==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=11-DEC-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER MEMBRANE PROTEIN/SIGNALING PROTEIN 19-APR-11 3RL7 . COMPND 2 MOLECULE: DISKS LARGE HOMOLOG 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR Z.ZHANG,H.LI,G.WU . 563 15 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 30033.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 381 67.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 186 33.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 12 2.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 66 11.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 41 7.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 64 11.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 6 0 0 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 11 12 1 12 0 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 219 B M 0 0 140 0, 0.0 2,-0.1 0, 0.0 153,-0.1 0.000 360.0 360.0 360.0-164.9 33.5 -24.1 13.8 2 220 B Y - 0 0 74 151,-0.3 2,-0.4 88,-0.1 88,-0.2 -0.411 360.0-138.9 -75.2 163.0 35.0 -23.3 10.4 3 221 B E E -A 89 0A 68 86,-1.7 86,-2.1 -2,-0.1 2,-0.4 -0.972 7.1-147.5-129.8 140.6 37.6 -25.7 8.9 4 222 B Y E +A 88 0A 44 -2,-0.4 2,-0.3 84,-0.2 84,-0.2 -0.898 21.4 167.0-117.3 141.9 40.9 -24.8 7.1 5 223 B E E -A 87 0A 57 82,-1.8 82,-1.1 -2,-0.4 2,-0.4 -0.842 27.0-135.2-142.7 165.8 42.5 -26.8 4.3 6 224 B E E -A 86 0A 58 -2,-0.3 2,-0.5 80,-0.2 80,-0.2 -0.977 17.5-172.0-135.4 127.5 45.2 -26.6 1.6 7 225 B I E -A 85 0A 0 78,-2.7 78,-3.0 -2,-0.4 2,-0.6 -0.966 6.4-161.5-124.2 117.8 44.7 -27.8 -1.9 8 226 B T E -A 84 0A 55 -2,-0.5 2,-0.4 76,-0.2 76,-0.2 -0.890 15.8-177.9-101.9 115.9 47.5 -28.0 -4.5 9 227 B L E -A 83 0A 4 74,-2.4 74,-3.0 -2,-0.6 2,-0.5 -0.885 24.4-138.3-113.2 143.8 46.3 -28.2 -8.1 10 228 B E E -A 82 0A 147 -2,-0.4 72,-0.2 72,-0.2 71,-0.1 -0.897 35.7-115.8 -92.0 128.3 48.3 -28.5 -11.3 11 229 B R - 0 0 63 70,-3.1 5,-0.2 -2,-0.5 2,-0.1 -0.385 32.7-153.2 -63.3 137.0 46.7 -26.3 -14.0 12 230 B G B > -G 15 0B 38 3,-4.6 3,-1.0 -2,-0.1 -1,-0.1 -0.237 35.8 -84.9 -97.5-169.1 45.3 -28.2 -17.0 13 231 B N T 3 S+ 0 0 170 1,-0.3 3,-0.1 -2,-0.1 -2,-0.1 0.803 132.7 39.7 -69.8 -32.1 44.7 -27.2 -20.6 14 232 B S T 3 S- 0 0 108 1,-0.3 3,-0.5 0, 0.0 2,-0.4 0.021 123.9-105.6-104.3 24.6 41.4 -25.5 -19.7 15 233 B G B < -G 12 0B 21 -3,-1.0 -3,-4.6 1,-0.2 -1,-0.3 -0.737 66.3 -26.4 104.0-137.8 42.8 -24.1 -16.5 16 234 B L S S- 0 0 16 -2,-0.4 28,-1.4 -5,-0.2 -1,-0.2 0.558 81.2-116.0 -99.7 -12.4 42.2 -25.1 -12.8 17 235 B G S S+ 0 0 9 -3,-0.5 22,-2.6 1,-0.2 2,-0.3 0.665 77.0 84.9 90.6 20.1 38.8 -26.7 -13.3 18 236 B F E -B 38 0A 12 20,-0.2 2,-0.3 26,-0.1 -1,-0.2 -0.980 60.8-133.3-147.1 159.8 36.5 -24.4 -11.2 19 237 B S E -B 37 0A 8 18,-2.1 17,-2.3 -2,-0.3 18,-1.0 -0.833 21.1-155.2-110.5 153.8 34.5 -21.2 -11.3 20 238 B I E -BC 35 552A 4 532,-2.5 532,-2.0 -2,-0.3 2,-0.3 -0.926 11.2-178.4-128.5 150.8 34.5 -18.5 -8.6 21 239 B A E +BC 34 551A 9 13,-2.7 13,-2.4 -2,-0.3 530,-0.1 -0.801 42.0 50.5-130.9 179.0 32.1 -15.8 -7.4 22 240 B G + 0 0 7 528,-0.5 11,-0.2 -2,-0.3 2,-0.2 -0.372 39.1 150.7 90.8-166.3 32.3 -13.0 -4.8 23 241 B G > - 0 0 2 8,-1.7 3,-0.5 9,-0.3 45,-0.2 -0.545 64.3 -70.9 115.5 171.6 34.8 -10.3 -3.9 24 242 B T T 3 S+ 0 0 69 43,-2.3 44,-0.2 1,-0.2 -1,-0.1 0.699 132.0 43.8 -75.0 -23.1 34.5 -6.9 -2.3 25 243 B D T 3 S+ 0 0 90 42,-0.2 -1,-0.2 -3,-0.1 43,-0.1 0.404 97.5 98.1-100.9 -2.0 32.8 -5.3 -5.4 26 244 B N S < S- 0 0 25 -3,-0.5 -3,-0.2 5,-0.2 -5,-0.0 -0.683 92.3 -83.8 -92.3 141.4 30.5 -8.2 -5.9 27 245 B P 0 0 30 0, 0.0 -1,-0.1 0, 0.0 -5,-0.1 -0.172 360.0 360.0 -37.8 118.9 26.8 -8.4 -4.8 28 246 B H 0 0 95 280,-0.1 -2,-0.1 -4,-0.1 281,-0.0 -0.311 360.0 360.0 68.2 360.0 27.0 -9.6 -1.1 29 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 30 250 B D 0 0 114 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 126.7 31.2 -12.0 4.2 31 251 B S + 0 0 31 34,-0.2 -8,-1.7 -9,-0.1 -5,-0.2 0.193 360.0 144.6-113.8 11.5 32.6 -10.7 0.9 32 252 B S - 0 0 13 -10,-0.2 -9,-0.3 1,-0.1 2,-0.3 -0.076 56.7-107.8 -63.4 148.5 34.9 -13.7 0.4 33 253 B I - 0 0 2 23,-0.5 23,-1.7 31,-0.5 2,-0.3 -0.575 48.8-179.8 -67.3 132.4 35.8 -15.3 -3.0 34 254 B F E -BD 21 55A 30 -13,-2.4 -13,-2.7 -2,-0.3 2,-0.3 -0.958 30.7-101.4-141.6 158.1 34.1 -18.7 -3.2 35 255 B I E +B 20 0A 0 19,-2.0 18,-2.0 -2,-0.3 -15,-0.3 -0.569 32.0 169.2 -78.6 137.6 33.7 -21.7 -5.6 36 256 B T E + 0 0 5 -17,-2.3 2,-0.3 1,-0.4 -16,-0.2 0.607 66.4 23.7-117.9 -27.3 30.5 -21.9 -7.6 37 257 B K E -B 19 0A 88 -18,-1.0 -18,-2.1 14,-0.1 2,-0.5 -0.999 51.6-160.0-146.0 135.3 31.3 -24.7 -10.0 38 258 B I E -B 18 0A 47 -2,-0.3 -20,-0.2 -20,-0.2 2,-0.1 -0.991 30.7-136.3-110.3 120.0 33.6 -27.7 -10.1 39 259 B I > - 0 0 56 -22,-2.6 3,-0.9 -2,-0.5 6,-0.3 -0.454 24.0-103.5 -76.3 148.5 34.0 -28.8 -13.8 40 260 B T T 3 S+ 0 0 142 1,-0.2 -1,-0.1 -2,-0.1 3,-0.1 -0.584 103.4 5.5 -77.3 130.0 33.8 -32.5 -14.6 41 261 B G T 3 S+ 0 0 49 -2,-0.3 -1,-0.2 1,-0.3 -2,-0.0 0.321 100.2 138.4 80.7 -7.1 37.2 -34.1 -15.3 42 262 B G S <> S- 0 0 13 -3,-0.9 4,-3.4 -25,-0.2 5,-0.3 -0.156 71.6-101.8 -67.4 163.9 38.9 -30.8 -14.3 43 263 B A H > S+ 0 0 17 1,-0.2 4,-2.5 2,-0.2 -26,-0.2 0.894 124.2 48.6 -53.0 -46.4 42.1 -30.5 -12.2 44 264 B A H > S+ 0 0 0 -28,-1.4 4,-2.7 2,-0.2 5,-0.5 0.898 115.2 44.8 -61.0 -43.3 40.1 -29.6 -9.1 45 265 B A H 4 S+ 0 0 39 -6,-0.3 -2,-0.2 2,-0.2 -1,-0.2 0.887 112.0 51.4 -68.0 -42.8 37.7 -32.5 -9.7 46 266 B Q H < S+ 0 0 151 -4,-3.4 -2,-0.2 1,-0.2 -1,-0.2 0.890 113.0 45.9 -63.5 -39.6 40.5 -35.0 -10.5 47 267 B D H < S- 0 0 61 -4,-2.5 -2,-0.2 -5,-0.3 -1,-0.2 0.945 96.2-157.8 -64.5 -50.3 42.2 -33.9 -7.2 48 268 B G < + 0 0 40 -4,-2.7 -3,-0.1 -5,-0.2 -4,-0.1 0.618 60.9 95.5 86.1 15.9 38.8 -34.2 -5.4 49 269 B R + 0 0 87 -5,-0.5 2,-0.2 2,-0.0 -4,-0.1 0.785 59.6 88.0-100.2 -38.5 39.3 -31.9 -2.3 50 270 B L - 0 0 8 -6,-0.5 2,-0.3 4,-0.0 -2,-0.1 -0.448 59.3-167.3 -71.0 129.8 37.8 -28.6 -3.5 51 271 B R > - 0 0 138 -2,-0.2 3,-1.6 -14,-0.0 -16,-0.3 -0.856 30.0 -99.9-115.0 151.3 34.1 -28.2 -2.9 52 272 B V T 3 S+ 0 0 46 -2,-0.3 -16,-0.2 1,-0.2 3,-0.1 -0.482 112.8 34.7 -61.2 138.9 31.5 -25.7 -4.1 53 273 B N T 3 S+ 0 0 33 -18,-2.0 -1,-0.2 1,-0.4 37,-0.1 0.204 85.6 136.2 91.2 -11.3 31.0 -23.1 -1.4 54 274 B D < - 0 0 2 -3,-1.6 -19,-2.0 35,-0.1 2,-0.5 -0.405 51.9-132.6 -61.0 141.0 34.6 -23.3 -0.3 55 275 B C E -DE 34 88A 0 33,-2.8 33,-1.6 -21,-0.2 2,-0.6 -0.891 9.2-142.2-101.6 124.4 36.2 -19.8 0.4 56 276 B I E + E 0 87A 1 -23,-1.7 -23,-0.5 -2,-0.5 31,-0.2 -0.763 24.6 171.3 -84.8 120.1 39.6 -19.1 -1.2 57 277 B L E + 0 0 25 29,-3.8 7,-1.8 -2,-0.6 8,-0.5 0.722 64.6 14.1 -98.5 -28.4 41.7 -17.1 1.3 58 278 B R E -FE 63 86A 33 28,-1.0 28,-2.2 5,-0.2 2,-0.5 -0.990 51.7-156.8-154.6 137.6 45.1 -17.2 -0.5 59 279 B V E > S-FE 62 85A 2 3,-2.8 3,-2.8 -2,-0.3 2,-0.4 -0.961 74.4 -53.9-118.3 111.2 46.5 -18.1 -3.9 60 280 B N T 3 S- 0 0 26 24,-2.1 23,-0.0 -2,-0.5 16,-0.0 -0.462 123.7 -21.5 54.1-110.8 50.2 -18.9 -3.6 61 281 B E T 3 S+ 0 0 81 -2,-0.4 2,-0.6 -3,-0.1 -1,-0.3 0.454 116.9 105.4 -99.8 -1.7 51.6 -15.9 -1.8 62 282 B V E < -F 59 0A 74 -3,-2.8 -3,-2.8 13,-0.1 2,-0.5 -0.700 64.0-142.1 -90.6 119.4 48.7 -13.6 -2.9 63 283 B D E +F 58 0A 48 -2,-0.6 -5,-0.2 -5,-0.2 3,-0.1 -0.666 24.0 171.9 -80.5 123.7 46.1 -12.7 -0.2 64 284 B V > + 0 0 2 -7,-1.8 3,-0.6 -2,-0.5 -31,-0.5 0.063 43.6 108.3-121.2 22.4 42.6 -12.6 -1.7 65 285 B R T 3 S+ 0 0 32 -8,-0.5 -34,-0.2 1,-0.2 -42,-0.1 0.887 94.8 18.4 -69.0 -41.8 40.5 -12.2 1.5 66 286 B D T 3 S+ 0 0 93 -9,-0.1 -1,-0.2 -3,-0.1 2,-0.2 -0.484 102.5 107.4-131.0 61.9 39.5 -8.5 0.9 67 287 B V < - 0 0 41 -3,-0.6 -43,-2.3 -36,-0.1 -42,-0.2 -0.761 70.0 -79.0-127.7 177.6 40.1 -7.8 -2.8 68 288 B T > - 0 0 41 -2,-0.2 4,-1.8 -45,-0.2 3,-0.4 -0.363 37.2-115.8 -73.8 152.7 38.2 -7.3 -6.0 69 289 B H H > S+ 0 0 11 1,-0.2 4,-2.4 2,-0.2 3,-0.2 0.917 120.0 49.8 -49.6 -46.8 36.7 -10.2 -8.1 70 290 B S H > S+ 0 0 74 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.740 106.8 54.2 -69.2 -26.4 39.1 -9.2 -10.9 71 291 B K H > S+ 0 0 112 -3,-0.4 4,-1.9 2,-0.2 -1,-0.2 0.801 110.3 46.6 -76.9 -31.4 42.1 -9.2 -8.5 72 292 B A H X S+ 0 0 1 -4,-1.8 4,-2.2 2,-0.2 -2,-0.2 0.884 112.7 49.5 -73.0 -42.2 41.2 -12.8 -7.4 73 293 B V H X S+ 0 0 41 -4,-2.4 4,-1.9 2,-0.2 -2,-0.2 0.934 111.6 50.2 -58.4 -46.8 40.8 -13.8 -11.1 74 294 B E H X S+ 0 0 84 -4,-2.2 4,-2.0 1,-0.2 -2,-0.2 0.904 110.0 49.8 -57.1 -46.8 44.2 -12.2 -11.7 75 295 B A H X S+ 0 0 5 -4,-1.9 4,-0.5 1,-0.2 -1,-0.2 0.893 112.7 46.9 -59.5 -42.7 45.8 -14.1 -8.8 76 296 B L H < S+ 0 0 14 -4,-2.2 -1,-0.2 1,-0.2 -2,-0.2 0.787 114.7 45.7 -72.2 -29.6 44.4 -17.4 -10.0 77 297 B K H < S+ 0 0 157 -4,-1.9 3,-0.4 1,-0.2 -1,-0.2 0.790 116.2 44.1 -83.9 -32.5 45.4 -16.9 -13.7 78 298 B E H < S+ 0 0 132 -4,-2.0 -2,-0.2 -5,-0.2 -1,-0.2 0.479 85.1 100.9 -86.3 -6.7 49.0 -15.7 -12.9 79 299 B A S < S- 0 0 16 -4,-0.5 3,-0.2 1,-0.2 2,-0.2 0.574 79.4-130.8 -68.0 -13.4 49.6 -18.4 -10.3 80 300 B G - 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0 0 123 88,-2.0 88,-1.7 2,-0.0 2,-0.5 -0.856 360.0-150.2-104.1 144.7 56.0 -14.9 3.9 94 222 A Y E +H 180 0C 41 -2,-0.4 2,-0.3 86,-0.2 86,-0.2 -0.974 21.2 175.4-120.0 124.0 53.5 -17.3 5.5 95 223 A E E -H 179 0C 46 84,-1.7 84,-2.4 -2,-0.5 2,-0.5 -0.913 23.3-144.3-129.9 148.3 54.6 -19.5 8.4 96 224 A E E -H 178 0C 68 -2,-0.3 2,-0.5 82,-0.2 82,-0.2 -0.975 18.0-176.3-115.2 129.5 53.0 -22.0 10.8 97 225 A I E -H 177 0C 0 80,-2.5 80,-3.1 -2,-0.5 2,-0.5 -0.972 9.4-161.5-130.6 115.2 54.3 -22.2 14.4 98 226 A T E -H 176 0C 50 -2,-0.5 2,-0.4 78,-0.2 78,-0.2 -0.839 16.4-174.8 -93.7 129.7 53.0 -24.7 16.9 99 227 A L E -H 175 0C 4 76,-2.3 76,-2.9 -2,-0.5 2,-0.4 -0.959 22.7-137.2-125.3 143.8 53.8 -23.9 20.6 100 228 A E E -H 174 0C 156 -2,-0.4 2,-0.2 74,-0.2 74,-0.2 -0.849 36.3-111.7 -91.0 134.8 53.3 -25.7 23.9 101 229 A R - 0 0 62 72,-2.7 5,-0.2 -2,-0.4 2,-0.1 -0.497 35.6-152.6 -66.9 129.0 52.0 -23.4 26.6 102 230 A G B > -N 105 0D 32 3,-1.1 3,-1.6 -2,-0.2 5,-0.1 -0.329 34.0 -90.3 -91.4 179.1 54.6 -22.8 29.4 103 231 A N T 3 S+ 0 0 175 1,-0.3 3,-0.1 -2,-0.1 -2,-0.0 0.877 131.5 36.8 -56.4 -41.4 54.1 -22.0 33.1 104 232 A S T > S- 0 0 83 1,-0.4 3,-0.5 2,-0.0 -1,-0.3 -0.186 123.2-105.0-105.2 37.6 54.2 -18.3 32.2 105 233 A G B < -N 102 0D 14 -3,-1.6 -3,-1.1 1,-0.2 30,-0.6 -0.253 65.1 -29.4 79.8-161.2 52.3 -18.7 28.9 106 234 A L T 3 S- 0 0 0 441,-2.2 30,-2.0 -5,-0.2 -1,-0.2 0.648 77.9-121.9 -72.5 -18.8 53.4 -18.5 25.3 107 235 A G S < S+ 0 0 3 -3,-0.5 24,-2.7 1,-0.3 2,-0.3 0.771 74.0 91.7 82.9 28.4 56.3 -16.1 26.0 108 236 A F E -I 130 0C 0 22,-0.2 439,-3.1 28,-0.1 2,-0.3 -0.973 60.4-133.3-146.6 163.9 55.4 -13.3 23.7 109 237 A S E -IJ 129 546C 14 20,-2.4 19,-2.0 -2,-0.3 20,-0.8 -0.900 15.7-151.5-118.0 147.7 53.5 -10.0 23.6 110 238 A I E +IJ 127 545C 0 435,-2.5 435,-1.9 -2,-0.3 2,-0.3 -0.955 12.4 178.7-122.0 137.4 51.0 -8.7 21.1 111 239 A A E +IJ 126 544C 0 15,-2.5 15,-2.9 -2,-0.4 2,-0.2 -0.778 44.5 59.2-116.5 170.9 50.0 -5.2 20.0 112 240 A G + 0 0 7 431,-0.5 13,-0.3 -2,-0.3 12,-0.2 -0.576 37.5 147.6 107.4-169.5 47.5 -4.3 17.3 113 241 A G > - 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