==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=12-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 05-MAY-04 1T69 . COMPND 2 MOLECULE: HISTONE DEACETYLASE 8; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR J.R.SOMOZA,R.J.SKENE,B.A.KATZ,C.MOL,J.D.HO,A.J.JENNINGS, . 358 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14051.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 261 72.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 39 10.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 32 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 49 13.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 112 31.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 1 0 1 1 1 1 1 0 0 1 1 0 0 1 0 1 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 1 1 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 14 A L 0 0 139 0, 0.0 112,-0.1 0, 0.0 113,-0.1 0.000 360.0 360.0 360.0 2.9 34.7 12.7 19.6 2 15 A V - 0 0 73 110,-0.2 39,-0.1 1,-0.1 40,-0.0 -0.779 360.0 -89.9-102.8 146.9 35.5 13.9 16.1 3 16 A P - 0 0 19 0, 0.0 39,-2.6 0, 0.0 2,-0.5 -0.207 33.1-124.6 -60.2 143.3 35.2 11.5 13.0 4 17 A V E -ab 42 116A 0 111,-2.3 113,-3.1 37,-0.2 2,-0.5 -0.767 22.2-162.2 -88.1 126.3 38.2 9.4 11.7 5 18 A Y E -ab 43 117A 9 37,-2.9 39,-2.9 -2,-0.5 2,-0.9 -0.949 13.9-138.4-115.0 120.2 39.0 10.0 8.0 6 19 A I E +a 44 0A 8 111,-2.2 2,-0.3 -2,-0.5 114,-0.2 -0.675 45.4 141.4 -85.0 105.9 41.1 7.3 6.4 7 20 A Y + 0 0 51 37,-1.4 3,-0.1 -2,-0.9 -2,-0.1 -0.997 16.8 146.1-147.1 141.4 43.7 9.1 4.1 8 21 A S > - 0 0 5 -2,-0.3 4,-2.8 37,-0.1 5,-0.3 -0.896 47.9-122.5-156.2 152.3 47.2 9.1 2.9 9 22 A P H > S+ 0 0 87 0, 0.0 4,-2.8 0, 0.0 5,-0.2 0.923 116.6 53.6 -55.7 -41.7 48.7 10.1 -0.4 10 23 A E H > S+ 0 0 62 2,-0.2 4,-1.5 1,-0.2 5,-0.1 0.836 113.4 42.5 -61.0 -38.6 50.2 6.5 -0.7 11 24 A Y H > S+ 0 0 6 2,-0.2 4,-2.6 3,-0.1 3,-0.3 0.982 114.3 48.7 -69.7 -61.6 46.7 5.1 -0.1 12 25 A V H X S+ 0 0 13 -4,-2.8 4,-1.2 1,-0.2 14,-0.4 0.860 113.1 48.7 -47.1 -43.9 44.8 7.5 -2.4 13 26 A S H X S+ 0 0 73 -4,-2.8 4,-0.7 -5,-0.3 3,-0.3 0.890 108.9 52.0 -71.3 -38.2 47.3 6.9 -5.2 14 27 A M H >< S+ 0 0 55 -4,-1.5 3,-1.0 -3,-0.3 -1,-0.2 0.928 111.2 50.0 -54.8 -44.8 47.1 3.1 -4.8 15 28 A C H >< S+ 0 0 3 -4,-2.6 3,-0.5 1,-0.3 9,-0.2 0.671 104.2 57.0 -71.3 -21.2 43.3 3.6 -5.0 16 29 A D H 3< S+ 0 0 25 -4,-1.2 7,-0.7 -3,-0.3 -1,-0.3 0.634 97.3 65.7 -78.2 -17.2 43.6 5.7 -8.2 17 30 A S T << + 0 0 58 -3,-1.0 2,-0.5 -4,-0.7 -1,-0.2 0.501 68.3 111.3 -87.8 -4.4 45.4 2.8 -9.8 18 31 A L X - 0 0 10 -3,-0.5 3,-1.6 3,-0.3 -3,-0.0 -0.631 69.9-138.3 -69.7 118.8 42.4 0.5 -9.8 19 32 A A T 3 S+ 0 0 60 -2,-0.5 -1,-0.1 1,-0.3 65,-0.0 0.773 93.3 59.8 -50.2 -40.8 41.6 0.3 -13.5 20 33 A K T 3 S+ 0 0 63 1,-0.3 -1,-0.3 63,-0.1 -2,-0.0 0.609 120.7 24.1 -76.2 -9.2 37.8 0.5 -13.4 21 34 A I S X S- 0 0 18 -3,-1.6 3,-1.3 -6,-0.1 4,-0.3 -0.467 77.7-171.8-150.4 71.2 37.9 3.9 -11.7 22 35 A P T 3 S+ 0 0 72 0, 0.0 -5,-0.2 0, 0.0 -6,-0.1 -0.482 75.0 4.5 -68.9 133.9 41.2 5.8 -12.4 23 36 A K T 3> S+ 0 0 127 -7,-0.7 4,-1.8 -2,-0.2 -7,-0.1 0.513 89.7 122.6 72.6 13.4 41.6 9.0 -10.4 24 37 A R H <> S+ 0 0 10 -3,-1.3 4,-2.6 -9,-0.2 -8,-0.1 0.893 75.8 43.5 -70.9 -38.9 38.4 8.6 -8.4 25 38 A A H > S+ 0 0 9 -4,-0.3 4,-2.8 -13,-0.2 5,-0.4 0.939 112.2 53.2 -73.7 -47.0 40.0 8.7 -4.9 26 39 A S H > S+ 0 0 25 -14,-0.4 4,-2.6 1,-0.2 -2,-0.2 0.955 114.2 44.6 -38.6 -59.2 42.3 11.6 -5.8 27 40 A M H X S+ 0 0 12 -4,-1.8 4,-2.4 2,-0.2 -2,-0.2 0.883 114.5 47.8 -59.2 -46.1 39.1 13.3 -6.9 28 41 A V H X S+ 0 0 5 -4,-2.6 4,-1.9 2,-0.2 3,-0.4 0.993 116.0 41.3 -61.8 -63.7 37.1 12.3 -3.8 29 42 A H H X S+ 0 0 10 -4,-2.8 4,-3.3 1,-0.2 -1,-0.2 0.873 114.3 57.4 -50.9 -39.0 39.7 13.3 -1.3 30 43 A S H X S+ 0 0 5 -4,-2.6 4,-3.0 -5,-0.4 -1,-0.2 0.900 104.4 46.7 -63.6 -48.5 40.4 16.4 -3.4 31 44 A L H X S+ 0 0 0 -4,-2.4 4,-1.3 -3,-0.4 -1,-0.2 0.834 116.4 48.5 -63.7 -30.7 36.9 17.9 -3.4 32 45 A I H <>S+ 0 0 0 -4,-1.9 5,-1.3 -5,-0.2 6,-0.5 0.925 110.8 48.0 -72.5 -46.3 36.9 17.2 0.4 33 46 A E H ><5S+ 0 0 88 -4,-3.3 3,-1.8 1,-0.2 -2,-0.2 0.925 110.3 55.7 -54.6 -44.8 40.3 18.8 0.9 34 47 A A H 3<5S+ 0 0 31 -4,-3.0 -1,-0.2 1,-0.3 -2,-0.2 0.804 107.2 45.9 -60.7 -36.9 38.9 21.7 -1.2 35 48 A Y T 3<5S- 0 0 26 -4,-1.3 -1,-0.3 -3,-0.2 -2,-0.2 0.309 110.4-128.5 -86.5 5.5 36.0 22.2 1.2 36 49 A A T X 5 + 0 0 36 -3,-1.8 3,-2.0 1,-0.1 4,-0.4 0.502 67.4 135.5 60.2 9.9 38.5 21.9 4.0 37 50 A L G > < + 0 0 2 -5,-1.3 3,-0.8 1,-0.3 -4,-0.2 0.697 59.0 69.4 -61.2 -21.9 36.4 19.2 5.7 38 51 A H G > S+ 0 0 27 -6,-0.5 3,-0.9 1,-0.2 -1,-0.3 0.740 90.5 61.9 -69.2 -18.5 39.4 17.1 6.4 39 52 A K G < S+ 0 0 170 -3,-2.0 -1,-0.2 1,-0.2 -2,-0.2 0.709 99.9 54.2 -81.1 -17.3 40.5 19.7 8.9 40 53 A Q G < S+ 0 0 72 -3,-0.8 2,-0.3 -4,-0.4 -1,-0.2 0.266 107.0 64.6 -92.2 9.0 37.4 19.0 10.9 41 54 A M S < S- 0 0 11 -3,-0.9 2,-0.7 -39,-0.1 -37,-0.2 -0.929 89.5-110.0-128.4 154.8 38.2 15.2 11.0 42 55 A R E -a 4 0A 123 -39,-2.6 -37,-2.9 -2,-0.3 2,-0.5 -0.759 36.5-140.4 -81.3 113.7 41.0 13.2 12.6 43 56 A I E -a 5 0A 76 -2,-0.7 2,-0.5 -39,-0.2 -37,-0.2 -0.665 19.5-165.2 -80.0 123.5 43.0 12.0 9.6 44 57 A V E -a 6 0A 19 -39,-2.9 -37,-1.4 -2,-0.5 60,-0.1 -0.949 16.3-133.9-114.7 126.9 44.2 8.4 10.1 45 58 A K - 0 0 153 -2,-0.5 2,-0.2 -39,-0.2 -37,-0.1 -0.607 30.1-122.7 -74.0 130.6 46.9 6.7 8.1 46 59 A P - 0 0 20 0, 0.0 54,-0.2 0, 0.0 53,-0.1 -0.560 19.9-129.7 -82.1 138.7 45.8 3.2 7.0 47 60 A K - 0 0 55 52,-0.6 2,-0.6 -2,-0.2 56,-0.2 -0.332 26.9-101.1 -76.6 162.1 47.8 0.1 7.9 48 61 A V - 0 0 116 51,-0.1 2,-0.5 -2,-0.1 48,-0.2 -0.784 39.9-119.1 -83.2 122.3 48.9 -2.6 5.4 49 62 A A - 0 0 6 46,-2.1 50,-0.1 -2,-0.6 5,-0.1 -0.515 32.4-128.2 -67.3 114.1 46.6 -5.6 5.8 50 63 A S > - 0 0 53 -2,-0.5 4,-2.2 1,-0.1 5,-0.4 -0.223 21.1-106.6 -62.6 151.3 48.8 -8.5 6.9 51 64 A M H > S+ 0 0 58 1,-0.2 4,-1.1 2,-0.2 3,-0.2 0.895 125.7 42.1 -40.2 -52.3 48.7 -11.8 5.0 52 65 A E H > S+ 0 0 67 2,-0.2 4,-0.8 1,-0.2 3,-0.4 0.920 106.7 61.0 -61.3 -50.3 46.8 -13.2 8.0 53 66 A E H 4 S+ 0 0 62 1,-0.3 3,-0.4 2,-0.2 -1,-0.2 0.832 111.1 40.7 -48.4 -40.2 44.6 -10.1 8.6 54 67 A M H >X S+ 0 0 3 -4,-2.2 4,-2.1 1,-0.2 3,-1.5 0.774 104.1 69.4 -76.5 -30.1 43.1 -10.7 5.1 55 68 A A H 3< S+ 0 0 36 -4,-1.1 -2,-0.2 -3,-0.4 -1,-0.2 0.591 72.6 88.8 -70.2 -12.1 43.0 -14.4 5.7 56 69 A T T 3< S+ 0 0 66 -4,-0.8 -1,-0.3 -3,-0.4 -2,-0.1 0.899 116.7 0.2 -44.0 -43.0 40.3 -13.9 8.2 57 70 A F T <4 S+ 0 0 29 -3,-1.5 2,-0.5 -4,-0.2 -2,-0.2 0.724 119.1 76.5-122.7 -40.9 37.9 -14.2 5.3 58 71 A H S < S- 0 0 0 -4,-2.1 2,-0.3 1,-0.1 71,-0.2 -0.704 85.8-114.3 -86.9 123.3 39.8 -14.9 2.0 59 72 A T >> - 0 0 54 69,-1.0 3,-1.5 -2,-0.5 4,-0.6 -0.378 28.8-121.6 -61.2 117.8 41.2 -18.4 1.6 60 73 A D H 3> S+ 0 0 69 1,-0.3 4,-0.7 -2,-0.3 5,-0.2 0.567 106.1 65.9 -41.1 -32.1 45.0 -18.2 1.7 61 74 A A H >> S+ 0 0 45 2,-0.2 4,-2.9 1,-0.2 3,-1.7 0.978 104.0 48.0 -52.9 -58.8 45.6 -19.8 -1.7 62 75 A Y H <> S+ 0 0 0 -3,-1.5 4,-3.0 1,-0.3 5,-0.3 0.932 109.9 50.7 -37.7 -64.8 43.8 -16.7 -3.3 63 76 A L H 3< S+ 0 0 0 -4,-0.6 -1,-0.3 1,-0.3 -2,-0.2 0.524 114.6 45.5 -64.0 -6.3 45.9 -14.3 -1.2 64 77 A Q H XX S+ 0 0 114 -3,-1.7 4,-1.5 -4,-0.7 3,-0.6 0.745 113.1 48.0-100.8 -39.4 49.0 -16.0 -2.3 65 78 A H H 3X S+ 0 0 13 -4,-2.9 4,-2.9 -3,-0.3 3,-0.4 0.959 107.5 55.8 -62.0 -54.2 48.1 -16.3 -6.0 66 79 A L H 3X S+ 0 0 1 -4,-3.0 4,-0.7 1,-0.2 25,-0.5 0.559 106.1 54.9 -56.0 -13.0 47.1 -12.6 -6.1 67 80 A Q H <4 S+ 0 0 90 -3,-0.6 -1,-0.2 -5,-0.3 -2,-0.2 0.864 110.0 41.0 -89.0 -45.4 50.6 -11.8 -4.8 68 81 A K H >< S+ 0 0 156 -4,-1.5 3,-2.7 -3,-0.4 -2,-0.2 0.963 116.0 52.0 -62.0 -52.1 52.6 -13.6 -7.5 69 82 A V H 3< S+ 0 0 40 -4,-2.9 -1,-0.2 1,-0.3 -3,-0.2 0.908 104.8 56.1 -50.0 -47.0 50.2 -12.4 -10.1 70 83 A S T 3< 0 0 15 -4,-0.7 -1,-0.3 -5,-0.3 -2,-0.2 0.354 360.0 360.0 -71.9 8.7 50.7 -8.8 -8.8 71 84 A Q < 0 0 117 -3,-2.7 -2,-0.1 17,-0.1 -3,-0.1 0.392 360.0 360.0-114.5 360.0 54.5 -9.3 -9.5 72 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 73 91 A P 0 0 148 0, 0.0 4,-0.1 0, 0.0 3,-0.1 0.000 360.0 360.0 360.0 -64.2 46.4 -19.5 -16.4 74 92 A D > + 0 0 49 1,-0.1 4,-1.0 2,-0.1 -5,-0.1 0.217 360.0 82.2-100.3 8.0 45.8 -19.8 -12.6 75 93 A S T 4>S+ 0 0 25 2,-0.2 5,-1.0 1,-0.2 -1,-0.1 0.748 81.4 55.9 -83.5 -30.0 43.9 -16.5 -12.9 76 94 A I T >45S+ 0 0 122 1,-0.2 3,-0.7 3,-0.1 -1,-0.2 0.777 103.6 56.1 -80.5 -28.3 40.6 -17.8 -14.1 77 95 A E T 345S+ 0 0 68 1,-0.2 2,-2.1 -4,-0.1 -2,-0.2 0.988 100.7 57.3 -58.2 -62.9 40.3 -20.1 -11.1 78 96 A Y T 3<5S- 0 0 64 -4,-1.0 53,-1.2 1,-0.2 -1,-0.2 -0.073 122.4-100.3 -69.6 38.9 40.7 -17.3 -8.5 79 97 A G T < 5S+ 0 0 20 -2,-2.1 -1,-0.2 -3,-0.7 -3,-0.1 0.304 77.1 142.0 67.3 -11.6 37.6 -15.4 -10.0 80 98 A L < + 0 0 11 -5,-1.0 2,-0.2 1,-0.1 -1,-0.2 -0.265 18.2 123.3 -58.9 147.7 39.8 -13.0 -12.0 81 99 A G S S- 0 0 48 3,-1.4 -1,-0.1 -3,-0.1 51,-0.0 -0.741 76.6 -41.8-168.0-143.8 38.4 -12.0 -15.4 82 100 A Y S S+ 0 0 200 -2,-0.2 -1,-0.1 1,-0.2 -2,-0.1 0.937 135.1 50.2 -71.0 -49.2 37.4 -9.0 -17.4 83 101 A D S S+ 0 0 64 1,-0.3 -1,-0.2 48,-0.1 -63,-0.1 0.781 121.5 37.7 -56.2 -30.8 35.6 -7.4 -14.4 84 102 A C S S- 0 0 2 -5,-0.1 -3,-1.4 47,-0.1 -1,-0.3 -0.766 80.8-165.2-132.1 86.6 38.8 -8.0 -12.4 85 103 A P - 0 0 38 0, 0.0 -4,-0.1 0, 0.0 -3,-0.1 0.034 25.8-123.4 -55.8 175.0 42.1 -7.5 -14.3 86 104 A A + 0 0 41 -6,-0.1 4,-0.1 -17,-0.1 -6,-0.0 -0.085 40.2 174.5-116.1 31.7 45.4 -8.9 -13.0 87 105 A T > - 0 0 59 1,-0.1 3,-1.7 2,-0.1 2,-1.0 -0.141 43.8 -97.3 -45.6 112.2 47.3 -5.6 -13.0 88 106 A E T 3 S+ 0 0 57 1,-0.3 -1,-0.1 2,-0.1 -18,-0.1 -0.704 111.1 28.0 -66.9 106.0 50.7 -6.1 -11.5 89 107 A G T >> + 0 0 23 -2,-1.0 4,-0.8 -23,-0.1 3,-0.6 -0.019 65.3 125.3-139.6 107.0 50.2 -5.2 -8.7 90 108 A I H <> + 0 0 2 -3,-1.7 4,-3.3 1,-0.2 5,-0.5 0.696 69.8 80.8 -69.5 -24.2 46.7 -5.4 -7.3 91 109 A F H 3> S+ 0 0 25 -25,-0.5 4,-1.9 1,-0.3 -1,-0.2 0.915 100.4 39.1 -55.1 -43.1 47.9 -7.4 -4.3 92 110 A D H <> S+ 0 0 88 -3,-0.6 4,-0.7 2,-0.2 -1,-0.3 0.846 114.0 56.6 -72.7 -32.5 49.0 -4.1 -2.7 93 111 A Y H >X S+ 0 0 2 -4,-0.8 4,-1.4 2,-0.2 3,-1.2 0.979 113.5 37.9 -61.3 -58.9 45.8 -2.4 -4.0 94 112 A A H 3X S+ 0 0 0 -4,-3.3 4,-2.3 1,-0.2 5,-0.3 0.891 113.1 58.7 -55.8 -42.7 43.5 -4.8 -2.3 95 113 A A H 3X S+ 0 0 3 -4,-1.9 -46,-2.1 -5,-0.5 4,-0.7 0.623 105.6 50.8 -67.3 -11.8 45.8 -5.0 0.7 96 114 A A H S+ 0 0 5 -4,-1.9 5,-2.6 2,-0.2 4,-0.8 0.947 109.2 51.7 -55.7 -51.7 39.5 3.2 15.6 108 126 A L H <5S+ 0 0 3 -4,-1.7 -2,-0.2 1,-0.2 -1,-0.2 0.836 114.2 42.8 -55.4 -38.1 35.8 2.4 16.2 109 127 A I H <5S+ 0 0 24 -4,-1.7 -1,-0.2 1,-0.2 -2,-0.2 0.664 110.2 54.5 -88.7 -16.7 36.7 -0.4 18.5 110 128 A D H <5S- 0 0 97 -4,-1.7 -1,-0.2 -3,-0.4 -2,-0.2 0.542 116.9-115.0 -81.8 -10.0 39.5 1.5 20.3 111 129 A G T <5S+ 0 0 55 -4,-0.8 -3,-0.2 -5,-0.2 -4,-0.1 0.650 72.8 140.3 80.6 17.5 36.9 4.1 21.0 112 130 A M S + c 0 283A 1 164,-3.3 3,-3.3 -2,-0.4 166,-1.0 -0.439 3.2 171.7-141.6 66.6 36.8 5.0 4.1 119 137 A W T 3 S+ 0 0 8 1,-0.3 166,-0.5 164,-0.2 165,-0.4 0.832 78.1 62.9 -45.2 -42.5 35.4 6.3 0.8 120 138 A S T 3 S+ 0 0 20 -114,-0.2 -1,-0.3 164,-0.1 2,-0.1 0.550 101.7 61.5 -58.5 -13.9 37.9 4.2 -1.1 121 139 A G < + 0 0 1 -3,-3.3 163,-0.6 161,-0.2 3,-0.1 -0.298 45.3 105.8-102.9-170.4 36.5 0.9 0.4 122 140 A G + 0 0 1 161,-0.2 2,-1.7 1,-0.1 164,-0.2 0.729 31.5 163.6 107.0 32.0 33.1 -0.8 0.2 123 141 A W + 0 0 19 14,-0.3 3,-0.5 1,-0.1 2,-0.2 -0.520 6.2 172.0 -85.5 76.1 33.8 -3.7 -2.2 124 142 A H + 0 0 4 -2,-1.7 42,-2.3 1,-0.2 43,-0.9 0.147 61.0 60.5 -78.9 19.6 30.7 -5.8 -1.3 125 143 A H + 0 0 7 -2,-0.2 -1,-0.2 7,-0.2 8,-0.2 0.785 65.1 106.9-117.7 -44.1 31.1 -8.4 -4.1 126 144 A A - 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