==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=24-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSCRIPTION 26-APR-11 2YH1 . COMPND 2 MOLECULE: SPLICING FACTOR U2AF 65 KDA SUBUNIT; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.D.MACKERETH,T.MADL,B.SIMON,K.ZANIER,A.GASCH,M.SATTLER . 195 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12605.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 118 60.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 42 21.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 19 9.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 16 8.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 36 18.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 1 0 1 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 2 2 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 148 A A 0 0 38 0, 0.0 2,-0.2 0, 0.0 61,-0.1 0.000 360.0 360.0 360.0 121.5 -69.8 5.0 1.9 2 149 A R + 0 0 140 59,-0.1 53,-1.0 54,-0.1 2,-0.3 -0.316 360.0 74.7 -95.1 46.7 -73.4 6.4 1.7 3 150 A R E -A 54 0A 81 51,-0.2 2,-0.3 -2,-0.2 51,-0.2 -0.987 56.9-165.4-157.1 148.6 -72.4 9.5 3.6 4 151 A L E -A 53 0A 0 49,-1.6 49,-2.7 -2,-0.3 2,-0.5 -0.997 18.7-131.8-140.8 143.6 -70.5 12.7 3.1 5 152 A Y E -AB 52 80A 71 75,-3.1 75,-2.7 -2,-0.3 2,-0.5 -0.829 21.7-174.8 -96.6 125.2 -69.0 15.4 5.3 6 153 A V E +AB 51 79A 0 45,-3.0 45,-1.7 -2,-0.5 3,-0.3 -0.892 10.7 176.3-124.8 101.2 -69.8 19.0 4.4 7 154 A G E +AB 50 78A 0 71,-2.4 71,-2.2 -2,-0.5 43,-0.2 -0.417 55.0 46.6 -96.8-178.2 -68.1 21.6 6.4 8 155 A N S S+ 0 0 50 41,-1.0 -1,-0.2 69,-0.2 42,-0.2 0.866 78.4 173.2 49.9 40.8 -68.0 25.5 6.4 9 156 A I - 0 0 3 40,-1.2 -1,-0.2 -3,-0.3 3,-0.1 -0.460 40.5 -87.3 -73.8 149.8 -71.9 25.4 5.9 10 157 A P > - 0 0 11 0, 0.0 3,-1.3 0, 0.0 -1,-0.1 -0.231 51.5-100.0 -57.0 144.4 -73.9 28.7 6.0 11 158 A F T 3 S+ 0 0 181 1,-0.2 3,-0.1 -3,-0.1 35,-0.0 -0.425 103.1 10.3 -69.9 139.7 -74.9 29.8 9.5 12 159 A G T 3 S+ 0 0 43 1,-0.2 -1,-0.2 -2,-0.1 2,-0.1 0.543 88.0 157.4 71.2 6.6 -78.5 29.1 10.5 13 160 A I < - 0 0 28 -3,-1.3 -1,-0.2 1,-0.1 2,-0.2 -0.416 38.5-127.6 -66.1 136.5 -79.0 26.9 7.5 14 161 A T > - 0 0 79 -2,-0.1 4,-1.4 -3,-0.1 5,-0.2 -0.516 12.0-122.6 -84.8 153.9 -81.8 24.4 7.9 15 162 A E H > S+ 0 0 96 1,-0.2 4,-1.6 2,-0.2 3,-0.4 0.918 114.8 50.9 -60.1 -43.2 -81.4 20.7 7.3 16 163 A E H > S+ 0 0 140 1,-0.2 4,-3.0 2,-0.2 5,-0.2 0.888 107.2 52.3 -61.7 -45.9 -84.1 20.7 4.7 17 164 A A H > S+ 0 0 35 1,-0.2 4,-0.8 2,-0.2 -1,-0.2 0.772 109.8 52.1 -62.5 -26.6 -82.5 23.8 2.8 18 165 A M H X S+ 0 0 0 -4,-1.4 4,-1.6 -3,-0.4 -1,-0.2 0.800 113.6 43.9 -72.3 -34.1 -79.2 21.7 2.7 19 166 A M H X S+ 0 0 46 -4,-1.6 4,-2.9 2,-0.2 5,-0.3 0.957 110.9 50.7 -74.6 -54.3 -81.2 18.7 1.2 20 167 A D H X S+ 0 0 84 -4,-3.0 4,-1.5 1,-0.2 -1,-0.2 0.817 111.3 52.0 -54.5 -33.7 -83.2 20.6 -1.3 21 168 A F H X S+ 0 0 38 -4,-0.8 4,-1.5 -5,-0.2 -1,-0.2 0.969 112.9 40.7 -69.8 -53.6 -79.9 22.2 -2.6 22 169 A F H X S+ 0 0 0 -4,-1.6 4,-2.7 1,-0.2 3,-0.4 0.933 115.2 50.2 -61.3 -48.3 -77.9 19.0 -3.1 23 170 A N H X S+ 0 0 6 -4,-2.9 4,-1.5 1,-0.2 -1,-0.2 0.874 112.6 48.3 -56.7 -43.0 -80.8 17.1 -4.6 24 171 A A H X S+ 0 0 50 -4,-1.5 4,-1.6 -5,-0.3 -1,-0.2 0.768 112.7 50.5 -67.7 -23.6 -81.4 20.1 -7.0 25 172 A Q H X S+ 0 0 46 -4,-1.5 4,-1.8 -3,-0.4 -2,-0.2 0.851 109.0 50.1 -79.5 -37.6 -77.6 20.0 -7.8 26 173 A M H X>S+ 0 0 0 -4,-2.7 5,-2.5 2,-0.2 4,-0.6 0.857 114.6 44.4 -66.8 -36.8 -77.6 16.3 -8.5 27 174 A R H <5S+ 0 0 135 -4,-1.5 3,-0.2 -5,-0.2 -2,-0.2 0.899 111.7 50.3 -75.9 -43.1 -80.5 16.7 -10.9 28 175 A L H <5S+ 0 0 146 -4,-1.6 -2,-0.2 1,-0.2 -1,-0.2 0.878 116.0 43.7 -63.0 -37.7 -79.3 19.8 -12.7 29 176 A G H <5S- 0 0 45 -4,-1.8 -1,-0.2 -5,-0.1 -2,-0.2 0.660 107.3-128.6 -81.1 -16.4 -75.9 18.1 -13.3 30 177 A G T <5 + 0 0 54 -4,-0.6 -3,-0.2 -3,-0.2 -4,-0.1 0.873 62.3 140.0 70.2 37.0 -77.6 14.8 -14.2 31 178 A L < + 0 0 42 -5,-2.5 2,-0.2 -6,-0.2 -4,-0.2 0.331 33.2 111.4 -92.9 5.3 -75.5 12.9 -11.7 32 179 A T - 0 0 48 -6,-0.6 5,-0.1 1,-0.1 4,-0.0 -0.580 52.9-159.8 -82.6 143.4 -78.4 10.6 -10.6 33 180 A Q S S+ 0 0 110 -2,-0.2 -1,-0.1 1,-0.2 -2,-0.0 0.647 75.5 14.2 -94.6 -18.5 -78.2 6.9 -11.5 34 181 A A S S- 0 0 42 2,-0.2 -1,-0.2 0, 0.0 0, 0.0 -0.967 95.6 -73.3-150.7 163.4 -82.0 6.3 -11.1 35 182 A P S S+ 0 0 123 0, 0.0 2,-0.1 0, 0.0 -2,-0.1 -0.279 91.9 46.6 -59.3 143.5 -85.3 8.2 -10.8 36 183 A G S S- 0 0 29 -4,-0.0 -2,-0.2 0, 0.0 0, 0.0 -0.238 98.0 -52.7 108.4 161.6 -85.8 9.9 -7.4 37 184 A N - 0 0 77 1,-0.1 -14,-0.1 -2,-0.1 -13,-0.1 -0.536 37.0-155.7 -75.3 134.4 -83.7 12.1 -5.1 38 185 A P S S+ 0 0 0 0, 0.0 18,-1.1 0, 0.0 2,-0.7 0.947 79.4 73.6 -73.2 -51.0 -80.3 10.7 -4.1 39 186 A V E +C 55 0A 1 16,-0.2 16,-0.3 1,-0.2 3,-0.1 -0.537 56.4 175.0 -69.6 106.3 -79.9 12.6 -0.8 40 187 A L E - 0 0 119 14,-2.4 2,-0.3 -2,-0.7 -1,-0.2 0.847 66.3 -5.7 -80.9 -37.1 -82.4 10.8 1.7 41 188 A A E -C 54 0A 35 13,-1.2 13,-2.7 -22,-0.0 2,-0.3 -0.929 55.5-155.9-151.4 164.4 -81.4 12.9 4.9 42 189 A V E -C 53 0A 10 -2,-0.3 2,-0.5 11,-0.2 11,-0.2 -0.951 8.3-157.9-146.4 130.5 -78.9 15.6 6.1 43 190 A Q E -C 52 0A 96 9,-2.0 9,-2.2 -2,-0.3 2,-0.5 -0.954 9.6-157.6-114.1 126.6 -77.8 16.2 9.7 44 191 A I E -C 51 0A 31 -2,-0.5 2,-1.1 7,-0.2 7,-0.3 -0.905 14.5-162.6-114.9 126.0 -76.4 19.6 10.8 45 192 A N E >> -C 50 0A 69 5,-3.0 5,-1.8 -2,-0.5 4,-0.8 -0.805 15.8-170.7 -98.1 91.4 -74.2 20.3 13.7 46 193 A Q T >45S+ 0 0 106 -2,-1.1 3,-1.1 1,-0.2 -1,-0.2 0.923 79.8 44.7 -50.3 -57.4 -74.7 24.1 13.9 47 194 A D T 345S+ 0 0 137 1,-0.3 -1,-0.2 -3,-0.1 -2,-0.1 0.928 114.8 48.0 -56.2 -48.8 -72.0 24.9 16.5 48 195 A K T 345S- 0 0 126 2,-0.1 -1,-0.3 1,-0.1 -2,-0.2 0.591 108.1-131.7 -69.0 -9.1 -69.4 22.7 14.8 49 196 A N T <<5 + 0 0 53 -3,-1.1 -40,-1.2 -4,-0.8 -41,-1.0 0.831 66.9 102.9 62.1 36.2 -70.4 24.3 11.5 50 197 A F E < -AC 7 45A 46 -5,-1.8 -5,-3.0 -43,-0.2 2,-0.3 -0.942 47.5-162.8-143.6 168.7 -70.7 21.1 9.6 51 198 A A E -AC 6 44A 0 -45,-1.7 -45,-3.0 -2,-0.3 2,-0.4 -0.959 15.0-133.5-147.6 161.0 -73.3 18.6 8.3 52 199 A F E -AC 5 43A 46 -9,-2.2 -9,-2.0 -2,-0.3 2,-0.4 -0.979 16.5-145.6-123.3 129.5 -73.4 15.0 7.0 53 200 A L E -AC 4 42A 1 -49,-2.7 -49,-1.6 -2,-0.4 2,-0.6 -0.761 7.1-153.4 -94.9 137.6 -75.2 14.0 3.8 54 201 A E E -AC 3 41A 69 -13,-2.7 -14,-2.4 -2,-0.4 -13,-1.2 -0.942 14.5-169.6-114.8 114.7 -77.0 10.7 3.6 55 202 A F E - C 0 39A 5 -53,-1.0 -16,-0.2 -2,-0.6 -53,-0.1 -0.560 27.3-135.3 -99.6 164.7 -77.3 9.1 0.1 56 203 A R S S+ 0 0 79 -18,-1.1 2,-0.3 -2,-0.2 -17,-0.1 0.724 88.7 36.1 -88.6 -26.0 -79.4 6.1 -1.1 57 204 A S S > S- 0 0 13 -19,-0.1 4,-1.3 1,-0.1 -2,-0.1 -0.890 70.9-131.5-128.9 159.6 -76.5 4.7 -3.2 58 205 A V H > S+ 0 0 58 -2,-0.3 4,-1.9 2,-0.2 5,-0.1 0.885 106.8 50.8 -74.3 -41.7 -72.8 4.4 -3.0 59 206 A D H > S+ 0 0 79 1,-0.2 4,-1.4 2,-0.2 -1,-0.2 0.893 108.0 52.3 -64.7 -41.8 -72.1 5.6 -6.5 60 207 A E H > S+ 0 0 0 2,-0.2 4,-2.1 1,-0.2 3,-0.4 0.920 107.4 51.6 -61.8 -43.8 -74.2 8.8 -6.1 61 208 A T H X S+ 0 0 0 -4,-1.3 4,-0.7 1,-0.2 3,-0.3 0.946 109.8 49.5 -54.2 -54.0 -72.4 9.7 -2.9 62 209 A T H < S+ 0 0 68 -4,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.747 111.6 53.2 -55.2 -27.1 -69.0 9.3 -4.8 63 210 A Q H >< S+ 0 0 76 -4,-1.4 3,-1.4 -3,-0.4 -1,-0.2 0.825 99.8 58.4 -79.2 -34.0 -70.7 11.6 -7.6 64 211 A A H >< S+ 0 0 0 -4,-2.1 3,-2.1 -3,-0.3 -1,-0.2 0.684 85.9 80.0 -68.5 -17.4 -71.6 14.4 -5.2 65 212 A M G >< S+ 0 0 53 -4,-0.7 3,-1.4 1,-0.3 -1,-0.3 0.719 76.1 74.2 -62.1 -19.9 -68.0 14.8 -4.3 66 213 A A G < S+ 0 0 84 -3,-1.4 -1,-0.3 1,-0.3 -2,-0.2 0.591 83.1 69.2 -69.4 -9.4 -67.6 16.8 -7.5 67 214 A F G X + 0 0 32 -3,-2.1 3,-2.0 -4,-0.1 2,-0.3 0.191 68.1 138.6 -93.8 16.2 -69.4 19.6 -5.7 68 215 A D T < S+ 0 0 56 -3,-1.4 10,-0.2 1,-0.3 -3,-0.0 -0.472 74.4 13.7 -65.8 120.9 -66.4 20.2 -3.4 69 216 A G T 3 S+ 0 0 16 8,-2.2 72,-0.4 -2,-0.3 -1,-0.3 0.362 87.9 156.6 95.9 -4.9 -65.9 24.0 -3.0 70 217 A I < - 0 0 36 -3,-2.0 7,-2.1 6,-0.2 2,-0.6 -0.209 47.3-113.0 -55.1 142.4 -69.3 24.9 -4.5 71 218 A I E +D 76 0B 111 5,-0.2 2,-0.4 3,-0.1 5,-0.2 -0.700 40.9 171.0 -84.9 121.5 -70.6 28.3 -3.5 72 219 A F E > S-D 75 0B 12 3,-2.4 3,-1.4 -2,-0.6 -3,-0.0 -0.917 70.6 -23.0-135.3 107.7 -73.7 28.1 -1.3 73 220 A Q T 3 S- 0 0 139 -2,-0.4 3,-0.1 1,-0.3 -1,-0.1 0.894 125.5 -51.6 60.7 42.7 -75.0 31.3 0.4 74 221 A G T 3 S+ 0 0 44 1,-0.2 2,-0.5 -64,-0.1 -1,-0.3 0.375 118.5 109.6 78.1 -5.5 -71.6 33.0 0.3 75 222 A Q E < -D 72 0B 47 -3,-1.4 -3,-2.4 67,-0.0 2,-1.1 -0.903 67.3-134.9-110.6 130.9 -69.9 30.0 1.9 76 223 A S E -D 71 0B 23 -2,-0.5 -5,-0.2 -5,-0.2 -6,-0.2 -0.696 30.5-135.9 -82.8 101.5 -67.5 27.7 -0.0 77 224 A L - 0 0 1 -7,-2.1 -8,-2.2 -2,-1.1 2,-0.7 -0.291 7.7-145.3 -61.4 137.8 -68.6 24.2 1.0 78 225 A K E -B 7 0A 88 -71,-2.2 -71,-2.4 -10,-0.2 2,-0.5 -0.919 16.4-166.3-108.5 110.2 -66.0 21.7 1.9 79 226 A I E +B 6 0A 1 -2,-0.7 2,-0.3 -73,-0.2 -73,-0.2 -0.864 18.5 152.5-103.9 126.9 -66.9 18.1 0.9 80 227 A R E -B 5 0A 87 -75,-2.7 -75,-3.1 -2,-0.5 -2,-0.0 -0.887 43.8 -95.7-141.6 170.5 -65.0 15.1 2.2 81 228 A R - 0 0 85 -2,-0.3 -77,-0.2 -77,-0.2 -19,-0.0 -0.580 50.1 -93.4 -89.1 154.7 -65.6 11.5 3.0 82 229 A P - 0 0 10 0, 0.0 3,-0.2 0, 0.0 -1,-0.2 0.059 23.9-126.4 -57.4 175.0 -66.5 10.3 6.6 83 230 A H S S+ 0 0 141 1,-0.1 -2,-0.0 0, 0.0 0, 0.0 -0.000 76.8 112.9-116.8 25.8 -63.8 9.1 9.0 84 231 A D + 0 0 132 1,-0.1 2,-1.2 2,-0.1 -1,-0.1 0.618 56.1 96.3 -68.8 -13.2 -65.4 5.7 9.8 85 232 A Y + 0 0 134 -3,-0.2 -1,-0.1 2,-0.0 0, 0.0 -0.714 63.5 179.1 -77.5 98.5 -62.3 4.5 8.1 86 233 A Q - 0 0 116 -2,-1.2 -2,-0.1 1,-0.1 0, 0.0 -0.615 45.3-109.5-100.8 162.1 -60.1 3.8 11.1 87 234 A P - 0 0 103 0, 0.0 3,-0.2 0, 0.0 -1,-0.1 0.800 50.3-143.4 -56.8 -29.4 -56.5 2.5 11.3 88 235 A L - 0 0 131 1,-0.2 2,-2.2 2,-0.1 3,-0.3 0.987 6.3-147.2 62.0 82.8 -58.2 -0.7 12.7 89 236 A P + 0 0 114 0, 0.0 -1,-0.2 0, 0.0 3,-0.1 -0.401 52.2 134.3 -78.5 63.6 -55.7 -2.0 15.3 90 237 A G - 0 0 57 -2,-2.2 -2,-0.1 -3,-0.2 0, 0.0 0.491 54.9-144.0 -90.4 -4.6 -56.5 -5.6 14.8 91 238 A M + 0 0 145 -3,-0.3 3,-0.2 1,-0.1 -1,-0.2 -0.029 69.4 93.3 67.2-174.8 -52.9 -6.6 14.7 92 239 A S S S- 0 0 108 1,-0.2 2,-0.4 2,-0.1 4,-0.1 0.975 76.1-136.6 53.6 60.8 -51.3 -9.2 12.5 93 240 A E + 0 0 103 1,-0.2 -1,-0.2 2,-0.1 5,-0.0 -0.297 66.7 108.3 -56.2 105.6 -50.4 -6.7 9.9 94 241 A N S S+ 0 0 127 -2,-0.4 -1,-0.2 -3,-0.2 -2,-0.1 0.380 78.5 39.0-141.7 -56.3 -51.3 -8.3 6.6 95 242 A P S S+ 0 0 112 0, 0.0 -2,-0.1 0, 0.0 -3,-0.0 0.311 136.1 21.9 -82.4 9.9 -54.5 -6.6 5.0 96 243 A S + 0 0 38 -4,-0.1 2,-2.0 5,-0.0 6,-0.2 0.336 68.0 129.6-131.8 -88.3 -53.0 -3.3 6.3 97 244 A V S S- 0 0 79 1,-0.2 -4,-0.1 2,-0.1 4,-0.1 -0.423 86.6 -83.4 61.7 -81.5 -49.3 -2.9 7.0 98 245 A Y S S+ 0 0 195 -2,-2.0 4,-0.2 2,-0.1 -1,-0.2 -0.071 118.6 36.9-178.1 -61.5 -48.9 0.2 4.9 99 246 A V S > S+ 0 0 72 2,-0.1 3,-2.5 4,-0.0 -2,-0.1 0.955 93.1 88.4 -77.3 -54.3 -48.4 -0.5 1.3 100 247 A P T 3 S+ 0 0 58 0, 0.0 -2,-0.1 0, 0.0 -6,-0.1 -0.248 98.4 22.5 -50.5 117.4 -50.7 -3.6 0.9 101 248 A G T 3 S+ 0 0 85 -4,-0.1 2,-0.2 -2,-0.0 -2,-0.1 -0.053 128.7 45.6 113.3 -30.7 -54.2 -2.2 0.0 102 249 A V < + 0 0 106 -3,-2.5 -6,-0.0 -6,-0.2 0, 0.0 -0.626 56.3 133.8-146.0 78.5 -53.0 1.1 -1.4 103 250 A V - 0 0 107 -2,-0.2 -1,-0.1 3,-0.0 -4,-0.0 0.697 61.9-130.0 -94.3 -24.6 -50.0 0.8 -3.7 104 251 A S - 0 0 66 -5,-0.1 3,-0.2 2,-0.1 -2,-0.1 0.867 7.1-141.8 70.4 104.0 -51.6 3.1 -6.3 105 252 A T S S- 0 0 151 1,-0.2 2,-0.2 0, 0.0 -1,-0.0 0.931 81.5 -34.9 -56.1 -48.3 -51.6 1.8 -9.8 106 253 A V - 0 0 113 2,-0.0 -1,-0.2 0, 0.0 -2,-0.1 -0.593 60.4-129.1-178.8 113.0 -50.8 5.3 -11.0 107 254 A V - 0 0 111 -3,-0.2 3,-0.1 -2,-0.2 2,-0.0 -0.527 30.1-130.7 -68.5 127.1 -51.9 8.7 -9.6 108 255 A P - 0 0 99 0, 0.0 2,-1.1 0, 0.0 -1,-0.1 -0.284 38.9 -78.8 -70.8 163.1 -53.4 10.9 -12.4 109 256 A D S S+ 0 0 142 -2,-0.0 2,-0.3 3,-0.0 3,-0.1 -0.527 87.9 118.4 -66.9 99.0 -52.4 14.5 -12.9 110 257 A S + 0 0 78 -2,-1.1 -3,-0.0 1,-0.2 0, 0.0 -0.872 25.0 67.4-150.7 179.3 -54.4 16.1 -10.1 111 258 A A + 0 0 77 -2,-0.3 -1,-0.2 1,-0.1 78,-0.1 0.986 38.4 151.9 62.0 85.5 -54.0 18.0 -6.8 112 259 A H + 0 0 37 48,-0.1 48,-0.3 -3,-0.1 -1,-0.1 -0.050 19.5 154.3-128.8 31.0 -52.7 21.5 -7.5 113 260 A K - 0 0 69 46,-0.1 75,-2.0 74,-0.1 76,-0.5 -0.341 32.4-142.6 -62.9 139.4 -54.3 23.3 -4.6 114 261 A L E -EF 158 187C 1 44,-3.3 44,-1.9 73,-0.3 2,-0.5 -0.842 1.9-143.0-109.9 143.9 -52.4 26.4 -3.5 115 262 A F E -EF 157 186C 56 71,-3.0 71,-1.5 -2,-0.4 2,-0.5 -0.879 16.1-169.7-104.4 132.1 -51.8 27.7 -0.0 116 263 A I E +EF 156 185C 0 40,-2.2 40,-2.5 -2,-0.5 2,-0.2 -0.977 13.5 164.0-127.0 121.3 -51.9 31.5 0.5 117 264 A G E + F 0 184C 6 67,-2.6 67,-1.8 -2,-0.5 38,-0.2 -0.704 46.6 58.9-127.2 179.2 -50.9 33.1 3.8 118 265 A G + 0 0 24 36,-0.4 60,-0.2 1,-0.3 37,-0.2 0.584 69.3 156.5 76.8 9.2 -49.9 36.5 5.2 119 266 A L - 0 0 4 35,-2.0 -1,-0.3 -3,-0.2 63,-0.1 -0.477 49.6-107.3 -70.9 135.2 -53.3 37.8 4.1 120 267 A P > - 0 0 9 0, 0.0 3,-1.0 0, 0.0 34,-0.2 -0.344 23.3-126.2 -61.8 141.6 -54.5 40.8 6.1 121 268 A N T 3 S+ 0 0 101 1,-0.2 31,-0.8 32,-0.1 33,-0.1 0.640 104.0 63.2 -65.4 -14.9 -57.4 39.9 8.5 122 269 A Y T 3 S+ 0 0 155 29,-0.1 -1,-0.2 2,-0.0 -3,-0.0 0.749 79.7 96.5 -84.2 -23.1 -59.6 42.6 7.0 123 270 A L < - 0 0 27 -3,-1.0 29,-0.3 1,-0.1 2,-0.2 -0.325 60.5-154.4 -66.4 149.1 -59.9 41.2 3.5 124 271 A N > - 0 0 60 27,-0.1 4,-2.8 28,-0.0 3,-0.4 -0.520 34.6 -84.4-114.5-176.5 -63.0 39.0 2.7 125 272 A D H > S+ 0 0 30 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.903 127.0 46.7 -53.5 -55.4 -63.7 36.2 0.2 126 273 A D H > S+ 0 0 114 2,-0.2 4,-0.6 1,-0.2 -1,-0.2 0.731 117.3 47.0 -61.7 -26.1 -64.6 38.5 -2.9 127 274 A Q H > S+ 0 0 97 -3,-0.4 4,-1.7 2,-0.2 -2,-0.2 0.903 115.8 41.8 -80.3 -48.3 -61.4 40.6 -2.1 128 275 A V H X S+ 0 0 3 -4,-2.8 4,-1.5 1,-0.2 -2,-0.2 0.942 112.6 54.2 -62.6 -49.2 -59.0 37.7 -1.7 129 276 A K H X S+ 0 0 60 -4,-2.7 4,-3.0 -5,-0.3 -1,-0.2 0.841 105.4 55.8 -54.4 -36.4 -60.5 35.9 -4.7 130 277 A E H X S+ 0 0 139 -4,-0.6 4,-1.5 2,-0.2 -1,-0.2 0.960 102.7 52.5 -62.0 -53.4 -59.9 38.9 -6.8 131 278 A L H < S+ 0 0 36 -4,-1.7 -1,-0.2 1,-0.2 -2,-0.2 0.824 117.3 41.6 -51.7 -33.2 -56.2 39.1 -6.1 132 279 A L H >< S+ 0 0 2 -4,-1.5 3,-1.7 1,-0.2 4,-0.3 0.871 105.3 61.2 -82.6 -41.5 -56.0 35.4 -7.2 133 280 A T H >< S+ 0 0 69 -4,-3.0 3,-1.8 1,-0.3 -2,-0.2 0.738 80.7 85.0 -56.9 -29.6 -58.3 35.7 -10.2 134 281 A S T 3< S+ 0 0 96 -4,-1.5 -1,-0.3 1,-0.3 -2,-0.1 0.601 95.9 44.9 -50.6 -10.0 -55.8 38.2 -11.8 135 282 A F T < S- 0 0 69 -3,-1.7 -1,-0.3 1,-0.4 -2,-0.2 0.535 130.8 -57.2-111.8 -12.0 -54.0 35.0 -13.1 136 283 A G S < S- 0 0 16 -3,-1.8 -1,-0.4 -4,-0.3 0, 0.0 -0.727 71.3 -49.9 149.1 162.3 -57.0 33.1 -14.3 137 284 A P - 0 0 95 0, 0.0 24,-1.8 0, 0.0 25,-0.4 -0.221 53.2-129.9 -59.7 147.0 -60.4 31.6 -13.2 138 285 A L E -G 160 0C 41 22,-0.3 22,-0.3 1,-0.1 3,-0.1 -0.769 17.0-167.0-102.4 146.3 -60.5 29.5 -10.1 139 286 A K E S+ 0 0 110 20,-3.5 2,-0.3 1,-0.3 21,-0.2 0.594 81.7 12.6-101.0 -22.7 -62.1 26.0 -9.8 140 287 A A E +G 159 0C 28 19,-1.5 19,-2.1 -70,-0.0 2,-0.3 -0.871 65.4 169.4-158.9 125.6 -62.1 25.9 -5.8 141 288 A F E +G 158 0C 17 -72,-0.4 2,-0.3 -2,-0.3 17,-0.2 -0.995 2.6 173.9-142.8 134.8 -61.4 28.6 -3.2 142 289 A N E -G 157 0C 40 15,-2.8 15,-2.8 -2,-0.3 2,-0.6 -0.963 15.8-156.7-144.8 124.1 -61.9 28.7 0.6 143 290 A L E -G 156 0C 4 -2,-0.3 2,-0.4 13,-0.2 13,-0.2 -0.884 24.8-130.7-101.0 118.1 -60.9 31.4 3.1 144 291 A V E - 0 0 29 11,-1.6 9,-3.1 -2,-0.6 11,-0.4 -0.560 29.0-177.3 -74.2 122.8 -60.4 30.1 6.6 145 292 A K E -G 152 0C 46 -2,-0.4 7,-0.2 7,-0.3 6,-0.1 -0.896 35.1 -92.0-119.1 148.1 -62.3 32.1 9.3 146 293 A D > - 0 0 56 5,-2.3 4,-0.7 -2,-0.3 -1,-0.0 -0.273 33.8-124.0 -58.9 141.1 -62.3 31.6 13.0 147 294 A S T 4 S+ 0 0 126 2,-0.1 -1,-0.1 1,-0.1 -2,-0.0 0.947 103.5 15.0 -49.6 -61.8 -65.1 29.4 14.3 148 295 A A T 4 S+ 0 0 93 1,-0.1 -1,-0.1 2,-0.0 -2,-0.0 0.973 129.5 48.0 -80.2 -64.0 -66.6 31.9 16.8 149 296 A T T 4 S- 0 0 97 1,-0.1 -2,-0.1 2,-0.0 3,-0.1 0.913 86.1-153.5 -42.5 -59.3 -65.0 35.2 15.8 150 297 A G < + 0 0 35 -4,-0.7 -1,-0.1 1,-0.3 2,-0.1 0.348 49.3 120.5 97.6 -6.0 -65.8 34.7 12.1 151 298 A L S S- 0 0 109 1,-0.2 -5,-2.3 -6,-0.1 -1,-0.3 -0.412 75.0 -72.8 -88.3 167.6 -63.0 36.8 10.7 152 299 A S E - G 0 145C 15 -31,-0.8 -7,-0.3 -29,-0.3 -1,-0.2 -0.258 29.4-148.6 -59.1 142.1 -60.2 35.7 8.4 153 300 A K E - 0 0 100 -9,-3.1 -1,-0.1 2,-0.3 -8,-0.1 0.539 51.7-101.0 -88.0 -9.5 -57.5 33.6 10.0 154 301 A G E S+ 0 0 10 -10,-0.4 -35,-2.0 1,-0.2 -36,-0.4 0.365 94.0 77.9 105.5 -3.3 -55.0 35.1 7.6 155 302 A Y E - 0 0 84 -11,-0.4 -11,-1.6 -38,-0.2 -2,-0.3 -0.997 49.5-177.6-143.0 146.4 -54.8 32.2 5.1 156 303 A A E -EG 116 143C 0 -40,-2.5 -40,-2.2 -2,-0.3 2,-0.3 -0.969 17.2-135.9-140.6 155.1 -56.8 30.8 2.2 157 304 A F E +EG 115 142C 43 -15,-2.8 -15,-2.8 -2,-0.3 2,-0.3 -0.850 27.0 166.3-111.3 146.9 -56.7 27.9 -0.2 158 305 A C E -EG 114 141C 2 -44,-1.9 -44,-3.3 -2,-0.3 2,-0.3 -0.994 19.3-162.0-157.9 156.2 -57.4 28.0 -4.0 159 306 A E E - G 0 140C 38 -19,-2.1 -20,-3.5 -2,-0.3 -19,-1.5 -0.975 17.0-139.4-145.3 127.2 -57.1 26.0 -7.2 160 307 A Y E - G 0 138C 1 -2,-0.3 -22,-0.3 -48,-0.3 3,-0.1 -0.355 19.7-123.5 -82.5 164.9 -57.2 27.3 -10.8 161 308 A V S S+ 0 0 86 -24,-1.8 2,-0.9 1,-0.2 -23,-0.1 0.925 106.4 51.8 -71.6 -46.1 -58.9 25.6 -13.7 162 309 A D S >> S- 0 0 80 -25,-0.4 3,-1.2 1,-0.2 4,-0.6 -0.821 75.2-161.4 -96.3 102.4 -55.7 25.5 -15.8 163 310 A I H >> S+ 0 0 48 -2,-0.9 3,-1.4 1,-0.3 4,-0.8 0.799 86.2 65.6 -52.7 -35.0 -53.1 23.9 -13.5 164 311 A N H >> S+ 0 0 103 1,-0.3 4,-1.3 2,-0.2 3,-0.9 0.914 96.2 57.5 -56.9 -38.7 -50.2 25.3 -15.6 165 312 A V H <> S+ 0 0 23 -3,-1.2 4,-2.7 1,-0.3 -1,-0.3 0.778 91.0 74.8 -62.8 -22.6 -51.3 28.8 -14.5 166 313 A T H < S+ 0 0 5 -4,-1.5 3,-2.6 -5,-0.2 -3,-0.2 0.874 90.4 94.6 -96.9 -45.8 -48.0 36.4 -6.0 174 321 A N T 3< S+ 0 0 75 -4,-2.5 10,-0.2 -5,-0.4 3,-0.1 -0.211 97.9 16.0 -50.5 130.1 -45.5 34.8 -3.6 175 322 A G T 3 S+ 0 0 45 8,-2.5 -1,-0.3 1,-0.3 8,-0.1 0.197 89.9 148.6 90.1 -16.7 -43.6 37.5 -1.7 176 323 A M < - 0 0 71 -3,-2.6 7,-3.3 6,-0.2 2,-0.7 -0.110 51.3-115.8 -50.6 147.1 -46.1 40.2 -2.7 177 324 A Q E +H 182 0D 154 5,-0.2 2,-0.6 -3,-0.1 5,-0.2 -0.809 35.2 176.4 -95.1 115.7 -46.6 43.0 -0.2 178 325 A L E > -H 181 0D 28 3,-2.3 3,-2.0 -2,-0.7 2,-0.4 -0.939 62.9 -53.1-120.2 106.7 -50.1 43.2 1.3 179 326 A G T 3 S- 0 0 45 -2,-0.6 -60,-0.0 1,-0.3 -2,-0.0 -0.510 118.5 -25.8 67.1-118.6 -50.4 45.9 4.0 180 327 A D T 3 S+ 0 0 175 -2,-0.4 2,-0.3 -3,-0.0 -1,-0.3 0.053 123.6 86.6-115.9 22.4 -47.7 45.2 6.5 181 328 A K E < S-H 178 0D 101 -3,-2.0 -3,-2.3 -63,-0.1 2,-0.6 -0.892 73.5-125.9-123.8 153.9 -47.4 41.5 5.7 182 329 A K E -H 177 0D 166 -2,-0.3 -5,-0.2 -5,-0.2 -6,-0.2 -0.878 31.9-125.1-101.7 118.3 -45.4 39.5 3.2 183 330 A L - 0 0 0 -7,-3.3 -8,-2.5 -2,-0.6 2,-0.4 -0.292 22.0-160.0 -63.0 143.1 -47.6 37.2 1.1 184 331 A L E +F 117 0C 91 -67,-1.8 -67,-2.6 -10,-0.2 2,-0.4 -0.994 12.2 175.2-128.1 128.1 -46.7 33.5 1.0 185 332 A V E +F 116 0C 4 -2,-0.4 2,-0.3 -69,-0.2 -69,-0.2 -0.982 12.9 144.1-138.0 123.9 -47.9 31.1 -1.8 186 333 A Q E -F 115 0C 83 -71,-1.5 -71,-3.0 -2,-0.4 6,-0.2 -0.983 60.2 -76.5-152.6 155.4 -46.9 27.5 -2.2 187 334 A R E -F 114 0C 73 4,-1.4 -73,-0.3 -2,-0.3 4,-0.1 -0.395 44.0-130.4 -58.7 122.5 -48.5 24.3 -3.3 188 335 A A S S+ 0 0 32 -75,-2.0 -1,-0.2 -30,-0.2 -74,-0.2 0.579 99.6 21.6 -50.9 -11.8 -50.7 23.3 -0.4 189 336 A S S S- 0 0 88 -76,-0.5 2,-0.4 1,-0.2 3,-0.1 0.607 133.1 -15.0-119.4 -77.8 -49.2 19.8 -0.6 190 337 A V S S+ 0 0 120 1,-0.1 -1,-0.2 2,-0.0 -2,-0.1 -0.997 98.1 72.6-135.6 136.5 -45.9 19.5 -2.4 191 338 A G + 0 0 27 -2,-0.4 -4,-1.4 -4,-0.1 -1,-0.1 0.660 35.1 139.5 125.9 53.4 -44.2 22.1 -4.6 192 339 A A + 0 0 65 -6,-0.2 2,-0.3 -3,-0.1 -7,-0.1 0.387 69.8 56.4 -97.8 -0.0 -42.9 25.0 -2.6 193 340 A K S S- 0 0 198 -6,-0.0 2,-0.4 2,-0.0 -6,-0.1 -0.811 70.8-141.9-126.1 167.2 -39.7 25.1 -4.8 194 341 A N 0 0 148 -2,-0.3 -3,-0.0 0, 0.0 -2,-0.0 -0.964 360.0 360.0-137.6 118.7 -39.0 25.4 -8.5 195 342 A A 0 0 141 -2,-0.4 -2,-0.0 0, 0.0 0, 0.0 -0.559 360.0 360.0 -83.4 360.0 -36.2 23.6 -10.3