==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=11-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE(OXO-ACID) 25-MAY-93 1RZC . COMPND 2 MOLECULE: CARBONIC ANHYDRASE II; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR K.HAKANSSON,A.WEHNERT,A.LILJAS . 258 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11845.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 165 64.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 19 7.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 57 22.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 23 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 34 13.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 17 6.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 2 2 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A H 0 0 230 0, 0.0 2,-0.2 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0-135.6 13.6 -0.6 8.8 2 4 A H - 0 0 129 1,-0.1 2,-0.0 0, 0.0 0, 0.0 -0.486 360.0 -98.5 -87.0 150.0 9.9 0.2 9.0 3 5 A W + 0 0 37 -2,-0.2 2,-0.2 1,-0.1 7,-0.2 -0.246 57.1 133.6 -59.2 146.4 7.6 -1.5 11.4 4 6 A G - 0 0 10 5,-2.4 10,-0.1 2,-0.2 -1,-0.1 -0.769 64.5 -83.0-163.4-147.5 5.4 -4.4 10.4 5 7 A Y S S+ 0 0 32 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.264 83.1 109.6-123.9 12.9 4.4 -7.8 11.7 6 8 A G S > S- 0 0 38 4,-0.1 4,-1.6 1,-0.1 -2,-0.2 -0.183 84.7 -94.8 -82.2 178.5 7.3 -9.9 10.3 7 9 A K T 4 S+ 0 0 145 1,-0.2 -1,-0.1 2,-0.2 5,-0.1 0.836 123.2 39.7 -61.9 -34.8 10.1 -11.6 12.2 8 10 A H T 4 S+ 0 0 163 1,-0.1 -1,-0.2 4,-0.0 -5,-0.0 0.723 129.8 24.4 -93.8 -20.1 12.5 -8.7 11.6 9 11 A N T 4 S+ 0 0 56 -3,-0.1 -5,-2.4 -6,-0.1 -2,-0.2 0.259 95.7 129.9-126.4 14.7 10.2 -5.6 12.1 10 12 A G S >X S- 0 0 0 -4,-1.6 3,-2.4 -7,-0.2 4,-0.7 0.156 77.8 -78.2 -65.8 176.6 7.5 -7.2 14.3 11 13 A P G >4 S+ 0 0 26 0, 0.0 3,-0.6 0, 0.0 4,-0.4 0.720 125.6 61.8 -53.1 -28.8 5.9 -6.1 17.6 12 14 A E G 34 S+ 0 0 100 1,-0.2 3,-0.1 2,-0.1 -2,-0.1 0.607 107.7 46.9 -73.5 -14.3 9.0 -7.3 19.6 13 15 A H G X4 S+ 0 0 47 -3,-2.4 3,-1.6 1,-0.1 4,-0.5 0.620 85.1 89.8 -96.4 -20.6 11.0 -4.8 17.8 14 16 A W G XX S+ 0 0 5 -4,-0.7 4,-2.7 -3,-0.6 3,-1.2 0.792 73.6 70.0 -52.6 -41.9 8.7 -1.7 18.0 15 17 A H G 34 S+ 0 0 66 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.762 88.0 66.0 -47.8 -33.7 10.2 -0.4 21.2 16 18 A K G <4 S+ 0 0 135 -3,-1.6 -1,-0.2 1,-0.2 -2,-0.2 0.842 118.6 23.2 -63.8 -33.4 13.5 0.6 19.4 17 19 A D T <4 S+ 0 0 112 -3,-1.2 -2,-0.2 -4,-0.5 -1,-0.2 0.733 136.0 35.9-103.0 -24.5 11.7 3.2 17.4 18 20 A F >< - 0 0 63 -4,-2.7 3,-3.1 1,-0.1 -1,-0.2 -0.804 63.9-176.5-133.1 82.6 8.7 3.8 19.8 19 21 A P G > S+ 0 0 99 0, 0.0 3,-1.9 0, 0.0 -4,-0.1 0.738 78.3 76.8 -54.1 -24.5 10.0 3.5 23.4 20 22 A I G > + 0 0 54 1,-0.3 3,-2.7 2,-0.1 -5,-0.1 0.734 68.7 88.7 -61.6 -16.8 6.4 4.0 24.4 21 23 A A G < S+ 0 0 8 -3,-3.1 -1,-0.3 1,-0.3 -6,-0.1 0.724 91.3 45.5 -48.1 -31.3 5.9 0.4 23.4 22 24 A K G < S+ 0 0 135 -3,-1.9 -1,-0.3 -4,-0.2 -2,-0.1 -0.014 91.8 132.3-103.1 27.3 6.9 -0.5 27.0 23 25 A G < - 0 0 16 -3,-2.7 3,-0.4 1,-0.1 -3,-0.0 -0.003 69.9-107.3 -69.5 179.8 4.7 2.2 28.6 24 26 A E S S+ 0 0 116 1,-0.2 226,-0.3 225,-0.1 -1,-0.1 0.477 112.3 43.6 -89.3 -10.9 2.4 1.8 31.5 25 27 A R S S+ 0 0 47 224,-0.1 -1,-0.2 2,-0.0 2,-0.1 -0.303 79.4 151.1-135.1 50.2 -0.9 2.0 29.5 26 28 A Q - 0 0 3 -3,-0.4 220,-0.1 221,-0.3 170,-0.1 -0.443 34.7-104.2 -82.7 143.6 -0.2 -0.2 26.5 27 29 A S S S+ 0 0 0 168,-0.4 2,-0.2 -2,-0.1 -2,-0.0 -0.883 76.1 41.6-121.1 158.2 -2.8 -2.1 24.5 28 30 A P + 0 0 0 0, 0.0 218,-2.6 0, 0.0 2,-0.3 0.650 64.7 178.2 -77.4 177.3 -4.1 -4.8 23.9 29 31 A V - 0 0 1 216,-0.3 77,-1.3 -2,-0.2 2,-0.5 -0.882 35.9-101.2-131.3 167.1 -4.5 -6.7 27.1 30 32 A D E -a 106 0A 35 216,-0.4 2,-0.8 -2,-0.3 77,-0.2 -0.778 35.4-136.4 -88.5 129.1 -6.0 -10.1 28.2 31 33 A I E -a 107 0A 0 75,-3.2 77,-3.4 -2,-0.5 2,-0.8 -0.840 12.8-158.4 -94.0 110.5 -9.5 -9.5 29.8 32 34 A D >> - 0 0 63 -2,-0.8 4,-1.1 75,-0.2 3,-1.0 -0.819 3.9-159.6 -88.4 102.9 -9.7 -11.7 32.9 33 35 A T T 34 S+ 0 0 48 -2,-0.8 -1,-0.1 1,-0.3 74,-0.0 0.699 86.3 52.4 -63.9 -23.2 -13.4 -11.9 33.4 34 36 A H T 34 S+ 0 0 159 1,-0.2 -1,-0.3 -3,-0.0 -2,-0.0 0.642 112.8 45.2 -88.9 -12.9 -13.3 -12.9 37.0 35 37 A T T <4 S+ 0 0 107 -3,-1.0 2,-0.3 2,-0.1 218,-0.2 0.524 85.6 103.2-106.4 -9.5 -11.1 -9.9 37.9 36 38 A A S < S- 0 0 19 -4,-1.1 2,-0.5 216,-0.1 218,-0.2 -0.568 71.6-130.5 -72.4 136.5 -13.0 -7.2 36.0 37 39 A K E -c 254 0B 116 216,-2.1 218,-3.1 -2,-0.3 2,-0.4 -0.777 9.9-128.1 -92.5 128.7 -15.1 -5.1 38.4 38 40 A Y E -c 255 0B 86 -2,-0.5 218,-0.2 216,-0.2 220,-0.1 -0.607 25.2-162.2 -72.8 130.7 -18.8 -4.5 37.6 39 41 A D > - 0 0 25 216,-2.6 3,-1.8 -2,-0.4 -1,-0.0 -0.913 13.2-169.5-122.9 108.3 -19.2 -0.7 37.8 40 42 A P T 3 S+ 0 0 97 0, 0.0 -1,-0.1 0, 0.0 216,-0.1 0.592 83.5 69.4 -70.2 -12.9 -22.9 0.4 38.2 41 43 A S T 3 S+ 0 0 83 2,-0.1 2,-0.4 40,-0.0 215,-0.1 0.467 75.0 103.8 -85.0 -4.9 -22.0 4.0 37.6 42 44 A L < - 0 0 27 -3,-1.8 3,-0.1 213,-0.2 -3,-0.0 -0.697 66.8-143.9 -80.1 132.1 -21.1 3.2 33.9 43 45 A K - 0 0 113 37,-1.2 39,-0.1 -2,-0.4 2,-0.1 -0.430 29.2 -86.9 -88.7 164.3 -23.9 4.4 31.7 44 46 A P - 0 0 113 0, 0.0 36,-1.3 0, 0.0 -1,-0.1 -0.429 49.5-103.7 -68.3 148.9 -25.1 2.5 28.5 45 47 A L E -D 79 0B 16 141,-0.3 2,-0.5 34,-0.3 34,-0.2 -0.437 27.4-148.5 -69.2 150.5 -23.2 3.3 25.4 46 48 A S E -D 78 0B 50 32,-2.5 32,-2.2 -2,-0.1 2,-0.5 -0.969 14.8-176.5-130.0 106.9 -24.9 5.6 22.8 47 49 A V E -D 77 0B 33 -2,-0.5 2,-0.5 30,-0.2 30,-0.2 -0.963 3.2-178.6-101.7 117.2 -23.9 4.8 19.2 48 50 A S E +D 76 0B 35 28,-3.0 28,-2.1 -2,-0.5 3,-0.2 -0.868 25.1 141.7-121.0 94.1 -25.5 7.2 16.6 49 51 A Y > + 0 0 3 -2,-0.5 3,-1.3 26,-0.2 130,-0.3 0.118 35.7 106.8-113.7 11.6 -24.3 6.1 13.2 50 52 A D T 3 S+ 0 0 101 1,-0.3 -1,-0.1 128,-0.1 25,-0.1 0.815 85.7 44.4 -66.1 -22.5 -27.6 6.7 11.3 51 53 A Q T 3 S+ 0 0 126 23,-0.8 -1,-0.3 -3,-0.2 24,-0.2 0.319 84.1 147.0-103.1 10.4 -26.0 9.8 9.6 52 54 A A < - 0 0 21 -3,-1.3 2,-0.5 22,-0.2 123,-0.1 -0.025 31.6-162.3 -49.9 134.9 -22.7 8.1 8.8 53 55 A T - 0 0 48 16,-0.3 16,-2.7 122,-0.1 2,-0.2 -0.877 4.3-165.9-121.7 101.7 -20.9 9.1 5.6 54 56 A S E +E 68 0B 1 -2,-0.5 121,-0.7 122,-0.3 14,-0.3 -0.590 11.1 173.8 -84.7 154.2 -18.2 6.7 4.4 55 57 A L E - 0 0 81 12,-3.4 118,-1.9 1,-0.4 2,-0.3 0.702 50.8 -2.1-119.4 -44.8 -15.9 8.0 1.8 56 58 A R E -EF 67 172B 90 11,-1.1 11,-3.1 116,-0.3 2,-0.4 -0.979 43.4-140.3-156.6 158.7 -13.1 5.6 1.0 57 59 A I E -EF 66 171B 0 114,-2.4 114,-2.3 -2,-0.3 2,-0.4 -0.984 29.0-174.6-127.1 135.3 -11.3 2.3 1.7 58 60 A L E -EF 65 170B 30 7,-2.3 7,-2.6 -2,-0.4 2,-0.8 -0.997 28.2-142.5-138.3 141.1 -7.5 2.2 1.7 59 61 A N E +E 64 0B 0 110,-2.7 109,-3.1 -2,-0.4 5,-0.2 -0.832 22.3 178.4 -96.2 112.7 -4.8 -0.4 2.0 60 62 A N - 0 0 46 3,-1.7 -1,-0.1 -2,-0.8 4,-0.1 0.297 55.0 -99.5-100.6 5.5 -2.1 1.3 4.1 61 63 A G S S+ 0 0 16 2,-0.5 106,-0.1 166,-0.2 3,-0.1 0.377 116.8 55.1 92.3 -5.4 0.2 -1.6 4.1 62 64 A H S S- 0 0 43 1,-0.6 2,-0.3 -58,-0.1 166,-0.1 0.556 122.9 -26.9-131.0 -18.6 -0.7 -2.8 7.6 63 65 A A S S- 0 0 0 -5,-0.1 -3,-1.7 164,-0.1 -1,-0.6 -0.830 71.7 -91.2-169.0-167.7 -4.5 -3.2 7.4 64 66 A F E -E 59 0B 0 29,-0.3 29,-0.5 -2,-0.3 2,-0.4 -0.986 36.2-156.4-124.0 131.5 -7.4 -1.7 5.3 65 67 A N E -EG 58 92B 18 -7,-2.6 -7,-2.3 -2,-0.4 2,-0.5 -0.953 9.0-153.0-109.8 135.7 -9.2 1.4 6.7 66 68 A V E -EG 57 91B 0 25,-2.3 25,-1.6 -2,-0.4 2,-0.3 -0.950 26.9-150.2 -99.8 129.0 -12.7 2.5 5.8 67 69 A E E -EG 56 90B 46 -11,-3.1 -12,-3.4 -2,-0.5 -11,-1.1 -0.783 10.5-159.5-109.7 146.0 -12.8 6.3 6.3 68 70 A F E -E 54 0B 7 21,-2.3 2,-0.7 -2,-0.3 -14,-0.2 -0.787 31.7-102.5-116.7 152.8 -15.7 8.5 7.2 69 71 A D + 0 0 37 -16,-2.7 -16,-0.3 -2,-0.3 6,-0.3 -0.759 38.6 175.9 -75.4 117.0 -16.3 12.2 6.9 70 72 A D + 0 0 41 -2,-0.7 -1,-0.1 1,-0.1 17,-0.1 -0.090 45.7 111.8-112.7 26.6 -15.7 13.5 10.4 71 73 A S S S+ 0 0 77 2,-0.0 2,-0.3 0, 0.0 -1,-0.1 0.551 87.1 14.2 -77.3 -9.3 -16.2 17.2 9.5 72 74 A Q S S- 0 0 114 -3,-0.2 2,-2.2 3,-0.0 3,-0.4 -0.919 100.5 -78.2-153.8 169.1 -19.3 17.3 11.6 73 75 A D S S+ 0 0 89 -2,-0.3 3,-0.2 1,-0.2 -3,-0.1 -0.450 78.9 127.4 -73.7 66.9 -21.1 15.3 14.2 74 76 A K S S+ 0 0 52 -2,-2.2 -23,-0.8 1,-0.3 2,-0.6 0.917 74.8 23.2 -87.9 -58.0 -22.5 12.7 11.7 75 77 A A S S+ 0 0 6 -3,-0.4 13,-3.2 -6,-0.3 2,-0.3 -0.956 86.5 166.8-116.6 106.3 -21.4 9.3 13.3 76 78 A V E -DH 48 87B 8 -28,-2.1 -28,-3.0 -2,-0.6 2,-0.4 -0.860 29.8-153.7-126.6 161.7 -20.8 9.7 17.0 77 79 A L E +DH 47 86B 0 9,-3.1 9,-2.2 -2,-0.3 2,-0.3 -0.974 28.2 148.0-127.3 140.1 -20.2 7.7 20.2 78 80 A K E +D 46 0B 71 -32,-2.2 -32,-2.5 -2,-0.4 7,-0.1 -0.914 36.4 46.9-158.7 179.2 -21.1 9.0 23.7 79 81 A G E > S+D 45 0B 22 5,-0.3 3,-2.2 3,-0.3 -34,-0.3 -0.303 71.9 84.8 76.5-161.6 -22.2 7.7 27.1 80 82 A G T 3 S- 0 0 0 -36,-1.3 -37,-1.2 1,-0.3 -1,-0.1 -0.512 122.0 -28.3 66.1-138.6 -20.5 4.6 28.6 81 83 A P T 3 S+ 0 0 39 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.239 115.9 112.1 -89.9 7.6 -17.4 5.8 30.4 82 84 A L < - 0 0 11 -3,-2.2 2,-0.5 -39,-0.1 -3,-0.3 -0.565 52.3-157.1 -88.9 151.1 -17.0 8.8 28.1 83 85 A D + 0 0 128 -2,-0.2 2,-0.1 53,-0.1 -3,-0.0 -0.990 67.9 2.3-117.1 126.3 -17.4 12.5 28.7 84 86 A G S S- 0 0 45 -2,-0.5 2,-0.4 38,-0.1 -5,-0.3 -0.345 98.1 -51.7 93.1 177.4 -18.2 14.5 25.5 85 87 A T - 0 0 29 -7,-0.1 38,-3.0 -2,-0.1 2,-0.5 -0.855 40.0-160.9-106.2 134.5 -18.7 13.5 22.0 86 88 A Y E -HI 77 122B 5 -9,-2.2 -9,-3.1 -2,-0.4 2,-0.4 -0.963 11.3-146.8-119.0 123.8 -16.5 11.3 19.9 87 89 A R E -HI 76 121B 46 34,-2.1 34,-2.1 -2,-0.5 -11,-0.2 -0.774 20.4-117.3 -91.6 134.3 -16.8 11.3 16.1 88 90 A L E + I 0 120B 2 -13,-3.2 32,-0.3 -2,-0.4 -13,-0.2 -0.486 38.4 166.3 -69.3 130.3 -16.1 8.2 14.0 89 91 A I E - 0 0 33 30,-2.6 -21,-2.3 1,-0.4 2,-0.3 0.684 60.1 -19.8-111.8 -42.3 -13.1 8.7 11.7 90 92 A Q E -GI 67 119B 32 29,-1.3 29,-2.9 -23,-0.2 -1,-0.4 -0.982 47.4-148.9-160.5 160.7 -12.2 5.2 10.5 91 93 A F E +GI 66 118B 0 -25,-1.6 -25,-2.3 -2,-0.3 2,-0.3 -0.959 21.4 166.4-130.9 155.0 -12.6 1.4 11.2 92 94 A H E -GI 65 117B 23 25,-1.8 25,-3.2 -2,-0.3 2,-0.3 -0.946 24.3-122.8-154.5 172.5 -10.2 -1.4 10.4 93 95 A F E - I 0 116B 0 -29,-0.5 2,-0.4 -2,-0.3 -29,-0.3 -0.881 2.8-150.8-120.9 161.3 -9.6 -5.0 11.3 94 96 A H E + I 0 115B 1 21,-2.3 21,-2.6 -2,-0.3 2,-0.3 -0.968 33.1 167.5-124.5 130.9 -6.9 -7.2 12.9 95 97 A W E - I 0 114B 0 -2,-0.4 146,-1.2 19,-0.2 145,-0.7 -0.929 23.9-122.7-146.7 170.1 -6.9 -10.9 11.7 96 98 A G - 0 0 0 17,-1.3 6,-0.1 5,-0.6 3,-0.1 -0.493 24.3-119.9-112.8-180.0 -5.0 -14.1 11.6 97 99 A S S S+ 0 0 44 -2,-0.2 2,-0.3 142,-0.1 5,-0.1 0.594 103.8 31.6 -88.5 -16.6 -3.5 -16.6 9.3 98 100 A L S > S- 0 0 109 3,-0.2 3,-1.9 15,-0.1 -2,-0.2 -0.940 88.9-109.9-136.3 157.3 -5.8 -19.3 10.9 99 101 A D T 3 S+ 0 0 72 -2,-0.3 48,-0.2 1,-0.3 15,-0.1 0.761 110.0 68.3 -64.1 -18.3 -9.1 -19.2 12.6 100 102 A G T 3 S+ 0 0 57 13,-0.1 2,-0.3 2,-0.1 11,-0.3 0.449 106.7 28.6 -83.3 2.8 -7.6 -19.7 16.0 101 103 A Q < + 0 0 54 -3,-1.9 -5,-0.6 12,-0.1 -3,-0.2 -0.945 64.1 99.4-151.8 167.4 -5.9 -16.4 16.2 102 104 A G + 0 0 1 1,-0.5 13,-0.3 -2,-0.3 11,-0.2 0.029 55.3 106.4 140.3 -31.3 -6.2 -12.8 14.9 103 105 A S - 0 0 2 9,-1.8 -1,-0.5 11,-0.3 12,-0.1 -0.324 52.9-152.8 -74.6 163.0 -7.8 -10.8 17.8 104 106 A E S S+ 0 0 2 -10,-0.1 -1,-0.1 -3,-0.1 141,-0.1 0.872 82.9 53.7 -97.0 -55.9 -5.7 -8.3 19.7 105 107 A H S S- 0 0 0 -77,-0.1 7,-0.4 140,-0.1 2,-0.3 -0.422 75.7-158.8 -75.4 155.9 -7.7 -8.4 22.9 106 108 A T E -a 30 0A 12 -77,-1.3 -75,-3.2 5,-0.1 2,-0.5 -0.932 11.2-139.6-130.9 157.4 -8.3 -11.9 24.5 107 109 A V E > S-aB 31 110A 18 3,-1.8 3,-2.4 -2,-0.3 -75,-0.2 -0.981 87.7 -21.1-120.4 115.3 -11.0 -13.0 26.9 108 110 A D T 3 S- 0 0 69 -77,-3.4 -1,-0.2 -2,-0.5 -76,-0.1 0.894 129.3 -54.4 51.1 41.5 -9.7 -15.4 29.6 109 111 A K T 3 S+ 0 0 158 1,-0.2 2,-0.3 -78,-0.1 -1,-0.3 0.335 105.1 138.4 70.1 3.5 -6.9 -16.0 27.1 110 112 A K B < -B 107 0A 112 -3,-2.4 -3,-1.8 -9,-0.0 2,-0.4 -0.617 40.6-152.3 -80.2 130.1 -9.3 -16.9 24.3 111 113 A K - 0 0 90 -2,-0.3 2,-0.2 -11,-0.3 -5,-0.1 -0.807 5.8-149.8-100.4 141.7 -8.3 -15.5 20.9 112 114 A Y - 0 0 31 -7,-0.4 -9,-1.8 -2,-0.4 34,-0.2 -0.610 29.2-106.8-103.4 171.7 -10.9 -14.8 18.3 113 115 A A S S- 0 0 3 32,-1.0 -17,-1.3 -2,-0.2 2,-0.3 0.709 94.3 -7.1 -76.1 -17.4 -10.4 -15.0 14.5 114 116 A A E -IJ 95 145B 0 31,-1.2 31,-2.4 -19,-0.2 2,-0.4 -0.983 57.7-141.0-166.2 163.9 -10.4 -11.2 14.1 115 117 A E E -IJ 94 144B 0 -21,-2.6 -21,-2.3 -13,-0.3 2,-0.4 -0.991 12.5-148.8-142.5 125.3 -11.0 -7.9 15.9 116 118 A L E -IJ 93 143B 0 27,-2.8 27,-2.3 -2,-0.4 2,-0.5 -0.869 10.3-160.7 -88.4 133.0 -12.8 -4.8 14.5 117 119 A H E -IJ 92 142B 3 -25,-3.2 -25,-1.8 -2,-0.4 2,-0.7 -0.967 5.8-165.4-121.1 120.0 -11.7 -1.4 15.7 118 120 A L E -IJ 91 141B 0 23,-2.2 23,-2.1 -2,-0.5 2,-0.4 -0.926 19.0-151.3 -99.3 110.0 -14.0 1.7 15.3 119 121 A V E +IJ 90 140B 7 -29,-2.9 -30,-2.6 -2,-0.7 -29,-1.3 -0.774 18.7 175.7 -93.3 127.4 -11.8 4.7 15.9 120 122 A H E -IJ 88 139B 0 19,-1.9 19,-2.3 -2,-0.4 2,-0.4 -0.957 16.1-147.2-126.4 146.5 -13.4 7.9 17.3 121 123 A W E -IJ 87 138B 5 -34,-2.1 -34,-2.1 -2,-0.3 2,-0.4 -0.930 28.2-104.9-120.4 145.6 -11.8 11.3 18.4 122 124 A N E > -I 86 0B 3 15,-3.0 3,-2.3 -2,-0.4 -36,-0.2 -0.451 24.4-145.9 -64.1 111.7 -12.9 13.7 21.2 123 125 A T G > S+ 0 0 42 -38,-3.0 3,-1.6 -2,-0.4 -1,-0.1 0.687 91.6 74.8 -56.7 -21.4 -14.6 16.7 19.5 124 127 A K G 3 S+ 0 0 139 -39,-0.3 -1,-0.3 1,-0.3 -38,-0.1 0.764 92.1 57.9 -62.7 -22.4 -13.3 19.1 22.2 125 128 A Y G < S- 0 0 46 -3,-2.3 2,-1.2 12,-0.1 -1,-0.3 0.445 99.5-136.1 -86.8 -6.0 -9.9 18.7 20.6 126 129 A G S < S+ 0 0 52 -3,-1.6 2,-0.3 -4,-0.2 -1,-0.1 -0.211 73.0 23.3 80.8 -43.4 -10.9 20.0 17.2 127 130 A D S > S- 0 0 65 -2,-1.2 4,-2.5 -5,-0.2 3,-0.4 -0.966 78.7-108.3-152.1 167.6 -9.1 17.4 15.0 128 131 A F H > S+ 0 0 61 -2,-0.3 4,-2.0 1,-0.2 -6,-0.1 0.871 114.8 60.1 -61.0 -43.3 -7.7 13.8 15.2 129 132 A G H 4 S+ 0 0 37 1,-0.2 4,-0.3 2,-0.2 -1,-0.2 0.833 111.7 39.2 -57.8 -38.0 -4.1 15.1 15.2 130 133 A K H >4 S+ 0 0 103 -3,-0.4 3,-1.2 1,-0.2 -1,-0.2 0.865 109.7 60.3 -82.2 -39.8 -4.7 17.1 18.4 131 134 A A H >< S+ 0 0 0 -4,-2.5 3,-1.7 1,-0.2 6,-0.2 0.790 95.4 61.3 -58.1 -36.0 -6.8 14.4 20.0 132 135 A V T 3< S+ 0 0 23 -4,-2.0 -1,-0.2 1,-0.3 -2,-0.1 0.700 95.8 63.6 -66.7 -16.5 -4.0 11.7 20.0 133 136 A Q T < S+ 0 0 144 -3,-1.2 -1,-0.3 -4,-0.3 -2,-0.2 0.329 94.5 78.2 -83.3 3.2 -1.9 14.0 22.1 134 137 A Q S X S- 0 0 69 -3,-1.7 3,-1.8 69,-0.1 4,-0.3 -0.914 79.5-129.4-120.6 148.8 -4.4 13.7 25.0 135 138 A P T 3 S+ 0 0 78 0, 0.0 3,-0.1 0, 0.0 58,-0.1 0.685 115.2 32.5 -65.0 -25.6 -5.1 11.0 27.6 136 139 A D T 3 S+ 0 0 47 1,-0.1 -53,-0.1 -5,-0.1 -14,-0.1 -0.084 88.5 111.8-117.4 29.1 -8.8 11.1 26.8 137 140 A G S < S+ 0 0 0 -3,-1.8 -15,-3.0 -6,-0.2 2,-0.3 0.812 72.7 38.5 -75.1 -29.0 -8.4 12.0 23.1 138 141 A L E -Jk 121 204B 0 65,-3.0 67,-2.1 -4,-0.3 2,-0.4 -0.922 53.8-163.4-126.2 157.2 -9.7 8.8 21.5 139 142 A A E -Jk 120 205B 0 -19,-2.3 -19,-1.9 -2,-0.3 2,-0.5 -0.998 13.6-166.6-133.3 124.8 -12.3 6.2 22.1 140 143 A V E -Jk 119 206B 3 65,-2.1 67,-3.1 -2,-0.4 2,-0.6 -0.970 9.8-153.8-119.5 126.2 -12.0 2.8 20.3 141 144 A L E -Jk 118 207B 0 -23,-2.1 -23,-2.2 -2,-0.5 2,-0.5 -0.884 16.3-161.7 -91.4 115.5 -14.9 0.3 20.1 142 145 A G E -Jk 117 208B 0 65,-3.0 67,-2.3 -2,-0.6 2,-0.4 -0.905 8.9-176.3-102.9 135.9 -13.4 -3.2 19.7 143 146 A I E -J 116 0B 0 -27,-2.3 -27,-2.8 -2,-0.5 2,-0.2 -0.987 18.1-137.4-130.2 128.8 -15.6 -6.1 18.4 144 147 A F E -J 115 0B 0 65,-0.5 69,-2.6 -2,-0.4 2,-0.4 -0.581 12.3-151.2 -83.4 147.2 -14.5 -9.7 18.2 145 148 A L E -Jl 114 213B 0 -31,-2.4 -31,-1.2 67,-0.2 -32,-1.0 -0.965 11.8-172.7-113.0 133.9 -15.4 -11.8 15.1 146 149 A K E - l 0 214B 84 67,-2.5 69,-2.3 -2,-0.4 2,-0.5 -0.886 30.9-106.0-118.2 159.5 -15.8 -15.6 15.3 147 150 A V E S+ l 0 215B 48 -2,-0.3 69,-0.2 67,-0.2 2,-0.2 -0.693 75.6 92.4 -90.9 127.2 -16.3 -18.0 12.3 148 151 A G E S+ l 0 216B 40 67,-3.0 69,-0.5 -2,-0.5 2,-0.1 -0.559 78.6 11.6-167.2-124.6 -19.8 -19.3 11.9 149 152 A S S S- 0 0 89 -2,-0.2 -1,-0.3 67,-0.2 -3,-0.1 -0.401 84.2 -96.0 -69.7 150.1 -22.6 -17.8 9.8 150 153 A A - 0 0 59 65,-0.3 65,-0.1 -2,-0.1 -1,-0.1 -0.253 27.7-131.6 -65.4 148.1 -21.9 -15.0 7.3 151 154 A K >> - 0 0 46 1,-0.2 3,-1.4 62,-0.1 4,-0.8 -0.959 12.4-159.2-104.7 108.4 -22.5 -11.4 8.3 152 155 A P G >4 S+ 0 0 111 0, 0.0 3,-1.3 0, 0.0 4,-0.4 0.923 89.4 58.1 -55.7 -47.9 -24.6 -9.7 5.6 153 156 A G G 34 S+ 0 0 27 27,-0.4 4,-0.2 1,-0.3 27,-0.2 0.610 103.0 55.0 -59.6 -16.7 -23.5 -6.2 6.6 154 157 A L G X> S+ 0 0 2 -3,-1.4 4,-2.0 26,-0.2 3,-1.1 0.714 83.6 84.4 -92.4 -18.1 -19.9 -7.1 6.0 155 158 A Q H S+ 0 0 120 -4,-0.4 4,-0.8 1,-0.2 -1,-0.3 0.917 108.8 44.8 -58.3 -39.4 -19.9 -4.9 0.8 157 160 A V H X> S+ 0 0 0 -3,-1.1 3,-1.2 -4,-0.2 4,-1.0 0.954 110.6 53.6 -66.6 -50.9 -16.4 -4.6 2.4 158 161 A V H >< S+ 0 0 3 -4,-2.0 3,-0.9 1,-0.3 4,-0.4 0.903 105.7 54.8 -49.5 -48.9 -15.5 -8.1 1.4 159 162 A D H 3< S+ 0 0 98 -4,-2.7 3,-0.3 1,-0.2 -1,-0.3 0.671 104.7 50.4 -62.5 -28.4 -16.3 -7.5 -2.2 160 163 A V H XX S+ 0 0 26 -3,-1.2 3,-1.9 -4,-0.8 4,-0.5 0.565 83.4 92.5 -87.4 -11.7 -14.1 -4.3 -2.7 161 164 A L G X< S+ 0 0 7 -4,-1.0 3,-1.8 -3,-0.9 -1,-0.2 0.865 77.0 62.5 -51.3 -36.3 -10.9 -6.0 -1.3 162 165 A D G >4 S+ 0 0 137 -4,-0.4 3,-0.7 -3,-0.3 -1,-0.3 0.798 100.2 54.4 -59.9 -30.2 -9.8 -7.1 -4.8 163 166 A S G <4 S+ 0 0 60 -3,-1.9 -1,-0.3 1,-0.2 -2,-0.2 0.553 112.3 41.4 -83.4 -8.2 -9.6 -3.5 -5.8 164 167 A I G << S+ 0 0 0 -3,-1.8 -1,-0.2 -4,-0.5 63,-0.2 -0.202 72.9 139.2-129.3 44.0 -7.2 -2.5 -3.0 165 168 A K < + 0 0 68 -3,-0.7 62,-2.6 61,-0.1 2,-0.2 0.794 59.5 44.1 -58.1 -40.3 -5.0 -5.6 -3.0 166 169 A T S > S- 0 0 15 60,-0.2 3,-2.0 -3,-0.1 -107,-0.3 -0.703 98.4 -75.8-117.3 160.0 -1.6 -3.8 -2.4 167 170 A K B 3 S+o 230 0C 95 62,-2.5 64,-0.5 1,-0.3 -107,-0.2 -0.241 114.4 23.3 -51.2 130.2 -0.2 -1.1 -0.2 168 171 A G T 3 S+ 0 0 58 -109,-3.1 -1,-0.3 1,-0.4 2,-0.2 0.078 89.0 124.1 99.7 -18.8 -1.2 2.4 -1.3 169 172 A K < + 0 0 81 -3,-2.0 -110,-2.7 -5,-0.1 -1,-0.4 -0.476 33.9 176.9 -74.5 148.6 -4.4 1.5 -3.3 170 173 A S E -F 58 0B 57 -112,-0.2 2,-0.3 -2,-0.2 -112,-0.2 -0.926 10.9-163.2-144.5 162.1 -7.7 3.1 -2.4 171 174 A A E -F 57 0B 21 -114,-2.3 -114,-2.4 -2,-0.3 -116,-0.0 -0.994 34.4 -96.3-151.1 149.1 -11.2 3.0 -3.7 172 175 A D E -F 56 0B 142 -2,-0.3 -116,-0.3 -116,-0.2 -117,-0.1 -0.399 40.2-179.1 -62.8 138.2 -14.4 5.1 -3.4 173 176 A F + 0 0 16 -118,-1.9 3,-0.4 -106,-0.1 -117,-0.3 -0.505 13.1 164.8-147.3 69.7 -16.4 3.5 -0.6 174 177 A T + 0 0 84 -119,-0.2 -119,-0.2 1,-0.2 -121,-0.1 -0.485 52.8 21.1 -93.0 155.6 -19.7 5.5 -0.2 175 178 A N S S+ 0 0 131 -121,-0.7 2,-0.5 1,-0.2 -1,-0.2 0.782 73.4 151.7 62.0 33.4 -22.9 4.8 1.5 176 179 A F - 0 0 8 -3,-0.4 -122,-0.3 -20,-0.0 -1,-0.2 -0.808 34.8-149.0 -93.4 129.0 -21.6 2.0 3.8 177 180 A D > - 0 0 63 -2,-0.5 3,-1.5 1,-0.1 -127,-0.1 -0.897 7.4-162.2-102.9 111.5 -23.6 1.8 7.0 178 181 A P G > S+ 0 0 0 0, 0.0 3,-2.2 0, 0.0 4,-0.2 0.611 81.0 82.3 -70.6 -8.5 -21.5 0.6 10.0 179 182 A R G > S+ 0 0 123 1,-0.3 3,-1.3 -130,-0.3 -26,-0.1 0.775 78.3 70.3 -64.9 -21.7 -24.6 -0.3 12.0 180 183 A G G < S+ 0 0 31 -3,-1.5 -27,-0.4 1,-0.2 -1,-0.3 0.570 94.0 57.3 -73.9 -0.5 -24.5 -3.5 10.0 181 184 A L G < S+ 0 0 1 -3,-2.2 -1,-0.2 -28,-0.1 -2,-0.2 0.354 82.6 103.7-107.3 1.4 -21.4 -4.5 12.0 182 185 A L < - 0 0 32 -3,-1.3 4,-0.1 -4,-0.2 2,-0.1 -0.569 66.2-128.8 -89.0 145.4 -22.8 -4.3 15.6 183 186 A P - 0 0 11 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.312 33.0-104.3 -73.4 176.3 -23.7 -7.3 17.7 184 187 A E S S+ 0 0 186 -2,-0.1 2,-0.3 2,-0.0 29,-0.0 0.917 102.7 57.3 -67.3 -42.9 -27.2 -7.3 19.3 185 188 A S - 0 0 26 1,-0.1 26,-0.3 2,-0.1 24,-0.0 -0.688 60.0-161.8 -95.4 144.0 -25.9 -6.5 22.8 186 189 A L + 0 0 62 -2,-0.3 -141,-0.3 24,-0.1 -1,-0.1 0.100 43.2 135.3-111.0 20.4 -23.9 -3.5 23.8 187 190 A D + 0 0 58 -143,-0.1 23,-2.0 22,-0.1 24,-0.4 -0.425 35.1 169.8 -62.1 146.3 -22.5 -4.8 27.1 188 191 A Y E -M 209 0B 2 21,-0.2 68,-3.0 22,-0.1 2,-0.3 -0.951 38.8-126.3-156.5 171.6 -18.8 -4.1 27.4 189 192 A W E -MN 208 255B 13 19,-2.6 19,-2.6 -2,-0.3 2,-0.3 -0.867 29.1-165.5-115.8 155.1 -15.6 -3.9 29.3 190 193 A T E +MN 207 254B 9 64,-2.3 64,-2.6 -2,-0.3 17,-0.2 -0.997 17.0 154.5-145.3 146.3 -13.5 -0.6 29.5 191 194 A Y E -M 206 0B 5 15,-1.0 15,-3.0 -2,-0.3 2,-0.5 -0.947 46.1 -98.5-160.6 158.5 -10.0 0.3 30.5 192 195 A P E +M 205 0B 52 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.728 61.8 130.4 -86.2 131.2 -7.5 3.1 29.6 193 196 A G E -M 204 0B 0 11,-3.3 11,-1.8 -2,-0.5 2,-0.2 -0.528 42.2 -93.1-154.0-151.8 -4.9 2.1 27.0 194 197 A S - 0 0 0 9,-0.2 8,-0.2 8,-0.2 2,-0.1 -0.790 42.5 -72.5-132.8 178.7 -3.3 3.0 23.7 195 198 A L - 0 0 29 6,-1.5 -168,-0.4 -2,-0.2 9,-0.1 -0.485 41.4-137.1 -67.1 154.2 -3.2 2.6 19.9 196 199 A T S S+ 0 0 6 -2,-0.1 -1,-0.1 2,-0.1 -170,-0.0 0.370 83.6 52.7-104.2 4.6 -2.1 -0.9 19.0 197 200 A T S > S- 0 0 25 4,-0.1 3,-2.6 46,-0.0 4,-0.3 -0.923 103.8 -46.3-127.6 160.0 0.2 0.2 16.1 198 201 A P T 3 S+ 0 0 11 0, 0.0 -2,-0.1 0, 0.0 -180,-0.0 -0.293 123.0 47.5 -53.3 144.8 3.0 2.8 16.2 199 202 A P T 3 S- 0 0 64 0, 0.0 -179,-0.1 0, 0.0 -3,-0.0 -0.986 82.9-164.9 -76.7 9.6 3.0 5.5 17.4 200 203 A L < - 0 0 0 -3,-2.6 2,-0.1 1,-0.2 -173,-0.1 0.796 17.6-176.6 55.8 31.2 1.4 3.5 20.3 201 204 A L - 0 0 54 -4,-0.3 2,-2.3 1,-0.1 -6,-1.5 -0.315 30.4-130.6 -68.4 139.4 0.1 6.7 21.9 202 205 A E S S+ 0 0 49 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.325 73.9 111.7 -87.9 68.2 -1.6 6.2 25.2 203 206 A C + 0 0 1 -2,-2.3 -65,-3.0 -67,-0.1 2,-0.4 0.206 47.7 107.4-123.1 12.7 -4.6 8.3 24.3 204 207 A V E -kM 138 193B 0 -11,-1.8 -11,-3.3 -3,-0.3 2,-0.7 -0.824 48.9-161.1-110.4 141.1 -7.4 5.7 24.2 205 208 A T E -kM 139 192B 25 -67,-2.1 -65,-2.1 -2,-0.4 2,-0.4 -0.958 32.6-145.2-104.4 114.6 -10.3 4.7 26.3 206 209 A W E -kM 140 191B 4 -15,-3.0 -15,-1.0 -2,-0.7 2,-0.5 -0.720 18.5-172.5 -87.3 140.6 -11.0 1.2 25.0 207 210 A I E -kM 141 190B 0 -67,-3.1 -65,-3.0 -2,-0.4 2,-0.5 -0.980 9.6-175.6-128.3 104.6 -14.6 -0.1 24.9 208 211 A V E -kM 142 189B 0 -19,-2.6 -19,-2.6 -2,-0.5 2,-0.3 -0.978 20.9-132.2-108.6 119.3 -14.6 -3.9 24.0 209 212 A L E - M 0 188B 0 -67,-2.3 -65,-0.5 -2,-0.5 -21,-0.2 -0.572 2.8-141.7 -75.5 139.0 -18.0 -5.5 23.5 210 213 A K S S+ 0 0 64 -23,-2.0 -22,-0.1 -2,-0.3 -1,-0.1 0.834 83.7 70.0 -63.5 -41.4 -18.7 -8.7 25.2 211 214 A E S S- 0 0 56 -24,-0.4 -67,-0.1 -26,-0.3 -2,-0.1 -0.772 73.6-148.7 -91.0 121.1 -20.7 -10.3 22.3 212 215 A P - 0 0 33 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.292 12.0-128.6 -78.7 166.7 -18.8 -11.2 19.2 213 216 A I E -l 145 0B 6 -69,-2.6 -67,-2.5 -30,-0.1 2,-0.4 -0.844 22.8-124.3-108.0 154.4 -20.2 -11.1 15.7 214 217 A S E -l 146 0B 31 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.806 26.3-179.0 -99.9 142.6 -20.0 -14.1 13.4 215 218 A V E -l 147 0B 0 -69,-2.3 -67,-3.0 -2,-0.4 -65,-0.3 -0.906 31.0-105.0-126.3 159.6 -18.5 -14.1 9.9 216 219 A S E > -l 148 0B 13 -2,-0.3 4,-2.5 -69,-0.2 3,-0.5 -0.439 26.4-115.4 -87.0 159.4 -18.3 -16.9 7.5 217 220 A S H > S+ 0 0 44 -69,-0.5 4,-2.0 1,-0.3 -1,-0.1 0.880 118.2 53.0 -54.6 -38.3 -15.1 -18.7 6.8 218 221 A E H > S+ 0 0 126 2,-0.2 4,-1.4 1,-0.2 -1,-0.3 0.781 104.9 53.4 -72.5 -32.2 -15.2 -17.4 3.2 219 222 A Q H > S+ 0 0 3 -3,-0.5 4,-0.9 2,-0.2 3,-0.4 0.945 112.7 44.6 -66.7 -48.9 -15.6 -13.8 4.3 220 223 A V H X S+ 0 0 0 -4,-2.5 4,-1.2 1,-0.2 3,-0.5 0.840 106.4 62.0 -64.2 -31.7 -12.5 -14.2 6.5 221 224 A L H < S+ 0 0 78 -4,-2.0 -1,-0.2 1,-0.2 3,-0.2 0.853 98.5 55.4 -62.2 -40.9 -10.7 -15.9 3.6 222 225 A K H >< S+ 0 0 91 -4,-1.4 3,-0.9 -3,-0.4 -1,-0.2 0.784 102.4 57.0 -63.6 -27.6 -11.0 -12.8 1.4 223 226 A F H >< S+ 0 0 0 -4,-0.9 3,-1.9 -3,-0.5 -1,-0.2 0.915 100.7 57.5 -62.3 -47.5 -9.2 -10.7 4.1 224 227 A R T 3< S+ 0 0 29 -4,-1.2 -1,-0.2 1,-0.3 -2,-0.2 0.426 93.7 70.9 -63.2 -6.5 -6.2 -13.1 4.0 225 228 A K T < S+ 0 0 123 -3,-0.9 -1,-0.3 -4,-0.2 -2,-0.2 0.555 76.9 101.0 -90.8 -11.6 -5.9 -12.4 0.3 226 229 A L < - 0 0 3 -3,-1.9 12,-3.3 12,-0.3 2,-0.4 -0.185 67.0-127.0 -72.8 163.9 -4.6 -8.8 0.8 227 230 A N B -P 237 0D 7 -62,-2.6 -166,-0.2 10,-0.3 10,-0.2 -0.918 16.1-158.3-119.2 147.8 -1.0 -7.8 0.6 228 231 A F S S+ 0 0 33 8,-2.4 -1,-0.1 -2,-0.4 9,-0.1 0.806 80.1 81.3 -78.3 -38.3 1.4 -6.0 2.9 229 232 A N S S- 0 0 3 7,-0.7 -62,-2.5 5,-0.1 -2,-0.1 -0.163 84.0-114.7 -71.1 159.6 3.5 -5.2 -0.2 230 233 A G B > -o 167 0C 6 -64,-0.3 3,-1.4 1,-0.2 -62,-0.1 -0.465 53.3 -70.6 -86.0 164.2 3.0 -2.5 -2.8 231 234 A E T 3 S+ 0 0 139 -64,-0.5 -1,-0.2 1,-0.3 4,-0.0 -0.263 120.1 21.2 -59.3 139.1 2.3 -3.4 -6.3 232 235 A G T 3 S+ 0 0 86 1,-0.3 -1,-0.3 -3,-0.1 -2,-0.1 0.652 100.7 109.3 75.8 15.9 5.1 -5.0 -8.3 233 236 A E S < S- 0 0 92 -3,-1.4 -1,-0.3 1,-0.1 3,-0.1 -0.780 85.6 -77.1-112.2 162.2 6.9 -6.1 -5.1 234 237 A P - 0 0 113 0, 0.0 2,-0.4 0, 0.0 -5,-0.1 -0.323 60.4 -97.9 -63.1 140.0 7.1 -9.7 -4.0 235 238 A E + 0 0 125 -7,-0.1 2,-0.5 -6,-0.1 -8,-0.0 -0.521 42.6 173.5 -70.2 121.8 3.9 -10.9 -2.5 236 239 A E - 0 0 105 -2,-0.4 -8,-2.4 -3,-0.1 -7,-0.7 -0.995 32.1-129.1-125.5 110.5 3.6 -11.0 1.3 237 240 A L B -P 227 0D 83 -2,-0.5 2,-1.4 -10,-0.2 -10,-0.3 -0.389 18.6-119.1 -66.2 139.7 0.1 -11.9 2.4 238 241 A M + 0 0 0 -12,-3.3 -12,-0.3 -15,-0.2 2,-0.3 -0.641 64.1 129.7 -80.8 95.8 -1.5 -9.5 4.9 239 242 A V + 0 0 34 -2,-1.4 -143,-0.2 1,-0.1 -142,-0.1 -0.947 51.8 26.9-145.5 157.2 -2.1 -11.9 7.8 240 243 A D + 0 0 42 -145,-0.7 2,-1.0 -2,-0.3 -144,-0.2 0.856 62.8 159.8 56.5 42.4 -1.4 -11.9 11.6 241 244 A N + 0 0 0 -146,-1.2 2,-0.3 -3,-0.1 -1,-0.2 -0.347 36.7 114.9 -91.3 57.0 -1.5 -8.1 11.8 242 245 A W - 0 0 46 -2,-1.0 -138,-0.1 -148,-0.1 -139,-0.1 -0.933 61.4-136.3-132.0 142.3 -2.1 -8.3 15.5 243 246 A R - 0 0 5 -2,-0.3 3,-0.1 1,-0.1 -2,-0.1 -0.836 31.4-116.3 -97.7 136.6 -0.1 -7.2 18.5 244 247 A P - 0 0 61 0, 0.0 -140,-0.1 0, 0.0 -139,-0.1 -0.266 44.7 -74.4 -67.3 166.1 0.0 -9.6 21.4 245 248 A A - 0 0 48 -141,-0.1 -216,-0.3 -216,-0.1 -218,-0.1 -0.184 49.3-147.8 -65.0 136.3 -1.4 -8.8 24.9 246 249 A Q - 0 0 46 -218,-2.6 -216,-0.4 -220,-0.1 -1,-0.1 -0.775 31.3 -76.8-106.6 156.9 0.6 -6.4 27.1 247 250 A P - 0 0 71 0, 0.0 -221,-0.3 0, 0.0 -1,-0.1 -0.339 30.5-143.9 -58.5 138.3 1.0 -6.2 30.8 248 251 A L + 0 0 56 1,-0.2 3,-0.1 -223,-0.1 -2,-0.0 0.797 37.0 167.0 -68.6 -39.8 -1.9 -4.7 32.7 249 252 A K - 0 0 98 1,-0.2 2,-1.4 -224,-0.1 -1,-0.2 -0.232 66.7 -2.0 56.5-134.2 0.3 -2.9 35.2 250 253 A N S S+ 0 0 158 -226,-0.3 2,-0.4 2,-0.0 -1,-0.2 -0.155 107.7 113.8 -80.6 45.8 -1.6 -0.3 37.3 251 254 A R - 0 0 30 -2,-1.4 2,-0.4 -3,-0.1 -3,-0.1 -0.927 50.4-152.6-127.4 150.9 -5.0 -0.7 35.6 252 255 A Q - 0 0 110 -2,-0.4 2,-0.5 -216,-0.0 -216,-0.1 -0.863 14.1-143.9-111.9 134.9 -8.5 -1.9 36.4 253 256 A I - 0 0 10 -2,-0.4 -216,-2.1 -218,-0.2 2,-0.3 -0.906 20.7-156.7 -96.3 129.4 -10.8 -3.4 33.7 254 257 A K E -cN 37 190B 55 -64,-2.6 -64,-2.3 -2,-0.5 2,-0.4 -0.808 1.4-147.5-105.7 149.2 -14.4 -2.3 34.5 255 258 A A E -cN 38 189B 4 -218,-3.1 -216,-2.6 -2,-0.3 -66,-0.2 -0.943 12.0-151.2-115.7 145.1 -17.5 -4.2 33.2 256 259 A S S S+ 0 0 29 -68,-3.0 2,-0.3 -2,-0.4 -67,-0.1 0.408 83.7 40.8 -88.0 -0.1 -20.8 -2.6 32.3 257 260 A F 0 0 41 -69,-0.3 -218,-0.1 1,-0.1 -2,-0.0 -0.927 360.0 360.0-141.7 166.5 -22.6 -5.8 33.3 258 261 A K 0 0 224 -2,-0.3 -1,-0.1 -220,-0.1 -220,-0.0 0.722 360.0 360.0-120.2 360.0 -22.6 -8.6 35.8