==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=24-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSCRIPTION 26-APR-11 2YH0 . COMPND 2 MOLECULE: SPLICING FACTOR U2AF 65 KDA SUBUNIT; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.D.MACKERETH,T.MADL,B.SIMON,K.ZANIER,A.GASCH,M.SATTLER . 195 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11919.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 127 65.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 48 24.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 25 12.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 16 8.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 31 15.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 0 0 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 1 2 1 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 148 A A 0 0 111 0, 0.0 53,-0.0 0, 0.0 80,-0.0 0.000 360.0 360.0 360.0 -71.2 -21.2 -7.5 10.7 2 149 A R + 0 0 122 59,-0.1 53,-3.0 2,-0.1 2,-0.4 0.247 360.0 93.8-117.7 9.4 -23.1 -5.9 7.8 3 150 A R E -A 54 0A 80 51,-0.3 2,-0.3 49,-0.0 51,-0.3 -0.883 61.7-149.5-106.9 133.2 -20.4 -6.5 5.2 4 151 A L E -A 53 0A 8 49,-2.2 49,-1.6 -2,-0.4 2,-0.8 -0.735 14.2-128.7 -97.2 150.4 -20.4 -9.5 2.9 5 152 A Y E -AB 52 80A 56 75,-2.9 75,-2.9 -2,-0.3 2,-0.5 -0.871 29.6-177.8-100.7 105.3 -17.3 -11.1 1.5 6 153 A V E +AB 51 79A 0 45,-2.5 45,-2.5 -2,-0.8 73,-0.2 -0.908 8.0 166.8-107.7 129.3 -17.6 -11.5 -2.2 7 154 A G E +AB 50 78A 4 71,-2.3 71,-2.6 -2,-0.5 43,-0.2 -0.711 46.6 60.3-129.7-177.5 -14.8 -13.2 -4.2 8 155 A N S S+ 0 0 79 41,-0.8 68,-0.3 -2,-0.2 -1,-0.1 0.863 74.7 169.6 61.8 38.8 -14.1 -14.6 -7.6 9 156 A I - 0 0 1 40,-0.3 2,-0.4 -3,-0.2 -1,-0.2 -0.458 40.9 -97.4 -84.3 152.3 -14.9 -11.2 -9.0 10 157 A P > - 0 0 12 0, 0.0 3,-0.9 0, 0.0 2,-0.7 -0.555 33.3-130.5 -71.3 123.1 -14.2 -10.1 -12.7 11 158 A F T 3 S+ 0 0 162 -2,-0.4 3,-0.1 1,-0.2 36,-0.0 -0.658 93.2 32.2 -75.9 113.7 -11.0 -8.2 -13.1 12 159 A G T 3 S+ 0 0 61 -2,-0.7 -1,-0.2 1,-0.5 34,-0.0 -0.062 87.7 112.7 132.2 -33.5 -11.8 -5.1 -15.0 13 160 A I < - 0 0 37 -3,-0.9 -1,-0.5 1,-0.1 2,-0.2 -0.304 65.3-116.2 -71.3 153.9 -15.3 -4.3 -13.9 14 161 A T > - 0 0 84 1,-0.1 4,-2.0 -3,-0.1 5,-0.2 -0.497 13.6-122.3 -88.9 161.1 -16.1 -1.2 -11.8 15 162 A E H > S+ 0 0 89 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.881 113.6 56.3 -66.1 -37.9 -17.4 -1.1 -8.3 16 163 A E H > S+ 0 0 116 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.920 108.2 45.3 -59.2 -48.8 -20.3 1.0 -9.5 17 164 A A H > S+ 0 0 35 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.917 114.6 47.4 -64.9 -44.2 -21.4 -1.6 -12.1 18 165 A M H X S+ 0 0 0 -4,-2.0 4,-2.2 2,-0.2 -1,-0.2 0.898 111.5 51.7 -65.1 -39.9 -21.0 -4.5 -9.6 19 166 A M H X S+ 0 0 12 -4,-2.6 4,-3.0 2,-0.2 -2,-0.2 0.927 109.9 48.3 -62.3 -46.2 -23.0 -2.6 -7.0 20 167 A D H X S+ 0 0 103 -4,-2.3 4,-2.9 1,-0.2 -1,-0.2 0.881 108.3 56.3 -61.7 -38.6 -25.8 -1.9 -9.4 21 168 A F H X S+ 0 0 49 -4,-2.1 4,-2.1 2,-0.2 -1,-0.2 0.932 111.3 42.5 -57.6 -48.2 -25.8 -5.6 -10.4 22 169 A F H X S+ 0 0 7 -4,-2.2 4,-2.7 2,-0.2 -2,-0.2 0.935 113.0 52.6 -64.5 -47.2 -26.3 -6.6 -6.7 23 170 A N H X S+ 0 0 6 -4,-3.0 4,-2.1 1,-0.2 -2,-0.2 0.914 110.4 48.6 -54.9 -46.3 -28.9 -3.8 -6.1 24 171 A A H X S+ 0 0 31 -4,-2.9 4,-3.3 1,-0.2 5,-0.3 0.932 111.6 48.6 -59.5 -47.7 -30.9 -5.0 -9.1 25 172 A Q H X S+ 0 0 52 -4,-2.1 4,-2.2 1,-0.2 6,-0.3 0.873 109.3 53.6 -62.3 -37.7 -30.8 -8.6 -8.0 26 173 A M H X>S+ 0 0 1 -4,-2.7 5,-2.7 2,-0.2 6,-1.5 0.911 115.5 40.0 -62.6 -42.3 -31.9 -7.6 -4.5 27 174 A R H ><5S+ 0 0 113 -4,-2.1 3,-0.7 3,-0.2 -2,-0.2 0.966 117.5 45.6 -71.2 -52.8 -34.9 -5.8 -5.9 28 175 A L H 3<5S+ 0 0 141 -4,-3.3 -2,-0.2 1,-0.3 -3,-0.2 0.819 115.7 46.9 -64.6 -34.1 -35.9 -8.3 -8.6 29 176 A G H 3<5S- 0 0 54 -4,-2.2 -1,-0.3 -5,-0.3 -2,-0.2 0.673 112.8-117.4 -81.9 -16.8 -35.5 -11.2 -6.3 30 177 A G T <<5S+ 0 0 58 -4,-0.7 -3,-0.2 -3,-0.7 -4,-0.1 0.787 75.6 129.7 84.1 29.8 -37.5 -9.5 -3.5 31 178 A L < + 0 0 14 -5,-2.7 2,-0.2 -6,-0.3 -4,-0.2 0.658 42.8 102.2 -86.9 -18.8 -34.6 -9.5 -1.1 32 179 A T - 0 0 38 -6,-1.5 4,-0.0 1,-0.2 5,-0.0 -0.478 50.4-171.0 -69.3 128.2 -35.1 -5.8 -0.4 33 180 A Q S S+ 0 0 117 -2,-0.2 -1,-0.2 1,-0.2 -2,-0.0 0.396 80.8 19.5 -94.1 -1.0 -36.9 -5.0 2.9 34 181 A A S S- 0 0 37 2,-0.1 -1,-0.2 0, 0.0 -3,-0.0 -0.974 90.9 -94.6-160.1 155.4 -37.1 -1.4 1.7 35 182 A P S S+ 0 0 120 0, 0.0 2,-0.4 0, 0.0 -2,-0.1 -0.144 85.4 35.8 -66.7 168.8 -36.9 0.5 -1.6 36 183 A G S S- 0 0 15 -4,-0.0 -9,-0.1 2,-0.0 -2,-0.1 -0.696 110.8 -18.6 93.9-138.6 -33.7 2.1 -2.9 37 184 A N - 0 0 30 -2,-0.4 19,-0.1 1,-0.1 -17,-0.0 -0.949 41.8-164.4-116.4 118.1 -30.3 0.6 -2.4 38 185 A P S S+ 0 0 0 0, 0.0 18,-3.0 0, 0.0 2,-0.4 0.767 74.5 84.8 -66.6 -26.5 -29.7 -2.1 0.3 39 186 A V E -C 55 0A 3 16,-0.3 16,-0.3 1,-0.2 3,-0.2 -0.668 53.4-179.4 -82.5 127.3 -26.0 -1.5 -0.0 40 187 A L E S+ 0 0 30 14,-3.1 96,-1.4 -2,-0.4 2,-0.4 0.822 73.4 15.4 -91.8 -40.4 -24.7 1.3 2.1 41 188 A A E -CD 54 135A 1 13,-2.2 13,-2.9 94,-0.2 2,-0.7 -0.964 62.7-157.3-143.3 121.2 -21.0 1.1 1.1 42 189 A V E +C 53 0A 16 92,-0.6 2,-0.5 -2,-0.4 11,-0.2 -0.877 18.9 170.6 -98.4 115.4 -19.4 -0.7 -1.8 43 190 A Q E -C 52 0A 36 9,-1.3 9,-3.1 -2,-0.7 2,-0.5 -0.917 6.2-179.8-128.7 106.4 -15.8 -1.4 -1.2 44 191 A I E -C 51 0A 23 -2,-0.5 2,-0.8 7,-0.3 7,-0.3 -0.920 17.7-163.5-114.0 123.1 -14.1 -3.7 -3.8 45 192 A N E > +C 50 0A 59 5,-2.4 5,-2.9 -2,-0.5 4,-0.1 -0.868 15.5 170.8-100.5 99.6 -10.5 -4.8 -3.7 46 193 A Q T 5 + 0 0 47 -2,-0.8 -1,-0.2 3,-0.2 5,-0.1 0.668 68.9 71.2 -85.5 -16.9 -9.9 -6.1 -7.2 47 194 A D T 5S+ 0 0 116 1,-0.2 -1,-0.2 -3,-0.1 -2,-0.0 0.928 115.3 22.9 -62.6 -47.6 -6.2 -6.4 -6.7 48 195 A K T 5S- 0 0 137 2,-0.2 -1,-0.2 -3,-0.1 -2,-0.2 0.254 113.5-116.6-105.6 9.0 -6.6 -9.4 -4.3 49 196 A N T 5S+ 0 0 56 1,-0.2 -41,-0.8 -4,-0.1 2,-0.3 0.904 74.9 112.7 62.0 48.6 -10.0 -10.2 -5.8 50 197 A F E < -AC 7 45A 47 -5,-2.9 -5,-2.4 -43,-0.2 2,-0.3 -0.989 41.3-169.3-148.2 142.8 -12.2 -9.7 -2.8 51 198 A A E -AC 6 44A 0 -45,-2.5 -45,-2.5 -2,-0.3 2,-0.6 -0.966 15.2-146.2-134.3 150.5 -14.8 -7.2 -1.9 52 199 A F E -AC 5 43A 57 -9,-3.1 -9,-1.3 -2,-0.3 2,-0.7 -0.943 13.3-164.9-117.4 108.5 -16.8 -6.1 1.2 53 200 A L E -AC 4 42A 2 -49,-1.6 -49,-2.2 -2,-0.6 2,-0.6 -0.845 7.8-156.1 -94.9 114.5 -20.3 -5.0 0.5 54 201 A E E -AC 3 41A 40 -13,-2.9 -14,-3.1 -2,-0.7 -13,-2.2 -0.814 11.8-158.0 -94.1 119.5 -21.7 -3.2 3.5 55 202 A F E - C 0 39A 1 -53,-3.0 -16,-0.3 -2,-0.6 -53,-0.0 -0.499 28.1-118.2 -94.1 164.2 -25.5 -3.2 3.7 56 203 A R S S+ 0 0 68 -18,-3.0 2,-0.2 -2,-0.2 -17,-0.1 0.579 98.8 14.8 -73.3 -11.6 -27.9 -0.9 5.5 57 204 A S - 0 0 13 -19,-0.4 -2,-0.3 -55,-0.2 -17,-0.1 -0.660 69.6-123.4-141.7-166.8 -29.1 -3.9 7.5 58 205 A V S > S+ 0 0 59 -2,-0.2 4,-2.7 3,-0.1 5,-0.2 0.567 102.2 63.2-116.6 -30.9 -28.1 -7.5 8.5 59 206 A D H > S+ 0 0 89 2,-0.2 4,-2.1 1,-0.2 5,-0.2 0.973 107.8 39.9 -57.6 -60.4 -31.3 -9.1 7.3 60 207 A E H > S+ 0 0 1 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.894 113.4 58.1 -58.9 -40.3 -30.9 -8.3 3.6 61 208 A T H > S+ 0 0 5 1,-0.2 4,-0.6 2,-0.2 3,-0.2 0.941 108.2 44.4 -52.5 -52.1 -27.2 -9.0 3.9 62 209 A T H >< S+ 0 0 71 -4,-2.7 3,-0.8 1,-0.2 -1,-0.2 0.860 112.5 53.4 -63.0 -34.2 -27.9 -12.5 5.1 63 210 A Q H >< S+ 0 0 100 -4,-2.1 3,-1.5 1,-0.2 -1,-0.2 0.840 100.5 60.7 -71.2 -30.9 -30.5 -12.9 2.3 64 211 A A H >< S+ 0 0 1 -4,-2.3 3,-1.6 1,-0.3 -1,-0.2 0.665 85.4 77.9 -72.1 -15.0 -28.0 -11.8 -0.3 65 212 A M G X< S+ 0 0 43 -3,-0.8 3,-1.4 -4,-0.6 -1,-0.3 0.683 75.7 77.0 -68.3 -16.0 -25.9 -14.8 0.6 66 213 A A G < S+ 0 0 78 -3,-1.5 -1,-0.3 1,-0.3 -2,-0.2 0.715 83.7 65.0 -66.6 -20.3 -28.3 -17.0 -1.4 67 214 A F G X + 0 0 53 -3,-1.6 3,-2.1 -4,-0.1 2,-0.6 0.116 67.1 143.9 -93.0 21.5 -26.6 -15.7 -4.6 68 215 A D T < S+ 0 0 55 -3,-1.4 10,-0.2 1,-0.3 9,-0.1 -0.495 74.6 23.4 -61.2 109.0 -23.3 -17.3 -3.7 69 216 A G T 3 S+ 0 0 35 8,-3.5 -1,-0.3 -2,-0.6 9,-0.2 0.547 86.8 164.7 107.0 13.3 -22.1 -18.4 -7.1 70 217 A I E < -E 77 0B 20 -3,-2.1 7,-2.5 7,-1.0 2,-0.7 -0.336 42.2-112.8 -66.4 141.8 -24.1 -15.9 -9.2 71 218 A I E +E 76 0B 119 5,-0.2 2,-0.4 -2,-0.0 5,-0.2 -0.670 44.9 165.1 -82.5 114.1 -23.0 -15.4 -12.8 72 219 A F E > -E 75 0B 10 3,-3.1 3,-2.0 -2,-0.7 -54,-0.0 -0.946 68.8 -25.6-135.3 112.8 -21.5 -11.9 -13.3 73 220 A Q T 3 S- 0 0 136 -2,-0.4 3,-0.1 1,-0.3 -60,-0.1 0.782 125.2 -50.8 59.6 31.4 -19.5 -11.0 -16.4 74 221 A G T 3 S+ 0 0 59 1,-0.4 -1,-0.3 -64,-0.1 2,-0.1 0.057 122.3 100.4 96.5 -24.8 -18.5 -14.6 -16.9 75 222 A Q E < S-E 72 0B 79 -3,-2.0 -3,-3.1 -4,-0.0 2,-0.6 -0.439 72.2-125.9 -91.9 167.3 -17.3 -15.0 -13.3 76 223 A S E -E 71 0B 54 -68,-0.3 2,-0.4 -5,-0.2 -5,-0.2 -0.892 24.8-137.4-118.1 99.8 -19.1 -16.7 -10.4 77 224 A L E -E 70 0B 0 -7,-2.5 -8,-3.5 -2,-0.6 -7,-1.0 -0.392 13.5-147.5 -66.1 112.9 -19.4 -14.3 -7.5 78 225 A K E -B 7 0A 107 -71,-2.6 -71,-2.3 -2,-0.4 2,-0.6 -0.700 11.9-163.6 -81.8 124.7 -18.7 -16.2 -4.3 79 226 A I E +B 6 0A 2 -2,-0.5 2,-0.3 -73,-0.2 -73,-0.2 -0.910 26.0 140.4-118.8 106.2 -20.6 -14.8 -1.4 80 227 A R E -B 5 0A 126 -75,-2.9 -75,-2.9 -2,-0.6 -2,-0.0 -0.819 55.3 -85.7-134.5 171.6 -19.5 -15.7 2.1 81 228 A R - 0 0 150 -2,-0.3 -77,-0.1 -77,-0.2 -2,-0.0 -0.689 51.6-110.7 -83.6 135.0 -19.1 -14.2 5.5 82 229 A P - 0 0 40 0, 0.0 -1,-0.1 0, 0.0 2,-0.1 -0.027 34.9 -97.3 -60.3 165.9 -15.7 -12.3 6.1 83 230 A H - 0 0 156 1,-0.1 2,-1.1 0, 0.0 0, 0.0 -0.311 46.9 -85.0 -79.6 165.8 -13.0 -13.6 8.4 84 231 A D + 0 0 161 -2,-0.1 2,-0.4 2,-0.0 -1,-0.1 -0.639 64.1 165.9 -73.0 102.2 -12.5 -12.3 12.0 85 232 A Y - 0 0 163 -2,-1.1 0, 0.0 2,-0.0 0, 0.0 -0.986 23.1-164.6-126.3 131.1 -10.4 -9.3 11.4 86 233 A Q - 0 0 144 -2,-0.4 2,-0.5 3,-0.0 -2,-0.0 -0.961 28.0-120.6-113.3 124.7 -9.6 -6.5 13.8 87 234 A P - 0 0 105 0, 0.0 -2,-0.0 0, 0.0 0, 0.0 -0.527 33.0-124.7 -61.9 114.4 -8.2 -3.2 12.5 88 235 A L - 0 0 85 -2,-0.5 -3,-0.0 1,-0.1 2,-0.0 -0.522 31.9-159.8 -68.7 114.8 -4.9 -2.8 14.3 89 236 A P - 0 0 104 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.065 15.1-102.8 -83.5-172.3 -4.9 0.5 16.1 90 237 A G - 0 0 33 1,-0.2 4,-0.2 4,-0.1 13,-0.0 -0.854 13.1-161.1-118.2 153.4 -2.0 2.6 17.3 91 238 A M S S- 0 0 174 -2,-0.3 -1,-0.2 0, 0.0 3,-0.1 0.889 94.2 -24.0 -92.9 -57.4 -0.5 3.1 20.8 92 239 A S S S+ 0 0 119 2,-0.0 2,-0.2 0, 0.0 -2,-0.0 0.116 138.6 15.9-136.8 15.5 1.5 6.3 20.2 93 240 A E S S- 0 0 110 -4,-0.0 4,-0.1 0, 0.0 3,-0.0 -0.820 91.4 -75.6-162.1-169.1 1.9 5.8 16.5 94 241 A N - 0 0 62 -2,-0.2 -4,-0.1 2,-0.2 4,-0.1 -0.918 32.4-126.2-108.4 141.9 0.6 3.9 13.5 95 242 A P S S- 0 0 70 0, 0.0 -1,-0.1 0, 0.0 -5,-0.1 0.869 95.7 -36.8 -49.6 -38.7 1.5 0.2 13.0 96 243 A S S S- 0 0 107 -3,-0.0 -2,-0.2 0, 0.0 0, 0.0 0.155 94.8 -76.4-146.2 -75.6 2.6 1.4 9.5 97 244 A V + 0 0 83 -4,-0.1 2,-1.4 3,-0.0 0, 0.0 0.282 46.1 178.6-160.8 -44.7 0.4 4.2 8.0 98 245 A Y - 0 0 112 2,-0.1 -4,-0.0 -4,-0.1 0, 0.0 -0.523 68.3 -28.7 63.4 -90.7 -2.9 2.9 6.6 99 246 A V > - 0 0 58 -2,-1.4 3,-1.8 3,-0.1 2,-1.0 -0.943 59.6-111.3-160.6 128.4 -4.4 6.1 5.4 100 247 A P T 3 S+ 0 0 119 0, 0.0 3,-0.1 0, 0.0 -2,-0.1 -0.522 105.0 56.8 -62.5 100.8 -4.0 9.8 6.5 101 248 A G T 3 S+ 0 0 18 -2,-1.0 3,-0.4 1,-0.6 2,-0.3 0.146 81.6 91.8 157.6 -23.8 -7.5 10.3 7.9 102 249 A V S < S+ 0 0 29 -3,-1.8 -1,-0.6 1,-0.2 -3,-0.1 -0.789 98.2 6.5 -97.3 142.5 -7.9 7.6 10.5 103 250 A V S S+ 0 0 106 -2,-0.3 -1,-0.2 2,-0.2 3,-0.1 0.695 102.6 104.5 61.3 19.5 -7.0 8.3 14.2 104 251 A S + 0 0 75 -3,-0.4 2,-1.1 1,-0.2 3,-0.2 0.702 61.7 72.4 -98.1 -25.4 -6.5 12.0 13.1 105 252 A T + 0 0 62 -4,-0.3 -1,-0.2 1,-0.2 -2,-0.2 -0.755 48.2 151.5 -94.8 91.7 -9.7 13.2 14.6 106 253 A V + 0 0 128 -2,-1.1 -1,-0.2 3,-0.1 4,-0.1 0.657 65.3 55.0 -92.2 -20.3 -9.1 13.1 18.3 107 254 A V S S- 0 0 81 2,-0.3 -3,-0.0 -3,-0.2 0, 0.0 -0.776 88.9-119.1-109.8 156.1 -11.6 15.9 18.9 108 255 A P S S+ 0 0 136 0, 0.0 2,-0.5 0, 0.0 -1,-0.1 0.808 93.3 93.7 -61.1 -31.6 -15.3 16.2 17.9 109 256 A D + 0 0 140 2,-0.1 2,-0.3 -3,-0.0 -2,-0.3 -0.533 56.1 154.9 -64.2 117.5 -14.3 19.2 15.8 110 257 A S - 0 0 38 -2,-0.5 2,-1.6 -5,-0.1 3,-0.2 -0.925 47.7-136.8-155.1 121.0 -13.6 17.8 12.4 111 258 A A + 0 0 40 -2,-0.3 79,-0.1 1,-0.2 76,-0.1 -0.639 59.1 129.8 -75.1 89.4 -13.8 19.4 8.9 112 259 A H + 0 0 16 -2,-1.6 48,-0.6 2,-0.1 2,-0.3 0.335 27.0 119.6-127.3 1.1 -15.5 16.4 7.3 113 260 A K E -F 159 0C 86 -3,-0.2 75,-3.0 46,-0.2 76,-0.4 -0.561 52.3-144.7 -78.1 130.0 -18.3 18.0 5.5 114 261 A L E -FG 158 187C 2 44,-2.8 44,-2.6 -2,-0.3 2,-0.6 -0.753 1.8-146.4 -96.1 140.8 -18.4 17.6 1.7 115 262 A F E -FG 157 186C 55 71,-3.3 71,-1.5 -2,-0.4 2,-0.7 -0.942 14.6-164.7-103.5 115.1 -19.6 20.2 -0.7 116 263 A I E +FG 156 185C 4 40,-2.7 40,-1.9 -2,-0.6 2,-0.2 -0.901 19.6 162.2-105.4 110.0 -21.2 18.5 -3.7 117 264 A G E +FG 155 184C 5 67,-3.1 67,-2.8 -2,-0.7 38,-0.2 -0.746 40.3 65.1-122.1 171.7 -21.6 20.9 -6.7 118 265 A G + 0 0 21 36,-0.5 60,-0.5 1,-0.3 63,-0.2 0.776 69.2 140.4 86.0 28.8 -22.2 20.5 -10.4 119 266 A L - 0 0 15 35,-2.3 -1,-0.3 -3,-0.2 2,-0.1 -0.836 51.8-119.5-106.4 142.1 -25.7 19.1 -10.0 120 267 A P > - 0 0 12 0, 0.0 3,-0.7 0, 0.0 34,-0.2 -0.361 20.4-124.8 -70.4 160.4 -28.8 19.9 -12.1 121 268 A N T 3 S+ 0 0 86 1,-0.2 31,-0.7 32,-0.1 33,-0.1 0.579 102.1 72.2 -88.4 -9.5 -31.8 21.3 -10.4 122 269 A Y T 3 S+ 0 0 171 29,-0.1 2,-0.6 2,-0.1 -1,-0.2 0.503 72.9 106.3 -83.1 -2.1 -34.3 18.7 -11.6 123 270 A L < - 0 0 30 -3,-0.7 29,-0.2 4,-0.0 31,-0.1 -0.684 67.2-142.8 -78.7 117.4 -32.6 16.3 -9.2 124 271 A N > - 0 0 72 -2,-0.6 4,-2.0 1,-0.1 3,-0.5 -0.415 22.5-105.1 -82.4 160.1 -35.0 15.7 -6.3 125 272 A D H > S+ 0 0 57 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.835 116.9 55.1 -52.2 -44.5 -34.0 15.3 -2.7 126 273 A D H > S+ 0 0 96 1,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.913 108.6 47.3 -59.8 -45.3 -34.6 11.6 -2.6 127 274 A Q H > S+ 0 0 100 -3,-0.5 4,-2.7 2,-0.2 -1,-0.2 0.927 112.3 49.3 -62.5 -46.5 -32.3 10.9 -5.6 128 275 A V H X S+ 0 0 9 -4,-2.0 4,-2.1 1,-0.2 5,-0.2 0.920 114.1 45.5 -61.5 -44.6 -29.5 13.0 -4.2 129 276 A K H X S+ 0 0 80 -4,-2.5 4,-2.8 -5,-0.2 5,-0.2 0.944 112.4 50.8 -62.9 -48.1 -29.6 11.4 -0.8 130 277 A E H X S+ 0 0 67 -4,-2.7 4,-1.3 -5,-0.2 -2,-0.2 0.923 110.1 50.4 -56.5 -47.8 -29.8 7.9 -2.3 131 278 A L H >< S+ 0 0 77 -4,-2.7 3,-0.7 1,-0.2 -1,-0.2 0.951 116.1 39.5 -55.7 -54.7 -26.8 8.5 -4.5 132 279 A L H >< S+ 0 0 5 -4,-2.1 3,-1.3 1,-0.2 -1,-0.2 0.829 112.5 56.3 -69.5 -32.1 -24.6 9.8 -1.7 133 280 A T H >< S+ 0 0 48 -4,-2.8 3,-1.1 1,-0.3 -1,-0.2 0.721 95.5 67.5 -72.2 -19.7 -25.8 7.3 0.8 134 281 A S T << S+ 0 0 6 -4,-1.3 -92,-0.6 -3,-0.7 -1,-0.3 0.477 100.4 49.7 -79.6 -0.8 -24.8 4.5 -1.6 135 282 A F B < S-D 41 0A 42 -3,-1.3 -1,-0.2 1,-0.5 -94,-0.2 0.185 128.8 -37.1-120.7 14.5 -21.1 5.4 -1.0 136 283 A G S < S- 0 0 0 -96,-1.4 -1,-0.5 -3,-1.1 2,-0.4 -0.651 78.8 -58.2 143.7 159.9 -21.2 5.5 2.8 137 284 A P - 0 0 29 0, 0.0 24,-3.2 0, 0.0 2,-0.4 -0.522 48.6-145.5 -71.4 122.4 -23.3 6.4 5.9 138 285 A L E -H 160 0C 39 -2,-0.4 22,-0.3 22,-0.3 3,-0.1 -0.726 19.9-178.5 -89.0 135.5 -24.3 10.1 5.9 139 286 A K E S+ 0 0 119 20,-3.2 2,-0.3 -2,-0.4 21,-0.2 0.679 76.6 22.7 -99.3 -26.8 -24.6 11.8 9.3 140 287 A A E +H 159 0C 38 19,-1.7 19,-1.9 2,-0.0 -1,-0.3 -0.998 59.9 175.8-145.2 136.7 -25.7 15.1 7.8 141 288 A F E +H 158 0C 53 -2,-0.3 2,-0.5 17,-0.2 17,-0.2 -0.903 5.7 167.1-144.8 110.1 -27.4 16.1 4.6 142 289 A N E -H 157 0C 69 15,-2.7 15,-2.6 -2,-0.3 2,-0.5 -0.970 18.3-156.6-127.6 117.0 -28.5 19.6 3.7 143 290 A L E -H 156 0C 26 -2,-0.5 2,-0.7 13,-0.2 13,-0.2 -0.789 18.6-128.5 -93.2 130.0 -29.6 20.4 0.1 144 291 A V E +H 155 0C 38 11,-1.7 9,-3.3 -2,-0.5 11,-0.5 -0.686 35.6 176.8 -82.6 112.1 -29.3 24.1 -0.9 145 292 A K E -H 152 0C 84 -2,-0.7 2,-0.5 7,-0.3 7,-0.3 -0.635 37.0 -97.7-107.0 167.8 -32.6 25.1 -2.4 146 293 A D > - 0 0 52 5,-3.2 4,-1.3 -2,-0.2 -2,-0.0 -0.783 25.7-144.1 -86.5 128.1 -33.9 28.5 -3.7 147 294 A S T 4 S+ 0 0 135 -2,-0.5 -1,-0.1 1,-0.2 -2,-0.0 0.792 97.8 31.1 -63.9 -28.7 -35.9 30.2 -1.1 148 295 A A T 4 S+ 0 0 93 3,-0.1 -1,-0.2 -3,-0.0 -2,-0.0 0.896 127.0 36.7 -95.5 -52.0 -38.3 31.7 -3.7 149 296 A T T 4 S- 0 0 102 2,-0.1 -2,-0.1 1,-0.1 3,-0.1 0.957 88.8-142.1 -68.6 -51.5 -38.4 29.1 -6.5 150 297 A G < + 0 0 41 -4,-1.3 -1,-0.1 1,-0.5 3,-0.1 0.039 61.4 114.4 108.8 -25.1 -38.2 26.0 -4.3 151 298 A L S S- 0 0 89 1,-0.1 -5,-3.2 -6,-0.1 -1,-0.5 -0.258 76.1 -87.3 -73.6 164.4 -35.9 24.1 -6.7 152 299 A S E - H 0 145C 14 -31,-0.7 -7,-0.3 -7,-0.3 -1,-0.1 -0.310 20.8-137.1 -68.2 154.2 -32.4 23.0 -5.8 153 300 A K E - 0 0 90 -9,-3.3 -8,-0.1 2,-0.4 -1,-0.1 0.525 52.9-104.1 -86.9 -8.7 -29.5 25.4 -6.5 154 301 A G E S+ 0 0 3 -10,-0.5 -35,-2.3 1,-0.3 -36,-0.5 0.645 92.1 74.9 96.3 17.2 -27.5 22.4 -7.7 155 302 A Y E -FH 117 144C 72 -11,-0.5 -11,-1.7 -38,-0.2 -2,-0.4 -0.988 50.8-179.9-156.4 155.9 -25.3 21.9 -4.7 156 303 A A E -FH 116 143C 0 -40,-1.9 -40,-2.7 -2,-0.3 2,-0.5 -0.953 26.4-120.4-151.5 166.4 -25.4 20.6 -1.2 157 304 A F E +FH 115 142C 63 -15,-2.6 -15,-2.7 -2,-0.3 2,-0.4 -0.972 35.1 168.2-115.7 127.5 -23.4 19.9 2.0 158 305 A C E -FH 114 141C 0 -44,-2.6 -44,-2.8 -2,-0.5 2,-0.5 -0.991 17.8-159.5-144.2 131.2 -23.2 16.4 3.2 159 306 A E E -FH 113 140C 28 -19,-1.9 -20,-3.2 -2,-0.4 -19,-1.7 -0.943 12.7-143.4-116.1 130.2 -21.0 14.8 5.9 160 307 A Y E - H 0 138C 2 -48,-0.6 -22,-0.3 -2,-0.5 -27,-0.0 -0.478 9.7-138.1 -83.3 158.4 -20.2 11.1 6.1 161 308 A V S S+ 0 0 81 -24,-3.2 -1,-0.1 -2,-0.2 -23,-0.1 0.948 85.7 63.4 -78.6 -55.9 -19.9 9.1 9.3 162 309 A D S S- 0 0 38 -25,-0.4 4,-0.5 1,-0.1 -2,-0.1 -0.396 72.2-145.9 -73.3 147.9 -16.9 7.0 8.4 163 310 A I S S+ 0 0 43 2,-0.1 4,-0.4 1,-0.1 -1,-0.1 0.477 92.5 54.1 -94.0 -4.0 -13.6 8.7 7.6 164 311 A N S >> S+ 0 0 48 2,-0.1 4,-1.2 3,-0.1 3,-0.5 0.898 104.3 48.1 -93.9 -50.7 -12.5 6.2 5.0 165 312 A V H 3> S+ 0 0 6 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.740 99.0 72.8 -64.7 -24.1 -15.4 6.2 2.5 166 313 A T H 3> S+ 0 0 0 -4,-0.5 4,-1.4 1,-0.2 -1,-0.2 0.939 103.8 35.4 -59.5 -50.7 -15.5 10.0 2.5 167 314 A D H <> S+ 0 0 75 -3,-0.5 4,-2.3 -4,-0.4 -1,-0.2 0.816 116.0 56.5 -75.1 -29.0 -12.3 10.5 0.4 168 315 A Q H X S+ 0 0 100 -4,-1.2 4,-1.4 2,-0.2 -2,-0.2 0.888 105.3 51.0 -68.6 -39.3 -13.1 7.3 -1.6 169 316 A A H X>S+ 0 0 4 -4,-2.8 4,-3.1 2,-0.2 5,-0.5 0.877 109.6 51.8 -62.7 -38.3 -16.5 8.8 -2.6 170 317 A I H X5S+ 0 0 29 -4,-1.4 4,-1.2 1,-0.2 -2,-0.2 0.930 105.6 54.4 -61.9 -46.1 -14.6 11.9 -3.7 171 318 A A H <5S+ 0 0 85 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.802 120.5 32.1 -59.9 -30.5 -12.2 9.8 -5.8 172 319 A G H <5S+ 0 0 40 -4,-1.4 -2,-0.2 -5,-0.1 -1,-0.2 0.920 125.3 36.4 -91.9 -54.7 -15.2 8.3 -7.6 173 320 A L H ><5S+ 0 0 3 -4,-3.1 3,-2.5 -5,-0.2 2,-0.5 0.941 98.7 80.2 -69.3 -50.2 -17.9 10.9 -7.7 174 321 A N T 3< S-I 181 0D 54 3,-2.4 3,-2.1 -60,-0.5 2,-0.8 -0.831 70.8 -56.8 -96.7 99.1 -24.3 15.4 -14.8 179 326 A G T 3 S- 0 0 71 -2,-0.9 -60,-0.0 1,-0.3 -2,-0.0 -0.556 123.0 -16.8 68.9-107.5 -25.5 16.6 -18.1 180 327 A D T 3 S+ 0 0 137 -2,-0.8 2,-0.4 2,-0.0 -1,-0.3 0.347 122.7 89.2-110.5 2.4 -23.4 19.7 -18.8 181 328 A K E < S-I 178 0D 82 -3,-2.1 -3,-2.4 -63,-0.2 2,-0.5 -0.848 72.2-134.2-105.1 135.5 -22.2 20.1 -15.3 182 329 A K E -I 177 0D 137 -2,-0.4 2,-0.5 -5,-0.3 -5,-0.3 -0.774 28.5-116.1 -88.5 127.3 -19.1 18.5 -13.9 183 330 A L - 0 0 9 -7,-3.0 -8,-2.0 -2,-0.5 2,-0.6 -0.477 31.4-164.8 -68.5 115.3 -19.6 16.9 -10.5 184 331 A L E +G 117 0C 78 -67,-2.8 -67,-3.1 -2,-0.5 2,-0.5 -0.914 11.5 174.5-106.7 116.0 -17.4 18.7 -8.0 185 332 A V E +G 116 0C 3 -2,-0.6 2,-0.3 -69,-0.2 -69,-0.2 -0.981 18.2 125.5-126.4 120.5 -16.9 16.9 -4.7 186 333 A Q E -G 115 0C 79 -71,-1.5 -71,-3.3 -2,-0.5 2,-0.2 -0.926 61.1 -75.3-154.3 176.8 -14.5 18.2 -2.0 187 334 A R E -G 114 0C 79 -2,-0.3 -73,-0.3 -73,-0.3 -28,-0.0 -0.596 36.9-129.0 -82.3 147.4 -14.5 19.1 1.7 188 335 A A S S+ 0 0 47 -75,-3.0 -74,-0.1 -2,-0.2 -1,-0.1 0.781 99.8 37.7 -68.2 -28.4 -16.1 22.5 2.6 189 336 A S + 0 0 78 -76,-0.4 -1,-0.1 -78,-0.0 -77,-0.0 0.924 68.8 171.1 -86.6 -82.5 -13.1 23.7 4.6 190 337 A V - 0 0 41 -79,-0.1 3,-0.1 2,-0.1 -4,-0.0 0.857 26.8-143.7 63.5 107.1 -9.7 22.6 3.0 191 338 A G - 0 0 85 1,-0.2 2,-0.2 2,-0.0 0, 0.0 0.998 64.9 -43.9 -61.8 -71.7 -6.8 24.3 4.8 192 339 A A + 0 0 82 1,-0.0 -1,-0.2 2,-0.0 -2,-0.1 -0.596 65.7 148.7-169.6 98.9 -4.4 25.0 2.0 193 340 A K - 0 0 138 -2,-0.2 -1,-0.0 2,-0.1 -3,-0.0 0.839 24.0-169.4 -96.0 -49.5 -3.5 22.5 -0.8 194 341 A N 0 0 159 1,-0.2 -2,-0.0 0, 0.0 0, 0.0 0.682 360.0 360.0 64.2 21.0 -2.9 25.0 -3.6 195 342 A A 0 0 139 0, 0.0 -1,-0.2 0, 0.0 -2,-0.1 -0.128 360.0 360.0 -98.9 360.0 -2.8 21.9 -5.9