==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER RECEPTOR 06-JUL-07 2V5O . COMPND 2 MOLECULE: CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR J.BROWN,C.DELAINE,O.J.ZACCHEO,C.SIEBOLD,R.J.GILBERT,G.VAN BO . 604 3 18 16 2 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 31382.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 366 60.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 38 6.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 182 30.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 7 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 5 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 9 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 65 10.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 46 7.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 14 2.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 9 5 11 4 9 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 4 3 4 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1516 A a 0 0 28 0, 0.0 13,-1.4 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0 34.7 47.5 -19.6 16.0 2 1517 A Q E -A 13 0A 133 62,-0.3 64,-0.3 11,-0.2 2,-0.3 -0.987 360.0-174.1-147.9 150.6 50.5 -18.5 13.9 3 1518 A V E -A 12 0A 25 9,-1.0 9,-1.2 -2,-0.3 2,-0.2 -0.961 9.9-153.7-140.5 157.5 51.4 -16.7 10.6 4 1519 A T E -A 11 0A 83 -2,-0.3 7,-0.2 7,-0.2 64,-0.1 -0.723 28.6 -89.2-124.9 178.8 54.6 -16.1 8.6 5 1520 A N > - 0 0 10 5,-0.6 4,-1.1 -2,-0.2 6,-0.0 -0.794 17.1-149.6 -98.3 126.4 55.9 -13.5 6.2 6 1521 A P T 4 S+ 0 0 116 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 0.701 100.1 33.7 -60.4 -22.3 55.4 -13.8 2.4 7 1522 A S T 4 S+ 0 0 104 3,-0.0 -2,-0.0 0, 0.0 0, 0.0 0.694 136.0 16.7-109.8 -26.8 58.7 -12.0 1.7 8 1523 A T T 4 S- 0 0 87 2,-0.1 -4,-0.0 0, 0.0 0, 0.0 0.660 85.3-133.9-116.2 -30.7 61.1 -13.0 4.6 9 1524 A G < + 0 0 53 -4,-1.1 2,-0.2 1,-0.2 -5,-0.0 0.840 41.6 168.8 74.5 35.3 59.4 -16.1 6.1 10 1525 A H - 0 0 72 1,-0.1 -5,-0.6 0, 0.0 2,-0.3 -0.575 34.5-113.5 -81.7 145.0 59.8 -14.9 9.7 11 1526 A L E -A 4 0A 114 -2,-0.2 2,-0.4 -7,-0.2 -7,-0.2 -0.602 28.7-174.0 -83.8 132.7 58.0 -16.8 12.4 12 1527 A F E -A 3 0A 7 -9,-1.2 -9,-1.0 -2,-0.3 2,-0.4 -0.998 4.5-176.1-124.7 128.8 55.2 -15.1 14.5 13 1528 A D E +A 2 0A 66 -2,-0.4 3,-0.2 116,-0.4 -11,-0.2 -0.983 18.8 177.5-131.3 124.7 53.7 -16.9 17.5 14 1529 A L > + 0 0 0 -13,-1.4 3,-1.0 -2,-0.4 4,-0.4 -0.054 49.7 114.4-113.2 30.3 50.8 -15.8 19.7 15 1530 A S G > + 0 0 60 1,-0.2 3,-1.5 2,-0.2 -1,-0.2 0.872 68.8 65.5 -64.8 -38.3 50.6 -18.8 21.9 16 1531 A S G 3 S+ 0 0 82 1,-0.3 -1,-0.2 -3,-0.2 -2,-0.1 0.674 106.8 44.1 -58.6 -16.6 51.7 -16.7 24.9 17 1532 A L G < S+ 0 0 17 -3,-1.0 2,-2.5 1,-0.1 20,-0.6 0.526 81.1 105.3-103.8 -10.1 48.3 -14.8 24.5 18 1533 A S < + 0 0 60 -3,-1.5 -1,-0.1 -4,-0.4 2,-0.1 -0.201 49.0 157.2 -76.9 51.8 46.1 -17.9 23.9 19 1534 A G - 0 0 32 -2,-2.5 18,-0.4 1,-0.1 4,-0.1 -0.368 44.6-150.5 -73.3 151.2 44.4 -17.8 27.3 20 1535 A R S S+ 0 0 156 2,-0.1 22,-2.1 16,-0.1 -1,-0.1 0.774 107.5 51.4 -83.4 -34.7 41.0 -19.3 28.1 21 1536 A A S S+ 0 0 63 20,-0.2 14,-0.1 1,-0.2 22,-0.1 0.801 96.4 172.0 -66.3 -32.3 40.7 -16.6 30.8 22 1537 A G - 0 0 18 15,-0.1 14,-0.3 -5,-0.1 2,-0.2 -0.137 25.4 -72.5 62.9-147.2 41.6 -14.2 28.0 23 1538 A F E -B 35 0B 68 12,-3.3 12,-2.6 -4,-0.1 2,-0.4 -0.799 27.9-117.8-144.1 176.7 41.4 -10.4 28.4 24 1539 A T E -B 34 0B 45 -2,-0.2 2,-0.3 10,-0.2 10,-0.2 -0.993 19.0-176.5-130.5 130.1 39.2 -7.3 28.6 25 1540 A A E -B 33 0B 3 8,-2.6 8,-2.9 -2,-0.4 2,-0.3 -0.891 22.2-129.4-116.3 153.8 38.9 -4.3 26.3 26 1541 A A E -B 32 0B 18 -2,-0.3 85,-0.8 83,-0.3 2,-0.3 -0.756 20.8-179.6-105.3 150.3 36.7 -1.3 26.9 27 1542 A Y E > -B 31 0B 63 4,-1.2 4,-0.7 -2,-0.3 374,-0.0 -0.965 65.5 -10.6-139.7 149.5 34.1 0.5 24.8 28 1543 A S T 4 S- 0 0 79 -2,-0.3 373,-0.2 2,-0.1 -2,-0.0 -0.162 108.0 -58.1 48.1-153.5 32.2 3.6 26.0 29 1544 A E T 4 S+ 0 0 175 1,-0.1 372,-0.1 371,-0.1 -1,-0.1 0.977 129.2 7.5 -85.3 -64.9 32.6 4.4 29.7 30 1545 A K T 4 S+ 0 0 197 370,-0.1 2,-0.2 -4,-0.1 -2,-0.1 0.263 102.5 114.0-104.7 8.5 31.4 1.3 31.7 31 1546 A G E < -B 27 0B 11 -4,-0.7 -4,-1.2 22,-0.1 2,-0.3 -0.540 46.9-168.6 -77.0 147.4 31.0 -0.9 28.7 32 1547 A L E -B 26 0B 55 -6,-0.2 21,-1.6 -2,-0.2 2,-0.4 -0.948 18.2-154.1-138.1 154.2 33.3 -3.9 28.4 33 1548 A V E -BC 25 52B 3 -8,-2.9 -8,-2.6 -2,-0.3 2,-0.5 -0.983 12.0-153.2-131.0 121.4 34.4 -6.6 25.8 34 1549 A Y E +BC 24 51B 58 17,-1.6 17,-1.7 -2,-0.4 2,-0.3 -0.808 24.8 171.0 -93.8 132.0 35.7 -10.0 26.9 35 1550 A M E -BC 23 50B 0 -12,-2.6 -12,-3.3 -2,-0.5 2,-0.3 -0.999 22.8-159.7-146.7 142.5 38.0 -11.7 24.5 36 1551 A S - 0 0 0 13,-2.0 2,-0.5 3,-0.3 3,-0.3 -0.805 25.6-119.8-111.8 160.1 40.4 -14.6 24.1 37 1552 A I S S- 0 0 1 -20,-0.6 -15,-0.1 -18,-0.4 27,-0.1 -0.880 88.8 -11.2-103.2 128.0 43.2 -15.2 21.6 38 1553 A a S S+ 0 0 13 -2,-0.5 2,-0.3 25,-0.3 -1,-0.2 0.877 130.7 46.9 51.3 45.8 43.0 -18.2 19.2 39 1554 A G S S- 0 0 26 -3,-0.3 -3,-0.3 24,-0.2 2,-0.2 -0.908 96.5 -65.7 166.6 165.3 40.1 -19.7 21.2 40 1555 A E - 0 0 69 -2,-0.3 2,-0.4 22,-0.1 9,-0.3 -0.515 47.3-121.7 -77.5 138.9 36.8 -19.1 22.9 41 1556 A N > - 0 0 0 7,-2.1 3,-2.6 -2,-0.2 7,-0.2 -0.671 12.8-133.8 -83.9 131.0 36.6 -16.7 26.0 42 1557 A E T 3 S+ 0 0 92 -22,-2.1 -1,-0.1 -2,-0.4 -21,-0.1 0.635 104.6 59.3 -61.5 -14.7 35.2 -18.3 29.1 43 1558 A N T 3 S+ 0 0 63 -22,-0.1 -1,-0.3 2,-0.1 13,-0.1 0.491 101.3 66.1 -90.2 -5.9 33.0 -15.3 29.7 44 1559 A b S < S- 0 0 10 -3,-2.6 3,-0.1 4,-0.2 4,-0.1 -0.646 100.4 -78.5-107.7 165.7 31.2 -15.8 26.4 45 1560 A P S > S- 0 0 50 0, 0.0 3,-0.8 0, 0.0 -4,-0.2 -0.320 70.7 -73.7 -58.2 150.0 28.9 -18.5 25.1 46 1561 A P T 3 S+ 0 0 117 0, 0.0 3,-0.1 0, 0.0 -4,-0.1 -0.260 122.0 24.3 -54.9 117.7 30.7 -21.7 23.9 47 1562 A G T 3 S+ 0 0 31 1,-0.3 2,-0.4 -3,-0.1 15,-0.1 0.686 93.9 116.5 101.2 26.1 32.4 -21.0 20.6 48 1563 A V < - 0 0 8 -3,-0.8 -7,-2.1 13,-0.3 13,-0.3 -0.988 45.5-164.8-132.3 125.4 32.8 -17.3 20.8 49 1564 A G S S+ 0 0 0 11,-1.1 -13,-2.0 -2,-0.4 2,-0.3 0.887 78.1 9.4 -73.4 -42.5 36.1 -15.3 20.9 50 1565 A A E +CD 35 60B 0 10,-1.3 9,-2.1 -15,-0.2 10,-0.5 -0.996 64.9 175.5-144.1 147.7 34.7 -12.0 22.1 51 1566 A b E -CD 34 58B 0 -17,-1.7 -17,-1.6 -2,-0.3 7,-0.2 -0.957 37.4 -83.2-147.3 160.8 31.3 -10.7 23.4 52 1567 A F E -C 33 0B 39 5,-1.5 5,-0.2 -2,-0.3 -19,-0.2 -0.297 49.6-107.6 -65.9 154.7 29.6 -7.6 24.8 53 1568 A G S > S+ 0 0 9 -21,-1.6 3,-0.7 2,-0.2 -22,-0.1 0.932 97.2 5.3 -52.6 -94.2 30.0 -6.8 28.6 54 1569 A Q T 3 S+ 0 0 188 1,-0.2 -1,-0.2 2,-0.1 2,-0.1 0.772 133.3 51.5 -66.7 -26.5 27.0 -7.4 30.8 55 1570 A T T 3 S- 0 0 93 2,-0.1 -3,-0.2 -4,-0.0 -1,-0.2 -0.297 92.9-131.1-116.2 48.4 24.9 -8.8 27.9 56 1571 A R < + 0 0 155 -3,-0.7 2,-0.6 -4,-0.2 -3,-0.1 0.523 38.4 171.5 5.8 75.4 27.0 -11.6 26.3 57 1572 A I - 0 0 55 -5,-0.2 -5,-1.5 24,-0.0 2,-0.5 -0.938 35.4-124.0-110.4 113.5 26.6 -10.5 22.6 58 1573 A S E +D 51 0B 14 -2,-0.6 23,-2.8 -7,-0.2 33,-0.3 -0.377 28.8 178.8 -59.0 106.5 28.8 -12.5 20.2 59 1574 A V E S- 0 0 0 -9,-2.1 62,-0.2 -2,-0.5 21,-0.2 0.262 73.8 -19.9 -90.9 10.6 30.9 -9.9 18.3 60 1575 A G E -D 50 0B 0 -10,-0.5 -10,-1.3 32,-0.2 -11,-1.1 -0.500 66.5-107.0 152.9 139.4 32.6 -12.9 16.5 61 1576 A K B -E 78 0C 111 17,-3.6 17,-0.7 -13,-0.3 -13,-0.3 -0.708 48.3-106.3 -84.4 134.1 33.2 -16.6 16.8 62 1577 A A + 0 0 29 -2,-0.4 2,-0.3 15,-0.2 -22,-0.1 -0.132 47.9 153.1 -62.0 150.3 36.8 -17.6 17.6 63 1578 A N - 0 0 24 -24,-0.2 -25,-0.3 2,-0.0 -24,-0.2 -0.950 50.2-120.4-160.7 179.2 39.3 -19.0 15.2 64 1579 A K + 0 0 125 -2,-0.3 2,-1.3 -26,-0.1 -62,-0.3 0.353 64.6 128.8-107.7 0.5 43.0 -19.4 14.3 65 1580 A R + 0 0 174 11,-0.2 11,-0.7 -64,-0.1 2,-0.7 -0.415 36.2 178.4 -64.4 90.5 42.7 -17.8 10.9 66 1581 A L E -F 75 0D 18 -2,-1.3 2,-0.3 -64,-0.3 9,-0.2 -0.845 9.7-163.6-107.9 102.8 45.6 -15.2 11.2 67 1582 A R E -F 74 0D 189 7,-2.3 7,-3.5 -2,-0.7 2,-0.7 -0.615 13.8-138.9 -84.7 140.7 46.2 -13.0 8.2 68 1583 A Y E +F 73 0D 49 -2,-0.3 2,-0.5 5,-0.2 5,-0.2 -0.900 25.8 176.3 -96.6 116.1 49.4 -11.0 7.7 69 1584 A V E > -F 72 0D 57 3,-3.0 3,-1.3 -2,-0.7 -2,-0.0 -0.907 62.4 -42.9-126.2 103.8 48.6 -7.6 6.3 70 1585 A D T 3 S- 0 0 45 -2,-0.5 -1,-0.1 1,-0.3 3,-0.1 0.918 121.9 -33.7 41.2 81.2 51.6 -5.1 5.9 71 1586 A Q T 3 S+ 0 0 72 1,-0.1 2,-0.5 27,-0.1 -1,-0.3 0.365 121.1 107.5 64.5 -3.8 53.6 -5.6 9.1 72 1587 A V E < -F 69 0D 5 -3,-1.3 -3,-3.0 26,-0.1 2,-0.7 -0.910 65.0-141.8-114.0 127.0 50.4 -6.3 11.0 73 1588 A L E -FG 68 97D 0 24,-1.6 24,-3.4 -2,-0.5 2,-0.5 -0.764 29.7-167.3 -81.7 116.1 49.1 -9.6 12.3 74 1589 A Q E -FG 67 96D 46 -7,-3.5 -7,-2.3 -2,-0.7 2,-0.3 -0.922 13.5-171.3-116.4 128.7 45.3 -9.6 11.8 75 1590 A L E -FG 66 95D 0 20,-3.8 20,-0.6 -2,-0.5 2,-0.4 -0.841 8.0-156.3-106.2 152.2 42.7 -11.9 13.2 76 1591 A V E - G 0 94D 49 -11,-0.7 2,-0.7 -2,-0.3 18,-0.2 -0.988 3.4-158.6-130.3 121.5 39.0 -11.9 12.1 77 1592 A Y E - G 0 93D 0 16,-2.4 16,-1.8 -2,-0.4 3,-0.2 -0.887 26.7-170.8-100.9 108.3 36.2 -13.2 14.3 78 1593 A K B +E 61 0C 86 -2,-0.7 -17,-3.6 -17,-0.7 13,-0.1 -0.275 47.6 30.9 -96.5 173.7 33.4 -14.1 12.0 79 1594 A D S S+ 0 0 96 -19,-0.2 -19,-0.2 11,-0.1 -1,-0.2 0.830 71.8 163.0 47.4 51.0 29.7 -15.1 12.3 80 1595 A G - 0 0 11 11,-2.3 -21,-0.2 -3,-0.2 3,-0.1 0.017 47.1 -52.6 -77.1-166.4 28.8 -13.3 15.5 81 1596 A S S S- 0 0 29 -23,-2.8 10,-1.7 9,-0.2 -1,-0.2 -0.223 79.0 -66.2 -67.1 159.2 25.3 -12.5 16.7 82 1597 A P B -J 90 0E 105 0, 0.0 8,-0.2 0, 0.0 -1,-0.2 -0.063 52.1-131.1 -42.3 143.8 22.7 -10.7 14.5 83 1598 A c - 0 0 9 6,-1.8 6,-0.3 3,-0.5 3,-0.2 -0.874 11.1-126.6-107.2 136.8 23.4 -7.1 13.5 84 1599 A P S S+ 0 0 114 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 0.658 100.8 69.1 -49.9 -22.3 20.9 -4.2 13.9 85 1600 A S S S- 0 0 58 1,-0.2 2,-0.3 31,-0.2 33,-0.1 0.994 111.9 -15.4 -66.4 -68.7 21.5 -3.3 10.2 86 1601 A K S > S- 0 0 145 -3,-0.2 3,-1.1 3,-0.1 -3,-0.5 -0.920 79.3 -79.2-137.5 164.3 19.9 -6.2 8.3 87 1602 A S T 3 S+ 0 0 117 -2,-0.3 3,-0.1 1,-0.2 -1,-0.0 -0.284 110.4 8.3 -61.5 141.5 18.7 -9.7 8.8 88 1603 A G T 3 S+ 0 0 76 1,-0.2 2,-0.4 -5,-0.0 -1,-0.2 0.322 89.3 137.6 71.5 -9.3 21.2 -12.5 8.9 89 1604 A L < - 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A 0 429K 1 64,-2.0 64,-2.2 -2,-0.4 2,-0.3 -0.785 20.4-175.7 -99.2 153.9 71.0 21.7 30.0 366 1888 A V E +Z 346 0K 21 -20,-0.7 -20,-2.6 -2,-0.3 -17,-0.2 -0.925 42.6 41.7-148.5 160.7 68.1 20.9 27.7 367 1889 A N + 0 0 15 59,-0.3 61,-0.2 -2,-0.3 -1,-0.1 0.857 65.4 145.1 70.0 42.2 66.2 18.2 25.7 368 1890 A G - 0 0 7 59,-2.4 2,-0.3 1,-0.3 -24,-0.2 0.592 59.0 -32.2 -76.6-129.7 66.2 15.3 28.2 369 1891 A D S S- 0 0 71 -26,-2.6 58,-3.0 1,-0.1 -1,-0.3 -0.671 80.5 -81.0 -92.7 153.4 63.3 12.9 28.5 370 1892 A R B -D 426 0L 67 56,-0.3 56,-0.3 -2,-0.3 -1,-0.1 -0.100 51.1-107.1 -47.4 145.9 59.7 13.9 27.9 371 1893 A k - 0 0 9 54,-2.4 52,-0.4 1,-0.1 82,-0.2 -0.387 44.2 -93.5 -72.6 155.9 58.0 15.7 30.8 372 1894 A P - 0 0 38 0, 0.0 -1,-0.1 0, 0.0 2,-0.1 -0.339 41.3-106.2 -74.7 157.6 55.3 13.7 32.7 373 1895 A P - 0 0 16 0, 0.0 8,-1.2 0, 0.0 2,-0.3 -0.355 26.9-157.5 -74.9 157.3 51.6 13.8 31.9 374 1896 A E E -EF 380 421M 21 47,-1.8 47,-2.9 6,-0.2 2,-0.1 -0.736 30.8 -88.2-119.0 176.2 48.9 15.6 33.9 375 1897 A T E > - F 0 420M 3 4,-1.5 3,-2.3 -2,-0.3 45,-0.2 -0.376 40.2-102.8 -78.4 165.6 45.2 14.9 34.0 376 1898 A D T 3 S+ 0 0 95 43,-1.8 -1,-0.1 1,-0.3 44,-0.1 0.877 127.2 51.4 -51.5 -42.0 42.7 16.5 31.6 377 1899 A D T 3 S- 0 0 161 42,-0.2 -1,-0.3 2,-0.1 -2,-0.0 0.284 123.1-109.0 -84.1 9.8 41.7 18.8 34.4 378 1900 A G S < S+ 0 0 32 -3,-2.3 -2,-0.1 1,-0.2 -1,-0.0 0.658 71.3 137.3 78.0 19.5 45.4 19.7 35.0 379 1901 A V - 0 0 73 1,-0.0 -4,-1.5 38,-0.0 -1,-0.2 -0.887 58.2-109.8 -99.3 123.9 46.2 17.9 38.3 380 1902 A P B -E 374 0M 68 0, 0.0 -6,-0.2 0, 0.0 2,-0.1 -0.107 25.2-116.4 -61.7 146.0 49.6 16.1 38.1 381 1903 A l - 0 0 21 -8,-1.2 2,-0.6 -6,-0.0 26,-0.2 -0.405 21.3-134.0 -70.7 152.3 50.0 12.4 38.0 382 1904 A V - 0 0 47 24,-1.9 24,-0.3 26,-0.3 26,-0.2 -0.960 23.6-133.6-112.7 116.0 51.8 10.6 40.8 383 1905 A F S S+ 0 0 65 -2,-0.6 10,-0.1 1,-0.1 2,-0.1 -0.952 83.1 30.2-112.4 134.6 54.4 8.0 39.8 384 1906 A P S S+ 0 0 61 0, 0.0 2,-0.3 0, 0.0 9,-0.2 0.660 80.9 172.9 -81.9 162.4 54.6 5.4 40.9 385 1907 A F E -G 392 0N 0 7,-2.1 7,-2.9 -2,-0.1 2,-0.5 -0.970 28.4-126.2-130.5 150.4 51.0 4.5 41.9 386 1908 A I E +Gh 391 410N 65 23,-1.6 25,-1.5 -2,-0.3 26,-1.2 -0.817 32.2 164.7 -97.1 128.9 49.3 1.3 43.1 387 1909 A F E > S-G 390 0N 9 3,-2.3 3,-1.5 -2,-0.5 -2,-0.0 -0.971 74.0 -6.4-144.5 127.8 46.3 -0.0 41.3 388 1910 A N T 3 S- 0 0 110 -2,-0.3 3,-0.1 1,-0.3 -1,-0.0 0.864 129.6 -59.5 48.3 41.2 45.0 -3.5 41.8 389 1911 A G T 3 S+ 0 0 54 1,-0.2 2,-0.4 0, 0.0 -1,-0.3 0.652 115.9 108.8 68.2 18.2 48.0 -4.2 44.0 390 1912 A K E < -G 387 0N 129 -3,-1.5 -3,-2.3 -5,-0.0 2,-0.4 -0.973 67.7-124.2-125.5 143.6 50.5 -3.5 41.3 391 1913 A S E -G 386 0N 75 -2,-0.4 2,-0.4 -5,-0.2 -5,-0.2 -0.720 27.2-166.8 -88.2 127.9 52.9 -0.5 41.0 392 1914 A Y E -G 385 0N 44 -7,-2.9 -7,-2.1 -2,-0.4 4,-0.1 -0.918 19.5-172.9-119.3 146.1 52.7 1.5 37.7 393 1915 A E S S+ 0 0 103 -2,-0.4 2,-0.3 -9,-0.2 -1,-0.1 0.320 70.8 35.1-115.0 2.9 55.1 4.2 36.4 394 1916 A E S S- 0 0 69 -9,-0.1 2,-0.1 10,-0.1 -9,-0.1 -0.909 99.2 -66.0-151.4 166.6 53.1 5.4 33.4 395 1917 A m - 0 0 5 -2,-0.3 2,-0.2 10,-0.1 10,-0.2 -0.451 57.9-158.0 -63.8 137.3 49.5 6.1 32.1 396 1918 A I B -I 404 0O 0 8,-2.6 8,-2.6 -2,-0.1 2,-0.4 -0.697 23.0-141.3-116.6 161.8 47.6 2.9 31.9 397 1919 A I + 0 0 5 -292,-0.4 2,-0.4 -2,-0.2 6,-0.1 -0.853 49.6 132.3-122.0 93.8 44.5 1.5 30.0 398 1920 A E S S- 0 0 47 -2,-0.4 -2,-0.1 4,-0.2 3,-0.1 -0.984 77.6 -7.2-145.0 130.2 42.8 -0.8 32.5 399 1921 A S S S+ 0 0 69 -2,-0.4 2,-0.3 1,-0.1 -374,-0.1 0.671 122.9 79.6 57.8 19.4 39.0 -0.8 33.3 400 1922 A R S S- 0 0 40 1,-0.1 -374,-0.3 -374,-0.0 -1,-0.1 -0.972 77.6-129.6-153.4 160.6 38.8 2.3 31.1 401 1923 A A S S+ 0 0 31 -2,-0.3 2,-0.3 -373,-0.2 -375,-0.1 0.837 88.3 39.9 -84.8 -36.5 38.7 3.4 27.4 402 1924 A K S S- 0 0 39 1,-0.1 -4,-0.2 -4,-0.1 -6,-0.1 -0.797 100.0 -79.0-117.5 155.9 41.4 6.0 27.3 403 1925 A L + 0 0 18 -2,-0.3 17,-2.1 -248,-0.1 2,-0.3 -0.266 58.4 174.8 -52.9 130.0 44.9 6.3 28.9 404 1926 A W E -IJ 396 419O 0 -8,-2.6 -8,-2.6 15,-0.3 2,-0.3 -0.930 18.3-160.2-139.6 161.1 44.6 7.4 32.5 405 1927 A l E - J 0 418O 0 13,-1.8 13,-1.6 -2,-0.3 2,-0.2 -0.929 23.1-112.4-135.9 161.5 46.8 8.0 35.6 406 1928 A S E - J 0 417O 0 -2,-0.3 -24,-1.9 -24,-0.3 11,-0.3 -0.581 10.5-151.7 -87.8 158.7 46.3 8.2 39.4 407 1929 A T S S+ 0 0 22 9,-1.7 2,-0.3 -26,-0.2 10,-0.2 0.192 79.7 53.9-115.9 11.3 46.9 11.5 41.3 408 1930 A T S S- 0 0 26 8,-0.5 -26,-0.3 -26,-0.2 3,-0.3 -0.916 91.1-111.3-133.4 163.7 47.9 9.8 44.5 409 1931 A A S S+ 0 0 52 -2,-0.3 -23,-1.6 1,-0.2 2,-0.4 0.721 111.2 40.3 -65.8 -21.6 50.5 7.2 45.3 410 1932 A D B > +h 386 0N 39 -25,-0.2 4,-2.2 1,-0.2 3,-0.4 -0.832 58.5 175.4-136.1 94.6 47.8 4.7 46.1 411 1933 A Y H > S+ 0 0 29 -25,-1.5 4,-3.7 -2,-0.4 -24,-0.2 0.963 83.5 61.1 -59.5 -55.3 44.8 4.6 43.8 412 1934 A D H 4 S+ 0 0 57 -26,-1.2 -1,-0.2 1,-0.2 -25,-0.1 0.802 115.2 36.6 -37.1 -39.4 43.3 1.5 45.5 413 1935 A R H 4 S+ 0 0 153 -3,-0.4 -1,-0.2 -27,-0.2 -2,-0.2 0.859 131.7 24.4 -85.3 -40.4 43.2 3.7 48.7 414 1936 A D H < S- 0 0 56 -4,-2.2 -3,-0.2 2,-0.1 -2,-0.2 0.652 77.6-151.8-110.2 -21.9 42.3 7.1 47.4 415 1937 A H < + 0 0 115 -4,-3.7 2,-0.4 -5,-0.3 -4,-0.1 0.776 45.0 139.9 51.8 35.1 40.5 6.5 44.1 416 1938 A E + 0 0 117 -6,-0.1 -9,-1.7 -5,-0.1 -8,-0.5 -0.925 18.9 127.2-111.6 139.1 41.5 9.8 42.6 417 1939 A W E -J 406 0O 88 -2,-0.4 2,-0.3 -11,-0.3 -11,-0.2 -0.951 31.5-159.7-173.0 169.8 42.5 9.9 38.9 418 1940 A G E -J 405 0O 12 -13,-1.6 -13,-1.8 -2,-0.3 3,-0.1 -0.941 40.0 -82.6-167.3 152.8 41.9 11.6 35.6 419 1941 A F E -J 404 0O 61 -2,-0.3 -43,-1.8 -15,-0.2 -15,-0.3 -0.376 56.1-109.6 -59.9 136.3 42.4 10.8 31.9 420 1942 A m E -F 375 0M 12 -17,-2.1 2,-0.4 -45,-0.2 -45,-0.2 -0.461 27.0-168.3 -70.0 134.9 46.0 11.6 30.9 421 1943 A R E -F 374 0M 98 -47,-2.9 -47,-1.8 -2,-0.2 2,-0.1 -0.999 29.4-131.6-112.9 126.9 46.8 14.6 28.6 422 1944 A H - 0 0 59 -2,-0.4 2,-0.0 -49,-0.2 -47,-0.0 -0.408 9.5-119.6 -86.6 154.3 50.4 14.2 27.5 423 1945 A S - 0 0 30 -52,-0.4 -1,-0.1 -2,-0.1 -53,-0.1 -0.253 13.1-166.5 -79.2 170.1 53.2 16.7 27.6 424 1946 A N + 0 0 113 2,-0.1 -174,-0.4 -2,-0.0 2,-0.3 0.453 64.0 90.8-131.8 -20.7 55.1 17.9 24.5 425 1947 A S - 0 0 55 -176,-0.1 -54,-2.4 -175,-0.1 2,-0.3 -0.611 68.9-142.5 -72.0 135.9 58.0 19.6 26.3 426 1948 A Y B -D 370 0L 7 -178,-0.5 -59,-0.3 -2,-0.3 -56,-0.3 -0.684 41.7 -75.9 -92.1 159.9 61.0 17.4 27.0 427 1949 A R - 0 0 41 -58,-3.0 -59,-2.4 -84,-0.3 2,-0.3 -0.287 47.0-171.7 -74.3 136.5 62.8 18.0 30.3 428 1950 A T E - b 0 454K 30 25,-2.2 27,-1.1 -62,-0.2 2,-0.3 -0.797 3.2-176.0-113.5 157.8 65.1 21.0 31.1 429 1951 A S E -Ab 365 455K 2 -64,-2.2 -64,-2.0 -2,-0.3 2,-0.3 -0.984 0.7-177.2-146.2 159.6 67.4 21.8 34.0 430 1952 A S E -Ab 364 456K 17 25,-2.8 27,-2.1 -2,-0.3 2,-0.5 -0.984 17.7-147.5-153.4 144.4 69.6 24.7 35.0 431 1953 A I E -Ab 363 457K 0 -68,-1.7 -68,-2.5 -2,-0.3 2,-0.6 -0.956 13.5-153.8-105.4 132.0 72.0 25.7 37.7 432 1954 A I E -Ab 362 458K 8 25,-2.9 27,-2.2 -2,-0.5 2,-0.7 -0.951 13.7-148.0-101.8 118.3 72.2 29.3 38.7 433 1955 A F E -Ab 361 459K 0 -72,-4.0 -72,-2.1 -2,-0.6 2,-0.3 -0.793 15.5-171.3 -91.3 115.9 75.6 30.1 40.1 434 1956 A K E - b 0 460K 83 25,-2.2 27,-1.3 -2,-0.7 2,-0.4 -0.723 27.3-101.9-104.5 156.8 75.7 32.8 42.8 435 1957 A n E + b 0 461K 44 -2,-0.3 2,-0.3 25,-0.2 27,-0.2 -0.641 43.7 156.5 -89.2 132.4 78.8 34.4 44.3 436 1958 A D > - 0 0 49 25,-2.2 3,-1.1 -2,-0.4 28,-0.1 -0.829 28.3-152.7-153.2 111.0 80.2 33.5 47.7 437 1959 A E T 3 S+ 0 0 49 1,-0.3 2,-0.2 -2,-0.3 25,-0.1 0.810 91.1 49.1 -57.0 -40.3 84.0 34.1 48.5 438 1960 A D T 3 S+ 0 0 136 1,-0.1 2,-0.3 23,-0.1 -1,-0.3 -0.236 83.1 93.0-103.1 46.3 84.4 31.3 51.2 439 1961 A E < - 0 0 78 -3,-1.1 23,-1.7 1,-0.2 24,-0.4 -0.784 57.2-171.4-125.0 84.6 82.8 28.5 49.3 440 1962 A D S S- 0 0 133 -2,-0.3 22,-0.6 1,-0.3 23,-0.4 0.909 85.0 -9.1 -41.1 -67.6 86.0 27.1 47.7 441 1963 A I S S- 0 0 60 20,-0.1 -1,-0.3 21,-0.1 20,-0.1 -0.981 94.4-151.4-124.8 130.2 83.9 24.8 45.6 442 1964 A G - 0 0 7 -2,-0.4 19,-0.1 -3,-0.3 -1,-0.1 0.418 9.0-115.8 -80.2-146.1 80.4 24.9 46.8 443 1965 A R - 0 0 138 17,-0.2 17,-0.4 15,-0.1 15,-0.1 -0.832 26.8-123.7-160.1 123.7 77.5 22.4 46.8 444 1966 A P - 0 0 0 0, 0.0 2,-0.3 0, 0.0 15,-0.2 -0.295 22.5-165.3 -71.0 153.2 74.3 22.9 44.8 445 1967 A Q E -C 458 0K 105 13,-2.0 13,-2.1 -140,-0.1 2,-0.4 -0.900 33.0 -92.9-129.3 162.6 70.8 22.9 46.4 446 1968 A V E +C 457 0K 12 -2,-0.3 11,-0.3 11,-0.2 3,-0.1 -0.647 41.6 171.4 -79.4 127.5 67.4 22.5 44.8 447 1969 A F E - 0 0 115 9,-3.1 2,-0.3 -2,-0.4 10,-0.2 0.817 61.7 -5.4-103.6 -43.5 65.8 25.9 44.1 448 1970 A S E -C 456 0K 37 8,-1.9 8,-2.6 2,-0.0 -1,-0.4 -0.985 49.9-171.3-155.3 144.7 62.7 25.2 42.0 449 1971 A E E -C 455 0K 46 -2,-0.3 2,-0.5 6,-0.2 6,-0.2 -0.995 9.9-164.4-137.2 132.8 61.0 22.2 40.4 450 1972 A V E >> -C 454 0K 63 4,-1.4 3,-2.8 -2,-0.4 4,-1.1 -0.966 66.3 -36.7-125.9 114.1 58.0 22.6 38.1 451 1973 A R T 34 S- 0 0 173 -2,-0.5 -1,-0.1 1,-0.3 0, 0.0 0.735 103.7 -73.2 51.8 32.3 55.7 19.7 37.1 452 1974 A G T 34 S+ 0 0 31 2,-0.2 -1,-0.3 -81,-0.1 3,-0.1 0.801 123.2 97.9 51.4 33.8 58.6 17.3 37.1 453 1975 A k T <4 S+ 0 0 20 -3,-2.8 -25,-2.2 1,-0.3 2,-0.3 0.589 81.1 28.9-124.7 -25.5 59.7 19.0 33.8 454 1976 A D E < -bC 428 450K 38 -4,-1.1 -4,-1.4 -27,-0.2 2,-0.4 -0.993 57.5-166.3-134.1 148.1 62.3 21.5 34.9 455 1977 A V E -bC 429 449K 0 -27,-1.1 -25,-2.8 -2,-0.3 2,-0.4 -0.995 3.4-173.0-130.3 133.2 64.9 21.7 37.8 456 1978 A T E -bC 430 448K 17 -8,-2.6 -9,-3.1 -2,-0.4 -8,-1.9 -0.990 6.2-167.4-122.1 130.0 66.8 24.7 38.9 457 1979 A F E -bC 431 446K 0 -27,-2.1 -25,-2.9 -2,-0.4 2,-0.5 -0.824 15.3-139.1-109.0 150.6 69.6 24.5 41.5 458 1980 A E E -bC 432 445K 58 -13,-2.1 -13,-2.0 -2,-0.3 2,-0.5 -0.967 21.6-174.0-106.2 127.9 71.3 27.3 43.3 459 1981 A W E -b 433 0K 0 -27,-2.2 -25,-2.2 -2,-0.5 2,-0.8 -0.976 10.9-161.0-125.8 117.5 75.0 26.9 43.7 460 1982 A K E +b 434 0K 92 -2,-0.5 -17,-0.2 -17,-0.4 2,-0.2 -0.837 28.1 156.3 -99.6 99.6 77.1 29.3 45.7 461 1983 A T E -b 435 0K 0 -27,-1.3 -25,-2.2 -2,-0.8 3,-0.2 -0.677 52.3-128.6-111.4 170.9 80.8 29.0 44.7 462 1984 A K S > S+ 0 0 87 -23,-1.7 3,-1.1 -22,-0.6 -22,-0.1 0.755 98.8 83.2 -79.5 -30.3 83.9 31.2 44.9 463 1985 A V T 3 S+ 0 0 22 -23,-0.4 -169,-0.4 -24,-0.4 -1,-0.1 0.691 87.3 51.3 -45.6 -31.1 84.4 30.4 41.2 464 1986 A V T 3 S+ 0 0 3 -30,-0.3 -1,-0.3 -3,-0.2 -29,-0.1 -0.225 106.0 51.8-108.2 46.5 81.9 33.1 40.1 465 1987 A n < + 0 0 8 -3,-1.1 -2,-0.1 -29,-0.1 -1,-0.1 0.704 64.5 109.9-127.0 -53.3 83.1 36.2 42.0 466 1988 A P + 0 0 71 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 -0.479 26.3 105.9-100.4 75.5 86.6 37.3 41.9 467 1989 A P + 0 0 11 0, 0.0 72,-0.1 0, 0.0 3,-0.1 -0.843 23.9 143.6-112.8 98.8 88.0 40.4 40.2 468 1990 A K S S+ 0 0 64 -2,-0.4 41,-1.5 1,-0.1 2,-0.3 0.335 77.0 48.0 -95.3 1.2 88.7 42.8 43.1 469 1991 A K B S-K 508 0P 129 39,-0.2 2,-0.3 -3,-0.1 39,-0.2 -0.991 74.9-178.8-143.6 137.6 91.7 43.8 41.0 470 1992 A L - 0 0 50 37,-2.0 2,-0.2 -2,-0.3 69,-0.0 -0.922 29.9 -93.3-142.8 162.0 91.7 44.7 37.3 471 1993 A E - 0 0 133 -2,-0.3 36,-0.1 1,-0.1 37,-0.0 -0.543 18.8-169.5 -78.3 141.5 94.0 45.7 34.4 472 1994 A o + 0 0 4 -2,-0.2 11,-2.2 34,-0.1 2,-0.6 -0.069 62.3 99.3-115.4 29.0 94.6 49.3 33.6 473 1995 A K E +L 482 0Q 120 9,-0.2 2,-0.3 10,-0.1 9,-0.2 -0.947 51.2 151.1-115.9 103.9 96.3 48.6 30.3 474 1996 A F E -L 481 0Q 26 7,-1.4 7,-1.6 -2,-0.6 2,-0.4 -0.854 34.3-135.1-130.3 167.8 93.8 49.0 27.5 475 1997 A V E +L 480 0Q 96 -2,-0.3 2,-0.4 5,-0.2 5,-0.2 -0.987 15.0 179.7-130.9 134.1 93.7 49.9 23.8 476 1998 A Q S S- 0 0 74 3,-1.9 3,-0.2 -2,-0.4 68,-0.0 -0.982 76.9 -20.9-132.7 122.1 91.4 52.2 21.7 477 1999 A K S S- 0 0 188 -2,-0.4 3,-0.1 1,-0.2 -1,-0.1 0.854 129.5 -47.6 48.9 45.2 91.9 52.7 18.0 478 2000 A H S S+ 0 0 187 1,-0.2 2,-0.3 0, 0.0 -1,-0.2 0.894 112.7 115.4 61.8 46.9 95.5 51.5 18.2 479 2001 A K - 0 0 126 -3,-0.2 -3,-1.9 2,-0.0 2,-0.5 -0.962 51.6-149.4-141.5 127.4 96.6 53.6 21.2 480 2002 A T E -L 475 0Q 77 -2,-0.3 125,-0.5 -5,-0.2 2,-0.4 -0.859 11.4-170.7-107.9 121.0 97.7 52.1 24.5 481 2003 A Y E -L 474 0Q 26 -7,-1.6 -7,-1.4 -2,-0.5 2,-0.6 -0.870 9.4-155.9-112.4 140.2 97.1 53.8 27.9 482 2004 A D E > +L 473 0Q 60 119,-0.5 3,-0.7 -2,-0.4 -9,-0.2 -0.833 18.1 169.6-123.3 93.9 98.5 52.7 31.2 483 2005 A L G >> + 0 0 0 -11,-2.2 3,-2.2 -2,-0.6 4,-0.7 0.428 48.7 109.4 -83.2 1.1 96.6 53.9 34.3 484 2006 A R G 34 + 0 0 162 -12,-0.4 -1,-0.2 1,-0.3 3,-0.2 0.694 66.8 71.9 -53.4 -20.4 98.5 51.7 36.7 485 2007 A L G <4 S+ 0 0 87 -3,-0.7 -1,-0.3 1,-0.2 -2,-0.1 0.889 102.6 38.9 -59.6 -41.7 100.1 54.9 38.0 486 2008 A L T <4 S+ 0 0 1 -3,-2.2 2,-1.0 2,-0.1 20,-0.7 0.527 90.3 98.9 -91.5 -9.0 96.8 56.0 39.7 487 2009 A S < - 0 0 17 -4,-0.7 2,-0.5 -3,-0.2 20,-0.1 -0.707 65.8-153.5 -83.3 101.0 95.7 52.5 40.9 488 2010 A S - 0 0 26 -2,-1.0 3,-0.2 1,-0.1 23,-0.1 -0.649 19.6-167.8 -85.6 125.5 96.8 52.5 44.6 489 2011 A L S S+ 0 0 122 -2,-0.5 2,-0.3 1,-0.2 -1,-0.1 0.444 85.0 50.9 -81.8 -0.6 97.5 49.1 46.2 490 2012 A T S S- 0 0 129 21,-0.1 2,-0.4 22,-0.0 -1,-0.2 -0.778 120.7 -38.3-147.9 91.0 97.5 50.9 49.5 491 2013 A G S S- 0 0 19 -2,-0.3 20,-2.0 -3,-0.2 2,-0.3 -0.763 73.6-100.3 94.4-140.3 94.6 53.2 50.5 492 2014 A S - 0 0 43 -2,-0.4 2,-0.3 18,-0.2 13,-0.2 -0.959 26.8 -85.6-167.5 178.8 92.8 55.5 48.0 493 2015 A W E -M 504 0R 45 11,-2.1 11,-2.7 -2,-0.3 2,-0.4 -0.788 37.9-161.7 -99.3 147.1 92.4 59.1 46.7 494 2016 A S E -M 503 0R 54 -2,-0.3 2,-0.4 9,-0.2 9,-0.2 -0.981 12.7-176.8-137.1 125.2 90.1 61.6 48.4 495 2017 A L E -M 502 0R 15 7,-1.6 7,-2.9 -2,-0.4 2,-0.6 -0.923 18.3-145.3-107.9 143.2 88.6 64.8 47.2 496 2018 A V E +M 501 0R 100 -2,-0.4 2,-0.5 5,-0.2 5,-0.2 -0.951 20.5 179.2-106.7 114.8 86.5 67.0 49.5 497 2019 A H E > -M 500 0R 67 3,-2.8 3,-1.6 -2,-0.6 -2,-0.0 -0.968 69.7 -22.1-118.5 116.4 83.7 68.7 47.7 498 2020 A N T 3 S- 0 0 136 -2,-0.5 30,-0.2 1,-0.3 -1,-0.1 0.892 123.2 -53.9 53.5 48.6 81.3 70.9 49.7 499 2021 A G T 3 S+ 0 0 41 1,-0.2 2,-0.6 28,-0.1 -1,-0.3 0.202 117.3 115.8 75.3 -17.7 82.1 69.2 53.0 500 2022 A V E < -M 497 0R 19 -3,-1.6 -3,-2.8 27,-0.1 2,-0.3 -0.759 61.2-142.4 -87.2 119.2 81.2 65.9 51.4 501 2023 A S E -MN 496 526R 25 25,-2.0 25,-2.9 -2,-0.6 2,-0.4 -0.605 12.5-161.5 -81.0 140.5 84.2 63.6 51.2 502 2024 A Y E -MN 495 525R 10 -7,-2.9 -7,-1.6 -2,-0.3 2,-0.5 -0.988 2.6-161.2-122.6 133.4 84.7 61.4 48.1 503 2025 A Y E +MN 494 524R 45 21,-1.6 21,-3.9 -2,-0.4 2,-0.4 -0.970 16.7 173.2-117.4 129.7 87.0 58.3 48.0 504 2026 A I E +MN 493 523R 7 -11,-2.7 -11,-2.1 -2,-0.5 2,-0.4 -0.998 11.5 174.3-144.2 126.5 88.1 57.0 44.6 505 2027 A N > - 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