==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=22-APR-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 17-JAN-11 2Y5S . COMPND 2 MOLECULE: DIHYDROPTEROATE SYNTHASE; . SOURCE 2 ORGANISM_SCIENTIFIC: BURKHOLDERIA CENOCEPACIA; . AUTHOR R.E.MORGAN,G.O.BATOT,J.M.DEMENT,V.A.RAO,T.C.EADSFORTH,W.N.HU . 561 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 22265.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 400 71.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 69 12.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 18 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 51 9.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 60 10.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 174 31.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 13 2.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 2 0 0 2 1 1 1 0 2 1 2 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 1 5 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 4 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A T 0 0 120 0, 0.0 2,-0.1 0, 0.0 274,-0.0 0.000 360.0 360.0 360.0 131.0 45.1 4.8 15.4 2 4 A F - 0 0 115 1,-0.0 250,-0.1 0, 0.0 249,-0.0 -0.365 360.0-167.9 -68.5 138.8 47.3 1.8 14.5 3 5 A L - 0 0 81 -2,-0.1 14,-0.1 15,-0.0 251,-0.1 -0.917 20.0-134.7-127.8 104.3 50.9 2.6 13.4 4 6 A P - 0 0 11 0, 0.0 12,-0.6 0, 0.0 3,-0.1 -0.251 32.9 -96.7 -56.1 143.3 52.7 -0.5 11.9 5 7 A A - 0 0 3 207,-0.6 249,-0.0 1,-0.1 0, 0.0 -0.310 50.3 -93.9 -60.5 145.3 56.3 -1.0 13.1 6 8 A P - 0 0 37 0, 0.0 2,-0.5 0, 0.0 9,-0.2 -0.157 32.7-138.9 -65.5 154.0 59.0 0.4 10.8 7 9 A L E -A 14 0A 0 7,-2.5 7,-3.0 -3,-0.1 2,-0.5 -0.957 3.7-144.2-120.1 116.8 60.7 -1.7 8.1 8 10 A Q E +A 13 0A 46 167,-2.9 2,-0.2 -2,-0.5 5,-0.2 -0.677 28.8 179.4 -72.4 120.5 64.4 -1.5 7.4 9 11 A C E > -A 12 0A 0 3,-3.1 3,-2.0 -2,-0.5 2,-0.5 -0.562 43.5 -90.1-137.6 67.1 64.3 -2.0 3.6 10 12 A G T 3 S+ 0 0 18 117,-2.9 -1,-0.2 1,-0.3 96,-0.1 -0.503 113.7 3.0 68.5-115.9 67.7 -1.9 1.9 11 13 A R T 3 S+ 0 0 88 -2,-0.5 2,-0.3 93,-0.2 -1,-0.3 0.619 129.6 69.7 -71.1 -15.7 68.4 1.7 0.9 12 14 A F E < -A 9 0A 34 -3,-2.0 -3,-3.1 94,-0.1 2,-0.7 -0.824 64.6-151.2-115.8 143.8 65.2 2.8 2.5 13 15 A E E -A 8 0A 109 -2,-0.3 2,-0.5 -5,-0.2 -5,-0.2 -0.965 29.0-154.8-103.9 109.1 63.8 3.1 6.1 14 16 A L E -A 7 0A 18 -7,-3.0 -7,-2.5 -2,-0.7 2,-0.3 -0.752 14.5-177.5 -91.7 130.6 60.1 2.6 5.6 15 17 A T - 0 0 58 -2,-0.5 3,-0.3 -9,-0.2 -10,-0.1 -0.911 21.6-138.3-122.8 155.4 57.8 4.0 8.1 16 18 A F + 0 0 3 -12,-0.6 -2,-0.0 -2,-0.3 4,-0.0 -0.257 52.2 134.9-120.7 47.5 54.0 3.6 8.0 17 19 A E S S+ 0 0 116 1,-0.2 -1,-0.2 -14,-0.1 0, 0.0 0.854 95.2 16.7 -53.4 -38.2 52.3 6.9 8.8 18 20 A R S S- 0 0 118 -3,-0.3 -1,-0.2 236,-0.1 -3,-0.1 -0.972 101.6 -97.9-127.9 152.0 50.3 5.8 5.8 19 21 A P - 0 0 12 0, 0.0 2,-0.3 0, 0.0 236,-0.2 -0.332 40.5-129.9 -61.9 149.3 50.1 2.3 4.3 20 22 A L E -b 255 0B 16 234,-2.8 236,-2.1 28,-0.0 2,-0.6 -0.753 7.8-133.4-105.1 151.6 52.3 1.8 1.2 21 23 A V E -b 256 0B 3 25,-0.3 27,-2.7 -2,-0.3 28,-1.7 -0.918 12.2-159.8-108.3 119.0 51.3 0.4 -2.1 22 24 A M E -bc 257 49B 0 234,-3.1 236,-2.6 -2,-0.6 2,-0.3 -0.898 14.4-145.8 -97.1 115.0 53.5 -2.3 -3.7 23 25 A G E -bc 258 50B 0 26,-2.9 28,-2.7 -2,-0.6 2,-0.6 -0.667 15.0-124.3 -84.7 134.2 52.9 -2.5 -7.5 24 26 A I E - c 0 51B 20 234,-2.2 2,-0.8 -2,-0.3 28,-0.1 -0.686 22.8-169.3 -82.6 118.4 53.2 -5.9 -9.0 25 27 A L E - c 0 52B 0 26,-2.8 28,-2.1 -2,-0.6 2,-0.7 -0.811 4.7-164.3-111.8 86.7 55.7 -6.0 -11.9 26 28 A N E - c 0 53B 74 -2,-0.8 28,-0.2 26,-0.2 26,-0.1 -0.655 5.0-173.1 -69.1 108.9 55.2 -9.4 -13.6 27 29 A A + 0 0 14 26,-3.1 -1,-0.1 -2,-0.7 27,-0.1 0.020 41.5 122.1 -96.4 26.1 58.4 -9.7 -15.7 28 30 A T 0 0 42 1,-0.2 27,-0.1 25,-0.2 -2,-0.1 -0.760 360.0 360.0 -89.3 129.2 57.2 -12.9 -17.5 29 31 A P 0 0 134 0, 0.0 -1,-0.2 0, 0.0 -3,-0.0 0.970 360.0 360.0 -66.2 360.0 57.1 -12.8 -21.3 30 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 31 42 A A > 0 0 71 0, 0.0 4,-1.6 0, 0.0 2,-1.2 0.000 360.0 360.0 360.0-110.2 59.8 -7.8 -22.7 32 43 A R T 4 + 0 0 160 1,-0.2 -5,-0.0 2,-0.2 -4,-0.0 -0.274 360.0 37.4 -83.7 48.8 62.7 -6.5 -20.6 33 44 A D T > S+ 0 0 95 -2,-1.2 4,-1.5 3,-0.0 -1,-0.2 0.219 105.1 62.2-172.5 -42.2 61.6 -3.0 -21.6 34 45 A D H > S+ 0 0 64 2,-0.2 4,-1.9 1,-0.2 -2,-0.2 0.818 104.8 55.4 -55.0 -40.3 57.8 -3.3 -21.6 35 46 A A H X S+ 0 0 0 -4,-1.6 4,-2.2 1,-0.2 -1,-0.2 0.901 104.2 52.9 -61.9 -41.9 58.5 -4.1 -17.9 36 47 A L H > S+ 0 0 39 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.876 108.9 46.6 -64.8 -42.4 60.4 -0.7 -17.5 37 48 A R H X S+ 0 0 154 -4,-1.5 4,-2.3 2,-0.2 -1,-0.2 0.887 111.3 53.4 -69.0 -37.5 57.5 1.4 -18.9 38 49 A R H X S+ 0 0 84 -4,-1.9 4,-2.5 2,-0.2 -2,-0.2 0.908 108.7 49.9 -55.9 -46.7 55.1 -0.5 -16.7 39 50 A A H X S+ 0 0 0 -4,-2.2 4,-2.3 2,-0.2 -2,-0.2 0.927 110.3 49.3 -60.0 -48.1 57.3 0.4 -13.7 40 51 A E H X S+ 0 0 117 -4,-2.2 4,-2.3 1,-0.2 -1,-0.2 0.895 111.8 49.5 -57.8 -42.6 57.4 4.1 -14.6 41 52 A R H X S+ 0 0 161 -4,-2.3 4,-1.9 2,-0.2 -2,-0.2 0.930 110.1 49.4 -64.1 -46.6 53.6 4.1 -15.0 42 53 A M H <>S+ 0 0 14 -4,-2.5 5,-3.1 2,-0.2 4,-0.3 0.883 111.2 49.7 -62.9 -38.6 53.0 2.4 -11.6 43 54 A I H ><5S+ 0 0 51 -4,-2.3 3,-1.5 3,-0.2 -1,-0.2 0.940 111.1 49.7 -60.8 -45.8 55.4 5.0 -10.0 44 55 A A H 3<5S+ 0 0 83 -4,-2.3 -2,-0.2 1,-0.3 -1,-0.2 0.807 107.8 54.7 -61.8 -30.9 53.4 7.8 -11.7 45 56 A E T 3<5S- 0 0 67 -4,-1.9 -1,-0.3 -5,-0.1 -2,-0.2 0.509 132.6 -91.6 -82.1 -7.1 50.2 6.2 -10.4 46 57 A G T < 5 + 0 0 27 -3,-1.5 -25,-0.3 -4,-0.3 -3,-0.2 0.541 64.1 164.3 110.8 10.6 51.6 6.4 -6.9 47 58 A A < - 0 0 8 -5,-3.1 -1,-0.2 1,-0.1 -25,-0.2 -0.373 20.0-167.7 -60.0 133.7 53.4 3.0 -6.2 48 59 A D S S+ 0 0 30 -27,-2.7 2,-0.3 1,-0.2 -26,-0.2 0.674 74.2 16.6 -94.8 -26.7 55.7 3.1 -3.2 49 60 A L E -c 22 0B 1 -28,-1.7 -26,-2.9 36,-0.1 2,-0.4 -0.953 68.0-142.7-138.8 159.2 57.4 -0.2 -4.0 50 61 A L E -cd 23 87B 0 36,-2.1 38,-3.1 -2,-0.3 2,-0.7 -0.997 9.2-150.5-124.5 131.8 57.7 -2.4 -7.0 51 62 A D E -cd 24 88B 1 -28,-2.7 -26,-2.8 -2,-0.4 2,-0.6 -0.909 11.4-156.1-105.0 112.2 57.7 -6.2 -6.8 52 63 A I E -cd 25 89B 0 36,-3.3 38,-2.6 -2,-0.7 2,-0.4 -0.796 14.7-179.7 -93.4 121.7 59.7 -7.7 -9.5 53 64 A G E +c 26 0B 7 -28,-2.1 -26,-3.1 -2,-0.6 -25,-0.2 -0.987 19.8 177.1-127.6 123.2 58.7 -11.3 -10.3 54 65 A G S S+ 0 0 0 36,-0.5 2,-0.2 -2,-0.4 -1,-0.1 0.433 72.5 38.1 -99.2 -5.1 60.3 -13.5 -13.0 55 66 A E S S- 0 0 12 35,-0.4 2,-0.5 -27,-0.1 -27,-0.1 -0.495 92.9 -94.1-119.2-171.5 58.3 -16.7 -12.2 56 67 A S - 0 0 48 6,-0.5 2,-1.8 -2,-0.2 5,-0.1 -0.879 37.3-173.6-106.6 92.5 54.8 -17.7 -11.2 57 68 A T + 0 0 15 -2,-0.5 34,-0.0 33,-0.1 -2,-0.0 -0.579 48.8 103.7 -77.6 70.1 55.1 -17.8 -7.4 58 69 A R S > S- 0 0 145 -2,-1.8 3,-1.9 4,-0.1 -2,-0.1 -0.987 82.0 -75.3-152.9 153.5 51.6 -19.2 -7.0 59 70 A P T 3 S+ 0 0 44 0, 0.0 84,-0.1 0, 0.0 -2,-0.0 -0.200 115.2 9.0 -53.8 138.2 50.0 -22.6 -6.2 60 71 A G T 3 S+ 0 0 70 1,-0.2 83,-0.0 84,-0.0 0, 0.0 0.335 94.0 137.3 75.8 -6.5 49.9 -25.1 -9.2 61 72 A A < - 0 0 22 -3,-1.9 -1,-0.2 -5,-0.1 -3,-0.1 -0.510 57.5-118.1 -76.6 135.7 52.2 -22.8 -11.3 62 73 A P - 0 0 96 0, 0.0 -6,-0.5 0, 0.0 2,-0.1 -0.416 36.1-109.6 -68.6 150.0 55.0 -24.5 -13.3 63 74 A P - 0 0 98 0, 0.0 -6,-0.0 0, 0.0 -8,-0.0 -0.476 18.5-131.8 -84.6 154.5 58.6 -23.4 -12.2 64 75 A V - 0 0 20 -2,-0.1 -9,-0.0 1,-0.0 -10,-0.0 -0.850 30.4-109.1-100.9 136.4 61.0 -21.2 -14.2 65 76 A P >> - 0 0 70 0, 0.0 4,-2.0 0, 0.0 3,-0.8 -0.329 30.4-112.1 -66.2 150.6 64.6 -22.4 -14.6 66 77 A L H 3> S+ 0 0 67 1,-0.3 4,-2.5 2,-0.2 5,-0.2 0.862 112.8 50.1 -52.7 -51.1 67.3 -20.5 -12.7 67 78 A D H 3> S+ 0 0 126 1,-0.2 4,-1.8 2,-0.2 -1,-0.3 0.811 111.7 49.6 -63.8 -29.7 69.1 -18.9 -15.6 68 79 A E H <> S+ 0 0 101 -3,-0.8 4,-1.4 2,-0.2 -1,-0.2 0.894 110.1 49.5 -74.3 -41.0 65.8 -17.7 -17.2 69 80 A E H X S+ 0 0 0 -4,-2.0 4,-2.2 2,-0.2 5,-0.3 0.909 112.0 49.4 -63.1 -42.3 64.6 -16.1 -13.9 70 81 A L H X S+ 0 0 40 -4,-2.5 4,-2.0 1,-0.2 -2,-0.2 0.907 107.5 54.7 -62.5 -42.8 68.0 -14.4 -13.5 71 82 A A H < S+ 0 0 67 -4,-1.8 -1,-0.2 1,-0.2 -2,-0.2 0.799 115.2 40.1 -61.1 -30.4 67.8 -13.1 -17.1 72 83 A R H < S+ 0 0 54 -4,-1.4 4,-0.4 -3,-0.2 -2,-0.2 0.810 122.9 36.3 -84.8 -35.4 64.4 -11.5 -16.4 73 84 A V H X S+ 0 0 1 -4,-2.2 4,-2.4 -5,-0.2 3,-0.3 0.906 108.1 56.1 -91.3 -45.5 65.0 -10.1 -12.9 74 85 A I H X S+ 0 0 28 -4,-2.0 4,-2.7 -5,-0.3 5,-0.2 0.917 107.2 48.0 -62.8 -46.6 68.6 -8.9 -12.7 75 86 A P H > S+ 0 0 58 0, 0.0 4,-2.5 0, 0.0 -1,-0.2 0.829 112.2 52.2 -61.8 -28.8 68.5 -6.4 -15.7 76 87 A L H > S+ 0 0 3 -4,-0.4 4,-2.5 -3,-0.3 -2,-0.2 0.907 108.6 49.0 -72.8 -42.5 65.3 -5.0 -14.2 77 88 A V H X S+ 0 0 0 -4,-2.4 4,-1.6 2,-0.2 -1,-0.2 0.967 114.8 45.8 -57.7 -50.0 66.9 -4.5 -10.8 78 89 A E H < S+ 0 0 120 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.908 116.5 45.0 -59.3 -43.0 69.8 -2.8 -12.5 79 90 A A H < S+ 0 0 46 -4,-2.5 -1,-0.2 -5,-0.2 -2,-0.2 0.823 117.0 44.2 -72.0 -32.4 67.5 -0.6 -14.8 80 91 A L H >< S+ 0 0 2 -4,-2.5 3,-1.3 1,-0.2 5,-0.4 0.611 89.5 84.0 -90.9 -15.1 65.1 0.3 -11.9 81 92 A R G >< S+ 0 0 89 -4,-1.6 3,-2.1 1,-0.3 -1,-0.2 0.878 83.2 60.6 -58.8 -41.2 67.6 1.2 -9.2 82 93 A P G 3 S+ 0 0 105 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 0.722 90.1 70.9 -60.5 -18.7 68.1 4.8 -10.4 83 94 A L G < S- 0 0 72 -3,-1.3 -2,-0.2 -4,-0.1 -3,-0.1 0.628 98.5-137.8 -73.7 -12.6 64.4 5.5 -9.9 84 95 A N < + 0 0 107 -3,-2.1 -3,-0.1 -4,-0.3 -1,-0.1 0.857 57.4 128.0 60.5 40.2 65.1 5.4 -6.1 85 96 A V S S- 0 0 19 -5,-0.4 -1,-0.2 -4,-0.1 -36,-0.1 -0.959 72.1 -87.7-123.4 142.7 62.0 3.4 -5.2 86 97 A P - 0 0 8 0, 0.0 -36,-2.1 0, 0.0 2,-0.6 -0.240 40.6-151.8 -53.9 130.8 62.1 0.3 -3.1 87 98 A L E -d 50 0B 0 -38,-0.2 19,-2.0 17,-0.2 20,-2.0 -0.939 11.1-169.0-109.3 117.1 62.6 -2.8 -5.3 88 99 A S E -de 51 107B 0 -38,-3.1 -36,-3.3 -2,-0.6 2,-0.5 -0.779 11.6-144.6-102.7 145.3 61.2 -6.0 -3.9 89 100 A I E -de 52 108B 0 18,-2.3 20,-3.3 -2,-0.3 2,-1.3 -0.965 3.2-149.4-116.0 119.0 62.1 -9.4 -5.5 90 101 A D E + e 0 109B 7 -38,-2.6 -36,-0.5 -2,-0.5 -35,-0.4 -0.733 52.0 122.0 -88.3 89.3 59.4 -12.1 -5.6 91 102 A T - 0 0 0 18,-1.5 21,-0.1 -2,-1.3 -2,-0.1 -0.993 48.1-169.6-150.8 148.7 61.5 -15.2 -5.3 92 103 A Y + 0 0 11 -2,-0.3 24,-0.2 18,-0.2 27,-0.1 0.329 64.9 104.4-111.0 -2.2 62.0 -18.3 -3.2 93 104 A K >> - 0 0 30 1,-0.1 4,-2.5 26,-0.0 3,-0.8 -0.746 62.6-150.0 -89.6 116.0 65.2 -19.3 -4.9 94 105 A P H 3> S+ 0 0 29 0, 0.0 4,-2.9 0, 0.0 5,-0.2 0.845 97.6 56.1 -52.8 -35.0 68.4 -18.6 -2.8 95 106 A A H 3> S+ 0 0 45 2,-0.2 4,-2.1 1,-0.2 5,-0.1 0.879 109.5 45.5 -66.0 -36.8 70.5 -18.1 -6.0 96 107 A V H <> S+ 0 0 0 -3,-0.8 4,-2.9 2,-0.2 5,-0.3 0.916 112.0 52.5 -70.5 -42.3 68.0 -15.4 -7.2 97 108 A M H X S+ 0 0 0 -4,-2.5 4,-2.5 2,-0.2 5,-0.2 0.951 111.8 46.2 -54.2 -53.2 68.1 -13.9 -3.7 98 109 A R H X S+ 0 0 143 -4,-2.9 4,-1.9 1,-0.2 -1,-0.2 0.913 116.0 44.3 -52.7 -50.7 71.9 -13.7 -3.8 99 110 A A H X S+ 0 0 30 -4,-2.1 4,-1.6 2,-0.2 -1,-0.2 0.873 113.8 49.7 -69.9 -37.6 72.1 -12.3 -7.3 100 111 A A H X>S+ 0 0 0 -4,-2.9 5,-2.6 2,-0.2 4,-0.5 0.907 110.8 48.7 -70.3 -42.4 69.3 -9.7 -6.7 101 112 A L H ><5S+ 0 0 39 -4,-2.5 3,-0.8 -5,-0.3 -2,-0.2 0.902 110.7 51.5 -62.6 -39.9 70.8 -8.4 -3.5 102 113 A A H 3<5S+ 0 0 92 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.840 108.4 52.1 -65.5 -33.7 74.3 -8.1 -5.2 103 114 A A H 3<5S- 0 0 20 -4,-1.6 -1,-0.3 -5,-0.1 -2,-0.2 0.541 130.8 -98.5 -76.5 -10.7 72.5 -6.2 -8.0 104 115 A G T <<5 + 0 0 15 -3,-0.8 -3,-0.2 -4,-0.5 -93,-0.2 0.677 59.7 166.7 105.4 20.7 71.1 -3.9 -5.3 105 116 A A < - 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