==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=13-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 01-JUN-04 1THK . COMPND 2 MOLECULE: CARBONIC ANHYDRASE II; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR Z.FISHER,J.A.HERNANDEZ PRADA,C.K.TU,D.DUDA,C.YOSHIOKA,H.AN, . 258 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12088.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 165 64.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 18 7.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 57 22.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 25 9.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 34 13.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 2 2 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A H 0 0 186 0, 0.0 2,-0.3 0, 0.0 8,-0.0 0.000 360.0 360.0 360.0 133.3 13.1 -0.6 6.6 2 4 A H - 0 0 147 0, 0.0 0, 0.0 0, 0.0 0, 0.0 -0.955 360.0 -56.9-162.9 175.9 10.1 0.0 8.9 3 5 A W + 0 0 80 -2,-0.3 2,-0.2 11,-0.1 7,-0.2 -0.239 61.3 133.3 -66.0 151.5 7.7 -1.6 11.4 4 6 A G - 0 0 13 5,-2.3 10,-0.1 2,-0.2 58,-0.1 -0.799 64.6 -84.8-166.1-153.7 5.6 -4.5 10.4 5 7 A Y S S+ 0 0 37 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.112 82.6 111.9-122.9 20.5 4.5 -8.0 11.7 6 8 A G S > S- 0 0 33 4,-0.1 4,-1.5 1,-0.1 3,-0.3 -0.261 83.8 -96.6 -87.0 177.9 7.4 -10.0 10.3 7 9 A K T 4 S+ 0 0 173 1,-0.2 -1,-0.1 2,-0.2 5,-0.0 0.804 123.4 38.6 -64.3 -30.2 10.2 -11.8 12.2 8 10 A H T 4 S+ 0 0 144 1,-0.1 -1,-0.2 5,-0.0 -3,-0.0 0.562 131.3 24.2 -99.9 -9.9 12.6 -8.9 11.7 9 11 A N T 4 S+ 0 0 47 -3,-0.3 -5,-2.3 -6,-0.1 -2,-0.2 0.205 93.7 128.4-137.3 14.0 10.3 -5.9 12.1 10 12 A G S >X S- 0 0 0 -4,-1.5 3,-2.7 -5,-0.2 4,-0.9 0.111 78.8 -76.8 -66.5-179.9 7.5 -7.4 14.3 11 13 A P T 34 S+ 0 0 23 0, 0.0 4,-0.4 0, 0.0 3,-0.3 0.771 127.4 62.8 -48.1 -35.0 5.9 -6.3 17.6 12 14 A E T 34 S+ 0 0 107 1,-0.2 3,-0.1 2,-0.1 -2,-0.1 0.662 107.3 45.3 -68.2 -15.0 8.9 -7.5 19.6 13 15 A H T X4 S+ 0 0 52 -3,-2.7 3,-1.9 1,-0.1 4,-0.5 0.646 86.3 89.6-100.7 -21.0 11.0 -4.9 17.7 14 16 A W G >X S+ 0 0 4 -4,-0.9 4,-2.6 -3,-0.3 3,-1.0 0.763 72.7 71.0 -50.0 -34.3 8.8 -1.9 17.9 15 17 A H G 34 S+ 0 0 67 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.755 87.7 65.1 -58.5 -26.5 10.2 -0.6 21.1 16 18 A K G <4 S+ 0 0 131 -3,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.879 117.2 25.4 -65.9 -37.0 13.5 0.4 19.4 17 19 A D T <4 S+ 0 0 105 -3,-1.0 -2,-0.2 -4,-0.5 -1,-0.2 0.693 134.6 37.0 -96.7 -23.4 11.7 3.0 17.3 18 20 A F >< - 0 0 58 -4,-2.6 3,-2.5 1,-0.1 -1,-0.2 -0.748 64.7-175.4-133.1 84.1 8.8 3.6 19.7 19 21 A P G > S+ 0 0 101 0, 0.0 3,-1.9 0, 0.0 -1,-0.1 0.752 79.1 73.5 -48.9 -31.4 10.0 3.5 23.3 20 22 A I G > S+ 0 0 54 1,-0.3 3,-2.8 2,-0.2 -5,-0.1 0.635 71.2 88.9 -63.2 -10.5 6.5 3.9 24.6 21 23 A A G < S+ 0 0 6 -3,-2.5 -1,-0.3 1,-0.3 -6,-0.1 0.749 90.4 47.0 -58.1 -22.9 5.9 0.2 23.4 22 24 A K G < S+ 0 0 144 -3,-1.9 -1,-0.3 -4,-0.1 -2,-0.2 0.027 95.2 133.9-106.1 24.8 7.1 -0.7 26.9 23 25 A G < - 0 0 16 -3,-2.8 3,-0.4 1,-0.1 -3,-0.0 0.126 69.0-105.4 -67.5-176.5 4.8 1.9 28.5 24 26 A E S S+ 0 0 121 1,-0.2 226,-0.2 225,-0.1 -1,-0.1 0.613 112.0 35.6 -88.1 -17.8 2.4 1.8 31.5 25 27 A R S S+ 0 0 47 224,-0.1 -1,-0.2 168,-0.1 2,-0.2 -0.324 80.5 153.5-134.6 56.1 -0.9 1.6 29.6 26 28 A Q - 0 0 4 -3,-0.4 220,-0.2 221,-0.3 170,-0.1 -0.505 33.1-101.8 -85.5 153.0 -0.2 -0.4 26.5 27 29 A S S S+ 0 0 0 168,-0.4 2,-0.2 -2,-0.2 -2,-0.0 -0.874 76.6 42.8-126.5 159.2 -2.8 -2.4 24.5 28 30 A P + 0 0 0 0, 0.0 218,-3.2 0, 0.0 2,-0.3 0.597 64.5 174.3 -81.0 179.2 -4.0 -5.0 23.8 29 31 A V - 0 0 1 216,-0.3 77,-1.2 -2,-0.2 2,-0.5 -0.906 36.8 -99.2-140.4 166.7 -4.4 -6.9 27.1 30 32 A D E -a 106 0A 35 216,-0.4 2,-0.8 -2,-0.3 77,-0.2 -0.786 33.9-137.0 -90.3 131.8 -6.0 -10.2 28.2 31 33 A I E -a 107 0A 0 75,-3.3 77,-2.7 -2,-0.5 2,-1.0 -0.818 11.2-158.1 -93.3 110.5 -9.4 -9.7 29.8 32 34 A D >> - 0 0 66 -2,-0.8 4,-1.5 75,-0.2 3,-1.3 -0.800 4.0-159.7 -88.5 103.7 -9.7 -11.8 32.9 33 35 A T T 34 S+ 0 0 47 -2,-1.0 -1,-0.2 1,-0.3 222,-0.0 0.701 87.8 51.3 -59.1 -23.4 -13.4 -12.1 33.3 34 36 A H T 34 S+ 0 0 162 1,-0.1 -1,-0.3 -3,-0.1 -2,-0.0 0.626 112.7 44.0 -91.1 -13.7 -13.2 -13.1 36.9 35 37 A T T <4 S+ 0 0 99 -3,-1.3 -2,-0.2 2,-0.1 -1,-0.1 0.584 88.5 103.0-102.5 -16.4 -11.0 -10.2 37.9 36 38 A A S < S- 0 0 20 -4,-1.5 2,-0.5 216,-0.1 218,-0.2 -0.447 71.4-130.7 -66.8 139.2 -12.9 -7.5 35.9 37 39 A K E -c 254 0B 126 216,-2.4 218,-2.4 -2,-0.1 2,-0.4 -0.832 7.6-128.1-102.6 128.7 -15.0 -5.4 38.2 38 40 A Y E -c 255 0B 94 -2,-0.5 218,-0.2 216,-0.2 220,-0.1 -0.555 23.8-159.4 -69.2 123.4 -18.7 -4.7 37.6 39 41 A D > - 0 0 35 216,-2.5 3,-2.1 -2,-0.4 -1,-0.1 -0.884 11.3-166.7-112.5 102.7 -19.1 -0.9 37.8 40 42 A P T 3 S+ 0 0 100 0, 0.0 -1,-0.1 0, 0.0 216,-0.0 0.708 86.5 64.6 -57.2 -22.8 -22.8 0.1 38.5 41 43 A S T 3 S+ 0 0 99 2,-0.1 2,-0.5 40,-0.0 215,-0.1 0.537 74.0 112.7 -81.3 -5.7 -21.9 3.7 37.6 42 44 A L < - 0 0 28 -3,-2.1 3,-0.1 213,-0.2 38,-0.0 -0.564 62.7-141.4 -72.3 120.8 -21.1 2.8 34.0 43 45 A K - 0 0 132 37,-1.0 39,-0.1 -2,-0.5 3,-0.1 -0.428 28.0 -92.0 -79.2 153.0 -23.7 4.3 31.7 44 46 A P - 0 0 102 0, 0.0 36,-1.6 0, 0.0 2,-0.2 -0.286 48.3-101.1 -62.4 153.6 -25.0 2.4 28.6 45 47 A L E -D 79 0B 16 34,-0.3 2,-0.5 141,-0.2 34,-0.2 -0.498 29.4-149.6 -75.2 146.7 -23.1 3.0 25.4 46 48 A S E -D 78 0B 47 32,-2.8 32,-2.5 -2,-0.2 2,-0.6 -0.939 14.6-176.6-122.2 107.9 -24.7 5.4 22.9 47 49 A V E +D 77 0B 36 -2,-0.5 2,-0.6 30,-0.2 30,-0.2 -0.918 5.5 179.4-108.7 116.0 -24.0 4.7 19.3 48 50 A S E +D 76 0B 41 28,-2.7 28,-2.0 -2,-0.6 3,-0.2 -0.824 24.4 141.4-117.4 89.9 -25.4 7.1 16.7 49 51 A Y > + 0 0 3 -2,-0.6 3,-1.8 26,-0.2 130,-0.2 0.273 34.7 108.7-110.6 8.1 -24.3 5.9 13.2 50 52 A D T 3 S+ 0 0 97 1,-0.3 -1,-0.1 -3,-0.1 25,-0.1 0.794 86.5 40.3 -55.9 -31.4 -27.5 6.7 11.3 51 53 A Q T 3 S+ 0 0 128 23,-0.9 -1,-0.3 -3,-0.2 24,-0.2 0.191 83.6 146.5-104.4 16.1 -25.8 9.6 9.5 52 54 A A < - 0 0 22 -3,-1.8 2,-0.5 22,-0.2 18,-0.1 -0.209 31.7-160.6 -55.6 138.6 -22.5 8.0 8.9 53 55 A T - 0 0 47 16,-0.3 16,-2.6 122,-0.1 2,-0.1 -0.871 3.4-161.5-127.1 98.4 -20.7 8.9 5.6 54 56 A S E +E 68 0B 1 -2,-0.5 121,-0.5 122,-0.3 14,-0.3 -0.443 11.2 177.3 -75.7 153.3 -18.0 6.6 4.4 55 57 A L E - 0 0 77 12,-3.3 118,-2.2 1,-0.4 2,-0.3 0.717 51.2 -11.1-121.9 -52.2 -15.5 7.9 1.9 56 58 A R E -EF 67 172B 92 11,-1.0 11,-2.8 116,-0.3 -1,-0.4 -0.979 44.3-139.9-154.2 161.5 -12.8 5.4 0.9 57 59 A I E +EF 66 171B 0 114,-2.4 114,-2.4 -2,-0.3 2,-0.3 -0.967 29.5 176.1-124.2 140.8 -11.2 2.1 1.7 58 60 A L E -EF 65 170B 31 7,-2.2 7,-2.7 -2,-0.4 2,-0.7 -0.998 33.7-130.8-150.5 154.6 -7.4 1.6 1.6 59 61 A N E +E 64 0B 1 110,-2.6 109,-2.9 -2,-0.3 5,-0.2 -0.912 22.7 177.4-102.0 113.7 -4.6 -0.8 2.1 60 62 A N - 0 0 63 3,-2.0 4,-0.1 -2,-0.7 -1,-0.1 0.262 56.3-100.7-101.8 11.9 -1.9 1.0 4.2 61 63 A G S S+ 0 0 17 2,-0.4 3,-0.1 166,-0.2 106,-0.1 0.266 117.6 61.2 90.6 -12.6 0.4 -2.1 4.4 62 64 A H S S- 0 0 12 1,-0.5 2,-0.3 -58,-0.1 166,-0.1 0.628 122.3 -39.1-113.8 -29.8 -0.7 -2.9 8.0 63 65 A A - 0 0 2 165,-0.1 -3,-2.0 31,-0.1 -1,-0.5 -0.921 69.4 -82.1-174.0-172.4 -4.4 -3.5 7.4 64 66 A F E -E 59 0B 0 -2,-0.3 29,-0.6 29,-0.2 2,-0.4 -0.952 41.7-158.6-114.8 137.8 -7.2 -2.1 5.3 65 67 A H E -EG 58 92B 28 -7,-2.7 -7,-2.2 -2,-0.4 2,-0.6 -0.933 12.4-151.6-120.0 140.4 -9.1 1.0 6.6 66 68 A V E -EG 57 91B 0 25,-2.5 25,-1.2 -2,-0.4 2,-0.3 -0.930 24.3-153.2-110.0 111.9 -12.5 2.4 5.8 67 69 A E E -EG 56 90B 62 -11,-2.8 -12,-3.3 -2,-0.6 -11,-1.0 -0.616 7.8-160.0 -94.5 144.7 -12.5 6.1 6.3 68 70 A F E -E 54 0B 7 21,-2.9 2,-0.7 -2,-0.3 -14,-0.2 -0.774 31.0 -98.9-117.9 162.0 -15.4 8.3 7.2 69 71 A D + 0 0 42 -16,-2.6 -16,-0.3 -2,-0.3 5,-0.3 -0.702 39.8 174.0 -79.0 115.4 -16.2 12.0 6.9 70 72 A D + 0 0 44 -2,-0.7 -1,-0.1 1,-0.1 17,-0.1 -0.047 45.7 107.6-115.3 31.7 -15.5 13.4 10.4 71 73 A S S S+ 0 0 77 56,-0.0 2,-0.3 2,-0.0 -1,-0.1 0.542 89.0 20.7 -83.8 -8.6 -16.0 17.1 9.6 72 74 A Q S S- 0 0 118 -3,-0.2 2,-2.5 3,-0.0 3,-0.5 -0.944 99.0 -85.6-149.9 166.7 -19.3 17.1 11.5 73 75 A D S S+ 0 0 87 -2,-0.3 3,-0.2 1,-0.2 -3,-0.1 -0.413 75.9 131.0 -77.4 67.6 -21.0 15.0 14.2 74 76 A K S S+ 0 0 53 -2,-2.5 -23,-0.9 1,-0.3 2,-0.5 0.903 75.5 21.3 -84.8 -48.2 -22.5 12.5 11.7 75 77 A A S S+ 0 0 7 -3,-0.5 13,-2.9 -6,-0.2 -1,-0.3 -0.950 85.2 166.1-125.4 109.3 -21.4 9.3 13.3 76 78 A V E -DH 48 87B 7 -28,-2.0 -28,-2.7 -2,-0.5 2,-0.4 -0.875 31.2-146.1-130.0 160.6 -20.7 9.5 17.1 77 79 A L E +DH 47 86B 0 9,-2.7 9,-2.0 -2,-0.3 2,-0.3 -0.977 29.3 160.0-122.0 130.7 -20.1 7.5 20.2 78 80 A K E +D 46 0B 73 -32,-2.5 -32,-2.8 -2,-0.4 7,-0.1 -0.857 36.9 32.5-139.8 175.1 -21.3 8.8 23.6 79 81 A G E > S+D 45 0B 9 -2,-0.3 3,-2.1 5,-0.3 -34,-0.3 -0.313 71.0 86.5 75.5-157.7 -22.1 7.4 27.0 80 82 A G T 3 S- 0 0 9 -36,-1.6 -37,-1.0 1,-0.3 -1,-0.1 -0.394 118.7 -26.6 61.0-134.8 -20.4 4.5 28.6 81 83 A P T 3 S+ 0 0 41 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.326 115.2 113.2 -92.0 7.4 -17.2 5.6 30.5 82 84 A L < - 0 0 15 -3,-2.1 2,-0.5 -39,-0.1 -3,-0.2 -0.527 53.8-156.7 -87.6 147.3 -16.9 8.5 28.1 83 85 A D - 0 0 137 -2,-0.2 2,-0.1 53,-0.1 -3,-0.0 -0.980 67.6 -0.9-119.2 112.9 -17.3 12.2 28.8 84 86 A G S S- 0 0 46 -2,-0.5 2,-0.4 39,-0.1 -5,-0.3 -0.390 97.7 -48.2 102.2 179.2 -18.2 14.2 25.7 85 87 A T - 0 0 29 -2,-0.1 38,-2.5 -7,-0.1 2,-0.5 -0.782 42.7-163.2 -99.2 134.4 -18.8 13.3 22.0 86 88 A Y E -HI 77 122B 4 -9,-2.0 -9,-2.7 -2,-0.4 2,-0.4 -0.971 11.5-144.6-118.5 124.8 -16.4 11.1 20.0 87 89 A R E -HI 76 121B 44 34,-2.5 34,-2.1 -2,-0.5 2,-0.2 -0.727 18.1-119.5 -92.7 136.4 -16.6 11.1 16.2 88 90 A L E + I 0 120B 2 -13,-2.9 32,-0.3 -2,-0.4 -13,-0.2 -0.511 36.9 166.7 -70.4 130.6 -16.0 8.0 14.1 89 91 A I E - 0 0 27 30,-2.9 -21,-2.9 1,-0.4 2,-0.3 0.718 59.2 -21.7-113.8 -38.8 -13.0 8.5 11.8 90 92 A Q E -GI 67 119B 29 29,-1.2 29,-2.7 -23,-0.2 -1,-0.4 -0.983 47.8-148.0-164.2 164.6 -12.2 5.0 10.5 91 93 A F E +GI 66 118B 0 -25,-1.2 -25,-2.5 -2,-0.3 2,-0.3 -0.981 20.6 163.6-140.4 151.0 -12.5 1.3 11.2 92 94 A H E -GI 65 117B 16 25,-1.7 25,-3.0 -2,-0.3 2,-0.3 -0.920 22.7-126.2-154.1 174.1 -10.1 -1.6 10.4 93 95 A F E - I 0 116B 1 -29,-0.6 2,-0.4 -2,-0.3 -29,-0.2 -0.785 0.7-147.5-127.9 172.7 -9.5 -5.2 11.4 94 96 A H E + I 0 115B 3 21,-1.2 21,-1.7 -2,-0.3 2,-0.3 -0.986 29.3 169.0-139.1 121.2 -6.8 -7.6 12.6 95 97 A W E - I 0 114B 4 -2,-0.4 146,-1.2 19,-0.2 145,-0.6 -0.820 22.2-124.0-135.8 175.0 -6.8 -11.2 11.6 96 98 A G - 0 0 0 17,-1.2 6,-0.1 5,-0.6 3,-0.1 -0.512 26.7-113.9-113.7-179.1 -4.8 -14.3 11.6 97 99 A S S S+ 0 0 44 -2,-0.2 2,-0.3 142,-0.1 5,-0.1 0.591 106.3 29.4 -86.2 -13.1 -3.5 -17.0 9.3 98 100 A L S > S- 0 0 111 3,-0.2 3,-1.5 15,-0.1 -2,-0.2 -0.943 89.3-109.6-140.9 158.3 -5.8 -19.5 10.9 99 101 A D T 3 S+ 0 0 70 -2,-0.3 48,-0.2 1,-0.3 15,-0.1 0.705 109.9 70.9 -65.2 -18.5 -9.2 -19.3 12.6 100 102 A G T 3 S+ 0 0 58 13,-0.1 2,-0.3 2,-0.1 -1,-0.3 0.451 106.7 26.6 -79.2 0.0 -7.6 -20.0 16.0 101 103 A Q < + 0 0 55 -3,-1.5 -5,-0.6 12,-0.1 -3,-0.2 -0.965 65.7 99.2-153.2 166.4 -5.8 -16.6 16.2 102 104 A G + 0 0 0 1,-0.6 13,-0.3 -2,-0.3 11,-0.2 0.019 55.0 105.1 143.0 -34.2 -6.2 -13.1 14.9 103 105 A S - 0 0 1 9,-1.9 -1,-0.6 11,-0.3 12,-0.1 -0.384 54.1-150.6 -76.3 157.5 -7.7 -10.9 17.7 104 106 A E S S+ 0 0 2 -10,-0.1 2,-0.1 -3,-0.1 -1,-0.1 0.881 83.2 52.4 -92.2 -53.1 -5.6 -8.5 19.7 105 107 A H S S- 0 0 0 -77,-0.1 7,-0.4 140,-0.1 2,-0.3 -0.506 76.2-158.2 -78.7 155.2 -7.5 -8.6 22.9 106 108 A T E -a 30 0A 12 -77,-1.2 -75,-3.3 -2,-0.1 2,-0.5 -0.927 11.4-137.7-131.3 155.5 -8.2 -12.0 24.4 107 109 A V E > S-aB 31 110A 15 3,-1.7 3,-2.3 -2,-0.3 -75,-0.2 -0.965 88.1 -20.7-119.3 113.7 -10.8 -13.1 26.9 108 110 A D T 3 S- 0 0 68 -77,-2.7 -1,-0.2 -2,-0.5 -76,-0.1 0.913 128.6 -54.5 51.8 44.1 -9.6 -15.5 29.6 109 111 A K T 3 S+ 0 0 157 1,-0.2 2,-0.4 -78,-0.1 -1,-0.3 0.396 105.9 138.3 72.3 -1.2 -6.7 -16.2 27.1 110 112 A K B < -B 107 0A 121 -3,-2.3 -3,-1.7 -9,-0.0 2,-0.3 -0.611 41.2-151.3 -78.6 130.7 -9.1 -17.1 24.4 111 113 A K - 0 0 91 -2,-0.4 2,-0.2 -11,-0.2 -5,-0.1 -0.801 5.5-148.8-101.2 143.3 -8.2 -15.8 20.9 112 114 A Y - 0 0 26 -7,-0.4 -9,-1.9 -2,-0.3 34,-0.2 -0.609 28.3-108.0-104.1 168.2 -10.8 -15.0 18.3 113 115 A A S S- 0 0 5 32,-1.2 -17,-1.2 -11,-0.2 2,-0.3 0.774 94.0 -14.1 -67.3 -27.3 -10.4 -15.2 14.5 114 116 A A E -IJ 95 145B 0 31,-1.2 31,-2.4 -19,-0.2 2,-0.4 -0.977 58.0-136.3-165.2 169.1 -10.3 -11.4 14.1 115 117 A E E -IJ 94 144B 0 -21,-1.7 -21,-1.2 -13,-0.3 2,-0.4 -0.993 12.5-147.4-141.9 131.0 -11.0 -8.1 15.9 116 118 A L E -IJ 93 143B 0 27,-3.2 27,-2.4 -2,-0.4 2,-0.5 -0.836 10.9-161.5 -99.0 133.0 -12.7 -5.0 14.5 117 119 A H E -IJ 92 142B 3 -25,-3.0 -25,-1.7 -2,-0.4 2,-0.7 -0.969 6.2-168.0-119.8 117.9 -11.7 -1.6 15.7 118 120 A L E -IJ 91 141B 0 23,-2.3 23,-2.4 -2,-0.5 2,-0.5 -0.927 19.2-152.7-103.7 111.1 -13.9 1.4 15.2 119 121 A V E +IJ 90 140B 8 -29,-2.7 -30,-2.9 -2,-0.7 -29,-1.2 -0.752 17.9 175.3 -94.0 127.0 -11.8 4.5 16.0 120 122 A H E -IJ 88 139B 0 19,-1.5 19,-2.3 -2,-0.5 2,-0.4 -0.938 15.7-146.7-127.0 149.7 -13.4 7.7 17.3 121 123 A W E -IJ 87 138B 6 -34,-2.1 -34,-2.5 -2,-0.3 2,-0.5 -0.927 27.8-103.2-121.5 146.0 -11.8 11.0 18.5 122 124 A N E > -I 86 0B 3 15,-3.1 3,-2.2 -2,-0.4 -36,-0.2 -0.491 23.7-147.8 -66.3 113.3 -12.9 13.4 21.2 123 125 A T G > S+ 0 0 39 -38,-2.5 3,-1.9 -2,-0.5 -1,-0.2 0.721 89.9 78.0 -56.5 -23.0 -14.5 16.5 19.5 124 127 A K G 3 S+ 0 0 132 -39,-0.3 -1,-0.3 1,-0.3 -38,-0.1 0.773 90.5 56.3 -57.9 -25.3 -13.2 18.7 22.3 125 128 A Y G < S- 0 0 50 -3,-2.2 2,-1.5 12,-0.1 -1,-0.3 0.356 101.3-131.3 -92.6 6.4 -9.7 18.6 20.6 126 129 A G S < S+ 0 0 58 -3,-1.9 2,-0.3 -4,-0.1 -3,-0.1 -0.132 75.4 21.0 77.9 -46.2 -10.7 19.8 17.2 127 130 A D S >> S- 0 0 64 -2,-1.5 4,-2.2 -5,-0.2 3,-0.6 -0.981 79.0-105.3-152.9 163.4 -9.0 17.1 15.1 128 131 A F H 3> S+ 0 0 65 -2,-0.3 4,-2.1 1,-0.2 -1,-0.1 0.899 114.9 59.2 -54.7 -46.6 -7.6 13.6 15.2 129 132 A G H 34 S+ 0 0 36 1,-0.2 -1,-0.2 2,-0.2 4,-0.2 0.824 110.8 40.5 -54.6 -37.4 -4.0 14.8 15.2 130 133 A K H X4 S+ 0 0 109 -3,-0.6 3,-1.4 -5,-0.2 -1,-0.2 0.876 110.4 60.0 -78.6 -39.4 -4.5 16.8 18.4 131 134 A A H >< S+ 0 0 0 -4,-2.2 3,-2.0 1,-0.3 6,-0.3 0.851 94.8 61.0 -56.5 -41.2 -6.7 14.1 20.0 132 135 A V T 3< S+ 0 0 21 -4,-2.1 -1,-0.3 1,-0.3 -2,-0.1 0.682 97.8 60.9 -64.3 -15.0 -4.0 11.4 19.9 133 136 A Q T < S+ 0 0 138 -3,-1.4 -1,-0.3 -4,-0.2 -2,-0.2 0.367 94.5 80.4 -92.4 6.3 -1.8 13.6 22.1 134 137 A Q S X S- 0 0 69 -3,-2.0 3,-1.7 69,-0.1 4,-0.3 -0.879 79.7-129.6-116.5 146.3 -4.3 13.6 25.0 135 138 A P T 3 S+ 0 0 79 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 0.765 114.6 32.6 -61.9 -25.9 -5.0 10.9 27.6 136 139 A D T 3 S+ 0 0 48 1,-0.1 -53,-0.1 -5,-0.1 68,-0.1 -0.083 89.1 114.0-119.7 31.0 -8.7 10.9 26.8 137 140 A G S < S+ 0 0 0 -3,-1.7 -15,-3.1 -6,-0.3 2,-0.3 0.862 70.9 35.9 -72.6 -39.6 -8.3 11.7 23.1 138 141 A L E -Jk 121 204B 0 65,-3.0 67,-2.0 -4,-0.3 2,-0.4 -0.845 53.1-162.3-121.3 156.6 -9.6 8.5 21.5 139 142 A A E -Jk 120 205B 0 -19,-2.3 -19,-1.5 -2,-0.3 2,-0.6 -0.959 13.5-166.9-132.2 111.4 -12.3 5.9 22.1 140 143 A V E -Jk 119 206B 2 65,-0.9 67,-2.4 -2,-0.4 2,-0.6 -0.906 9.9-151.1-108.3 127.1 -11.9 2.6 20.3 141 144 A L E -Jk 118 207B 0 -23,-2.4 -23,-2.3 -2,-0.6 2,-0.5 -0.839 16.7-158.3 -93.3 118.4 -14.8 0.2 20.1 142 145 A G E -Jk 117 208B 0 65,-3.1 67,-2.6 -2,-0.6 2,-0.4 -0.870 10.8-176.3-104.7 131.2 -13.5 -3.4 19.8 143 146 A I E -J 116 0B 0 -27,-2.4 -27,-3.2 -2,-0.5 2,-0.2 -0.988 17.6-137.4-129.3 126.9 -15.6 -6.2 18.4 144 147 A F E -J 115 0B 0 -2,-0.4 69,-2.6 65,-0.4 2,-0.4 -0.528 12.2-150.9 -81.5 146.9 -14.5 -9.9 18.2 145 148 A L E -Jl 114 213B 0 -31,-2.4 -31,-1.2 67,-0.2 -32,-1.2 -0.973 12.1-175.0-119.6 130.4 -15.2 -12.0 15.2 146 149 A K E - l 0 214B 100 67,-2.2 69,-2.3 -2,-0.4 2,-0.5 -0.890 31.2-107.7-120.0 154.4 -15.7 -15.8 15.4 147 150 A V E S+ l 0 215B 50 -2,-0.3 69,-0.2 67,-0.2 2,-0.2 -0.703 75.1 85.6 -87.1 128.7 -16.1 -18.1 12.4 148 151 A G S S+ 0 0 46 67,-2.9 69,-0.4 -2,-0.5 2,-0.1 -0.566 77.9 20.1-175.0-114.5 -19.6 -19.5 11.8 149 152 A S S S- 0 0 90 -2,-0.2 -1,-0.3 67,-0.1 -3,-0.1 -0.450 84.6 -99.0 -78.3 152.4 -22.5 -17.9 9.9 150 153 A A - 0 0 57 65,-0.3 65,-0.2 -2,-0.1 64,-0.1 -0.354 26.1-131.1 -70.2 149.8 -21.9 -15.2 7.4 151 154 A K >> - 0 0 50 1,-0.2 3,-2.0 65,-0.1 4,-0.8 -0.898 12.5-157.9-104.6 106.0 -22.4 -11.6 8.3 152 155 A P G >4 S+ 0 0 110 0, 0.0 3,-1.1 0, 0.0 4,-0.4 0.893 89.5 56.9 -48.3 -48.0 -24.6 -10.0 5.6 153 156 A G G 34 S+ 0 0 27 27,-0.4 4,-0.2 1,-0.2 27,-0.2 0.575 102.1 56.3 -64.5 -10.6 -23.4 -6.4 6.5 154 157 A L G X> S+ 0 0 2 -3,-2.0 4,-1.8 1,-0.1 3,-1.1 0.680 83.8 83.8 -93.9 -20.0 -19.7 -7.3 6.0 155 158 A Q H S+ 0 0 138 -4,-0.4 4,-0.6 1,-0.2 -1,-0.3 0.868 109.2 47.5 -57.7 -33.7 -19.8 -5.1 0.8 157 160 A V H X> S+ 0 0 0 -3,-1.1 3,-0.8 -4,-0.2 4,-0.6 0.929 110.8 48.8 -73.1 -46.1 -16.4 -4.8 2.4 158 161 A V H >< S+ 0 0 0 -4,-1.8 3,-0.9 1,-0.2 4,-0.4 0.870 105.2 59.2 -63.9 -35.3 -15.1 -8.3 1.4 159 162 A D H 3< S+ 0 0 90 -4,-2.5 3,-0.3 1,-0.2 -1,-0.2 0.718 105.3 48.2 -68.0 -20.9 -16.2 -7.8 -2.3 160 163 A V H X< S+ 0 0 39 -3,-0.8 3,-1.6 -4,-0.6 4,-0.4 0.530 83.5 91.7 -96.0 -6.9 -14.0 -4.7 -2.8 161 164 A L G X< S+ 0 0 4 -3,-0.9 3,-1.3 -4,-0.6 -1,-0.2 0.805 76.2 66.1 -57.6 -30.9 -10.8 -6.1 -1.3 162 165 A D G > S+ 0 0 116 -4,-0.4 3,-0.7 -3,-0.3 -1,-0.3 0.794 97.3 55.5 -62.0 -27.1 -9.7 -7.3 -4.7 163 166 A S G < S+ 0 0 63 -3,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.580 113.9 38.3 -83.2 -9.7 -9.4 -3.7 -5.8 164 167 A I G < S+ 0 0 0 -3,-1.3 -1,-0.2 -4,-0.4 -2,-0.2 -0.196 73.1 136.1-131.4 41.6 -7.0 -2.8 -2.9 165 168 A K < + 0 0 91 -3,-0.7 62,-2.8 61,-0.1 2,-0.2 0.851 61.7 52.3 -58.5 -40.4 -4.9 -6.0 -2.8 166 169 A T S > S- 0 0 15 60,-0.2 3,-1.9 1,-0.1 -107,-0.3 -0.674 97.7 -83.5-106.6 158.1 -1.5 -4.2 -2.4 167 170 A K B 3 S+o 230 0C 103 62,-2.3 64,-0.5 1,-0.2 -107,-0.2 -0.243 112.8 24.3 -54.9 131.8 -0.1 -1.6 -0.1 168 171 A G T 3 S+ 0 0 63 -109,-2.9 -1,-0.2 1,-0.3 2,-0.1 0.052 89.7 125.5 100.8 -25.5 -0.9 2.0 -1.2 169 172 A K < + 0 0 78 -3,-1.9 -110,-2.6 -5,-0.1 -1,-0.3 -0.420 32.8 174.5 -71.1 142.6 -4.0 1.1 -3.2 170 173 A S E -F 58 0B 58 -112,-0.2 2,-0.3 -7,-0.1 -112,-0.2 -0.954 8.9-169.8-143.5 159.7 -7.3 2.9 -2.3 171 174 A A E -F 57 0B 27 -114,-2.4 -114,-2.4 -2,-0.3 2,-0.1 -0.996 35.6 -90.3-152.6 152.1 -10.8 3.0 -3.7 172 175 A D E +F 56 0B 146 -2,-0.3 -116,-0.3 -116,-0.2 2,-0.2 -0.385 41.0 178.0 -61.8 136.4 -14.1 4.9 -3.4 173 176 A F + 0 0 16 -118,-2.2 3,-0.3 -106,-0.1 2,-0.2 -0.632 12.6 165.3-145.0 80.9 -16.2 3.3 -0.7 174 177 A T + 0 0 87 1,-0.2 -119,-0.2 -2,-0.2 -121,-0.1 -0.607 50.9 22.1-102.3 160.6 -19.4 5.3 -0.2 175 178 A N S S+ 0 0 135 -121,-0.5 2,-0.5 1,-0.2 -1,-0.2 0.806 72.8 153.5 59.4 35.4 -22.7 4.6 1.5 176 179 A F - 0 0 9 -3,-0.3 -122,-0.3 -20,-0.0 -1,-0.2 -0.847 35.4-146.7 -95.0 128.4 -21.4 1.9 3.8 177 180 A D > - 0 0 65 -2,-0.5 3,-1.6 1,-0.1 -127,-0.1 -0.833 7.8-163.8 -98.1 109.2 -23.5 1.5 7.0 178 181 A P G > S+ 0 0 0 0, 0.0 3,-1.9 0, 0.0 4,-0.2 0.640 79.3 82.2 -66.3 -12.2 -21.3 0.5 10.0 179 182 A R G > S+ 0 0 126 1,-0.3 3,-1.0 -130,-0.2 -26,-0.1 0.712 78.9 69.1 -65.1 -18.3 -24.4 -0.5 12.0 180 183 A G G < S+ 0 0 31 -3,-1.6 -27,-0.4 1,-0.2 -1,-0.3 0.491 93.4 57.5 -78.6 -1.2 -24.4 -3.8 10.1 181 184 A L G < S+ 0 0 1 -3,-1.9 -1,-0.2 -28,-0.1 -2,-0.2 0.398 84.6 103.2-107.0 0.5 -21.2 -4.8 12.0 182 185 A L < - 0 0 30 -3,-1.0 4,-0.1 -4,-0.2 -39,-0.0 -0.621 66.8-127.9 -90.1 142.2 -22.6 -4.5 15.5 183 186 A P - 0 0 11 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.227 30.6-104.1 -76.2 174.7 -23.6 -7.4 17.7 184 187 A E S S+ 0 0 180 2,-0.0 2,-0.3 -2,-0.0 29,-0.0 0.929 102.6 53.3 -66.1 -47.4 -27.1 -7.5 19.3 185 188 A S - 0 0 29 1,-0.1 26,-0.2 2,-0.1 24,-0.0 -0.652 60.8-160.0 -93.7 147.8 -25.8 -6.6 22.8 186 189 A L + 0 0 60 -2,-0.3 -141,-0.2 23,-0.1 -1,-0.1 0.127 43.7 137.4-109.4 17.6 -23.7 -3.6 23.8 187 190 A D + 0 0 64 -143,-0.1 23,-2.1 22,-0.1 24,-0.5 -0.392 34.8 174.9 -62.1 144.3 -22.5 -5.0 27.1 188 191 A Y E -M 209 0B 1 21,-0.3 68,-2.7 22,-0.1 2,-0.3 -0.935 38.1-130.9-151.6 170.8 -18.8 -4.2 27.4 189 192 A W E -MN 208 255B 14 19,-2.1 19,-2.6 -2,-0.3 2,-0.4 -0.899 30.1-167.1-117.8 146.6 -15.5 -4.1 29.3 190 193 A T E +MN 207 254B 7 64,-2.6 64,-2.5 -2,-0.3 17,-0.2 -0.999 16.3 153.9-144.1 145.3 -13.4 -0.9 29.4 191 194 A Y E -M 206 0B 6 15,-1.2 15,-2.4 -2,-0.4 2,-0.4 -0.975 46.1 -94.9-159.9 158.3 -9.9 0.1 30.4 192 195 A P E +M 205 0B 54 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.680 62.2 133.9 -82.2 130.4 -7.4 2.9 29.6 193 196 A G E -M 204 0B 0 11,-3.5 11,-1.5 -2,-0.4 2,-0.2 -0.536 41.1 -96.9-146.7-146.9 -4.9 1.9 26.9 194 197 A S - 0 0 0 8,-0.2 8,-0.2 9,-0.2 2,-0.1 -0.795 43.0 -74.8-139.6 179.9 -3.1 2.7 23.7 195 198 A L - 0 0 28 6,-1.8 -168,-0.4 -2,-0.2 9,-0.0 -0.515 38.2-139.1 -73.2 150.1 -3.1 2.4 20.0 196 199 A T S S+ 0 0 5 -2,-0.1 -1,-0.1 -170,-0.1 -170,-0.0 0.429 83.2 53.6 -96.8 6.3 -2.0 -1.1 19.0 197 200 A T S > S- 0 0 38 4,-0.1 3,-2.5 1,-0.0 4,-0.2 -0.928 102.8 -44.9-129.3 154.0 0.2 0.0 16.1 198 201 A P T 3 S+ 0 0 11 0, 0.0 -2,-0.1 0, 0.0 -1,-0.0 -0.242 124.0 41.8 -52.5 147.4 3.0 2.6 16.1 199 202 A P T 3 S- 0 0 65 0, 0.0 -179,-0.2 0, 0.0 -178,-0.0 -0.975 84.5-164.2 -70.4 4.2 3.1 5.4 17.3 200 203 A L < - 0 0 0 -3,-2.5 -173,-0.1 1,-0.2 -182,-0.0 0.770 17.0-175.2 54.7 31.6 1.4 3.3 20.1 201 204 A L - 0 0 52 -4,-0.2 -6,-1.8 -7,-0.1 2,-1.6 -0.260 30.4-127.2 -61.9 142.0 0.3 6.5 21.9 202 205 A E S S+ 0 0 48 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.517 76.7 109.6 -91.7 70.9 -1.5 6.0 25.2 203 206 A C + 0 0 1 -2,-1.6 -65,-3.0 -67,-0.1 2,-0.4 0.151 48.1 110.0-128.2 13.5 -4.5 8.1 24.3 204 207 A V E -kM 138 193B 0 -11,-1.5 -11,-3.5 -3,-0.3 2,-0.7 -0.813 48.5-160.6-108.4 136.6 -7.2 5.4 24.1 205 208 A T E -kM 139 192B 27 -67,-2.0 -65,-0.9 -2,-0.4 2,-0.3 -0.942 30.6-144.5-102.2 100.7 -10.2 4.5 26.2 206 209 A W E -kM 140 191B 3 -15,-2.4 -15,-1.2 -2,-0.7 2,-0.5 -0.539 20.5-175.7 -78.4 136.2 -10.9 1.0 25.2 207 210 A I E -kM 141 190B 0 -67,-2.4 -65,-3.1 -2,-0.3 2,-0.6 -0.930 9.4-174.0-128.2 102.4 -14.5 -0.3 24.9 208 211 A V E -kM 142 189B 0 -19,-2.6 -19,-2.1 -2,-0.5 -65,-0.2 -0.890 19.6-133.0-105.7 119.0 -14.5 -4.0 24.1 209 212 A L E - M 0 188B 0 -67,-2.6 -65,-0.4 -2,-0.6 -21,-0.3 -0.450 2.2-145.9 -72.6 138.9 -17.9 -5.7 23.5 210 213 A K S S+ 0 0 95 -23,-2.1 -1,-0.1 -2,-0.2 -22,-0.1 0.856 82.2 70.6 -70.1 -38.0 -18.6 -9.0 25.2 211 214 A E S S- 0 0 62 -24,-0.5 -67,-0.1 -26,-0.2 -2,-0.1 -0.717 73.9-150.9 -88.9 119.0 -20.7 -10.4 22.3 212 215 A P - 0 0 24 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.392 12.0-126.8 -82.6 164.6 -18.7 -11.3 19.2 213 216 A I E -l 145 0B 4 -69,-2.6 -67,-2.2 -30,-0.1 2,-0.4 -0.812 22.6-124.0-105.8 152.7 -20.2 -11.2 15.7 214 217 A S E +l 146 0B 35 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.809 27.6 179.1-100.8 140.3 -20.1 -14.3 13.4 215 218 A V E -l 147 0B 0 -69,-2.3 -67,-2.9 -2,-0.4 -65,-0.3 -0.918 30.7-105.3-130.8 156.2 -18.5 -14.2 9.9 216 219 A S > - 0 0 9 -2,-0.3 4,-2.1 -69,-0.2 5,-0.3 -0.418 24.3-115.1 -84.2 161.1 -18.2 -17.1 7.5 217 220 A S H > S+ 0 0 49 -69,-0.4 4,-1.9 1,-0.2 5,-0.1 0.893 118.3 55.0 -58.0 -38.5 -15.0 -19.0 6.7 218 221 A E H > S+ 0 0 136 1,-0.2 4,-1.1 2,-0.2 -1,-0.2 0.852 105.9 51.1 -64.6 -36.7 -15.3 -17.6 3.1 219 222 A Q H > S+ 0 0 3 -3,-0.3 4,-0.9 2,-0.2 3,-0.4 0.940 112.7 43.5 -68.2 -46.9 -15.5 -14.0 4.3 220 223 A V H X S+ 0 0 5 -4,-2.1 4,-1.4 1,-0.2 3,-0.4 0.835 106.2 64.1 -68.1 -30.0 -12.4 -14.2 6.5 221 224 A L H < S+ 0 0 71 -4,-1.9 -1,-0.2 -5,-0.3 -2,-0.2 0.871 97.8 54.7 -60.9 -37.1 -10.6 -16.1 3.8 222 225 A K H >< S+ 0 0 51 -4,-1.1 3,-1.4 -3,-0.4 -1,-0.2 0.832 101.1 59.2 -66.5 -31.5 -10.8 -13.0 1.5 223 226 A F H >< S+ 0 0 2 -4,-0.9 3,-1.5 -3,-0.4 -1,-0.2 0.911 101.2 56.8 -59.6 -43.0 -9.1 -11.0 4.2 224 227 A R T 3< S+ 0 0 29 -4,-1.4 -1,-0.3 1,-0.3 -2,-0.2 0.458 92.2 69.8 -70.2 -2.6 -6.2 -13.3 4.0 225 228 A K T < S+ 0 0 127 -3,-1.4 -1,-0.3 -4,-0.2 -2,-0.2 0.495 77.4 103.1 -94.1 -3.6 -5.7 -12.7 0.3 226 229 A L < - 0 0 2 -3,-1.5 12,-3.4 12,-0.3 2,-0.4 -0.309 67.1-128.8 -74.3 162.3 -4.5 -9.1 0.8 227 230 A N B -P 237 0D 6 -62,-2.8 10,-0.2 10,-0.3 -166,-0.2 -0.916 14.8-157.4-118.8 142.7 -0.8 -8.3 0.6 228 231 A F S S+ 0 0 40 8,-2.6 -1,-0.1 -2,-0.4 9,-0.1 0.873 81.4 75.3 -76.3 -41.7 1.6 -6.4 3.0 229 232 A N S S- 0 0 9 7,-0.6 -62,-2.3 5,-0.2 2,-0.2 -0.114 87.3-110.5 -67.8 164.8 3.8 -5.6 0.0 230 233 A G B > -o 167 0C 9 -64,-0.2 3,-1.0 1,-0.2 -62,-0.1 -0.538 49.1 -75.0 -93.0 163.4 3.2 -3.0 -2.7 231 234 A E T 3 S+ 0 0 142 -64,-0.5 -1,-0.2 1,-0.2 4,-0.0 -0.269 119.1 31.2 -57.5 141.0 2.5 -3.9 -6.3 232 235 A G T 3 S+ 0 0 81 1,-0.3 -1,-0.2 -3,-0.1 -2,-0.0 0.650 102.3 100.0 84.9 15.3 5.5 -5.1 -8.2 233 236 A E S < S- 0 0 108 -3,-1.0 -1,-0.3 1,-0.0 3,-0.1 -0.846 88.0 -69.6-128.9 165.3 7.2 -6.7 -5.2 234 237 A P - 0 0 113 0, 0.0 2,-0.3 0, 0.0 -5,-0.2 -0.325 62.5-108.3 -55.1 129.5 7.5 -10.2 -3.8 235 238 A E + 0 0 117 -7,-0.1 2,-0.5 -8,-0.1 -8,-0.0 -0.462 40.1 176.3 -69.8 124.4 4.1 -11.3 -2.5 236 239 A E - 0 0 123 -2,-0.3 -8,-2.6 -3,-0.1 -7,-0.6 -0.984 30.0-126.7-127.3 113.6 3.7 -11.5 1.3 237 240 A L B -P 227 0D 88 -2,-0.5 2,-1.4 -10,-0.2 -10,-0.3 -0.372 18.7-120.8 -65.0 137.7 0.2 -12.3 2.4 238 241 A M + 0 0 0 -12,-3.4 -12,-0.3 -15,-0.2 2,-0.3 -0.656 62.6 131.8 -81.5 92.6 -1.4 -9.9 4.9 239 242 A V + 0 0 30 -2,-1.4 -143,-0.2 1,-0.2 -142,-0.1 -0.962 53.0 25.5-140.6 156.3 -2.1 -12.3 7.8 240 243 A D + 0 0 42 -145,-0.6 2,-0.6 -2,-0.3 -144,-0.2 0.914 63.2 158.5 55.1 48.5 -1.4 -12.2 11.6 241 244 A N + 0 0 0 -146,-1.2 2,-0.3 -3,-0.1 -1,-0.2 -0.325 36.2 114.4 -95.5 49.9 -1.4 -8.4 11.7 242 245 A W - 0 0 43 -2,-0.6 -139,-0.1 -148,-0.1 -138,-0.1 -0.922 63.1-130.5-123.1 147.9 -2.1 -8.4 15.4 243 246 A R - 0 0 5 -2,-0.3 3,-0.1 1,-0.1 -2,-0.1 -0.791 31.5-114.4 -96.2 137.1 -0.1 -7.4 18.5 244 247 A P - 0 0 55 0, 0.0 -140,-0.1 0, 0.0 -1,-0.1 -0.272 45.4 -78.9 -67.0 156.9 0.3 -9.8 21.4 245 248 A A - 0 0 49 -141,-0.1 -216,-0.3 1,-0.1 -218,-0.1 -0.234 49.4-146.5 -58.2 141.9 -1.3 -9.0 24.8 246 249 A Q - 0 0 48 -218,-3.2 -216,-0.4 -220,-0.2 -1,-0.1 -0.651 30.7 -74.9-108.8 165.1 0.7 -6.6 26.9 247 250 A P - 0 0 74 0, 0.0 -221,-0.3 0, 0.0 -1,-0.1 -0.340 31.0-147.6 -60.8 133.6 1.2 -6.3 30.7 248 251 A L + 0 0 57 1,-0.2 3,-0.0 -223,-0.1 -219,-0.0 0.852 35.3 170.6 -70.9 -33.6 -1.9 -4.9 32.5 249 252 A K - 0 0 93 1,-0.2 2,-1.5 -224,-0.1 -1,-0.2 -0.272 63.9 -7.7 59.7-143.0 0.3 -3.3 35.1 250 253 A N S S+ 0 0 157 -226,-0.2 2,-0.3 2,-0.0 -1,-0.2 -0.344 108.3 109.8 -81.2 57.0 -1.5 -0.9 37.4 251 254 A R - 0 0 31 -2,-1.5 2,-0.4 -3,-0.0 -3,-0.0 -0.956 52.6-148.9-132.2 151.0 -4.8 -0.9 35.6 252 255 A Q - 0 0 102 -2,-0.3 2,-0.5 -216,-0.0 -216,-0.1 -0.961 12.7-139.5-120.6 135.9 -8.3 -2.3 36.3 253 256 A I - 0 0 9 -2,-0.4 -216,-2.4 -218,-0.1 2,-0.3 -0.817 21.0-157.4 -93.0 129.1 -10.7 -3.6 33.7 254 257 A K E -cN 37 190B 83 -64,-2.5 -64,-2.6 -2,-0.5 2,-0.4 -0.804 0.6-149.4-106.9 149.9 -14.3 -2.6 34.5 255 258 A A E -cN 38 189B 5 -218,-2.4 -216,-2.5 -2,-0.3 -66,-0.2 -0.920 14.6-149.6-119.7 145.8 -17.4 -4.3 33.2 256 259 A S S S+ 0 0 27 -68,-2.7 2,-0.3 -2,-0.4 -67,-0.1 0.376 84.3 49.5 -90.4 3.1 -20.8 -2.8 32.4 257 260 A F 0 0 35 -69,-0.3 -218,-0.1 -70,-0.0 -2,-0.1 -0.947 360.0 360.0-140.8 160.1 -22.5 -6.1 33.3 258 261 A K 0 0 199 -2,-0.3 -2,-0.0 -220,-0.1 -221,-0.0 -0.412 360.0 360.0-129.1 360.0 -22.5 -8.7 36.0