==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=5-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 25-SEP-07 2VCM . COMPND 2 MOLECULE: ISOPENICILLIN N SYNTHETASE; . SOURCE 2 ORGANISM_SCIENTIFIC: EMERICELLA NIDULANS; . AUTHOR W.GE,I.J.CLIFTON,R.M.ADLINGTON,J.E.BALDWIN,P.J.RUTLEDGE . 329 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14831.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 219 66.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 8 2.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 58 17.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 28 8.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 32 9.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 79 24.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 2 4 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A S 0 0 185 0, 0.0 2,-0.6 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -1.3 16.2 -28.3 -0.2 2 4 A V - 0 0 80 236,-0.0 236,-0.1 234,-0.0 234,-0.1 -0.796 360.0-153.7 -95.0 119.7 15.9 -24.5 -0.1 3 5 A S - 0 0 63 -2,-0.6 236,-2.5 234,-0.5 2,-0.4 -0.217 14.3-110.0 -92.1 178.3 16.4 -22.9 -3.5 4 6 A K B -a 239 0A 127 234,-0.3 236,-0.2 226,-0.1 2,-0.1 -0.914 27.1-120.5-117.4 137.2 17.6 -19.5 -4.3 5 7 A A - 0 0 15 234,-2.9 2,-0.8 -2,-0.4 236,-0.3 -0.443 24.7-115.8 -74.3 143.3 15.5 -16.7 -5.9 6 8 A N + 0 0 100 -2,-0.1 31,-0.4 234,-0.1 33,-0.4 -0.727 42.1 170.6 -74.0 111.9 16.4 -15.2 -9.2 7 9 A V - 0 0 22 -2,-0.8 33,-0.2 31,-0.1 34,-0.0 -0.843 20.5-151.2-127.6 92.5 17.2 -11.6 -8.3 8 10 A P - 0 0 39 0, 0.0 33,-2.9 0, 0.0 2,-0.6 -0.259 11.8-127.3 -68.2 148.3 18.7 -9.9 -11.3 9 11 A K E -f 41 0B 118 31,-0.2 2,-0.5 33,-0.1 33,-0.2 -0.888 29.6-167.9 -91.1 122.9 21.1 -7.0 -11.0 10 12 A I E -f 42 0B 0 31,-3.4 33,-2.4 -2,-0.6 2,-0.9 -0.955 20.2-135.3-119.7 121.7 19.8 -4.1 -13.1 11 13 A D E -f 43 0B 66 -2,-0.5 33,-0.2 31,-0.2 31,-0.1 -0.711 23.4-177.3 -76.2 109.2 21.9 -1.1 -13.9 12 14 A V > + 0 0 1 31,-2.0 3,-2.0 -2,-0.9 4,-0.4 0.374 49.8 106.8 -88.2 1.8 19.5 1.7 -13.3 13 15 A S G > S+ 0 0 45 30,-0.4 3,-2.0 1,-0.3 4,-0.2 0.864 70.7 63.3 -56.0 -37.8 21.8 4.6 -14.3 14 16 A P G > S+ 0 0 34 0, 0.0 3,-2.0 0, 0.0 5,-0.3 0.805 90.2 69.0 -57.7 -24.2 20.0 5.2 -17.6 15 17 A L G < S+ 0 0 3 -3,-2.0 -2,-0.2 1,-0.3 141,-0.1 0.684 96.9 53.8 -69.2 -14.3 16.8 6.2 -15.6 16 18 A F G < S+ 0 0 110 -3,-2.0 -1,-0.3 -4,-0.4 2,-0.1 0.407 110.2 60.2 -89.3 -1.2 18.8 9.3 -14.5 17 19 A G S < S- 0 0 25 -3,-2.0 6,-0.0 -4,-0.2 0, 0.0 -0.344 84.2-110.1-119.5-165.2 19.5 10.3 -18.0 18 20 A D S S+ 0 0 140 -2,-0.1 2,-1.1 5,-0.0 3,-0.1 0.179 72.4 112.7-120.0 14.5 18.0 11.2 -21.4 19 21 A D > - 0 0 94 -5,-0.3 4,-2.1 1,-0.2 5,-0.2 -0.774 48.2-170.1 -86.1 100.9 18.8 8.2 -23.6 20 22 A Q H > S+ 0 0 101 -2,-1.1 4,-2.2 1,-0.2 -1,-0.2 0.908 80.2 50.4 -70.0 -38.0 15.2 7.0 -24.0 21 23 A A H > S+ 0 0 52 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.925 109.6 51.5 -64.2 -39.4 15.9 3.7 -25.6 22 24 A A H > S+ 0 0 12 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.902 108.4 53.0 -61.8 -40.1 18.4 2.8 -22.8 23 25 A K H X S+ 0 0 4 -4,-2.1 4,-2.7 -9,-0.2 -1,-0.2 0.905 106.8 52.1 -58.7 -42.6 15.6 3.7 -20.4 24 26 A M H X S+ 0 0 103 -4,-2.2 4,-2.2 1,-0.2 -2,-0.2 0.905 105.6 54.4 -61.6 -36.8 13.3 1.3 -22.2 25 27 A R H X S+ 0 0 149 -4,-2.2 4,-1.2 2,-0.2 -1,-0.2 0.851 109.9 47.4 -65.1 -33.1 15.9 -1.4 -21.9 26 28 A V H X S+ 0 0 4 -4,-1.7 4,-2.3 2,-0.2 3,-0.4 0.941 109.5 53.6 -68.0 -50.4 16.0 -0.8 -18.1 27 29 A A H X S+ 0 0 2 -4,-2.7 4,-2.8 1,-0.2 -2,-0.2 0.843 104.3 56.0 -53.4 -38.1 12.2 -0.9 -18.0 28 30 A Q H X S+ 0 0 115 -4,-2.2 4,-2.4 2,-0.2 -1,-0.2 0.897 107.8 47.6 -62.0 -40.9 12.2 -4.3 -19.8 29 31 A Q H X S+ 0 0 72 -4,-1.2 4,-2.2 -3,-0.4 -2,-0.2 0.878 111.0 50.8 -68.7 -38.4 14.4 -5.7 -17.1 30 32 A I H X S+ 0 0 0 -4,-2.3 4,-2.5 2,-0.2 -2,-0.2 0.932 110.7 50.1 -63.0 -44.2 12.2 -4.3 -14.3 31 33 A D H X S+ 0 0 40 -4,-2.8 4,-1.9 1,-0.2 -2,-0.2 0.941 110.5 49.8 -57.7 -48.3 9.1 -5.8 -16.0 32 34 A A H < S+ 0 0 44 -4,-2.4 4,-0.5 1,-0.2 -1,-0.2 0.917 113.9 43.9 -60.1 -45.5 10.8 -9.2 -16.2 33 35 A A H ><>S+ 0 0 4 -4,-2.2 5,-2.6 1,-0.2 3,-0.9 0.894 111.5 54.3 -62.4 -40.5 11.8 -9.1 -12.6 34 36 A S H 3<5S+ 0 0 4 -4,-2.5 230,-0.5 1,-0.3 -2,-0.2 0.795 111.1 45.0 -70.0 -27.8 8.4 -7.9 -11.5 35 37 A R T 3<5S+ 0 0 94 -4,-1.9 -1,-0.3 -5,-0.2 -2,-0.2 0.455 117.5 47.3 -90.9 -3.7 6.7 -10.7 -13.3 36 38 A D T < 5S- 0 0 93 -3,-0.9 -3,-0.1 -4,-0.5 -2,-0.1 0.498 135.9 -26.0-104.1-109.6 9.1 -13.4 -12.0 37 39 A T T 5S- 0 0 16 -31,-0.4 -3,-0.2 2,-0.2 -4,-0.1 0.649 82.7-122.3 -82.9 -17.3 10.0 -13.4 -8.2 38 40 A G S + 0 0 91 -2,-0.4 4,-1.4 1,-0.2 3,-0.1 -0.666 34.5 172.5 -80.6 95.3 27.1 6.3 -1.0 49 51 A V H > S+ 0 0 2 -2,-1.4 4,-1.8 1,-0.2 -1,-0.2 0.645 70.1 66.6 -86.2 -13.3 25.9 3.2 0.9 50 52 A Q H > S+ 0 0 105 2,-0.2 4,-1.9 1,-0.1 -1,-0.2 0.923 105.6 43.8 -66.4 -42.3 29.1 2.9 2.9 51 53 A R H > S+ 0 0 104 1,-0.2 4,-2.7 2,-0.2 5,-0.3 0.932 110.2 56.5 -73.8 -38.0 28.4 6.2 4.6 52 54 A L H X S+ 0 0 2 -4,-1.4 4,-2.0 1,-0.2 5,-0.2 0.957 112.3 41.0 -50.8 -51.4 24.7 5.2 5.1 53 55 A S H X S+ 0 0 28 -4,-1.8 4,-2.2 2,-0.2 -1,-0.2 0.869 114.9 52.0 -73.4 -30.7 25.7 2.1 7.0 54 56 A Q H X S+ 0 0 127 -4,-1.9 4,-2.3 1,-0.2 5,-0.2 0.973 113.5 41.8 -68.9 -53.6 28.5 3.8 9.0 55 57 A K H X S+ 0 0 47 -4,-2.7 4,-1.4 1,-0.2 -1,-0.2 0.842 114.3 53.2 -60.5 -34.6 26.4 6.6 10.2 56 58 A T H X S+ 0 0 0 -4,-2.0 4,-2.3 -5,-0.3 -1,-0.2 0.923 109.9 48.3 -67.6 -41.6 23.5 4.2 10.9 57 59 A K H X S+ 0 0 128 -4,-2.2 4,-1.8 1,-0.2 -2,-0.2 0.857 105.5 55.9 -67.4 -39.6 25.7 2.0 13.0 58 60 A E H X S+ 0 0 82 -4,-2.3 4,-1.2 2,-0.2 -1,-0.2 0.887 111.3 47.8 -63.0 -33.1 27.2 4.8 15.1 59 61 A F H X S+ 0 0 0 -4,-1.4 4,-2.0 -5,-0.2 3,-0.4 0.970 110.9 45.9 -69.7 -57.8 23.6 5.8 16.0 60 62 A H H < S+ 0 0 6 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.857 116.2 47.8 -54.7 -37.7 22.3 2.4 17.0 61 63 A M H < S+ 0 0 106 -4,-1.8 -1,-0.2 -5,-0.2 -2,-0.2 0.780 116.9 39.6 -81.9 -22.8 25.5 1.6 19.1 62 64 A S H < S+ 0 0 62 -4,-1.2 -2,-0.2 -3,-0.4 -1,-0.2 0.631 83.7 106.8-108.5 -12.9 25.6 4.9 21.0 63 65 A I < - 0 0 12 -4,-2.0 70,-0.0 -5,-0.1 -4,-0.0 -0.432 58.8-144.9 -71.2 136.7 22.0 5.7 21.9 64 66 A T > - 0 0 55 -2,-0.1 4,-2.0 1,-0.1 3,-0.2 -0.586 24.3-105.1-101.4 166.4 21.2 5.2 25.6 65 67 A P H > S+ 0 0 94 0, 0.0 4,-2.3 0, 0.0 5,-0.2 0.886 119.7 56.4 -62.3 -34.2 18.0 4.0 27.2 66 68 A E H > S+ 0 0 118 1,-0.2 4,-2.0 2,-0.2 5,-0.1 0.918 109.1 46.5 -59.7 -44.2 17.2 7.5 28.4 67 69 A E H > S+ 0 0 11 -3,-0.2 4,-1.4 2,-0.2 -1,-0.2 0.867 108.8 55.5 -66.4 -36.8 17.3 8.8 24.8 68 70 A K H X S+ 0 0 32 -4,-2.0 4,-0.8 1,-0.2 3,-0.3 0.915 108.5 47.0 -67.5 -41.2 15.2 5.8 23.6 69 71 A W H >< S+ 0 0 132 -4,-2.3 3,-0.8 1,-0.2 -1,-0.2 0.925 110.7 53.9 -62.7 -40.6 12.4 6.7 26.0 70 72 A D H 3< S+ 0 0 109 -4,-2.0 -1,-0.2 1,-0.2 -2,-0.2 0.799 118.9 33.9 -62.2 -28.9 12.7 10.3 25.0 71 73 A L H 3< S+ 0 0 11 -4,-1.4 17,-2.1 -3,-0.3 -1,-0.2 0.413 91.5 133.9-104.5 -2.1 12.3 9.4 21.3 72 74 A A B << -h 88 0B 0 -4,-0.8 17,-0.2 -3,-0.8 11,-0.1 -0.170 54.8-124.8 -63.0 139.4 9.9 6.4 21.8 73 75 A I >> - 0 0 3 15,-2.4 3,-2.4 12,-0.1 4,-1.0 -0.278 41.2 -93.3 -68.2 168.9 6.7 6.0 19.7 74 76 A R T 34 S+ 0 0 110 9,-3.2 10,-0.1 6,-0.5 -1,-0.1 0.741 120.6 72.1 -66.8 -17.7 3.5 5.7 21.7 75 77 A A T 34 S+ 0 0 52 8,-0.3 -1,-0.3 1,-0.2 3,-0.1 0.795 114.4 26.5 -61.5 -25.7 3.7 1.9 21.7 76 78 A Y T <4 S+ 0 0 43 -3,-2.4 2,-0.3 1,-0.2 -2,-0.2 0.475 129.2 39.1-113.0 -8.2 6.5 2.3 24.2 77 79 A N >< - 0 0 25 -4,-1.0 3,-2.2 3,-0.1 -1,-0.2 -0.817 58.7-161.1-150.2 103.6 5.8 5.7 25.8 78 80 A K T 3 S+ 0 0 179 -2,-0.3 3,-0.3 1,-0.3 -4,-0.1 0.644 89.9 68.5 -59.0 -19.1 2.2 6.8 26.7 79 81 A E T 3 S+ 0 0 168 1,-0.2 2,-0.5 2,-0.1 -1,-0.3 0.641 89.0 67.6 -75.6 -15.3 3.3 10.4 26.8 80 82 A H X + 0 0 37 -3,-2.2 3,-2.2 1,-0.2 -6,-0.5 -0.426 54.4 152.8-101.6 58.4 3.9 10.4 23.1 81 83 A Q T 3 S+ 0 0 96 -2,-0.5 -1,-0.2 -3,-0.3 -2,-0.1 0.741 71.5 56.5 -66.5 -20.3 0.4 10.1 21.7 82 84 A D T 3 S+ 0 0 146 -3,-0.2 2,-1.1 1,-0.1 3,-0.3 0.573 87.9 87.3 -85.0 -5.7 1.3 11.9 18.5 83 85 A Q < + 0 0 21 -3,-2.2 -9,-3.2 1,-0.2 -8,-0.3 -0.726 39.5 133.6 -98.9 88.1 4.1 9.5 17.7 84 86 A V S S+ 0 0 71 -2,-1.1 -1,-0.2 -11,-0.2 -9,-0.1 0.850 85.3 10.0 -99.4 -41.8 2.5 6.7 15.8 85 87 A R S S+ 0 0 16 -3,-0.3 2,-0.4 1,-0.1 17,-0.1 0.867 114.8 66.4-103.3 -50.5 5.0 6.3 13.0 86 88 A A S S+ 0 0 0 15,-0.1 2,-0.3 38,-0.1 17,-0.2 -0.670 80.4 41.3 -92.0 135.2 8.1 8.4 13.7 87 89 A G E S- I 0 102B 0 15,-2.0 15,-2.6 -2,-0.4 2,-0.4 -0.909 90.0 -25.3 135.9-162.2 10.5 7.7 16.5 88 90 A Y E -hI 72 101B 0 -17,-2.1 -15,-2.4 -2,-0.3 2,-0.7 -0.710 38.9-158.2 -95.9 136.6 12.3 4.9 18.3 89 91 A Y E - I 0 100B 28 11,-3.1 11,-2.0 -2,-0.4 2,-0.1 -0.941 29.1-139.1-113.4 102.6 10.9 1.4 18.4 90 92 A L - 0 0 14 -2,-0.7 2,-0.1 9,-0.2 8,-0.1 -0.350 2.7-131.9 -74.4 148.8 12.6 -0.2 21.4 91 93 A S - 0 0 26 6,-0.1 6,-0.2 -2,-0.1 8,-0.1 -0.388 17.9-139.4 -78.7 167.9 14.0 -3.7 21.8 92 94 A I B >> -O 96 0C 77 4,-2.3 3,-2.9 6,-0.1 4,-2.7 -0.881 22.4-125.5-131.1 97.8 12.9 -5.5 25.0 93 95 A P T 34 S+ 0 0 119 0, 0.0 4,-0.1 0, 0.0 0, 0.0 -0.188 94.4 13.7 -54.8 137.9 15.9 -7.4 26.5 94 96 A G T 34 S+ 0 0 58 98,-0.1 102,-0.4 1,-0.1 101,-0.2 0.250 136.9 41.9 85.7 -9.8 15.2 -11.0 26.9 95 97 A K T <4 S+ 0 0 131 -3,-2.9 2,-0.4 1,-0.3 -1,-0.1 0.649 111.7 30.8-133.5 -47.1 12.1 -10.8 24.8 96 98 A K B < -O 92 0C 29 -4,-2.7 -4,-2.3 1,-0.1 -1,-0.3 -0.989 51.6-175.2-132.6 123.0 12.4 -8.7 21.6 97 99 A A + 0 0 7 -2,-0.4 -6,-0.1 -6,-0.2 -1,-0.1 0.857 56.6 80.7 -87.0 -48.1 15.6 -8.3 19.6 98 100 A V + 0 0 28 89,-0.1 2,-0.3 110,-0.1 89,-0.2 -0.367 50.8 178.4 -68.9 145.1 15.0 -5.9 16.9 99 101 A E E + J 0 186B 7 87,-1.7 87,-3.2 -8,-0.1 2,-0.3 -0.979 6.1 174.2-139.4 155.3 15.1 -2.1 17.4 100 102 A S E -IJ 89 185B 5 -11,-2.0 -11,-3.1 -2,-0.3 2,-0.4 -0.964 27.6-138.8-157.8 162.8 14.6 0.7 14.9 101 103 A F E -IJ 88 184B 0 83,-1.2 83,-2.8 -2,-0.3 2,-0.4 -0.984 22.8-163.8-132.3 124.5 14.2 4.4 14.3 102 104 A C E +IJ 87 183B 6 -15,-2.6 -15,-2.0 -2,-0.4 2,-0.3 -0.871 8.7 178.4-111.9 135.7 11.6 5.6 11.8 103 105 A Y E - 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0 0 175 -3,-1.1 -3,-0.2 -4,-0.2 -2,-0.1 0.894 38.6-177.2 54.9 40.3 -3.7 17.2 11.9 119 121 A T > < - 0 0 14 -5,-2.6 3,-1.5 -6,-0.1 -1,-0.2 -0.528 31.4-101.5 -68.7 135.5 -4.2 14.8 8.9 120 122 A P T 3 S+ 0 0 63 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.085 103.2 26.0 -55.6 154.2 -3.6 11.2 9.9 121 123 A T T 3 S+ 0 0 23 1,-0.2 2,-0.5 -3,-0.1 -2,-0.1 0.227 97.2 106.5 74.3 -6.6 -0.3 9.5 8.9 122 124 A H < + 0 0 15 -3,-1.5 2,-0.3 -8,-0.2 -1,-0.2 -0.871 42.0 159.0-104.2 129.0 1.6 12.9 9.0 123 125 A E - 0 0 17 -2,-0.5 2,-0.5 -18,-0.1 -15,-0.1 -0.981 42.3-111.3-142.3 159.3 3.9 13.6 11.9 124 126 A V - 0 0 58 -2,-0.3 -15,-0.1 -42,-0.1 -38,-0.1 -0.784 45.3-110.0 -90.6 127.8 6.8 15.8 12.7 125 127 A N - 0 0 16 -2,-0.5 2,-0.4 -17,-0.5 -22,-0.1 -0.182 23.1-142.8 -55.6 146.3 10.1 13.9 13.0 126 128 A V - 0 0 37 -55,-0.1 -39,-0.1 0, 0.0 -1,-0.1 -0.898 20.4-170.2-111.8 141.4 11.7 13.5 16.4 127 129 A W - 0 0 43 -2,-0.4 3,-0.1 -24,-0.0 -24,-0.0 -0.936 22.4-108.2-132.9 150.4 15.5 13.6 16.6 128 130 A P - 0 0 16 0, 0.0 2,-0.2 0, 0.0 9,-0.1 -0.214 55.8 -72.6 -68.2 165.2 18.2 12.9 19.2 129 131 A D > - 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