==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 13-JUN-05 1ZZ1 . COMPND 2 MOLECULE: HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE; . SOURCE 2 ORGANISM_SCIENTIFIC: ALCALIGENACEAE BACTERIUM; . AUTHOR T.K.NIELSEN,C.HILDMANN,A.DICKMANNS,A.SCHWIENHORST,R.FICNER . 1468 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 47715.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 1021 69.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 166 11.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 28 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 8 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 3 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 6 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 86 5.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 188 12.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 433 29.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 22 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 8 4 0 8 0 4 5 7 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 8 4 0 10 10 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 8 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 4 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A A 0 0 76 0, 0.0 129,-2.8 0, 0.0 130,-1.2 0.000 360.0 360.0 360.0 113.0 3.8 -39.3 56.4 2 3 A I E -a 131 0A 17 55,-0.5 57,-3.3 127,-0.2 130,-0.2 -0.860 360.0-148.4-109.8 119.4 3.6 -36.3 54.0 3 4 A G E -ab 132 59A 0 128,-2.4 130,-2.3 -2,-0.6 2,-0.4 -0.467 11.4-167.5 -84.1 151.0 1.6 -36.4 50.8 4 5 A Y E -ab 133 60A 5 55,-1.9 57,-2.8 128,-0.2 2,-0.5 -0.984 4.3-158.2-144.2 125.9 2.6 -34.5 47.7 5 6 A V E +a 134 0A 0 128,-2.2 130,-2.2 -2,-0.4 2,-0.3 -0.938 23.0 150.6-113.6 123.3 0.6 -33.8 44.5 6 7 A W - 0 0 47 -2,-0.5 2,-0.4 55,-0.4 57,-0.2 -0.986 17.5-170.8-139.2 132.5 2.0 -32.9 41.1 7 8 A N >> - 0 0 39 128,-0.4 3,-2.0 -2,-0.3 4,-0.5 -0.984 29.5-128.2-118.8 137.1 0.4 -33.7 37.8 8 9 A T G >4 S+ 0 0 88 -2,-0.4 3,-1.6 1,-0.3 4,-0.1 0.852 107.7 61.3 -46.8 -40.8 2.3 -33.2 34.6 9 10 A L G >4 S+ 0 0 35 1,-0.3 3,-1.5 2,-0.2 4,-0.3 0.698 85.1 74.1 -68.2 -18.2 -0.7 -31.2 33.2 10 11 A Y G X4 S+ 0 0 0 -3,-2.0 3,-0.5 1,-0.3 -1,-0.3 0.834 100.5 47.4 -57.6 -31.3 -0.4 -28.6 35.9 11 12 A G G << S+ 0 0 11 -3,-1.6 -1,-0.3 -4,-0.5 -2,-0.2 0.454 103.3 63.6 -87.7 -2.6 2.6 -27.5 33.9 12 13 A W G < + 0 0 179 -3,-1.5 -1,-0.2 -4,-0.1 -2,-0.2 0.296 63.9 134.5-104.7 4.7 0.7 -27.5 30.6 13 14 A V < - 0 0 32 -3,-0.5 2,-0.8 -4,-0.3 89,-0.0 -0.371 57.6-130.5 -55.6 121.9 -1.9 -24.8 31.4 14 15 A D + 0 0 121 1,-0.1 -1,-0.1 24,-0.1 3,-0.1 -0.739 30.6 176.1 -82.6 110.7 -1.9 -22.6 28.3 15 16 A T - 0 0 29 -2,-0.8 3,-0.4 1,-0.3 -1,-0.1 0.241 36.7-135.7-101.8 14.9 -1.5 -19.0 29.4 16 17 A G - 0 0 38 1,-0.2 -1,-0.3 19,-0.1 19,-0.3 -0.341 33.7 -64.7 75.3-151.2 -1.4 -17.7 25.8 17 18 A T S S+ 0 0 89 -3,-0.1 15,-2.6 17,-0.1 -1,-0.2 0.253 99.7 90.3-127.4 6.2 1.0 -15.1 24.4 18 19 A G S S- 0 0 1 -3,-0.4 4,-0.2 13,-0.2 5,-0.1 -0.312 76.2-119.8 -89.6-174.2 0.0 -12.0 26.4 19 20 A S S S- 0 0 5 2,-0.6 17,-2.6 16,-0.2 18,-0.2 0.781 91.6 -33.9 -93.7 -36.4 1.2 -10.6 29.7 20 21 A L S S+ 0 0 20 1,-1.6 2,-0.1 15,-0.2 -2,-0.1 0.159 141.1 35.2-154.7 -72.9 -2.0 -10.6 31.7 21 22 A A S S- 0 0 32 1,-0.2 -1,-1.6 79,-0.0 -2,-0.6 -0.403 113.2 -78.3 -70.5 169.9 -4.6 -9.9 29.1 22 23 A A - 0 0 75 -4,-0.2 -1,-0.2 -3,-0.1 -3,-0.2 -0.210 60.0 -81.8 -63.0 159.7 -4.0 -11.4 25.7 23 24 A A - 0 0 29 -5,-0.1 2,-0.3 -3,-0.1 7,-0.2 -0.327 52.6-163.8 -56.0 149.5 -1.4 -9.7 23.4 24 25 A N B >> -H 29 0B 63 5,-2.1 5,-2.6 1,-0.1 4,-0.7 -0.852 21.8-163.5-152.4 109.3 -3.2 -6.8 21.6 25 26 A L T >45S+ 0 0 141 -2,-0.3 3,-0.6 3,-0.2 -1,-0.1 0.893 92.6 50.9 -61.3 -45.6 -2.0 -5.0 18.5 26 27 A T T 345S+ 0 0 124 1,-0.3 -1,-0.2 2,-0.1 -2,-0.0 0.895 115.9 42.3 -61.8 -39.7 -4.2 -2.0 18.8 27 28 A A T 345S- 0 0 23 2,-0.1 -1,-0.3 1410,-0.1 -2,-0.2 0.565 112.3-125.6 -78.6 -8.2 -3.2 -1.4 22.5 28 29 A R T <<5 + 0 0 99 -4,-0.7 2,-0.9 -3,-0.6 -3,-0.2 0.869 53.8 156.2 57.1 44.3 0.4 -2.2 21.4 29 30 A M B < -H 24 0B 27 -5,-2.6 -5,-2.1 -7,-0.1 -1,-0.2 -0.883 37.8-141.0 -95.2 100.1 0.8 -5.0 24.0 30 31 A Q - 0 0 50 -2,-0.9 -11,-0.0 -7,-0.2 1118,-0.0 -0.332 19.6-102.3 -64.5 140.9 3.6 -7.0 22.3 31 32 A P - 0 0 75 0, 0.0 2,-0.3 0, 0.0 -13,-0.2 -0.276 41.3-167.9 -57.4 152.9 3.4 -10.9 22.5 32 33 A I - 0 0 30 -15,-2.6 3,-0.2 1,-0.1 -9,-0.1 -0.977 28.4-127.8-144.8 150.7 5.7 -12.4 25.1 33 34 A S S S+ 0 0 71 -2,-0.3 2,-0.7 1,-0.2 -1,-0.1 0.911 97.3 46.9 -65.1 -42.3 6.8 -16.1 25.8 34 35 A H S S- 0 0 59 -17,-0.1 -1,-0.2 -3,-0.1 -17,-0.1 -0.880 71.7-156.3-115.7 101.8 5.9 -16.0 29.5 35 36 A H > - 0 0 15 -2,-0.7 3,-2.3 -19,-0.3 -16,-0.2 -0.255 40.1-102.5 -56.0 152.2 2.6 -14.6 30.7 36 37 A L T 3 S+ 0 0 12 -17,-2.6 -16,-0.1 1,-0.3 -1,-0.1 0.877 125.5 41.8 -48.1 -40.1 2.7 -13.5 34.3 37 38 A A T 3 S+ 0 0 16 -18,-0.2 -1,-0.3 -22,-0.1 -17,-0.1 0.162 82.0 153.4 -98.5 18.5 0.9 -16.7 35.4 38 39 A H X - 0 0 40 -3,-2.3 3,-1.5 1,-0.2 4,-0.4 -0.172 53.2-123.2 -51.5 136.3 2.9 -19.0 33.1 39 40 A P T 3> S+ 0 0 5 0, 0.0 4,-2.6 0, 0.0 3,-0.3 0.649 98.0 84.6 -61.3 -13.5 2.9 -22.6 34.6 40 41 A D H 3> S+ 0 0 36 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.808 81.8 61.8 -57.8 -31.5 6.8 -22.6 34.6 41 42 A T H <> S+ 0 0 10 -3,-1.5 4,-1.1 2,-0.2 -1,-0.2 0.967 111.0 36.4 -61.5 -49.0 6.9 -20.9 38.0 42 43 A K H > S+ 0 0 10 -4,-0.4 4,-2.4 -3,-0.3 3,-0.2 0.877 114.4 57.1 -73.5 -34.0 5.0 -23.7 39.7 43 44 A R H X S+ 0 0 72 -4,-2.6 4,-2.9 1,-0.2 -1,-0.2 0.904 103.9 53.6 -61.0 -38.3 6.8 -26.3 37.6 44 45 A R H X S+ 0 0 14 -4,-2.7 4,-1.9 2,-0.2 -1,-0.2 0.830 106.3 52.5 -65.3 -32.2 10.1 -25.0 38.9 45 46 A F H X S+ 0 0 0 -4,-1.1 4,-2.4 -3,-0.2 -2,-0.2 0.960 111.3 47.2 -64.3 -54.2 8.8 -25.4 42.4 46 47 A H H X S+ 0 0 33 -4,-2.4 4,-1.9 1,-0.2 -2,-0.2 0.926 111.8 49.5 -48.9 -49.5 8.0 -29.0 41.6 47 48 A E H X S+ 0 0 72 -4,-2.9 4,-3.4 1,-0.2 -1,-0.2 0.864 109.8 51.5 -67.4 -32.4 11.4 -29.6 40.0 48 49 A L H X S+ 0 0 8 -4,-1.9 4,-2.5 2,-0.2 6,-0.4 0.887 103.8 57.6 -68.3 -37.3 13.1 -28.2 43.0 49 50 A V H <>S+ 0 0 0 -4,-2.4 6,-1.9 1,-0.2 5,-0.6 0.920 116.2 37.6 -56.9 -40.5 11.1 -30.5 45.3 50 51 A C H ><5S+ 0 0 49 -4,-1.9 3,-1.4 4,-0.2 -2,-0.2 0.940 117.1 47.1 -75.7 -50.1 12.6 -33.3 43.3 51 52 A A H 3<5S+ 0 0 51 -4,-3.4 -3,-0.2 1,-0.3 -2,-0.2 0.806 108.8 56.1 -66.0 -28.9 16.1 -32.0 42.7 52 53 A S T 3<5S- 0 0 18 -4,-2.5 -1,-0.3 -5,-0.2 -2,-0.2 0.548 113.6-117.1 -77.0 -10.4 16.6 -31.0 46.3 53 54 A G T X 5S+ 0 0 19 -3,-1.4 3,-1.4 -4,-0.2 4,-0.4 0.349 83.0 121.6 86.4 -3.6 15.8 -34.6 47.4 54 55 A Q G > < + 0 0 0 -5,-0.6 3,-2.6 -6,-0.4 4,-0.2 0.892 64.1 67.8 -56.9 -34.5 12.7 -33.6 49.3 55 56 A I G > S+ 0 0 45 -6,-1.9 3,-1.5 1,-0.3 -1,-0.3 0.814 89.4 64.3 -58.2 -27.6 10.6 -35.9 47.1 56 57 A E G < S+ 0 0 165 -3,-1.4 -1,-0.3 1,-0.3 -2,-0.2 0.706 104.2 47.4 -66.8 -18.9 12.4 -38.8 48.8 57 58 A H G < S+ 0 0 90 -3,-2.6 -55,-0.5 -4,-0.4 2,-0.3 0.261 104.2 80.7-104.0 5.2 10.7 -37.7 52.0 58 59 A L S < S- 0 0 13 -3,-1.5 -55,-0.2 -4,-0.2 74,-0.0 -0.841 73.0-132.6-115.3 152.9 7.3 -37.4 50.4 59 60 A T E -b 3 0A 54 -57,-3.3 -55,-1.9 -2,-0.3 2,-0.1 -0.911 30.8-132.1-100.0 105.8 4.5 -39.8 49.5 60 61 A P E -b 4 0A 89 0, 0.0 2,-0.5 0, 0.0 -55,-0.2 -0.380 21.6-163.6 -61.5 131.7 3.4 -39.0 45.9 61 62 A I - 0 0 4 -57,-2.8 -55,-0.4 -2,-0.1 2,-0.3 -0.984 15.2-131.0-121.4 121.3 -0.4 -38.8 45.7 62 63 A A - 0 0 67 -2,-0.5 -55,-0.1 -57,-0.1 2,-0.1 -0.552 22.7-120.0 -72.1 131.5 -2.0 -39.0 42.2 63 64 A A - 0 0 14 -2,-0.3 2,-0.4 -57,-0.2 53,-0.2 -0.411 24.1-153.7 -61.8 145.3 -4.5 -36.3 41.4 64 65 A V - 0 0 74 51,-0.3 2,-0.2 48,-0.2 55,-0.2 -0.991 28.0-102.5-121.5 137.1 -8.0 -37.6 40.6 65 66 A A - 0 0 48 -2,-0.4 47,-0.2 50,-0.1 46,-0.1 -0.421 38.7-118.8 -60.1 120.2 -10.3 -35.6 38.4 66 67 A A - 0 0 1 45,-2.3 2,-0.1 -2,-0.2 49,-0.1 -0.364 31.2-130.9 -58.8 136.7 -13.0 -33.8 40.5 67 68 A T > - 0 0 69 1,-0.1 4,-2.7 -3,-0.1 5,-0.2 -0.399 22.5-104.3 -84.8 165.0 -16.4 -35.0 39.6 68 69 A D H > S+ 0 0 56 2,-0.2 4,-3.0 1,-0.2 5,-0.2 0.944 126.3 53.3 -48.2 -50.1 -19.4 -32.8 38.9 69 70 A A H > S+ 0 0 56 1,-0.2 4,-0.6 2,-0.2 -1,-0.2 0.934 108.3 50.4 -52.0 -51.1 -20.7 -33.8 42.4 70 71 A D H >4 S+ 0 0 19 1,-0.2 3,-1.1 2,-0.2 4,-0.3 0.924 113.5 44.4 -50.1 -56.6 -17.3 -32.6 43.8 71 72 A I H >X S+ 0 0 0 -4,-2.7 4,-2.3 1,-0.2 3,-2.1 0.901 106.4 59.6 -58.6 -45.0 -17.5 -29.3 42.0 72 73 A L H 3< S+ 0 0 71 -4,-3.0 -1,-0.2 1,-0.3 -2,-0.2 0.570 90.3 71.4 -68.3 -6.2 -21.2 -28.6 42.8 73 74 A R T << S+ 0 0 75 -3,-1.1 -1,-0.3 -4,-0.6 -2,-0.2 0.745 118.4 19.1 -73.9 -23.6 -20.4 -28.7 46.6 74 75 A A T <4 S+ 0 0 0 -3,-2.1 2,-0.3 -4,-0.3 -2,-0.2 0.640 125.6 52.3-114.0 -27.0 -18.6 -25.4 46.1 75 76 A H S < S- 0 0 2 -4,-2.3 71,-0.2 1,-0.1 70,-0.1 -0.805 80.4-103.2-122.9 154.4 -20.1 -24.1 42.8 76 77 A S > - 0 0 16 69,-2.4 4,-1.7 -2,-0.3 5,-0.1 -0.248 30.4-120.1 -64.4 158.0 -23.4 -23.4 41.1 77 78 A A H > S+ 0 0 67 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.879 116.2 57.7 -64.2 -40.1 -24.8 -25.8 38.5 78 79 A A H > S+ 0 0 64 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.904 105.3 49.9 -57.3 -41.5 -24.8 -22.8 36.1 79 80 A H H > S+ 0 0 2 2,-0.2 4,-2.4 1,-0.2 -2,-0.2 0.939 111.1 47.0 -66.3 -49.4 -21.0 -22.3 36.7 80 81 A L H X S+ 0 0 6 -4,-1.7 4,-2.6 1,-0.2 -1,-0.2 0.932 113.8 49.7 -52.3 -51.1 -20.1 -26.0 36.1 81 82 A E H X S+ 0 0 119 -4,-2.5 4,-2.2 1,-0.2 -1,-0.2 0.873 110.5 50.2 -55.3 -43.5 -22.2 -26.0 32.9 82 83 A N H X S+ 0 0 48 -4,-2.2 4,-2.6 2,-0.2 -1,-0.2 0.848 109.6 49.7 -66.3 -39.2 -20.5 -22.8 31.7 83 84 A M H X S+ 0 0 0 -4,-2.4 4,-2.9 2,-0.2 -2,-0.2 0.900 110.6 50.5 -68.9 -40.0 -17.1 -24.2 32.3 84 85 A K H X S+ 0 0 58 -4,-2.6 4,-1.8 -5,-0.2 -2,-0.2 0.929 111.7 49.5 -56.6 -47.0 -18.1 -27.4 30.3 85 86 A R H X S+ 0 0 130 -4,-2.2 4,-0.8 2,-0.2 -2,-0.2 0.947 113.9 43.1 -57.4 -55.0 -19.4 -25.1 27.6 86 87 A V H >< S+ 0 0 0 -4,-2.6 3,-0.9 1,-0.2 -2,-0.2 0.917 113.6 51.9 -61.3 -44.2 -16.2 -23.0 27.4 87 88 A S H 3< S+ 0 0 4 -4,-2.9 18,-2.3 1,-0.2 19,-0.2 0.821 107.9 53.2 -62.5 -30.5 -14.0 -26.1 27.6 88 89 A N H 3< S+ 0 0 140 -4,-1.8 -1,-0.2 -5,-0.2 -2,-0.2 0.613 83.0 109.7 -81.8 -12.9 -15.9 -27.7 24.7 89 90 A L S X< S- 0 0 67 -3,-0.9 3,-0.7 -4,-0.8 16,-0.1 -0.354 84.5-112.1 -61.1 141.0 -15.4 -24.7 22.4 90 91 A P T 3 S+ 0 0 120 0, 0.0 14,-0.2 0, 0.0 -1,-0.1 0.776 117.4 18.4 -45.9 -38.3 -13.0 -25.4 19.4 91 92 A T T 3 S- 0 0 125 1,-0.5 13,-0.4 12,-0.1 2,-0.3 0.372 106.4-131.6-107.1 -7.9 -10.3 -23.0 20.8 92 93 A G < - 0 0 7 -3,-0.7 -1,-0.5 11,-0.3 2,-0.3 -0.652 38.4-176.2 74.2-145.4 -11.8 -22.9 24.3 93 94 A G E -I 102 0C 15 9,-3.2 9,-1.9 -2,-0.3 2,-0.2 -0.996 25.3 -5.9 156.5-161.0 -12.1 -19.3 25.5 94 95 A D E -I 101 0C 68 -2,-0.3 7,-0.2 7,-0.2 -2,-0.0 -0.505 41.5-154.4 -75.2 131.7 -12.9 -16.6 28.0 95 96 A T - 0 0 3 5,-2.7 53,-0.5 -2,-0.2 -1,-0.1 0.544 65.3 -71.7 -87.5 -7.8 -14.4 -18.0 31.2 96 97 A G S S+ 0 0 63 4,-0.3 -2,-0.1 51,-0.1 53,-0.1 0.202 119.8 69.6 148.2 -23.4 -16.2 -14.7 32.0 97 98 A D S S- 0 0 56 3,-0.2 4,-0.1 0, 0.0 53,-0.1 0.192 96.5-114.4-110.4 12.8 -13.8 -11.9 33.1 98 99 A G S S+ 0 0 47 2,-0.2 3,-0.1 1,-0.1 -4,-0.0 0.368 107.9 56.7 69.6 -2.6 -12.0 -11.3 29.8 99 100 A I S S+ 0 0 58 1,-0.1 2,-0.8 -78,-0.1 -1,-0.1 0.653 80.2 81.3-126.0 -36.1 -8.7 -12.5 31.3 100 101 A T - 0 0 2 48,-0.1 -5,-2.7 52,-0.1 -4,-0.3 -0.707 64.7-172.5 -87.8 112.9 -9.2 -16.1 32.7 101 102 A M E -I 94 0C 109 -2,-0.8 2,-0.4 -7,-0.2 -7,-0.2 -0.695 20.3-169.9-108.9 154.4 -8.9 -18.5 29.8 102 103 A M E -I 93 0C 10 -9,-1.9 -9,-3.2 -2,-0.3 3,-0.1 -0.973 18.4-141.7-141.0 128.2 -9.4 -22.2 29.3 103 104 A G > - 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