 -27.9 -2.6 15.7 192 224 A W E -G 317 0E 150 -2,-0.3 2,-0.4 125,-0.2 125,-0.2 -0.924 3.8-146.6-130.5 161.2 -26.5 -2.7 19.2 193 225 A Y E -G 316 0E 38 123,-2.5 123,-1.8 -2,-0.3 2,-0.8 -0.987 15.0-134.3-131.0 135.2 -27.1 -4.9 22.3 194 226 A D E > -G 315 0E 63 -2,-0.4 3,-2.2 3,-0.2 121,-0.2 -0.814 19.2-156.0 -87.1 108.8 -27.0 -4.0 25.9 195 227 A L G > S+ 0 0 5 119,-2.4 3,-0.9 -2,-0.8 -1,-0.2 0.697 90.1 61.2 -68.7 -17.8 -25.0 -6.9 27.3 196 228 A Q G 3 S+ 0 0 102 118,-0.5 -1,-0.3 1,-0.3 119,-0.1 0.584 115.3 35.3 -81.7 -7.9 -26.5 -6.5 30.8 197 229 A K G < S+ 0 0 176 -3,-2.2 -1,-0.3 2,-0.0 -3,-0.2 -0.292 89.8 166.6-132.9 46.2 -29.9 -7.2 29.2 198 230 A A < - 0 0 34 -3,-0.9 -3,-0.1 -5,-0.1 -5,-0.0 -0.390 39.7-113.2 -70.4 135.4 -28.7 -9.7 26.6 199 231 A P > - 0 0 51 0, 0.0 3,-1.7 0, 0.0 4,-0.2 -0.327 28.7-114.6 -60.0 152.0 -31.3 -11.9 24.7 200 232 A S T 3 S+ 0 0 138 1,-0.3 3,-0.3 2,-0.1 4,-0.1 0.743 116.2 48.5 -62.7 -24.7 -31.1 -15.6 25.6 201 233 A D T >> S+ 0 0 84 1,-0.2 4,-2.1 2,-0.1 3,-0.5 0.179 73.6 118.1-101.3 17.2 -30.1 -16.4 22.0 202 234 A L H <> S+ 0 0 1 -3,-1.7 4,-2.5 1,-0.2 5,-0.2 0.871 72.4 55.3 -53.4 -43.2 -27.3 -13.7 21.7 203 235 A Y H 3> S+ 0 0 13 -3,-0.3 4,-2.5 1,-0.2 -1,-0.2 0.914 108.7 48.2 -58.5 -39.4 -24.5 -16.2 21.2 204 236 A Q H <> S+ 0 0 123 -3,-0.5 4,-2.4 2,-0.2 -1,-0.2 0.888 109.2 53.5 -67.8 -38.7 -26.5 -17.7 18.2 205 237 A I H X S+ 0 0 42 -4,-2.1 4,-2.3 2,-0.2 -2,-0.2 0.915 110.8 47.5 -56.6 -45.8 -27.0 -14.2 16.9 206 238 A I H X S+ 0 0 0 -4,-2.5 4,-2.7 2,-0.2 5,-0.2 0.923 110.8 50.3 -63.0 -48.0 -23.2 -13.6 17.1 207 239 A L H X S+ 0 0 43 -4,-2.5 4,-2.4 1,-0.2 -2,-0.2 0.928 112.4 47.7 -54.6 -47.6 -22.4 -17.0 15.4 208 240 A K H X S+ 0 0 133 -4,-2.4 4,-2.0 2,-0.2 -2,-0.2 0.903 112.1 48.7 -61.4 -46.9 -24.8 -16.2 12.5 209 241 A A H X>S+ 0 0 1 -4,-2.3 5,-2.4 2,-0.2 4,-1.0 0.929 112.0 48.3 -61.4 -47.3 -23.4 -12.7 12.0 210 242 A L H ><5S+ 0 0 36 -4,-2.7 3,-0.9 1,-0.2 -2,-0.2 0.934 109.8 54.2 -59.0 -44.7 -19.8 -13.9 12.0 211 243 A E H 3<5S+ 0 0 165 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.878 110.0 45.3 -56.3 -43.0 -20.8 -16.6 9.5 212 244 A R H 3<5S- 0 0 120 -4,-2.0 -1,-0.2 -5,-0.1 -2,-0.2 0.598 119.3-108.4 -82.0 -7.8 -22.4 -14.1 7.0 213 245 A G T <<5 + 0 0 14 -4,-1.0 -3,-0.2 -3,-0.9 -2,-0.1 0.636 61.8 158.9 89.0 16.7 -19.4 -11.7 7.3 214 246 A S < - 0 0 8 -5,-2.4 2,-0.4 -6,-0.2 106,-0.2 -0.208 44.1-108.7 -60.5 160.9 -21.2 -9.0 9.3 215 247 A L E -H 319 0E 1 104,-2.1 104,-2.7 -36,-0.0 2,-0.4 -0.855 36.3-172.5-101.6 133.9 -19.0 -6.6 11.3 216 248 A L E +H 318 0E 2 28,-0.5 28,-2.4 -2,-0.4 2,-0.3 -0.981 9.3 167.4-130.6 139.0 -19.0 -6.9 15.1 217 249 A G E -HI 317 243E 0 100,-2.2 100,-3.0 -2,-0.4 2,-0.3 -0.957 10.5-163.7-141.8 158.3 -17.4 -4.7 17.8 218 250 A C E -HI 316 242E 2 24,-2.3 24,-2.6 -2,-0.3 2,-0.3 -0.965 5.3-177.7-142.6 162.3 -17.7 -4.3 21.5 219 251 A S E -H 315 0E 18 96,-1.9 95,-2.4 -2,-0.3 96,-2.1 -0.979 24.7-126.0-152.8 164.1 -16.9 -1.9 24.4 220 252 A I - 0 0 11 17,-0.4 19,-3.4 20,-0.4 20,-0.3 -0.973 32.6-128.4-115.1 122.1 -17.0 -1.4 28.2 221 253 A N - 0 0 97 -2,-0.5 2,-1.0 17,-0.2 17,-0.0 -0.447 8.9-133.0 -69.0 137.7 -18.7 1.7 29.4 222 254 A I + 0 0 52 1,-0.2 -1,-0.1 -2,-0.1 8,-0.0 -0.841 34.1 173.6 -87.2 102.3 -16.9 3.9 31.8 223 255 A S S S+ 0 0 106 -2,-1.0 -1,-0.2 1,-0.1 -2,-0.0 0.769 71.0 39.8 -86.6 -31.0 -19.8 4.4 34.3 224 256 A D S S- 0 0 125 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.921 118.7 -96.9 -84.2 -50.9 -18.1 6.3 37.1 225 257 A I S S- 0 0 113 0, 0.0 -3,-0.1 0, 0.0 0, 0.0 -0.205 79.3 -45.9 163.7 -46.4 -15.9 8.6 34.9 226 258 A R S > S+ 0 0 176 4,-0.0 3,-1.4 0, 0.0 12,-0.1 0.177 94.8 132.1 176.3 12.8 -12.4 7.0 34.8 227 259 A D T 3 S+ 0 0 96 1,-0.3 2,-0.7 3,-0.1 3,-0.1 0.870 70.5 44.7 -53.9 -61.3 -12.1 6.1 38.5 228 260 A L T 3 S- 0 0 96 1,-0.2 -1,-0.3 2,-0.1 5,-0.0 0.027 127.2 -96.0 -74.3 32.6 -10.9 2.4 38.5 229 261 A E < - 0 0 130 -3,-1.4 -1,-0.2 -2,-0.7 9,-0.1 0.134 31.7 -85.8 73.5 167.5 -8.5 3.5 35.7 230 262 A A S S+ 0 0 51 -3,-0.1 8,-3.3 1,-0.1 2,-0.4 0.859 120.4 60.4 -65.2 -38.9 -8.9 3.4 31.9 231 263 A I B S-L 237 0F 64 6,-0.2 6,-0.2 1,-0.1 -1,-0.1 -0.795 86.8-136.1 -97.1 129.3 -7.5 -0.2 32.3 232 264 A T > - 0 0 18 4,-3.4 3,-1.7 -2,-0.4 -2,-0.1 -0.178 30.9 -96.9 -75.3 172.1 -9.4 -2.7 34.4 233 265 A F T 3 S+ 0 0 164 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.814 126.2 48.7 -59.2 -30.9 -8.0 -5.1 37.0 234 266 A K T 3 S- 0 0 103 2,-0.1 38,-1.9 37,-0.0 39,-0.3 0.135 125.5 -98.9 -98.9 19.1 -8.0 -7.9 34.3 235 267 A N S < S+ 0 0 44 -3,-1.7 2,-0.3 1,-0.3 -2,-0.1 0.745 75.5 140.0 74.0 25.9 -6.3 -5.8 31.7 236 268 A L - 0 0 0 34,-0.1 -4,-3.4 35,-0.0 2,-0.5 -0.756 49.5-128.4 -90.1 148.5 -9.3 -4.7 29.6 237 269 A V B > -L 231 0F 6 -2,-0.3 3,-0.6 -6,-0.2 -17,-0.4 -0.867 20.5-143.6 -99.6 124.6 -9.5 -1.1 28.4 238 270 A R T 3 S+ 0 0 42 -8,-3.3 -17,-0.2 -2,-0.5 3,-0.1 -0.500 79.9 20.9 -83.8 157.3 -12.7 0.8 29.1 239 271 A G T 3 S+ 0 0 26 -19,-3.4 2,-0.4 1,-0.2 -1,-0.2 0.799 102.6 122.1 58.1 33.1 -14.3 3.4 26.8 240 272 A H < - 0 0 0 -3,-0.6 2,-0.4 -20,-0.3 -20,-0.4 -0.980 64.9-119.1-136.2 133.1 -12.4 1.6 24.0 241 273 A A - 0 0 0 -2,-0.4 2,-0.3 -22,-0.1 -22,-0.2 -0.593 28.9-175.9 -78.2 122.7 -13.5 -0.1 20.8 242 274 A Y E -I 218 0E 0 -24,-2.6 -24,-2.3 -2,-0.4 2,-0.4 -0.875 22.5-127.5-108.0 150.5 -12.6 -3.8 20.3 243 275 A S E -IJ 217 263E 0 20,-2.1 20,-2.7 -2,-0.3 2,-0.6 -0.789 14.6-138.4 -90.0 136.7 -13.3 -6.0 17.2 244 276 A V E + J 0 262E 1 -28,-2.4 -28,-0.5 -2,-0.4 18,-0.3 -0.898 30.1 171.6 -93.7 121.4 -15.2 -9.2 17.7 245 277 A T E - 0 0 6 16,-2.5 2,-0.3 -2,-0.6 17,-0.2 0.483 50.3 -2.9-116.6 -7.3 -13.3 -11.7 15.5 246 278 A D E - J 0 261E 30 15,-1.4 15,-2.8 2,-0.0 2,-0.3 -0.975 42.4-152.0-172.0 165.7 -14.6 -15.2 16.2 247 279 A A E + J 0 260E 2 -2,-0.3 2,-0.3 13,-0.3 13,-0.2 -0.898 30.3 159.1-149.1 118.5 -16.9 -17.4 18.2 248 280 A K E - J 0 259E 91 11,-1.0 11,-2.8 -2,-0.3 2,-0.3 -0.951 30.7-129.5-142.1 157.9 -16.0 -21.0 18.8 249 281 A Q E - J 0 258E 81 -2,-0.3 2,-0.3 9,-0.2 9,-0.2 -0.852 20.5-167.2-113.8 144.3 -17.0 -23.8 21.3 250 282 A V E - J 0 257E 0 7,-2.7 7,-2.5 -2,-0.3 2,-0.8 -0.886 26.3-118.8-127.4 161.7 -14.5 -26.0 23.2 251 283 A T E - J 0 256E 59 -2,-0.3 2,-0.7 5,-0.2 35,-0.4 -0.865 31.8-172.6-102.0 102.5 -14.8 -29.2 25.3 252 284 A Y E > S- J 0 255E 60 3,-2.9 3,-1.2 -2,-0.8 33,-0.2 -0.870 73.3 -26.5-104.5 110.4 -13.7 -28.2 28.8 253 285 A Q T 3 S- 0 0 127 31,-2.5 -1,-0.2 -2,-0.7 32,-0.1 0.913 128.3 -47.6 45.6 52.6 -13.5 -31.3 31.0 254 286 A G T 3 S+ 0 0 74 -3,-0.3 2,-0.4 30,-0.3 -1,-0.2 0.538 122.0 100.3 73.6 9.5 -16.1 -33.1 28.9 255 287 A Q E < S-J 252 0E 114 -3,-1.2 -3,-2.9 2,-0.0 -1,-0.2 -0.987 75.6-113.1-127.2 134.4 -18.6 -30.2 28.8 256 288 A R E -J 251 0E 145 -2,-0.4 2,-0.4 -5,-0.2 -5,-0.2 -0.408 29.8-169.7 -64.9 139.1 -19.1 -27.6 26.0 257 289 A V E -J 250 0E 17 -7,-2.5 -7,-2.7 -2,-0.1 2,-0.5 -1.000 18.4-133.2-129.9 129.2 -18.1 -24.0 26.8 258 290 A N E -J 249 0E 40 -2,-0.4 48,-2.9 -9,-0.2 49,-0.4 -0.744 28.0-169.8 -83.7 125.6 -19.0 -21.2 24.4 259 291 A L E -JK 248 305E 0 -11,-2.8 -11,-1.0 -2,-0.5 2,-0.3 -0.784 12.0-160.6-114.8 156.9 -16.1 -18.9 23.6 260 292 A I E -JK 247 304E 0 44,-2.8 44,-2.3 -2,-0.3 2,-0.4 -0.990 9.4-148.8-134.9 143.9 -15.8 -15.5 21.9 261 293 A R E +JK 246 303E 37 -15,-2.8 -16,-2.5 -2,-0.3 -15,-1.4 -0.935 19.0 172.5-117.3 134.8 -12.6 -13.9 20.4 262 294 A M E -JK 244 302E 0 40,-2.5 40,-2.3 -2,-0.4 2,-0.4 -0.887 19.7-137.6-137.8 169.0 -11.9 -10.3 20.2 263 295 A R E -JK 243 301E 4 -20,-2.7 -20,-2.1 -2,-0.3 38,-0.3 -0.968 10.0-139.5-136.2 123.4 -9.0 -8.0 19.2 264 296 A N > - 0 0 0 36,-3.0 3,-2.8 -2,-0.4 4,-0.2 -0.659 21.8-137.7 -74.0 120.7 -7.7 -4.8 20.8 265 297 A P T 3 S+ 0 0 0 0, 0.0 -188,-2.5 0, 0.0 -1,-0.1 0.584 99.0 76.1 -62.2 -7.8 -6.8 -2.4 17.8 266 298 A W T 3 S- 0 0 56 2,-0.3 3,-0.1 -190,-0.2 34,-0.1 0.710 103.6-129.6 -64.9 -22.0 -3.6 -1.5 19.7 267 299 A G S < S+ 0 0 13 -3,-2.8 2,-0.3 1,-0.2 33,-0.3 0.650 84.0 51.0 75.3 15.4 -2.3 -4.9 18.5 268 300 A E + 0 0 104 31,-0.3 -2,-0.3 -4,-0.2 -1,-0.2 -0.953 66.2 73.6-166.8 171.6 -1.4 -5.5 22.2 269 301 A V - 0 0 25 -2,-0.3 2,-0.3 1,-0.1 -1,-0.2 0.955 59.7-175.3 72.2 95.1 -2.8 -5.3 25.8 270 302 A E - 0 0 3 1,-0.1 -1,-0.1 -34,-0.1 31,-0.1 -0.803 31.1 -81.7-124.7 153.5 -5.1 -8.3 26.4 271 303 A W - 0 0 3 -2,-0.3 6,-0.3 29,-0.1 -36,-0.2 -0.162 29.9-165.0 -38.2 134.9 -7.5 -9.9 28.9 272 304 A K + 0 0 109 -38,-1.9 -1,-0.1 4,-0.1 -37,-0.1 0.121 55.8 96.8-117.6 13.8 -5.7 -11.9 31.6 273 305 A G S > S- 0 0 8 -39,-0.3 3,-2.2 1,-0.2 6,-0.2 -0.076 88.8 -31.9 -87.4-167.5 -8.7 -13.8 32.9 274 306 A P T 3 S+ 0 0 46 0, 0.0 31,-0.4 0, 0.0 -1,-0.2 -0.209 131.7 18.0 -46.9 135.4 -10.0 -17.3 32.1 275 307 A W T 3 S+ 0 0 5 1,-0.3 28,-0.6 29,-0.1 29,-0.1 0.245 89.8 137.1 80.6 -7.4 -9.3 -18.3 28.5 276 308 A S S X S- 0 0 7 -3,-2.2 3,-1.9 26,-0.1 -1,-0.3 -0.152 76.2 -89.8 -59.6 165.0 -6.6 -15.6 28.0 277 309 A D T 3 S+ 0 0 14 -6,-0.3 -1,-0.1 1,-0.3 -5,-0.1 0.785 126.7 33.8 -51.9 -37.2 -3.5 -16.8 26.2 278 310 A N T 3 S+ 0 0 113 -5,-0.1 -1,-0.3 3,-0.0 -2,-0.1 0.234 91.5 124.8-104.1 6.1 -1.6 -17.9 29.4 279 311 A S X - 0 0 17 -3,-1.9 3,-0.6 -6,-0.2 4,-0.2 -0.268 67.2-124.0 -71.2 157.7 -4.7 -19.1 31.4 280 312 A Y G > S+ 0 0 189 1,-0.2 3,-1.5 2,-0.1 4,-0.3 0.675 95.6 83.6 -71.6 -21.4 -5.0 -22.6 32.9 281 313 A E G > S+ 0 0 41 1,-0.3 3,-1.8 2,-0.2 -1,-0.2 0.833 80.5 62.4 -55.9 -34.9 -8.3 -23.3 31.1 282 314 A W G X S+ 0 0 0 -3,-0.6 3,-1.1 1,-0.3 -1,-0.3 0.753 89.6 70.2 -64.3 -25.2 -6.5 -24.4 27.9 283 315 A N G < S+ 0 0 100 -3,-1.5 -1,-0.3 1,-0.2 -2,-0.2 0.672 100.4 48.7 -59.8 -19.5 -4.9 -27.3 29.8 284 316 A K G < S+ 0 0 108 -3,-1.8 -31,-2.5 -4,-0.3 -30,-0.3 0.144 92.7 86.7-119.0 16.6 -8.3 -29.0 30.1 285 317 A V S < S- 0 0 10 -3,-1.1 -33,-0.2 -33,-0.2 -35,-0.0 -0.571 95.2 -68.9-102.3 174.3 -9.7 -28.9 26.5 286 318 A D > - 0 0 75 -35,-0.4 4,-2.3 -2,-0.2 5,-0.2 -0.471 46.4-127.8 -58.7 130.6 -9.3 -31.3 23.6 287 319 A P H > S+ 0 0 73 0, 0.0 4,-2.2 0, 0.0 5,-0.1 0.855 110.2 51.9 -52.4 -40.2 -5.6 -31.0 22.5 288 320 A Y H > S+ 0 0 135 2,-0.2 4,-2.4 1,-0.2 5,-0.2 0.918 108.0 50.3 -60.0 -49.0 -6.8 -30.4 18.9 289 321 A E H > S+ 0 0 38 1,-0.2 4,-2.2 2,-0.2 5,-0.4 0.901 110.7 51.2 -54.7 -44.9 -9.2 -27.6 20.0 290 322 A R H X S+ 0 0 57 -4,-2.3 4,-2.0 1,-0.2 -2,-0.2 0.916 112.0 45.7 -58.5 -47.0 -6.3 -26.0 21.9 291 323 A E H < S+ 0 0 132 -4,-2.2 -2,-0.2 1,-0.2 -1,-0.2 0.846 115.9 46.0 -69.8 -33.6 -4.0 -26.2 18.8 292 324 A Q H < S+ 0 0 112 -4,-2.4 -1,-0.2 -5,-0.1 -2,-0.2 0.851 126.2 25.4 -73.8 -35.2 -6.7 -24.8 16.5 293 325 A L H < S+ 0 0 22 -4,-2.2 2,-0.3 -5,-0.2 -3,-0.2 0.863 101.0 76.2-103.8 -45.0 -7.8 -22.0 18.7 294 326 A R < - 0 0 65 -4,-2.0 2,-0.4 -5,-0.4 -18,-0.1 -0.571 48.1-178.2 -81.3 133.8 -5.2 -20.8 21.1 295 327 A V - 0 0 74 -2,-0.3 2,-1.5 2,-0.1 -18,-0.1 -0.968 20.0-147.2-128.8 112.8 -2.3 -18.6 19.9 296 328 A K + 0 0 130 -2,-0.4 2,-0.3 2,-0.1 -2,-0.0 -0.653 55.1 119.0 -80.4 87.5 0.2 -17.6 22.5 297 329 A M - 0 0 114 -2,-1.5 2,-1.4 4,-0.2 4,-0.2 -0.977 69.7-125.4-151.9 137.1 1.1 -14.2 21.2 298 330 A E + 0 0 109 -2,-0.3 -2,-0.1 1,-0.2 0, 0.0 -0.722 67.7 126.5 -80.5 90.4 1.0 -10.6 22.4 299 331 A D S S- 0 0 23 -2,-1.4 -31,-0.3 2,-0.3 -1,-0.2 0.260 82.9-103.7-133.6 5.7 -1.0 -9.5 19.4 300 332 A G S S+ 0 0 0 -33,-0.3 -36,-3.0 1,-0.2 2,-0.4 0.262 89.1 110.7 82.6 -9.3 -4.1 -7.8 21.0 301 333 A E E +K 263 0E 21 -38,-0.3 -2,-0.3 -4,-0.2 2,-0.3 -0.804 37.6 146.5-104.7 139.2 -6.3 -10.8 20.2 302 334 A F E -K 262 0E 2 -40,-2.3 -40,-2.5 -2,-0.4 2,-0.3 -0.988 37.5-110.9-160.6 165.2 -7.7 -13.2 22.8 303 335 A W E +K 261 0E 6 -28,-0.6 2,-0.3 -2,-0.3 -42,-0.2 -0.720 23.9 178.9 -99.9 151.3 -10.6 -15.5 23.9 304 336 A M E -K 260 0E 0 -44,-2.3 -44,-2.8 -2,-0.3 2,-0.2 -0.960 37.6-102.8-135.2 157.0 -13.1 -15.2 26.7 305 337 A S E > -K 259 0E 1 -31,-0.4 4,-2.9 -2,-0.3 -46,-0.3 -0.560 33.4-120.1 -68.4 150.9 -16.0 -17.4 27.7 306 338 A F H > S+ 0 0 28 -48,-2.9 4,-2.5 1,-0.2 5,-0.2 0.899 115.3 58.0 -58.1 -38.6 -19.3 -15.9 26.5 307 339 A R H > S+ 0 0 141 -49,-0.4 4,-0.8 1,-0.2 -1,-0.2 0.924 110.8 40.7 -56.2 -48.8 -20.3 -15.9 30.2 308 340 A D H > S+ 0 0 6 1,-0.2 4,-2.7 2,-0.2 3,-0.4 0.880 111.2 59.4 -69.5 -37.7 -17.3 -13.7 31.1 309 341 A F H X S+ 0 0 0 -4,-2.9 4,-2.5 1,-0.2 -2,-0.2 0.924 105.5 46.7 -54.4 -49.0 -17.8 -11.6 28.0 310 342 A I H < S+ 0 0 52 -4,-2.5 -1,-0.2 1,-0.2 -2,-0.2 0.709 114.8 48.3 -73.8 -16.0 -21.3 -10.5 28.9 311 343 A R H < S+ 0 0 133 -4,-0.8 -2,-0.2 -3,-0.4 -1,-0.2 0.893 119.0 36.3 -82.8 -43.9 -20.2 -9.7 32.4 312 344 A E H < S+ 0 0 46 -4,-2.7 -2,-0.2 -5,-0.1 -3,-0.2 0.897 113.0 58.3 -79.8 -45.9 -17.1 -7.6 31.5 313 345 A F < - 0 0 0 -4,-2.5 -93,-0.2 -5,-0.3 3,-0.1 -0.491 56.7-169.6 -85.1 159.7 -18.4 -5.9 28.4 314 346 A T + 0 0 30 -95,-2.4 -119,-2.4 1,-0.3 -118,-0.5 0.651 65.6 41.0-121.3 -26.6 -21.4 -3.7 28.2 315 347 A K E -GH 194 219E 76 -96,-2.1 -96,-1.9 -121,-0.2 2,-0.4 -0.984 51.5-172.7-134.7 136.3 -22.1 -3.0 24.5 316 348 A L E -GH 193 218E 0 -123,-1.8 -123,-2.5 -2,-0.4 2,-0.4 -0.997 9.9-163.7-124.3 132.9 -22.0 -5.1 21.3 317 349 A E E -GH 192 217E 11 -100,-3.0 -100,-2.2 -2,-0.4 2,-0.4 -0.956 5.4-174.1-117.4 135.4 -22.5 -3.5 17.9 318 350 A I E -GH 191 216E 0 -127,-2.9 -127,-2.4 -2,-0.4 2,-0.6 -0.999 9.7-162.5-131.1 128.4 -23.3 -5.5 14.7 319 351 A C E -GH 190 215E 0 -104,-2.7 -104,-2.1 -2,-0.4 2,-0.4 -0.962 14.7-157.3-108.8 115.9 -23.5 -4.2 11.2 320 352 A N E -G 189 0E 26 -131,-2.9 -131,-2.0 -2,-0.6 2,-0.1 -0.789 9.0-169.2 -97.1 133.7 -25.4 -6.5 8.8 321 353 A L 0 0 50 -2,-0.4 -107,-0.1 -133,-0.2 -134,-0.1 -0.184 360.0 360.0 -98.3-164.9 -24.9 -6.5 5.0 322 354 A T 0 0 193 -2,-0.1 -1,-0.2 -134,-0.0 -134,-0.0 0.830 360.0 360.0 -85.6 360.0 -26.7 -8.0 2.0 323 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 324 367 A X 0 0 155 0, 0.0 -148,-2.2 0, 0.0 -240,-0.3 0.000 360.0 360.0 360.0 360.0 -15.0 5.5 22.1