==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=5-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 27-OCT-07 2VEW . COMPND 2 MOLECULE: TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR B.DOUTY,B.WAYLAND,P.J.ALA,M.J.BOWER,J.PRUITT,L.BOSTROM, . 296 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13790.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 208 70.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 14 4.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 39 13.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 3 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 26 8.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 29 9.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 86 29.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 1 1 2 1 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 2 1 0 0 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A M > 0 0 38 0, 0.0 4,-1.9 0, 0.0 5,-0.1 0.000 360.0 360.0 360.0 -38.5 43.8 11.6 73.1 2 4 A E H > + 0 0 115 2,-0.2 4,-2.2 1,-0.2 5,-0.1 0.668 360.0 60.7 -76.3 -13.0 45.2 14.4 75.2 3 5 A K H > S+ 0 0 170 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.921 107.2 44.1 -75.6 -45.7 46.8 16.0 72.1 4 6 A E H > S+ 0 0 62 2,-0.2 4,-2.1 1,-0.2 5,-0.2 0.925 114.0 51.8 -61.6 -43.8 43.3 16.4 70.6 5 7 A F H X S+ 0 0 20 -4,-1.9 4,-2.6 1,-0.2 3,-0.2 0.949 109.3 49.5 -56.1 -52.3 42.0 17.7 73.9 6 8 A E H X S+ 0 0 116 -4,-2.2 4,-2.2 1,-0.2 -1,-0.2 0.860 112.8 46.9 -56.4 -39.2 44.8 20.2 74.2 7 9 A Q H X S+ 0 0 97 -4,-2.1 4,-2.0 2,-0.2 -1,-0.2 0.777 109.6 52.5 -77.6 -26.1 44.1 21.5 70.6 8 10 A I H X>S+ 0 0 9 -4,-2.1 5,-1.9 -3,-0.2 4,-1.6 0.918 111.7 48.5 -70.8 -43.0 40.3 21.7 71.2 9 11 A D H <5S+ 0 0 63 -4,-2.6 -2,-0.2 -5,-0.2 -3,-0.2 0.938 112.9 46.3 -59.2 -49.2 41.1 23.8 74.3 10 12 A K H <5S+ 0 0 172 -4,-2.2 -1,-0.2 1,-0.2 -2,-0.2 0.897 116.0 45.0 -62.6 -42.2 43.5 26.1 72.4 11 13 A S H <5S- 0 0 75 -4,-2.0 -1,-0.2 -5,-0.1 -2,-0.2 0.731 103.1-134.6 -73.0 -22.6 41.1 26.5 69.5 12 14 A G T <5 + 0 0 61 -4,-1.6 3,-0.2 -5,-0.1 4,-0.2 0.907 58.5 139.7 67.5 42.8 38.2 27.0 71.9 13 15 A S >< + 0 0 31 -5,-1.9 4,-2.6 1,-0.2 5,-0.2 0.139 19.0 111.8-109.2 23.3 36.1 24.7 69.9 14 16 A W H > S+ 0 0 23 -6,-0.3 4,-2.6 2,-0.2 5,-0.2 0.920 83.4 47.5 -60.7 -43.4 34.1 22.6 72.4 15 17 A A H > S+ 0 0 61 -3,-0.2 4,-2.7 2,-0.2 5,-0.2 0.947 114.0 45.4 -62.9 -50.6 30.8 24.1 71.4 16 18 A A H > S+ 0 0 58 -4,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.911 115.5 48.3 -58.8 -43.5 31.3 23.7 67.6 17 19 A I H X S+ 0 0 33 -4,-2.6 4,-1.7 2,-0.2 -1,-0.2 0.916 113.1 47.2 -62.3 -46.4 32.6 20.1 68.1 18 20 A Y H X S+ 0 0 11 -4,-2.6 4,-1.9 -5,-0.2 -2,-0.2 0.881 111.6 50.7 -64.3 -39.5 29.6 19.3 70.4 19 21 A Q H X S+ 0 0 90 -4,-2.7 4,-2.3 2,-0.2 -1,-0.2 0.854 104.4 57.6 -69.5 -32.4 27.1 20.9 67.9 20 22 A D H X S+ 0 0 83 -4,-1.9 4,-2.4 -5,-0.2 -1,-0.2 0.931 106.8 49.8 -60.3 -44.0 28.7 18.8 65.1 21 23 A I H X S+ 0 0 4 -4,-1.7 4,-1.5 1,-0.2 -2,-0.2 0.924 109.5 50.4 -60.6 -44.9 27.8 15.7 67.1 22 24 A R H < S+ 0 0 132 -4,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.897 112.9 47.3 -60.7 -39.0 24.2 16.9 67.6 23 25 A H H < S+ 0 0 167 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.864 115.8 43.3 -70.8 -36.8 23.9 17.5 63.9 24 26 A E H < S+ 0 0 117 -4,-2.4 -1,-0.2 -5,-0.2 -2,-0.2 0.584 88.9 119.7 -85.8 -10.0 25.4 14.2 62.9 25 27 A A S < S- 0 0 25 -4,-1.5 228,-0.1 -5,-0.2 224,-0.1 -0.215 72.4 -96.6 -60.1 144.6 23.4 12.2 65.5 26 28 A S - 0 0 38 223,-0.3 2,-0.5 229,-0.1 -1,-0.1 -0.194 28.8-154.1 -58.7 147.8 21.0 9.4 64.4 27 29 A D + 0 0 153 229,-0.1 -1,-0.1 23,-0.0 226,-0.1 -0.959 24.1 164.7-129.5 107.0 17.3 10.2 64.0 28 30 A F - 0 0 81 -2,-0.5 228,-0.1 1,-0.0 226,-0.0 -0.899 41.1 -88.3-121.5 155.6 15.1 7.2 64.4 29 31 A P - 0 0 54 0, 0.0 22,-2.8 0, 0.0 23,-0.4 -0.236 24.7-170.8 -65.9 152.4 11.3 6.9 65.0 30 32 A C > + 0 0 19 20,-0.3 4,-1.6 21,-0.1 20,-0.1 -0.362 33.6 143.8-129.6 47.4 9.9 6.9 68.5 31 33 A R T 4 + 0 0 174 1,-0.2 4,-0.4 2,-0.2 3,-0.2 0.899 69.7 49.6 -61.1 -42.4 6.3 6.0 67.5 32 34 A V T >4 S+ 0 0 31 1,-0.2 3,-1.5 2,-0.2 -1,-0.2 0.940 109.5 53.4 -63.3 -41.9 5.5 3.8 70.5 33 35 A A T 34 S+ 0 0 1 16,-0.4 -1,-0.2 1,-0.3 -2,-0.2 0.825 108.8 50.6 -58.6 -35.5 6.7 6.5 72.8 34 36 A K T 3< S+ 0 0 116 -4,-1.6 -1,-0.3 -3,-0.2 -2,-0.2 0.389 77.6 120.9 -87.5 1.5 4.4 9.1 71.2 35 37 A L S X S- 0 0 69 -3,-1.5 3,-2.4 -4,-0.4 4,-0.4 -0.437 72.8-121.0 -64.3 138.3 1.2 7.1 71.3 36 38 A P G > S+ 0 0 118 0, 0.0 3,-1.4 0, 0.0 4,-0.3 0.855 111.6 59.9 -49.2 -39.2 -1.5 9.0 73.3 37 39 A K G 3 S+ 0 0 126 1,-0.2 3,-0.2 2,-0.1 -2,-0.1 0.660 103.9 51.7 -67.3 -13.1 -1.8 6.2 75.8 38 40 A N G X S+ 0 0 0 -3,-2.4 3,-1.9 -6,-0.2 4,-0.3 0.387 76.5 102.2-102.5 3.4 1.9 6.5 76.7 39 41 A K G X S+ 0 0 173 -3,-1.4 3,-1.1 -4,-0.4 -1,-0.1 0.863 82.9 47.8 -55.0 -41.2 1.9 10.2 77.4 40 42 A N G 3 S+ 0 0 101 -4,-0.3 -1,-0.3 1,-0.2 48,-0.2 0.367 102.0 64.8 -84.1 5.1 1.8 9.8 81.2 41 43 A R G < S+ 0 0 23 -3,-1.9 25,-0.5 -8,-0.1 2,-0.5 0.367 92.0 78.3-101.4 -1.7 4.7 7.2 81.0 42 44 A N < - 0 0 19 -3,-1.1 3,-0.1 -4,-0.3 6,-0.1 -0.946 59.9-164.3-113.2 127.0 7.0 9.9 79.7 43 45 A R S S+ 0 0 50 -2,-0.5 2,-0.4 1,-0.2 -1,-0.1 0.876 83.8 29.9 -73.9 -38.8 8.6 12.5 82.1 44 46 A Y > - 0 0 72 3,-0.4 3,-1.7 1,-0.1 -1,-0.2 -0.983 69.0-144.4-127.8 132.2 9.6 14.8 79.2 45 47 A R T 3 S+ 0 0 212 -2,-0.4 -1,-0.1 1,-0.3 -2,-0.0 0.734 101.6 48.3 -63.2 -24.1 7.8 15.3 75.9 46 48 A D T 3 S+ 0 0 116 1,-0.1 2,-0.5 2,-0.0 -1,-0.3 0.255 98.3 73.8-102.5 11.2 11.0 15.8 74.0 47 49 A V < + 0 0 12 -3,-1.7 -3,-0.4 2,-0.0 -4,-0.1 -0.909 61.0 152.1-127.1 104.9 13.0 12.8 75.4 48 50 A S - 0 0 4 -2,-0.5 208,-0.5 -6,-0.1 2,-0.2 -0.954 44.5-111.7-132.9 150.7 11.8 9.5 74.0 49 51 A P - 0 0 0 0, 0.0 -16,-0.4 0, 0.0 206,-0.1 -0.587 39.1-110.9 -78.3 142.3 13.4 6.0 73.4 50 52 A F >> - 0 0 2 204,-0.5 4,-1.0 -2,-0.2 3,-0.6 -0.459 24.7-123.8 -67.9 145.3 13.8 5.0 69.7 51 53 A D G >4 S+ 0 0 37 -22,-2.8 3,-0.7 1,-0.2 -1,-0.1 0.909 107.0 56.7 -57.2 -44.1 11.4 2.1 68.8 52 54 A H G 34 S+ 0 0 109 -23,-0.4 -1,-0.2 1,-0.2 -22,-0.1 0.777 117.9 30.4 -63.8 -27.4 14.2 -0.1 67.6 53 55 A S G <4 S+ 0 0 10 -3,-0.6 16,-3.0 201,-0.1 -1,-0.2 0.375 88.4 126.4-114.4 5.2 16.2 -0.0 70.9 54 56 A R E << -A 68 0A 33 -4,-1.0 2,-0.5 -3,-0.7 14,-0.2 -0.236 62.7-116.5 -66.3 151.5 13.4 0.4 73.5 55 57 A I E - 0 0 7 12,-1.9 10,-0.5 10,-0.3 2,-0.5 -0.780 28.2-147.3 -87.5 125.5 13.1 -2.0 76.4 56 58 A K E -A 64 0A 118 -2,-0.5 2,-0.2 8,-0.1 8,-0.2 -0.846 8.1-134.8 -98.2 128.7 9.8 -3.9 76.2 57 59 A L - 0 0 5 6,-2.5 39,-0.1 -2,-0.5 35,-0.0 -0.533 20.7-122.9 -75.2 148.9 8.1 -4.8 79.5 58 60 A H S S+ 0 0 123 -2,-0.2 2,-0.4 37,-0.1 -1,-0.1 0.195 76.7 110.4 -80.9 17.6 6.9 -8.4 79.5 59 61 A Q - 0 0 44 3,-0.2 -2,-0.1 1,-0.1 77,-0.0 -0.792 61.9-146.0 -97.5 137.7 3.2 -7.4 80.3 60 62 A E S S+ 0 0 189 -2,-0.4 3,-0.3 1,-0.1 -1,-0.1 0.819 90.9 65.2 -67.5 -35.7 0.5 -7.8 77.6 61 63 A D S S- 0 0 140 1,-0.2 2,-0.4 2,-0.0 -1,-0.1 0.980 126.8 -17.2 -51.7 -70.3 -1.5 -4.8 78.6 62 64 A N - 0 0 15 1,-0.0 -1,-0.2 2,-0.0 -3,-0.2 -0.930 55.6-170.7-144.4 114.6 1.1 -2.1 77.8 63 65 A D + 0 0 46 -2,-0.4 -6,-2.5 -3,-0.3 2,-0.3 0.320 46.7 124.2 -90.0 11.0 4.8 -3.0 77.3 64 66 A Y E +A 56 0A 0 -8,-0.2 2,-0.3 -32,-0.1 -8,-0.1 -0.553 22.7 154.2 -84.4 129.9 6.0 0.6 77.1 65 67 A I E - 0 0 9 -10,-0.5 2,-2.1 -2,-0.3 -10,-0.3 -0.987 50.3-114.5-144.3 141.7 8.7 2.2 79.4 66 68 A N E S+ 0 0 0 -25,-0.5 17,-1.5 -2,-0.3 2,-0.3 -0.554 77.0 115.8 -79.5 82.6 10.9 5.2 78.6 67 69 A A E - B 0 82A 0 -2,-2.1 -12,-1.9 15,-0.2 2,-0.4 -0.987 47.4-156.0-151.7 144.4 14.1 3.1 78.6 68 70 A S E -AB 54 81A 0 13,-2.6 13,-2.3 -2,-0.3 2,-0.7 -0.961 16.8-130.9-129.7 143.1 16.7 2.2 75.9 69 71 A L E - B 0 80A 52 -16,-3.0 2,-0.9 -2,-0.4 11,-0.2 -0.816 18.9-163.9 -92.9 113.8 19.1 -0.7 75.4 70 72 A I E - B 0 79A 0 9,-3.3 9,-1.9 -2,-0.7 2,-0.8 -0.863 10.0-171.0 -97.0 104.4 22.6 0.8 74.5 71 73 A K E - B 0 78A 127 -2,-0.9 2,-1.1 7,-0.2 7,-0.2 -0.855 7.9-165.7-103.0 106.4 24.4 -2.2 73.1 72 74 A M E >> - B 0 77A 11 5,-2.3 5,-1.6 -2,-0.8 4,-1.3 -0.772 4.9-172.5 -96.5 96.6 28.1 -1.5 72.6 73 75 A E T 45S+ 0 0 172 -2,-1.1 3,-0.4 2,-0.2 -1,-0.2 0.920 79.3 40.8 -52.3 -59.7 29.3 -4.4 70.4 74 76 A E T 45S+ 0 0 98 1,-0.2 -1,-0.2 2,-0.1 -2,-0.1 0.925 118.0 46.6 -62.9 -43.7 33.1 -3.7 70.3 75 77 A A T 45S- 0 0 6 2,-0.1 -1,-0.2 1,-0.0 -2,-0.2 0.685 103.5-135.7 -70.4 -17.5 33.3 -2.8 74.1 76 78 A Q T <5 + 0 0 138 -4,-1.3 2,-0.3 -3,-0.4 -3,-0.2 0.900 63.5 112.2 63.0 44.2 31.2 -5.9 74.9 77 79 A R E < -B 72 0A 45 -5,-1.6 -5,-2.3 2,-0.0 2,-0.3 -0.995 46.6-161.4-147.9 139.8 28.9 -4.1 77.3 78 80 A S E -B 71 0A 34 -2,-0.3 131,-0.7 -7,-0.2 2,-0.3 -0.909 8.0-174.2-118.8 150.0 25.2 -3.2 77.3 79 81 A Y E -Bc 70 209A 0 -9,-1.9 -9,-3.3 -2,-0.3 2,-0.6 -0.974 20.9-137.2-139.2 149.9 23.5 -0.6 79.5 80 82 A I E -Bc 69 210A 0 129,-2.8 131,-3.3 -2,-0.3 2,-0.5 -0.955 20.9-163.0-107.9 123.9 19.9 0.3 79.9 81 83 A L E +Bc 68 211A 0 -13,-2.3 -13,-2.6 -2,-0.6 2,-0.3 -0.932 19.4 163.8-107.7 131.7 19.4 4.1 80.0 82 84 A T E -Bc 67 212A 2 129,-2.1 131,-0.7 -2,-0.5 -15,-0.2 -0.941 37.6-100.2-144.2 162.0 16.1 5.4 81.4 83 85 A Q - 0 0 6 -17,-1.5 132,-0.2 -2,-0.3 131,-0.2 -0.328 55.9 -84.2 -74.4 163.9 14.4 8.5 82.8 84 86 A G - 0 0 0 130,-2.7 -1,-0.1 34,-0.3 -41,-0.1 -0.594 64.1-100.3 -66.6 131.1 13.9 8.9 86.5 85 87 A P - 0 0 3 0, 0.0 35,-2.8 0, 0.0 5,-0.1 -0.132 32.5-132.2 -55.5 149.1 10.7 6.9 87.1 86 88 A L >> - 0 0 24 33,-0.2 3,-2.0 -45,-0.1 4,-0.6 -0.582 32.7 -97.2 -96.7 162.8 7.4 8.8 87.5 87 89 A P T 34 S+ 0 0 109 0, 0.0 3,-0.4 0, 0.0 4,-0.2 0.843 127.6 43.0 -49.5 -35.5 4.9 8.1 90.4 88 90 A N T 34 S+ 0 0 71 -48,-0.2 4,-0.2 1,-0.2 -48,-0.0 0.445 112.6 51.7 -93.6 -1.7 3.0 5.9 88.0 89 91 A T T <> S+ 0 0 6 -3,-2.0 4,-2.3 2,-0.1 -1,-0.2 0.256 74.9 96.6-118.2 14.3 6.0 4.1 86.4 90 92 A C H X S+ 0 0 11 -4,-0.6 4,-2.1 -3,-0.4 5,-0.2 0.884 87.4 51.0 -68.5 -35.8 7.9 2.9 89.5 91 93 A G H > S+ 0 0 4 1,-0.2 4,-2.2 -4,-0.2 -1,-0.2 0.953 111.1 48.8 -62.8 -47.2 6.3 -0.5 89.2 92 94 A H H > S+ 0 0 11 -4,-0.2 4,-2.2 1,-0.2 -2,-0.2 0.868 107.5 56.1 -58.0 -42.3 7.3 -0.6 85.5 93 95 A F H X S+ 0 0 1 -4,-2.3 4,-2.3 1,-0.2 -1,-0.2 0.940 111.9 40.9 -57.5 -50.7 10.8 0.4 86.4 94 96 A W H X S+ 0 0 0 -4,-2.1 4,-2.6 2,-0.2 -1,-0.2 0.813 110.5 57.6 -70.4 -29.1 11.2 -2.6 88.8 95 97 A E H X S+ 0 0 15 -4,-2.2 4,-3.1 2,-0.2 5,-0.2 0.894 109.2 47.2 -65.0 -37.8 9.4 -4.9 86.4 96 98 A M H X S+ 0 0 0 -4,-2.2 4,-3.0 2,-0.2 6,-0.3 0.948 109.6 51.9 -68.1 -47.1 12.1 -4.0 83.9 97 99 A V H <>S+ 0 0 1 -4,-2.3 5,-1.6 1,-0.2 4,-0.5 0.924 115.6 43.3 -54.3 -45.2 14.9 -4.5 86.4 98 100 A W H ><5S+ 0 0 27 -4,-2.6 3,-1.5 2,-0.2 -2,-0.2 0.978 115.0 45.7 -65.6 -57.1 13.5 -7.9 87.1 99 101 A E H 3<5S+ 0 0 32 -4,-3.1 -2,-0.2 1,-0.3 -3,-0.2 0.883 116.2 46.4 -57.5 -37.5 12.7 -9.0 83.5 100 102 A Q T 3<5S- 0 0 51 -4,-3.0 -1,-0.3 -5,-0.2 -2,-0.2 0.506 105.6-129.6 -84.3 -2.1 16.2 -7.8 82.3 101 103 A K T < 5 + 0 0 127 -3,-1.5 106,-2.5 -4,-0.5 -3,-0.2 0.793 41.3 175.5 61.6 30.8 17.9 -9.5 85.2 102 104 A S < - 0 0 4 -5,-1.6 -1,-0.2 -6,-0.3 107,-0.1 -0.351 22.0-169.1 -66.7 149.7 19.9 -6.3 86.1 103 105 A R + 0 0 56 104,-0.5 67,-2.7 98,-0.4 2,-0.3 0.540 67.9 41.6-114.2 -17.2 22.0 -6.5 89.2 104 106 A G E -d 170 0A 0 97,-0.3 106,-2.1 65,-0.2 2,-0.4 -0.965 56.7-161.2-135.4 149.6 22.9 -2.8 89.6 105 107 A V E -de 171 210A 0 65,-2.7 67,-3.1 -2,-0.3 2,-0.6 -0.997 11.0-157.1-129.3 124.7 21.1 0.5 89.2 106 108 A V E -de 172 211A 0 104,-3.3 106,-2.6 -2,-0.4 2,-0.5 -0.925 8.7-171.7-106.6 116.4 23.1 3.7 88.8 107 109 A M E +de 173 212A 0 65,-2.8 67,-2.9 -2,-0.6 106,-0.2 -0.946 9.9 177.5-109.6 122.1 21.3 6.9 89.8 108 110 A L + 0 0 0 104,-2.5 2,-0.2 -2,-0.5 69,-0.2 0.273 60.4 53.8-108.7 12.5 23.1 10.2 88.9 109 111 A N S S- 0 0 2 103,-0.2 2,-0.3 104,-0.1 67,-0.1 -0.757 76.7-113.8-133.6 177.4 20.6 12.7 90.1 110 112 A R - 0 0 110 -2,-0.2 8,-0.2 67,-0.1 3,-0.1 -0.804 28.9-115.4-113.0 159.4 18.6 13.6 93.3 111 113 A V S S+ 0 0 34 -2,-0.3 7,-3.2 1,-0.2 8,-1.1 0.895 108.1 28.7 -60.0 -40.6 14.8 13.3 93.6 112 114 A M E S-I 117 0B 101 5,-0.2 2,-0.4 6,-0.2 5,-0.2 -0.988 71.8-179.5-125.6 128.7 14.7 17.1 94.1 113 115 A E E > S-I 116 0B 8 3,-2.5 3,-1.4 -2,-0.4 -4,-0.0 -0.989 71.1 -18.7-132.3 120.8 17.2 19.5 92.5 114 116 A K T 3 S- 0 0 188 -2,-0.4 -1,-0.1 1,-0.3 3,-0.1 0.886 130.0 -46.2 49.8 48.7 17.1 23.2 93.0 115 117 A G T 3 S+ 0 0 65 1,-0.2 2,-0.4 -3,-0.0 -1,-0.3 0.506 118.1 103.8 78.9 4.7 13.4 23.2 94.1 116 118 A S E < S-I 113 0B 63 -3,-1.4 -3,-2.5 0, 0.0 2,-0.2 -0.966 71.2-121.3-124.5 136.5 12.2 20.9 91.3 117 119 A L E +I 112 0B 116 -2,-0.4 -5,-0.2 -5,-0.2 -6,-0.1 -0.537 32.4 169.5 -71.5 135.9 11.2 17.2 91.4 118 120 A K + 0 0 22 -7,-3.2 -34,-0.3 1,-0.4 2,-0.3 0.445 64.3 10.5-121.8 -9.0 13.4 15.3 88.9 119 121 A C S S- 0 0 2 -8,-1.1 -1,-0.4 -36,-0.1 -33,-0.2 -0.945 75.4-107.0-171.1 143.4 12.5 11.7 89.8 120 122 A A - 0 0 16 -35,-2.8 2,-1.7 -2,-0.3 3,-0.1 -0.395 42.2-103.1 -75.1 157.2 10.0 9.7 92.0 121 123 A Q + 0 0 58 1,-0.2 -1,-0.1 -2,-0.1 4,-0.1 -0.656 53.4 167.6 -79.1 86.1 11.2 8.1 95.3 122 124 A Y + 0 0 0 -2,-1.7 -1,-0.2 -37,-0.1 -28,-0.1 0.446 53.1 50.1 -89.1 -0.0 11.2 4.6 93.7 123 125 A W S S- 0 0 8 -3,-0.1 2,-0.3 7,-0.0 18,-0.1 -0.918 94.6 -92.0-132.9 156.9 13.2 2.8 96.5 124 126 A P - 0 0 4 0, 0.0 6,-0.1 0, 0.0 3,-0.1 -0.512 22.3-164.2 -72.4 130.5 12.6 2.6 100.3 125 127 A Q S S+ 0 0 123 -2,-0.3 2,-0.4 4,-0.2 5,-0.1 0.637 78.6 51.2 -86.2 -15.8 14.5 5.2 102.4 126 128 A K S > S- 0 0 90 3,-0.4 3,-1.6 1,-0.1 16,-0.3 -0.987 72.9-141.0-130.0 132.5 13.8 3.1 105.5 127 129 A E T 3 S+ 0 0 89 -2,-0.4 15,-0.2 1,-0.3 3,-0.2 0.886 103.8 53.5 -50.4 -47.3 14.3 -0.5 106.3 128 130 A E T 3 S+ 0 0 134 1,-0.2 2,-0.4 13,-0.1 -1,-0.3 0.526 103.0 61.1 -71.0 -8.5 11.0 -0.8 108.2 129 131 A K S < S- 0 0 130 -3,-1.6 -3,-0.4 13,-0.1 -1,-0.2 -0.695 71.8-179.6-123.1 79.0 8.9 0.6 105.4 130 132 A E - 0 0 98 -2,-0.4 2,-0.4 -3,-0.2 11,-0.2 -0.176 23.0-120.6 -70.9 170.2 9.3 -1.6 102.4 131 133 A M E -F 140 0A 50 9,-2.8 9,-2.7 -7,-0.1 2,-0.5 -0.919 16.4-160.9-118.8 142.2 7.5 -0.9 99.1 132 134 A I E -F 139 0A 77 -2,-0.4 2,-0.9 7,-0.2 7,-0.2 -0.986 6.3-158.2-120.8 130.1 5.0 -2.9 97.2 133 135 A F E >>> -F 138 0A 15 5,-2.7 5,-1.3 -2,-0.5 4,-1.0 -0.847 13.1-173.3-107.8 90.3 4.3 -2.3 93.6 134 136 A E G >45S+ 0 0 168 -2,-0.9 3,-0.5 1,-0.2 -1,-0.2 0.848 77.5 56.7 -53.9 -45.6 0.8 -3.8 93.2 135 137 A D G 345S+ 0 0 105 1,-0.2 -1,-0.2 -3,-0.1 -2,-0.0 0.830 119.7 31.8 -60.2 -31.9 0.5 -3.5 89.5 136 138 A T G <45S- 0 0 22 -3,-0.8 -1,-0.2 2,-0.1 -2,-0.2 0.440 103.2-125.8-107.3 1.8 3.7 -5.5 88.9 137 139 A N T <<5 + 0 0 65 -4,-1.0 24,-1.9 -3,-0.5 25,-0.6 0.897 62.0 134.8 56.5 47.7 3.5 -7.8 91.9 138 140 A L E < -FG 133 160A 6 -5,-1.3 -5,-2.7 22,-0.2 2,-0.4 -0.955 41.7-154.7-128.0 145.1 7.0 -6.9 93.3 139 141 A K E -FG 132 159A 62 20,-2.4 20,-3.2 -2,-0.4 2,-0.4 -0.943 10.1-166.2-118.1 141.1 8.2 -6.1 96.8 140 142 A L E -FG 131 158A 0 -9,-2.7 -9,-2.8 -2,-0.4 2,-0.4 -0.992 5.4-176.2-132.9 128.9 11.3 -4.0 97.5 141 143 A T E - G 0 157A 31 16,-2.1 16,-2.7 -2,-0.4 2,-0.6 -0.961 26.9-128.6-128.9 139.3 13.1 -3.6 100.8 142 144 A L E + G 0 156A 2 -2,-0.4 14,-0.2 -16,-0.3 3,-0.1 -0.776 27.0 177.2 -82.9 118.8 16.1 -1.5 101.8 143 145 A I E - 0 0 76 12,-3.0 2,-0.3 -2,-0.6 13,-0.2 0.847 59.8 -37.1 -90.7 -43.3 18.6 -3.9 103.5 144 146 A S E - G 0 155A 43 11,-1.4 11,-2.8 -17,-0.0 -1,-0.4 -0.978 51.2-143.2-171.0 168.1 21.4 -1.4 104.2 145 147 A E E - G 0 154A 69 -2,-0.3 2,-0.7 9,-0.2 9,-0.2 -0.999 7.7-150.5-147.7 143.6 23.2 1.6 102.9 146 148 A D E - G 0 153A 83 7,-3.2 7,-2.3 -2,-0.3 2,-0.5 -0.909 24.0-159.0-115.2 100.2 26.7 2.9 102.9 147 149 A I E + G 0 152A 110 -2,-0.7 5,-0.2 5,-0.2 2,-0.2 -0.720 12.9 179.8 -87.3 121.7 26.5 6.7 102.8 148 150 A K - 0 0 39 3,-2.5 148,-0.2 -2,-0.5 147,-0.1 -0.591 44.0 -93.3-111.4 175.1 29.6 8.6 101.6 149 151 A S S S+ 0 0 65 146,-3.2 146,-0.1 1,-0.2 147,-0.1 0.869 119.5 9.1 -59.3 -41.1 30.2 12.3 101.2 150 152 A Y S S+ 0 0 12 1,-0.2 25,-1.9 145,-0.1 26,-1.0 0.420 131.8 31.0-122.3 0.0 29.1 12.6 97.5 151 153 A Y E - H 0 174A 0 23,-0.3 -3,-2.5 144,-0.2 2,-0.4 -0.984 58.6-150.3-153.2 159.9 27.6 9.1 96.8 152 154 A T E -GH 147 173A 9 21,-2.4 21,-3.1 -2,-0.3 2,-0.5 -0.996 5.7-153.7-135.2 137.2 25.7 6.3 98.6 153 155 A V E -GH 146 172A 29 -7,-2.3 -7,-3.2 -2,-0.4 2,-0.4 -0.949 19.1-167.4-112.5 128.8 25.6 2.6 97.8 154 156 A R E -GH 145 171A 24 17,-3.0 17,-2.9 -2,-0.5 2,-0.6 -0.924 20.1-143.2-123.6 145.7 22.5 0.7 98.8 155 157 A Q E -GH 144 170A 74 -11,-2.8 -12,-3.0 -2,-0.4 -11,-1.4 -0.921 28.0-177.8-101.9 116.8 21.6 -3.0 99.1 156 158 A L E -GH 142 169A 1 13,-3.0 13,-2.8 -2,-0.6 2,-0.6 -0.857 20.6-143.7-115.8 148.1 18.1 -3.6 98.1 157 159 A E E -GH 141 168A 69 -16,-2.7 -16,-2.1 -2,-0.3 2,-0.6 -0.960 15.8-166.9-111.6 116.7 16.1 -6.8 98.1 158 160 A L E -GH 140 167A 0 9,-3.1 9,-2.5 -2,-0.6 2,-0.4 -0.918 7.4-168.6-106.9 124.7 13.7 -7.2 95.1 159 161 A E E -GH 139 166A 23 -20,-3.2 -20,-2.4 -2,-0.6 2,-0.9 -0.935 23.8-140.7-119.3 134.6 11.2 -9.9 95.4 160 162 A N E > -G 138 0A 30 5,-2.3 4,-2.7 -2,-0.4 5,-0.4 -0.804 18.7-158.1 -85.8 106.9 8.8 -11.4 92.8 161 163 A L T 4 S+ 0 0 46 -24,-1.9 -1,-0.2 -2,-0.9 -23,-0.1 0.826 86.2 57.5 -59.1 -31.4 5.8 -11.9 95.0 162 164 A T T 4 S+ 0 0 100 -25,-0.6 -1,-0.2 1,-0.2 -24,-0.1 0.968 121.3 21.6 -64.9 -54.6 4.4 -14.5 92.6 163 165 A T T 4 S- 0 0 83 2,-0.1 -2,-0.2 1,-0.0 -1,-0.2 0.657 95.9-128.6 -90.0 -16.4 7.3 -16.9 92.7 164 166 A Q < + 0 0 134 -4,-2.7 -3,-0.1 1,-0.3 2,-0.1 0.461 58.2 145.9 81.3 1.0 8.9 -15.9 96.0 165 167 A E - 0 0 92 -5,-0.4 -5,-2.3 -6,-0.1 2,-0.4 -0.449 31.8-160.2 -69.5 143.6 12.2 -15.5 94.3 166 168 A T E - H 0 159A 64 -7,-0.2 2,-0.4 -2,-0.1 -7,-0.2 -0.946 7.7-167.9-126.0 149.6 14.4 -12.7 95.7 167 169 A R E - H 0 158A 52 -9,-2.5 -9,-3.1 -2,-0.4 2,-0.6 -0.995 22.3-126.9-136.2 142.9 17.3 -10.9 94.3 168 170 A E E - H 0 157A 80 -2,-0.4 2,-0.4 -11,-0.2 -11,-0.2 -0.789 28.3-168.3 -88.5 124.4 19.9 -8.5 95.7 169 171 A I E - H 0 156A 2 -13,-2.8 -13,-3.0 -2,-0.6 2,-0.5 -0.942 11.5-142.7-113.5 134.8 20.0 -5.3 93.7 170 172 A L E -dH 104 155A 17 -67,-2.7 -65,-2.7 -2,-0.4 2,-0.6 -0.838 10.1-157.5 -99.4 133.7 22.8 -2.8 94.3 171 173 A H E -dH 105 154A 0 -17,-2.9 -17,-3.0 -2,-0.5 2,-0.7 -0.948 4.5-167.3-115.5 117.8 22.0 0.9 94.0 172 174 A F E -dH 106 153A 3 -67,-3.1 -65,-2.8 -2,-0.6 2,-0.7 -0.906 11.1-172.0-107.6 104.3 24.8 3.4 93.3 173 175 A H E -dH 107 152A 10 -21,-3.1 -21,-2.4 -2,-0.7 2,-0.8 -0.865 12.7-162.9-107.1 108.3 23.6 6.9 93.9 174 176 A Y E - H 0 151A 0 -67,-2.9 3,-0.4 -2,-0.7 -23,-0.3 -0.795 12.4-178.3 -86.7 113.3 25.8 9.8 92.9 175 177 A T + 0 0 32 -25,-1.9 -24,-0.2 -2,-0.8 -1,-0.1 0.582 65.6 53.9 -95.7 -6.8 24.3 12.7 94.9 176 178 A T + 0 0 62 -26,-1.0 8,-0.2 2,-0.1 -1,-0.2 -0.103 68.9 111.6-122.1 38.0 26.4 15.7 93.9 177 179 A W - 0 0 4 -3,-0.4 -67,-0.1 -69,-0.2 3,-0.1 -0.910 61.6-141.6-110.8 101.5 26.2 15.8 90.1 178 180 A P > - 0 0 60 0, 0.0 3,-1.7 0, 0.0 2,-0.1 -0.255 27.3 -90.8 -63.1 150.8 24.2 18.9 89.2 179 181 A D T 3 S+ 0 0 48 1,-0.3 3,-0.1 39,-0.0 -70,-0.0 -0.353 112.3 6.6 -64.3 138.4 21.7 18.9 86.3 180 182 A F T 3 S+ 0 0 122 1,-0.2 -1,-0.3 -3,-0.1 2,-0.1 0.715 123.0 97.7 58.7 21.8 23.2 20.0 82.9 181 183 A G < - 0 0 16 -3,-1.7 -1,-0.2 -4,-0.1 79,-0.1 -0.410 69.8-110.2-123.5-162.7 26.5 20.0 84.9 182 184 A V - 0 0 37 -2,-0.1 82,-0.1 -3,-0.1 37,-0.0 -0.876 35.6 -87.6-133.5 162.8 29.6 17.9 85.6 183 185 A P - 0 0 5 0, 0.0 -6,-0.1 0, 0.0 -1,-0.1 -0.217 45.4-104.2 -64.8 161.9 31.1 16.0 88.6 184 186 A E S S- 0 0 157 -8,-0.2 3,-0.1 1,-0.2 -7,-0.0 0.866 96.2 -16.8 -56.0 -36.7 33.4 17.9 91.0 185 187 A S > - 0 0 26 1,-0.1 4,-2.6 108,-0.0 5,-0.2 -0.993 62.1-105.8-165.4 160.5 36.3 16.2 89.4 186 188 A P H > S+ 0 0 31 0, 0.0 4,-3.3 0, 0.0 5,-0.3 0.922 122.5 56.0 -56.4 -40.5 37.5 13.4 87.1 187 189 A A H > S+ 0 0 5 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.929 107.2 45.9 -58.0 -47.7 38.8 11.8 90.4 188 190 A S H > S+ 0 0 1 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.929 115.8 47.0 -64.9 -40.1 35.3 11.9 92.0 189 191 A F H X S+ 0 0 0 -4,-2.6 4,-2.5 1,-0.2 -2,-0.2 0.957 115.0 44.8 -63.2 -51.9 33.7 10.5 88.9 190 192 A L H X S+ 0 0 0 -4,-3.3 4,-2.4 1,-0.2 5,-0.2 0.836 106.9 58.7 -63.8 -35.8 36.2 7.7 88.4 191 193 A N H X S+ 0 0 6 -4,-2.4 4,-0.9 -5,-0.3 -1,-0.2 0.948 111.7 42.9 -58.2 -46.6 36.2 6.7 92.1 192 194 A F H >X S+ 0 0 0 -4,-1.6 4,-1.9 -5,-0.2 3,-0.6 0.926 111.6 53.2 -62.8 -51.2 32.4 6.1 91.8 193 195 A L H 3X S+ 0 0 0 -4,-2.5 4,-2.5 1,-0.3 -1,-0.2 0.905 109.1 48.6 -54.9 -45.0 32.6 4.3 88.4 194 196 A F H 3X S+ 0 0 10 -4,-2.4 4,-2.9 1,-0.2 -1,-0.3 0.750 105.6 59.1 -70.3 -19.3 35.2 1.8 89.6 195 197 A K H <>S+ 0 0 0 -4,-1.9 5,-0.8 2,-0.2 3,-0.5 0.956 116.1 47.4 -65.6 -48.9 30.2 0.1 90.3 197 199 A R H ><5S+ 0 0 48 -4,-2.5 3,-1.7 1,-0.2 5,-0.2 0.939 110.5 50.7 -56.6 -51.8 32.7 -2.0 88.3 198 200 A E H 3<5S+ 0 0 126 -4,-2.9 -1,-0.2 1,-0.3 -2,-0.2 0.737 99.2 67.9 -62.2 -21.0 34.3 -3.6 91.4 199 201 A S T <<5S- 0 0 38 -4,-1.1 -1,-0.3 -3,-0.5 -2,-0.2 0.671 107.8-121.3 -72.6 -17.3 30.9 -4.6 92.6 200 202 A G T X 5S+ 0 0 27 -3,-1.7 3,-1.9 -4,-0.5 6,-0.2 0.318 79.0 123.2 91.7 -7.5 30.4 -7.0 89.8 201 203 A S T 3 S+ 0 0 9 40,-0.2 4,-1.7 41,-0.2 41,-0.2 0.991 127.6 18.5 -74.1 -72.5 22.8 14.1 79.9 219 221 A R H > S+ 0 0 1 2,-0.2 4,-2.4 1,-0.2 5,-0.2 0.940 128.0 52.8 -65.2 -46.8 24.4 12.7 83.1 220 222 A S H > S+ 0 0 0 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.886 110.1 49.3 -55.9 -42.1 23.6 9.1 82.2 221 223 A G H > S+ 0 0 0 -4,-0.5 4,-2.4 2,-0.2 -1,-0.2 0.859 109.0 51.6 -66.9 -35.7 25.2 9.6 78.8 222 224 A T H X S+ 0 0 0 -4,-1.7 4,-2.0 2,-0.2 5,-0.2 0.934 111.0 48.9 -65.0 -44.4 28.4 11.1 80.3 223 225 A F H X S+ 0 0 0 -4,-2.4 4,-1.9 1,-0.2 -2,-0.2 0.907 114.4 43.5 -61.0 -47.8 28.7 8.1 82.7 224 226 A C H X S+ 0 0 0 -4,-2.2 4,-3.0 -5,-0.2 5,-0.2 0.888 110.6 54.4 -69.6 -39.3 28.2 5.5 79.9 225 227 A L H X S+ 0 0 0 -4,-2.4 4,-2.8 2,-0.2 5,-0.2 0.931 111.1 45.2 -60.6 -46.4 30.5 7.2 77.4 226 228 A A H X S+ 0 0 0 -4,-2.0 4,-2.3 2,-0.2 5,-0.2 0.952 114.6 48.3 -63.5 -48.4 33.5 7.3 79.8 227 229 A D H X S+ 0 0 0 -4,-1.9 4,-1.7 -5,-0.2 -2,-0.2 0.927 114.0 47.1 -57.3 -45.2 32.9 3.7 81.0 228 230 A T H X S+ 0 0 0 -4,-3.0 4,-2.3 1,-0.2 -2,-0.2 0.942 111.4 49.5 -64.6 -46.5 32.7 2.5 77.3 229 231 A C H X S+ 0 0 0 -4,-2.8 4,-2.3 1,-0.2 -1,-0.2 0.880 110.1 50.6 -60.6 -39.4 35.8 4.4 76.2 230 232 A L H X S+ 0 0 0 -4,-2.3 4,-1.9 -5,-0.2 -1,-0.2 0.880 110.0 51.7 -64.9 -36.2 37.9 3.1 79.1 231 233 A L H X S+ 0 0 30 -4,-1.7 4,-1.6 -5,-0.2 -2,-0.2 0.909 109.9 48.7 -64.9 -44.4 36.7 -0.4 78.2 232 234 A L H X S+ 0 0 7 -4,-2.3 4,-2.4 1,-0.2 -2,-0.2 0.893 108.8 53.6 -66.2 -37.4 37.8 0.1 74.6 233 235 A M H < S+ 0 0 10 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.911 110.2 46.5 -62.7 -41.9 41.2 1.4 75.6 234 236 A D H < S+ 0 0 105 -4,-1.9 -1,-0.2 -5,-0.2 -2,-0.2 0.807 116.6 47.9 -68.6 -29.3 41.8 -1.7 77.7 235 237 A K H < S+ 0 0 91 -4,-1.6 -2,-0.2 -5,-0.2 -3,-0.2 0.990 98.6 68.0 -76.1 -65.4 40.6 -3.9 74.8 236 238 A R S < S- 0 0 74 -4,-2.4 6,-0.0 1,-0.1 0, 0.0 0.071 82.5-118.6 -55.6 165.6 42.4 -2.6 71.7 237 239 A K S S+ 0 0 204 1,-0.3 -1,-0.1 2,-0.1 -4,-0.1 0.499 107.4 36.2 -83.2 -6.9 46.2 -2.9 71.0 238 240 A D > - 0 0 87 1,-0.1 3,-3.1 -5,-0.0 -1,-0.3 -0.603 63.4-169.3-151.5 87.1 46.5 0.9 70.9 239 241 A P G > S+ 0 0 26 0, 0.0 3,-1.5 0, 0.0 -5,-0.1 0.680 85.7 71.2 -45.7 -27.4 44.3 3.0 73.4 240 242 A S G 3 S+ 0 0 72 1,-0.3 -7,-0.0 -7,-0.1 -2,-0.0 0.742 85.2 71.6 -65.2 -21.0 45.2 6.2 71.5 241 243 A S G < + 0 0 50 -3,-3.1 2,-0.3 -8,-0.1 -1,-0.3 0.719 69.3 111.5 -67.4 -22.9 43.0 4.9 68.8 242 244 A V < - 0 0 4 -3,-1.5 2,-0.8 -4,-0.2 3,-0.1 -0.396 52.9-161.4 -63.0 118.6 39.8 5.5 70.8 243 245 A D > - 0 0 45 -2,-0.3 4,-2.2 1,-0.2 3,-0.4 -0.865 2.6-166.2-101.7 100.0 37.8 8.3 69.2 244 246 A I H > S+ 0 0 0 -2,-0.8 4,-2.3 1,-0.2 -1,-0.2 0.846 87.5 54.7 -59.1 -34.6 35.4 9.6 71.9 245 247 A K H > S+ 0 0 47 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.882 108.7 48.3 -67.8 -35.5 33.3 11.5 69.4 246 248 A K H > S+ 0 0 148 -3,-0.4 4,-2.0 2,-0.2 -2,-0.2 0.899 111.0 51.0 -70.2 -37.4 32.8 8.3 67.3 247 249 A V H X S+ 0 0 10 -4,-2.2 4,-2.5 2,-0.2 -2,-0.2 0.902 109.4 50.0 -65.2 -41.8 31.9 6.4 70.4 248 250 A L H X S+ 0 0 0 -4,-2.3 4,-2.6 2,-0.2 -2,-0.2 0.928 110.1 49.9 -64.0 -43.9 29.3 9.0 71.4 249 251 A L H < S+ 0 0 40 -4,-2.1 -223,-0.3 2,-0.2 4,-0.3 0.878 110.4 52.0 -61.3 -36.0 27.8 9.0 67.9 250 252 A E H >< S+ 0 0 62 -4,-2.0 3,-1.5 1,-0.2 4,-0.4 0.937 110.6 47.0 -65.6 -45.2 27.6 5.2 68.1 251 253 A M H >X S+ 0 0 0 -4,-2.5 3,-2.0 1,-0.3 4,-1.0 0.894 103.5 63.0 -63.4 -37.7 25.8 5.4 71.5 252 254 A R T 3< S+ 0 0 10 -4,-2.6 -1,-0.3 1,-0.3 -2,-0.2 0.554 87.4 72.1 -66.4 -4.5 23.5 8.0 70.1 253 255 A K T <4 S+ 0 0 87 -3,-1.5 -1,-0.3 -4,-0.3 -2,-0.2 0.760 104.6 40.3 -75.9 -23.2 22.2 5.3 67.6 254 256 A F T <4 S+ 0 0 36 -3,-2.0 -204,-0.5 -4,-0.4 2,-0.3 0.675 129.4 11.9 -97.9 -25.8 20.5 3.7 70.7 255 257 A R S >< S- 0 0 0 -4,-1.0 3,-0.7 -206,-0.1 -1,-0.3 -0.949 78.6-113.7-155.5 138.1 19.2 6.7 72.5 256 258 A M T 3 S+ 0 0 50 -208,-0.5 -3,-0.1 -2,-0.3 -229,-0.1 -0.267 86.5 13.3 -70.2 155.8 18.8 10.4 71.6 257 259 A G T 3 + 0 0 12 1,-0.2 2,-0.2 -5,-0.1 -1,-0.2 0.572 67.2 175.4 58.5 23.9 20.7 13.3 73.3 258 260 A L < + 0 0 0 -3,-0.7 -40,-0.2 -10,-0.1 -1,-0.2 -0.428 67.6 23.8 -64.5 123.9 23.4 11.4 75.2 259 261 A I S S- 0 0 0 -42,-2.4 -41,-0.2 -2,-0.2 -40,-0.1 0.743 73.7-158.0 82.5 108.1 25.7 14.2 76.7 260 262 A Q + 0 0 60 -79,-0.1 2,-0.3 1,-0.0 -42,-0.1 0.509 63.6 36.8-100.0 -6.5 23.7 17.4 77.0 261 263 A T S >> S- 0 0 34 -43,-0.1 4,-1.4 -80,-0.1 3,-0.6 -0.973 75.6-118.6-141.3 157.6 26.3 20.2 77.1 262 264 A A H 3> S+ 0 0 26 -2,-0.3 4,-2.4 1,-0.2 5,-0.1 0.852 116.0 56.3 -62.4 -31.7 29.7 20.9 75.5 263 265 A D H 3> S+ 0 0 82 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.752 100.9 54.0 -73.4 -26.1 31.2 20.8 78.9 264 266 A Q H <> S+ 0 0 1 -3,-0.6 4,-2.0 2,-0.2 -1,-0.2 0.843 110.5 50.1 -73.1 -30.9 29.9 17.3 79.8 265 267 A L H X S+ 0 0 0 -4,-1.4 4,-1.7 2,-0.2 -2,-0.2 0.944 111.8 46.0 -67.7 -47.2 31.7 16.3 76.5 266 268 A R H X S+ 0 0 69 -4,-2.4 4,-1.8 1,-0.2 -2,-0.2 0.914 111.6 52.8 -62.0 -40.6 34.9 18.0 77.6 267 269 A F H X S+ 0 0 10 -4,-2.4 4,-2.6 1,-0.2 -1,-0.2 0.891 103.7 57.0 -61.8 -38.4 34.5 16.4 81.0 268 270 A S H X S+ 0 0 0 -4,-2.0 4,-2.3 1,-0.2 -1,-0.2 0.881 104.8 52.1 -58.5 -40.7 34.2 13.0 79.3 269 271 A Y H X S+ 0 0 0 -4,-1.7 4,-2.6 2,-0.2 -1,-0.2 0.934 111.4 46.5 -60.5 -45.9 37.6 13.6 77.7 270 272 A L H X S+ 0 0 53 -4,-1.8 4,-2.3 1,-0.2 5,-0.2 0.866 111.0 52.2 -64.8 -39.4 39.2 14.4 81.1 271 273 A A H X S+ 0 0 0 -4,-2.6 4,-2.8 2,-0.2 -1,-0.2 0.918 113.4 43.0 -63.7 -43.9 37.6 11.4 82.7 272 274 A V H X S+ 0 0 0 -4,-2.3 4,-2.5 2,-0.2 -2,-0.2 0.932 113.7 50.7 -69.7 -44.1 38.9 9.0 80.0 273 275 A I H X S+ 0 0 29 -4,-2.6 4,-0.6 2,-0.2 -2,-0.2 0.893 115.7 43.2 -59.7 -40.9 42.4 10.6 79.9 274 276 A E H >< S+ 0 0 46 -4,-2.3 3,-1.2 1,-0.2 4,-0.5 0.948 114.9 48.3 -71.2 -48.4 42.6 10.3 83.7 275 277 A G H >X S+ 0 0 0 -4,-2.8 4,-1.5 1,-0.3 3,-1.2 0.808 96.7 72.1 -62.6 -30.2 41.2 6.8 83.9 276 278 A A H 3X S+ 0 0 17 -4,-2.5 4,-2.8 1,-0.3 -1,-0.3 0.849 85.6 68.2 -53.2 -35.8 43.5 5.7 81.1 277 279 A K H <<>S+ 0 0 77 -3,-1.2 5,-1.0 -4,-0.6 -1,-0.3 0.885 102.2 44.8 -52.1 -42.7 46.4 5.9 83.7 278 280 A F H X45S+ 0 0 69 -3,-1.2 3,-1.4 -4,-0.5 -1,-0.2 0.895 111.6 52.6 -69.4 -40.1 44.9 3.0 85.6 279 281 A I H 3<5S+ 0 0 24 -4,-1.5 -2,-0.2 1,-0.3 -1,-0.2 0.875 105.9 54.2 -63.0 -38.5 44.3 1.0 82.4 280 282 A M T 3<5S- 0 0 130 -4,-2.8 -1,-0.3 -5,-0.2 -2,-0.2 0.416 131.9 -89.6 -76.9 2.3 47.9 1.5 81.3 281 283 A G T < 5S+ 0 0 53 -3,-1.4 -3,-0.2 1,-0.3 -4,-0.1 -0.164 73.1 147.7 123.0 -44.3 49.1 0.0 84.6 282 284 A D < - 0 0 62 -5,-1.0 -1,-0.3 1,-0.2 4,-0.3 0.029 21.4-175.2 -33.5 114.2 49.4 2.8 87.2 283 285 A S S S+ 0 0 108 1,-0.2 4,-0.3 2,-0.1 -1,-0.2 0.338 75.8 60.8 -99.3 5.5 48.5 1.2 90.5 284 286 A S S > S+ 0 0 68 2,-0.1 4,-1.5 1,-0.1 -1,-0.2 0.525 84.0 77.6-106.1 -11.9 48.7 4.5 92.5 285 287 A V H > S+ 0 0 0 2,-0.2 4,-3.0 1,-0.2 5,-0.2 0.864 86.9 57.6 -68.6 -37.1 46.0 6.5 90.7 286 288 A Q H > S+ 0 0 47 -4,-0.3 4,-2.5 2,-0.2 -1,-0.2 0.957 109.5 42.6 -60.6 -52.5 43.0 4.8 92.3 287 289 A D H > S+ 0 0 104 -4,-0.3 4,-3.3 1,-0.2 5,-0.3 0.911 113.0 56.2 -59.2 -40.3 43.9 5.7 95.9 288 290 A Q H X S+ 0 0 70 -4,-1.5 4,-3.1 1,-0.2 -2,-0.2 0.953 107.6 48.1 -53.3 -52.2 44.8 9.1 94.5 289 291 A W H X S+ 0 0 0 -4,-3.0 4,-1.7 2,-0.2 -2,-0.2 0.896 111.8 49.1 -56.6 -45.7 41.3 9.4 93.1 290 292 A K H X>S+ 0 0 83 -4,-2.5 4,-1.1 2,-0.2 5,-0.8 0.955 112.8 46.8 -61.4 -49.2 39.8 8.3 96.4 291 293 A E H ><5S+ 0 0 156 -4,-3.3 3,-0.8 1,-0.2 -2,-0.2 0.927 113.7 49.5 -57.3 -45.4 41.9 10.8 98.4 292 294 A L H 3<5S+ 0 0 104 -4,-3.1 -1,-0.2 -5,-0.3 -2,-0.2 0.785 107.7 54.5 -65.5 -26.7 41.0 13.5 95.8 293 295 A S H 3<5S- 0 0 3 -4,-1.7 -1,-0.2 -3,-0.3 -2,-0.2 0.667 90.3-148.0 -83.3 -15.0 37.3 12.7 96.1 294 296 A H T <<5 + 0 0 145 -4,-1.1 -3,-0.1 -3,-0.8 -2,-0.1 0.926 27.4 172.7 47.9 51.8 37.2 13.1 99.9 295 297 A E < 0 0 12 -5,-0.8 -146,-3.2 -146,-0.1 -144,-0.2 0.720 360.0 360.0 -65.6 -16.9 34.5 10.4 100.1 296 298 A D 0 0 146 -148,-0.2 -148,-0.1 -147,-0.1 0, 0.0 -0.447 360.0 360.0 -93.6 360.0 34.7 10.4 103.9