==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=25-SEP-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 03-AUG-11 3T9L . COMPND 2 MOLECULE: UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.HARPER,T.M.D.BESONG,J.EMSLEY,D.J.SCOTT,I.DREVENY . 222 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13405.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 135 60.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 10 4.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 37 16.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 15 6.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 24 10.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 41 18.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 0 1 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 6 A A 0 0 110 0, 0.0 3,-0.1 0, 0.0 97,-0.1 0.000 360.0 360.0 360.0 153.1 16.9 -37.5 -3.0 2 7 A A - 0 0 30 92,-0.1 5,-0.0 1,-0.1 0, 0.0 -0.259 360.0 -91.5 -55.8 154.1 18.7 -37.7 0.4 3 8 A D > - 0 0 84 1,-0.1 4,-2.5 4,-0.0 5,-0.2 -0.171 39.1-101.9 -65.4 167.1 20.8 -40.9 0.9 4 9 A L H > S+ 0 0 39 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.852 121.4 49.6 -64.3 -36.9 19.1 -43.9 2.5 5 10 A D H > S+ 0 0 84 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.894 111.4 49.2 -70.4 -39.0 20.8 -43.4 5.9 6 11 A T H > S+ 0 0 51 2,-0.2 4,-3.2 1,-0.2 5,-0.3 0.914 111.8 49.6 -62.8 -43.1 19.8 -39.7 5.9 7 12 A Q H X S+ 0 0 6 -4,-2.5 4,-2.4 2,-0.2 5,-0.3 0.943 111.8 47.4 -61.6 -46.9 16.2 -40.7 5.1 8 13 A R H X S+ 0 0 60 -4,-2.4 4,-2.1 1,-0.2 -2,-0.2 0.931 117.6 43.0 -59.8 -46.3 16.0 -43.3 7.8 9 14 A S H X S+ 0 0 70 -4,-2.4 4,-2.2 2,-0.2 -2,-0.2 0.931 114.5 48.4 -63.7 -51.9 17.5 -40.8 10.4 10 15 A D H X S+ 0 0 40 -4,-3.2 4,-2.3 1,-0.2 -2,-0.2 0.916 116.0 42.6 -58.8 -48.2 15.5 -37.8 9.3 11 16 A I H X S+ 0 0 0 -4,-2.4 4,-2.7 -5,-0.3 -1,-0.2 0.887 109.6 56.8 -72.2 -37.4 12.1 -39.6 9.3 12 17 A A H X S+ 0 0 33 -4,-2.1 4,-0.6 -5,-0.3 -1,-0.2 0.935 111.8 44.7 -55.9 -45.1 12.9 -41.5 12.6 13 18 A T H >< S+ 0 0 85 -4,-2.2 3,-1.2 1,-0.2 -2,-0.2 0.943 113.3 49.0 -62.1 -49.1 13.4 -38.1 14.2 14 19 A L H >< S+ 0 0 15 -4,-2.3 3,-1.5 1,-0.3 -2,-0.2 0.819 100.7 63.4 -67.7 -30.9 10.3 -36.5 12.7 15 20 A L H 3< S+ 0 0 53 -4,-2.7 -1,-0.3 1,-0.3 -2,-0.2 0.792 105.3 49.2 -57.8 -27.4 8.0 -39.4 13.6 16 21 A K T << S+ 0 0 166 -3,-1.2 -1,-0.3 -4,-0.6 -2,-0.2 0.342 79.5 139.9 -97.0 3.5 8.8 -38.5 17.3 17 22 A T < - 0 0 44 -3,-1.5 -3,-0.1 -4,-0.1 3,-0.0 -0.195 63.0-101.7 -50.6 133.8 8.1 -34.8 16.9 18 23 A S - 0 0 62 1,-0.1 2,-0.5 0, 0.0 -1,-0.1 -0.325 34.1-118.2 -59.0 138.0 6.2 -33.4 19.9 19 24 A L - 0 0 62 103,-0.1 2,-0.4 -3,-0.1 103,-0.2 -0.694 36.8-176.2 -81.0 124.4 2.5 -32.9 19.4 20 25 A R > - 0 0 158 -2,-0.5 3,-2.3 -3,-0.0 92,-0.3 -0.984 33.9 -95.6-128.6 135.3 1.6 -29.3 19.7 21 26 A K T 3 S+ 0 0 142 -2,-0.4 92,-0.2 1,-0.3 3,-0.1 -0.132 107.8 13.6 -49.1 126.9 -1.9 -27.7 19.6 22 27 A G T 3 S+ 0 0 39 90,-2.7 -1,-0.3 1,-0.3 91,-0.1 0.268 91.1 133.2 92.1 -12.4 -2.8 -26.4 16.1 23 28 A D < - 0 0 68 -3,-2.3 89,-2.5 88,-0.1 2,-0.5 -0.347 54.1-124.1 -67.6 153.1 0.1 -28.1 14.3 24 29 A T E -A 111 0A 38 87,-0.2 65,-0.9 -3,-0.1 2,-0.3 -0.873 27.4-176.1-103.4 130.2 -0.7 -29.9 11.0 25 30 A W E -AB 110 88A 10 85,-3.0 85,-2.8 -2,-0.5 2,-0.4 -0.827 14.1-136.8-119.2 164.0 0.2 -33.6 10.5 26 31 A Y E -AB 109 87A 40 61,-3.1 61,-2.2 -2,-0.3 2,-0.3 -0.949 9.3-129.0-127.8 138.7 -0.1 -35.8 7.5 27 32 A L E - B 0 86A 0 81,-2.1 81,-0.4 -2,-0.4 2,-0.4 -0.667 19.2-169.8 -84.5 139.7 -1.3 -39.3 6.9 28 33 A V E - B 0 85A 0 57,-2.3 57,-2.2 -2,-0.3 34,-0.1 -0.995 31.8-111.1-127.9 124.7 0.8 -41.8 5.0 29 34 A D E > - B 0 84A 7 -2,-0.4 4,-2.5 55,-0.2 3,-0.3 -0.280 21.6-135.0 -52.8 130.6 -0.7 -45.2 3.9 30 35 A S H > S+ 0 0 18 53,-2.2 4,-2.3 1,-0.2 -1,-0.2 0.757 103.4 61.3 -62.9 -25.4 1.1 -47.9 5.9 31 36 A R H > S+ 0 0 154 52,-0.4 4,-1.4 2,-0.2 -1,-0.2 0.943 108.9 40.5 -67.0 -45.6 1.4 -50.0 2.7 32 37 A W H > S+ 0 0 17 -3,-0.3 4,-2.3 29,-0.3 3,-0.3 0.943 116.2 51.6 -62.9 -46.9 3.6 -47.3 1.1 33 38 A F H X S+ 0 0 9 -4,-2.5 4,-2.7 1,-0.2 -2,-0.2 0.852 103.8 57.1 -63.2 -35.2 5.4 -46.7 4.4 34 39 A K H X S+ 0 0 111 -4,-2.3 4,-2.0 2,-0.2 -1,-0.2 0.894 108.3 47.3 -62.7 -39.1 6.2 -50.4 4.8 35 40 A Q H X S+ 0 0 59 -4,-1.4 4,-2.7 -3,-0.3 -2,-0.2 0.932 110.8 51.8 -67.0 -44.8 8.0 -50.4 1.4 36 41 A W H X S+ 0 0 0 -4,-2.3 4,-2.3 1,-0.2 6,-0.2 0.920 107.9 52.9 -54.7 -46.6 9.8 -47.2 2.4 37 42 A K H X>S+ 0 0 70 -4,-2.7 5,-2.6 1,-0.2 4,-0.9 0.922 111.1 45.5 -57.6 -45.7 11.0 -48.9 5.6 38 43 A K H ><5S+ 0 0 59 -4,-2.0 3,-0.7 1,-0.2 -1,-0.2 0.932 112.0 52.8 -61.3 -44.1 12.4 -51.9 3.7 39 44 A Y H 3<5S+ 0 0 35 -4,-2.7 12,-2.6 16,-0.4 -2,-0.2 0.839 117.3 35.7 -63.4 -37.0 14.0 -49.6 1.2 40 45 A V H 3<5S- 0 0 0 -4,-2.3 -1,-0.2 10,-0.2 -2,-0.2 0.423 112.0-112.1 -98.2 1.5 15.9 -47.5 3.8 41 46 A G T X<5 + 0 0 0 -4,-0.9 3,-0.9 -3,-0.7 2,-0.4 0.828 51.3 173.8 73.0 33.4 16.6 -50.3 6.3 42 47 A F T 3 + 0 0 83 1,-0.1 3,-1.2 2,-0.1 -5,-0.0 0.754 51.8 155.4 57.6 25.7 19.1 -54.9 5.8 48 53 A Y T 3 S+ 0 0 189 1,-0.3 -1,-0.1 3,-0.0 -10,-0.0 0.825 72.2 29.5 -59.4 -36.3 18.3 -57.6 3.3 49 54 A Q T > S+ 0 0 66 -11,-0.1 3,-2.2 2,-0.1 -1,-0.3 0.350 85.7 136.5-105.0 6.2 16.1 -55.4 1.0 50 55 A M T < S- 0 0 51 -3,-1.2 -11,-0.2 1,-0.3 -10,-0.2 -0.311 81.7 -0.1 -59.1 130.2 17.8 -52.1 1.7 51 56 A G T 3 S+ 0 0 29 -12,-2.6 -1,-0.3 1,-0.2 2,-0.2 0.420 96.8 145.1 74.8 -0.8 18.3 -50.1 -1.5 52 57 A D X> - 0 0 67 -3,-2.2 3,-1.8 -14,-0.2 4,-0.6 -0.496 54.9-136.0 -79.8 137.6 16.7 -52.8 -3.6 53 58 A Q G >4 S+ 0 0 149 1,-0.3 3,-0.8 -2,-0.2 -1,-0.1 0.799 101.2 69.8 -54.3 -31.6 14.6 -51.9 -6.6 54 59 A N G 34 S+ 0 0 132 1,-0.2 -1,-0.3 -15,-0.0 -15,-0.0 0.721 108.7 33.4 -64.4 -21.9 12.0 -54.5 -5.6 55 60 A V G <4 S+ 0 0 3 -3,-1.8 -16,-0.4 -6,-0.2 -1,-0.2 0.338 77.6 133.3-117.2 5.9 11.0 -52.4 -2.6 56 61 A Y << - 0 0 101 -3,-0.8 -20,-0.1 -4,-0.6 -21,-0.0 -0.381 52.0-145.1 -52.8 125.5 11.5 -48.9 -4.0 57 62 A P - 0 0 20 0, 0.0 -1,-0.2 0, 0.0 -21,-0.1 0.707 21.2-154.5 -80.8 -15.3 8.2 -47.3 -2.8 58 63 A G - 0 0 13 -23,-0.1 3,-0.1 2,-0.1 44,-0.1 -0.159 51.5 -10.0 70.4-172.0 7.5 -45.0 -5.8 59 64 A P S S- 0 0 54 0, 0.0 42,-0.2 0, 0.0 41,-0.2 -0.254 89.0 -91.3 -57.8 142.4 5.4 -41.9 -5.5 60 65 A I B -e 101 0B 0 40,-2.8 42,-2.6 35,-0.1 2,-0.5 -0.356 49.0-168.8 -55.6 128.9 3.5 -41.5 -2.2 61 66 A D + 0 0 50 40,-0.1 -29,-0.3 -32,-0.1 3,-0.3 -0.923 25.9 162.0-132.9 105.6 0.1 -43.1 -2.8 62 67 A N > + 0 0 0 -2,-0.5 3,-2.3 1,-0.2 4,-0.4 0.183 43.7 113.9-103.0 13.4 -2.7 -42.6 -0.3 63 68 A S G > + 0 0 64 1,-0.3 3,-1.4 2,-0.2 -1,-0.2 0.822 70.0 63.1 -56.4 -32.9 -5.5 -43.6 -2.6 64 69 A G G 3 S+ 0 0 20 -3,-0.3 -1,-0.3 1,-0.3 -2,-0.1 0.636 100.4 53.3 -67.1 -15.2 -6.1 -46.7 -0.5 65 70 A L G < S+ 0 0 2 -3,-2.3 10,-3.0 2,-0.1 2,-0.3 0.519 99.2 82.9 -92.5 -8.7 -7.1 -44.5 2.4 66 71 A L B < S-F 74 0C 31 -3,-1.4 8,-0.2 -4,-0.4 2,-0.1 -0.721 70.9-131.0-107.2 147.0 -9.6 -42.5 0.4 67 72 A K - 0 0 91 6,-3.0 5,-0.1 -2,-0.3 -2,-0.1 -0.455 47.4 -83.8 -78.3 162.3 -13.3 -43.0 -0.5 68 73 A D S S+ 0 0 103 -2,-0.1 5,-0.3 4,-0.1 -1,-0.2 -0.216 82.6 67.5 -65.6 159.3 -14.3 -42.5 -4.2 69 74 A G S S- 0 0 61 1,-0.1 -3,-0.0 3,-0.1 -2,-0.0 -0.315 86.4 -83.5 116.3 163.8 -15.0 -39.0 -5.6 70 75 A D S S+ 0 0 109 1,-0.2 -1,-0.1 -2,-0.1 -2,-0.0 0.865 121.8 57.7 -71.5 -38.1 -13.4 -35.7 -6.4 71 76 A A S S- 0 0 103 -3,-0.1 -1,-0.2 1,-0.0 -2,-0.1 0.845 94.5-150.6 -62.6 -35.0 -13.7 -34.4 -2.8 72 77 A Q - 0 0 44 -4,-0.1 2,-0.2 1,-0.1 -3,-0.1 0.987 15.4-168.1 62.6 67.4 -11.6 -37.4 -1.6 73 78 A S - 0 0 64 -5,-0.3 -6,-3.0 1,-0.1 2,-0.2 -0.523 27.9 -98.8 -82.2 153.8 -12.9 -37.9 1.9 74 79 A L B -F 66 0C 10 -8,-0.2 -8,-0.2 -2,-0.2 -1,-0.1 -0.492 38.0-109.3 -74.1 136.7 -11.0 -40.3 4.2 75 80 A K - 0 0 82 -10,-3.0 3,-0.5 -2,-0.2 2,-0.1 -0.288 38.5-114.4 -56.1 149.8 -12.3 -43.8 4.7 76 81 A E S S+ 0 0 81 1,-0.2 -1,-0.1 -10,-0.0 51,-0.0 -0.414 88.6 31.4 -84.2 163.4 -13.8 -44.5 8.1 77 82 A H S S+ 0 0 166 1,-0.2 -1,-0.2 -2,-0.1 2,-0.2 0.629 73.9 155.8 67.2 19.1 -12.5 -46.9 10.7 78 83 A L - 0 0 24 -3,-0.5 2,-0.4 -13,-0.1 -1,-0.2 -0.522 31.8-142.7 -74.2 146.4 -8.8 -46.5 9.9 79 84 A I >> - 0 0 97 -2,-0.2 4,-3.0 1,-0.0 5,-1.1 -0.931 17.6-108.8-119.4 132.0 -6.4 -47.3 12.7 80 85 A D B 45S+c 84 0A 73 -2,-0.4 2,-1.7 1,-0.2 5,-0.2 -0.289 101.6 5.1 -58.2 140.0 -3.1 -45.5 13.5 81 86 A E T 45S+ 0 0 131 3,-2.7 -1,-0.2 1,-0.2 4,-0.0 -0.346 127.7 63.2 78.4 -50.5 0.0 -47.6 12.7 82 87 A L T 45S+ 0 0 117 -2,-1.7 -2,-0.2 1,-0.1 -1,-0.2 0.961 123.3 10.2 -68.1 -52.6 -2.0 -50.4 11.1 83 88 A D T <5S+ 0 0 50 -4,-3.0 -53,-2.2 1,-0.3 -52,-0.4 0.738 134.9 4.6-101.9 -29.5 -3.5 -48.4 8.2 84 89 A Y E < -Bc 29 80A 13 -5,-1.1 -3,-2.7 -55,-0.3 2,-0.3 -0.965 57.2-142.0-148.5 161.3 -1.6 -45.2 8.3 85 90 A I E -B 28 0A 7 -57,-2.2 -57,-2.3 -2,-0.3 2,-0.4 -0.870 22.8-126.5-120.1 163.1 1.3 -43.4 10.0 86 91 A L E +B 27 0A 21 -2,-0.3 -59,-0.2 -59,-0.2 -2,-0.0 -0.928 24.3 178.3-115.3 133.6 1.5 -39.7 10.9 87 92 A L E -B 26 0A 0 -61,-2.2 -61,-3.1 -2,-0.4 -72,-0.1 -0.969 26.9-119.6-127.6 149.5 4.2 -37.2 10.1 88 93 A P E >> -B 25 0A 12 0, 0.0 4,-2.5 0, 0.0 3,-0.6 -0.264 46.8 -86.9 -75.0 171.9 4.6 -33.5 10.8 89 94 A T H 3> S+ 0 0 58 -65,-0.9 4,-2.9 1,-0.2 5,-0.2 0.870 128.2 50.7 -46.6 -48.5 4.8 -31.0 8.0 90 95 A E H 3> S+ 0 0 117 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.878 111.4 48.3 -63.8 -36.6 8.6 -31.3 7.6 91 96 A G H <> S+ 0 0 0 -3,-0.6 4,-2.3 2,-0.2 -1,-0.2 0.922 113.0 46.9 -68.6 -45.0 8.4 -35.1 7.4 92 97 A W H X S+ 0 0 8 -4,-2.5 4,-2.5 1,-0.2 5,-0.2 0.946 112.0 51.3 -59.2 -47.7 5.7 -35.0 4.8 93 98 A N H X S+ 0 0 89 -4,-2.9 4,-2.4 -5,-0.3 -1,-0.2 0.871 108.7 51.4 -61.9 -36.8 7.6 -32.4 2.8 94 99 A K H X S+ 0 0 49 -4,-1.9 4,-2.4 -5,-0.2 -1,-0.2 0.948 109.8 48.6 -65.5 -47.5 10.7 -34.6 2.9 95 100 A L H X S+ 0 0 0 -4,-2.3 4,-2.6 1,-0.2 5,-0.5 0.916 112.7 48.7 -57.1 -43.3 8.9 -37.7 1.6 96 101 A V H X S+ 0 0 43 -4,-2.5 4,-2.3 1,-0.2 -1,-0.2 0.920 111.3 50.0 -63.1 -43.1 7.3 -35.6 -1.2 97 102 A S H < S+ 0 0 98 -4,-2.4 -1,-0.2 -5,-0.2 -2,-0.2 0.894 117.3 40.7 -61.3 -39.8 10.7 -34.1 -2.1 98 103 A W H < S+ 0 0 27 -4,-2.4 -2,-0.2 -5,-0.1 -1,-0.2 0.835 136.2 11.4 -78.1 -36.4 12.3 -37.6 -2.2 99 104 A Y H < S- 0 0 8 -4,-2.6 -3,-0.2 -5,-0.2 -2,-0.2 0.581 97.1-124.8-119.0 -14.8 9.6 -39.6 -3.9 100 105 A T < - 0 0 79 -4,-2.3 -40,-2.8 -5,-0.5 2,-0.5 0.182 28.2 -91.3 70.0 157.2 7.0 -37.2 -5.3 101 106 A L B -e 60 0B 34 -42,-0.2 -40,-0.1 -5,-0.1 3,-0.1 -0.877 54.4 -93.0 -94.8 134.0 3.3 -37.3 -4.4 102 107 A M > - 0 0 67 -42,-2.6 3,-2.0 -2,-0.5 -40,-0.1 -0.214 54.9 -98.9 -49.0 127.6 1.3 -39.4 -6.9 103 108 A E T 3 S+ 0 0 192 1,-0.2 -1,-0.1 -3,-0.0 3,-0.1 -0.220 106.1 22.6 -57.1 135.1 0.1 -37.0 -9.5 104 109 A G T 3 S+ 0 0 84 1,-0.3 -1,-0.2 -3,-0.1 2,-0.2 0.236 98.7 112.9 95.4 -12.3 -3.5 -35.9 -9.0 105 110 A Q < - 0 0 29 -3,-2.0 -1,-0.3 -4,-0.1 -4,-0.1 -0.630 54.8-145.3 -93.8 150.5 -3.6 -36.7 -5.3 106 111 A E - 0 0 145 -2,-0.2 -44,-0.1 -3,-0.1 -4,-0.1 -0.837 28.6-101.1-107.0 152.1 -3.9 -34.2 -2.4 107 112 A P - 0 0 52 0, 0.0 2,-0.8 0, 0.0 -79,-0.1 -0.314 28.9-125.4 -62.7 155.0 -2.2 -34.5 1.0 108 113 A I - 0 0 10 -81,-0.4 -81,-2.1 2,-0.0 2,-0.4 -0.876 36.4-172.9-105.2 97.4 -4.3 -35.8 3.8 109 114 A A E +A 26 0A 43 -2,-0.8 2,-0.3 -83,-0.2 -83,-0.2 -0.753 9.6 175.3 -99.4 137.1 -3.9 -33.1 6.5 110 115 A R E -A 25 0A 67 -85,-2.8 -85,-3.0 -2,-0.4 2,-0.3 -0.959 23.0-121.7-136.7 156.2 -5.2 -33.2 10.1 111 116 A K E -AD 24 125A 110 14,-0.5 14,-3.0 -2,-0.3 2,-0.4 -0.724 16.3-121.1-103.6 147.9 -4.8 -31.0 13.1 112 117 A V E + D 0 124A 2 -89,-2.5 -90,-2.7 -2,-0.3 2,-0.3 -0.701 38.0 178.2 -79.2 129.1 -3.4 -31.5 16.6 113 118 A V E - D 0 123A 15 10,-2.8 10,-2.0 -2,-0.4 2,-0.5 -0.917 36.2-104.0-127.9 157.9 -6.0 -30.8 19.3 114 119 A E E - D 0 122A 80 -2,-0.3 2,-0.3 8,-0.2 8,-0.2 -0.729 48.4-175.0 -78.1 126.2 -6.0 -30.9 23.0 115 120 A Q E + D 0 121A 29 6,-3.1 6,-2.3 -2,-0.5 2,-0.1 -0.829 26.9 73.5-125.0 161.1 -8.0 -34.0 24.0 116 121 A G S S- 0 0 17 -2,-0.3 2,-0.9 4,-0.2 79,-0.1 -0.362 83.2 -70.8 120.5 159.8 -9.2 -35.6 27.2 117 122 A M S S- 0 0 114 -2,-0.1 2,-2.8 2,-0.1 78,-0.1 -0.800 102.6 -45.7 -88.2 103.6 -11.9 -35.0 29.8 118 123 A F S S+ 0 0 121 -2,-0.9 2,-0.6 74,-0.0 -1,-0.1 -0.282 131.9 81.4 65.2 -53.5 -10.6 -31.8 31.6 119 124 A V S S- 0 0 108 -2,-2.8 2,-0.3 76,-0.0 -2,-0.1 -0.744 80.0-152.6 -81.0 120.1 -7.1 -33.3 31.8 120 125 A K + 0 0 57 -2,-0.6 2,-0.3 -4,-0.1 -4,-0.2 -0.759 29.5 165.0-109.6 142.5 -5.6 -32.6 28.4 121 126 A H E -D 115 0A 139 -6,-2.3 -6,-3.1 -2,-0.3 2,-0.1 -0.976 41.4-101.9-141.0 152.6 -2.9 -34.1 26.1 122 127 A C E +D 114 0A 38 -2,-0.3 2,-0.3 -103,-0.2 -8,-0.2 -0.401 41.5 169.0 -75.7 149.7 -2.4 -33.4 22.4 123 128 A K E -D 113 0A 104 -10,-2.0 -10,-2.8 -2,-0.1 2,-0.5 -0.969 41.0-109.0-155.0 141.0 -3.6 -35.8 19.7 124 129 A V E -D 112 0A 7 -2,-0.3 2,-1.2 -12,-0.3 -12,-0.3 -0.657 34.7-137.3 -71.4 123.6 -3.9 -35.6 15.9 125 130 A E E +D 111 0A 16 -14,-3.0 -14,-0.5 -2,-0.5 3,-0.1 -0.714 36.2 163.6 -88.1 94.2 -7.6 -35.4 15.3 126 131 A V + 0 0 9 -2,-1.2 2,-0.4 1,-0.2 -1,-0.2 0.886 67.6 33.1 -78.9 -40.0 -8.0 -37.8 12.4 127 132 A Y S S- 0 0 62 -3,-0.2 -1,-0.2 -17,-0.0 2,-0.1 -0.968 76.9-138.3-120.6 133.7 -11.8 -38.2 12.8 128 133 A L - 0 0 79 -2,-0.4 2,-0.6 -3,-0.1 20,-0.2 -0.301 30.0-104.6 -75.5 169.2 -14.3 -35.6 14.0 129 134 A T E -G 147 0D 5 18,-3.2 18,-2.7 -2,-0.1 2,-0.5 -0.877 26.9-142.4-104.4 122.0 -17.1 -36.5 16.4 130 135 A E E -G 146 0D 64 -2,-0.6 71,-2.8 16,-0.2 72,-0.5 -0.705 19.1-170.8 -85.3 128.8 -20.6 -36.8 15.0 131 136 A L E -Gh 145 202D 0 14,-2.9 14,-1.9 -2,-0.5 2,-0.5 -0.930 20.7-130.0-118.5 146.1 -23.4 -35.6 17.3 132 137 A K E -Gh 144 203D 85 70,-3.0 72,-3.1 -2,-0.4 2,-0.4 -0.834 28.1-163.6 -95.8 126.4 -27.1 -36.0 16.8 133 138 A L E +Gh 143 204D 0 10,-2.8 10,-2.6 -2,-0.5 2,-0.3 -0.907 17.2 151.6-120.0 133.4 -28.9 -32.7 17.2 134 139 A C E - h 0 205D 1 70,-1.9 72,-2.6 -2,-0.4 2,-0.4 -0.980 38.5-108.2-154.0 167.4 -32.6 -32.0 17.8 135 140 A E E > - h 0 206D 42 3,-0.5 3,-2.4 6,-0.4 6,-0.2 -0.832 41.2-104.7-100.8 135.7 -35.3 -29.8 19.2 136 141 A N T 3 S+ 0 0 30 70,-3.2 72,-0.1 -2,-0.4 82,-0.1 -0.285 109.9 25.9 -51.5 133.3 -37.4 -30.7 22.3 137 142 A G T 3 S+ 0 0 56 70,-0.0 -1,-0.3 79,-0.0 3,-0.1 0.159 124.2 53.2 92.8 -19.6 -40.8 -31.7 21.2 138 143 A N X + 0 0 80 -3,-2.4 3,-2.2 3,-0.1 -3,-0.5 -0.232 59.7 145.0-136.5 45.4 -39.7 -32.8 17.7 139 144 A M T 3 + 0 0 34 1,-0.3 -3,-0.1 -5,-0.2 -1,-0.1 0.661 63.7 73.9 -62.5 -15.6 -36.9 -35.2 18.7 140 145 A N T 3 S+ 0 0 145 1,-0.2 2,-1.2 -5,-0.1 -1,-0.3 0.747 81.9 74.6 -66.0 -26.0 -37.8 -37.3 15.7 141 146 A N S < S+ 0 0 78 -3,-2.2 2,-0.4 -6,-0.2 -6,-0.4 -0.716 72.1 178.4 -93.8 88.6 -36.2 -34.7 13.4 142 147 A V - 0 0 62 -2,-1.2 2,-0.4 -8,-0.1 -8,-0.2 -0.770 15.2-168.8-100.3 133.4 -32.5 -35.3 14.0 143 148 A V E -G 133 0D 31 -10,-2.6 -10,-2.8 -2,-0.4 2,-0.4 -0.979 13.1-147.3-117.9 130.0 -29.7 -33.5 12.2 144 149 A T E +G 132 0D 59 -2,-0.4 2,-0.3 -12,-0.2 -12,-0.2 -0.788 19.3 172.7 -99.2 141.6 -26.1 -34.8 12.5 145 150 A R E -G 131 0D 99 -14,-1.9 -14,-2.9 -2,-0.4 2,-0.4 -0.983 27.3-124.8-140.0 153.5 -23.0 -32.6 12.5 146 151 A R E -G 130 0D 162 -2,-0.3 2,-0.3 -16,-0.2 -16,-0.2 -0.833 30.7-179.7-101.3 135.9 -19.3 -33.3 13.1 147 152 A F E -G 129 0D 13 -18,-2.7 -18,-3.2 -2,-0.4 2,-0.2 -0.897 28.5-109.1-131.4 157.8 -17.4 -31.4 15.7 148 153 A S > - 0 0 18 -2,-0.3 3,-1.9 -20,-0.2 45,-0.4 -0.608 28.7-121.2 -81.7 148.0 -13.9 -31.3 17.1 149 154 A K T 3 S+ 0 0 24 1,-0.3 45,-1.1 -2,-0.2 46,-0.3 0.726 116.3 55.0 -57.4 -22.8 -13.2 -32.7 20.6 150 155 A A T 3 S+ 0 0 38 42,-0.1 -1,-0.3 43,-0.1 2,-0.2 0.495 81.2 111.1 -92.5 -4.7 -11.9 -29.2 21.4 151 156 A D < - 0 0 49 -3,-1.9 42,-2.1 1,-0.1 43,-0.2 -0.483 66.7-127.2 -66.8 140.0 -15.2 -27.5 20.4 152 157 A T B > -K 192 0E 37 40,-0.3 4,-2.3 -2,-0.2 40,-0.3 -0.437 17.0-112.3 -87.4 161.9 -17.1 -26.0 23.3 153 158 A I H > S+ 0 0 1 38,-2.5 4,-3.1 35,-0.3 5,-0.2 0.883 120.3 58.1 -56.7 -38.7 -20.7 -26.5 24.3 154 159 A D H > S+ 0 0 60 35,-2.3 4,-2.2 37,-0.3 -1,-0.2 0.922 106.7 47.7 -57.0 -44.3 -21.2 -22.8 23.4 155 160 A T H > S+ 0 0 62 34,-0.3 4,-1.8 2,-0.2 -2,-0.2 0.925 113.5 47.0 -63.1 -44.7 -20.0 -23.5 19.9 156 161 A I H X S+ 0 0 0 -4,-2.3 4,-2.5 2,-0.2 -2,-0.2 0.931 111.7 50.2 -63.0 -45.8 -22.2 -26.6 19.5 157 162 A E H X S+ 0 0 33 -4,-3.1 4,-2.6 1,-0.2 -1,-0.2 0.889 108.0 53.3 -63.9 -38.6 -25.3 -24.8 20.9 158 163 A K H X S+ 0 0 128 -4,-2.2 4,-1.9 -5,-0.2 -1,-0.2 0.898 109.8 48.5 -62.2 -38.5 -24.8 -21.9 18.4 159 164 A E H X S+ 0 0 51 -4,-1.8 4,-2.7 2,-0.2 -2,-0.2 0.916 110.5 50.6 -68.5 -41.6 -24.7 -24.4 15.5 160 165 A I H X S+ 0 0 0 -4,-2.5 4,-2.3 1,-0.2 -2,-0.2 0.924 109.6 50.8 -59.4 -44.3 -27.8 -26.1 16.8 161 166 A R H <>S+ 0 0 42 -4,-2.6 5,-2.5 1,-0.2 -1,-0.2 0.889 111.0 49.2 -62.6 -37.7 -29.6 -22.7 17.0 162 167 A K H ><5S+ 0 0 160 -4,-1.9 3,-1.4 3,-0.2 -2,-0.2 0.956 110.2 50.3 -64.1 -50.4 -28.5 -21.9 13.4 163 168 A I H 3<5S+ 0 0 35 -4,-2.7 -2,-0.2 1,-0.3 -1,-0.2 0.897 116.3 40.2 -54.6 -45.6 -29.7 -25.3 12.1 164 169 A F T 3<5S- 0 0 25 -4,-2.3 -1,-0.3 -5,-0.2 -2,-0.2 0.249 110.4-118.4 -95.6 14.6 -33.2 -25.0 13.7 165 170 A S T < 5 + 0 0 105 -3,-1.4 -3,-0.2 1,-0.2 -4,-0.1 0.830 48.4 171.3 56.5 37.5 -33.5 -21.2 12.9 166 171 A I < - 0 0 11 -5,-2.5 -1,-0.2 -6,-0.2 -2,-0.1 -0.684 32.0-122.6 -80.5 123.9 -33.8 -20.2 16.5 167 172 A P > - 0 0 47 0, 0.0 3,-1.7 0, 0.0 -1,-0.1 -0.274 14.7-114.8 -71.7 154.6 -33.6 -16.4 16.7 168 173 A D T 3 S+ 0 0 153 1,-0.3 -2,-0.0 3,-0.0 -7,-0.0 0.819 113.0 59.2 -54.0 -36.5 -31.0 -14.5 18.7 169 174 A E T 3 S+ 0 0 158 2,-0.1 2,-0.4 0, 0.0 -1,-0.3 0.623 88.6 89.7 -74.4 -12.6 -33.6 -13.0 21.1 170 175 A K S < S- 0 0 32 -3,-1.7 2,-0.3 38,-0.0 40,-0.1 -0.720 72.7-136.5 -89.4 132.3 -34.8 -16.5 22.2 171 176 A E - 0 0 104 -2,-0.4 38,-2.4 38,-0.1 2,-0.3 -0.615 23.7-167.2 -82.7 144.7 -33.1 -18.1 25.2 172 177 A T E -I 208 0D 23 -2,-0.3 2,-0.4 36,-0.2 36,-0.2 -0.913 17.1-155.9-129.1 158.0 -32.2 -21.8 24.9 173 178 A R E -I 207 0D 124 34,-2.1 34,-2.3 -2,-0.3 2,-0.4 -0.998 17.3-148.6-128.6 134.3 -31.1 -24.6 27.2 174 179 A L E -I 206 0D 4 12,-0.4 12,-2.8 -2,-0.4 2,-0.3 -0.844 14.1-169.5-108.1 140.3 -29.2 -27.6 25.8 175 180 A W E -IJ 205 185D 46 30,-2.2 30,-2.5 -2,-0.4 2,-0.4 -0.932 15.7-139.5-129.1 149.7 -29.4 -31.2 27.2 176 181 A N E -IJ 204 184D 8 8,-3.0 8,-2.4 -2,-0.3 2,-1.3 -0.872 17.2-135.1-100.4 137.6 -27.6 -34.5 26.8 177 182 A K E > - J 0 183D 32 26,-2.3 3,-1.6 -2,-0.4 26,-0.4 -0.776 33.2-154.4 -86.8 90.0 -29.5 -37.8 26.6 178 183 A Y E >> S- J 0 182D 126 4,-2.5 4,-2.0 -2,-1.3 3,-1.8 -0.519 74.4 -2.6 -74.3 131.4 -27.1 -39.5 29.0 179 184 A M T 34 S- 0 0 139 1,-0.3 -1,-0.3 -2,-0.3 23,-0.0 0.773 122.0 -77.1 55.2 28.5 -26.9 -43.3 28.5 180 185 A S T <4 S+ 0 0 110 -3,-1.6 -1,-0.3 2,-0.1 -2,-0.2 0.845 129.3 74.8 53.0 35.1 -29.6 -42.6 25.9 181 186 A N T <4 S+ 0 0 106 -3,-1.8 2,-0.4 1,-0.4 -2,-0.2 0.597 77.9 45.0-140.8 -69.1 -31.8 -42.3 29.0 182 187 A T E < S-J 178 0D 53 -4,-2.0 -4,-2.5 1,-0.0 2,-0.5 -0.776 70.5-121.6-100.6 141.1 -31.8 -39.3 31.3 183 188 A F E -J 177 0D 21 -2,-0.4 -6,-0.2 -6,-0.2 35,-0.0 -0.673 34.6-176.9 -73.6 126.5 -31.8 -35.7 30.4 184 189 A E E -J 176 0D 86 -8,-2.4 -8,-3.0 -2,-0.5 2,-0.1 -0.990 27.6-109.7-128.5 137.9 -28.7 -34.0 31.8 185 190 A P E -J 175 0D 59 0, 0.0 2,-1.0 0, 0.0 -10,-0.2 -0.420 10.3-153.8 -76.1 138.4 -28.1 -30.3 31.5 186 191 A L + 0 0 20 -12,-2.8 -12,-0.4 -2,-0.1 -11,-0.0 -0.706 44.1 145.4-100.1 75.4 -25.3 -28.9 29.3 187 192 A N + 0 0 131 -2,-1.0 -1,-0.1 1,-0.1 -12,-0.0 0.217 41.9 81.5-105.3 12.2 -25.1 -25.9 31.5 188 193 A K > - 0 0 86 1,-0.1 3,-1.4 -3,-0.1 -35,-0.3 -0.890 57.8-171.6-120.1 96.3 -21.4 -25.2 31.3 189 194 A P T 3 S+ 0 0 73 0, 0.0 -35,-2.3 0, 0.0 -34,-0.3 0.724 78.7 55.1 -68.5 -22.4 -20.7 -23.3 28.1 190 195 A D T 3 S+ 0 0 114 -37,-0.2 2,-0.2 -38,-0.1 -2,-0.0 0.432 81.5 106.4 -93.9 0.2 -16.9 -23.4 28.2 191 196 A S S < S- 0 0 6 -3,-1.4 -38,-2.5 1,-0.1 -37,-0.3 -0.546 72.3-124.4 -68.5 142.8 -16.6 -27.1 28.5 192 197 A T B > -K 152 0E 16 -40,-0.3 4,-2.0 -2,-0.2 -40,-0.3 -0.398 30.6-101.4 -78.2 166.2 -15.4 -28.9 25.4 193 198 A I T 4>S+ 0 0 0 -42,-2.1 5,-2.8 -45,-0.4 -43,-0.1 0.875 126.5 46.8 -59.7 -33.4 -17.6 -31.7 24.1 194 199 A Q T >45S+ 0 0 21 -45,-1.1 3,-1.4 3,-0.2 -1,-0.2 0.870 105.7 56.9 -77.2 -35.4 -15.2 -34.2 25.6 195 200 A D T 345S+ 0 0 19 -46,-0.3 -1,-0.2 1,-0.3 -2,-0.2 0.895 110.3 48.0 -52.6 -40.1 -15.1 -32.4 29.0 196 201 A A T 3<5S- 0 0 30 -4,-2.0 -1,-0.3 2,-0.1 -2,-0.2 0.423 119.2-115.5 -84.7 -2.0 -18.9 -32.8 28.9 197 202 A G T < 5 + 0 0 26 -3,-1.4 2,-0.6 1,-0.2 -3,-0.2 0.743 59.6 153.4 77.8 26.9 -18.6 -36.5 28.0 198 203 A L < + 0 0 0 -5,-2.8 -1,-0.2 -6,-0.2 2,-0.2 -0.800 15.1 170.9 -98.7 121.7 -20.2 -36.4 24.5 199 204 A Y > - 0 0 99 -2,-0.6 3,-2.3 1,-0.2 -70,-0.0 -0.569 43.7 -41.0-122.4 179.8 -19.1 -39.0 22.1 200 205 A Q T 3 S+ 0 0 114 1,-0.3 -69,-0.2 -2,-0.2 -1,-0.2 -0.109 126.0 10.6 -46.3 128.5 -20.1 -40.3 18.6 201 206 A G T 3 S+ 0 0 26 -71,-2.8 -1,-0.3 1,-0.3 -70,-0.2 0.476 84.6 160.2 83.3 2.8 -23.9 -40.5 18.2 202 207 A Q E < -h 131 0D 32 -3,-2.3 -70,-3.0 -72,-0.5 2,-0.6 -0.344 37.1-132.6 -58.7 135.2 -24.7 -38.6 21.3 203 208 A V E -h 132 0D 38 -26,-0.4 -26,-2.3 -72,-0.2 2,-0.4 -0.833 23.1-170.7 -95.7 119.0 -28.2 -37.1 21.2 204 209 A L E -hI 133 176D 0 -72,-3.1 -70,-1.9 -2,-0.6 2,-0.5 -0.909 4.0-160.4-109.7 137.4 -28.4 -33.5 22.2 205 210 A V E -hI 134 175D 0 -30,-2.5 -30,-2.2 -2,-0.4 2,-0.4 -0.964 2.1-161.5-124.2 122.4 -31.8 -31.8 22.7 206 211 A I E -hI 135 174D 1 -72,-2.6 -70,-3.2 -2,-0.5 2,-0.3 -0.803 6.0-169.0-102.9 142.3 -32.3 -28.0 22.7 207 212 A E E - I 0 173D 8 -34,-2.3 -34,-2.1 -2,-0.4 2,-0.4 -0.969 12.6-138.7-128.2 153.2 -35.3 -26.2 24.1 208 213 A Q E - I 0 172D 61 -2,-0.3 -36,-0.2 -36,-0.2 2,-0.1 -0.847 27.1-108.7-108.1 141.8 -36.5 -22.6 23.8 209 214 A K - 0 0 52 -38,-2.4 6,-0.2 -2,-0.4 -38,-0.1 -0.412 38.4-112.8 -66.1 140.6 -37.9 -20.5 26.7 210 215 A N > - 0 0 68 4,-3.0 3,-1.6 1,-0.1 -39,-0.1 -0.304 23.7-112.1 -68.5 159.4 -41.6 -19.9 26.4 211 216 A E T 3 S+ 0 0 167 1,-0.3 -1,-0.1 2,-0.1 -2,-0.1 0.838 117.2 59.0 -61.3 -32.5 -42.9 -16.3 25.8 212 217 A D T 3 S- 0 0 124 2,-0.1 -1,-0.3 1,-0.1 3,-0.1 0.419 122.6-103.3 -81.8 2.7 -44.3 -16.3 29.3 213 218 A G S < S+ 0 0 41 -3,-1.6 2,-0.1 1,-0.4 -2,-0.1 0.282 84.3 117.7 98.2 -11.0 -40.9 -16.9 30.9 214 219 A T - 0 0 71 -5,-0.1 -4,-3.0 1,-0.0 -1,-0.4 -0.443 62.5-121.2 -84.8 162.7 -41.4 -20.6 31.7 215 220 A W - 0 0 61 -6,-0.2 -6,-0.1 -2,-0.1 3,-0.1 -0.899 29.8-110.6-105.8 134.5 -39.3 -23.4 30.3 216 221 A P - 0 0 33 0, 0.0 3,-0.1 0, 0.0 2,-0.1 -0.227 34.5-104.0 -58.6 145.4 -41.0 -26.3 28.3 217 222 A R - 0 0 233 1,-0.1 2,-0.2 -81,-0.0 0, 0.0 -0.376 45.1-101.5 -61.6 149.6 -41.2 -29.8 29.8 218 223 A L - 0 0 36 1,-0.1 2,-0.3 -3,-0.1 -1,-0.1 -0.571 38.0-103.1 -81.7 141.7 -38.7 -32.2 28.3 219 224 A E + 0 0 29 -2,-0.2 2,-0.3 -3,-0.1 -1,-0.1 -0.440 43.5 177.5 -66.9 123.7 -40.0 -34.7 25.7 220 225 A H + 0 0 134 -2,-0.3 2,-0.3 -83,-0.0 -1,-0.0 -0.964 3.3 171.5-127.9 146.9 -40.4 -38.3 26.9 221 226 A H 0 0 145 -2,-0.3 -2,-0.0 0, 0.0 0, 0.0 -0.982 360.0 360.0-148.1 161.0 -41.7 -41.5 25.1 222 227 A H 0 0 246 -2,-0.3 -2,-0.0 0, 0.0 0, 0.0 -0.530 360.0 360.0 -77.6 360.0 -42.0 -45.2 25.7