==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=5-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE 24-SEP-07 2VCJ . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR P.A.BROUGH,W.AHERNE,X.BARRIL,J.BORGOGNONI,K.BOXAL, . 208 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10449.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 157 75.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 40 19.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 21 10.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 31 14.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 55 26.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 0 0 1 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 2 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A E 0 0 125 0, 0.0 158,-0.3 0, 0.0 2,-0.1 0.000 360.0 360.0 360.0 -77.3 37.6 27.5 38.6 2 17 A V - 0 0 89 156,-0.1 2,-0.4 154,-0.1 156,-0.2 -0.348 360.0-173.1 -80.1 134.5 40.0 26.6 35.7 3 18 A E E -A 157 0A 78 154,-0.7 154,-1.7 -2,-0.1 2,-0.5 -0.963 14.1-149.7-113.8 145.2 42.8 24.0 35.5 4 19 A T E +A 156 0A 103 -2,-0.4 2,-0.2 152,-0.2 152,-0.2 -0.939 17.6 179.1-120.3 114.4 45.1 23.8 32.5 5 20 A F E -A 155 0A 58 150,-1.8 150,-1.4 -2,-0.5 2,-0.4 -0.694 26.0-117.8-109.8 164.8 46.7 20.5 31.4 6 21 A A E -A 154 0A 77 148,-0.2 148,-0.3 -2,-0.2 3,-0.1 -0.849 27.6-116.7 -99.0 136.1 49.0 19.6 28.5 7 22 A F - 0 0 14 146,-2.3 2,-0.1 -2,-0.4 -1,-0.0 -0.421 43.6 -96.3 -58.5 139.9 47.9 17.1 25.8 8 23 A Q >> - 0 0 75 1,-0.1 4,-2.0 -2,-0.1 3,-0.6 -0.438 42.4-109.6 -51.6 140.6 50.2 14.1 25.8 9 24 A A H 3> S+ 0 0 67 1,-0.2 4,-1.3 2,-0.2 -1,-0.1 0.791 116.2 51.0 -51.4 -39.5 52.8 14.7 23.2 10 25 A E H 3> S+ 0 0 59 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.877 109.2 50.1 -69.4 -39.4 51.4 12.1 20.7 11 26 A I H <> S+ 0 0 0 -3,-0.6 4,-2.8 2,-0.2 5,-0.2 0.872 106.4 56.7 -60.6 -39.3 47.8 13.5 20.9 12 27 A A H X S+ 0 0 31 -4,-2.0 4,-1.8 1,-0.2 -1,-0.2 0.882 108.1 47.4 -63.1 -34.4 49.2 17.0 20.2 13 28 A Q H X S+ 0 0 100 -4,-1.3 4,-3.2 2,-0.2 -1,-0.2 0.895 108.9 55.0 -69.7 -41.6 50.8 15.6 17.0 14 29 A L H X S+ 0 0 0 -4,-2.1 4,-2.2 2,-0.2 -2,-0.2 0.972 110.9 44.0 -52.3 -58.8 47.5 13.9 16.1 15 30 A M H X S+ 0 0 3 -4,-2.8 4,-2.1 1,-0.2 -1,-0.2 0.834 113.2 51.3 -55.5 -40.5 45.6 17.3 16.4 16 31 A S H X S+ 0 0 60 -4,-1.8 4,-1.9 2,-0.2 5,-0.2 0.924 109.6 49.7 -65.5 -45.3 48.3 19.1 14.5 17 32 A L H X S+ 0 0 39 -4,-3.2 4,-2.1 1,-0.2 -2,-0.2 0.884 112.7 49.1 -56.6 -41.7 48.1 16.5 11.7 18 33 A I H < S+ 0 0 3 -4,-2.2 -2,-0.2 1,-0.2 -1,-0.2 0.796 113.9 44.5 -69.0 -34.2 44.3 17.0 11.7 19 34 A I H < S+ 0 0 73 -4,-2.1 -1,-0.2 -5,-0.2 -2,-0.2 0.787 124.6 33.1 -76.7 -29.3 44.6 20.8 11.5 20 35 A N H < S+ 0 0 114 -4,-1.9 -2,-0.2 -5,-0.2 -3,-0.2 0.935 86.8 96.8-101.5 -54.6 47.3 20.8 8.9 21 36 A T S < S- 0 0 60 -4,-2.1 2,-0.6 -5,-0.2 -4,-0.0 -0.080 78.8-118.3 -39.7 125.1 47.0 17.9 6.4 22 37 A F + 0 0 186 2,-0.0 2,-0.3 0, 0.0 -1,-0.1 -0.661 54.1 152.4 -67.1 122.6 45.1 18.9 3.3 23 38 A Y - 0 0 29 -2,-0.6 3,-0.1 -3,-0.1 89,-0.0 -0.865 28.9-170.0-163.5 116.9 42.0 16.7 3.4 24 39 A S + 0 0 87 -2,-0.3 2,-1.4 1,-0.2 3,-0.2 0.610 68.7 81.9 -93.0 -18.6 38.7 17.6 1.8 25 40 A N > + 0 0 70 1,-0.2 3,-0.7 2,-0.1 -1,-0.2 -0.529 50.7 145.7 -88.1 67.3 36.3 14.9 3.1 26 41 A K G > + 0 0 36 -2,-1.4 3,-2.0 1,-0.2 4,-0.2 0.657 41.3 90.8 -80.6 -19.1 35.6 16.6 6.5 27 42 A E G > + 0 0 17 1,-0.3 3,-1.4 -3,-0.2 4,-0.5 0.654 68.7 79.9 -58.9 -17.7 32.0 15.6 7.0 28 43 A I G <> + 0 0 0 -3,-0.7 4,-2.1 1,-0.3 -1,-0.3 0.706 65.9 84.2 -64.1 -23.6 33.0 12.5 8.9 29 44 A F H <> S+ 0 0 0 -3,-2.0 4,-2.2 96,-0.2 -1,-0.3 0.844 91.5 54.6 -45.0 -32.0 33.7 14.3 12.2 30 45 A L H <> S+ 0 0 1 -3,-1.4 4,-3.0 2,-0.2 5,-0.5 0.968 103.4 50.2 -71.1 -52.7 29.9 13.9 12.7 31 46 A R H > S+ 0 0 59 -4,-0.5 4,-3.4 1,-0.2 5,-0.3 0.954 111.8 51.4 -46.1 -60.0 29.9 10.1 12.2 32 47 A E H X S+ 0 0 13 -4,-2.1 4,-1.1 1,-0.2 -1,-0.2 0.859 114.3 41.0 -45.9 -52.1 32.7 9.9 14.8 33 48 A L H X S+ 0 0 6 -4,-2.2 4,-2.8 2,-0.2 3,-0.3 0.923 116.6 46.6 -68.5 -48.1 30.9 12.1 17.4 34 49 A I H X S+ 0 0 0 -4,-3.0 4,-2.8 1,-0.2 -1,-0.2 0.883 111.1 54.4 -57.8 -40.2 27.4 10.5 17.0 35 50 A S H X S+ 0 0 38 -4,-3.4 4,-1.6 -5,-0.5 -1,-0.2 0.782 106.8 50.8 -70.4 -22.0 29.1 7.2 17.1 36 51 A N H X S+ 0 0 57 -4,-1.1 4,-3.0 -3,-0.3 -2,-0.2 0.939 108.6 51.1 -72.7 -50.6 30.7 8.2 20.4 37 52 A S H X S+ 0 0 7 -4,-2.8 4,-3.0 2,-0.2 5,-0.2 0.963 107.7 54.4 -39.9 -61.0 27.2 9.3 21.8 38 53 A S H X S+ 0 0 15 -4,-2.8 4,-2.5 1,-0.2 -1,-0.2 0.891 109.6 46.1 -44.4 -54.1 25.9 5.8 20.7 39 54 A D H X S+ 0 0 78 -4,-1.6 4,-1.8 1,-0.2 -1,-0.2 0.946 112.3 51.3 -55.9 -49.9 28.7 4.0 22.7 40 55 A A H X S+ 0 0 19 -4,-3.0 41,-1.6 1,-0.2 4,-1.4 0.903 112.4 46.2 -54.1 -41.8 28.0 6.3 25.7 41 56 A L H X S+ 0 0 0 -4,-3.0 4,-2.2 39,-0.3 -1,-0.2 0.862 106.3 59.6 -68.9 -37.2 24.2 5.4 25.4 42 57 A D H X S+ 0 0 78 -4,-2.5 4,-3.5 -5,-0.2 -1,-0.2 0.890 104.7 51.1 -49.8 -48.5 25.0 1.7 25.1 43 58 A K H X S+ 0 0 128 -4,-1.8 4,-3.4 2,-0.2 -1,-0.2 0.881 108.8 46.8 -68.2 -45.8 26.8 1.7 28.5 44 59 A I H X S+ 0 0 0 -4,-1.4 4,-2.8 2,-0.2 -1,-0.2 0.907 115.4 48.1 -64.1 -41.5 24.0 3.4 30.5 45 60 A R H X S+ 0 0 110 -4,-2.2 4,-1.6 2,-0.2 -2,-0.2 0.948 111.9 49.1 -58.5 -49.7 21.6 0.9 28.9 46 61 A Y H >X S+ 0 0 169 -4,-3.5 4,-0.6 1,-0.2 3,-0.5 0.964 115.6 45.1 -49.7 -51.0 24.0 -2.0 29.7 47 62 A E H >X S+ 0 0 60 -4,-3.4 4,-2.1 1,-0.2 3,-0.7 0.853 106.9 57.6 -64.5 -38.8 24.2 -0.6 33.3 48 63 A S H 3< S+ 0 0 18 -4,-2.8 -1,-0.2 1,-0.2 -2,-0.2 0.830 92.5 70.6 -60.8 -33.0 20.4 -0.1 33.6 49 64 A L H << S+ 0 0 134 -4,-1.6 -1,-0.2 -3,-0.5 -2,-0.2 0.862 114.2 25.7 -52.8 -40.7 19.7 -3.8 32.8 50 65 A T H << S+ 0 0 117 -3,-0.7 -1,-0.2 -4,-0.6 -2,-0.2 0.759 137.4 30.4 -95.3 -36.4 21.2 -4.8 36.2 51 66 A D >< - 0 0 58 -4,-2.1 3,-1.0 1,-0.1 4,-0.4 -0.901 67.0-177.1-121.0 101.6 20.5 -1.5 38.2 52 67 A P T 3 S+ 0 0 102 0, 0.0 3,-0.2 0, 0.0 -4,-0.1 0.572 78.8 65.0 -79.2 -7.5 17.3 0.1 36.7 53 68 A S T > S+ 0 0 60 1,-0.2 3,-2.5 2,-0.1 4,-0.2 0.616 77.6 79.1 -86.6 -16.7 17.7 3.2 39.0 54 69 A K G X S+ 0 0 63 -3,-1.0 3,-0.8 1,-0.3 -1,-0.2 0.889 89.5 63.2 -56.5 -32.5 21.0 4.3 37.4 55 70 A L G 3 S+ 0 0 21 -4,-0.4 3,-0.5 1,-0.2 -1,-0.3 0.172 71.2 101.0 -69.1 12.8 18.4 5.5 34.8 56 71 A D G < S+ 0 0 131 -3,-2.5 2,-1.0 1,-0.2 -1,-0.2 0.847 72.8 63.1 -68.2 -34.2 16.9 7.9 37.5 57 72 A S S < S- 0 0 30 -3,-0.8 -1,-0.2 1,-0.3 -2,-0.1 -0.325 131.4 -19.7 -81.9 46.6 18.8 10.8 35.9 58 73 A G - 0 0 31 -2,-1.0 -1,-0.3 -3,-0.5 -2,-0.0 0.373 54.4-156.0 108.8 112.2 16.9 10.5 32.6 59 74 A K S S+ 0 0 172 -3,-0.2 2,-0.4 2,-0.0 -3,-0.1 0.330 72.7 80.5 -94.6 3.3 15.0 7.4 31.3 60 75 A E - 0 0 122 -5,-0.0 2,-0.5 2,-0.0 19,-0.0 -0.962 63.2-154.4-127.0 133.8 15.3 8.3 27.6 61 76 A L + 0 0 22 -2,-0.4 2,-0.3 17,-0.1 19,-0.1 -0.903 35.2 125.1-120.3 116.7 18.3 7.7 25.4 62 77 A H - 0 0 28 -2,-0.5 17,-1.2 139,-0.2 2,-0.4 -0.960 48.5-121.1-165.6 163.9 18.8 9.8 22.3 63 78 A I E -Bc 78 203A 0 139,-2.5 141,-2.7 -2,-0.3 2,-0.4 -0.972 21.6-168.9-123.7 131.8 21.0 12.2 20.3 64 79 A N E -Bc 77 204A 23 13,-2.7 13,-2.6 -2,-0.4 2,-0.5 -0.979 10.2-152.3-118.8 138.7 19.9 15.7 19.3 65 80 A L E -Bc 76 205A 0 139,-2.7 141,-2.1 -2,-0.4 11,-0.2 -0.975 15.8-169.9-111.4 117.5 21.8 17.8 16.7 66 81 A I E -B 75 0A 48 9,-3.4 9,-2.7 -2,-0.5 2,-0.2 -0.915 1.9-168.0-124.3 104.3 21.5 21.5 17.5 67 82 A P E -B 74 0A 8 0, 0.0 2,-0.2 0, 0.0 7,-0.2 -0.447 6.6-177.0 -80.6 150.6 22.7 24.1 14.9 68 83 A N E >> -B 73 0A 48 5,-1.2 5,-1.6 -2,-0.2 4,-1.0 -0.707 9.3-175.0-158.6 96.7 23.0 27.8 15.7 69 84 A K T 45S+ 0 0 85 -2,-0.2 -1,-0.1 3,-0.2 5,-0.0 0.826 86.2 56.1 -62.6 -37.4 24.1 30.0 12.7 70 85 A Q T 45S+ 0 0 153 1,-0.2 -1,-0.2 2,-0.1 -2,-0.0 0.972 115.0 33.0 -58.0 -67.5 24.3 33.0 15.0 71 86 A D T 45S- 0 0 116 2,-0.1 -1,-0.2 1,-0.1 -2,-0.2 0.538 106.6-128.3 -65.8 -13.9 26.8 31.6 17.7 72 87 A R T <5 + 0 0 73 -4,-1.0 103,-2.5 1,-0.2 2,-0.4 0.825 63.5 130.3 59.9 41.0 28.4 29.7 14.8 73 88 A T E < -BD 68 174A 9 -5,-1.6 -5,-1.2 101,-0.2 2,-0.5 -0.936 50.2-154.0-121.1 144.9 28.2 26.3 16.7 74 89 A L E -BD 67 173A 0 99,-1.9 99,-3.0 -2,-0.4 2,-0.5 -0.978 22.8-162.9-102.7 128.0 27.0 22.8 16.0 75 90 A T E -BD 66 172A 18 -9,-2.7 -9,-3.4 -2,-0.5 2,-0.5 -0.956 10.1-165.0-119.5 124.3 26.0 21.1 19.3 76 91 A I E -BD 65 171A 2 95,-1.9 95,-2.2 -2,-0.5 2,-0.4 -0.907 14.4-173.0-104.3 121.6 25.5 17.3 19.7 77 92 A V E +BD 64 170A 17 -13,-2.6 -13,-2.7 -2,-0.5 2,-0.3 -0.968 7.9 170.2-121.4 131.8 23.7 16.3 22.9 78 93 A D E -BD 63 169A 5 91,-2.7 91,-1.4 -2,-0.4 -15,-0.2 -0.948 34.3-140.5-134.2 161.6 23.2 12.9 24.2 79 94 A T + 0 0 24 -17,-1.2 89,-0.2 -2,-0.3 -16,-0.1 -0.139 58.4 129.9-111.6 39.1 21.9 11.4 27.4 80 95 A G S S- 0 0 0 89,-0.2 -39,-0.3 -18,-0.1 -40,-0.1 0.328 77.4 -64.0 -72.1-157.9 24.4 8.5 27.6 81 96 A I - 0 0 21 -41,-1.6 59,-0.5 1,-0.1 87,-0.1 0.668 68.6-150.0 -68.2 -26.1 26.6 7.4 30.6 82 97 A G - 0 0 3 57,-0.2 2,-0.3 85,-0.1 57,-0.2 0.021 14.2 -89.7 77.9 171.4 28.8 10.6 30.8 83 98 A M - 0 0 30 85,-0.3 56,-0.4 56,-0.1 62,-0.2 -0.876 22.6-126.5-120.3 158.9 32.3 10.9 32.0 84 99 A T > - 0 0 30 -2,-0.3 4,-1.9 54,-0.1 3,-0.2 -0.525 38.4-106.2 -84.6 165.0 34.1 11.6 35.4 85 100 A K H > S+ 0 0 58 1,-0.2 4,-1.5 2,-0.2 5,-0.1 0.820 125.0 57.4 -55.9 -30.7 36.5 14.4 35.5 86 101 A A H > S+ 0 0 55 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.865 105.0 50.0 -70.9 -35.6 39.2 11.7 35.6 87 102 A D H 4>S+ 0 0 60 -3,-0.2 6,-2.0 1,-0.2 5,-1.0 0.909 108.8 51.4 -66.1 -44.2 37.9 10.3 32.3 88 103 A L H <5S+ 0 0 0 -4,-1.9 3,-0.5 4,-0.3 4,-0.4 0.818 111.0 47.8 -64.8 -33.8 38.0 13.7 30.6 89 104 A I H <5S+ 0 0 41 -4,-1.5 2,-2.0 1,-0.3 -1,-0.2 0.942 102.5 65.1 -74.4 -43.7 41.5 14.2 31.7 90 105 A N T X5S- 0 0 107 -4,-2.2 4,-0.8 1,-0.2 3,-0.5 -0.283 136.4 -74.6 -78.0 51.4 42.5 10.8 30.5 91 106 A N T 45S- 0 0 20 -2,-2.0 5,-0.2 -3,-0.5 -3,-0.2 0.700 85.2 -59.2 68.6 32.5 41.8 11.7 26.9 92 107 A L T 4> + 0 0 129 25,-0.3 4,-2.1 -2,-0.2 3,-1.8 -0.303 52.1 157.6-108.8 41.6 43.5 5.0 24.9 96 111 A A H 3> + 0 0 0 1,-0.3 4,-2.5 2,-0.2 5,-0.3 0.742 57.4 63.5 -30.6 -53.0 44.7 7.9 22.8 97 112 A K H 34 S+ 0 0 107 1,-0.2 4,-0.5 2,-0.2 -1,-0.3 0.869 118.0 29.1 -52.9 -36.4 48.4 7.5 23.4 98 113 A S H <> S+ 0 0 65 -3,-1.8 4,-2.5 2,-0.2 -2,-0.2 0.794 115.2 58.4 -93.3 -36.0 48.3 4.1 21.6 99 114 A G H X S+ 0 0 6 -4,-2.1 4,-2.9 1,-0.2 -3,-0.2 0.869 107.2 51.8 -60.2 -38.0 45.4 4.7 19.2 100 115 A T H X S+ 0 0 1 -4,-2.5 4,-2.9 -5,-0.2 -1,-0.2 0.839 108.4 50.7 -64.7 -35.7 47.5 7.6 17.8 101 116 A K H > S+ 0 0 141 -4,-0.5 4,-2.8 -5,-0.3 -2,-0.2 0.948 114.7 42.7 -65.6 -49.3 50.5 5.2 17.4 102 117 A A H X S+ 0 0 41 -4,-2.5 4,-2.2 2,-0.2 -2,-0.2 0.938 119.5 44.1 -55.5 -51.2 48.3 2.6 15.5 103 118 A F H X S+ 0 0 0 -4,-2.9 4,-2.5 2,-0.2 -2,-0.2 0.965 113.6 50.0 -63.2 -54.3 46.6 5.4 13.5 104 119 A M H X S+ 0 0 53 -4,-2.9 4,-1.0 1,-0.3 -1,-0.2 0.904 111.2 49.3 -47.4 -52.3 49.9 7.2 12.8 105 120 A E H X S+ 0 0 131 -4,-2.8 4,-0.5 1,-0.2 -1,-0.3 0.879 111.5 51.2 -55.8 -41.5 51.4 3.9 11.7 106 121 A A H >< S+ 0 0 25 -4,-2.2 3,-0.8 1,-0.2 5,-0.5 0.893 101.6 60.9 -67.2 -39.5 48.4 3.4 9.4 107 122 A L H >< S+ 0 0 36 -4,-2.5 3,-0.6 1,-0.2 -1,-0.2 0.797 103.6 44.8 -60.4 -41.3 48.5 6.8 7.7 108 123 A Q H 3< S+ 0 0 106 -4,-1.0 -1,-0.2 -3,-0.2 -2,-0.1 0.616 112.5 56.6 -79.4 -13.2 52.0 6.7 6.0 109 124 A A T << S- 0 0 86 -3,-0.8 2,-0.6 -4,-0.5 -1,-0.2 -0.338 133.4 -67.3-113.3 42.0 51.2 3.1 4.8 110 125 A G S < S+ 0 0 67 -3,-0.6 -3,-0.1 1,-0.3 -4,-0.1 -0.673 92.3 116.3 111.3 -82.8 47.9 3.7 2.8 111 126 A A - 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