==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=11-DEC-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSCRIPTION/INHIBITOR 21-NOV-11 3UR4 . COMPND 2 MOLECULE: WD REPEAT-CONTAINING PROTEIN 5; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.DONG,L.DOMBROVSKI,G.SENISTERRA,A.WERNIMONT,G.A.WASNEY,A.AL . 604 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 23621.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 390 64.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 266 44.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 24 4.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 10 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 8 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 57 9.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 21 3.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 16 2.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 1 12 27 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 31 A V 0 0 159 0, 0.0 256,-0.0 0, 0.0 303,-0.0 0.000 360.0 360.0 360.0 -53.2 32.2 4.4 41.2 2 32 A K - 0 0 90 255,-0.0 263,-0.1 239,-0.0 2,-0.0 -0.996 360.0-132.6-135.6 132.7 32.0 7.1 38.4 3 33 A P - 0 0 8 0, 0.0 252,-0.0 0, 0.0 299,-0.0 -0.320 6.2-149.6 -75.3 164.0 34.8 8.6 36.3 4 34 A N + 0 0 73 300,-0.3 297,-0.1 261,-0.1 261,-0.0 -0.269 21.2 179.7-131.1 47.9 35.1 12.3 35.8 5 35 A Y - 0 0 10 297,-0.1 2,-0.3 295,-0.1 297,-0.2 -0.236 5.7-177.1 -51.9 128.2 36.7 12.7 32.3 6 36 A A E -A 301 0A 53 295,-1.7 295,-2.2 261,-0.1 2,-0.2 -0.964 33.7 -93.4-130.9 149.3 37.2 16.3 31.4 7 37 A L E +A 300 0A 79 -2,-0.3 293,-0.2 293,-0.2 3,-0.1 -0.429 43.6 164.3 -67.5 126.8 38.5 17.9 28.1 8 38 A K E + 0 0 116 291,-3.2 2,-0.3 1,-0.4 292,-0.2 0.770 62.9 8.4-107.9 -44.1 42.3 18.6 28.2 9 39 A F E -A 299 0A 78 290,-1.6 290,-2.6 2,-0.0 2,-0.5 -0.996 48.3-153.8-142.5 147.1 43.1 19.1 24.5 10 40 A T E -A 298 0A 67 -2,-0.3 2,-0.7 288,-0.2 288,-0.2 -0.993 22.0-152.2-116.2 121.9 41.5 19.4 21.1 11 41 A L E -A 297 0A 8 286,-3.8 286,-1.8 -2,-0.5 2,-0.3 -0.854 15.1-175.5-104.3 108.8 43.9 18.3 18.3 12 42 A A + 0 0 75 -2,-0.7 284,-0.1 284,-0.2 3,-0.1 -0.771 41.3 92.4-103.4 146.5 43.3 20.0 14.9 13 43 A G + 0 0 36 1,-0.5 -1,-0.1 282,-0.4 2,-0.1 0.072 50.6 103.9 163.3 -38.5 45.1 19.2 11.7 14 44 A H - 0 0 11 281,-0.5 -1,-0.5 -3,-0.3 4,-0.1 -0.443 51.6-156.4 -69.0 145.0 43.3 16.6 9.7 15 45 A T S S+ 0 0 99 2,-0.1 2,-0.3 -2,-0.1 -1,-0.1 0.432 74.5 30.5-107.1 -3.9 41.4 18.1 6.7 16 46 A K S S- 0 0 120 1,-0.1 20,-0.2 279,-0.1 -2,-0.0 -0.818 110.6 -44.3-135.6-178.3 38.8 15.3 6.4 17 47 A A - 0 0 13 -2,-0.3 18,-2.6 17,-0.1 19,-0.4 -0.123 55.4-127.1 -46.2 137.4 37.0 12.8 8.8 18 48 A V E -D 34 0B 0 272,-2.2 16,-0.3 16,-0.2 257,-0.2 -0.744 25.1-175.4 -86.8 140.6 39.3 11.1 11.3 19 49 A S E + 0 0 24 14,-2.7 2,-0.3 -2,-0.4 15,-0.2 0.748 57.0 6.8-106.8 -33.2 39.0 7.4 11.2 20 50 A S E -D 33 0B 3 13,-1.1 13,-2.1 40,-0.1 2,-0.4 -0.984 47.3-165.5-159.3 137.4 41.1 5.9 14.1 21 51 A V E +D 32 0B 0 -2,-0.3 2,-0.3 11,-0.2 11,-0.2 -0.988 15.1 177.5-125.0 139.7 43.2 6.9 17.1 22 52 A K E -D 31 0B 22 9,-2.4 9,-2.9 -2,-0.4 2,-0.4 -0.990 23.4-135.4-143.0 133.1 45.6 4.6 18.9 23 53 A F E -D 30 0B 21 -2,-0.3 7,-0.2 7,-0.2 42,-0.2 -0.694 33.3-111.6 -82.4 136.4 48.0 5.1 21.8 24 54 A S > - 0 0 0 5,-2.4 3,-2.3 -2,-0.4 43,-0.1 -0.353 28.6-114.4 -60.2 147.0 51.4 3.7 21.4 25 55 A P T 3 S+ 0 0 62 0, 0.0 -1,-0.1 0, 0.0 42,-0.1 0.813 117.7 58.1 -57.6 -29.9 52.0 0.7 23.8 26 56 A N T 3 S- 0 0 85 1,-0.1 -2,-0.1 256,-0.0 41,-0.0 0.405 110.4-124.3 -79.2 1.9 54.7 2.8 25.6 27 57 A G S < S+ 0 0 0 -3,-2.3 -1,-0.1 2,-0.1 17,-0.1 0.367 83.1 107.5 77.2 -5.4 52.1 5.5 26.4 28 58 A E S S+ 0 0 90 16,-0.1 16,-2.3 15,-0.1 17,-0.4 0.831 73.1 34.2 -77.5 -34.7 54.2 8.2 24.7 29 59 A W E - E 0 43B 49 14,-0.2 -5,-2.4 15,-0.2 2,-0.4 -0.817 54.8-146.8-126.9 155.4 52.2 8.9 21.5 30 60 A L E -DE 23 42B 0 12,-2.7 12,-2.7 -2,-0.3 2,-0.4 -0.992 18.8-158.8-114.3 133.3 48.9 9.0 19.8 31 61 A A E -DE 22 41B 0 -9,-2.9 -9,-2.4 -2,-0.4 2,-0.3 -0.926 9.7-170.8-106.0 137.6 48.6 8.0 16.2 32 62 A S E -DE 21 40B 0 8,-2.6 8,-2.1 -2,-0.4 2,-0.3 -0.956 6.4-163.5-125.7 147.0 45.6 9.2 14.1 33 63 A S E -DE 20 39B 0 -13,-2.1 -14,-2.7 -2,-0.3 -13,-1.1 -0.909 13.5-176.9-124.9 159.7 44.5 8.2 10.6 34 64 A S E > -D 18 0B 0 4,-1.0 26,-2.1 -2,-0.3 3,-1.5 -0.977 46.0-107.8-153.1 158.7 42.0 10.1 8.3 35 65 A A T 3 S+ 0 0 41 -18,-2.6 24,-0.1 -2,-0.3 -17,-0.1 0.655 109.0 79.8 -58.8 -16.8 40.1 10.2 5.0 36 66 A D T 3 S- 0 0 10 -19,-0.4 -1,-0.3 2,-0.2 3,-0.1 0.351 113.2-113.1 -76.4 7.8 42.7 12.9 4.2 37 67 A K S < S+ 0 0 105 -3,-1.5 18,-0.5 1,-0.2 19,-0.5 0.510 78.8 118.0 76.6 8.5 45.2 10.1 3.4 38 68 A L - 0 0 43 -4,-0.1 -4,-1.0 16,-0.1 2,-0.4 -0.805 54.0-152.4-116.3 148.7 47.4 11.1 6.3 39 69 A I E -EF 33 53B 0 14,-2.3 14,-3.6 -2,-0.3 2,-0.4 -0.951 21.0-165.4-106.5 133.5 48.7 9.6 9.5 40 70 A K E -EF 32 52B 21 -8,-2.1 -8,-2.6 -2,-0.4 2,-0.4 -0.958 8.6-150.7-121.6 144.5 49.5 12.1 12.3 41 71 A I E -EF 31 51B 1 10,-2.5 9,-3.3 -2,-0.4 10,-1.2 -0.944 18.4-180.0-114.7 133.1 51.5 11.6 15.5 42 72 A W E -EF 30 49B 5 -12,-2.7 -12,-2.7 -2,-0.4 2,-0.3 -0.960 36.7 -99.6-133.0 148.5 50.8 13.6 18.6 43 73 A G E > -E 29 0B 7 5,-2.8 4,-1.4 -2,-0.3 -14,-0.2 -0.510 29.4-145.2 -66.1 128.3 52.2 13.8 22.2 44 74 A A T 4 S+ 0 0 2 -16,-2.3 -15,-0.2 -2,-0.3 -1,-0.1 0.774 93.7 34.5 -66.9 -26.3 49.9 11.7 24.4 45 75 A Y T 4 S+ 0 0 114 -17,-0.4 -1,-0.2 3,-0.1 -16,-0.1 0.756 130.6 27.1-105.3 -30.6 50.3 13.9 27.4 46 76 A D T 4 S- 0 0 88 2,-0.1 -2,-0.2 -37,-0.0 3,-0.1 0.401 93.4-130.8-111.0 -3.0 50.7 17.5 26.0 47 77 A G < + 0 0 11 -4,-1.4 2,-0.3 1,-0.2 -3,-0.1 0.584 49.0 161.8 64.7 11.8 48.7 16.9 22.8 48 78 A K - 0 0 119 -6,-0.1 -5,-2.8 1,-0.1 -1,-0.2 -0.467 44.2-116.8 -71.7 125.1 51.6 18.5 20.8 49 79 A F E +F 42 0B 86 -2,-0.3 -7,-0.3 -7,-0.2 -1,-0.1 -0.396 35.6 177.5 -58.9 131.9 51.6 17.7 17.1 50 80 A E E - 0 0 80 -9,-3.3 2,-0.3 1,-0.4 -8,-0.2 0.854 49.1 -34.5-105.7 -55.9 54.7 15.7 16.2 51 81 A K E -F 41 0B 55 -10,-1.2 -10,-2.5 2,-0.0 2,-0.4 -0.986 43.5-118.5-164.3 163.4 54.7 14.8 12.5 52 82 A T E -F 40 0B 55 -2,-0.3 2,-0.5 -12,-0.2 -12,-0.2 -0.946 21.4-155.4-109.4 133.8 52.6 13.8 9.5 53 83 A I E +F 39 0B 1 -14,-3.6 -14,-2.3 -2,-0.4 2,-0.3 -0.955 21.4 179.2-112.0 121.0 53.2 10.5 7.8 54 84 A S + 0 0 77 -2,-0.5 37,-0.1 35,-0.3 -16,-0.1 -0.862 34.6 98.8-126.9 155.2 52.2 10.3 4.1 55 85 A G + 0 0 43 -18,-0.5 -1,-0.1 1,-0.4 -17,-0.1 0.083 48.1 114.3 160.2 -32.1 52.2 7.9 1.2 56 86 A H - 0 0 11 -19,-0.5 -1,-0.4 1,-0.1 4,-0.1 -0.375 54.8-147.3 -63.1 143.8 48.8 6.3 0.9 57 87 A K S S+ 0 0 119 2,-0.1 2,-0.3 -3,-0.1 -1,-0.1 0.608 79.3 24.4 -89.9 -15.1 47.0 7.3 -2.4 58 88 A L S S- 0 0 88 1,-0.2 20,-0.2 -21,-0.1 -3,-0.1 -0.821 103.8 -54.3-139.5 178.5 43.6 7.2 -0.8 59 89 A G - 0 0 11 -2,-0.3 18,-2.9 -24,-0.1 19,-0.4 -0.035 47.3-129.5 -59.3 159.9 41.9 7.6 2.6 60 90 A I E -G 76 0C 4 -26,-2.1 16,-0.3 16,-0.2 -41,-0.2 -0.940 19.6-176.9-118.3 130.7 42.9 5.6 5.7 61 91 A S E + 0 0 38 14,-2.6 2,-0.3 41,-0.5 15,-0.2 0.690 68.2 13.8 -94.3 -25.1 40.4 3.7 7.9 62 92 A D E -G 75 0C 9 13,-1.2 13,-2.5 40,-0.2 2,-0.3 -0.995 49.4-169.6-156.2 154.0 42.8 2.3 10.6 63 93 A V E -G 74 0C 0 -2,-0.3 2,-0.3 11,-0.2 11,-0.2 -0.982 11.7-173.3-145.4 146.5 46.2 2.5 12.1 64 94 A A E -G 73 0C 2 9,-2.2 9,-2.5 -2,-0.3 2,-0.3 -0.996 16.5-127.9-147.3 148.5 47.9 0.2 14.7 65 95 A W E -G 72 0C 21 -2,-0.3 42,-0.4 7,-0.2 7,-0.2 -0.673 17.9-122.8 -97.3 145.9 51.2 0.1 16.7 66 96 A S > - 0 0 1 5,-2.4 3,-1.9 -2,-0.3 45,-0.1 -0.461 37.6-106.2 -74.0 159.3 53.9 -2.6 17.0 67 97 A S T 3 S+ 0 0 62 41,-0.4 -1,-0.1 1,-0.3 44,-0.1 0.776 120.5 53.1 -62.2 -29.3 54.5 -3.7 20.6 68 98 A D T 3 S- 0 0 98 -43,-0.1 -1,-0.3 -42,-0.0 -44,-0.0 0.337 109.6-123.1 -87.3 5.5 57.9 -1.8 20.8 69 99 A S S < S+ 0 0 10 -3,-1.9 -2,-0.1 2,-0.1 -45,-0.1 0.597 86.7 105.0 64.1 14.9 56.1 1.4 19.7 70 100 A N S S+ 0 0 85 16,-0.1 16,-2.3 15,-0.1 17,-0.5 0.741 71.3 48.6 -95.2 -26.3 58.5 1.8 16.7 71 101 A L E - H 0 85C 32 14,-0.2 -5,-2.4 15,-0.1 2,-0.3 -0.826 57.7-165.0-119.1 153.8 56.3 0.7 13.9 72 102 A L E -GH 65 84C 0 12,-1.9 12,-3.1 -2,-0.3 2,-0.4 -0.970 5.4-157.4-128.7 148.7 52.8 1.5 12.6 73 103 A V E -GH 64 83C 0 -9,-2.5 -9,-2.2 -2,-0.3 2,-0.3 -0.983 12.0-163.5-121.0 142.7 50.6 -0.2 10.1 74 104 A S E -GH 63 82C 0 8,-1.9 8,-1.4 -2,-0.4 2,-0.5 -0.932 10.8-145.9-124.9 151.0 47.8 1.6 8.2 75 105 A A E -GH 62 81C 0 -13,-2.5 -14,-2.6 -2,-0.3 -13,-1.2 -0.968 27.3-174.5-120.3 123.7 44.8 0.3 6.3 76 106 A S E > -G 60 0C 0 4,-2.1 26,-2.5 -2,-0.5 3,-1.2 -0.800 43.7-122.8-127.5 156.7 43.6 2.2 3.2 77 107 A D T 3 S+ 0 0 42 -18,-2.9 -17,-0.1 -2,-0.3 -18,-0.1 0.602 104.3 80.2 -63.4 -14.9 41.0 2.6 0.5 78 108 A D T 3 S- 0 0 28 -19,-0.4 -1,-0.3 2,-0.2 3,-0.1 0.353 114.6-112.3 -77.4 8.6 44.0 2.3 -1.9 79 109 A K S < S+ 0 0 104 -3,-1.2 18,-0.5 1,-0.3 19,-0.4 0.441 84.3 99.0 77.2 4.5 43.7 -1.5 -1.3 80 110 A T E - I 0 96C 17 16,-0.1 -4,-2.1 22,-0.1 2,-0.4 -0.753 61.1-143.9-115.0 160.7 47.0 -1.6 0.6 81 111 A L E -HI 75 95C 0 14,-1.4 14,-3.4 -2,-0.3 2,-0.4 -0.911 21.2-153.0-107.3 151.3 48.4 -1.6 4.0 82 112 A K E -HI 74 94C 29 -8,-1.4 -8,-1.9 -2,-0.4 2,-0.5 -0.984 6.7-145.1-124.4 139.6 51.6 0.2 4.7 83 113 A I E -HI 73 93C 3 10,-2.6 9,-3.3 -2,-0.4 10,-1.1 -0.907 25.4-165.1 -99.2 128.6 54.2 -0.5 7.4 84 114 A W E -HI 72 91C 3 -12,-3.1 -12,-1.9 -2,-0.5 2,-0.7 -0.905 26.1-137.5-119.7 140.7 55.9 2.7 8.7 85 115 A D E > -H 71 0C 38 5,-2.4 4,-2.5 -2,-0.4 5,-0.5 -0.885 22.6-155.7 -87.0 114.8 59.0 3.5 10.8 86 116 A V T 4 S+ 0 0 10 -16,-2.3 -1,-0.2 -2,-0.7 -15,-0.1 0.896 87.5 51.4 -62.8 -43.2 57.5 6.1 13.1 87 117 A S T 4 S+ 0 0 90 -17,-0.5 -1,-0.2 1,-0.2 -16,-0.1 0.880 122.5 30.2 -63.2 -40.7 60.9 7.8 13.8 88 118 A S T 4 S- 0 0 63 2,-0.1 -1,-0.2 -3,-0.0 -2,-0.2 0.715 95.2-135.8 -89.4 -23.4 61.8 8.2 10.1 89 119 A G < + 0 0 21 -4,-2.5 -35,-0.3 1,-0.3 2,-0.2 0.487 57.0 142.3 76.7 5.4 58.3 8.5 8.7 90 120 A K - 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