==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=21-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HORMONE/GROWTH FACTOR 16-MAR-05 1Z4S . COMPND 2 MOLECULE: HEPARIN-BINDING GROWTH FACTOR 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR J.LEE,M.BLABER . 555 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 26667.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 335 60.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 187 33.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 28 5.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 50 9.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 67 12.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 6 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 25 5 0 8 6 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1DA H 0 0 231 0, 0.0 2,-0.3 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 43.7 26.5 62.7 -24.2 2 1EA H - 0 0 57 1,-0.2 103,-0.0 0, 0.0 102,-0.0 -0.844 360.0 -86.1-129.3 166.6 25.8 65.3 -21.5 3 1FA H - 0 0 58 -2,-0.3 -1,-0.2 1,-0.1 0, 0.0 -0.060 30.8-138.7 -61.9 173.4 24.3 68.8 -21.4 4 1GA F + 0 0 119 2,-0.1 2,-0.8 85,-0.1 -1,-0.1 -0.142 47.0 140.4-132.7 39.7 26.7 71.7 -22.1 5 2 A N - 0 0 99 85,-0.2 85,-3.1 0, 0.0 88,-0.1 -0.781 37.6-161.6 -84.2 112.6 25.7 74.4 -19.5 6 3 A L - 0 0 65 -2,-0.8 83,-0.1 83,-0.2 -2,-0.1 -0.718 10.7-128.5-100.6 147.5 29.0 75.8 -18.4 7 4 A P - 0 0 14 0, 0.0 47,-0.1 0, 0.0 83,-0.1 -0.421 29.2-106.4 -86.5 166.9 29.7 77.8 -15.3 8 5 A P + 0 0 126 0, 0.0 -2,-0.0 0, 0.0 82,-0.0 0.976 58.7 175.4 -56.8 -56.2 31.6 81.2 -15.3 9 6 A G - 0 0 20 1,-0.1 2,-0.4 126,-0.1 -3,-0.0 0.543 25.7-140.3 62.8 146.8 34.8 79.7 -13.9 10 7 A N + 0 0 94 3,-0.1 38,-0.2 1,-0.1 -1,-0.1 -0.975 19.2 175.6-144.0 124.8 38.2 81.3 -13.2 11 8 A Y + 0 0 61 -2,-0.4 -1,-0.1 1,-0.1 4,-0.0 0.254 69.4 77.1-112.8 10.8 41.5 79.6 -13.8 12 9 A K S S+ 0 0 175 1,-0.1 -1,-0.1 2,-0.1 37,-0.0 0.836 95.2 37.3 -89.3 -37.6 43.7 82.6 -13.0 13 10 A K S S- 0 0 116 1,-0.1 35,-0.3 34,-0.0 -1,-0.1 -0.879 89.3-104.0-118.2 149.4 43.6 82.6 -9.2 14 11 A P - 0 0 48 0, 0.0 124,-0.6 0, 0.0 2,-0.3 -0.238 40.2-164.0 -65.2 159.0 43.5 79.6 -6.8 15 12 A K E -AB 46 137A 14 31,-2.9 31,-2.7 122,-0.2 2,-0.5 -0.865 23.2-123.8-139.3 172.3 40.2 78.7 -5.1 16 13 A L E - B 0 136A 6 120,-2.1 120,-1.9 -2,-0.3 2,-0.7 -0.955 26.7-140.4-121.3 109.9 38.7 76.7 -2.2 17 14 A L E - B 0 135A 4 -2,-0.5 8,-1.8 27,-0.4 2,-0.5 -0.601 20.4-163.1 -75.0 111.4 36.2 74.2 -3.4 18 15 A Y E -CB 24 134A 80 116,-2.1 116,-1.6 -2,-0.7 6,-0.2 -0.832 6.4-144.4 -98.4 128.1 33.3 74.2 -0.9 19 16 A C E > - B 0 133A 0 4,-3.4 3,-1.5 -2,-0.5 114,-0.2 -0.539 20.1-123.2 -89.0 155.7 30.9 71.3 -0.8 20 17 A S T 3 S+ 0 0 21 112,-1.6 110,-0.1 109,-0.7 -1,-0.1 0.703 110.5 68.4 -69.8 -17.4 27.2 71.8 0.0 21 18 A N T 3 S- 0 0 18 108,-0.3 -1,-0.3 111,-0.2 109,-0.1 0.558 123.9-102.2 -75.6 -8.7 27.7 69.2 2.8 22 20 A G S < S+ 0 0 11 -3,-1.5 2,-0.3 1,-0.3 -2,-0.1 0.713 82.6 118.5 94.9 23.4 29.8 71.8 4.6 23 21 A H - 0 0 6 -4,-0.1 -4,-3.4 89,-0.1 2,-0.4 -0.893 55.8-134.9-123.5 154.2 33.3 70.5 3.8 24 22 A F E -CD 18 36A 12 12,-2.9 12,-1.7 -2,-0.3 2,-0.3 -0.824 32.5-112.1-101.9 143.8 36.3 71.8 1.9 25 23 A L E - D 0 35A 3 -8,-1.8 2,-0.4 -2,-0.4 10,-0.2 -0.595 38.9-166.2 -76.9 135.1 38.0 69.4 -0.5 26 24 A R E - D 0 34A 49 8,-2.6 8,-2.0 -2,-0.3 2,-0.5 -0.986 18.4-169.2-131.8 135.4 41.5 68.5 0.8 27 25 A I E - D 0 33A 0 16,-1.5 6,-0.2 -2,-0.4 34,-0.2 -0.900 16.8-153.9-123.4 101.2 44.5 66.8 -0.9 28 26 A L > - 0 0 42 4,-2.4 3,-2.2 -2,-0.5 48,-0.1 -0.326 28.2-111.3 -71.6 154.5 47.3 65.8 1.5 29 27 A P T 3 S+ 0 0 68 0, 0.0 -1,-0.1 0, 0.0 31,-0.0 0.750 116.6 61.2 -56.0 -29.1 50.9 65.5 0.3 30 28 A D T 3 S- 0 0 117 2,-0.1 -2,-0.1 1,-0.0 46,-0.0 0.469 124.4-101.7 -79.7 -1.2 50.8 61.7 0.7 31 29 A G S < S+ 0 0 14 -3,-2.2 45,-2.5 1,-0.3 2,-0.4 0.513 73.3 143.7 96.1 4.8 48.0 61.5 -1.8 32 30 A T - 0 0 71 43,-0.2 -4,-2.4 -4,-0.0 2,-0.4 -0.658 33.2-157.0 -83.5 132.1 45.0 61.1 0.5 33 31 A V E +D 27 0A 13 -2,-0.4 85,-0.4 41,-0.4 2,-0.3 -0.887 31.8 122.0-109.3 137.0 41.8 62.9 -0.6 34 32 A D E -D 26 0A 29 -8,-2.0 -8,-2.6 -2,-0.4 2,-0.3 -0.926 50.2 -85.8-167.6-169.2 39.1 63.8 1.9 35 33 A G E -D 25 0A 10 81,-2.7 2,-0.3 -2,-0.3 -10,-0.2 -0.908 29.2-178.4-123.1 150.1 37.0 66.6 3.5 36 34 A T E -D 24 0A 21 -12,-1.7 -12,-2.9 -2,-0.3 80,-0.1 -0.996 26.3-150.2-144.2 147.2 37.5 69.1 6.3 37 35 A R + 0 0 153 -2,-0.3 2,-0.9 -14,-0.2 -1,-0.1 0.435 68.1 109.0 -94.3 -0.9 35.4 71.8 7.9 38 36 A D > - 0 0 75 1,-0.2 3,-1.4 -14,-0.1 -2,-0.0 -0.676 48.0-170.5 -83.0 107.5 38.5 73.8 8.9 39 37 A R T 3 S+ 0 0 138 -2,-0.9 -1,-0.2 1,-0.3 5,-0.1 0.666 84.9 59.7 -69.5 -17.0 38.7 77.0 6.8 40 38 A S T 3 S+ 0 0 94 -3,-0.0 -1,-0.3 2,-0.0 -2,-0.1 0.402 76.6 123.1 -92.8 2.4 42.2 77.7 8.1 41 39 A D < - 0 0 21 -3,-1.4 3,-0.4 1,-0.1 4,-0.0 -0.287 57.3-144.7 -62.3 149.0 43.6 74.4 6.8 42 40 A Q S S+ 0 0 151 1,-0.2 -1,-0.1 2,-0.1 19,-0.1 0.075 89.2 64.0-106.5 24.5 46.6 74.8 4.5 43 41 A H S S+ 0 0 49 18,-0.1 -16,-1.5 17,-0.0 -1,-0.2 0.263 84.7 74.4-123.7 5.3 45.9 71.8 2.2 44 42 A I + 0 0 1 -3,-0.4 2,-0.7 -18,-0.2 -27,-0.4 0.441 62.1 109.4 -99.5 -1.2 42.6 73.1 0.7 45 43 A Q - 0 0 54 -29,-0.1 16,-0.5 -18,-0.1 2,-0.3 -0.677 51.7-178.0 -78.4 115.7 44.1 75.8 -1.6 46 44 A L E -AE 15 60A 2 -31,-2.7 -31,-2.9 -2,-0.7 2,-0.4 -0.831 20.9-148.4-117.7 154.9 43.5 74.3 -5.0 47 45 A Q E - E 0 59A 66 12,-2.4 12,-2.6 -2,-0.3 2,-0.3 -0.985 12.6-161.8-125.1 127.1 44.3 75.6 -8.6 48 46 A L E - E 0 58A 5 -2,-0.4 2,-0.3 -35,-0.3 10,-0.2 -0.752 7.9-177.8-106.6 155.6 42.2 74.8 -11.6 49 47 A S E - E 0 57A 52 8,-1.3 8,-1.6 -2,-0.3 2,-0.3 -0.980 25.5-118.6-153.1 140.1 43.1 75.0 -15.3 50 48 A A E + E 0 56A 52 -2,-0.3 6,-0.2 6,-0.2 3,-0.1 -0.616 23.4 175.2 -83.3 133.5 41.3 74.5 -18.6 51 49 A E E S- 0 0 106 4,-2.4 2,-0.3 1,-0.4 5,-0.2 0.584 77.7 -19.0-105.8 -19.3 42.5 71.8 -20.9 52 50 A S E > S- E 0 55A 62 3,-1.2 2,-0.8 0, 0.0 3,-0.6 -0.926 99.4 -55.4-169.0 178.0 39.6 72.4 -23.4 53 51 A V T 3 S+ 0 0 108 -2,-0.3 3,-0.1 1,-0.2 -3,-0.0 -0.596 129.7 1.1 -72.3 112.0 36.2 74.0 -23.3 54 52 A G T 3 S+ 0 0 7 -2,-0.8 34,-3.5 1,-0.2 2,-0.4 0.156 110.1 101.3 98.9 -21.3 34.5 72.2 -20.4 55 53 A E E < +EF 52 87A 39 -3,-0.6 -4,-2.4 32,-0.2 -3,-1.2 -0.841 48.6 174.0-100.8 134.5 37.4 69.9 -19.4 56 54 A V E -EF 50 86A 0 30,-2.8 30,-2.0 -2,-0.4 2,-0.3 -0.871 27.2-138.3-136.9 170.0 39.6 70.8 -16.4 57 55 A Y E -E 49 0A 38 -8,-1.6 -8,-1.3 -2,-0.3 2,-0.6 -0.932 13.6-148.7-122.3 147.6 42.4 69.6 -14.1 58 56 A I E -E 48 0A 2 26,-0.4 8,-2.2 -2,-0.3 2,-0.2 -0.914 22.6-175.6-122.5 101.7 42.4 70.1 -10.3 59 57 A K E -EG 47 65A 84 -12,-2.6 -12,-2.4 -2,-0.6 6,-0.2 -0.634 15.0-132.5 -99.3 155.4 45.9 70.6 -9.0 60 58 A S E -E 46 0A 8 4,-2.1 -14,-0.1 -2,-0.2 -16,-0.1 -0.475 28.6-104.1 -98.7 172.5 47.1 70.9 -5.4 61 59 A T S S+ 0 0 83 -16,-0.5 -15,-0.1 1,-0.2 -1,-0.1 0.842 123.5 46.5 -63.8 -33.8 49.5 73.4 -3.7 62 61 A T S S- 0 0 74 -19,-0.1 -1,-0.2 2,-0.1 -34,-0.0 0.734 128.8 -94.4 -81.4 -24.0 52.2 70.7 -3.6 63 62 A G S S+ 0 0 15 1,-0.3 2,-0.3 -3,-0.0 -2,-0.1 0.715 75.7 138.3 114.2 35.6 51.6 69.7 -7.2 64 63 A Q - 0 0 0 -37,-0.1 -4,-2.1 15,-0.0 2,-0.4 -0.845 41.3-139.5-112.0 148.9 49.3 66.8 -7.1 65 64 A Y E -GH 59 77A 41 12,-2.9 12,-3.1 -2,-0.3 -6,-0.2 -0.892 18.8-120.7-110.1 135.5 46.3 66.1 -9.4 66 65 A L E + H 0 76A 0 -8,-2.2 -8,-0.3 -2,-0.4 2,-0.3 -0.458 43.8 171.6 -68.8 143.0 42.9 64.8 -8.2 67 66 A A E - H 0 75A 0 8,-1.7 8,-1.6 -2,-0.1 2,-0.4 -0.935 30.8-135.5-148.6 171.3 42.1 61.5 -10.0 68 67 A M E - H 0 74A 1 15,-1.1 6,-0.2 -2,-0.3 34,-0.1 -0.982 20.6-145.3-135.8 121.2 39.6 58.6 -10.0 69 68 A D > - 0 0 29 4,-2.6 3,-2.0 -2,-0.4 4,-0.1 -0.163 39.3 -88.7 -77.7 175.1 40.7 54.9 -10.4 70 69 A T T 3 S+ 0 0 77 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.620 126.3 56.1 -61.6 -13.6 38.9 52.1 -12.2 71 70 A D T 3 S- 0 0 12 2,-0.1 -1,-0.3 50,-0.0 -2,-0.0 0.501 122.0-102.1 -96.0 -6.5 36.9 51.3 -9.1 72 71 A G S < S+ 0 0 0 -3,-2.0 49,-1.8 1,-0.3 2,-0.4 0.652 75.0 142.5 94.2 18.1 35.5 54.9 -8.7 73 72 A L - 0 0 47 47,-0.2 -4,-2.6 -4,-0.1 -1,-0.3 -0.775 45.0-131.7 -99.2 138.5 38.0 55.8 -5.9 74 73 A L E +H 68 0A 22 -2,-0.4 -41,-0.4 -6,-0.2 2,-0.3 -0.628 34.0 156.6 -87.1 141.1 39.6 59.3 -5.5 75 74 A Y E -H 67 0A 73 -8,-1.6 -8,-1.7 -2,-0.3 2,-0.7 -0.983 42.8-105.8-158.5 158.1 43.3 59.8 -5.0 76 75 A G E -H 66 0A 11 -45,-2.5 2,-0.3 -2,-0.3 -10,-0.2 -0.820 35.6-159.9 -94.8 117.0 46.0 62.4 -5.4 77 76 A S E -H 65 0A 17 -12,-3.1 -12,-2.9 -2,-0.7 -46,-0.1 -0.653 17.7-145.5 -95.8 149.0 48.4 61.7 -8.3 78 77 A Q S S+ 0 0 117 -2,-0.3 -1,-0.1 -14,-0.2 -47,-0.0 0.832 86.8 35.4 -81.0 -34.5 51.9 63.1 -8.8 79 78 A T S S- 0 0 97 -14,-0.1 2,-0.1 -15,-0.0 -1,-0.1 -0.920 90.6-107.6-121.7 147.2 51.8 63.2 -12.6 80 79 A P + 0 0 64 0, 0.0 2,-0.2 0, 0.0 -13,-0.1 -0.455 46.6 154.7 -73.2 143.6 48.8 64.0 -14.8 81 80 A N > - 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