==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=29-APR-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 24-JAN-12 3VOG . COMPND 2 MOLECULE: CELLOBIOHYDROLASE; . SOURCE 2 ORGANISM_SCIENTIFIC: COPRINOPSIS CINEREA; . AUTHOR M.TAMURA,T.MIYAZAKI,Y.TANAKA,M.YOSHIDA,A.NISHIKAWA,T.TONOZUK . 362 1 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14554.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 240 66.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 36 9.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 1.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 25 6.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 51 14.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 103 28.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 2 0 0 1 0 1 0 0 2 1 0 0 0 0 1 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 1 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 74 A V 0 0 170 0, 0.0 170,-0.0 0, 0.0 171,-0.0 0.000 360.0 360.0 360.0 143.6 9.8 30.3 -12.1 2 75 A P - 0 0 64 0, 0.0 2,-0.3 0, 0.0 209,-0.1 -0.264 360.0-144.4 -70.1 155.3 13.0 31.7 -10.6 3 76 A S - 0 0 58 2,-0.1 2,-0.1 207,-0.1 0, 0.0 -0.826 26.4-103.9-111.2 160.8 14.8 34.8 -11.8 4 77 A T S S+ 0 0 147 -2,-0.3 2,-0.1 2,-0.1 -1,-0.0 -0.424 71.9 17.8 -87.5 158.8 18.6 35.2 -11.8 5 78 A G S S- 0 0 45 -2,-0.1 -2,-0.1 3,-0.0 0, 0.0 -0.284 107.8 -11.3 86.6-168.9 20.9 37.1 -9.4 6 79 A N > - 0 0 31 1,-0.1 3,-1.7 -2,-0.1 -2,-0.1 -0.515 58.6-143.7 -66.0 121.0 20.3 38.6 -6.0 7 80 A P T 3 S+ 0 0 1 0, 0.0 -1,-0.1 0, 0.0 168,-0.1 0.713 97.4 56.7 -67.8 -14.1 16.6 38.4 -5.2 8 81 A F T > S+ 0 0 4 2,-0.1 3,-1.8 295,-0.1 2,-0.1 0.661 79.7 115.4 -82.4 -19.2 16.7 41.8 -3.3 9 82 A E T < S+ 0 0 115 -3,-1.7 3,-0.1 1,-0.2 294,-0.0 -0.344 83.7 6.1 -65.9 126.4 18.1 43.7 -6.3 10 83 A G T 3 S+ 0 0 60 1,-0.3 2,-0.4 -2,-0.1 67,-0.3 0.454 101.8 119.3 89.4 3.3 15.8 46.4 -7.7 11 84 A Y < - 0 0 43 -3,-1.8 2,-0.5 65,-0.1 -1,-0.3 -0.807 60.8-134.8-105.4 142.2 13.1 46.1 -5.0 12 85 A D E -a 78 0A 51 65,-3.0 67,-2.3 -2,-0.4 2,-0.6 -0.799 33.3-123.9 -83.4 136.1 11.8 48.5 -2.5 13 86 A I E -a 79 0A 45 -2,-0.5 67,-0.2 65,-0.2 65,-0.1 -0.735 23.5-120.8 -88.6 119.4 11.6 46.7 0.9 14 87 A Y - 0 0 7 65,-2.8 2,-0.6 -2,-0.6 67,-0.3 -0.323 24.6-127.5 -58.9 131.9 8.1 46.9 2.3 15 88 A L - 0 0 75 31,-0.1 -1,-0.1 65,-0.1 33,-0.1 -0.758 24.1-114.5 -90.3 120.9 8.0 48.6 5.7 16 89 A S > - 0 0 8 -2,-0.6 4,-2.1 31,-0.2 5,-0.1 -0.291 20.2-162.9 -53.4 115.3 6.4 46.6 8.4 17 90 A P H > S+ 0 0 42 0, 0.0 4,-2.3 0, 0.0 -1,-0.2 0.818 90.7 60.2 -69.7 -28.2 3.2 48.4 9.6 18 91 A Y H > S+ 0 0 68 2,-0.2 4,-1.7 1,-0.2 5,-0.1 0.936 111.4 38.8 -59.2 -52.6 3.2 46.2 12.8 19 92 A Y H > S+ 0 0 3 2,-0.2 4,-2.8 1,-0.2 5,-0.2 0.867 111.5 57.5 -71.1 -37.9 6.6 47.6 13.7 20 93 A A H X S+ 0 0 26 -4,-2.1 4,-2.8 2,-0.2 -2,-0.2 0.920 106.5 50.3 -58.9 -42.8 5.8 51.1 12.6 21 94 A E H X S+ 0 0 153 -4,-2.3 4,-2.4 1,-0.2 -1,-0.2 0.922 111.8 48.4 -57.6 -47.9 2.8 51.2 15.0 22 95 A E H X S+ 0 0 31 -4,-1.7 4,-2.3 1,-0.2 -2,-0.2 0.913 113.0 46.6 -60.4 -45.1 5.1 50.0 17.8 23 96 A V H X S+ 0 0 0 -4,-2.8 4,-2.7 2,-0.2 5,-0.2 0.908 110.9 51.8 -66.9 -40.2 7.7 52.6 17.0 24 97 A E H X S+ 0 0 90 -4,-2.8 4,-1.8 1,-0.2 -2,-0.2 0.939 112.4 46.1 -61.9 -43.4 5.2 55.4 16.7 25 98 A A H X S+ 0 0 60 -4,-2.4 4,-0.6 1,-0.2 -1,-0.2 0.880 112.8 51.4 -64.7 -40.3 3.7 54.5 20.1 26 99 A A H >< S+ 0 0 1 -4,-2.3 3,-1.2 -5,-0.2 4,-0.4 0.920 108.0 49.8 -63.1 -46.5 7.3 54.2 21.6 27 100 A A H >< S+ 0 0 2 -4,-2.7 3,-1.6 1,-0.3 -1,-0.2 0.868 102.2 63.6 -62.2 -34.8 8.3 57.7 20.3 28 101 A A H 3< S+ 0 0 78 -4,-1.8 -1,-0.3 1,-0.3 -2,-0.2 0.727 102.3 50.5 -61.4 -23.4 5.1 59.1 21.9 29 102 A M T << S+ 0 0 122 -3,-1.2 2,-0.6 -4,-0.6 -1,-0.3 0.506 90.6 94.0 -90.0 -8.2 6.5 58.1 25.3 30 103 A I < - 0 0 10 -3,-1.6 6,-0.1 -4,-0.4 9,-0.0 -0.783 54.4-169.4 -92.6 121.2 9.8 59.7 24.8 31 104 A D + 0 0 148 -2,-0.6 -1,-0.2 4,-0.1 -4,-0.0 0.893 61.4 86.7 -77.9 -42.5 10.0 63.3 26.2 32 105 A D S > S- 0 0 88 1,-0.1 4,-2.7 2,-0.1 5,-0.2 -0.450 71.6-145.0 -64.4 124.6 13.3 64.5 24.7 33 106 A P H > S+ 0 0 95 0, 0.0 4,-2.2 0, 0.0 -1,-0.1 0.882 96.5 48.0 -58.7 -41.6 12.5 66.0 21.3 34 107 A V H > S+ 0 0 83 2,-0.2 4,-2.1 1,-0.2 5,-0.1 0.918 114.5 45.3 -68.8 -43.9 15.8 64.8 19.7 35 108 A L H > S+ 0 0 29 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.890 111.7 53.5 -65.2 -40.8 15.6 61.3 21.0 36 109 A K H X S+ 0 0 76 -4,-2.7 4,-2.1 2,-0.2 -2,-0.2 0.913 109.9 47.7 -56.3 -45.6 11.9 61.1 20.0 37 110 A A H X S+ 0 0 31 -4,-2.2 4,-1.3 2,-0.2 -2,-0.2 0.864 110.8 50.8 -67.9 -37.3 12.9 62.1 16.4 38 111 A K H X S+ 0 0 60 -4,-2.1 4,-0.7 324,-0.3 3,-0.4 0.920 109.0 52.0 -63.0 -43.4 15.7 59.5 16.4 39 112 A A H >< S+ 0 0 0 -4,-2.6 3,-1.4 1,-0.2 4,-0.4 0.913 105.9 54.5 -58.5 -43.9 13.2 56.9 17.5 40 113 A L H >< S+ 0 0 47 -4,-2.1 3,-1.2 1,-0.3 4,-0.3 0.810 95.4 67.3 -62.8 -29.8 10.8 57.8 14.7 41 114 A K H >< S+ 0 0 48 -4,-1.3 3,-1.7 -3,-0.4 -1,-0.3 0.801 88.3 70.8 -55.7 -29.4 13.6 57.3 12.2 42 115 A V G X< S+ 0 0 0 -3,-1.4 3,-1.9 -4,-0.7 -1,-0.2 0.825 83.9 64.4 -64.5 -29.8 13.4 53.6 13.1 43 116 A K G < S+ 0 0 76 -3,-1.2 -1,-0.3 -4,-0.4 -2,-0.2 0.681 96.9 59.5 -70.9 -11.1 10.0 53.0 11.4 44 117 A E G < S+ 0 0 116 -3,-1.7 -1,-0.3 -4,-0.3 -2,-0.2 0.363 87.4 89.1 -89.4 -1.5 11.8 53.8 8.0 45 118 A I S < S- 0 0 14 -3,-1.9 -29,-0.1 -4,-0.1 2,-0.1 -0.891 84.8-119.6-103.8 121.6 14.2 50.9 8.5 46 119 A P + 0 0 24 0, 0.0 261,-0.4 0, 0.0 2,-0.3 -0.349 35.0 178.6 -70.6 141.5 12.9 47.7 7.1 47 120 A T - 0 0 2 -33,-0.3 34,-0.3 -4,-0.1 2,-0.3 -0.834 32.3 -97.3-127.0 165.9 12.4 44.7 9.3 48 121 A F - 0 0 1 259,-1.4 2,-0.5 260,-0.5 34,-0.2 -0.670 31.3-131.8 -83.8 148.1 11.2 41.1 9.0 49 122 A I E -b 82 0A 9 32,-2.6 34,-2.3 -2,-0.3 2,-0.4 -0.881 24.5-138.9-102.5 123.2 7.6 40.3 9.9 50 123 A W E -b 83 0A 32 -2,-0.5 2,-0.7 32,-0.2 3,-0.2 -0.650 18.5-167.2 -95.9 132.7 7.3 37.3 12.1 51 124 A F E +b 84 0A 1 32,-2.7 34,-1.5 -2,-0.4 -1,-0.1 -0.692 33.5 146.6-109.4 76.1 4.7 34.5 11.8 52 125 A D + 0 0 40 -2,-0.7 48,-0.4 32,-0.1 2,-0.3 0.505 64.4 39.1 -93.6 -7.5 5.4 32.9 15.1 53 126 A V S > S- 0 0 30 -3,-0.2 3,-1.7 46,-0.1 4,-0.2 -0.985 79.3-126.3-141.6 146.7 1.7 31.9 15.8 54 127 A V G > S+ 0 0 27 -2,-0.3 3,-1.8 1,-0.3 -1,-0.1 0.757 104.3 73.0 -69.2 -22.8 -0.8 30.5 13.3 55 128 A R G 3 S+ 0 0 154 1,-0.3 -1,-0.3 2,-0.1 4,-0.2 0.745 91.6 60.2 -60.0 -21.7 -3.3 33.3 14.4 56 129 A K G X> S+ 0 0 18 -3,-1.7 3,-1.4 1,-0.2 4,-0.9 0.578 74.3 95.5 -84.1 -8.0 -1.1 35.7 12.5 57 130 A T H X> S+ 0 0 0 -3,-1.8 3,-1.2 1,-0.3 4,-0.9 0.890 80.2 55.0 -56.6 -39.0 -1.4 34.0 9.0 58 131 A P H 3> S+ 0 0 60 0, 0.0 4,-1.7 0, 0.0 -1,-0.3 0.805 97.4 66.5 -65.0 -20.8 -4.3 36.3 7.8 59 132 A D H <> S+ 0 0 31 -3,-1.4 4,-2.5 1,-0.2 5,-0.2 0.854 91.9 61.8 -65.7 -30.6 -2.1 39.3 8.6 60 133 A L H - 0 0 0 -3,-0.1 3,-0.9 1,-0.1 14,-0.3 -0.221 51.4-100.0 -54.7 147.7 7.8 24.2 14.3 88 161 A P T 3 S+ 0 0 0 0, 0.0 14,-0.3 0, 0.0 -1,-0.1 -0.437 111.1 18.4 -67.8 148.3 6.3 21.7 16.8 89 162 A D T 3 S- 0 0 35 12,-2.3 3,-0.3 1,-0.1 13,-0.1 0.905 100.0-164.3 51.7 43.4 8.4 21.2 19.9 90 163 A R < + 0 0 9 -3,-0.9 9,-0.2 11,-0.6 -1,-0.1 -0.113 59.5 17.9 -55.7 148.5 10.0 24.5 18.9 91 164 A D S > S- 0 0 8 46,-0.5 3,-2.1 45,-0.3 -1,-0.2 0.925 75.4-174.9 59.4 53.2 13.2 25.7 20.5 92 165 A a T 3 S+ 0 0 2 45,-0.3 59,-0.2 -3,-0.3 58,-0.2 0.687 75.6 45.9 -62.5 -27.4 14.1 22.2 21.6 93 166 A A T 3 S+ 0 0 40 44,-0.2 -1,-0.3 57,-0.1 2,-0.1 0.444 91.9 107.0 -90.6 -2.9 17.3 23.0 23.6 94 167 A A S < S- 0 0 32 -3,-2.1 3,-0.1 1,-0.1 232,-0.0 -0.408 77.9-124.1 -81.1 154.0 15.7 26.0 25.3 95 168 A A S S+ 0 0 67 1,-0.2 2,-0.3 -2,-0.1 -1,-0.1 0.836 97.6 2.2 -62.4 -33.4 14.8 26.1 29.0 96 169 A A - 0 0 26 228,-0.1 2,-0.4 -5,-0.1 -1,-0.2 -0.968 69.8-149.7-146.5 157.0 11.3 27.1 27.9 97 170 A S - 0 0 26 -2,-0.3 -6,-0.1 2,-0.1 -8,-0.0 -0.997 14.8-158.4-131.7 144.9 9.5 27.6 24.6 98 171 A N + 0 0 63 -2,-0.4 -1,-0.1 226,-0.0 -7,-0.1 0.402 54.0 130.5 -87.9 -2.6 6.6 29.8 23.6 99 172 A G - 0 0 19 -9,-0.2 -10,-0.1 1,-0.1 -2,-0.1 -0.311 51.3-149.8 -64.8 133.2 5.9 27.5 20.6 100 173 A E S S+ 0 0 82 -48,-0.4 2,-0.4 -2,-0.1 -1,-0.1 0.633 70.9 76.9 -77.8 -15.8 2.2 26.6 20.4 101 174 A F - 0 0 18 -14,-0.3 -12,-2.3 -15,-0.1 -11,-0.6 -0.836 56.8-169.8-106.6 134.9 2.5 23.2 18.8 102 175 A S > > - 0 0 58 -2,-0.4 5,-1.8 3,-0.3 3,-1.4 -0.961 26.3-136.7-120.2 137.3 3.6 20.0 20.6 103 176 A L G > 5S+ 0 0 53 -2,-0.4 3,-0.8 1,-0.3 5,-0.3 0.878 107.6 58.7 -58.9 -34.6 4.5 16.8 18.9 104 177 A A G 3 5S+ 0 0 108 1,-0.3 -1,-0.3 2,-0.1 2,-0.1 0.686 106.8 48.4 -67.7 -21.3 2.5 15.0 21.6 105 178 A D G < 5S- 0 0 119 -3,-1.4 -3,-0.3 0, 0.0 -1,-0.3 -0.454 133.8 -77.8-118.7 58.1 -0.6 16.9 20.6 106 179 A G T <>5S+ 0 0 42 -3,-0.8 4,-2.3 -2,-0.1 -3,-0.2 0.750 77.7 154.1 61.5 28.7 -0.7 16.5 16.8 107 180 A G H >< + 0 0 0 -5,-1.8 4,-2.3 1,-0.2 -4,-0.2 0.821 63.9 55.3 -62.0 -36.4 2.0 19.2 16.3 108 181 A M H > S+ 0 0 24 -5,-0.3 4,-2.0 2,-0.2 -1,-0.2 0.951 112.5 42.0 -63.9 -47.3 3.4 17.8 13.0 109 182 A E H > S+ 0 0 117 1,-0.2 4,-2.2 2,-0.2 -2,-0.2 0.905 113.5 53.3 -67.5 -37.3 0.0 18.0 11.3 110 183 A K H X S+ 0 0 91 -4,-2.3 4,-2.0 1,-0.2 -1,-0.2 0.864 107.7 52.5 -62.8 -35.5 -0.8 21.4 12.9 111 184 A Y H X S+ 0 0 0 -4,-2.3 4,-2.5 2,-0.2 -1,-0.2 0.914 107.2 50.2 -66.4 -44.8 2.5 22.7 11.5 112 185 A K H X S+ 0 0 42 -4,-2.0 4,-2.6 1,-0.2 -2,-0.2 0.910 110.2 51.5 -59.3 -39.7 1.7 21.5 8.0 113 186 A D H X S+ 0 0 88 -4,-2.2 4,-2.0 2,-0.2 -2,-0.2 0.880 107.6 52.7 -62.6 -39.3 -1.7 23.3 8.4 114 187 A Y H X S+ 0 0 0 -4,-2.0 4,-2.1 2,-0.2 -2,-0.2 0.931 110.6 46.9 -60.5 -47.2 0.1 26.5 9.5 115 188 A V H X S+ 0 0 1 -4,-2.5 4,-2.9 1,-0.2 -2,-0.2 0.923 110.2 53.7 -61.6 -42.3 2.3 26.4 6.4 116 189 A D H X S+ 0 0 58 -4,-2.6 4,-2.2 1,-0.2 -1,-0.2 0.871 106.7 52.1 -60.2 -37.2 -0.8 25.7 4.3 117 190 A R H X S+ 0 0 91 -4,-2.0 4,-1.5 2,-0.2 -1,-0.2 0.923 110.0 48.1 -66.3 -41.9 -2.4 28.8 5.8 118 191 A L H X S+ 0 0 2 -4,-2.1 4,-2.3 1,-0.2 3,-0.3 0.937 111.4 51.1 -60.0 -46.5 0.6 30.9 4.9 119 192 A A H X S+ 0 0 0 -4,-2.9 4,-2.6 1,-0.2 -2,-0.2 0.875 104.6 56.3 -59.1 -39.4 0.6 29.5 1.4 120 193 A S H X S+ 0 0 42 -4,-2.2 4,-0.6 1,-0.2 -1,-0.2 0.850 109.2 47.4 -64.8 -31.4 -3.1 30.3 0.9 121 194 A E H >< S+ 0 0 19 -4,-1.5 3,-0.9 -3,-0.3 4,-0.5 0.929 111.4 49.7 -71.0 -44.2 -2.3 34.0 1.7 122 195 A I H >< S+ 0 0 7 -4,-2.3 3,-1.7 1,-0.3 -2,-0.2 0.896 102.3 62.3 -63.4 -38.1 0.6 34.1 -0.7 123 196 A R H 3< S+ 0 0 153 -4,-2.6 -1,-0.3 1,-0.3 -2,-0.2 0.762 98.2 58.2 -57.3 -28.8 -1.5 32.5 -3.5 124 197 A K T << S+ 0 0 113 -3,-0.9 -1,-0.3 -4,-0.6 -2,-0.2 0.688 110.1 42.2 -74.6 -19.2 -3.8 35.6 -3.4 125 198 A Y X + 0 0 59 -3,-1.7 3,-1.0 -4,-0.5 -1,-0.2 -0.569 59.6 154.5-133.3 70.3 -0.9 38.1 -4.1 126 199 A P T 3 + 0 0 98 0, 0.0 -1,-0.1 0, 0.0 -3,-0.1 0.543 63.0 72.6 -76.6 -4.9 1.4 36.8 -6.8 127 200 A D T 3 S+ 0 0 110 2,-0.1 2,-0.3 -50,-0.0 -49,-0.2 0.462 86.3 71.6 -96.1 1.3 2.7 40.2 -8.0 128 201 A V S < S- 0 0 15 -3,-1.0 2,-0.3 -51,-0.1 -49,-0.2 -0.841 79.9-122.1-113.9 149.4 4.8 41.0 -5.0 129 202 A R E -c 79 0A 39 -51,-1.9 -49,-2.9 -2,-0.3 2,-0.4 -0.720 23.5-159.7 -91.5 141.1 8.1 39.3 -4.0 130 203 A I E -c 80 0A 5 43,-0.3 45,-2.6 -2,-0.3 2,-0.5 -0.982 10.4-166.5-123.1 132.2 8.6 37.6 -0.7 131 204 A V E -cd 81 175A 0 -51,-2.3 -49,-2.8 -2,-0.4 2,-0.4 -0.990 18.1-167.1-109.4 127.1 11.8 36.7 1.1 132 205 A A E -cd 82 176A 0 43,-2.8 45,-2.7 -2,-0.5 2,-0.5 -0.962 18.6-148.7-119.1 132.9 11.3 34.2 4.0 133 206 A V E -cd 83 177A 0 -51,-2.4 -49,-2.8 -2,-0.4 2,-0.7 -0.888 28.2-138.2 -90.8 127.7 13.6 33.2 6.8 134 207 A I E -cd 84 178A 0 43,-2.5 45,-2.4 -2,-0.5 4,-0.2 -0.814 54.5 -35.9-102.8 108.8 12.8 29.6 7.7 135 208 A E > - 0 0 0 -51,-3.0 3,-0.7 -2,-0.7 4,-0.4 0.922 60.9-144.8 57.8 69.9 12.6 28.5 11.3 136 209 A P T 3 S+ 0 0 7 0, 0.0 -45,-0.3 0, 0.0 -1,-0.1 -0.235 83.1 19.4 -49.6 146.3 15.1 30.2 13.5 137 210 A D T 3 S+ 0 0 43 1,-0.1 -46,-0.5 -47,-0.1 -45,-0.3 0.868 104.3 97.1 60.7 39.2 16.6 28.0 16.3 138 211 A S S X S+ 0 0 2 -3,-0.7 3,-1.8 -4,-0.2 4,-0.4 0.524 82.5 21.6-117.8 -88.0 15.6 24.7 14.6 139 212 A L T >> S+ 0 0 0 -4,-0.4 3,-1.4 1,-0.3 4,-0.7 0.749 111.0 71.5 -62.7 -27.3 18.0 22.7 12.5 140 213 A A H >> S+ 0 0 0 1,-0.3 4,-1.4 2,-0.2 3,-1.0 0.862 91.2 62.4 -56.6 -30.0 21.1 24.3 14.2 141 214 A N H <> S+ 0 0 1 -3,-1.8 4,-2.1 1,-0.2 -1,-0.3 0.781 93.8 61.5 -62.5 -30.2 20.1 22.2 17.3 142 215 A M H <4 S+ 0 0 18 -3,-1.4 -1,-0.2 -4,-0.4 -2,-0.2 0.750 104.3 50.1 -69.8 -22.1 20.7 19.1 15.2 143 216 A V H << S+ 0 0 26 -3,-1.0 -2,-0.2 -4,-0.7 -1,-0.2 0.901 132.3 5.1 -80.4 -43.4 24.3 20.1 14.8 144 217 A T H < S+ 0 0 37 -4,-1.4 3,-0.3 1,-0.1 -2,-0.2 0.593 122.2 57.0-120.5 -16.7 25.2 20.8 18.4 145 218 A N >< + 0 0 36 -4,-2.1 3,-1.9 -5,-0.3 6,-0.3 0.052 57.8 116.5-115.7 28.5 22.4 20.0 20.8 146 219 A M T 3 + 0 0 54 1,-0.3 6,-0.2 -4,-0.2 -1,-0.2 0.633 66.8 75.5 -72.5 -8.7 21.6 16.3 20.2 147 220 A N T 3 S+ 0 0 125 -3,-0.3 2,-0.5 4,-0.1 -1,-0.3 0.725 80.0 86.7 -65.6 -19.9 22.7 15.7 23.8 148 221 A V S X> S- 0 0 41 -3,-1.9 4,-2.0 -7,-0.2 3,-0.6 -0.728 76.4-146.1 -87.3 120.8 19.3 17.2 24.6 149 222 A A H 3> S+ 0 0 64 -2,-0.5 4,-2.4 1,-0.3 5,-0.2 0.877 98.5 55.7 -54.1 -42.3 16.5 14.5 24.6 150 223 A K H 3> S+ 0 0 87 -58,-0.2 4,-1.2 1,-0.2 -1,-0.3 0.860 106.8 51.6 -60.3 -35.7 13.9 17.0 23.3 151 224 A a H <> S+ 0 0 0 -3,-0.6 4,-1.4 -6,-0.3 3,-0.3 0.919 108.6 48.5 -68.7 -42.4 16.1 17.8 20.4 152 225 A R H < S+ 0 0 129 -4,-2.0 4,-0.4 1,-0.2 3,-0.3 0.913 112.8 50.4 -60.4 -36.8 16.6 14.1 19.5 153 226 A G H < S+ 0 0 52 -4,-2.4 4,-0.3 1,-0.2 -1,-0.2 0.744 114.8 43.6 -69.9 -24.0 12.8 13.8 19.8 154 227 A A H X S+ 0 0 0 -4,-1.2 4,-2.7 -3,-0.3 5,-0.2 0.555 85.7 94.0 -98.5 -13.0 12.3 16.8 17.5 155 228 A E H X S+ 0 0 67 -4,-1.4 4,-2.5 -3,-0.3 5,-0.2 0.898 87.2 45.6 -50.7 -51.5 14.9 16.0 14.8 156 229 A A H > S+ 0 0 74 -4,-0.4 4,-2.8 1,-0.2 -1,-0.2 0.907 115.5 47.4 -61.7 -42.7 12.5 14.2 12.4 157 230 A A H > S+ 0 0 7 -4,-0.3 4,-3.0 2,-0.2 5,-0.3 0.862 110.2 51.8 -66.5 -40.1 9.8 16.9 12.8 158 231 A Y H X S+ 0 0 1 -4,-2.7 4,-2.6 2,-0.2 5,-0.3 0.940 114.4 43.2 -61.6 -47.3 12.3 19.8 12.3 159 232 A K H X S+ 0 0 46 -4,-2.5 4,-2.6 -5,-0.2 5,-0.2 0.956 117.2 46.5 -63.6 -48.2 13.6 18.2 9.0 160 233 A E H X S+ 0 0 84 -4,-2.8 4,-2.5 -5,-0.2 -2,-0.2 0.919 115.5 46.2 -59.0 -45.7 10.0 17.3 7.8 161 234 A G H X S+ 0 0 0 -4,-3.0 4,-2.8 2,-0.2 -1,-0.2 0.929 113.4 46.9 -68.0 -45.0 8.7 20.7 8.7 162 235 A V H X S+ 0 0 0 -4,-2.6 4,-2.8 -5,-0.3 -1,-0.2 0.925 114.3 48.1 -63.1 -43.2 11.5 22.7 7.1 163 236 A I H X S+ 0 0 31 -4,-2.6 4,-2.6 -5,-0.3 5,-0.2 0.918 112.4 49.2 -63.9 -41.2 11.4 20.6 4.0 164 237 A Y H X S+ 0 0 57 -4,-2.5 4,-2.6 -5,-0.2 5,-0.2 0.942 112.6 48.0 -63.0 -46.5 7.5 20.9 3.8 165 238 A A H X S+ 0 0 0 -4,-2.8 4,-2.9 1,-0.2 5,-0.3 0.930 112.8 48.1 -59.2 -47.3 7.8 24.7 4.2 166 239 A L H X S+ 0 0 0 -4,-2.8 4,-2.5 2,-0.2 5,-0.2 0.908 113.3 46.9 -61.7 -41.9 10.6 25.0 1.6 167 240 A R H X S+ 0 0 131 -4,-2.6 4,-1.8 -5,-0.2 -2,-0.2 0.930 115.8 45.4 -67.0 -42.9 8.6 22.9 -1.0 168 241 A Q H X S+ 0 0 59 -4,-2.6 4,-0.7 -5,-0.2 -2,-0.2 0.923 117.5 42.7 -65.4 -45.2 5.4 24.8 -0.4 169 242 A L H ><>S+ 0 0 2 -4,-2.9 5,-2.4 -5,-0.2 3,-0.7 0.880 112.3 52.6 -73.9 -35.9 7.1 28.3 -0.5 170 243 A S H ><5S+ 0 0 12 -4,-2.5 3,-1.7 -5,-0.3 -1,-0.2 0.865 102.0 60.6 -66.0 -34.0 9.3 27.4 -3.5 171 244 A A H 3<5S+ 0 0 85 -4,-1.8 -1,-0.2 1,-0.3 -2,-0.2 0.775 108.1 46.0 -60.3 -26.0 6.1 26.3 -5.4 172 245 A L T <<5S- 0 0 59 -3,-0.7 -1,-0.3 -4,-0.7 -2,-0.2 0.270 120.9-107.5-101.6 9.6 4.9 29.9 -4.9 173 246 A G T < 5 + 0 0 24 -3,-1.7 -43,-0.3 1,-0.2 2,-0.3 0.717 64.8 153.4 73.3 22.6 8.1 31.6 -5.9 174 247 A V < - 0 0 2 -5,-2.4 2,-0.6 -6,-0.1 -1,-0.2 -0.659 44.0-129.4 -81.2 138.5 9.1 32.7 -2.4 175 248 A Y E -d 131 0A 7 -45,-2.6 -43,-2.8 -2,-0.3 2,-0.4 -0.828 31.2-161.7 -90.1 118.1 12.9 33.2 -1.9 176 249 A S E -de 132 212A 0 35,-2.7 38,-1.5 -2,-0.6 37,-1.4 -0.833 20.9-169.9-108.6 144.0 13.9 31.3 1.3 177 250 A Y E -de 133 214A 0 -45,-2.7 -43,-2.5 -2,-0.4 38,-0.3 -0.988 23.3-140.2-125.5 120.6 16.8 31.5 3.6 178 251 A V E -de 134 215A 1 36,-2.6 38,-2.3 -2,-0.5 -43,-0.2 -0.581 28.0-104.2 -80.5 135.2 17.0 28.7 6.1 179 252 A D E + e 0 216A 5 -45,-2.4 38,-0.2 -2,-0.3 -40,-0.1 -0.346 38.8 178.0 -59.6 135.5 18.1 29.6 9.6 180 253 A A - 0 0 0 36,-3.0 6,-0.2 1,-0.4 -1,-0.1 -0.161 35.2-120.0-133.7 43.4 21.7 28.6 10.3 181 254 A G - 0 0 3 36,-0.1 37,-2.1 4,-0.1 38,-0.5 -0.253 39.1 -87.4 62.2-141.6 22.6 29.8 13.7 182 255 A H >>> - 0 0 21 35,-0.2 3,-2.0 36,-0.2 4,-1.8 -0.918 43.4 -76.4-161.3 176.1 25.4 32.2 14.2 183 256 A A T 345S+ 0 0 0 1,-0.3 4,-0.5 -2,-0.3 5,-0.2 0.807 126.8 51.2 -57.5 -35.3 29.2 32.3 14.7 184 257 A G T 345S+ 0 0 14 3,-0.2 -1,-0.3 2,-0.1 -3,-0.1 0.486 119.7 35.3 -81.8 -6.6 29.0 31.3 18.4 185 258 A W T <45S+ 0 0 47 -3,-2.0 3,-0.3 -5,-0.1 -2,-0.2 0.758 137.2 8.8-108.0 -68.3 26.7 28.4 17.6 186 259 A L T <5S+ 0 0 0 -4,-1.8 -3,-0.2 -6,-0.2 9,-0.2 0.482 112.0 79.2 -97.4 -5.5 27.7 26.7 14.3 187 260 A G < + 0 0 0 -5,-0.9 52,-0.2 -4,-0.5 -1,-0.2 0.685 61.7 110.3 -81.1 -18.6 31.0 28.7 13.7 188 261 A W S >> S- 0 0 87 -3,-0.3 3,-2.2 -5,-0.2 4,-0.8 -0.330 83.1-116.9 -54.9 137.0 33.1 26.6 16.1 189 262 A N H >> S+ 0 0 122 1,-0.3 3,-1.2 2,-0.2 4,-0.6 0.855 112.5 55.7 -52.3 -43.6 35.4 24.6 13.9 190 263 A A H 34 S+ 0 0 82 1,-0.2 -1,-0.3 2,-0.1 -2,-0.1 0.685 108.3 50.3 -60.9 -22.0 34.0 21.2 15.0 191 264 A N H <> S+ 0 0 30 -3,-2.2 4,-1.9 2,-0.1 -1,-0.2 0.583 88.9 81.1 -95.1 -11.9 30.5 22.3 13.9 192 265 A L H S+ 0 0 42 0, 0.0 4,-2.4 0, 0.0 -1,-0.2 0.881 112.9 52.5 -65.3 -30.7 28.2 18.7 10.2 195 268 A S H X S+ 0 0 0 -4,-1.9 4,-2.8 2,-0.2 5,-0.3 0.942 109.2 47.9 -63.6 -47.2 26.5 22.0 9.5 196 269 A A H X S+ 0 0 0 -4,-2.5 4,-2.1 1,-0.2 5,-0.2 0.924 113.2 48.7 -61.6 -42.3 27.5 21.9 5.8 197 270 A R H X S+ 0 0 129 -4,-2.5 4,-1.9 -5,-0.2 -1,-0.2 0.937 113.6 46.3 -61.7 -47.8 26.3 18.3 5.5 198 271 A L H X S+ 0 0 17 -4,-2.4 4,-2.1 2,-0.2 -2,-0.2 0.947 114.4 44.3 -63.5 -49.5 23.0 19.0 7.2 199 272 A F H X S+ 0 0 1 -4,-2.8 4,-2.3 1,-0.2 -1,-0.2 0.895 112.7 52.2 -68.6 -34.7 22.0 22.1 5.3 200 273 A A H X S+ 0 0 9 -4,-2.1 4,-2.3 -5,-0.3 -1,-0.2 0.884 109.0 52.0 -64.7 -34.8 23.1 20.6 2.0 201 274 A Q H X S+ 0 0 69 -4,-1.9 4,-2.8 2,-0.2 -2,-0.2 0.887 108.2 50.1 -66.4 -40.9 20.9 17.6 2.8 202 275 A I H X S+ 0 0 2 -4,-2.1 4,-2.0 2,-0.2 -2,-0.2 0.924 109.5 51.2 -62.4 -44.6 17.9 19.9 3.5 203 276 A Y H <>S+ 0 0 39 -4,-2.3 5,-2.5 1,-0.2 6,-0.3 0.932 112.8 47.1 -56.5 -47.5 18.5 21.7 0.2 204 277 A K H ><5S+ 0 0 92 -4,-2.3 3,-1.8 1,-0.2 -2,-0.2 0.944 113.7 45.4 -59.1 -53.6 18.5 18.3 -1.6 205 278 A D H 3<5S+ 0 0 55 -4,-2.8 -1,-0.2 1,-0.3 -2,-0.2 0.747 107.4 59.0 -67.3 -23.8 15.4 16.9 0.1 206 279 A A T 3<5S- 0 0 5 -4,-2.0 3,-0.4 -5,-0.2 -1,-0.3 0.388 125.8-102.0 -81.5 -0.4 13.6 20.2 -0.5 207 280 A G T < 5 - 0 0 42 -3,-1.8 -3,-0.2 1,-0.2 -2,-0.1 0.514 43.3 -93.8 98.3 7.3 14.2 19.6 -4.2 208 281 A R < + 0 0 142 -5,-2.5 -1,-0.2 -6,-0.2 -4,-0.1 0.750 61.2 175.5 58.9 29.8 17.1 22.0 -5.0 209 282 A S > - 0 0 32 -3,-0.4 3,-2.0 -6,-0.3 -1,-0.2 -0.416 37.9-132.3 -64.0 139.0 14.8 24.8 -6.1 210 283 A A T 3 S+ 0 0 63 1,-0.3 -1,-0.2 -2,-0.1 -207,-0.1 0.677 106.0 72.8 -66.5 -14.4 16.8 28.0 -6.9 211 284 A F T 3 S+ 0 0 13 1,-0.1 -35,-2.7 -36,-0.1 2,-1.6 0.720 76.6 80.8 -69.6 -20.9 14.1 29.7 -4.8 212 285 A I E < +e 176 0A 3 -3,-2.0 -1,-0.1 -37,-0.2 -35,-0.1 -0.713 69.2 175.1 -82.1 89.7 15.9 28.1 -1.8 213 286 A R E - 0 0 49 -2,-1.6 48,-2.0 -37,-1.4 2,-0.3 0.822 38.9 -84.4 -79.2 -32.4 18.4 30.8 -1.9 214 287 A G E -ef 177 261A 0 -38,-1.5 -36,-2.6 46,-0.3 2,-0.3 -0.908 56.9 -36.3 166.3-141.0 20.6 30.1 1.1 215 288 A L E -ef 178 262A 0 46,-2.7 48,-1.9 -38,-0.3 2,-0.4 -0.862 33.0-140.5-126.1 153.2 20.9 30.6 4.8 216 289 A A E -ef 179 263A 0 -38,-2.3 -36,-3.0 -2,-0.3 2,-0.3 -0.943 24.3-167.8-113.5 137.2 20.2 33.3 7.4 217 290 A T E + f 0 264A 0 46,-2.4 48,-2.5 -2,-0.4 -35,-0.2 -0.845 57.8 22.0-126.3 159.6 22.6 34.0 10.3 218 291 A N S > S+ 0 0 0 -37,-2.1 3,-2.5 -2,-0.3 -36,-0.2 0.676 72.7 179.9 67.5 19.5 22.7 35.9 13.5 219 292 A V T 3 S- 0 0 18 -38,-0.5 -1,-0.2 1,-0.3 3,-0.1 -0.337 72.4 -9.0 -60.9 124.9 18.9 35.9 13.7 220 293 A S T 3 S+ 0 0 29 1,-0.2 -1,-0.3 -2,-0.1 2,-0.1 0.646 117.3 115.5 63.0 16.4 17.8 37.7 16.9 221 294 A N < - 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