==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 13-JUN-05 1ZZ0 . COMPND 2 MOLECULE: HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE; . SOURCE 2 ORGANISM_SCIENTIFIC: ALCALIGENACEAE BACTERIUM; . AUTHOR T.K.NIELSEN,C.HILDMANN,A.DICKMANNS,A.SCHWIENHORST,R.FICNER . 1468 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 42004.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 1023 69.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 165 11.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 28 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 8 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 6 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 87 5.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 188 12.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 433 29.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 24 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 8 4 0 8 0 4 4 8 4 0 0 0 0 4 0 4 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 8 4 0 11 9 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 8 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 4 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A A 0 0 76 0, 0.0 129,-2.7 0, 0.0 130,-1.1 0.000 360.0 360.0 360.0 109.9 -11.8 -26.3 -30.4 2 3 A I E -a 131 0A 17 55,-0.4 57,-3.1 127,-0.2 130,-0.3 -0.912 360.0-144.7-112.0 118.3 -8.9 -28.4 -31.6 3 4 A G E -ab 132 59A 0 128,-2.6 130,-2.4 -2,-0.5 2,-0.4 -0.486 12.3-166.8 -84.3 155.9 -6.7 -30.0 -28.9 4 5 A Y E -ab 133 60A 5 55,-1.9 57,-2.6 128,-0.2 2,-0.5 -0.977 2.9-160.3-145.7 124.2 -3.0 -30.5 -29.3 5 6 A V E +a 134 0A 0 128,-2.3 130,-2.5 -2,-0.4 2,-0.3 -0.940 22.1 150.9-113.1 122.4 -0.7 -32.6 -27.1 6 7 A W - 0 0 40 -2,-0.5 2,-0.4 55,-0.4 57,-0.3 -0.986 18.1-169.2-134.8 141.7 3.1 -32.2 -26.9 7 8 A N > - 0 0 37 128,-0.4 3,-1.9 -2,-0.3 4,-0.5 -0.998 28.7-128.8-127.6 136.2 5.2 -33.1 -23.9 8 9 A T G > S+ 0 0 21 -2,-0.4 3,-1.6 1,-0.3 -1,-0.1 0.823 107.6 62.3 -47.5 -38.8 8.9 -32.1 -23.7 9 10 A L G > S+ 0 0 3 1,-0.3 3,-2.0 2,-0.2 4,-0.3 0.722 84.3 73.8 -67.9 -24.0 9.8 -35.7 -22.7 10 11 A Y G X S+ 0 0 0 -3,-1.9 3,-0.5 1,-0.3 -1,-0.3 0.813 99.3 49.7 -52.1 -30.6 8.5 -37.0 -26.1 11 12 A G G < S+ 0 0 6 -3,-1.6 -1,-0.3 -4,-0.5 -2,-0.2 0.432 101.2 63.6 -88.4 1.4 11.7 -35.4 -27.4 12 13 A W G < + 0 0 7 -3,-2.0 -1,-0.2 -4,-0.1 -2,-0.2 0.268 65.2 137.5-107.3 4.6 13.9 -37.0 -24.8 13 14 A V < - 0 0 20 -3,-0.5 2,-0.8 -4,-0.3 89,-0.1 -0.331 52.9-134.0 -54.7 131.4 13.3 -40.6 -25.8 14 15 A D + 0 0 21 1,-0.1 -1,-0.1 24,-0.1 3,-0.1 -0.826 28.9 174.8 -97.0 107.7 16.7 -42.4 -25.7 15 16 A T - 0 0 18 -2,-0.8 3,-0.5 1,-0.3 2,-0.2 0.383 39.4-133.2 -94.0 2.0 17.1 -44.4 -28.9 16 17 A G - 0 0 12 1,-0.2 -1,-0.3 19,-0.1 19,-0.2 -0.544 34.1 -60.7 88.2-148.8 20.7 -45.4 -28.1 17 18 A T S S+ 0 0 26 -2,-0.2 15,-2.3 -3,-0.1 -1,-0.2 0.289 98.9 91.2-127.4 9.0 23.7 -45.3 -30.3 18 19 A G S S- 0 0 2 -3,-0.5 4,-0.2 13,-0.2 5,-0.1 -0.424 73.9-125.0 -95.8 176.2 22.8 -47.7 -33.1 19 20 A S S S- 0 0 7 2,-0.4 17,-2.4 16,-0.2 18,-0.2 0.785 93.3 -31.7 -85.7 -36.9 21.1 -47.1 -36.5 20 21 A L S S+ 0 0 9 1,-1.3 -2,-0.1 15,-0.2 2,-0.1 0.240 140.0 30.1-152.4 -72.5 18.3 -49.6 -36.0 21 22 A A S S- 0 0 36 1,-0.2 -1,-1.3 -4,-0.1 -2,-0.4 -0.349 112.4 -70.1 -75.7 179.5 19.6 -52.4 -34.0 22 23 A A - 0 0 36 76,-0.5 -1,-0.2 -4,-0.2 -3,-0.1 -0.266 58.1 -92.1 -66.0 155.2 22.4 -51.6 -31.4 23 24 A A - 0 0 11 -5,-0.1 2,-0.3 -3,-0.1 817,-0.2 -0.395 47.2-169.0 -57.9 149.5 25.9 -50.6 -32.6 24 25 A N B > -H 29 0B 48 5,-1.3 5,-2.6 1,-0.1 4,-0.4 -0.897 17.9-158.2-152.3 117.4 28.0 -53.8 -32.8 25 26 A L T > 5S+ 0 0 11 815,-0.5 3,-1.1 -2,-0.3 -1,-0.1 0.878 91.8 51.9 -71.1 -40.6 31.7 -53.8 -33.3 26 27 A T T 3 5S+ 0 0 105 1,-0.3 -1,-0.2 2,-0.1 815,-0.0 0.892 112.7 47.1 -64.2 -34.2 32.2 -57.3 -34.6 27 28 A A T 3 5S- 0 0 25 2,-0.1 -1,-0.3 674,-0.1 -2,-0.2 0.538 113.5-125.9 -74.5 -10.7 29.5 -56.6 -37.2 28 29 A R T < 5 + 0 0 36 -3,-1.1 2,-1.0 -4,-0.4 -3,-0.2 0.828 54.0 156.4 61.0 38.9 31.3 -53.3 -37.9 29 30 A M B < -H 24 0B 25 -5,-2.6 -5,-1.3 -7,-0.1 -1,-0.2 -0.838 37.6-141.9 -89.9 99.1 28.1 -51.4 -37.3 30 31 A Q - 0 0 20 -2,-1.0 -11,-0.1 -7,-0.2 718,-0.0 -0.353 18.6-106.4 -65.0 139.7 29.6 -48.0 -36.4 31 32 A P - 0 0 27 0, 0.0 2,-0.3 0, 0.0 -13,-0.2 -0.243 39.1-162.5 -60.3 156.0 27.8 -46.0 -33.7 32 33 A I - 0 0 27 -15,-2.3 3,-0.2 1,-0.1 -9,-0.1 -0.983 26.1-129.2-145.1 149.5 25.9 -43.0 -34.9 33 34 A S S S+ 0 0 38 -2,-0.3 2,-0.6 1,-0.2 -1,-0.1 0.889 97.1 43.2 -67.1 -40.9 24.4 -39.9 -33.2 34 35 A H S S- 0 0 70 -17,-0.1 -1,-0.2 4,-0.1 -17,-0.1 -0.906 72.5-153.7-117.8 105.8 20.9 -40.3 -34.7 35 36 A H > - 0 0 11 -2,-0.6 3,-2.1 -19,-0.2 -16,-0.2 -0.278 40.2-101.8 -58.1 155.4 19.2 -43.6 -34.8 36 37 A L T 3 S+ 0 0 16 -17,-2.4 -16,-0.1 1,-0.3 -1,-0.1 0.881 125.9 44.6 -49.0 -38.0 16.6 -43.9 -37.5 37 38 A A T 3 S+ 0 0 17 -18,-0.2 -1,-0.3 -22,-0.1 -17,-0.1 0.171 81.5 151.8 -96.5 17.9 13.8 -43.3 -34.9 38 39 A H X - 0 0 36 -3,-2.1 3,-1.3 1,-0.1 4,-0.4 -0.147 54.1-121.2 -52.2 140.6 15.6 -40.4 -33.1 39 40 A P T 3> S+ 0 0 5 0, 0.0 4,-2.3 0, 0.0 3,-0.3 0.633 97.3 85.3 -62.5 -14.8 13.1 -38.0 -31.4 40 41 A D H 3> S+ 0 0 38 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.836 81.9 61.8 -58.7 -29.7 14.3 -35.0 -33.4 41 42 A T H <> S+ 0 0 10 -3,-1.3 4,-1.1 1,-0.2 -1,-0.2 0.969 110.7 36.9 -61.9 -46.9 12.0 -35.8 -36.3 42 43 A K H > S+ 0 0 10 -4,-0.4 4,-2.3 -3,-0.3 -1,-0.2 0.866 114.3 56.3 -75.4 -31.7 8.9 -35.5 -34.2 43 44 A R H X S+ 0 0 13 -4,-2.3 4,-3.0 1,-0.2 -1,-0.2 0.908 103.8 54.8 -65.7 -39.0 10.3 -32.5 -32.2 44 45 A R H X S+ 0 0 18 -4,-2.6 4,-1.7 -5,-0.2 -1,-0.2 0.838 106.5 52.1 -62.9 -31.9 10.8 -30.7 -35.5 45 46 A F H X S+ 0 0 0 -4,-1.1 4,-2.3 -5,-0.2 -2,-0.2 0.970 110.9 46.7 -65.8 -50.7 7.1 -31.3 -36.3 46 47 A H H X S+ 0 0 34 -4,-2.3 4,-2.3 1,-0.2 -2,-0.2 0.925 111.0 52.2 -53.8 -46.7 6.2 -29.8 -32.9 47 48 A E H X S+ 0 0 12 -4,-3.0 4,-3.5 1,-0.2 -1,-0.2 0.869 109.1 49.7 -65.4 -31.4 8.5 -26.8 -33.4 48 49 A L H X S+ 0 0 2 -4,-1.7 4,-2.5 2,-0.2 6,-0.4 0.879 105.4 56.6 -73.3 -37.0 6.9 -26.1 -36.8 49 50 A V H <>S+ 0 0 0 -4,-2.3 6,-1.9 1,-0.2 5,-0.6 0.941 116.7 38.1 -54.4 -43.6 3.4 -26.2 -35.3 50 51 A C H ><5S+ 0 0 25 -4,-2.3 3,-1.6 4,-0.2 -2,-0.2 0.961 118.3 45.9 -71.9 -51.8 4.6 -23.5 -33.0 51 52 A A H 3<5S+ 0 0 10 -4,-3.5 -3,-0.2 1,-0.3 -2,-0.2 0.753 107.9 57.3 -68.4 -29.0 6.8 -21.5 -35.4 52 53 A S T 3<5S- 0 0 19 -4,-2.5 -1,-0.3 -5,-0.2 -2,-0.2 0.631 112.2-119.5 -72.1 -13.0 4.2 -21.5 -38.1 53 54 A G T X 5S+ 0 0 26 -3,-1.6 3,-1.4 -4,-0.3 4,-0.3 0.366 82.4 122.3 80.4 4.1 1.7 -19.9 -35.7 54 55 A Q G > < + 0 0 0 -5,-0.6 3,-2.6 -6,-0.4 -4,-0.2 0.882 62.6 69.5 -60.2 -34.6 -0.6 -22.9 -36.1 55 56 A I G > S+ 0 0 35 -6,-1.9 3,-1.6 1,-0.3 -1,-0.3 0.772 85.8 68.3 -55.0 -26.0 -0.3 -23.2 -32.3 56 57 A E G < S+ 0 0 152 -3,-1.4 -1,-0.3 1,-0.3 -2,-0.2 0.655 101.0 47.3 -68.8 -16.0 -2.4 -20.0 -31.9 57 58 A H G < S+ 0 0 93 -3,-2.6 -55,-0.4 -4,-0.3 2,-0.3 0.185 103.5 81.8-107.9 8.6 -5.4 -21.9 -33.3 58 59 A L S < S- 0 0 14 -3,-1.6 -55,-0.2 -4,-0.1 74,-0.0 -0.829 73.5-131.1-116.4 153.8 -4.9 -24.9 -31.1 59 60 A T E -b 3 0A 56 -57,-3.1 -55,-1.9 -2,-0.3 2,-0.1 -0.923 29.6-135.4-101.8 103.8 -5.9 -25.7 -27.5 60 61 A P E -b 4 0A 92 0, 0.0 2,-0.5 0, 0.0 -55,-0.2 -0.425 21.2-165.5 -63.4 131.6 -2.8 -27.1 -25.7 61 62 A I - 0 0 11 -57,-2.6 -55,-0.4 -2,-0.1 2,-0.3 -0.986 16.7-128.4-121.9 126.1 -3.7 -30.1 -23.7 62 63 A A - 0 0 71 -2,-0.5 -55,-0.1 -57,-0.1 2,-0.1 -0.550 24.3-119.4 -74.9 134.6 -1.2 -31.5 -21.1 63 64 A A - 0 0 13 -2,-0.3 2,-0.4 -57,-0.3 53,-0.2 -0.397 23.0-151.6 -67.3 148.3 -0.4 -35.2 -21.3 64 65 A V - 0 0 80 51,-0.3 55,-0.2 48,-0.2 54,-0.2 -0.989 28.0-104.0-121.9 134.3 -1.4 -37.1 -18.1 65 66 A A - 0 0 47 -2,-0.4 47,-0.2 50,-0.1 2,-0.1 -0.406 36.8-116.4 -63.2 128.5 0.7 -40.3 -17.4 66 67 A A - 0 0 1 45,-2.3 49,-0.1 -2,-0.1 2,-0.1 -0.414 30.9-132.6 -61.3 135.5 -1.2 -43.5 -18.2 67 68 A T > - 0 0 72 -2,-0.1 4,-2.5 1,-0.1 5,-0.2 -0.388 24.4-103.8 -86.0 167.1 -1.9 -45.5 -15.1 68 69 A D H > S+ 0 0 55 1,-0.2 4,-2.9 2,-0.2 5,-0.2 0.926 125.2 54.3 -53.3 -44.4 -1.2 -49.3 -14.8 69 70 A A H > S+ 0 0 58 1,-0.2 4,-0.8 2,-0.2 -1,-0.2 0.910 107.9 49.3 -56.9 -44.6 -5.1 -49.7 -15.1 70 71 A D H >4 S+ 0 0 21 1,-0.2 3,-1.0 2,-0.2 4,-0.4 0.949 113.9 45.1 -59.2 -49.8 -5.0 -47.7 -18.4 71 72 A I H >X S+ 0 0 0 -4,-2.5 4,-1.9 1,-0.2 3,-1.8 0.896 105.9 60.7 -62.5 -40.3 -2.2 -49.8 -19.8 72 73 A L H 3< S+ 0 0 72 -4,-2.9 -1,-0.2 1,-0.3 -2,-0.2 0.627 88.7 71.3 -68.3 -12.8 -3.8 -53.1 -18.7 73 74 A R T << S+ 0 0 79 -3,-1.0 -1,-0.3 -4,-0.8 -2,-0.2 0.754 118.2 20.5 -68.3 -23.0 -6.8 -52.4 -20.9 74 75 A A T <4 S+ 0 0 0 -3,-1.8 2,-0.3 -4,-0.4 -2,-0.2 0.642 124.7 49.3-113.6 -24.2 -4.5 -53.1 -23.9 75 76 A H S < S- 0 0 2 -4,-1.9 71,-0.2 71,-0.1 70,-0.1 -0.832 77.3-104.7-129.8 154.7 -1.6 -55.0 -22.5 76 77 A S > - 0 0 25 69,-2.4 4,-2.1 -2,-0.3 5,-0.2 -0.415 30.9-120.0 -72.5 154.3 -0.7 -58.0 -20.3 77 78 A A H > S+ 0 0 69 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.881 114.9 56.7 -59.4 -38.6 0.6 -57.6 -16.7 78 79 A A H > S+ 0 0 75 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.885 105.7 50.4 -62.7 -38.7 3.8 -59.4 -17.7 79 80 A H H > S+ 0 0 5 2,-0.2 4,-2.1 1,-0.2 -2,-0.2 0.959 111.8 46.9 -63.6 -51.4 4.4 -56.9 -20.5 80 81 A L H X S+ 0 0 6 -4,-2.1 4,-2.1 1,-0.2 -2,-0.2 0.918 113.2 48.9 -54.8 -45.2 3.9 -53.9 -18.1 81 82 A E H X S+ 0 0 117 -4,-2.7 4,-2.3 1,-0.2 -1,-0.2 0.894 109.0 53.3 -62.9 -40.0 6.2 -55.5 -15.5 82 83 A N H X S+ 0 0 52 -4,-2.4 4,-2.4 2,-0.2 -1,-0.2 0.885 108.2 49.9 -61.9 -35.9 8.8 -56.2 -18.2 83 84 A M H X S+ 0 0 0 -4,-2.1 4,-2.4 2,-0.2 -2,-0.2 0.877 108.5 52.4 -73.2 -36.2 8.8 -52.5 -19.2 84 85 A K H X S+ 0 0 52 -4,-2.1 4,-1.5 -5,-0.2 -1,-0.2 0.917 109.9 50.9 -59.5 -44.3 9.2 -51.4 -15.6 85 86 A R H X S+ 0 0 128 -4,-2.3 4,-0.5 2,-0.2 3,-0.3 0.949 113.0 42.6 -57.6 -51.4 12.2 -53.8 -15.4 86 87 A V H >< S+ 0 0 0 -4,-2.4 3,-1.4 1,-0.2 6,-0.2 0.917 111.5 55.6 -66.1 -41.7 14.0 -52.4 -18.5 87 88 A S H 3< S+ 0 0 6 -4,-2.4 18,-3.3 1,-0.3 -1,-0.2 0.819 103.2 56.2 -59.6 -33.9 13.2 -48.8 -17.5 88 89 A N H 3< S+ 0 0 133 -4,-1.5 -1,-0.3 -3,-0.3 -2,-0.2 0.596 82.2 107.8 -76.2 -14.9 14.9 -49.3 -14.1 89 90 A L S X< S- 0 0 68 -3,-1.4 3,-1.2 -4,-0.5 16,-0.2 -0.345 84.4-113.9 -63.3 149.0 18.2 -50.4 -15.7 90 91 A P T 3 S+ 0 0 100 0, 0.0 14,-0.2 0, 0.0 -1,-0.1 0.825 114.4 16.1 -62.3 -30.7 21.0 -47.7 -15.4 91 92 A T T 3 S- 0 0 58 1,-0.5 13,-0.2 12,-0.1 2,-0.1 0.154 107.1-126.7-120.0 19.8 21.1 -47.1 -19.2 92 93 A G < - 0 0 5 -3,-1.2 -1,-0.5 11,-0.3 2,-0.3 -0.417 33.2-148.8 65.1-147.3 17.7 -48.8 -20.0 93 94 A G E -I 102 0C 12 9,-2.5 9,-2.3 -2,-0.1 2,-0.1 -0.958 26.5 -46.0 166.9 175.7 18.0 -51.4 -22.7 94 95 A D E -I 101 0C 62 -2,-0.3 7,-0.2 7,-0.2 -2,-0.0 -0.444 43.2-142.8 -66.9 146.4 16.4 -53.2 -25.6 95 96 A T - 0 0 5 5,-2.3 53,-0.4 -2,-0.1 -1,-0.1 0.386 60.2 -70.0 -98.4 2.9 12.8 -54.3 -24.9 96 97 A G S S+ 0 0 67 4,-0.1 53,-0.1 51,-0.1 -2,-0.1 -0.101 117.2 69.4 147.5 -43.5 12.8 -57.7 -26.7 97 98 A D S S- 0 0 58 3,-0.1 52,-0.0 51,-0.1 -3,-0.0 0.463 95.3-114.8 -90.3 -0.8 13.0 -57.4 -30.5 98 99 A G S S+ 0 0 35 2,-0.2 -76,-0.5 -77,-0.0 -78,-0.1 0.286 106.2 61.2 86.3 -10.9 16.5 -56.1 -30.9 99 100 A I S S+ 0 0 30 -78,-0.2 2,-0.6 1,-0.1 50,-0.1 0.358 80.3 84.5-127.4 7.2 15.4 -52.7 -32.4 100 101 A T - 0 0 2 48,-0.1 -5,-2.3 50,-0.1 2,-0.3 -0.786 56.6-176.0-120.1 85.7 13.3 -51.2 -29.6 101 102 A M E -I 94 0C 45 -2,-0.6 2,-0.4 -7,-0.2 -7,-0.2 -0.563 8.2-166.7 -78.7 137.9 15.5 -49.3 -27.1 102 103 A M E -I 93 0C 6 -9,-2.3 -9,-2.5 -2,-0.3 3,-0.1 -1.000 18.5-136.9-120.6 131.0 14.0 -47.8 -24.0 103 104 A G > - 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