==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 10-FEB-05 1YT7 . COMPND 2 MOLECULE: CATHEPSIN K; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR D.G.BARRETT,V.M.BONCEK,J.G.CATALANO,D.N.DEATON,A.M.HASSELL, . 214 1 3 3 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 9956.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 134 62.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 3 1.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 40 18.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 15 7.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 20 9.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 45 21.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 1 0 0 1 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 2 1 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A P 0 0 168 0, 0.0 2,-2.8 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 108.9 -6.7 56.2 227.1 2 3 A D + 0 0 61 2,-0.0 2,-0.3 167,-0.0 0, 0.0 -0.258 360.0 71.2 -73.6 57.9 -4.9 53.9 224.6 3 4 A S + 0 0 66 -2,-2.8 2,-0.3 166,-0.1 166,-0.2 -0.963 47.4 175.3-168.9 149.7 -4.1 56.6 222.1 4 5 A V E -A 168 0A 31 164,-2.3 164,-1.7 -2,-0.3 2,-0.4 -0.966 11.0-164.6-159.1 142.0 -1.9 59.7 221.5 5 6 A D E >> -A 167 0A 28 -2,-0.3 3,-1.2 162,-0.2 4,-0.8 -0.840 1.6-171.4-134.7 99.3 -1.3 62.1 218.6 6 7 A Y H 3>>S+ 0 0 9 160,-2.2 5,-2.2 -2,-0.4 4,-0.7 0.689 84.1 70.2 -62.8 -19.3 1.8 64.2 218.9 7 8 A R H >45S+ 0 0 87 159,-0.3 3,-0.7 1,-0.2 -1,-0.3 0.915 102.0 45.8 -63.0 -38.9 0.7 66.3 215.9 8 9 A K H <45S+ 0 0 176 -3,-1.2 -1,-0.2 1,-0.2 -2,-0.2 0.712 109.0 56.2 -74.1 -22.1 -2.0 67.7 218.2 9 10 A K H 3<5S- 0 0 103 -4,-0.8 -1,-0.2 0, 0.0 -2,-0.2 0.534 115.9-115.5 -86.7 -7.2 0.5 68.2 220.9 10 11 A G T <<5S+ 0 0 26 -3,-0.7 -3,-0.2 -4,-0.7 -2,-0.1 0.831 82.7 117.9 78.4 33.2 2.7 70.3 218.7 11 12 A Y < + 0 0 38 -5,-2.2 2,-0.5 155,-0.1 27,-0.2 0.512 57.5 80.0-103.7 -11.1 5.7 68.1 218.5 12 13 A V - 0 0 20 -6,-0.6 3,-0.1 -5,-0.2 -2,-0.1 -0.872 66.6-147.9-109.4 128.4 5.5 67.4 214.8 13 14 A T - 0 0 3 -2,-0.5 3,-0.1 1,-0.2 -2,-0.1 -0.348 44.4 -70.4 -81.7 165.7 6.8 69.8 212.1 14 15 A P - 0 0 78 0, 0.0 2,-0.2 0, 0.0 -1,-0.2 -0.055 63.7 -88.4 -51.7 160.4 5.1 70.0 208.7 15 16 A V - 0 0 16 175,-0.2 170,-0.2 -3,-0.1 2,-0.2 -0.533 46.5-149.9 -74.4 137.3 5.6 67.1 206.3 16 17 A K - 0 0 49 165,-0.5 168,-2.7 -2,-0.2 2,-0.5 -0.569 9.2-137.0-104.7 169.6 8.7 67.2 204.1 17 18 A N B -I 183 0B 105 166,-0.3 166,-0.2 -2,-0.2 168,-0.0 -0.960 13.0-172.6-129.1 109.4 9.5 65.9 200.7 18 19 A Q > - 0 0 15 164,-2.6 3,-0.6 -2,-0.5 5,-0.2 0.597 24.1-154.3 -80.1 -12.3 12.9 64.3 200.4 19 20 A G T 3 - 0 0 46 163,-0.3 -1,-0.2 1,-0.2 4,-0.1 -0.373 54.3 -36.9 71.6-154.2 12.8 63.8 196.6 20 21 A Q T 3 S+ 0 0 190 2,-0.1 -1,-0.2 70,-0.1 -2,-0.1 0.689 103.8 110.8 -80.1 -22.0 14.9 61.0 195.1 21 22 A a S < S- 0 0 11 -3,-0.6 2,-2.9 1,-0.2 3,-0.2 -0.327 79.0-122.1 -55.8 129.8 17.9 61.4 197.5 22 23 A G S S+ 0 0 21 40,-1.4 42,-0.5 1,-0.2 3,-0.3 -0.276 74.2 124.0 -73.5 58.4 18.0 58.4 199.7 23 24 A S >> + 0 0 0 -2,-2.9 4,-1.8 1,-0.2 3,-1.5 0.177 20.1 119.3-104.7 16.0 17.8 60.6 202.8 24 25 A C H 3> S+ 0 0 18 1,-0.3 4,-2.5 2,-0.2 5,-0.2 0.875 77.3 54.8 -49.6 -39.8 14.7 59.0 204.4 25 26 A W H 3> S+ 0 0 1 -3,-0.3 4,-2.3 1,-0.2 -1,-0.3 0.810 105.3 53.8 -64.5 -29.5 16.8 58.1 207.5 26 27 A A H <> S+ 0 0 0 -3,-1.5 4,-2.8 2,-0.2 5,-0.2 0.911 111.0 43.3 -71.1 -44.1 17.8 61.8 207.8 27 28 A F H X S+ 0 0 21 -4,-1.8 4,-2.3 2,-0.2 -2,-0.2 0.886 114.9 50.7 -68.6 -38.5 14.2 63.0 207.8 28 29 A S H X S+ 0 0 4 -4,-2.5 4,-1.9 -5,-0.3 -2,-0.2 0.941 112.0 48.2 -63.0 -46.1 13.3 60.3 210.2 29 30 A S H X S+ 0 0 0 -4,-2.3 4,-1.9 1,-0.2 -2,-0.2 0.944 113.1 45.0 -61.4 -50.7 16.2 61.2 212.4 30 31 A V H X S+ 0 0 5 -4,-2.8 4,-3.4 1,-0.2 5,-0.3 0.890 107.6 62.9 -61.2 -35.5 15.4 64.9 212.5 31 32 A G H X S+ 0 0 4 -4,-2.3 4,-1.4 1,-0.2 -1,-0.2 0.944 105.9 42.0 -52.2 -53.8 11.8 64.0 213.0 32 33 A A H X S+ 0 0 0 -4,-1.9 4,-1.8 1,-0.2 -1,-0.2 0.875 115.4 51.5 -62.0 -38.8 12.6 62.3 216.4 33 34 A L H X S+ 0 0 0 -4,-1.9 4,-2.2 1,-0.2 -2,-0.2 0.905 104.3 55.6 -66.5 -42.2 14.9 65.2 217.3 34 35 A E H X S+ 0 0 6 -4,-3.4 4,-1.7 1,-0.2 -1,-0.2 0.853 108.4 51.5 -59.1 -33.6 12.3 67.8 216.5 35 36 A G H X S+ 0 0 0 -4,-1.4 4,-2.2 -5,-0.3 -1,-0.2 0.918 110.8 43.4 -70.7 -45.5 10.0 66.1 219.0 36 37 A Q H X S+ 0 0 12 -4,-1.8 4,-2.2 2,-0.2 -2,-0.2 0.778 113.0 55.0 -70.2 -26.7 12.4 65.9 221.9 37 38 A L H X S+ 0 0 9 -4,-2.2 4,-2.5 2,-0.2 6,-0.7 0.889 108.9 46.8 -71.1 -41.4 13.4 69.5 221.2 38 39 A K H X S+ 0 0 50 -4,-1.7 4,-1.9 -5,-0.2 -2,-0.2 0.935 113.4 49.5 -63.9 -46.4 9.8 70.6 221.4 39 40 A K H < S+ 0 0 100 -4,-2.2 -2,-0.2 2,-0.2 -1,-0.2 0.896 118.1 38.5 -60.2 -44.2 9.4 68.6 224.6 40 41 A K H < S+ 0 0 141 -4,-2.2 -2,-0.2 1,-0.1 -3,-0.2 0.951 132.4 20.6 -75.1 -52.6 12.5 70.1 226.3 41 42 A T H < S- 0 0 81 -4,-2.5 -3,-0.2 2,-0.2 -2,-0.2 0.465 93.6-125.6 -99.0 -2.7 12.4 73.7 225.2 42 43 A G S < S+ 0 0 45 -4,-1.9 2,-0.4 -5,-0.4 -4,-0.2 0.509 74.1 124.4 70.7 0.6 8.7 74.0 224.3 43 44 A K - 0 0 41 -6,-0.7 2,-0.6 2,-0.0 -1,-0.3 -0.810 50.2-155.6 -99.5 133.9 10.0 75.2 220.9 44 45 A L + 0 0 75 -2,-0.4 2,-0.3 -3,-0.1 -9,-0.1 -0.926 29.0 150.9-110.5 112.8 9.0 73.6 217.6 45 46 A L - 0 0 57 -2,-0.6 2,-0.2 -11,-0.2 -32,-0.1 -0.998 47.6-103.9-145.8 148.2 11.4 74.0 214.7 46 47 A N - 0 0 48 -2,-0.3 37,-2.6 36,-0.0 38,-0.4 -0.502 36.7-152.5 -69.1 129.5 12.6 72.3 211.6 47 48 A L B -J 82 0C 2 35,-0.3 35,-0.3 -2,-0.2 34,-0.1 -0.601 25.1 -95.0 -99.2 164.5 16.0 70.6 212.0 48 49 A S > + 0 0 0 33,-2.6 4,-0.9 -2,-0.2 33,-0.2 -0.703 33.4 174.6 -90.9 108.1 18.5 69.9 209.2 49 50 A P H > S+ 0 0 2 0, 0.0 4,-3.1 0, 0.0 -1,-0.2 0.806 87.0 62.5 -74.7 -27.3 18.5 66.5 207.4 50 51 A Q H > S+ 0 0 1 36,-0.4 4,-2.3 1,-0.2 5,-0.3 0.826 96.0 59.7 -64.0 -32.2 21.1 67.9 205.0 51 52 A N H > S+ 0 0 0 35,-0.3 4,-1.7 2,-0.2 -1,-0.2 0.922 111.2 40.0 -61.4 -43.9 23.3 68.3 208.0 52 53 A L H X S+ 0 0 0 -4,-0.9 4,-2.8 2,-0.2 -2,-0.2 0.934 111.3 56.5 -70.9 -48.7 23.1 64.6 208.6 53 54 A V H < S+ 0 0 2 -4,-3.1 -2,-0.2 1,-0.2 -1,-0.2 0.876 118.9 32.2 -52.2 -43.1 23.3 63.7 204.9 54 55 A D H < S+ 0 0 14 -4,-2.3 41,-0.3 -5,-0.1 -1,-0.2 0.743 128.2 36.8 -88.8 -24.1 26.6 65.5 204.5 55 56 A b H < S+ 0 0 13 -4,-1.7 2,-1.9 -5,-0.3 -3,-0.2 0.757 84.5 91.5-102.2 -29.1 28.1 65.0 208.0 56 57 A V >< - 0 0 8 -4,-2.8 3,-1.9 -5,-0.2 5,-0.4 -0.498 51.5-176.1 -71.7 85.5 27.1 61.5 209.2 57 58 A S T 3 S+ 0 0 108 -2,-1.9 -1,-0.2 1,-0.3 -4,-0.0 0.728 76.9 64.4 -55.8 -23.8 30.2 59.7 207.9 58 59 A E T 3 S+ 0 0 131 11,-0.1 -1,-0.3 -3,-0.1 2,-0.1 0.726 100.9 59.1 -73.1 -22.7 28.8 56.3 209.1 59 60 A N S < S- 0 0 18 -3,-1.9 6,-0.2 -7,-0.2 3,-0.1 -0.307 87.7-119.0 -96.6-176.6 25.9 56.6 206.7 60 61 A D > - 0 0 103 4,-2.7 3,-3.3 1,-0.3 2,-0.2 -0.081 33.7-135.6-118.8 35.5 25.9 56.9 202.9 61 62 A G G > S+ 0 0 2 -5,-0.4 3,-1.0 1,-0.3 -1,-0.3 -0.289 90.6 3.5 52.9-114.8 24.3 60.3 202.3 62 63 A a G 3 S+ 0 0 41 1,-0.2 -40,-1.4 -2,-0.2 -1,-0.3 0.452 127.3 71.5 -79.7 -0.8 21.8 59.8 199.5 63 64 A G G < S- 0 0 52 -3,-3.3 -1,-0.2 1,-0.3 -2,-0.2 0.562 112.0 -89.9 -90.9 -10.5 22.7 56.1 199.5 64 65 A G < - 0 0 27 -3,-1.0 -4,-2.7 -42,-0.5 -1,-0.3 -0.379 47.0-173.9 120.7 159.8 21.0 55.2 202.7 65 66 A G - 0 0 25 -6,-0.2 2,-0.3 -2,-0.1 -6,-0.1 -0.991 26.7 -89.9-177.8 170.6 21.7 55.1 206.4 66 67 A Y > - 0 0 142 -2,-0.3 4,-1.3 1,-0.1 3,-0.1 -0.763 22.2-140.9 -99.2 141.5 20.8 54.2 210.0 67 68 A M H > S+ 0 0 9 -2,-0.3 4,-2.7 1,-0.2 5,-0.2 0.855 102.6 58.1 -67.5 -35.3 19.0 56.6 212.4 68 69 A T H > S+ 0 0 18 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.887 103.3 52.2 -64.7 -35.2 21.2 55.5 215.3 69 70 A N H > S+ 0 0 36 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.897 110.6 50.9 -64.4 -37.7 24.3 56.5 213.5 70 71 A A H X S+ 0 0 0 -4,-1.3 4,-2.1 2,-0.2 -2,-0.2 0.940 109.0 47.6 -64.1 -51.2 22.7 59.9 212.9 71 72 A F H X S+ 0 0 0 -4,-2.7 4,-2.1 1,-0.2 37,-0.2 0.910 111.8 52.1 -57.3 -41.7 21.8 60.5 216.6 72 73 A Q H X S+ 0 0 60 -4,-2.2 4,-2.7 1,-0.2 5,-0.3 0.881 105.5 55.7 -61.5 -40.2 25.3 59.5 217.5 73 74 A Y H X S+ 0 0 33 -4,-1.9 4,-2.6 1,-0.2 -1,-0.2 0.939 109.2 45.6 -57.8 -50.6 26.7 62.0 215.0 74 75 A V H X>S+ 0 0 0 -4,-2.1 5,-2.3 2,-0.2 4,-1.0 0.869 112.2 52.8 -62.4 -37.6 24.7 64.8 216.7 75 76 A Q H ><5S+ 0 0 70 -4,-2.1 3,-0.5 2,-0.2 -2,-0.2 0.968 114.9 38.3 -62.6 -56.4 25.8 63.7 220.2 76 77 A K H 3<5S+ 0 0 138 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.909 118.3 50.6 -62.2 -40.9 29.5 63.6 219.4 77 78 A N H 3<5S- 0 0 52 -4,-2.6 -1,-0.2 -5,-0.3 -2,-0.2 0.704 105.2-134.7 -70.0 -18.1 29.2 66.8 217.3 78 79 A R T <<5S+ 0 0 176 -4,-1.0 2,-0.2 -3,-0.5 -3,-0.2 0.822 71.0 23.3 65.7 32.7 27.3 68.4 220.2 79 80 A G < - 0 0 0 -5,-2.3 2,-0.3 -6,-0.2 26,-0.2 -0.764 56.8-136.5 156.1 159.0 24.7 69.7 217.8 80 81 A I E -K 104 0D 0 24,-1.7 23,-2.5 -2,-0.2 24,-1.3 -0.999 32.2-118.4-139.9 137.6 22.6 69.8 214.6 81 82 A D E -K 102 0D 0 -2,-0.3 -33,-2.6 21,-0.3 21,-0.2 -0.220 29.8-107.8 -71.2 164.5 21.7 72.9 212.5 82 83 A S B > -J 47 0C 25 19,-1.4 4,-1.1 -35,-0.3 -35,-0.3 -0.353 34.3-104.5 -82.7 171.5 18.2 74.0 211.9 83 84 A E T 4 S+ 0 0 33 -37,-2.6 3,-0.4 1,-0.2 -36,-0.1 0.929 121.0 48.7 -63.8 -43.8 16.6 73.6 208.5 84 85 A D T 4 S+ 0 0 141 -38,-0.4 -1,-0.2 1,-0.2 -37,-0.1 0.692 110.9 49.1 -71.3 -20.1 17.0 77.3 207.6 85 86 A A T 4 S+ 0 0 47 1,-0.2 -1,-0.2 -3,-0.2 -2,-0.2 0.679 129.6 21.6 -90.0 -19.8 20.6 77.4 208.7 86 87 A Y S < S- 0 0 18 -4,-1.1 -36,-0.4 -3,-0.4 -35,-0.3 -0.570 90.7-156.6-149.3 72.4 21.5 74.3 206.7 87 88 A P - 0 0 73 0, 0.0 2,-0.3 0, 0.0 -3,-0.1 -0.173 20.3-108.1 -58.1 142.8 18.8 73.9 203.9 88 89 A Y + 0 0 45 1,-0.1 -5,-0.0 2,-0.1 -40,-0.0 -0.550 36.4 170.8 -74.7 128.4 18.0 70.6 202.2 89 90 A V - 0 0 81 -2,-0.3 -1,-0.1 2,-0.2 3,-0.1 0.455 46.0-117.5-119.0 -5.3 19.2 70.3 198.6 90 91 A G S S+ 0 0 26 1,-0.2 2,-0.3 -71,-0.1 -69,-0.1 0.653 83.4 81.1 78.8 15.2 18.6 66.6 197.8 91 92 A Q S S- 0 0 110 -70,-0.1 -2,-0.2 -71,-0.0 2,-0.2 -0.996 83.1-101.9-151.2 148.7 22.2 65.7 197.2 92 93 A E + 0 0 102 -2,-0.3 2,-0.3 -32,-0.1 -38,-0.1 -0.493 46.4 166.8 -72.3 138.0 25.2 64.8 199.2 93 94 A E - 0 0 79 -43,-0.2 3,-0.1 -2,-0.2 -32,-0.0 -0.857 44.7 -63.9-140.6 173.4 27.7 67.6 199.7 94 95 A S - 0 0 89 -2,-0.3 2,-0.5 1,-0.1 -39,-0.1 -0.253 67.4 -89.2 -60.2 150.5 30.8 68.3 201.8 95 96 A b + 0 0 66 -41,-0.3 -1,-0.1 1,-0.1 -44,-0.1 -0.487 48.9 173.4 -65.6 113.9 30.0 68.6 205.6 96 97 A M + 0 0 128 -2,-0.5 -1,-0.1 -3,-0.1 -45,-0.1 -0.166 8.8 167.8-114.6 40.3 29.2 72.2 206.2 97 98 A Y - 0 0 49 -46,-0.1 -11,-0.0 1,-0.1 -17,-0.0 -0.311 17.0-161.7 -57.0 131.4 28.1 72.1 209.9 98 99 A N > - 0 0 75 1,-0.1 3,-1.6 -13,-0.0 4,-0.2 -0.972 15.6-153.3-120.6 121.2 27.9 75.6 211.3 99 100 A P G > S+ 0 0 86 0, 0.0 3,-1.0 0, 0.0 -1,-0.1 0.756 95.2 62.1 -63.5 -24.6 27.9 76.1 215.1 100 101 A T G 3 S+ 0 0 130 1,-0.2 0, 0.0 -15,-0.1 0, 0.0 0.581 102.1 52.7 -77.8 -7.3 26.0 79.4 214.8 101 102 A G G < S+ 0 0 10 -3,-1.6 -19,-1.4 -16,-0.1 -1,-0.2 0.365 76.5 137.0-105.6 1.8 23.1 77.4 213.3 102 103 A K E < +K 81 0D 96 -3,-1.0 -21,-0.3 -21,-0.2 3,-0.1 -0.300 18.7 165.3 -53.3 117.0 22.9 75.0 216.1 103 104 A A E + 0 0 26 -23,-2.5 2,-0.3 1,-0.3 -1,-0.2 0.579 60.0 12.2-110.9 -19.8 19.2 74.5 216.9 104 105 A A E -K 80 0D 7 -24,-1.3 -24,-1.7 -30,-0.0 -1,-0.3 -0.989 56.8-144.3-157.0 164.9 19.5 71.3 219.0 105 106 A K - 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