==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=18-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE 02-MAR-04 1UYH . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR L.WRIGHT,X.BARRIL,B.DYMOCK,L.SHERIDAN,A.SURGENOR,M.BESWICK, . 208 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10889.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 159 76.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 41 19.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 16 7.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 33 15.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 57 27.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 2.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 0 0 1 1 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 2 0 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A E 0 0 199 0, 0.0 2,-0.6 0, 0.0 158,-0.3 0.000 360.0 360.0 360.0 148.7 6.9 29.0 38.2 2 17 A V - 0 0 69 156,-0.1 2,-0.5 154,-0.1 156,-0.2 -0.828 360.0-155.5 -99.7 119.9 8.1 27.8 34.8 3 18 A E E -A 157 0A 68 154,-2.5 154,-1.8 -2,-0.6 2,-0.5 -0.829 5.8-152.7 -93.0 130.4 10.8 25.1 34.7 4 19 A T E -A 156 0A 95 -2,-0.5 2,-0.3 152,-0.2 152,-0.2 -0.885 15.2-177.4-105.1 133.0 12.9 24.9 31.6 5 20 A F E -A 155 0A 50 150,-3.5 150,-2.5 -2,-0.5 2,-0.3 -0.925 23.7-124.0-126.3 146.5 14.5 21.5 30.6 6 21 A A E -A 154 0A 81 -2,-0.3 148,-0.2 148,-0.2 2,-0.2 -0.675 28.4-119.2 -79.6 141.5 16.9 20.5 27.8 7 22 A F - 0 0 21 146,-2.0 2,-0.1 -2,-0.3 -1,-0.0 -0.560 41.0 -97.0 -68.4 143.6 15.8 17.6 25.4 8 23 A Q >> - 0 0 116 -2,-0.2 4,-2.0 1,-0.1 3,-0.9 -0.466 44.2-104.3 -56.1 137.6 18.2 14.7 25.5 9 24 A A H 3> S+ 0 0 67 1,-0.2 4,-1.6 2,-0.2 5,-0.1 0.780 117.9 54.8 -31.1 -47.3 20.6 15.2 22.6 10 25 A E H 3> S+ 0 0 60 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.874 109.1 45.8 -64.0 -42.8 19.0 12.4 20.4 11 26 A I H <> S+ 0 0 2 -3,-0.9 4,-3.9 2,-0.2 -2,-0.2 0.910 110.3 53.7 -65.9 -46.3 15.4 13.8 20.6 12 27 A A H X S+ 0 0 27 -4,-2.0 4,-2.5 2,-0.2 -2,-0.2 0.885 111.4 47.9 -52.6 -42.8 16.7 17.3 19.9 13 28 A Q H X S+ 0 0 118 -4,-1.6 4,-2.0 -5,-0.2 -2,-0.2 0.853 111.7 47.9 -67.0 -43.9 18.3 15.7 16.8 14 29 A L H X S+ 0 0 0 -4,-2.3 4,-2.8 2,-0.2 5,-0.3 0.966 111.4 52.7 -61.1 -48.5 15.1 13.9 15.8 15 30 A M H X S+ 0 0 4 -4,-3.9 4,-2.3 1,-0.2 -2,-0.2 0.935 109.6 46.9 -54.5 -50.4 13.3 17.2 16.3 16 31 A S H X S+ 0 0 62 -4,-2.5 4,-3.0 2,-0.2 -1,-0.2 0.872 111.2 52.6 -55.4 -44.8 15.7 19.1 13.9 17 32 A L H X S+ 0 0 48 -4,-2.0 4,-2.9 2,-0.2 -2,-0.2 0.979 108.8 48.4 -57.7 -57.1 15.4 16.3 11.4 18 33 A I H < S+ 0 0 1 -4,-2.8 -2,-0.2 1,-0.2 -1,-0.2 0.899 117.7 43.2 -49.3 -43.4 11.6 16.5 11.4 19 34 A I H < S+ 0 0 67 -4,-2.3 -1,-0.2 -5,-0.3 -2,-0.2 0.918 122.4 36.6 -68.8 -38.2 11.9 20.3 11.0 20 35 A N H < S+ 0 0 124 -4,-3.0 -2,-0.2 -5,-0.2 -3,-0.2 0.777 89.1 94.4 -91.8 -36.4 14.6 20.3 8.4 21 36 A T S < S- 0 0 61 -4,-2.9 2,-0.5 -5,-0.2 -4,-0.0 -0.361 79.6-115.5 -61.5 136.3 14.1 17.4 6.0 22 37 A F + 0 0 186 -2,-0.0 2,-0.2 2,-0.0 -1,-0.1 -0.689 55.6 148.8 -68.7 120.1 12.2 18.1 2.8 23 38 A Y - 0 0 33 -2,-0.5 3,-0.1 105,-0.1 -2,-0.0 -0.681 28.8-173.2-161.3 99.1 9.0 16.0 3.1 24 39 A S S S+ 0 0 91 1,-0.2 2,-2.7 -2,-0.2 3,-0.3 0.758 70.4 84.4 -70.4 -26.9 5.6 17.0 1.7 25 40 A N > + 0 0 60 1,-0.2 3,-1.1 2,-0.1 -1,-0.2 -0.211 50.2 144.8 -74.4 52.8 3.5 14.3 3.2 26 41 A K T > + 0 0 35 -2,-2.7 3,-1.8 1,-0.2 -1,-0.2 0.754 46.1 85.1 -64.3 -22.8 3.1 16.3 6.4 27 42 A E T >> + 0 0 18 -3,-0.3 3,-1.2 1,-0.3 4,-0.6 0.617 66.7 81.7 -60.3 -15.5 -0.5 15.1 7.1 28 43 A I H <> + 0 0 0 -3,-1.1 4,-1.6 1,-0.2 -1,-0.3 0.620 69.5 84.5 -67.0 -6.1 0.6 12.0 8.8 29 44 A F H <> S+ 0 0 0 -3,-1.8 4,-2.0 1,-0.2 -1,-0.2 0.903 86.6 55.5 -61.7 -39.3 1.0 14.1 12.0 30 45 A L H <> S+ 0 0 0 -3,-1.2 4,-2.4 1,-0.2 5,-0.2 0.932 104.7 48.8 -64.6 -48.5 -2.7 13.6 12.8 31 46 A R H X S+ 0 0 57 -4,-0.6 4,-2.6 1,-0.2 -1,-0.2 0.897 109.7 54.0 -59.7 -34.4 -2.7 9.8 12.7 32 47 A E H X S+ 0 0 11 -4,-1.6 4,-1.3 1,-0.2 -1,-0.2 0.906 111.4 43.9 -64.6 -44.2 0.3 9.7 15.0 33 48 A L H X S+ 0 0 4 -4,-2.0 4,-1.9 2,-0.2 -1,-0.2 0.849 114.5 49.9 -67.6 -40.2 -1.4 11.9 17.6 34 49 A I H X S+ 0 0 0 -4,-2.4 4,-2.9 2,-0.2 -2,-0.2 0.887 109.6 50.9 -64.4 -45.0 -4.7 10.0 17.3 35 50 A S H X S+ 0 0 46 -4,-2.6 4,-2.0 2,-0.2 -2,-0.2 0.805 108.5 52.4 -61.4 -31.6 -2.9 6.6 17.7 36 51 A N H X S+ 0 0 61 -4,-1.3 4,-2.1 2,-0.2 -2,-0.2 0.903 110.6 48.0 -71.9 -45.3 -1.2 8.0 20.8 37 52 A S H X S+ 0 0 3 -4,-1.9 4,-2.4 2,-0.2 -2,-0.2 0.943 109.9 53.0 -55.1 -50.2 -4.6 9.0 22.2 38 53 A S H X S+ 0 0 19 -4,-2.9 4,-2.4 1,-0.2 -2,-0.2 0.911 108.6 48.9 -53.9 -46.0 -5.9 5.5 21.3 39 54 A D H X S+ 0 0 92 -4,-2.0 4,-1.2 1,-0.2 -1,-0.2 0.901 112.8 48.6 -61.8 -43.0 -3.1 3.8 23.3 40 55 A A H X S+ 0 0 19 -4,-2.1 4,-1.8 2,-0.2 41,-1.5 0.824 111.2 48.4 -62.2 -38.3 -3.8 6.1 26.3 41 56 A L H X S+ 0 0 0 -4,-2.4 4,-2.4 39,-0.3 -2,-0.2 0.935 110.4 52.4 -70.4 -47.5 -7.6 5.4 26.2 42 57 A D H X S+ 0 0 60 -4,-2.4 4,-3.1 -5,-0.2 -1,-0.2 0.825 109.2 52.1 -42.0 -44.6 -6.9 1.6 26.0 43 58 A K H X S+ 0 0 116 -4,-1.2 4,-2.6 2,-0.2 -2,-0.2 0.925 111.0 42.2 -74.9 -47.2 -4.7 1.9 29.0 44 59 A I H X S+ 0 0 0 -4,-1.8 4,-1.7 2,-0.2 -1,-0.2 0.836 114.7 55.3 -65.9 -34.4 -7.1 3.7 31.3 45 60 A R H X S+ 0 0 126 -4,-2.4 4,-0.7 -5,-0.2 -2,-0.2 0.968 110.5 43.9 -56.5 -54.2 -9.7 1.3 29.9 46 61 A Y H >< S+ 0 0 174 -4,-3.1 3,-1.1 1,-0.2 4,-0.5 0.925 112.6 52.6 -57.5 -47.9 -7.5 -1.7 31.0 47 62 A E H >< S+ 0 0 48 -4,-2.6 3,-0.6 1,-0.3 -1,-0.2 0.783 103.8 55.6 -63.9 -33.4 -6.7 -0.2 34.4 48 63 A S H >< S+ 0 0 17 -4,-1.7 3,-1.0 -3,-0.2 -1,-0.3 0.679 88.0 77.7 -73.5 -15.8 -10.3 0.4 35.5 49 64 A L T << S+ 0 0 138 -3,-1.1 -1,-0.2 -4,-0.7 -2,-0.2 0.870 109.0 29.1 -59.7 -37.0 -11.3 -3.2 34.9 50 65 A T T < S+ 0 0 123 -3,-0.6 -1,-0.3 -4,-0.5 -2,-0.2 0.148 136.5 30.6-107.7 13.1 -9.7 -4.1 38.2 51 66 A D X - 0 0 58 -3,-1.0 3,-1.6 1,-0.0 -1,-0.2 -0.423 59.8-176.9-168.5 87.3 -10.3 -0.6 39.8 52 67 A P G > S+ 0 0 91 0, 0.0 3,-1.4 0, 0.0 -4,-0.1 0.611 78.0 75.6 -63.9 -14.9 -13.4 1.3 38.6 53 68 A S G > S+ 0 0 62 1,-0.3 3,-1.4 2,-0.2 4,-0.3 0.627 76.5 75.4 -73.4 -15.5 -12.5 4.3 40.8 54 69 A K G < S+ 0 0 58 -3,-1.6 -1,-0.3 1,-0.2 3,-0.2 0.603 92.8 57.0 -69.4 -9.6 -9.8 5.2 38.2 55 70 A L G X S+ 0 0 31 -3,-1.4 3,-1.5 1,-0.1 -1,-0.2 0.303 74.1 97.0 -99.7 6.6 -12.8 6.4 36.1 56 71 A D T < S+ 0 0 123 -3,-1.4 3,-0.2 1,-0.3 -1,-0.1 0.830 78.5 61.1 -64.8 -31.3 -14.2 8.9 38.8 57 72 A S T 3 S- 0 0 36 -4,-0.3 -1,-0.3 1,-0.3 -2,-0.1 0.177 132.4 -30.0 -78.7 15.6 -12.4 11.8 36.9 58 73 A G < - 0 0 31 -3,-1.5 -1,-0.3 108,-0.1 -2,-0.0 -0.041 44.8-155.0 136.0 126.6 -14.5 11.0 33.8 59 74 A K + 0 0 151 -3,-0.2 2,-0.3 -2,-0.1 -3,-0.1 0.696 67.3 98.3 -92.7 -25.1 -16.2 7.9 32.3 60 75 A E - 0 0 123 -5,-0.1 2,-0.6 1,-0.1 0, 0.0 -0.527 55.3-161.7 -70.2 129.3 -16.3 9.0 28.6 61 76 A L + 0 0 31 -2,-0.3 2,-0.3 17,-0.1 19,-0.1 -0.909 40.0 122.6-114.1 97.9 -13.4 7.5 26.5 62 77 A H - 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0 0 5 85,-0.2 2,-0.4 57,-0.2 57,-0.2 -0.063 16.7 -83.7 84.6 166.9 -3.0 11.3 31.1 83 98 A M - 0 0 37 85,-0.4 56,-0.4 62,-0.1 62,-0.2 -0.935 27.9-142.0-117.1 133.5 0.7 12.0 31.9 84 99 A T > - 0 0 26 -2,-0.4 4,-2.0 54,-0.1 5,-0.1 -0.338 35.2-105.3 -75.9 168.5 2.4 12.5 35.3 85 100 A K H > S+ 0 0 67 2,-0.2 4,-2.0 1,-0.2 5,-0.3 0.838 124.4 58.1 -60.4 -37.0 5.2 15.1 35.8 86 101 A A H >>S+ 0 0 46 2,-0.2 4,-2.5 1,-0.2 5,-2.5 0.938 104.5 50.3 -56.2 -50.3 7.6 12.2 35.8 87 102 A D H 4>S+ 0 0 37 4,-0.2 5,-2.4 3,-0.2 6,-0.4 0.974 113.4 46.1 -49.1 -58.8 6.4 11.2 32.3 88 103 A L H <5S+ 0 0 13 -4,-2.0 -2,-0.2 1,-0.2 -1,-0.2 0.802 122.4 31.5 -56.4 -36.1 6.9 14.8 31.0 89 104 A I H <5S- 0 0 43 -4,-2.0 -1,-0.2 -5,-0.1 -2,-0.2 0.731 137.6 -4.6-105.3 -32.6 10.3 15.4 32.4 90 105 A N T X5S+ 0 0 106 -4,-2.5 4,-2.0 -5,-0.3 -3,-0.2 0.614 119.2 56.1-130.4 -52.6 12.2 12.1 32.5 91 106 A N H > S+ 0 0 24 -6,-0.4 4,-1.0 2,-0.2 -1,-0.2 0.792 108.9 56.3 -66.4 -31.6 12.5 11.1 27.0 94 109 A T H >< S+ 0 0 82 -4,-2.0 3,-0.5 2,-0.2 4,-0.5 0.969 112.2 38.9 -65.2 -50.1 14.0 8.0 28.4 95 110 A I H 3X S+ 0 0 128 -4,-2.3 4,-0.9 1,-0.2 3,-0.5 0.848 110.1 62.0 -71.4 -32.3 11.9 5.6 26.3 96 111 A A H 3X S+ 0 0 8 -4,-2.0 4,-3.1 -5,-0.3 -1,-0.2 0.772 86.7 75.5 -64.0 -28.9 12.1 7.8 23.2 97 112 A K H S+ 0 0 84 -3,-0.5 4,-2.3 -4,-0.5 5,-0.2 0.849 115.8 50.1 -62.8 -41.2 15.9 3.9 21.6 99 114 A G H X S+ 0 0 10 -4,-0.9 4,-2.8 1,-0.2 -2,-0.2 0.895 110.4 52.7 -68.4 -38.7 12.9 4.6 19.3 100 115 A T H X S+ 0 0 1 -4,-3.1 4,-3.3 2,-0.2 -2,-0.2 0.943 110.0 46.3 -56.7 -52.1 14.7 7.7 18.1 101 116 A K H X S+ 0 0 126 -4,-1.9 4,-1.9 2,-0.2 -2,-0.2 0.937 114.4 46.8 -61.6 -53.7 18.0 5.8 17.2 102 117 A A H >X S+ 0 0 38 -4,-2.3 4,-2.4 2,-0.2 3,-0.6 0.965 115.0 47.9 -45.6 -56.1 16.1 2.9 15.5 103 118 A F H 3X S+ 0 0 0 -4,-2.8 4,-1.7 1,-0.2 -2,-0.2 0.945 110.7 50.8 -56.4 -49.3 14.1 5.5 13.5 104 119 A M H 3< S+ 0 0 41 -4,-3.3 -1,-0.2 1,-0.2 -2,-0.2 0.759 111.2 47.9 -64.5 -26.8 17.1 7.5 12.6 105 120 A E H X< S+ 0 0 103 -4,-1.9 3,-1.5 -3,-0.6 -1,-0.2 0.897 107.5 55.7 -77.4 -41.1 19.0 4.5 11.3 106 121 A A H 3X>S+ 0 0 22 -4,-2.4 5,-2.1 1,-0.3 4,-0.6 0.829 85.2 78.0 -60.3 -36.2 16.0 3.3 9.2 107 122 A L T 3<5S+ 0 0 41 -4,-1.7 2,-0.4 -5,-0.2 -1,-0.3 0.623 99.5 54.2 -54.9 -4.0 15.8 6.6 7.4 108 123 A Q T <45S+ 0 0 145 -3,-1.5 -1,-0.2 1,-0.1 4,-0.1 -0.949 90.0 56.5-139.5 114.4 18.7 4.9 5.7 109 124 A A T 45S- 0 0 109 -2,-0.4 -2,-0.1 2,-0.1 -1,-0.1 -0.208 139.6 -73.2 134.6 -20.6 18.1 1.5 4.3 110 125 A G T <5S+ 0 0 64 -4,-0.6 -3,-0.2 1,-0.2 -2,-0.1 0.324 88.5 142.8 123.8 -3.1 15.5 3.5 2.6 111 126 A A < - 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