==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=7-AUG-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE 08-MAY-09 2WI4 . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN, HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR P.A.BROUGH,X.BARRIL,J.BORGOGNONI,P.CHENE,N.G.M.DAVIES,B.DAVI . 208 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10723.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 158 76.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 41 19.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 16 7.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 34 16.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 56 26.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 0 0 1 1 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 2 0 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A E 0 0 199 0, 0.0 2,-0.5 0, 0.0 158,-0.4 0.000 360.0 360.0 360.0 128.9 7.5 28.9 38.3 2 17 A V - 0 0 68 156,-0.1 2,-0.4 154,-0.0 156,-0.2 -0.790 360.0-152.6-103.8 119.7 8.7 27.3 35.1 3 18 A E E -A 157 0A 76 154,-2.3 154,-2.2 -2,-0.5 2,-0.4 -0.766 12.4-148.2 -87.0 136.7 11.4 24.6 35.0 4 19 A T E -A 156 0A 92 -2,-0.4 2,-0.3 152,-0.2 152,-0.2 -0.903 15.0-171.7-109.6 135.8 13.4 24.3 31.7 5 20 A F E -A 155 0A 48 150,-4.2 150,-2.7 -2,-0.4 2,-0.4 -0.869 21.8-126.5-123.9 156.5 14.8 21.0 30.5 6 21 A A E -A 154 0A 81 -2,-0.3 148,-0.3 148,-0.2 3,-0.1 -0.850 31.9-118.9-101.0 135.3 17.2 19.9 27.7 7 22 A F - 0 0 17 146,-1.9 86,-0.0 -2,-0.4 -1,-0.0 -0.374 41.8 -92.4 -66.3 154.4 15.9 17.3 25.3 8 23 A Q >> - 0 0 60 1,-0.1 4,-2.1 4,-0.0 3,-0.7 -0.347 45.3-104.3 -52.0 150.0 18.0 14.1 25.3 9 24 A A H 3> S+ 0 0 67 1,-0.2 4,-1.8 2,-0.2 5,-0.1 0.876 119.6 48.5 -48.3 -44.3 20.7 14.4 22.5 10 25 A E H 3> S+ 0 0 58 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.805 109.7 51.4 -68.9 -35.7 18.9 12.0 20.2 11 26 A I H <> S+ 0 0 1 -3,-0.7 4,-2.9 2,-0.2 -1,-0.2 0.906 107.5 52.2 -70.5 -45.4 15.5 13.7 20.5 12 27 A A H X S+ 0 0 30 -4,-2.1 4,-1.3 2,-0.2 -2,-0.2 0.906 112.5 47.1 -51.2 -49.8 16.9 17.1 19.8 13 28 A Q H X S+ 0 0 119 -4,-1.8 4,-2.0 -5,-0.2 3,-0.3 0.905 110.6 51.6 -60.8 -45.6 18.4 15.6 16.6 14 29 A L H X S+ 0 0 0 -4,-2.2 4,-1.9 1,-0.2 -2,-0.2 0.915 107.7 53.3 -57.7 -43.4 15.1 13.9 15.8 15 30 A M H X S+ 0 0 3 -4,-2.9 4,-1.3 1,-0.2 -1,-0.2 0.790 109.5 46.5 -72.7 -24.7 13.4 17.2 16.1 16 31 A S H X S+ 0 0 57 -4,-1.3 4,-2.6 -3,-0.3 5,-0.3 0.741 107.6 57.3 -79.7 -31.7 15.7 19.1 13.6 17 32 A L H X S+ 0 0 48 -4,-2.0 4,-2.7 2,-0.2 -2,-0.2 0.968 111.2 42.8 -58.4 -48.6 15.5 16.3 11.2 18 33 A I H < S+ 0 0 3 -4,-1.9 -2,-0.2 1,-0.2 -1,-0.2 0.859 118.5 44.7 -67.4 -38.2 11.7 16.7 11.1 19 34 A I H < S+ 0 0 70 -4,-1.3 -1,-0.2 -5,-0.2 -2,-0.2 0.836 122.4 36.4 -74.9 -33.8 11.9 20.5 11.0 20 35 A N H < S+ 0 0 120 -4,-2.6 2,-0.2 2,-0.1 -2,-0.2 0.766 89.8 96.2 -92.9 -29.3 14.7 20.6 8.4 21 36 A T S < S- 0 0 64 -4,-2.7 2,-0.5 -5,-0.3 -4,-0.0 -0.455 76.5-120.5 -75.0 129.1 14.0 17.8 5.9 22 37 A F + 0 0 182 -2,-0.2 2,-0.3 2,-0.0 -1,-0.1 -0.534 53.2 149.4 -64.3 119.0 12.1 18.7 2.7 23 38 A Y - 0 0 33 -2,-0.5 3,-0.1 -5,-0.1 -2,-0.0 -0.805 30.7-168.5-160.3 106.0 9.1 16.5 3.0 24 39 A S S S+ 0 0 90 -2,-0.3 2,-1.7 1,-0.2 3,-0.2 0.691 70.6 83.0 -80.5 -21.4 5.7 17.5 1.5 25 40 A N > + 0 0 71 1,-0.2 3,-0.8 2,-0.1 -1,-0.2 -0.437 47.4 145.6 -85.2 63.3 3.5 14.9 3.1 26 41 A K T > + 0 0 40 -2,-1.7 3,-2.0 1,-0.2 4,-0.2 0.627 46.5 87.9 -73.2 -19.8 2.9 16.6 6.5 27 42 A E T >> + 0 0 12 1,-0.3 3,-1.3 -3,-0.2 4,-0.6 0.653 68.8 79.9 -58.3 -13.6 -0.6 15.4 7.0 28 43 A I H <> S+ 0 0 2 -3,-0.8 4,-1.3 1,-0.3 -1,-0.3 0.736 72.4 79.5 -71.2 -14.6 0.7 12.3 8.7 29 44 A F H <> S+ 0 0 1 -3,-2.0 4,-1.5 1,-0.2 -1,-0.3 0.825 88.2 58.0 -56.3 -35.0 1.2 14.3 11.9 30 45 A L H <> S+ 0 0 2 -3,-1.3 4,-2.6 1,-0.2 -1,-0.2 0.900 103.4 46.0 -74.2 -39.7 -2.5 14.0 12.7 31 46 A R H X S+ 0 0 57 -4,-0.6 4,-1.3 -3,-0.3 -1,-0.2 0.840 109.1 58.6 -72.4 -21.6 -3.0 10.2 12.8 32 47 A E H X S+ 0 0 14 -4,-1.3 4,-1.7 2,-0.2 91,-0.2 0.921 111.7 40.5 -69.4 -40.0 0.2 10.0 14.9 33 48 A L H X S+ 0 0 2 -4,-1.5 4,-1.4 2,-0.2 -2,-0.2 0.926 115.0 50.4 -71.0 -49.9 -1.4 12.2 17.6 34 49 A I H X S+ 0 0 0 -4,-2.6 4,-1.5 2,-0.2 -1,-0.2 0.748 111.4 49.5 -57.6 -26.1 -4.9 10.6 17.3 35 50 A S H X S+ 0 0 45 -4,-1.3 4,-2.3 2,-0.2 -1,-0.2 0.875 105.1 56.7 -90.8 -36.0 -3.3 7.1 17.7 36 51 A N H X S+ 0 0 65 -4,-1.7 4,-1.7 1,-0.2 -2,-0.2 0.843 109.4 48.1 -51.4 -38.8 -1.3 8.3 20.7 37 52 A S H X S+ 0 0 5 -4,-1.4 4,-2.2 2,-0.2 5,-0.2 0.856 106.1 55.9 -73.6 -37.7 -4.8 9.2 22.1 38 53 A S H X S+ 0 0 17 -4,-1.5 4,-2.5 1,-0.2 -2,-0.2 0.939 108.9 47.7 -60.7 -44.9 -6.2 5.9 21.2 39 54 A D H X S+ 0 0 92 -4,-2.3 4,-2.4 1,-0.2 -1,-0.2 0.880 111.3 49.9 -60.1 -46.7 -3.4 4.2 23.2 40 55 A A H X S+ 0 0 19 -4,-1.7 41,-1.3 2,-0.2 4,-1.1 0.804 112.5 47.4 -63.1 -32.9 -3.9 6.5 26.3 41 56 A L H X S+ 0 0 0 -4,-2.2 4,-2.0 39,-0.3 3,-0.4 0.916 109.9 53.5 -74.4 -42.1 -7.7 5.8 26.2 42 57 A D H X S+ 0 0 67 -4,-2.5 4,-2.3 -5,-0.2 3,-0.4 0.960 107.4 53.6 -49.0 -52.3 -7.0 2.0 25.9 43 58 A K H X S+ 0 0 120 -4,-2.4 4,-1.7 1,-0.3 -1,-0.2 0.813 109.4 44.0 -63.5 -31.0 -4.8 2.2 28.9 44 59 A I H X S+ 0 0 1 -4,-1.1 4,-2.0 -3,-0.4 -1,-0.3 0.792 111.7 54.2 -84.0 -26.7 -7.4 3.9 31.3 45 60 A R H X S+ 0 0 123 -4,-2.0 4,-0.9 -3,-0.4 -2,-0.2 0.908 110.1 46.4 -70.6 -40.9 -10.2 1.5 30.1 46 61 A Y H >X S+ 0 0 151 -4,-2.3 3,-1.2 -5,-0.2 4,-0.8 0.969 114.4 47.6 -63.3 -48.4 -8.1 -1.5 30.9 47 62 A E H 3< S+ 0 0 39 -4,-1.7 3,-0.3 1,-0.3 -1,-0.2 0.807 107.1 55.7 -64.9 -34.1 -7.1 -0.1 34.3 48 63 A S H >< S+ 0 0 15 -4,-2.0 3,-0.9 1,-0.2 -1,-0.3 0.678 93.7 72.7 -71.5 -18.3 -10.6 0.9 35.3 49 64 A L H << S+ 0 0 122 -3,-1.2 -1,-0.2 -4,-0.9 -2,-0.2 0.953 108.4 31.3 -58.0 -50.5 -11.6 -2.8 34.7 50 65 A T T 3< S+ 0 0 109 -4,-0.8 -1,-0.2 -3,-0.3 -2,-0.2 0.093 136.1 27.0 -97.6 20.8 -9.9 -3.8 37.9 51 66 A D X - 0 0 56 -3,-0.9 3,-1.8 1,-0.0 -1,-0.3 -0.333 63.5-172.8-176.4 86.8 -10.5 -0.6 39.7 52 67 A P G > S+ 0 0 98 0, 0.0 3,-1.3 0, 0.0 -4,-0.1 0.613 76.0 76.9 -73.7 -8.2 -13.5 1.4 38.7 53 68 A S G > S+ 0 0 64 1,-0.2 3,-2.1 2,-0.1 4,-0.1 0.679 77.2 81.2 -69.2 -12.5 -12.8 4.5 40.9 54 69 A K G < S+ 0 0 54 -3,-1.8 3,-0.4 1,-0.3 -1,-0.2 0.729 86.8 54.9 -67.1 -18.3 -10.2 5.3 38.2 55 70 A L G X S+ 0 0 34 -3,-1.3 3,-1.4 1,-0.2 -1,-0.3 0.193 74.8 102.8 -95.4 14.9 -13.0 6.8 36.1 56 71 A D T < S+ 0 0 131 -3,-2.1 -1,-0.2 1,-0.2 3,-0.1 0.608 79.0 56.6 -67.3 -12.8 -14.1 9.1 38.9 57 72 A S T 3 S- 0 0 37 -3,-0.4 -1,-0.2 1,-0.4 2,-0.1 0.269 132.7 -28.5-103.9 4.8 -12.3 11.9 36.9 58 73 A G < - 0 0 24 -3,-1.4 -1,-0.4 108,-0.1 -2,-0.0 -0.258 44.0-154.0 151.6 134.7 -14.5 11.3 33.9 59 74 A K + 0 0 147 -3,-0.1 2,-0.1 -2,-0.1 -3,-0.1 0.847 68.1 94.7 -86.0 -39.3 -16.3 8.3 32.3 60 75 A E - 0 0 123 -5,-0.1 2,-0.7 1,-0.1 19,-0.0 -0.310 55.9-160.6 -66.6 129.8 -16.4 9.4 28.7 61 76 A L + 0 0 29 -2,-0.1 2,-0.3 17,-0.1 -1,-0.1 -0.941 38.4 129.6-112.1 110.9 -13.6 8.0 26.5 62 77 A H - 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0 0 18 -41,-1.3 59,-0.5 -44,-0.1 87,-0.2 0.742 67.4-147.1 -76.4 -22.8 -4.9 8.1 31.0 82 97 A G - 0 0 4 85,-0.2 2,-0.4 57,-0.2 57,-0.2 -0.163 19.8 -94.8 80.0 173.4 -3.0 11.5 31.1 83 98 A M - 0 0 33 85,-0.4 56,-0.4 62,-0.1 62,-0.2 -0.995 24.8-130.7-134.7 143.7 0.7 11.7 32.1 84 99 A T >> - 0 0 25 -2,-0.4 4,-2.5 54,-0.1 3,-0.5 -0.328 36.2-100.0 -83.4 167.6 2.5 12.3 35.3 85 100 A K H 3> S+ 0 0 60 1,-0.3 4,-2.8 2,-0.2 5,-0.2 0.910 123.8 52.5 -55.0 -42.9 5.3 14.8 35.8 86 101 A A H 3>>S+ 0 0 51 2,-0.2 5,-3.4 1,-0.2 4,-0.9 0.813 108.3 50.4 -68.1 -29.0 7.9 12.1 35.5 87 102 A D H <4>S+ 0 0 40 -3,-0.5 5,-2.8 3,-0.2 6,-0.4 0.983 111.7 47.5 -65.1 -59.4 6.5 10.8 32.2 88 103 A L H <5S+ 0 0 11 -4,-2.5 -2,-0.2 3,-0.2 -3,-0.2 0.907 127.3 26.9 -41.4 -54.1 6.5 14.3 30.8 89 104 A I H <5S+ 0 0 33 -4,-2.8 -3,-0.2 -5,-0.2 4,-0.2 0.983 139.3 1.6 -79.6 -71.2 10.1 14.9 31.9 90 105 A N T >X5S+ 0 0 98 -4,-0.9 4,-2.9 -5,-0.2 3,-0.9 0.942 120.7 54.8 -92.5 -51.7 11.9 11.7 32.2 91 106 A N H 3>X S+ 0 0 122 -4,-1.5 4,-1.2 -5,-0.2 3,-1.1 0.873 106.7 56.0 -85.7 -46.4 11.8 5.5 25.8 96 111 A A H 3X S+ 0 0 8 -4,-1.0 4,-1.1 1,-0.2 -1,-0.2 0.426 91.5 84.6 -68.9 7.6 11.7 7.5 22.6 97 112 A K H 3> S+ 0 0 90 -4,-0.3 4,-0.6 -3,-0.2 -1,-0.2 0.878 96.5 33.1 -76.4 -40.2 15.5 7.2 22.9 98 113 A S H X> S+ 0 0 87 -3,-1.1 4,-2.5 -4,-0.3 3,-0.8 0.895 115.3 57.9 -76.4 -45.9 15.7 3.7 21.2 99 114 A G H 3X S+ 0 0 13 -4,-1.2 4,-2.7 1,-0.3 5,-0.2 0.896 105.3 52.5 -48.3 -43.4 12.8 4.5 18.8 100 115 A T H 3X S+ 0 0 2 -4,-1.1 4,-1.1 2,-0.2 -1,-0.3 0.759 109.7 47.8 -68.3 -29.2 14.8 7.5 17.6 101 116 A K H < S+ 0 0 112 -4,-2.9 3,-2.1 1,-0.2 -2,-0.2 0.970 111.0 50.5 -57.4 -54.1 18.9 4.1 10.9 106 121 A A H 3<>S+ 0 0 24 -4,-2.8 5,-1.6 1,-0.3 4,-0.2 0.921 93.7 76.9 -42.5 -50.1 15.8 3.2 8.9 107 122 A L T 3<5S+ 0 0 37 -4,-2.7 2,-0.3 -5,-0.3 -1,-0.3 0.523 96.5 47.4 -53.5 -4.7 15.8 6.7 7.4 108 123 A Q T < 5S+ 0 0 150 -3,-2.1 -1,-0.2 -4,-0.2 4,-0.1 -0.720 97.9 60.8-132.4 93.5 18.7 5.7 5.2 109 124 A A T 5S- 0 0 97 -2,-0.3 -2,-0.2 2,-0.2 -3,-0.1 -0.117 132.9 -88.2 162.1 -3.2 17.6 2.4 3.7 110 125 A G T 5S+ 0 0 63 1,-0.3 -3,-0.2 -4,-0.2 -4,-0.1 0.651 79.4 147.2 80.3 21.3 14.9 4.7 2.4 111 126 A A < - 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