==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=7-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSPORT PROTEIN 06-FEB-09 2ZZ9 . COMPND 2 MOLECULE: AQUAPORIN-4; . SOURCE 2 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS; . AUTHOR K.TANI,T.MITSUMA,Y.HIROAKI,A.KAMEGAWA,K.NISHIKAWA, . 223 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10476.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 162 72.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 8 3.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 22 9.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 124 55.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 2.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 1 2 1 0 2 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 30 A W 0 0 207 0, 0.0 2,-0.3 0, 0.0 3,-0.1 0.000 360.0 360.0 360.0 -89.2 26.4 59.4 119.4 2 31 A T > - 0 0 68 1,-0.1 4,-3.2 0, 0.0 5,-0.3 -0.959 360.0-131.1-152.6 133.2 23.1 58.7 117.7 3 32 A Q H > S+ 0 0 148 -2,-0.3 4,-2.3 2,-0.2 5,-0.2 0.910 112.9 53.0 -53.5 -46.6 19.6 59.8 118.8 4 33 A A H > S+ 0 0 70 1,-0.2 4,-1.7 2,-0.2 3,-0.5 0.971 113.0 44.2 -47.6 -59.1 18.4 56.2 118.4 5 34 A F H > S+ 0 0 23 1,-0.2 4,-1.6 2,-0.2 -2,-0.2 0.886 114.1 48.4 -55.0 -45.6 21.3 55.1 120.7 6 35 A W H X S+ 0 0 116 -4,-3.2 4,-1.4 1,-0.2 -1,-0.2 0.706 105.9 57.0 -79.6 -19.1 20.8 57.8 123.2 7 36 A K H X S+ 0 0 103 -4,-2.3 4,-3.4 -3,-0.5 -1,-0.2 0.886 107.4 50.6 -62.8 -44.3 17.0 57.2 123.4 8 37 A A H X S+ 0 0 8 -4,-1.7 4,-2.4 2,-0.2 -2,-0.2 0.836 107.4 51.4 -67.6 -36.2 17.9 53.6 124.4 9 38 A V H X S+ 0 0 14 -4,-1.6 4,-2.0 2,-0.2 -1,-0.2 0.901 112.9 47.2 -63.3 -42.7 20.3 54.8 127.0 10 39 A T H X S+ 0 0 74 -4,-1.4 4,-2.8 2,-0.2 5,-0.3 0.957 111.4 49.2 -59.8 -54.6 17.4 57.0 128.3 11 40 A A H X S+ 0 0 5 -4,-3.4 4,-1.7 1,-0.2 -2,-0.2 0.879 111.4 51.6 -53.2 -40.7 15.0 54.1 128.1 12 41 A E H X S+ 0 0 1 -4,-2.4 4,-1.5 2,-0.2 -1,-0.2 0.858 110.9 47.2 -63.5 -39.5 17.6 52.0 130.0 13 42 A F H X S+ 0 0 61 -4,-2.0 4,-2.1 -3,-0.2 -2,-0.2 0.961 114.9 44.3 -67.6 -54.0 17.9 54.7 132.7 14 43 A L H X S+ 0 0 70 -4,-2.8 4,-1.3 1,-0.2 -2,-0.2 0.789 111.0 55.9 -57.1 -34.5 14.1 55.1 133.2 15 44 A A H X S+ 0 0 2 -4,-1.7 4,-2.8 -5,-0.3 -1,-0.2 0.895 110.4 41.1 -74.5 -42.6 13.5 51.4 133.2 16 45 A M H X S+ 0 0 0 -4,-1.5 4,-2.8 1,-0.2 5,-0.5 0.897 110.6 62.8 -66.6 -38.9 15.9 50.5 136.0 17 46 A L H X S+ 0 0 17 -4,-2.1 4,-0.7 1,-0.2 -2,-0.2 0.805 113.4 32.3 -52.4 -37.5 14.5 53.6 137.7 18 47 A I H X S+ 0 0 59 -4,-1.3 4,-3.4 3,-0.2 5,-0.5 0.873 115.6 57.2 -91.0 -46.1 11.0 52.1 137.8 19 48 A F H X>S+ 0 0 5 -4,-2.8 4,-2.8 1,-0.2 5,-0.6 0.967 115.0 36.6 -45.9 -65.3 12.1 48.5 138.2 20 49 A V H X>S+ 0 0 0 -4,-2.8 4,-1.1 1,-0.2 5,-0.5 0.843 119.2 50.1 -67.4 -32.3 14.1 49.2 141.4 21 50 A L H X5S+ 0 0 41 -4,-0.7 4,-1.3 -5,-0.5 -1,-0.2 0.977 118.9 35.8 -62.8 -55.2 11.7 51.8 142.7 22 51 A L H <5S+ 0 0 98 -4,-3.4 -2,-0.2 2,-0.2 -3,-0.2 0.952 129.3 31.4 -66.9 -49.4 8.6 49.6 142.3 23 52 A S H >X5S+ 0 0 0 -4,-2.8 3,-1.2 -5,-0.5 4,-0.7 0.856 121.1 47.1 -84.9 -37.4 10.0 46.2 143.1 24 53 A V H >< - 0 0 52 82,-0.6 2,-2.8 10,-0.1 3,-0.7 -0.879 3.7-148.0-115.0 102.3 8.3 45.9 155.6 30 59 A W T 3 S+ 0 0 169 -2,-0.6 82,-0.1 1,-0.3 -2,-0.0 -0.340 94.7 49.1 -76.3 73.0 5.3 47.7 157.2 31 60 A G T 3 S- 0 0 22 -2,-2.8 -1,-0.3 80,-0.2 80,-0.0 0.098 84.5-176.7 164.1 31.8 6.3 46.9 160.7 32 61 A G < 0 0 28 -3,-0.7 80,-0.1 1,-0.2 81,-0.0 -0.145 360.0 360.0 -58.0 144.6 10.0 47.9 160.6 33 62 A S 0 0 132 78,-0.1 -1,-0.2 0, 0.0 80,-0.0 0.729 360.0 360.0 19.8 360.0 12.4 47.3 163.6 34 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 35 64 A N 0 0 93 0, 0.0 -3,-0.1 0, 0.0 -6,-0.0 0.000 360.0 360.0 360.0 158.8 8.2 43.8 164.1 36 65 A P + 0 0 65 0, 0.0 -4,-0.1 0, 0.0 -6,-0.1 -0.177 360.0 177.3-177.8 90.1 7.2 42.3 161.7 37 66 A L - 0 0 33 1,-0.2 -7,-0.3 -8,-0.1 -5,-0.1 -0.426 37.2-136.9 85.3-118.3 6.7 41.4 158.1 38 67 A P - 0 0 85 0, 0.0 -1,-0.2 0, 0.0 -9,-0.0 -0.991 38.9-128.7 -73.4 2.8 5.1 38.9 157.8 39 68 A V - 0 0 37 1,-0.2 2,-0.9 2,-0.0 -10,-0.1 0.930 26.9-162.0 79.3 67.0 7.8 38.5 155.2 40 69 A D > - 0 0 87 1,-0.2 4,-2.0 2,-0.1 -1,-0.2 -0.754 15.6-178.7 -86.2 109.5 5.7 37.7 152.2 41 70 A M H > S+ 0 0 59 -2,-0.9 4,-3.9 2,-0.2 5,-0.4 0.980 82.4 58.7 -66.3 -56.8 7.8 36.1 149.5 42 71 A V H > S+ 0 0 82 1,-0.2 4,-1.8 2,-0.2 5,-0.2 0.795 110.4 47.7 -43.0 -34.2 4.9 35.7 147.0 43 72 A L H > S+ 0 0 77 2,-0.2 4,-2.3 3,-0.2 -1,-0.2 0.983 118.0 37.1 -67.7 -61.7 4.6 39.5 147.3 44 73 A I H X S+ 0 0 31 -4,-2.0 4,-2.2 1,-0.2 -2,-0.2 0.929 120.3 49.9 -60.1 -46.5 8.3 40.3 146.9 45 74 A S H X S+ 0 0 1 -4,-3.9 4,-1.1 1,-0.2 -1,-0.2 0.906 113.5 41.4 -57.7 -55.9 8.7 37.6 144.3 46 75 A L H X S+ 0 0 95 -4,-1.8 4,-2.3 -5,-0.4 5,-0.3 0.819 113.1 57.4 -62.6 -33.7 5.7 38.4 142.0 47 76 A C H X S+ 0 0 29 -4,-2.3 4,-1.6 1,-0.2 -2,-0.2 0.980 108.6 43.4 -60.1 -57.2 6.6 42.1 142.3 48 77 A F H X S+ 0 0 1 -4,-2.2 4,-0.7 -25,-0.2 -1,-0.2 0.654 119.0 43.3 -62.5 -26.6 10.1 41.7 141.0 49 78 A G H X S+ 0 0 1 -4,-1.1 4,-2.4 -5,-0.2 3,-0.2 0.910 115.6 44.4 -87.8 -52.0 9.2 39.4 138.2 50 79 A L H X S+ 0 0 83 -4,-2.3 4,-1.0 1,-0.2 -2,-0.2 0.732 110.2 59.5 -61.9 -24.8 6.1 41.2 136.9 51 80 A S H X S+ 0 0 19 -4,-1.6 4,-2.0 -5,-0.3 -1,-0.2 0.898 110.5 40.3 -71.8 -42.7 8.0 44.5 137.2 52 81 A I H X S+ 0 0 10 -4,-0.7 4,-2.6 2,-0.2 5,-0.3 0.845 113.0 54.8 -69.3 -39.4 10.6 43.3 134.8 53 82 A A H X S+ 0 0 10 -4,-2.4 4,-0.7 1,-0.2 -2,-0.2 0.760 112.4 45.7 -65.3 -26.8 7.9 41.7 132.7 54 83 A T H X S+ 0 0 77 -4,-1.0 4,-1.5 -5,-0.2 -2,-0.2 0.898 110.9 50.8 -82.8 -42.6 6.4 45.1 132.6 55 84 A M H X S+ 0 0 8 -4,-2.0 4,-1.9 1,-0.2 5,-0.4 0.874 109.5 49.1 -68.4 -39.8 9.5 47.0 131.9 56 85 A V H X S+ 0 0 21 -4,-2.6 4,-2.3 1,-0.2 5,-0.3 0.881 109.7 55.1 -65.4 -35.4 10.5 44.8 129.0 57 86 A Q H < S+ 0 0 138 -4,-0.7 -2,-0.2 -5,-0.3 -1,-0.2 0.837 114.1 39.5 -63.5 -32.3 7.0 45.3 127.7 58 87 A C H < S+ 0 0 61 -4,-1.5 -2,-0.2 -3,-0.1 -1,-0.2 0.761 135.8 14.2 -84.6 -28.9 7.4 49.2 127.9 59 88 A F H >X>S+ 0 0 35 -4,-1.9 3,-2.3 -5,-0.2 4,-0.9 0.516 90.5 99.9-131.3 -16.8 10.9 49.5 126.6 60 89 A G G ><5S+ 0 0 28 -4,-2.3 3,-0.7 -5,-0.4 4,-0.4 0.867 86.9 55.3 -44.9 -42.2 12.0 46.2 125.0 61 90 A H G 345S+ 0 0 157 -5,-0.3 -1,-0.3 1,-0.2 -2,-0.1 0.156 116.5 34.8 -78.4 18.0 11.3 47.7 121.6 62 91 A I G <45S+ 0 0 63 -3,-2.3 -51,-0.2 -54,-0.1 -1,-0.2 0.351 135.1 8.8-156.7 -3.7 13.6 50.7 122.2 63 92 A S T <<5S- 0 0 13 -4,-0.9 -3,-0.2 -3,-0.7 -2,-0.1 0.387 96.3-104.3-150.5 -42.7 16.6 49.6 124.3 64 93 A G < - 0 0 44 -5,-0.7 -4,-0.2 -4,-0.4 -3,-0.1 -0.040 45.2-106.0 128.7 -25.7 16.5 45.8 124.6 65 94 A G + 0 0 16 -6,-0.3 -5,-0.1 -10,-0.1 -9,-0.1 0.895 69.7 147.8 64.7 43.1 15.3 45.6 128.1 66 95 A H + 0 0 21 1,-0.1 5,-0.1 -6,-0.1 4,-0.1 0.990 9.5 158.8 -65.5 -61.9 18.7 44.6 129.4 67 96 A I + 0 0 5 4,-0.1 -1,-0.1 2,-0.1 120,-0.1 0.689 53.7 74.6 55.0 23.8 18.0 46.4 132.6 68 97 A N S >> S- 0 0 9 118,-0.1 4,-1.9 1,-0.1 3,-1.1 -0.732 73.3-144.5-173.7 107.3 20.7 44.3 134.2 69 98 A P H 3> S+ 0 0 0 0, 0.0 4,-3.1 0, 0.0 5,-0.2 0.769 101.8 58.7 -52.3 -36.5 24.5 44.6 133.7 70 99 A A H 3> S+ 0 0 0 2,-0.2 4,-2.7 1,-0.2 5,-0.2 0.903 107.8 47.1 -61.5 -40.2 25.1 40.9 133.8 71 100 A V H <> S+ 0 0 5 -3,-1.1 4,-2.1 2,-0.2 -1,-0.2 0.921 112.1 51.1 -63.6 -41.1 22.8 40.6 130.9 72 101 A T H X S+ 0 0 0 -4,-1.9 4,-2.0 2,-0.2 -2,-0.2 0.904 111.2 46.9 -63.3 -41.9 24.7 43.5 129.3 73 102 A V H X S+ 0 0 26 -4,-3.1 4,-3.2 1,-0.2 5,-0.2 0.931 113.8 47.6 -64.7 -45.5 28.0 41.7 129.9 74 103 A A H X S+ 0 0 0 -4,-2.7 4,-1.0 1,-0.2 -2,-0.2 0.798 109.2 55.7 -65.6 -29.3 26.6 38.4 128.5 75 104 A M H < S+ 0 0 19 -4,-2.1 6,-0.4 -5,-0.2 -1,-0.2 0.919 114.9 37.4 -66.2 -44.4 25.3 40.4 125.5 76 105 A V H >< S+ 0 0 25 -4,-2.0 3,-2.4 3,-0.2 -2,-0.2 0.913 112.7 55.2 -75.3 -45.4 28.8 41.7 124.7 77 106 A C H 3< S+ 0 0 62 -4,-3.2 -1,-0.2 1,-0.3 -2,-0.2 0.787 112.3 46.4 -57.3 -27.7 30.7 38.6 125.6 78 107 A T T 3< S- 0 0 11 -4,-1.0 -1,-0.3 -5,-0.2 -2,-0.2 0.326 122.9-112.2 -94.7 6.9 28.3 36.8 123.1 79 108 A R S < S+ 0 0 212 -3,-2.4 -3,-0.2 2,-0.2 -2,-0.1 0.976 81.9 117.4 52.9 92.0 29.0 39.7 120.6 80 109 A K S S+ 0 0 107 1,-0.4 2,-0.4 -5,-0.1 -4,-0.2 0.330 72.2 39.7-152.9 -27.4 25.6 41.4 120.4 81 110 A I S S- 0 0 30 -6,-0.4 -1,-0.4 -9,-0.1 -2,-0.2 -0.999 88.6-106.5-140.0 132.7 26.5 44.9 121.7 82 111 A S > - 0 0 59 -2,-0.4 4,-2.2 1,-0.1 5,-0.1 -0.111 29.1-116.7 -54.3 155.8 29.6 47.0 121.0 83 112 A I T 4 S+ 0 0 133 1,-0.2 4,-0.3 2,-0.2 -1,-0.1 0.828 118.8 43.6 -64.2 -30.9 32.2 47.3 123.8 84 113 A A T > S+ 0 0 54 2,-0.2 4,-0.8 1,-0.1 3,-0.3 0.757 110.0 53.9 -85.9 -30.2 31.4 51.1 123.9 85 114 A K T >4 S+ 0 0 41 1,-0.2 3,-0.7 2,-0.2 -2,-0.2 0.913 106.2 56.0 -64.8 -42.5 27.7 50.7 123.6 86 115 A S T 3X S+ 0 0 9 -4,-2.2 4,-1.3 1,-0.2 -1,-0.2 0.596 101.1 55.8 -68.2 -17.0 27.8 48.4 126.7 87 116 A V H 3> S+ 0 0 80 -3,-0.3 4,-1.1 -4,-0.3 -1,-0.2 0.750 102.5 55.3 -88.2 -24.1 29.6 51.0 128.8 88 117 A F H << S+ 0 0 75 -4,-0.8 4,-0.2 -3,-0.7 -2,-0.2 0.382 109.1 51.0 -84.9 1.8 26.8 53.6 128.3 89 118 A Y H > S+ 0 0 0 -3,-0.2 4,-2.7 -4,-0.1 5,-0.3 0.830 104.0 51.5-100.8 -53.0 24.3 51.0 129.5 90 119 A I H X S+ 0 0 45 -4,-1.3 4,-1.6 1,-0.2 -2,-0.1 0.890 115.2 44.3 -50.9 -47.3 25.9 49.9 132.8 91 120 A T H X S+ 0 0 69 -4,-1.1 4,-2.8 2,-0.3 5,-0.3 0.907 113.9 48.4 -67.6 -43.4 26.2 53.5 134.0 92 121 A A H > S+ 0 0 5 1,-0.2 4,-1.3 2,-0.2 -2,-0.2 0.804 116.9 45.1 -65.0 -29.6 22.7 54.4 132.8 93 122 A Q H X S+ 0 0 0 -4,-2.7 4,-1.2 2,-0.2 -2,-0.3 0.714 114.1 49.3 -79.2 -27.5 21.7 51.2 134.7 94 123 A C H X S+ 0 0 11 -4,-1.6 4,-1.2 -5,-0.3 -2,-0.2 0.766 116.4 39.6 -87.2 -25.7 23.8 52.2 137.6 95 124 A L H X S+ 0 0 93 -4,-2.8 4,-2.7 2,-0.2 5,-0.3 0.837 112.9 57.5 -82.4 -38.9 22.5 55.8 137.8 96 125 A G H X S+ 0 0 0 -4,-1.3 4,-0.7 -5,-0.3 -2,-0.2 0.882 111.6 41.8 -56.9 -43.2 18.9 54.6 137.1 97 126 A A H X S+ 0 0 0 -4,-1.2 4,-3.2 2,-0.2 3,-0.4 0.941 112.3 54.4 -68.2 -50.8 19.1 52.3 140.1 98 127 A I H X S+ 0 0 37 -4,-1.2 4,-1.5 1,-0.3 -2,-0.2 0.831 117.7 35.2 -54.2 -39.2 20.8 54.8 142.3 99 128 A I H X S+ 0 0 66 -4,-2.7 4,-2.2 2,-0.2 -1,-0.3 0.552 112.5 61.2 -95.5 -6.4 18.0 57.4 141.6 100 129 A G H X S+ 0 0 0 -4,-0.7 4,-1.3 -3,-0.4 -2,-0.2 0.908 114.9 34.2 -74.2 -48.8 15.4 54.8 141.5 101 130 A A H X S+ 0 0 0 -4,-3.2 4,-3.0 2,-0.2 -2,-0.2 0.868 117.4 58.2 -68.1 -41.6 16.2 53.9 145.1 102 131 A G H X S+ 0 0 22 -4,-1.5 4,-1.1 -5,-0.4 3,-0.4 0.977 107.6 43.5 -47.6 -67.7 16.9 57.6 145.7 103 132 A I H < S+ 0 0 72 -4,-2.2 3,-0.3 1,-0.2 -1,-0.2 0.850 115.8 52.4 -46.0 -39.6 13.5 58.6 144.7 104 133 A L H >X S+ 0 0 9 -4,-1.3 4,-2.6 1,-0.2 3,-2.1 0.915 97.8 64.3 -66.4 -42.7 12.2 55.7 146.8 105 134 A Y H 3< S+ 0 0 123 -4,-3.0 -1,-0.2 -3,-0.4 -2,-0.2 0.810 107.5 40.3 -51.8 -41.7 14.1 56.6 149.9 106 135 A L T 3< S+ 0 0 129 -4,-1.1 -1,-0.3 -3,-0.3 -2,-0.2 0.244 114.2 51.0 -98.1 10.5 12.2 59.9 150.4 107 136 A V T <4 S+ 0 0 106 -3,-2.1 -2,-0.2 -4,-0.1 -1,-0.2 0.594 96.2 75.9-116.5 -32.4 8.8 58.6 149.5 108 137 A T S < S- 0 0 14 -4,-2.6 4,-0.0 1,-0.1 -83,-0.0 -0.642 84.3-134.6 -73.4 140.5 8.9 55.6 151.8 109 138 A P - 0 0 81 0, 0.0 3,-0.4 0, 0.0 -1,-0.1 0.611 47.7 -56.9 -68.5-139.0 8.4 56.8 155.4 110 139 A P S S+ 0 0 130 0, 0.0 3,-0.0 0, 0.0 -2,-0.0 -0.216 117.0 82.3-103.9 38.4 10.5 55.7 158.5 111 140 A S > + 0 0 20 1,-0.1 3,-0.6 2,-0.0 -82,-0.6 0.227 59.9 96.8-117.9 5.6 9.8 51.9 158.0 112 141 A V G >> + 0 0 15 -3,-0.4 3,-2.2 1,-0.2 4,-1.3 0.681 41.7 119.9 -67.9 -18.8 12.6 51.5 155.4 113 142 A V G 34 + 0 0 88 1,-0.3 -1,-0.2 2,-0.2 -2,-0.0 0.590 52.0 85.3 -21.7 -41.7 15.0 50.4 158.1 114 143 A G G <4 S- 0 0 67 -3,-0.6 4,-0.4 1,-0.2 -1,-0.3 0.664 116.1-100.7 -36.2 -31.3 15.3 47.1 156.2 115 144 A G T <4 - 0 0 8 -3,-2.2 -1,-0.2 2,-0.2 -2,-0.2 0.676 55.3 -80.5 106.8 31.4 18.0 48.6 154.0 116 145 A L S < S- 0 0 0 -4,-1.3 -89,-0.2 1,-0.2 -88,-0.1 0.575 91.2 -61.6 50.5 10.0 15.7 49.4 151.1 117 146 A G S S- 0 0 19 -5,-0.2 2,-0.7 1,-0.2 -1,-0.2 0.952 71.2-172.5 77.8 70.3 16.4 45.7 150.4 118 147 A V - 0 0 22 -4,-0.4 -1,-0.2 73,-0.1 70,-0.1 -0.897 32.9-115.3 -92.8 114.0 20.1 45.5 149.9 119 148 A T + 0 0 11 -2,-0.7 2,-0.4 68,-0.1 61,-0.2 -0.275 44.2 177.7 -46.1 121.0 21.0 42.0 148.7 120 149 A T - 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