==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER RNA-BINDING PROTEIN 29-JAN-04 1UW4 . COMPND 2 MOLECULE: REGULATOR OF NONSENSE TRANSCRIPTS 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR J.KADLEC,E.IZAURRALDE,S.CUSACK . 675 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 33622.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 479 71.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 50 7.4 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 4 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 25 3.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 73 10.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 311 46.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 10 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 2 2 1 5 2 4 2 0 2 0 0 2 0 2 2 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 2 2 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 50 A L 0 0 87 0, 0.0 3,-0.0 0, 0.0 83,-0.0 0.000 360.0 360.0 360.0 112.1 84.2 33.8 123.6 2 51 A S + 0 0 42 86,-0.2 50,-2.2 83,-0.0 2,-0.6 0.557 360.0 96.3-120.5 -18.1 88.0 33.7 124.1 3 52 A K E -A 51 0A 6 48,-0.2 82,-2.3 85,-0.1 2,-0.4 -0.691 52.7-174.4 -86.0 120.4 88.5 31.2 127.0 4 53 A V E -AB 50 84A 3 46,-2.9 46,-2.2 -2,-0.6 2,-0.4 -0.924 11.4-151.7-119.9 133.3 89.3 27.7 125.9 5 54 A V E -AB 49 83A 4 78,-2.6 78,-2.0 -2,-0.4 2,-0.5 -0.860 5.1-164.8-104.2 140.3 89.6 24.5 127.9 6 55 A I E +AB 48 82A 0 42,-2.2 42,-1.7 -2,-0.4 76,-0.2 -0.970 30.9 170.8-121.9 112.4 91.8 21.5 127.0 7 56 A R E + B 0 81A 5 74,-2.4 74,-1.9 -2,-0.5 40,-0.2 -0.676 39.9 50.7-130.3 168.7 90.6 18.6 129.3 8 57 A R E S+ 0 0 60 38,-0.4 39,-0.2 -2,-0.2 -1,-0.2 0.806 71.0 157.4 65.8 33.5 90.9 14.8 130.0 9 58 A L E -A 46 0A 0 37,-2.6 37,-2.0 -3,-0.2 -1,-0.2 -0.460 56.5 -75.0 -76.9 157.6 94.7 15.1 129.9 10 59 A P > - 0 0 1 0, 0.0 3,-1.8 0, 0.0 -1,-0.1 -0.297 42.8-124.6 -54.4 138.7 96.9 12.5 131.7 11 60 A P T 3 S+ 0 0 29 0, 0.0 34,-0.1 0, 0.0 25,-0.1 0.647 108.4 46.4 -65.0 -18.8 96.7 13.0 135.5 12 61 A T T 3 S+ 0 0 102 34,-0.1 2,-0.2 2,-0.1 23,-0.0 0.138 82.8 118.1-109.7 15.5 100.5 13.2 135.8 13 62 A L < - 0 0 15 -3,-1.8 2,-0.3 4,-0.0 59,-0.0 -0.541 54.8-144.6 -71.5 148.6 101.1 15.6 132.9 14 63 A T > - 0 0 54 -2,-0.2 4,-2.1 1,-0.1 5,-0.2 -0.785 22.6-110.1-112.6 161.0 102.7 18.9 133.9 15 64 A K H > S+ 0 0 63 -2,-0.3 4,-2.0 1,-0.2 5,-0.1 0.894 118.4 50.4 -53.1 -44.4 102.2 22.4 132.6 16 65 A E H > S+ 0 0 121 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.910 109.2 49.1 -66.5 -45.4 105.7 22.4 131.1 17 66 A Q H > S+ 0 0 86 1,-0.2 4,-1.2 2,-0.2 -1,-0.2 0.874 110.6 52.8 -59.3 -38.8 105.3 19.1 129.3 18 67 A L H X S+ 0 0 0 -4,-2.1 4,-1.8 1,-0.2 3,-0.3 0.893 106.3 53.4 -62.4 -42.2 101.9 20.3 127.9 19 68 A Q H X S+ 0 0 74 -4,-2.0 4,-1.9 1,-0.2 -2,-0.2 0.896 103.0 56.6 -60.9 -41.9 103.7 23.4 126.6 20 69 A E H < S+ 0 0 139 -4,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.844 111.0 44.7 -59.9 -35.2 106.3 21.3 124.7 21 70 A H H < S+ 0 0 73 -4,-1.2 -1,-0.2 -3,-0.3 -2,-0.2 0.842 114.1 48.7 -74.9 -36.8 103.4 19.6 122.9 22 71 A L H < S+ 0 0 1 -4,-1.8 -2,-0.2 -5,-0.1 -1,-0.2 0.755 87.8 147.1 -79.3 -27.3 101.4 22.8 122.1 23 72 A Q < + 0 0 110 -4,-1.9 2,-0.1 -5,-0.1 -3,-0.0 -0.244 48.5 59.9 -66.7 147.4 104.2 25.0 120.7 24 73 A P S S- 0 0 103 0, 0.0 -1,-0.1 0, 0.0 -4,-0.0 0.236 88.6-157.5 -71.6 126.5 104.3 27.0 118.6 25 74 A M - 0 0 43 1,-0.1 3,-0.1 -2,-0.1 -2,-0.1 -0.536 9.7-127.5 -77.2 136.8 101.8 28.7 121.0 26 75 A P - 0 0 27 0, 0.0 2,-0.1 0, 0.0 -1,-0.1 -0.309 47.5 -69.3 -74.7 166.6 99.4 31.3 119.6 27 76 A E + 0 0 110 -2,-0.0 26,-1.5 25,-0.0 27,-0.3 -0.386 66.5 174.0 -62.1 129.5 99.1 34.8 121.3 28 77 A H E -C 52 0A 69 24,-0.2 24,-0.2 25,-0.1 3,-0.1 -0.999 39.6-156.1-144.2 142.1 97.4 34.4 124.7 29 78 A D E S+ 0 0 119 22,-2.2 2,-0.3 -2,-0.3 23,-0.1 0.848 86.9 18.2 -69.6 -42.1 96.6 36.5 127.8 30 79 A Y E +C 51 0A 58 21,-0.6 21,-1.3 2,-0.0 2,-0.2 -0.938 53.5 170.9-142.1 147.8 96.4 33.5 130.2 31 80 A F E +C 50 0A 13 -2,-0.3 2,-0.3 19,-0.2 19,-0.2 -0.656 17.1 160.8-167.3 104.3 97.6 29.9 130.4 32 81 A E E -C 49 0A 84 17,-1.6 17,-1.8 -2,-0.2 2,-0.3 -0.972 27.7-135.0-137.8 148.7 97.3 27.8 133.6 33 82 A F E -C 48 0A 36 -2,-0.3 2,-0.3 15,-0.2 15,-0.2 -0.768 20.0-175.0-107.4 139.4 97.3 24.1 134.5 34 83 A F E +C 47 0A 30 13,-2.9 13,-2.5 -2,-0.3 2,-0.3 -0.992 14.0 139.8-136.6 145.4 94.9 22.3 136.9 35 84 A S E +C 46 0A 39 -2,-0.3 11,-0.2 11,-0.2 -23,-0.0 -0.964 49.1 45.1-164.0 177.6 94.6 18.7 138.3 36 85 A N S S+ 0 0 111 9,-0.5 10,-0.1 -2,-0.3 -1,-0.1 0.791 80.8 107.8 49.3 37.2 93.9 16.6 141.4 37 86 A D + 0 0 18 8,-0.3 -1,-0.1 101,-0.0 139,-0.1 0.320 43.6 115.2-126.5 7.6 90.8 18.7 142.2 38 87 A T - 0 0 22 7,-0.2 3,-0.2 1,-0.1 101,-0.1 -0.325 58.4-143.7 -77.1 159.9 87.8 16.4 141.4 39 88 A S S S+ 0 0 3 99,-0.1 -1,-0.1 1,-0.1 152,-0.1 0.274 89.1 77.4 -95.5 7.7 85.2 15.0 143.7 40 89 A L S > S- 0 0 1 3,-0.2 3,-2.2 151,-0.0 -1,-0.1 -0.145 79.1-159.2-118.7 38.0 85.1 11.7 141.7 41 90 A Y T 3 S+ 0 0 167 1,-0.3 -2,-0.0 -3,-0.2 0, 0.0 -0.303 71.1 32.8 -53.4 140.1 88.3 9.8 142.7 42 91 A P T 3 S+ 0 0 75 0, 0.0 2,-1.7 0, 0.0 -1,-0.3 -0.903 99.2 88.3 -92.2 25.4 89.8 7.6 141.3 43 92 A H < + 0 0 47 -3,-2.2 2,-0.5 2,-0.0 -3,-0.2 -0.581 64.8 179.3 -83.7 83.2 88.8 9.2 138.0 44 93 A M + 0 0 35 -2,-1.7 2,-0.3 -8,-0.1 -9,-0.0 -0.756 9.6 158.0 -99.7 125.0 91.8 11.6 137.7 45 94 A Y - 0 0 57 -2,-0.5 -9,-0.5 -35,-0.1 -8,-0.3 -0.925 26.4-139.6-137.8 162.4 92.4 13.9 134.9 46 95 A A E +AC 9 35A 0 -37,-2.0 -37,-2.6 -2,-0.3 -38,-0.4 -0.801 23.6 172.5-119.5 161.5 94.4 17.2 134.2 47 96 A R E - C 0 34A 7 -13,-2.5 -13,-2.9 -2,-0.3 2,-0.3 -0.963 15.1-148.0-161.2 171.6 93.3 20.2 132.2 48 97 A A E -AC 6 33A 0 -42,-1.7 -42,-2.2 -2,-0.3 2,-0.4 -0.985 7.6-142.0-150.7 156.8 94.2 23.8 131.2 49 98 A Y E -AC 5 32A 5 -17,-1.8 -17,-1.6 -2,-0.3 2,-0.4 -0.973 15.6-176.9-123.2 139.2 92.7 27.1 130.2 50 99 A I E -AC 4 31A 1 -46,-2.2 -46,-2.9 -2,-0.4 2,-0.7 -0.999 16.3-150.6-134.6 131.6 94.0 29.5 127.6 51 100 A N E -AC 3 30A 17 -21,-1.3 -22,-2.2 -2,-0.4 -21,-0.6 -0.908 22.9-149.6-106.8 108.4 92.5 32.9 126.8 52 101 A F E - C 0 28A 5 -50,-2.2 -24,-0.2 -2,-0.7 3,-0.1 -0.409 11.8-147.1 -81.0 152.0 93.2 33.6 123.1 53 102 A K S S+ 0 0 122 -26,-1.5 2,-0.3 -2,-0.1 -1,-0.1 0.840 81.8 35.4 -85.8 -39.9 93.7 37.1 121.6 54 103 A N S S- 0 0 55 -27,-0.3 4,-0.4 1,-0.1 3,-0.1 -0.861 71.2-134.5-116.9 155.7 92.2 36.5 118.1 55 104 A Q S >> S+ 0 0 138 -2,-0.3 4,-1.0 1,-0.2 3,-0.9 0.821 100.8 58.5 -77.4 -35.6 89.2 34.4 117.0 56 105 A E H 3> S+ 0 0 138 1,-0.2 4,-1.3 2,-0.2 -1,-0.2 0.783 98.9 61.2 -67.8 -26.7 90.8 32.7 114.0 57 106 A D H 3> S+ 0 0 40 1,-0.2 4,-1.6 2,-0.2 -1,-0.2 0.716 97.2 59.5 -69.6 -24.3 93.5 31.2 116.1 58 107 A I H <> S+ 0 0 14 -3,-0.9 4,-1.8 -4,-0.4 5,-0.2 0.909 102.7 50.0 -71.1 -45.7 91.0 29.3 118.2 59 108 A I H X S+ 0 0 81 -4,-1.0 4,-1.7 1,-0.2 -2,-0.2 0.902 112.1 49.4 -59.4 -42.8 89.7 27.3 115.2 60 109 A L H X S+ 0 0 115 -4,-1.3 4,-1.4 1,-0.2 -1,-0.2 0.897 107.7 55.0 -60.9 -41.8 93.3 26.4 114.3 61 110 A F H X S+ 0 0 9 -4,-1.6 4,-2.1 1,-0.2 -2,-0.2 0.847 111.2 41.6 -65.7 -37.8 94.1 25.3 117.8 62 111 A R H X S+ 0 0 32 -4,-1.8 4,-1.6 2,-0.2 -1,-0.2 0.783 108.6 59.5 -84.3 -26.3 91.2 22.8 118.1 63 112 A D H < S+ 0 0 80 -4,-1.7 -2,-0.2 -5,-0.2 -1,-0.2 0.855 116.4 37.7 -57.7 -35.2 91.8 21.5 114.5 64 113 A R H < S+ 0 0 129 -4,-1.4 -2,-0.2 -5,-0.1 -1,-0.2 0.868 129.8 23.6 -85.9 -41.3 95.3 20.7 115.8 65 114 A F H >< S+ 0 0 3 -4,-2.1 3,-1.1 -5,-0.1 2,-0.7 0.513 84.9 105.2-116.0 -8.2 94.8 19.4 119.4 66 115 A D T 3< S+ 0 0 50 -4,-1.6 15,-0.2 1,-0.2 3,-0.1 -0.686 103.3 8.9 -73.4 115.7 91.2 18.1 119.7 67 116 A G T 3 S+ 0 0 40 13,-1.9 -1,-0.2 -2,-0.7 2,-0.1 0.291 91.2 149.8 93.3 -8.1 91.7 14.3 119.7 68 117 A Y < - 0 0 85 -3,-1.1 12,-1.7 11,-0.1 2,-0.7 -0.395 48.0-125.0 -58.5 126.2 95.5 14.7 120.0 69 118 A V E -D 79 0B 64 10,-0.2 2,-0.2 -2,-0.1 -1,-0.1 -0.685 28.3-173.4 -88.0 112.7 96.7 11.6 121.9 70 119 A F E -D 78 0B 2 8,-2.1 8,-1.9 -2,-0.7 2,-0.3 -0.637 11.9-146.5 -89.9 158.6 98.8 12.3 125.0 71 120 A L E -D 77 0B 107 -2,-0.2 2,-0.2 6,-0.2 6,-0.2 -0.933 3.9-148.6-125.0 150.5 100.5 9.4 126.9 72 121 A D > - 0 0 28 4,-1.0 3,-1.3 -2,-0.3 6,-0.0 -0.433 48.7 -80.5 -97.6-175.1 101.2 8.8 130.6 73 122 A N T 3 S+ 0 0 150 1,-0.2 -2,-0.0 -2,-0.2 -1,-0.0 0.900 127.7 50.3 -51.6 -46.9 104.3 6.8 131.8 74 123 A K T 3 S- 0 0 176 1,-0.1 -1,-0.2 2,-0.0 -3,-0.0 0.413 116.3-106.3 -83.9 1.1 102.6 3.3 131.3 75 124 A G < + 0 0 49 -3,-1.3 2,-0.2 1,-0.3 -2,-0.1 0.583 64.3 152.2 88.6 11.8 101.5 4.0 127.7 76 125 A Q - 0 0 94 1,-0.1 -4,-1.0 2,-0.0 -1,-0.3 -0.553 45.9-118.0 -72.7 138.9 97.8 4.4 128.3 77 126 A E E -D 71 0B 149 -2,-0.2 -6,-0.2 -6,-0.2 -1,-0.1 -0.581 27.8-174.6 -85.1 141.6 96.2 6.6 125.6 78 127 A Y E -D 70 0B 32 -8,-1.9 -8,-2.1 -2,-0.2 2,-0.3 -0.784 9.7-159.4-135.8 86.4 94.5 9.9 126.6 79 128 A P E -D 69 0B 74 0, 0.0 -10,-0.2 0, 0.0 2,-0.1 -0.545 23.0-134.1 -61.7 126.6 92.7 11.7 123.7 80 129 A A - 0 0 2 -12,-1.7 -13,-1.9 -2,-0.3 2,-0.4 -0.452 9.1-142.4 -81.0 157.8 92.3 15.4 124.7 81 130 A I E -B 7 0A 43 -74,-1.9 -74,-2.4 -15,-0.2 2,-0.5 -0.990 11.2-164.8-120.3 134.2 89.1 17.4 124.3 82 131 A V E +B 6 0A 11 -2,-0.4 2,-0.3 -76,-0.2 -76,-0.2 -0.980 25.9 138.8-122.7 120.2 89.2 21.1 123.3 83 132 A E E -B 5 0A 79 -78,-2.0 -78,-2.6 -2,-0.5 2,-0.2 -0.928 59.1 -78.0-144.1 166.6 86.1 23.2 123.8 84 133 A F E -B 4 0A 51 -2,-0.3 -80,-0.3 -80,-0.2 4,-0.1 -0.526 60.5-103.0 -62.4 137.2 85.1 26.7 124.9 85 134 A A - 0 0 2 -82,-2.3 -82,-0.1 -2,-0.2 -1,-0.1 -0.399 20.9-131.1 -58.3 139.6 85.2 26.9 128.7 86 135 A P S S+ 0 0 41 0, 0.0 2,-0.5 0, 0.0 -1,-0.1 0.736 101.2 48.5 -67.8 -22.2 81.7 26.7 130.3 87 136 A F S S- 0 0 17 2,-0.1 -2,-0.1 1,-0.1 121,-0.0 -0.989 72.4-167.0-117.5 122.2 82.6 29.7 132.5 88 137 A Q + 0 0 45 -2,-0.5 2,-0.3 2,-0.1 -86,-0.2 0.476 46.3 116.8 -94.0 -1.1 84.2 32.5 130.4 89 138 A K 0 0 104 78,-0.1 -2,-0.1 1,-0.1 0, 0.0 -0.499 360.0 360.0 -73.6 130.3 85.6 34.7 133.3 90 139 A A 0 0 70 -2,-0.3 -1,-0.1 -87,-0.0 -2,-0.1 -0.653 360.0 360.0 -91.4 360.0 89.5 35.0 133.2 91 !* 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 92 768 B R 0 0 170 0, 0.0 5,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 126.1 97.2 15.4 158.2 93 769 B P >> - 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