==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=8-MAY-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 17-MAR-11 2YD2 . COMPND 2 MOLECULE: RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.H.COLES,Y.SHEN,A.P.TENNEY,C.SIEBOLD,G.C.SUTTON,W.LU,J.T.GA . 197 1 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10914.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 124 62.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 9 4.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 71 36.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 2.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 19 9.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 17 8.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 3 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 2 4 2 0 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 30 A E 0 0 172 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 87.7 -8.2 -4.2 11.0 2 31 A E E -A 30 0A 115 28,-0.8 28,-3.0 83,-0.0 82,-0.3 -0.898 360.0-122.2-104.7 135.4 -6.8 -5.0 7.5 3 32 A P E - 0 0 66 0, 0.0 25,-0.1 0, 0.0 78,-0.1 -0.286 44.6 -81.8 -65.4 159.2 -5.1 -2.3 5.4 4 33 A P E + 0 0 7 0, 0.0 2,-0.3 0, 0.0 25,-0.2 -0.296 50.2 179.6 -60.5 146.0 -6.5 -1.5 1.9 5 34 A R E -A 28 0A 143 23,-2.2 23,-3.0 -3,-0.1 2,-0.3 -0.971 28.0-113.4-148.2 139.5 -5.4 -3.8 -0.9 6 35 A F E +A 27 0A 25 -2,-0.3 21,-0.3 21,-0.3 3,-0.2 -0.523 26.0 177.6 -79.0 135.6 -6.4 -3.7 -4.6 7 36 A I E S+ 0 0 89 19,-2.4 2,-0.5 1,-0.4 20,-0.2 0.747 82.7 29.7-105.1 -34.6 -8.5 -6.5 -6.1 8 37 A K E S-A 26 0A 98 18,-1.4 18,-2.2 0, 0.0 -1,-0.4 -0.974 81.1-164.0-118.7 116.9 -8.8 -5.0 -9.6 9 38 A E - 0 0 96 -2,-0.5 16,-0.1 16,-0.2 15,-0.1 -0.809 22.4-109.7 -98.4 140.6 -5.8 -2.8 -10.5 10 39 A P - 0 0 11 0, 0.0 2,-0.3 0, 0.0 80,-0.1 -0.196 29.8-147.4 -63.2 154.8 -5.9 -0.4 -13.5 11 40 A K - 0 0 127 80,-0.1 80,-0.1 81,-0.0 13,-0.1 -0.934 28.5 -89.9-125.6 149.1 -3.8 -1.0 -16.6 12 41 A D - 0 0 98 -2,-0.3 2,-0.4 78,-0.1 81,-0.2 -0.306 47.3-149.7 -53.4 135.8 -2.1 1.3 -19.0 13 42 A Q E -d 93 0B 33 79,-2.5 81,-2.9 172,-0.0 2,-0.6 -0.939 17.1-160.6-118.2 135.0 -4.5 2.3 -21.8 14 43 A I E +d 94 0B 55 -2,-0.4 172,-3.0 79,-0.2 81,-0.2 -0.929 29.7 175.7-108.2 104.6 -3.8 3.2 -25.4 15 44 A G E -d 95 0B 0 79,-3.1 81,-2.9 -2,-0.6 2,-0.4 -0.582 29.3-110.2-107.9 168.1 -6.9 5.1 -26.6 16 45 A V E > -d 96 0B 7 170,-0.4 3,-2.1 4,-0.3 51,-0.4 -0.832 37.0-104.0-101.0 134.9 -7.9 6.9 -29.8 17 46 A S T 3 S+ 0 0 37 79,-3.8 51,-0.2 -2,-0.4 81,-0.2 -0.327 110.6 25.4 -51.2 126.8 -8.2 10.7 -30.1 18 47 A G T 3 S+ 0 0 46 49,-2.7 -1,-0.3 1,-0.3 50,-0.1 0.469 112.9 82.5 93.2 4.7 -12.0 11.5 -30.1 19 48 A G S < S- 0 0 24 -3,-2.1 48,-1.3 48,-0.1 2,-0.3 -0.168 78.8 -79.2-116.8-150.3 -13.0 8.3 -28.3 20 49 A V - 0 0 13 46,-0.2 2,-0.3 45,-0.1 -4,-0.3 -0.884 28.3-178.3-121.9 150.4 -13.2 6.8 -24.8 21 50 A A E - B 0 64A 0 43,-1.4 43,-2.6 -2,-0.3 2,-0.4 -0.981 8.0-168.1-143.7 140.1 -10.8 5.4 -22.3 22 51 A S E - B 0 63A 6 -2,-0.3 2,-0.5 41,-0.2 41,-0.2 -0.995 10.2-159.4-131.3 136.5 -11.6 3.9 -18.8 23 52 A F E - B 0 62A 1 39,-2.6 39,-2.8 -2,-0.4 2,-0.5 -0.965 14.9-153.7-110.1 124.7 -9.4 2.9 -15.9 24 53 A V E + B 0 61A 14 -2,-0.5 2,-0.4 37,-0.2 37,-0.2 -0.854 17.3 173.3-102.4 129.9 -11.0 0.5 -13.4 25 54 A a E + B 0 60A 0 35,-1.8 35,-3.3 -2,-0.5 2,-0.3 -0.995 3.7 161.2-138.0 130.3 -9.8 0.5 -9.7 26 55 A Q E -AB 8 59A 37 -18,-2.2 -19,-2.4 -2,-0.4 -18,-1.4 -0.996 9.5-174.7-148.8 144.9 -11.1 -1.4 -6.7 27 56 A A E -A 6 0A 0 31,-2.9 2,-0.3 -2,-0.3 -21,-0.3 -0.853 10.3-150.8-133.6 168.2 -9.8 -2.4 -3.3 28 57 A T E +A 5 0A 44 -23,-3.0 -23,-2.2 -2,-0.3 2,-0.3 -0.931 30.4 122.5-133.7 160.5 -10.7 -4.4 -0.1 29 58 A G E - 0 0 16 -2,-0.3 3,-0.1 -25,-0.2 52,-0.0 -0.969 55.3 -58.0 177.3-163.8 -9.8 -4.0 3.6 30 59 A D E S+A 2 0A 90 -28,-3.0 -28,-0.8 1,-0.3 2,-0.2 -0.790 124.6 26.5-153.9 108.7 -11.1 -3.7 7.1 31 60 A P S S- 0 0 57 0, 0.0 -1,-0.3 0, 0.0 53,-0.2 0.533 124.2 -91.4 -66.1 167.8 -12.7 -1.3 7.6 32 61 A K - 0 0 89 -2,-0.2 -2,-0.1 -3,-0.1 51,-0.1 -0.247 47.9-122.4 -55.5 133.2 -13.8 -1.2 3.9 33 62 A P - 0 0 3 0, 0.0 2,-0.5 0, 0.0 49,-0.2 -0.362 11.6-140.3 -79.1 155.7 -11.5 1.1 1.9 34 63 A R E -E 81 0C 141 47,-2.4 47,-1.1 24,-0.1 2,-0.3 -0.981 18.5-156.3-116.1 124.7 -12.5 4.1 -0.1 35 64 A V E +E 80 0C 3 22,-2.2 2,-0.3 -2,-0.5 45,-0.2 -0.690 13.9 174.9-101.1 154.9 -10.8 4.6 -3.5 36 65 A T E -E 79 0C 43 43,-1.3 43,-2.8 -2,-0.3 2,-0.4 -0.988 23.0-126.2-153.1 154.1 -10.3 7.8 -5.5 37 66 A W E +E 78 0C 1 -2,-0.3 7,-0.8 41,-0.2 2,-0.3 -0.843 30.6 161.4-106.6 140.6 -8.5 9.0 -8.6 38 67 A N E -EF 77 43C 19 39,-2.4 39,-2.9 -2,-0.4 2,-0.5 -0.934 30.6-130.1-143.4 171.5 -6.1 11.9 -9.0 39 68 A K E > S-EF 76 42C 81 3,-2.8 3,-0.6 -2,-0.3 37,-0.1 -0.966 81.5 -27.0-128.1 115.4 -3.4 13.1 -11.4 40 69 A K T 3 S- 0 0 186 35,-0.5 2,-1.5 -2,-0.5 -1,-0.1 0.911 122.7 -52.0 51.7 50.5 0.1 14.0 -10.2 41 70 A G T 3 S+ 0 0 60 1,-0.1 -1,-0.3 36,-0.0 0, 0.0 -0.433 123.3 91.3 89.1 -63.8 -1.2 14.9 -6.7 42 71 A K E < S-F 39 0C 158 -2,-1.5 -3,-2.8 -3,-0.6 2,-0.2 -0.304 85.1-106.8 -62.5 150.7 -3.9 17.3 -7.6 43 72 A K E -F 38 0C 132 -5,-0.3 -5,-0.2 1,-0.1 2,-0.2 -0.534 41.8 -83.5 -88.5 151.8 -7.3 15.7 -8.1 44 73 A V + 0 0 29 -7,-0.8 2,-0.3 -2,-0.2 -1,-0.1 -0.279 52.9 170.3 -59.5 117.2 -9.0 15.1 -11.5 45 74 A N + 0 0 143 -2,-0.2 2,-0.3 -3,-0.1 -1,-0.1 -0.668 23.1 114.0-135.8 81.2 -10.8 18.3 -12.6 46 75 A S > - 0 0 51 -2,-0.3 3,-0.7 3,-0.3 -2,-0.0 -0.971 64.6-124.2-146.1 159.3 -12.1 18.4 -16.2 47 76 A Q T 3 S+ 0 0 196 -2,-0.3 -1,-0.0 1,-0.2 -2,-0.0 0.633 114.5 48.5 -77.6 -13.7 -15.4 18.5 -18.0 48 77 A R T 3 S+ 0 0 51 16,-0.0 17,-2.1 18,-0.0 2,-0.4 0.375 96.9 85.4-106.6 -0.1 -14.4 15.4 -19.9 49 78 A F E < +C 64 0A 31 -3,-0.7 2,-0.4 15,-0.2 -3,-0.3 -0.893 54.2 178.5-107.9 133.6 -13.3 13.4 -16.9 50 79 A E E -C 63 0A 93 13,-2.5 13,-2.9 -2,-0.4 2,-0.5 -0.989 19.5-154.7-136.9 141.7 -15.7 11.4 -14.8 51 80 A T E -C 62 0A 52 -2,-0.4 2,-0.7 11,-0.2 11,-0.2 -0.971 10.6-167.8-114.8 117.4 -15.4 9.1 -11.8 52 81 A I E -C 61 0A 28 9,-2.4 9,-2.3 -2,-0.5 2,-0.1 -0.930 14.5-150.2-107.0 112.5 -18.2 6.6 -11.4 53 82 A E E +C 60 0A 103 -2,-0.7 2,-0.3 7,-0.2 7,-0.3 -0.382 22.1 163.9 -79.4 156.2 -18.1 5.0 -7.9 54 83 A F E > +C 59 0A 50 5,-2.8 5,-1.7 1,-0.1 3,-0.5 -0.957 47.8 48.6-158.8 177.5 -19.2 1.4 -7.1 55 84 A D T > 5S- 0 0 62 -2,-0.3 3,-2.3 1,-0.2 -1,-0.1 0.942 132.5 -53.7 47.8 55.4 -18.9 -1.3 -4.4 56 85 A E T 3 5S- 0 0 160 1,-0.3 -1,-0.2 2,-0.1 -3,-0.0 0.812 106.1 -53.8 51.0 36.8 -19.8 1.2 -1.7 57 86 A S T 3 5S+ 0 0 18 -3,-0.5 -22,-2.2 2,-0.3 -1,-0.3 0.508 117.9 109.8 79.2 5.9 -17.0 3.5 -2.9 58 87 A A T < 5S+ 0 0 0 -3,-2.3 -31,-2.9 -4,-0.5 2,-0.3 0.349 80.6 48.5 -88.3 3.4 -14.4 0.8 -2.6 59 88 A G E < +BC 26 54A 0 -5,-1.7 -5,-2.8 -33,-0.3 2,-0.4 -0.998 65.3 179.2-144.2 140.6 -14.3 0.9 -6.4 60 89 A A E -BC 25 53A 1 -35,-3.3 -35,-1.8 -2,-0.3 2,-0.5 -0.989 14.7-154.2-146.4 134.6 -14.0 3.7 -8.9 61 90 A V E -BC 24 52A 0 -9,-2.3 -9,-2.4 -2,-0.4 2,-0.6 -0.899 10.6-152.2-104.3 131.2 -13.9 3.9 -12.7 62 91 A L E -BC 23 51A 0 -39,-2.8 -39,-2.6 -2,-0.5 2,-0.4 -0.929 18.6-174.0-102.5 121.0 -12.2 6.9 -14.3 63 92 A R E -BC 22 50A 6 -13,-2.9 -13,-2.5 -2,-0.6 2,-0.5 -0.960 8.0-167.7-120.5 134.2 -13.7 7.6 -17.7 64 93 A I E -BC 21 49A 0 -43,-2.6 -43,-1.4 -2,-0.4 3,-0.2 -0.982 10.0-162.7-123.4 124.2 -12.5 10.2 -20.3 65 94 A Q S S+ 0 0 89 -17,-2.1 -45,-0.1 -2,-0.5 2,-0.1 -0.924 70.9 23.2-158.8 137.9 -14.4 11.3 -23.3 66 95 A P S S- 0 0 54 0, 0.0 -1,-0.4 0, 0.0 2,-0.3 0.628 88.4-137.1 -73.1 153.0 -13.7 12.7 -25.8 67 96 A L - 0 0 0 -48,-1.3 -49,-2.7 -51,-0.4 2,-0.4 -0.593 22.3-166.1 -74.5 135.2 -10.0 11.6 -25.6 68 97 A R > - 0 0 98 -2,-0.3 4,-2.6 -51,-0.2 5,-0.4 -0.987 13.0-118.2-129.0 132.8 -7.7 14.5 -26.5 69 98 A T T 4 S+ 0 0 37 -2,-0.4 27,-0.0 1,-0.2 25,-0.0 -0.926 84.3 2.5-121.0 144.5 -3.9 14.3 -27.3 70 99 A P T >4 S+ 0 0 102 0, 0.0 3,-0.8 0, 0.0 -1,-0.2 -0.998 125.7 60.7 -79.9 -5.7 -1.5 15.4 -26.1 71 100 A R T 34 S+ 0 0 177 1,-0.3 -2,-0.2 -4,-0.0 -4,-0.0 0.790 106.6 43.7 -56.5 -37.5 -3.5 17.0 -23.2 72 101 A D T 3< S+ 0 0 4 -4,-2.6 2,-0.4 2,-0.0 -1,-0.3 0.763 83.9 108.4 -80.2 -25.9 -5.0 13.8 -21.7 73 102 A E < + 0 0 66 -3,-0.8 2,-0.3 -5,-0.4 21,-0.2 -0.377 50.8 113.9 -58.9 112.0 -1.8 11.7 -21.9 74 103 A N S S- 0 0 50 19,-0.4 19,-3.2 -2,-0.4 2,-0.5 -0.881 70.6 -88.6-158.3-177.8 -0.7 11.4 -18.3 75 104 A V E - G 0 92C 69 -2,-0.3 -35,-0.5 17,-0.2 2,-0.3 -0.964 42.3-155.4-107.5 126.5 -0.2 9.0 -15.4 76 105 A Y E -EG 39 91C 2 15,-3.5 15,-2.5 -2,-0.5 2,-0.5 -0.815 3.2-147.3-109.8 146.7 -3.3 8.6 -13.4 77 106 A E E -EG 38 90C 52 -39,-2.9 -39,-2.4 -2,-0.3 2,-0.5 -0.938 7.8-162.0-125.0 126.5 -3.3 7.5 -9.7 78 107 A a E -EG 37 89C 0 11,-2.7 11,-2.1 -2,-0.5 2,-0.5 -0.921 12.8-162.6-105.4 127.9 -5.8 5.4 -7.7 79 108 A V E -EG 36 88C 11 -43,-2.8 -43,-1.3 -2,-0.5 2,-0.4 -0.937 4.5-164.5-116.1 126.3 -5.6 5.7 -4.0 80 109 A A E +EG 35 87C 0 7,-2.9 7,-2.1 -2,-0.5 2,-0.3 -0.917 20.1 172.7-108.8 135.3 -7.2 3.2 -1.6 81 110 A Q E +EG 34 86C 111 -47,-1.1 -47,-2.4 -2,-0.4 2,-0.2 -0.998 14.5 150.3-150.0 141.5 -7.6 4.2 2.1 82 111 A N - 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