==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSCRIPTION 09-OCT-07 2RHY . COMPND 2 MOLECULE: LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR H.LI,D.J.PATEL . 316 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 16584.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 183 57.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 13 4.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 68 21.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 17 5.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 44 13.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 29 9.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 3 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 3 1 2 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 205 A S 0 0 174 0, 0.0 2,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 157.7 24.1 15.1 31.5 2 206 A W - 0 0 91 308,-0.1 2,-0.4 1,-0.1 3,-0.1 -0.423 360.0-148.8 -64.2 139.4 24.1 13.8 35.0 3 207 A S > - 0 0 44 1,-0.2 4,-2.3 -2,-0.1 5,-0.1 -0.947 22.6-155.5-121.3 131.5 23.3 16.6 37.4 4 208 A W H > S+ 0 0 34 -2,-0.4 4,-2.8 2,-0.2 5,-0.2 0.932 102.1 54.1 -62.7 -44.1 24.4 17.1 41.0 5 209 A E H > S+ 0 0 148 1,-0.2 4,-1.8 2,-0.2 -1,-0.2 0.928 110.4 44.3 -54.8 -51.0 21.3 19.2 41.6 6 210 A S H > S+ 0 0 74 1,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.898 112.9 53.5 -62.5 -40.0 19.0 16.4 40.4 7 211 A Y H X S+ 0 0 17 -4,-2.3 4,-2.9 1,-0.2 5,-0.2 0.920 106.8 49.5 -62.4 -46.6 21.0 13.8 42.4 8 212 A L H X>S+ 0 0 35 -4,-2.8 5,-1.9 2,-0.2 4,-1.4 0.894 112.3 49.3 -60.6 -39.9 20.7 15.7 45.7 9 213 A E H <5S+ 0 0 126 -4,-1.8 3,-0.4 -5,-0.2 -2,-0.2 0.965 113.0 46.4 -62.6 -52.3 17.0 16.0 45.1 10 214 A E H <5S+ 0 0 131 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.895 122.4 36.0 -56.2 -44.2 16.6 12.3 44.4 11 215 A Q H <5S- 0 0 88 -4,-2.9 -1,-0.2 -5,-0.2 -2,-0.2 0.539 100.7-129.5 -89.1 -8.1 18.7 11.3 47.4 12 216 A K T <5 + 0 0 172 -4,-1.4 2,-0.2 -3,-0.4 -3,-0.2 0.968 63.6 142.3 55.3 51.0 17.5 14.1 49.7 13 217 A A < - 0 0 24 -5,-1.9 2,-0.3 -6,-0.1 -1,-0.2 -0.703 46.2-138.7-120.9 172.9 21.2 14.8 50.3 14 218 A I - 0 0 107 234,-0.4 236,-2.0 -2,-0.2 2,-0.2 -0.902 18.0-124.8-128.9 156.1 23.6 17.7 50.8 15 219 A T B -a 250 0A 48 -2,-0.3 236,-0.2 234,-0.3 234,-0.1 -0.567 34.7 -97.6 -96.5 162.8 27.1 18.4 49.5 16 220 A A - 0 0 2 234,-2.8 284,-0.4 -2,-0.2 229,-0.1 -0.722 51.8-112.2 -78.9 123.3 30.2 19.2 51.6 17 221 A P > - 0 0 57 0, 0.0 3,-1.7 0, 0.0 4,-0.3 -0.204 15.9-120.2 -57.1 148.6 30.4 23.0 51.6 18 222 A V G > S+ 0 0 87 1,-0.3 3,-2.1 2,-0.2 8,-0.1 0.840 109.8 70.3 -57.0 -34.5 33.4 24.6 49.8 19 223 A S G 3 S+ 0 0 104 1,-0.3 -1,-0.3 7,-0.0 4,-0.1 0.709 88.6 63.1 -58.8 -20.9 34.4 26.2 53.1 20 224 A L G < S+ 0 0 37 -3,-1.7 -1,-0.3 224,-0.1 2,-0.2 0.630 95.1 75.7 -80.4 -12.0 35.4 22.7 54.4 21 225 A F S < S- 0 0 11 -3,-2.1 2,-0.1 -4,-0.3 272,-0.1 -0.625 90.1-105.6 -98.8 157.6 38.1 22.3 51.7 22 226 A Q >> - 0 0 102 270,-0.3 4,-1.6 -2,-0.2 3,-1.0 -0.483 38.1-112.4 -73.0 152.0 41.5 24.0 51.5 23 227 A D H 3> S+ 0 0 145 1,-0.2 4,-2.6 2,-0.2 3,-0.1 0.883 117.9 57.9 -55.4 -36.5 41.5 26.7 48.8 24 228 A S H 34 S+ 0 0 71 1,-0.2 -1,-0.2 2,-0.2 58,-0.1 0.806 106.4 47.5 -65.3 -29.2 43.9 24.5 46.7 25 229 A Q H <4 S+ 0 0 2 -3,-1.0 -1,-0.2 1,-0.1 -2,-0.2 0.790 119.3 40.8 -79.3 -28.2 41.4 21.6 46.7 26 230 A A H < S+ 0 0 17 -4,-1.6 -2,-0.2 272,-0.1 -3,-0.1 0.753 81.3 112.9 -93.7 -27.0 38.5 24.0 45.8 27 231 A V < + 0 0 29 -4,-2.6 -5,-0.0 -5,-0.2 -4,-0.0 -0.245 26.5 161.1 -56.7 126.0 39.9 26.4 43.2 28 232 A T + 0 0 36 1,-0.0 -1,-0.1 -2,-0.0 -4,-0.0 0.516 55.5 76.2-121.6 -11.6 38.4 26.0 39.7 29 233 A H + 0 0 161 2,-0.1 2,-0.3 277,-0.0 -2,-0.1 0.507 68.1 104.3 -84.9 -1.6 39.1 29.2 37.9 30 234 A N S S- 0 0 68 1,-0.1 2,-0.2 32,-0.0 51,-0.1 -0.608 70.6-125.7 -81.6 138.2 42.8 28.6 37.1 31 235 A K - 0 0 145 -2,-0.3 2,-0.9 1,-0.1 -2,-0.1 -0.551 14.5-129.3 -80.6 143.4 43.7 27.6 33.5 32 236 A N + 0 0 21 -2,-0.2 31,-0.1 1,-0.1 29,-0.1 -0.836 28.8 177.5 -94.5 104.6 45.7 24.4 33.0 33 237 A G + 0 0 10 -2,-0.9 -1,-0.1 95,-0.1 2,-0.1 0.490 39.1 116.1 -87.1 -2.8 48.5 25.5 30.8 34 238 A F - 0 0 2 94,-0.1 2,-0.3 90,-0.1 -2,-0.1 -0.419 48.6-160.4 -69.0 139.1 50.3 22.2 30.6 35 239 A K > - 0 0 125 -2,-0.1 3,-2.4 1,-0.0 21,-0.3 -0.923 29.9 -85.6-126.0 150.7 50.5 20.5 27.2 36 240 A L T 3 S+ 0 0 130 -2,-0.3 21,-0.2 1,-0.3 -1,-0.0 -0.187 114.6 17.2 -46.9 127.6 51.1 17.0 26.0 37 241 A G T 3 S+ 0 0 34 19,-3.0 85,-0.3 1,-0.3 -1,-0.3 0.203 84.6 137.4 93.2 -18.9 54.8 16.5 25.7 38 242 A M < - 0 0 29 -3,-2.4 18,-2.6 83,-0.1 2,-0.3 -0.350 44.5-139.4 -62.6 145.4 56.1 19.4 27.9 39 243 A K E +Gh 55 123B 19 83,-2.0 85,-2.7 16,-0.2 50,-0.4 -0.800 31.4 147.8-110.5 151.6 58.9 18.3 30.2 40 244 A L E -G 54 0B 0 14,-2.7 14,-3.0 -2,-0.3 2,-0.3 -0.873 41.1 -91.8-159.0-171.0 59.6 19.3 33.8 41 245 A E E +GI 53 87B 0 46,-3.0 46,-3.4 -2,-0.3 2,-0.3 -0.889 44.1 153.1-118.5 148.5 61.0 18.2 37.1 42 246 A G E -GI 52 86B 0 10,-1.6 10,-2.8 -2,-0.3 44,-0.2 -0.988 41.7 -93.6-167.7 160.4 59.1 16.5 40.0 43 247 A I E -G 51 0B 14 42,-2.0 8,-0.2 -2,-0.3 6,-0.1 -0.476 39.3-113.7 -80.8 156.2 59.5 14.2 42.9 44 248 A D E > -G 47 0B 16 6,-1.8 3,-1.2 3,-0.9 6,-0.3 -0.791 18.9-145.3 -86.4 118.3 58.9 10.4 42.6 45 249 A P T 3 S+ 0 0 76 0, 0.0 -1,-0.2 0, 0.0 -2,-0.0 0.785 102.9 49.9 -56.0 -24.0 55.7 9.7 44.7 46 250 A Q T 3 S+ 0 0 122 1,-0.3 -2,-0.0 2,-0.0 -3,-0.0 0.697 125.0 26.9 -85.8 -23.4 57.4 6.4 45.6 47 251 A H E X S-G 44 0B 48 -3,-1.2 3,-2.6 3,-0.2 -3,-0.9 -0.622 74.5-177.4-139.8 74.6 60.7 8.0 46.6 48 252 A P E 3 S+ 0 0 9 0, 0.0 133,-0.1 0, 0.0 -1,-0.1 0.482 78.1 61.8 -52.8 -11.0 59.6 11.6 47.7 49 253 A S E 3 S+ 0 0 44 -5,-0.1 2,-0.3 131,-0.1 132,-0.0 0.551 94.7 81.0 -93.4 -9.6 63.2 12.7 48.4 50 254 A M E < - 0 0 53 -3,-2.6 -6,-1.8 -6,-0.3 2,-0.4 -0.787 64.7-150.1-106.0 143.9 64.2 12.1 44.7 51 255 A Y E -Gj 43 99B 4 47,-0.7 49,-2.9 -2,-0.3 2,-0.3 -0.886 17.7-178.1-111.9 137.7 63.6 14.3 41.6 52 256 A F E -Gj 42 100B 26 -10,-2.8 -10,-1.6 -2,-0.4 2,-0.5 -0.870 34.7-100.9-132.3 163.7 63.2 13.1 38.1 53 257 A I E -G 41 0B 3 47,-0.6 16,-1.4 -2,-0.3 2,-0.3 -0.722 48.0-171.2 -82.7 127.7 62.7 14.4 34.5 54 258 A L E -GK 40 68B 0 -14,-3.0 -14,-2.7 -2,-0.5 2,-0.4 -0.932 16.2-154.7-127.3 150.2 59.0 14.1 33.7 55 259 A T E -GK 39 67B 20 12,-2.1 12,-2.5 -2,-0.3 2,-0.6 -0.951 28.6-114.1-122.4 141.0 56.9 14.5 30.6 56 260 A V E + K 0 66B 1 -18,-2.6 -19,-3.0 -2,-0.4 10,-0.2 -0.636 36.8 174.3 -72.8 115.6 53.2 15.4 30.4 57 261 A A E + 0 0 29 8,-3.3 2,-0.3 -2,-0.6 -1,-0.2 0.675 63.7 7.4 -96.9 -22.7 51.6 12.3 29.0 58 262 A E E - K 0 65B 71 7,-1.2 7,-2.6 -23,-0.1 2,-0.4 -0.980 57.8-153.7-159.4 146.6 48.0 13.3 29.2 59 263 A V E + K 0 64B 57 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.990 18.6 166.3-125.6 133.0 45.9 16.4 30.1 60 264 A C E > - K 0 63B 27 3,-2.2 3,-2.1 -2,-0.4 248,-0.1 -0.861 60.8 -52.8-149.0 110.3 42.4 16.3 31.5 61 265 A G T 3 S- 0 0 22 246,-0.5 246,-0.1 -2,-0.3 -1,-0.1 -0.376 120.3 -18.9 61.2-134.1 40.7 19.2 33.0 62 266 A Y T 3 S+ 0 0 16 -3,-0.1 19,-3.1 241,-0.1 20,-0.3 0.162 127.0 82.1 -91.4 18.0 42.8 20.8 35.7 63 267 A R E < -KL 60 80B 1 -3,-2.1 -3,-2.2 17,-0.3 2,-0.3 -0.767 56.5-164.7-120.3 166.4 44.9 17.5 36.0 64 268 A L E -KL 59 79B 0 15,-2.5 15,-2.4 -2,-0.3 2,-0.5 -0.995 18.5-131.1-150.0 149.8 47.7 15.9 34.1 65 269 A R E -KL 58 78B 61 -7,-2.6 -8,-3.3 -2,-0.3 -7,-1.2 -0.904 26.6-152.0-103.4 126.2 49.4 12.5 33.9 66 270 A L E -KL 56 77B 0 11,-3.7 11,-2.0 -2,-0.5 2,-0.4 -0.806 4.9-157.6-104.1 142.1 53.1 12.5 34.2 67 271 A H E -K 55 0B 44 -12,-2.5 -12,-2.1 -2,-0.4 2,-0.8 -0.938 20.4-125.4-118.8 133.1 55.6 10.0 32.7 68 272 A F E > -K 54 0B 9 -2,-0.4 3,-2.8 4,-0.3 -14,-0.2 -0.718 39.8-114.5 -78.4 107.7 59.1 9.2 34.0 69 273 A D T 3 S+ 0 0 7 -16,-1.4 34,-1.4 -2,-0.8 -16,-0.1 -0.095 95.4 5.9 -45.2 127.8 61.3 9.7 30.9 70 274 A G T 3 S+ 0 0 47 1,-0.3 -1,-0.3 32,-0.2 2,-0.1 0.246 112.4 102.6 81.9 -13.2 62.9 6.5 29.8 71 275 A Y S < S- 0 0 84 -3,-2.8 -1,-0.3 1,-0.1 -3,-0.0 -0.460 80.7 -71.8-102.6 173.8 61.0 4.4 32.3 72 276 A S > - 0 0 42 1,-0.1 3,-1.6 -2,-0.1 -4,-0.3 -0.275 33.1-130.1 -61.1 143.5 57.9 2.0 32.2 73 277 A E G > S+ 0 0 147 1,-0.3 3,-2.0 2,-0.2 -1,-0.1 0.673 102.7 80.4 -66.5 -17.1 54.5 3.6 31.7 74 278 A X G 3 S+ 0 0 285 1,-0.3 -1,-0.3 -7,-0.0 -2,-0.1 0.710 87.2 57.5 -64.8 -15.8 53.5 1.5 34.7 75 279 A H G < S+ 0 0 85 -3,-1.6 -1,-0.3 -7,-0.1 -2,-0.2 0.508 79.9 124.7 -88.6 -9.2 55.1 4.3 36.8 76 280 A D < - 0 0 32 -3,-2.0 2,-0.3 -4,-0.1 -9,-0.2 -0.162 38.1-177.8 -53.7 148.1 52.9 7.0 35.4 77 281 A F E -L 66 0B 35 -11,-2.0 -11,-3.7 182,-0.0 2,-0.3 -0.991 21.3-121.4-149.8 158.0 50.9 9.1 37.8 78 282 A W E +L 65 0B 30 -2,-0.3 2,-0.3 -13,-0.3 -13,-0.2 -0.802 27.4 168.7-105.0 142.9 48.4 12.0 38.0 79 283 A V E -L 64 0B 18 -15,-2.4 -15,-2.5 -2,-0.3 2,-0.2 -0.911 36.0-106.0-140.7 165.8 48.6 15.4 39.7 80 284 A N E > -L 63 0B 6 -2,-0.3 3,-1.9 -17,-0.2 -17,-0.3 -0.628 35.9-112.4 -89.4 156.3 46.6 18.6 39.7 81 285 A A T 3 S+ 0 0 6 -19,-3.1 49,-0.3 1,-0.3 -18,-0.1 0.724 118.0 56.8 -63.0 -19.8 48.1 21.6 37.8 82 286 A N T 3 S+ 0 0 24 -20,-0.3 -1,-0.3 -58,-0.1 -19,-0.1 0.134 77.8 141.6 -97.4 22.0 48.5 23.4 41.1 83 287 A S X - 0 0 9 -3,-1.9 3,-0.6 1,-0.1 47,-0.4 -0.358 45.4-154.0 -62.9 137.7 50.7 20.6 42.5 84 288 A P T 3 S+ 0 0 40 0, 0.0 -1,-0.1 0, 0.0 -3,-0.0 0.441 86.3 76.3 -91.1 0.4 53.6 21.8 44.7 85 289 A D T 3 S+ 0 0 48 -43,-0.1 -42,-2.0 -42,-0.0 2,-0.3 0.301 85.5 66.9 -94.9 8.2 55.4 18.5 43.9 86 290 A I E < -I 42 0B 3 -3,-0.6 45,-0.4 -44,-0.2 -44,-0.3 -0.891 61.7-174.0-124.9 156.1 56.4 19.5 40.3 87 291 A H E -I 41 0B 2 -46,-3.4 -46,-3.0 -2,-0.3 45,-0.1 -0.976 29.6 -90.6-147.8 160.6 58.9 22.2 39.2 88 292 A P > - 0 0 7 0, 0.0 3,-2.3 0, 0.0 4,-0.2 -0.356 56.7 -84.0 -73.2 150.9 60.2 23.9 36.0 89 293 A A T 3 S+ 0 0 23 35,-0.4 37,-0.1 -50,-0.4 34,-0.0 -0.250 120.2 32.1 -52.6 135.9 63.2 22.6 34.2 90 294 A G T 3> S+ 0 0 18 -3,-0.1 4,-1.9 -50,-0.0 -1,-0.3 0.275 85.1 113.2 96.9 -10.0 66.3 24.1 35.8 91 295 A W H <> S+ 0 0 8 -3,-2.3 4,-1.5 1,-0.2 6,-0.2 0.910 71.8 54.0 -61.6 -45.9 64.7 24.2 39.3 92 296 A F H >>S+ 0 0 35 -4,-0.2 5,-2.0 1,-0.2 4,-0.6 0.872 110.1 49.2 -57.2 -38.5 67.0 21.5 40.8 93 297 A E H >45S+ 0 0 148 1,-0.2 3,-0.6 2,-0.2 -1,-0.2 0.903 111.2 47.5 -68.7 -43.3 70.0 23.5 39.7 94 298 A K H 3<5S+ 0 0 135 -4,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.666 119.4 39.8 -73.9 -17.0 68.8 26.8 41.1 95 299 A T H 3<5S- 0 0 40 -4,-1.5 -1,-0.2 -5,-0.2 -2,-0.2 0.338 110.9-109.7-115.5 5.1 67.8 25.3 44.5 96 300 A G T <<5 + 0 0 73 -4,-0.6 2,-0.2 -3,-0.6 -3,-0.2 0.682 69.2 138.1 77.7 19.0 70.7 22.9 45.1 97 301 A H < - 0 0 35 -5,-2.0 2,-0.4 -6,-0.2 -1,-0.2 -0.587 52.6-115.2 -96.1 162.2 68.8 19.6 44.6 98 302 A K - 0 0 122 -2,-0.2 -47,-0.7 -5,-0.0 2,-0.5 -0.763 22.5-149.2 -97.2 139.3 70.0 16.5 42.8 99 303 A L E -j 51 0B 5 -2,-0.4 -47,-0.2 -49,-0.1 -49,-0.0 -0.931 8.5-139.5-114.2 123.4 68.3 15.3 39.6 100 304 A Q E -j 52 0B 45 -49,-2.9 -47,-0.6 -2,-0.5 3,-0.1 -0.626 31.1-126.9 -75.1 130.9 68.1 11.7 38.6 101 305 A P - 0 0 19 0, 0.0 3,-0.1 0, 0.0 6,-0.1 -0.301 29.7 -85.1 -77.6 164.7 68.7 11.5 34.9 102 306 A P > - 0 0 5 0, 0.0 3,-1.9 0, 0.0 -32,-0.2 -0.219 63.1 -78.3 -62.1 159.7 66.4 9.7 32.4 103 307 A K T 3 S+ 0 0 134 -34,-1.4 3,-0.1 1,-0.3 -32,-0.0 -0.393 124.4 34.2 -59.4 134.2 67.0 6.0 31.9 104 308 A G T 3 S+ 0 0 75 1,-0.3 2,-0.3 -3,-0.1 -1,-0.3 0.383 100.6 101.9 100.0 -3.3 70.0 5.7 29.7 105 309 A Y < - 0 0 80 -3,-1.9 2,-0.3 -4,-0.1 -1,-0.3 -0.882 61.6-141.8-119.3 148.8 71.8 8.7 31.0 106 310 A K > - 0 0 142 -2,-0.3 3,-1.1 -3,-0.1 4,-0.0 -0.754 37.8-111.8 -96.5 150.6 74.7 9.3 33.4 107 311 A E G > S+ 0 0 82 -2,-0.3 3,-0.8 1,-0.3 -1,-0.1 0.781 116.6 50.3 -57.9 -29.7 74.1 12.4 35.5 108 312 A E G 3 S+ 0 0 167 1,-0.2 -1,-0.3 -7,-0.0 -3,-0.0 0.694 98.9 65.8 -81.6 -19.2 76.9 14.4 33.9 109 313 A E G < S+ 0 0 112 -3,-1.1 2,-0.5 5,-0.0 -1,-0.2 0.320 89.6 99.6 -81.2 9.4 75.6 13.6 30.4 110 314 A F < + 0 0 27 -3,-0.8 2,-0.3 -5,-0.1 3,-0.1 -0.876 32.9 141.8-110.6 128.9 72.6 15.6 31.5 111 315 A S > - 0 0 51 -2,-0.5 4,-2.4 1,-0.1 5,-0.2 -0.950 48.1-130.3-151.5 134.9 71.9 19.2 30.6 112 316 A W H > S+ 0 0 30 -2,-0.3 4,-2.9 1,-0.2 5,-0.3 0.872 105.4 57.9 -58.8 -37.3 68.4 20.4 29.8 113 317 A S H > S+ 0 0 76 2,-0.2 4,-1.7 1,-0.2 -1,-0.2 0.947 111.0 39.3 -60.9 -50.6 69.5 22.1 26.6 114 318 A Q H > S+ 0 0 85 1,-0.2 4,-3.0 2,-0.2 5,-0.2 0.953 116.6 52.2 -64.9 -45.7 71.0 19.0 25.0 115 319 A Y H X S+ 0 0 16 -4,-2.4 4,-1.6 1,-0.2 -2,-0.2 0.917 109.4 47.8 -55.0 -48.9 68.1 16.9 26.3 116 320 A L H X>S+ 0 0 40 -4,-2.9 5,-1.9 1,-0.2 4,-0.5 0.869 113.5 48.9 -62.5 -36.0 65.4 19.2 24.9 117 321 A R H ><5S+ 0 0 153 -4,-1.7 3,-0.6 -5,-0.3 -2,-0.2 0.936 111.1 49.8 -68.4 -45.2 67.2 19.3 21.6 118 322 A S H 3<5S+ 0 0 52 -4,-3.0 -2,-0.2 1,-0.3 -1,-0.2 0.744 120.6 35.2 -66.2 -22.4 67.6 15.5 21.5 119 323 A T H 3<5S- 0 0 43 -4,-1.6 -1,-0.3 -5,-0.2 -2,-0.2 0.375 101.8-133.0-111.4 1.1 63.9 14.9 22.2 120 324 A R T <<5 + 0 0 210 -3,-0.6 2,-0.2 -4,-0.5 -3,-0.2 0.896 60.4 139.3 46.4 46.6 62.8 18.0 20.2 121 325 A A < - 0 0 22 -5,-1.9 2,-0.4 -6,-0.2 -1,-0.2 -0.643 51.8-125.3-116.3 173.5 60.7 18.9 23.2 122 326 A Q - 0 0 154 -85,-0.3 -83,-2.0 -2,-0.2 2,-0.3 -0.945 22.4-125.0-119.5 139.1 59.7 22.1 25.1 123 327 A A B -h 39 0B 32 -2,-0.4 -83,-0.2 -85,-0.2 -85,-0.1 -0.641 39.0-101.0 -81.8 139.0 60.1 22.6 28.9 124 328 A A - 0 0 4 -85,-2.7 -35,-0.4 -2,-0.3 -1,-0.1 -0.391 51.1 -98.7 -59.1 133.6 56.8 23.5 30.6 125 329 A P > - 0 0 49 0, 0.0 3,-1.4 0, 0.0 4,-0.2 -0.169 23.1-122.1 -56.7 146.8 56.9 27.3 31.2 126 330 A K G > S+ 0 0 132 1,-0.3 3,-1.9 2,-0.2 -2,-0.1 0.841 104.5 67.2 -57.5 -40.7 57.9 28.7 34.6 127 331 A H G 3 S+ 0 0 147 1,-0.3 -1,-0.3 3,-0.0 -3,-0.0 0.619 89.0 67.2 -61.9 -11.2 54.7 30.6 35.2 128 332 A L G < S+ 0 0 24 -3,-1.4 2,-0.5 -95,-0.1 -1,-0.3 0.591 84.3 89.9 -84.7 -9.8 52.7 27.4 35.4 129 333 A F < - 0 0 11 -3,-1.9 -47,-0.1 -4,-0.2 3,-0.1 -0.775 52.9-167.3 -99.2 126.6 54.3 26.3 38.7 130 334 A V S S+ 0 0 88 -2,-0.5 2,-0.6 -47,-0.4 -1,-0.1 0.760 84.9 56.2 -75.2 -24.1 53.1 27.2 42.2 131 335 A S + 0 0 4 -48,-0.4 -1,-0.2 -45,-0.4 -48,-0.0 -0.930 50.4 131.2-116.9 114.7 56.4 25.9 43.6 132 336 A Q S S- 0 0 39 -2,-0.6 -1,-0.1 -45,-0.1 -45,-0.1 0.152 78.4-101.9-140.3 11.7 59.7 27.4 42.4 133 337 A S S S+ 0 0 38 3,-0.1 -2,-0.1 1,-0.1 34,-0.0 0.961 93.2 112.5 60.1 54.3 61.3 28.1 45.7 134 338 A H + 0 0 139 2,-0.1 -3,-0.1 0, 0.0 -1,-0.1 0.419 58.7 79.7-124.2 -19.4 60.5 31.9 45.6 135 339 A S S S- 0 0 57 1,-0.1 33,-0.2 0, 0.0 -4,-0.0 -0.419 95.5 -75.3 -86.9 168.2 58.0 31.8 48.5 136 340 A P - 0 0 95 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 -0.262 45.3-116.7 -65.0 147.6 58.9 31.7 52.2 137 341 A P - 0 0 82 0, 0.0 32,-0.2 0, 0.0 2,-0.2 -0.349 43.9 -83.6 -78.4 163.8 60.2 28.6 54.0 138 342 A P > - 0 0 9 0, 0.0 3,-1.1 0, 0.0 2,-0.3 -0.499 55.7-106.5 -68.2 139.0 58.2 27.0 56.8 139 343 A L T 3 S+ 0 0 117 1,-0.2 3,-0.1 -2,-0.2 30,-0.0 -0.496 95.6 4.8 -73.3 130.2 59.0 28.7 60.0 140 344 A G T 3 S+ 0 0 17 -2,-0.3 2,-0.6 1,-0.1 -1,-0.2 0.386 103.0 107.5 83.7 -3.3 61.2 26.9 62.5 141 345 A F < + 0 0 4 -3,-1.1 2,-0.3 91,-0.1 -1,-0.1 -0.928 39.4 162.4-114.8 112.1 61.8 23.9 60.2 142 346 A Q > - 0 0 134 -2,-0.6 3,-2.0 -3,-0.1 21,-0.3 -0.926 48.6 -86.8-126.4 152.7 65.3 23.6 58.6 143 347 A V T 3 S+ 0 0 89 -2,-0.3 21,-0.2 1,-0.2 3,-0.1 -0.308 114.1 31.4 -55.0 131.7 67.1 20.7 57.0 144 348 A G T 3 S+ 0 0 38 19,-3.4 -1,-0.2 1,-0.4 86,-0.2 0.151 84.8 126.3 105.6 -20.3 68.8 18.7 59.7 145 349 A M < - 0 0 24 -3,-2.0 18,-2.3 84,-0.1 -1,-0.4 -0.390 51.8-132.2 -72.2 152.6 66.4 19.2 62.6 146 350 A K E +Mn 162 231C 20 84,-2.0 86,-2.7 16,-0.2 50,-0.4 -0.721 32.7 151.9-106.2 156.0 65.0 16.2 64.5 147 351 A L E -M 161 0C 0 14,-2.4 14,-3.2 -2,-0.3 2,-0.4 -0.918 43.0 -97.9-162.6-178.7 61.4 15.4 65.5 148 352 A E E -MO 160 194C 2 46,-2.8 46,-2.9 -2,-0.3 2,-0.3 -0.933 42.6-178.3-114.0 140.0 59.0 12.6 66.2 149 353 A A E -MO 159 193C 0 10,-2.3 10,-3.0 -2,-0.4 2,-0.2 -0.998 29.5-116.7-147.0 144.8 56.6 11.5 63.4 150 354 A V E -M 158 0C 16 42,-3.0 2,-1.1 -2,-0.3 8,-0.2 -0.539 30.1-127.4 -74.0 134.3 53.9 9.0 62.8 151 355 A D E > -M 154 0C 1 6,-2.5 3,-1.9 3,-0.6 6,-0.4 -0.769 19.2-155.7 -83.0 106.7 54.7 6.4 60.1 152 356 A R T 3 S+ 0 0 90 -2,-1.1 -1,-0.2 30,-0.3 31,-0.0 0.612 93.3 50.3 -63.2 -9.5 51.7 7.0 57.9 153 357 A M T 3 S+ 0 0 126 1,-0.2 -1,-0.3 29,-0.1 -2,-0.1 0.527 126.1 27.2-100.8 -10.5 52.0 3.5 56.5 154 358 A N E X S+M 151 0C 48 -3,-1.9 3,-2.7 3,-0.2 -3,-0.6 -0.483 77.0 179.0-147.5 62.6 52.3 2.0 60.0 155 359 A P E 3 S+ 0 0 87 0, 0.0 -3,-0.1 0, 0.0 -2,-0.0 0.499 73.4 70.1 -48.4 -11.1 50.3 4.6 62.1 156 360 A S E 3 S+ 0 0 92 -5,-0.1 2,-0.5 -6,-0.1 -4,-0.1 0.545 89.8 80.9 -85.7 -5.1 50.8 2.8 65.4 157 361 A L E < - 0 0 45 -3,-2.7 -6,-2.5 -6,-0.4 2,-0.6 -0.884 55.7-173.8-107.7 126.8 54.5 3.8 65.1 158 362 A V E -M 150 0C 2 -2,-0.5 49,-2.8 47,-0.3 -8,-0.3 -0.974 28.6-170.5-115.8 109.9 55.8 7.2 66.2 159 363 A C E -Mp 149 207C 4 -10,-3.0 -10,-2.3 -2,-0.6 2,-0.3 -0.618 32.2 -92.6-109.6 164.8 59.4 7.2 65.1 160 364 A V E +M 148 0C 1 47,-2.0 16,-1.1 -2,-0.2 2,-0.3 -0.570 59.3 177.3 -68.5 125.0 62.6 9.2 65.4 161 365 A A E -MQ 147 175C 0 -14,-3.2 -14,-2.4 -2,-0.3 2,-0.3 -0.865 23.2-153.4-134.7 168.6 62.6 11.5 62.4 162 366 A S E -MQ 146 174C 8 12,-2.7 12,-3.2 -2,-0.3 2,-0.6 -0.942 25.2-117.5-137.8 158.0 64.5 14.3 60.6 163 367 A V E + Q 0 173C 1 -18,-2.3 -19,-3.4 -2,-0.3 10,-0.2 -0.876 36.9 168.4 -94.5 121.6 63.8 17.1 58.2 164 368 A T E + 0 0 56 8,-2.1 2,-0.3 -2,-0.6 -1,-0.1 0.508 58.5 23.2-114.6 -7.2 65.7 16.4 55.1 165 369 A D E - Q 0 172C 17 7,-0.6 7,-2.5 -23,-0.1 2,-0.4 -0.983 55.3-162.7-157.1 148.3 64.4 18.8 52.5 166 370 A V E + Q 0 171C 34 -2,-0.3 2,-0.4 5,-0.2 5,-0.2 -0.980 11.5 174.7-138.3 121.7 62.6 22.2 52.5 167 371 A V E > - Q 0 170C 1 3,-2.1 3,-2.5 -2,-0.4 2,-0.0 -0.980 60.7 -53.5-133.0 119.7 60.8 23.6 49.5 168 372 A D T 3 S- 0 0 16 -2,-0.4 -37,-0.1 1,-0.3 0, 0.0 -0.290 123.4 -13.6 50.0-119.2 58.8 26.8 49.7 169 373 A S T 3 S+ 0 0 66 -32,-0.2 -1,-0.3 -3,-0.1 2,-0.3 0.305 125.6 71.3 -96.4 13.7 56.4 26.4 52.6 170 374 A R E < -Q 167 0C 41 -3,-2.5 -3,-2.1 17,-0.1 2,-0.3 -0.790 57.8-157.8-124.9 167.9 56.8 22.6 53.1 171 375 A F E -QR 166 186C 0 15,-2.5 15,-2.1 -2,-0.3 2,-0.5 -0.953 21.7-115.1-142.0 161.2 59.4 20.1 54.4 172 376 A L E -QR 165 185C 0 -7,-2.5 -8,-2.1 -2,-0.3 -7,-0.6 -0.867 21.8-149.0-102.5 122.6 60.2 16.5 54.0 173 377 A V E -QR 163 184C 0 11,-2.7 11,-1.4 -2,-0.5 2,-0.4 -0.791 19.1-168.2 -90.3 127.2 59.9 14.3 57.0 174 378 A H E -Q 162 0C 35 -12,-3.2 -12,-2.7 -2,-0.5 2,-0.8 -0.951 21.5-128.9-122.3 140.0 62.4 11.4 56.9 175 379 A F E > -Q 161 0C 1 -2,-0.4 3,-1.7 4,-0.3 -14,-0.2 -0.759 39.3-110.7 -90.6 109.3 62.6 8.3 59.1 176 380 A D T 3 S+ 0 0 6 -16,-1.1 34,-1.4 -2,-0.8 -16,-0.1 -0.061 93.8 3.1 -43.9 127.6 66.1 8.0 60.5 177 381 A N T 3 S+ 0 0 103 1,-0.3 2,-0.3 32,-0.2 -1,-0.3 0.651 107.9 100.5 66.3 22.7 68.1 5.1 59.1 178 382 A W S < S- 0 0 48 -3,-1.7 -1,-0.3 1,-0.2 2,-0.0 -0.723 80.1-105.6-118.5 171.3 65.4 3.9 56.6 179 383 A D > - 0 0 90 -2,-0.3 3,-0.5 -3,-0.1 -4,-0.3 -0.097 48.3 -88.0 -80.8-162.6 65.5 4.8 52.9 180 384 A D G > S+ 0 0 10 1,-0.2 3,-1.5 2,-0.1 -131,-0.1 0.373 99.1 103.9 -92.1 7.6 63.0 7.4 51.8 181 385 A T G 3 S+ 0 0 41 1,-0.3 -1,-0.2 -134,-0.1 -7,-0.0 0.785 86.9 41.6 -59.7 -26.6 60.1 5.0 51.1 182 386 A Y G < S+ 0 0 45 -3,-0.5 -30,-0.3 -7,-0.1 -1,-0.3 0.397 91.8 112.7-100.4 2.0 58.4 6.2 54.3 183 387 A D < - 0 0 11 -3,-1.5 2,-0.3 -8,-0.1 -9,-0.2 -0.332 42.9-175.8 -73.8 156.3 59.1 9.9 54.0 184 388 A Y E -R 173 0C 22 -11,-1.4 -11,-2.7 -136,-0.1 2,-0.2 -0.990 23.8-122.2-154.0 146.6 56.4 12.4 53.3 185 389 A W E +R 172 0C 29 -2,-0.3 2,-0.3 -13,-0.2 -13,-0.2 -0.611 44.7 142.1 -85.9 147.1 56.1 16.1 52.6 186 390 A C E -R 171 0C 12 -15,-2.1 -15,-2.5 -2,-0.2 -2,-0.0 -0.943 39.2-111.1-166.4-177.3 54.0 18.2 55.0 187 391 A D > - 0 0 46 -2,-0.3 3,-2.3 -17,-0.2 -17,-0.1 -0.738 46.1 -83.7-123.1 173.7 53.7 21.6 56.7 188 392 A P T 3 S+ 0 0 24 0, 0.0 50,-1.3 0, 0.0 5,-0.1 0.664 122.9 58.9 -51.4 -20.7 54.0 22.9 60.3 189 393 A S T 3 S+ 0 0 25 48,-0.2 51,-2.1 50,-0.1 48,-0.1 0.396 71.8 132.8 -93.8 3.7 50.3 22.0 60.9 190 394 A S X - 0 0 5 -3,-2.3 3,-1.0 49,-0.2 49,-0.1 -0.295 52.2-147.2 -56.3 131.5 50.6 18.3 60.1 191 395 A P T 3 S+ 0 0 19 0, 0.0 -1,-0.2 0, 0.0 48,-0.1 0.474 92.4 68.6 -79.9 1.5 48.8 16.2 62.8 192 396 A Y T 3 S+ 0 0 35 -42,-0.1 -42,-3.0 -43,-0.1 2,-0.3 0.447 88.8 70.9 -98.6 -2.0 51.4 13.5 62.2 193 397 A I E < +O 149 0C 7 -3,-1.0 -44,-0.2 -44,-0.2 46,-0.1 -0.900 54.1 177.8-120.0 148.1 54.5 15.3 63.6 194 398 A H E -O 148 0C 34 -46,-2.9 -46,-2.8 -2,-0.3 3,-0.1 -0.967 33.9 -96.0-142.4 156.7 55.5 16.2 67.1 195 399 A P > - 0 0 23 0, 0.0 3,-1.9 0, 0.0 4,-0.2 -0.297 59.0 -77.2 -71.7 160.2 58.5 17.8 68.9 196 400 A V T 3 S+ 0 0 31 36,-0.4 38,-0.1 -50,-0.4 35,-0.0 -0.281 121.3 29.1 -54.0 137.7 61.2 15.7 70.4 197 401 A G T 3> S+ 0 0 12 -3,-0.1 4,-1.9 -50,-0.0 -1,-0.3 0.401 83.1 118.4 90.6 -2.6 60.1 14.2 73.7 198 402 A W H <> S+ 0 0 62 -3,-1.9 4,-1.4 1,-0.2 6,-0.2 0.952 72.3 52.0 -61.3 -52.5 56.4 14.1 72.7 199 403 A C H >>S+ 0 0 0 1,-0.2 5,-2.0 -4,-0.2 4,-1.1 0.860 110.2 51.3 -52.5 -38.4 56.1 10.3 73.0 200 404 A Q H 45S+ 0 0 139 1,-0.2 3,-0.4 2,-0.2 -1,-0.2 0.903 108.7 48.1 -68.0 -43.1 57.6 10.5 76.5 201 405 A K H <5S+ 0 0 167 -4,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.675 115.2 49.1 -70.9 -16.1 55.2 13.2 77.7 202 406 A Q H <5S- 0 0 112 -4,-1.4 -1,-0.2 2,-0.2 -2,-0.2 0.637 106.6-123.3 -96.7 -18.5 52.4 11.1 76.3 203 407 A G T <5S+ 0 0 74 -4,-1.1 -3,-0.2 1,-0.4 -4,-0.1 0.653 70.8 130.8 81.9 13.4 53.3 7.8 77.8 204 408 A K < - 0 0 78 -5,-2.0 -1,-0.4 -6,-0.2 -2,-0.2 -0.771 64.1-104.7 -99.0 146.3 53.4 6.4 74.3 205 409 A P - 0 0 98 0, 0.0 2,-0.4 0, 0.0 -47,-0.3 -0.369 27.3-138.7 -70.9 150.6 56.4 4.4 73.1 206 410 A L - 0 0 44 -49,-0.1 -47,-0.2 12,-0.1 12,-0.1 -0.907 9.6-137.9-108.6 136.2 58.9 5.9 70.8 207 411 A T B -p 159 0C 44 -49,-2.8 -47,-2.0 -2,-0.4 3,-0.1 -0.848 22.3-143.7 -96.7 116.5 60.3 3.9 67.9 208 412 A P - 0 0 28 0, 0.0 3,-0.2 0, 0.0 4,-0.1 -0.248 36.2 -68.1 -74.9 165.5 64.1 4.4 67.5 209 413 A P S > S- 0 0 7 0, 0.0 3,-1.9 0, 0.0 -32,-0.2 -0.070 72.5 -75.4 -49.2 151.3 66.0 4.5 64.2 210 414 A Q T 3 S- 0 0 64 -34,-1.4 -3,-0.0 1,-0.3 0, 0.0 -0.253 115.4 -2.5 -54.6 131.8 66.2 1.3 62.3 211 415 A D T 3 S+ 0 0 138 1,-0.2 -1,-0.3 -3,-0.2 3,-0.1 0.757 85.9 172.7 56.2 29.3 68.7 -1.1 63.8 212 416 A Y < - 0 0 26 -3,-1.9 -1,-0.2 -4,-0.1 6,-0.1 -0.527 41.7-103.0 -68.5 129.8 69.7 1.4 66.5 213 417 A P S S+ 0 0 94 0, 0.0 4,-0.1 0, 0.0 -1,-0.1 -0.277 99.8 0.5 -58.0 132.8 72.0 -0.3 69.0 214 418 A D S > S- 0 0 97 1,-0.1 3,-2.2 2,-0.1 -2,-0.0 0.947 79.6-175.6 50.5 56.0 70.3 -1.3 72.3 215 419 A P G > S+ 0 0 61 0, 0.0 3,-1.7 0, 0.0 -1,-0.1 0.798 72.3 70.8 -48.1 -40.9 67.0 0.2 71.0 216 420 A D G 3 S+ 0 0 147 1,-0.3 -2,-0.1 -8,-0.0 0, 0.0 0.721 102.7 45.0 -54.9 -21.6 65.3 -0.4 74.3 217 421 A N G < S+ 0 0 112 -3,-2.2 -1,-0.3 -4,-0.1 2,-0.1 -0.116 76.1 156.2-118.6 38.5 67.4 2.3 75.8 218 422 A F < - 0 0 32 -3,-1.7 2,-0.5 -12,-0.1 -12,-0.1 -0.424 20.6-167.9 -66.2 133.8 67.2 5.1 73.2 219 423 A X > - 0 0 174 -2,-0.1 4,-2.5 1,-0.1 3,-0.4 -0.963 16.2-153.6-129.9 114.4 67.9 8.6 74.6 220 424 A W H > S+ 0 0 11 -2,-0.5 4,-3.0 1,-0.2 5,-0.3 0.881 96.1 52.7 -51.8 -47.8 67.1 11.7 72.6 221 425 A E H > S+ 0 0 128 1,-0.2 4,-1.4 2,-0.2 -1,-0.2 0.887 112.8 46.3 -58.9 -37.0 69.7 13.9 74.3 222 426 A K H > S+ 0 0 111 -3,-0.4 4,-2.7 2,-0.2 -2,-0.2 0.909 112.8 48.2 -70.8 -43.3 72.3 11.3 73.6 223 427 A Y H X S+ 0 0 27 -4,-2.5 4,-2.2 1,-0.2 6,-0.3 0.897 111.9 50.1 -64.3 -40.9 71.2 10.8 69.9 224 428 A L H X>S+ 0 0 19 -4,-3.0 4,-1.6 -5,-0.2 5,-0.7 0.834 111.7 48.8 -66.8 -31.8 71.2 14.6 69.4 225 429 A E H <5S+ 0 0 164 -4,-1.4 -2,-0.2 -5,-0.3 -1,-0.2 0.918 110.7 50.4 -72.7 -42.5 74.7 14.8 70.9 226 430 A E H <5S+ 0 0 110 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.860 120.7 34.9 -61.6 -38.4 75.9 11.9 68.7 227 431 A T H <5S- 0 0 63 -4,-2.2 -1,-0.2 -5,-0.1 -2,-0.2 0.636 96.6-133.9 -92.8 -16.7 74.5 13.7 65.6 228 432 A G T <5 + 0 0 72 -4,-1.6 2,-0.2 1,-0.3 -3,-0.2 0.678 61.1 140.3 69.5 15.0 75.1 17.3 66.6 229 433 A A < - 0 0 24 -5,-0.7 2,-0.3 -6,-0.3 -1,-0.3 -0.586 45.7-138.2 -91.8 152.7 71.6 17.9 65.4 230 434 A S - 0 0 71 -2,-0.2 -84,-2.0 -86,-0.2 2,-0.2 -0.744 22.0-108.8-107.7 159.1 69.1 20.2 67.1 231 435 A A B -n 146 0C 35 -2,-0.3 -84,-0.2 -86,-0.2 -86,-0.1 -0.597 37.1-101.5 -85.2 145.0 65.4 19.5 67.7 232 436 A V - 0 0 2 -86,-2.7 -36,-0.4 -2,-0.2 -91,-0.1 -0.495 55.2-105.6 -59.1 131.8 62.8 21.4 65.7 233 437 A P > - 0 0 40 0, 0.0 3,-1.8 0, 0.0 4,-0.4 -0.351 18.9-122.9 -66.0 144.4 61.7 23.9 68.3 234 438 A T G > S+ 0 0 102 1,-0.3 3,-1.4 2,-0.2 -2,-0.1 0.825 107.8 65.1 -54.7 -36.8 58.3 23.4 70.0 235 439 A W G 3 S+ 0 0 160 1,-0.3 -1,-0.3 3,-0.0 -3,-0.0 0.730 92.1 66.7 -61.3 -19.9 57.0 26.8 69.0 236 440 A A G < S+ 0 0 0 -3,-1.8 2,-0.8 -96,-0.1 -1,-0.3 0.754 78.9 88.9 -73.0 -26.6 57.2 25.6 65.3 237 441 A F < + 0 0 39 -3,-1.4 2,-0.3 -4,-0.4 -48,-0.2 -0.663 45.5 165.9 -80.5 109.4 54.5 23.0 65.7 238 442 A K - 0 0 115 -50,-1.3 -1,-0.1 -2,-0.8 -3,-0.0 -0.620 22.5-157.5-122.3 70.4 51.1 24.5 64.9 239 443 A V - 0 0 94 -2,-0.3 -49,-0.2 1,-0.1 -50,-0.1 -0.121 19.5-113.8 -52.9 140.3 48.7 21.6 64.4 240 444 A R - 0 0 49 -51,-2.1 -1,-0.1 1,-0.1 3,-0.1 -0.299 30.4-100.0 -74.3 157.7 45.6 22.3 62.4 241 445 A P - 0 0 105 0, 0.0 -1,-0.1 0, 0.0 -52,-0.0 -0.441 50.5 -89.1 -74.8 150.3 42.0 22.2 63.8 242 446 A P - 0 0 68 0, 0.0 31,-0.2 0, 0.0 30,-0.1 -0.244 51.5-106.4 -57.3 152.7 40.0 19.0 63.1 243 447 A H - 0 0 36 29,-2.0 31,-0.1 28,-0.2 -222,-0.1 -0.262 16.1-133.0 -76.1 169.9 38.1 19.2 59.9 244 448 A S + 0 0 76 -224,-0.2 2,-0.3 2,-0.1 -1,-0.1 0.033 53.0 136.7-115.3 26.4 34.3 19.7 59.7 245 449 A F - 0 0 2 -225,-0.1 2,-0.3 -229,-0.1 29,-0.1 -0.583 38.6-157.0 -71.8 132.8 33.3 17.1 57.2 246 450 A L > - 0 0 108 -2,-0.3 3,-1.8 1,-0.1 21,-0.3 -0.857 27.6 -88.0-113.0 149.1 30.1 15.2 58.5 247 451 A V T 3 S+ 0 0 64 -2,-0.3 21,-0.2 1,-0.2 3,-0.1 -0.168 110.3 24.3 -54.4 146.2 29.0 11.8 57.4 248 452 A N T 3 S+ 0 0 117 19,-3.4 -234,-0.4 1,-0.3 -1,-0.2 0.243 83.5 134.5 80.9 -10.2 26.7 11.6 54.4 249 453 A M < - 0 0 16 -3,-1.8 18,-2.2 18,-0.2 -1,-0.3 -0.470 51.0-133.4 -66.3 143.4 28.0 14.9 52.9 250 454 A K E +aB 15 266A 17 -236,-2.0 -234,-2.8 16,-0.2 50,-0.4 -0.712 37.2 142.9-103.9 154.3 28.7 14.4 49.2 251 455 A L E - B 0 265A 0 14,-2.7 14,-3.1 -2,-0.3 2,-0.4 -0.863 45.6 -85.8-161.7-168.4 31.7 15.4 47.2 252 456 A E E +CB 298 264A 1 46,-2.7 46,-3.0 -2,-0.2 2,-0.3 -0.949 39.4 177.8-119.9 138.2 34.0 14.4 44.3 253 457 A A E -CB 297 263A 0 10,-2.1 10,-2.7 -2,-0.4 44,-0.2 -0.999 32.9-109.0-144.7 145.3 37.1 12.2 44.6 254 458 A V E - B 0 262A 8 42,-2.4 2,-0.3 -2,-0.3 8,-0.3 -0.467 42.9-111.6 -67.7 138.4 39.7 10.6 42.4 255 459 A D - 0 0 6 6,-3.2 6,-0.2 3,-0.4 -1,-0.1 -0.563 20.2-152.4 -73.2 129.5 39.3 6.8 42.1 256 460 A R S S+ 0 0 130 -2,-0.3 -1,-0.1 1,-0.2 -2,-0.0 0.643 93.2 48.8 -80.6 -12.5 42.2 5.1 43.8 257 461 A R S S+ 0 0 164 1,-0.3 -1,-0.2 4,-0.0 -2,-0.0 0.832 128.1 22.1 -92.3 -36.6 42.0 2.0 41.6 258 462 A N S > S- 0 0 78 3,-0.1 3,-2.4 1,-0.1 -3,-0.4 -0.780 71.4-168.7-132.0 87.7 42.0 4.0 38.3 259 463 A P T 3 S+ 0 0 55 0, 0.0 -1,-0.1 0, 0.0 -4,-0.1 0.603 80.8 72.6 -51.1 -17.7 43.4 7.5 39.0 260 464 A A T 3 S+ 0 0 30 -6,-0.1 2,-0.2 -182,-0.0 -183,-0.0 0.824 92.2 73.0 -69.8 -26.3 42.2 8.7 35.6 261 465 A L < - 0 0 40 -3,-2.4 -6,-3.2 -6,-0.2 2,-0.4 -0.601 59.6-166.0 -96.0 149.5 38.7 8.7 37.0 262 466 A I E -B 254 0A 0 47,-0.4 49,-3.0 -8,-0.3 2,-0.3 -0.999 19.7-167.1-128.9 129.8 36.9 11.0 39.4 263 467 A R E -Bd 253 311A 28 -10,-2.7 -10,-2.1 -2,-0.4 2,-0.2 -0.805 30.5 -93.0-122.9 162.8 33.6 9.8 40.9 264 468 A V E -B 252 0A 1 47,-1.9 16,-0.7 -2,-0.3 2,-0.3 -0.498 56.7-176.7 -66.7 133.2 30.6 11.0 42.9 265 469 A A E -BE 251 279A 0 -14,-3.1 -14,-2.7 14,-0.2 2,-0.3 -0.910 24.0-153.4-138.9 163.7 31.4 10.3 46.5 266 470 A S E -BE 250 278A 9 12,-2.5 12,-2.4 -2,-0.3 2,-0.7 -0.952 31.5-109.0-133.6 152.5 30.0 10.5 50.1 267 471 A V E + E 0 277A 1 -18,-2.2 -19,-3.4 -2,-0.3 10,-0.2 -0.754 33.8 179.8 -83.4 113.6 31.7 10.8 53.5 268 472 A E E - 0 0 74 8,-3.4 2,-0.3 -2,-0.7 -1,-0.2 0.826 63.7 -13.3 -84.5 -37.4 31.2 7.4 55.2 269 473 A D E - E 0 276A 76 7,-0.8 7,-3.2 -23,-0.1 2,-0.3 -0.970 64.5-142.6-158.9 165.8 32.9 8.1 58.5 270 474 A V E - E 0 275A 48 -2,-0.3 2,-0.2 5,-0.2 5,-0.2 -0.936 12.2-177.6-139.1 161.3 35.2 10.7 60.1 271 475 A E - 0 0 84 3,-2.3 -28,-0.2 -2,-0.3 5,-0.0 -0.710 55.7 -82.0-135.8-175.1 38.1 11.2 62.5 272 476 A D S S+ 0 0 107 -2,-0.2 -29,-2.0 1,-0.2 3,-0.0 0.899 125.6 9.7 -62.1 -38.0 39.7 14.4 63.6 273 477 A H S S+ 0 0 40 -31,-0.2 19,-2.3 -82,-0.0 20,-0.3 0.434 122.5 58.2-126.8 0.2 41.9 14.7 60.5 274 478 A R E - F 0 291A 70 17,-0.3 -3,-2.3 18,-0.1 2,-0.4 -0.907 55.5-155.5-133.6 158.6 40.6 12.1 58.0 275 479 A I E -EF 270 290A 0 15,-2.6 15,-1.9 -2,-0.3 2,-0.6 -0.970 20.9-126.9-130.9 146.6 37.4 11.1 56.3 276 480 A K E -EF 269 289A 63 -7,-3.2 -8,-3.4 -2,-0.4 -7,-0.8 -0.866 27.4-145.2 -97.2 120.6 36.4 7.7 54.9 277 481 A I E -EF 267 288A 0 11,-3.4 11,-1.8 -2,-0.6 2,-0.4 -0.704 14.8-171.6 -89.8 135.4 35.3 8.0 51.3 278 482 A H E -E 266 0A 22 -12,-2.4 -12,-2.5 -2,-0.4 2,-0.9 -0.984 20.4-135.3-124.1 132.6 32.6 5.9 49.8 279 483 A F E > -E 265 0A 8 -2,-0.4 3,-2.6 4,-0.3 -14,-0.2 -0.799 31.8-116.3 -92.6 110.0 31.9 5.8 46.1 280 484 A D T 3 S+ 0 0 6 -2,-0.9 34,-1.5 -16,-0.7 -16,-0.1 -0.092 97.3 14.9 -43.0 128.3 28.1 6.0 45.5 281 485 A G T 3 S+ 0 0 44 1,-0.3 -1,-0.3 32,-0.3 2,-0.2 0.332 108.8 100.8 86.9 -8.9 26.7 2.9 43.9 282 486 A W S < S- 0 0 58 -3,-2.6 -1,-0.3 1,-0.1 5,-0.0 -0.654 83.4 -80.0-108.1 166.3 29.8 0.8 44.6 283 487 A S > - 0 0 72 -2,-0.2 3,-1.8 1,-0.1 -4,-0.3 -0.311 32.1-128.7 -61.7 142.8 30.7 -1.8 47.2 284 488 A H G > S+ 0 0 109 1,-0.3 3,-1.4 2,-0.2 -1,-0.1 0.601 102.6 82.3 -67.5 -10.4 31.7 -0.4 50.6 285 489 A G G 3 S+ 0 0 68 1,-0.3 -1,-0.3 -7,-0.0 -2,-0.1 0.771 87.6 55.2 -64.5 -23.3 34.7 -2.7 50.2 286 490 A Y G < S+ 0 0 90 -3,-1.8 -1,-0.3 -7,-0.1 -2,-0.2 0.530 80.4 120.1 -85.6 -9.4 36.2 0.1 48.1 287 491 A D < - 0 0 20 -3,-1.4 2,-0.3 -4,-0.2 -9,-0.2 -0.240 43.8-174.2 -56.0 144.1 35.7 2.7 50.9 288 492 A F E -F 277 0A 28 -11,-1.8 -11,-3.4 2,-0.0 2,-0.3 -0.999 26.1-119.7-147.8 148.3 39.0 4.3 52.0 289 493 A W E +F 276 0A 64 -2,-0.3 2,-0.3 -13,-0.3 -13,-0.2 -0.602 36.4 172.4 -83.5 145.2 40.4 6.6 54.6 290 494 A I E -F 275 0A 7 -15,-1.9 -15,-2.6 -2,-0.3 2,-0.1 -0.990 37.5 -99.5-153.7 145.2 42.0 9.8 53.3 291 495 A D E > -F 274 0A 20 -2,-0.3 3,-2.0 -17,-0.2 -17,-0.3 -0.407 31.8-124.9 -65.7 141.6 43.4 12.9 54.9 292 496 A A T 3 S+ 0 0 12 -19,-2.3 -270,-0.3 1,-0.3 -1,-0.1 0.690 110.5 51.6 -61.6 -19.7 41.0 15.9 54.7 293 497 A D T 3 S+ 0 0 53 -20,-0.3 -1,-0.3 -272,-0.1 -2,-0.1 0.202 78.0 134.4-101.7 14.4 43.7 18.0 53.0 294 498 A H X - 0 0 47 -3,-2.0 3,-1.1 1,-0.1 -4,-0.0 -0.396 60.4-131.6 -65.0 137.4 44.5 15.4 50.3 295 499 A P T 3 S+ 0 0 68 0, 0.0 -1,-0.1 0, 0.0 -3,-0.0 0.667 97.7 68.0 -66.0 -12.1 44.8 17.0 46.9 296 500 A D T 3 S+ 0 0 33 -42,-0.1 -42,-2.4 -43,-0.0 2,-0.4 0.136 82.8 76.8 -97.7 21.4 42.5 14.4 45.4 297 501 A I E < +C 253 0A 0 -3,-1.1 -44,-0.2 -44,-0.2 -35,-0.0 -0.981 59.2 173.7-125.1 141.3 39.1 15.2 47.0 298 502 A H E -C 252 0A 1 -46,-3.0 -46,-2.7 -2,-0.4 -272,-0.1 -0.940 33.3 -92.8-144.1 163.1 37.1 18.2 45.8 299 503 A P > - 0 0 6 0, 0.0 3,-1.9 0, 0.0 4,-0.2 -0.397 58.8 -80.8 -76.4 158.1 33.8 19.9 46.4 300 504 A A T 3 S+ 0 0 23 -50,-0.4 -282,-0.1 -284,-0.4 -285,-0.0 -0.299 119.3 34.6 -55.4 137.7 30.8 19.1 44.1 301 505 A G T 3> S+ 0 0 14 -3,-0.1 4,-2.5 -50,-0.0 -1,-0.2 0.256 81.8 112.1 99.3 -11.3 31.1 20.9 40.9 302 506 A W H <> S+ 0 0 4 -3,-1.9 4,-1.9 2,-0.2 5,-0.2 0.940 78.5 46.9 -60.0 -50.1 34.9 20.8 40.6 303 507 A C H >>S+ 0 0 1 -4,-0.2 5,-2.4 1,-0.2 4,-1.6 0.931 113.8 47.8 -58.8 -48.2 34.9 18.4 37.6 304 508 A S H 45S+ 0 0 106 1,-0.2 3,-0.2 2,-0.2 -1,-0.2 0.933 114.4 45.4 -59.4 -47.9 32.3 20.5 35.7 305 509 A K H <5S+ 0 0 137 -4,-2.5 -1,-0.2 1,-0.2 -2,-0.2 0.772 118.8 41.9 -69.2 -26.6 34.0 23.8 36.4 306 510 A T H <5S- 0 0 23 -4,-1.9 -1,-0.2 -5,-0.2 -2,-0.2 0.583 112.7-112.2 -96.6 -13.2 37.5 22.5 35.5 307 511 A G T <5 + 0 0 55 -4,-1.6 -246,-0.5 1,-0.3 -3,-0.2 0.790 69.1 135.8 88.2 29.3 36.5 20.4 32.5 308 512 A H < - 0 0 9 -5,-2.4 -1,-0.3 -6,-0.2 -2,-0.1 -0.900 59.2-109.9-110.5 136.3 37.1 16.9 33.8 309 513 A P - 0 0 75 0, 0.0 2,-0.5 0, 0.0 -47,-0.4 -0.376 28.8-148.4 -64.2 145.1 34.6 14.1 33.3 310 514 A L - 0 0 41 -49,-0.1 -47,-0.2 -308,-0.1 -308,-0.1 -0.970 8.4-136.2-116.9 126.1 32.8 13.0 36.4 311 515 A Q B -d 263 0A 62 -49,-3.0 -47,-1.9 -2,-0.5 3,-0.1 -0.711 22.0-139.7 -83.9 119.0 31.7 9.4 36.8 312 516 A P - 0 0 54 0, 0.0 3,-0.2 0, 0.0 -1,-0.0 -0.250 43.1 -62.1 -71.3 165.9 28.1 9.2 38.1 313 517 A P - 0 0 17 0, 0.0 2,-0.3 0, 0.0 -32,-0.3 -0.122 66.9 -89.2 -49.0 139.0 27.1 6.5 40.7 314 518 A L 0 0 88 -34,-1.5 -3,-0.0 1,-0.2 -35,-0.0 -0.343 360.0 360.0 -53.4 110.9 27.4 2.9 39.6 315 519 A G 0 0 131 -2,-0.3 -1,-0.2 -3,-0.2 -34,-0.1 -0.460 360.0 360.0 87.3 360.0 24.0 2.4 38.1 316 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 317 1 A X 0 0 142 0, 0.0 -163,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 58.1 -3.1 58.4