==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=11-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER GROWTH FACTOR/GROWTH FACTOR RECEPTOR 19-DEC-03 1RY7 . COMPND 2 MOLECULE: HEPARIN-BINDING GROWTH FACTOR 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.K.OLSEN,O.A.IBRAHIMI,A.RAUCCI,F.ZHANG,A.V.ELISEENKOVA, . 364 2 1 1 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 18492.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 203 55.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 11 3.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 76 20.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 48 13.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 35 9.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 8 2.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 8 6 2 1 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 5 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 5 A E 0 0 146 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 111.9 2.7 -25.7 41.8 2 6 A I + 0 0 165 1,-0.0 2,-0.3 0, 0.0 0, 0.0 0.024 360.0 140.1 -63.2-177.8 5.4 -26.2 39.2 3 7 A T - 0 0 88 5,-0.0 2,-0.2 0, 0.0 5,-0.1 -0.891 34.6-127.1 161.2-174.1 9.0 -25.0 39.9 4 8 A T - 0 0 92 3,-0.7 0, 0.0 1,-0.3 0, 0.0 -0.789 24.8 -86.3-146.2-172.0 12.4 -26.5 39.2 5 9 A F S S+ 0 0 162 -2,-0.2 2,-0.7 3,-0.1 -1,-0.3 0.232 106.1 50.5 -77.0-145.4 15.7 -27.5 40.7 6 10 A T S >> S+ 0 0 89 2,-0.1 3,-4.1 1,-0.1 4,-2.6 -0.337 113.4 49.5 50.0-100.3 18.3 -24.7 40.8 7 11 A A T 34 S+ 0 0 40 -2,-0.7 -3,-0.7 1,-0.3 -1,-0.1 -0.498 110.2 50.8 -66.7 94.4 15.8 -22.4 42.5 8 12 A L T 34 S+ 0 0 121 -2,-1.6 -1,-0.3 -5,-0.1 -2,-0.1 -0.117 122.9 30.8 161.6 -28.8 14.9 -25.0 45.0 9 13 A T T <4 S+ 0 0 96 -3,-4.1 -2,-0.2 0, 0.0 -3,-0.1 0.408 96.6 116.2-122.8 -14.8 18.5 -25.6 45.9 10 14 A E < - 0 0 86 -4,-2.6 3,-0.1 1,-0.1 -3,-0.0 0.100 56.4-150.3 -50.6 169.8 19.8 -22.1 45.2 11 15 A K S S+ 0 0 179 1,-0.5 249,-0.3 -4,-0.0 2,-0.3 0.285 88.1 27.1-125.3 1.5 21.2 -19.9 48.0 12 16 A F - 0 0 21 247,-0.1 -1,-0.5 268,-0.0 268,-0.0 -0.898 66.7-151.1-163.4 130.4 20.0 -16.7 46.4 13 17 A N S S+ 0 0 124 -2,-0.3 -6,-0.0 -3,-0.1 -3,-0.0 0.049 74.3 72.5-101.1 27.4 17.1 -16.3 44.0 14 18 A L S S- 0 0 48 243,-0.0 245,-0.1 267,-0.0 266,-0.1 -0.977 96.8 -89.7-136.4 149.3 18.4 -13.4 42.0 15 19 A P > - 0 0 68 0, 0.0 3,-1.1 0, 0.0 267,-0.2 -0.391 50.3-129.3 -58.4 118.9 21.2 -13.2 39.4 16 20 A P T 3 S+ 0 0 47 0, 0.0 308,-0.2 0, 0.0 265,-0.1 -0.452 82.5 2.8 -74.5 148.4 24.3 -12.5 41.5 17 21 A G T >> S+ 0 0 3 263,-0.4 3,-2.2 1,-0.1 4,-0.6 0.737 79.7 154.6 50.8 28.5 26.5 -9.6 40.4 18 22 A N T <4 + 0 0 48 -3,-1.1 -1,-0.1 262,-0.3 263,-0.1 0.580 63.7 64.8 -62.0 -10.5 24.1 -8.8 37.7 19 23 A Y T 34 S+ 0 0 13 261,-0.3 -1,-0.3 1,-0.2 38,-0.2 0.608 92.8 62.7 -87.6 -13.0 25.2 -5.1 37.7 20 24 A K T <4 S+ 0 0 44 -3,-2.2 -2,-0.2 302,-0.2 -1,-0.2 0.783 88.4 82.3 -79.7 -31.3 28.7 -6.2 36.5 21 25 A K S < S- 0 0 49 -4,-0.6 36,-0.3 1,-0.1 2,-0.2 -0.389 86.0-112.8 -72.6 153.3 27.4 -7.6 33.2 22 26 A P - 0 0 45 0, 0.0 126,-0.4 0, 0.0 2,-0.3 -0.564 34.9-179.3 -91.4 157.5 26.8 -5.2 30.3 23 27 A K E -A 55 0A 36 32,-2.7 32,-2.0 -2,-0.2 2,-0.3 -0.884 29.1 -97.1-145.1 174.1 23.5 -4.1 28.8 24 28 A L E -AB 54 146A 0 122,-2.7 122,-1.8 -2,-0.3 2,-0.7 -0.682 26.2-136.8 -96.0 149.6 21.9 -2.0 26.2 25 29 A L E - B 0 145A 0 28,-0.5 9,-1.6 9,-0.3 29,-0.0 -0.640 25.4-167.5-109.9 75.2 20.4 1.4 27.0 26 30 A Y - 0 0 3 118,-0.8 2,-0.3 -2,-0.7 118,-0.2 0.232 12.5-135.4 -44.6 177.5 17.1 1.7 25.1 27 31 A C - 0 0 0 5,-0.5 5,-0.3 116,-0.2 116,-0.3 -0.793 5.6-146.9-151.1 104.1 15.3 5.0 24.8 28 32 A S S S+ 0 0 10 114,-3.1 112,-0.2 -2,-0.3 115,-0.1 0.649 94.8 64.6 -41.0 -23.9 11.6 5.4 25.4 29 33 A N S S- 0 0 23 110,-0.7 -1,-0.2 111,-0.2 111,-0.1 0.999 120.6 -3.5 -68.5 -73.7 11.5 8.1 22.7 30 34 A G S S- 0 0 0 -3,-0.2 94,-0.1 92,-0.2 95,-0.1 0.694 89.0 -99.3 -85.8-109.6 12.5 6.2 19.5 31 35 A G S S+ 0 0 0 93,-0.1 -3,-0.1 136,-0.1 134,-0.1 0.087 74.8 136.7-163.2 12.8 13.4 2.6 19.7 32 36 A H - 0 0 5 -5,-0.3 2,-0.6 -6,-0.1 -5,-0.5 -0.148 54.1-134.4 -74.3 162.5 17.1 3.1 19.7 33 37 A F - 0 0 0 12,-1.8 -7,-0.2 -7,-0.2 10,-0.1 -0.973 42.9-106.0-116.2 108.7 19.9 1.6 21.6 34 38 A L - 0 0 0 -9,-1.6 2,-0.4 -2,-0.6 -9,-0.3 -0.018 44.3-158.8 -34.3 135.6 22.2 4.4 22.7 35 39 A R E -D 43 0B 60 8,-2.2 8,-2.4 18,-0.0 2,-0.8 -0.988 24.1-163.1-133.8 129.9 25.3 4.2 20.5 36 40 A I E -D 42 0B 0 16,-1.4 6,-0.3 -2,-0.4 38,-0.1 -0.728 32.7-138.5-108.8 78.9 28.8 5.5 21.0 37 41 A L > - 0 0 32 4,-1.5 3,-1.3 -2,-0.8 -2,-0.0 0.041 19.1-111.8 -37.2 134.9 30.1 5.3 17.4 38 42 A P T 3 S+ 0 0 74 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.826 120.2 56.2 -39.7 -45.1 33.7 4.1 17.1 39 43 A D T 3 S- 0 0 115 2,-0.1 -2,-0.1 1,-0.1 47,-0.1 0.928 126.3-103.3 -56.7 -45.2 34.8 7.5 16.0 40 44 A G S < S+ 0 0 13 -3,-1.3 2,-0.2 1,-0.4 -1,-0.1 0.293 80.0 118.9 140.6 -11.1 33.4 8.9 19.2 41 45 A T - 0 0 72 -5,-0.1 -4,-1.5 45,-0.1 -1,-0.4 -0.522 52.8-132.9 -83.8 155.5 30.0 10.5 18.5 42 46 A V E +D 36 0B 10 42,-0.9 86,-0.6 -6,-0.3 2,-0.3 -0.819 35.8 134.6-111.6 148.5 26.8 9.2 20.1 43 47 A D E -DE 35 127B 26 -8,-2.4 -8,-2.2 -2,-0.3 84,-0.2 -0.959 43.0 -78.9-168.6-175.1 23.4 8.4 18.6 44 48 A G + 0 0 5 82,-3.5 2,-0.2 -2,-0.3 -10,-0.1 -0.363 36.3 163.2 -96.8 176.9 20.4 6.1 18.3 45 49 A T - 0 0 16 -2,-0.1 -12,-1.8 1,-0.1 81,-0.0 -0.816 34.3-150.9 173.2 146.1 19.7 2.9 16.4 46 50 A R + 0 0 90 -2,-0.2 2,-1.2 -14,-0.2 -1,-0.1 0.632 61.2 120.4-101.1 -19.5 17.3 -0.0 16.3 47 51 A D > - 0 0 85 1,-0.2 3,-3.5 2,-0.1 -14,-0.0 -0.234 51.8-160.0 -51.1 88.3 19.9 -2.4 14.8 48 52 A R T 3 S+ 0 0 69 -2,-1.2 -1,-0.2 1,-0.3 5,-0.0 0.354 91.2 55.8 -56.1 11.6 19.8 -5.0 17.6 49 53 A S T 3 + 0 0 79 3,-0.0 -1,-0.3 4,-0.0 2,-0.1 0.520 68.6 132.4-119.3 -15.3 23.2 -5.9 16.2 50 54 A D X - 0 0 10 -3,-3.5 3,-0.9 1,-0.2 4,-0.3 -0.171 54.2-143.5 -44.9 106.2 25.0 -2.6 16.3 51 55 A Q T 3 S+ 0 0 45 1,-0.3 -1,-0.2 2,-0.1 20,-0.1 0.311 92.0 62.3 -60.3 13.6 28.3 -3.5 17.9 52 56 A H T 3 S+ 0 0 39 -2,-0.2 -16,-1.4 19,-0.1 -1,-0.3 -0.116 80.8 73.5-134.7 40.3 28.3 -0.2 19.8 53 57 A I < + 0 0 1 -3,-0.9 2,-1.7 -18,-0.2 -28,-0.5 0.395 62.7 108.5-124.8 -10.3 25.2 -0.4 22.0 54 58 A Q E -A 24 0A 33 -4,-0.3 16,-2.4 -30,-0.1 17,-0.3 -0.543 55.2-171.5 -74.7 88.2 26.6 -2.9 24.5 55 59 A L E -AC 23 69A 2 -32,-2.0 -32,-2.7 -2,-1.7 2,-0.5 -0.597 17.6-157.6 -88.7 145.1 27.1 -0.5 27.5 56 60 A Q - 0 0 52 12,-3.0 2,-0.1 -34,-0.2 -36,-0.1 -0.938 18.0-167.3-122.9 102.0 28.9 -1.5 30.7 57 61 A L + 0 0 3 -2,-0.5 2,-0.3 -36,-0.3 10,-0.2 -0.280 12.1 166.2 -86.7 171.8 27.9 0.7 33.6 58 62 A S B -G 66 0C 48 8,-0.9 8,-2.7 -2,-0.1 2,-0.4 -0.919 24.1-135.0-176.8 157.1 29.5 1.1 37.1 59 63 A A - 0 0 17 227,-0.4 6,-0.2 -2,-0.3 3,-0.1 -0.979 13.2-174.5-132.6 124.2 29.3 3.5 40.1 60 64 A E S S+ 0 0 133 -2,-0.4 2,-0.3 4,-0.2 5,-0.1 0.598 87.6 12.5 -86.4 -11.9 32.2 4.9 42.0 61 65 A S S S- 0 0 47 3,-0.8 3,-0.4 225,-0.1 -1,-0.2 -0.966 105.7 -65.0-155.8 160.7 29.7 6.3 44.4 62 66 A V S S- 0 0 52 -2,-0.3 2,-1.3 1,-0.2 3,-0.1 -0.212 115.5 -5.6 -51.5 132.2 25.9 6.0 45.1 63 67 A G S S+ 0 0 14 222,-0.5 35,-3.0 1,-0.1 2,-0.4 -0.041 108.2 103.4 76.0 -39.6 23.8 7.1 42.2 64 68 A E E +H 97 0D 47 -2,-1.3 -3,-0.8 -3,-0.4 2,-0.3 -0.656 52.0 175.0 -80.0 132.5 26.7 8.4 40.1 65 69 A V E -H 96 0D 0 31,-2.9 31,-2.4 -2,-0.4 2,-0.4 -0.974 31.3-132.1-143.5 157.3 27.6 6.2 37.3 66 70 A Y B -G 58 0C 29 -8,-2.7 -8,-0.9 -2,-0.3 2,-0.5 -0.828 17.8-150.7-101.8 139.3 29.8 5.7 34.2 67 71 A I + 0 0 0 27,-0.4 2,-0.3 -2,-0.4 9,-0.3 -0.957 28.5 169.3-111.7 131.2 28.3 4.6 30.9 68 72 A K - 0 0 63 -2,-0.5 -12,-3.0 7,-0.2 2,-0.3 -0.954 32.0-116.1-142.9 160.9 30.7 2.6 28.8 69 73 A S B -C 55 0A 4 5,-0.4 -14,-0.2 -2,-0.3 -17,-0.1 -0.731 9.4-147.8 -98.5 147.1 31.0 0.4 25.7 70 74 A T S S+ 0 0 73 -16,-2.4 -15,-0.1 -2,-0.3 -1,-0.1 0.572 96.1 52.9 -86.8 -9.6 32.1 -3.2 25.7 71 75 A E S S+ 0 0 119 -17,-0.3 -1,-0.1 -20,-0.1 -19,-0.1 0.918 125.7 5.3 -89.4 -54.9 33.8 -2.9 22.3 72 76 A T S S- 0 0 70 2,-0.1 -20,-0.0 0, 0.0 -4,-0.0 0.794 85.3-113.9 -93.1 -94.5 36.1 0.1 22.7 73 77 A G + 0 0 27 14,-0.1 2,-0.8 13,-0.1 -3,-0.1 0.248 50.8 158.9 155.1 35.3 36.4 1.7 26.1 74 78 A Q - 0 0 4 -38,-0.1 2,-2.4 1,-0.1 -5,-0.4 -0.743 36.0-145.0 -88.1 110.1 34.9 5.1 25.5 75 79 A Y - 0 0 53 12,-1.6 12,-0.5 -2,-0.8 16,-0.2 -0.397 29.4-131.2 -73.4 65.8 33.7 6.7 28.8 76 80 A L + 0 0 0 -2,-2.4 -9,-0.4 10,-0.3 2,-0.3 0.343 38.3 171.2 -15.8 134.0 30.6 8.4 27.3 77 81 A A - 0 0 0 8,-0.1 8,-2.8 -11,-0.1 2,-0.4 -0.918 33.9-121.8-150.7 176.1 30.4 12.1 28.3 78 82 A M E -L 84 0E 0 15,-2.3 6,-0.3 -2,-0.3 17,-0.1 -0.985 25.8-143.2-128.3 122.1 28.7 15.5 27.9 79 83 A D E >> -L 83 0E 24 4,-3.0 3,-2.9 -2,-0.4 4,-0.5 -0.398 36.8 -94.3 -82.2 159.4 30.6 18.6 26.9 80 84 A T T 34 S+ 0 0 94 1,-0.3 -1,-0.1 2,-0.2 -2,-0.0 0.631 125.9 59.2 -45.6 -16.4 30.0 22.1 28.1 81 85 A D T 34 S- 0 0 82 2,-0.1 -1,-0.3 50,-0.0 3,-0.1 0.778 122.9-102.8 -85.4 -29.0 27.7 22.6 25.0 82 86 A G T <4 S+ 0 0 0 -3,-2.9 49,-2.3 1,-0.3 2,-0.5 0.564 74.8 143.5 111.6 21.5 25.4 19.7 26.0 83 87 A L E < -L 79 0E 67 -4,-0.5 -4,-3.0 47,-0.2 2,-0.6 -0.822 45.7-139.7 -98.7 127.0 26.9 17.3 23.5 84 88 A L E +L 78 0E 8 -2,-0.5 -42,-0.9 -6,-0.3 -6,-0.3 -0.740 39.6 148.3 -85.7 121.9 27.3 13.7 24.3 85 89 A Y - 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