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         <PDBx:auth_seq_id>408</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>67</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="502">
         <PDBx:B_iso_or_equiv>10.24</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>-18.057</PDBx:Cartn_y>
         <PDBx:Cartn_z>5.579</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>408</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="503">
         <PDBx:B_iso_or_equiv>9.98</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_z>7.414</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>408</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>67</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="504">
         <PDBx:B_iso_or_equiv>10.24</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>-17.422</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.716</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>408</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="505">
         <PDBx:B_iso_or_equiv>9.68</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>-16.184</PDBx:Cartn_y>
         <PDBx:Cartn_z>6.563</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>408</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>67</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="506">
         <PDBx:B_iso_or_equiv>9.63</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>-16.487</PDBx:Cartn_y>
         <PDBx:Cartn_z>5.214</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>408</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>67</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="507">
         <PDBx:B_iso_or_equiv>9.96</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>-23.226</PDBx:Cartn_x>
         <PDBx:Cartn_y>-15.820</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.375</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OH</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>408</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OH</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>67</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="508">
         <PDBx:B_iso_or_equiv>14.41</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>-20.115</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.705</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>409</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>68</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="509">
         <PDBx:B_iso_or_equiv>16.02</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>-30.634</PDBx:Cartn_x>
         <PDBx:Cartn_y>-21.023</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.485</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>409</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>68</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="510">
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         <PDBx:Cartn_y>-22.270</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.938</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>409</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>68</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>-22.918</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.871</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>409</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>68</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:Cartn_z>7.744</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>409</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>7.597</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>409</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>7.209</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>409</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>409</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>409</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>6.928</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>409</PDBx:auth_seq_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0048</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0070</PDBx:U13>
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         <PDBx:U23>-0.0048</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0074</PDBx:U13>
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         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.2719</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.3375</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.3030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U12>-0.0347</PDBx:U12>
         <PDBx:U13>0.0075</PDBx:U13>
         <PDBx:U22>0.3356</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.3045</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="25">
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         <PDBx:U12>-0.0205</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.1607</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.1315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="26">
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         <PDBx:U12>-0.0174</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.1679</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="27">
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         <PDBx:U12>-0.0152</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1491</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="28">
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         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.1447</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.1203</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="29">
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         <PDBx:U12>-0.0174</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.1977</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.1661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="30">
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         <PDBx:U12>-0.0189</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.2347</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.2006</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.0191</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.2637</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.2256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.0165</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.2356</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.2035</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="33">
         <PDBx:U11>0.1482</PDBx:U11>
         <PDBx:U12>-0.0162</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.1474</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1215</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="34">
         <PDBx:U11>0.1506</PDBx:U11>
         <PDBx:U12>-0.0144</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1454</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1218</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="35">
         <PDBx:U11>0.1362</PDBx:U11>
         <PDBx:U12>-0.0133</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.1274</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="36">
         <PDBx:U11>0.1247</PDBx:U11>
         <PDBx:U12>-0.0115</PDBx:U12>
         <PDBx:U13>0.0024</PDBx:U13>
         <PDBx:U22>0.1155</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.0958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="37">
         <PDBx:U11>0.1781</PDBx:U11>
         <PDBx:U12>-0.0158</PDBx:U12>
         <PDBx:U13>0.0067</PDBx:U13>
         <PDBx:U22>0.1684</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="38">
         <PDBx:U11>0.2123</PDBx:U11>
         <PDBx:U12>-0.0169</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.2058</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.1792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="39">
         <PDBx:U11>0.2306</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>0.0097</PDBx:U13>
         <PDBx:U22>0.2270</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.2004</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="40">
         <PDBx:U11>0.2359</PDBx:U11>
         <PDBx:U12>-0.0154</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.2328</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.2041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="41">
         <PDBx:U11>0.2599</PDBx:U11>
         <PDBx:U12>-0.0128</PDBx:U12>
         <PDBx:U13>0.0133</PDBx:U13>
         <PDBx:U22>0.2614</PDBx:U22>
         <PDBx:U23>-0.0057</PDBx:U23>
         <PDBx:U33>0.2317</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="42">
         <PDBx:U11>0.1370</PDBx:U11>
         <PDBx:U12>-0.0146</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.1258</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1046</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="43">
         <PDBx:U11>0.1442</PDBx:U11>
         <PDBx:U12>-0.0131</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1302</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="44">
         <PDBx:U11>0.1290</PDBx:U11>
         <PDBx:U12>-0.0115</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.1193</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="45">
         <PDBx:U11>0.1274</PDBx:U11>
         <PDBx:U12>-0.0098</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.1175</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1005</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="46">
         <PDBx:U11>0.1672</PDBx:U11>
         <PDBx:U12>-0.0147</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.1492</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="47">
         <PDBx:U11>0.2018</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.1813</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1635</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="48">
         <PDBx:U11>0.2640</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.2403</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.2241</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="49">
         <PDBx:U11>0.2338</PDBx:U11>
         <PDBx:U12>-0.0133</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.2133</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1956</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="50">
         <PDBx:U11>0.2186</PDBx:U11>
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         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
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         <PDBx:U23>-0.0032</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:U23>-0.0032</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0024</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.1073</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0937</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="74">
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         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.1221</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1078</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>-0.0028</PDBx:U13>
         <PDBx:U22>0.1322</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.1179</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.1388</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.1251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.1398</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.1251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.1117</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0969</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U33>0.1037</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.1169</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1026</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.1184</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1045</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.1340</PDBx:U11>
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         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1353</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1194</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="83">
         <PDBx:U11>0.1521</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.1538</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1378</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="84">
         <PDBx:U11>0.1587</PDBx:U11>
         <PDBx:U12>-0.0039</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.1609</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="85">
         <PDBx:U11>0.1672</PDBx:U11>
         <PDBx:U12>-0.0032</PDBx:U12>
         <PDBx:U13>0.0005</PDBx:U13>
         <PDBx:U22>0.1708</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="86">
         <PDBx:U11>0.1296</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.1262</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1116</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="87">
         <PDBx:U11>0.1396</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>-0.0028</PDBx:U13>
         <PDBx:U22>0.1343</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1199</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="88">
         <PDBx:U11>0.1270</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>-0.0042</PDBx:U13>
         <PDBx:U22>0.1226</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="89">
         <PDBx:U11>0.1388</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>-0.0047</PDBx:U13>
         <PDBx:U22>0.1347</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1205</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="90">
         <PDBx:U11>0.1732</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.1652</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="91">
         <PDBx:U11>0.2252</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.2168</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.2013</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="92">
         <PDBx:U11>0.2896</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.2799</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.2646</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="93">
         <PDBx:U11>0.3541</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.3456</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.3296</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="94">
         <PDBx:U11>0.3703</PDBx:U11>
         <PDBx:U12>-0.0035</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.3616</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.3446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="95">
         <PDBx:U11>0.1213</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.1175</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1035</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="96">
         <PDBx:U11>0.1268</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>-0.0062</PDBx:U13>
         <PDBx:U22>0.1249</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1108</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="97">
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         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>-0.0057</PDBx:U13>
         <PDBx:U22>0.1225</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1085</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="98">
         <PDBx:U11>0.1275</PDBx:U11>
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         <PDBx:U13>-0.0064</PDBx:U13>
         <PDBx:U22>0.1303</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1158</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="99">
         <PDBx:U11>0.1325</PDBx:U11>
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         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.1299</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.1413</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.1269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.1451</PDBx:U11>
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         <PDBx:U13>-0.0091</PDBx:U13>
         <PDBx:U22>0.1439</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1295</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.1599</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.1604</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>-0.0101</PDBx:U13>
         <PDBx:U22>0.1622</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.1471</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="104">
         <PDBx:U11>0.1149</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>-0.0046</PDBx:U13>
         <PDBx:U22>0.1160</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="105">
         <PDBx:U11>0.1226</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
         <PDBx:U22>0.1256</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1122</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.1285</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1149</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="107">
         <PDBx:U11>0.1358</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1398</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1260</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="108">
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         <PDBx:U12>-0.0050</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.1264</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1134</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="109">
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         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.1330</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1202</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="110">
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         <PDBx:U13>-0.0023</PDBx:U13>
         <PDBx:U22>0.1465</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="111">
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         <PDBx:U12>-0.0035</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1460</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1334</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="112">
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         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1320</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1183</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="113">
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         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>-0.0033</PDBx:U13>
         <PDBx:U22>0.1510</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.1371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="114">
         <PDBx:U11>0.1554</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>-0.0044</PDBx:U13>
         <PDBx:U22>0.1531</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="115">
         <PDBx:U11>0.1809</PDBx:U11>
         <PDBx:U12>-0.0106</PDBx:U12>
         <PDBx:U13>-0.0041</PDBx:U13>
         <PDBx:U22>0.1763</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1613</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="116">
         <PDBx:U11>0.1614</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.1567</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="117">
         <PDBx:U11>0.1693</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.1654</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="118">
         <PDBx:U11>0.1927</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1875</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1734</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="119">
         <PDBx:U11>0.1817</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1768</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="120">
         <PDBx:U11>0.1508</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>0.1504</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.1353</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="121">
         <PDBx:U11>0.1569</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>-0.0070</PDBx:U13>
         <PDBx:U22>0.1563</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="122">
         <PDBx:U11>0.1720</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>-0.0076</PDBx:U13>
         <PDBx:U22>0.1751</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1577</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="123">
         <PDBx:U11>0.1664</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>-0.0071</PDBx:U13>
         <PDBx:U22>0.1728</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.1553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="124">
         <PDBx:U11>0.1601</PDBx:U11>
         <PDBx:U12>-0.0095</PDBx:U12>
         <PDBx:U13>-0.0082</PDBx:U13>
         <PDBx:U22>0.1597</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="125">
         <PDBx:U11>0.1768</PDBx:U11>
         <PDBx:U12>-0.0083</PDBx:U12>
         <PDBx:U13>-0.0090</PDBx:U13>
         <PDBx:U22>0.1801</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1635</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="126">
         <PDBx:U11>0.1946</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.1976</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.1788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="127">
         <PDBx:U11>0.2206</PDBx:U11>
         <PDBx:U12>-0.0162</PDBx:U12>
         <PDBx:U13>-0.0094</PDBx:U13>
         <PDBx:U22>0.2277</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.2070</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="128">
         <PDBx:U11>0.2021</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>-0.0103</PDBx:U13>
         <PDBx:U22>0.2156</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1939</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="129">
         <PDBx:U11>0.2046</PDBx:U11>
         <PDBx:U12>-0.0159</PDBx:U12>
         <PDBx:U13>-0.0099</PDBx:U13>
         <PDBx:U22>0.2225</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.1995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="130">
         <PDBx:U11>0.2707</PDBx:U11>
         <PDBx:U12>-0.0188</PDBx:U12>
         <PDBx:U13>-0.0108</PDBx:U13>
         <PDBx:U22>0.2763</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.2539</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="131">
         <PDBx:U11>0.3401</PDBx:U11>
         <PDBx:U12>-0.0205</PDBx:U12>
         <PDBx:U13>-0.0096</PDBx:U13>
         <PDBx:U22>0.3389</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.3173</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="132">
         <PDBx:U11>0.3968</PDBx:U11>
         <PDBx:U12>-0.0234</PDBx:U12>
         <PDBx:U13>-0.0087</PDBx:U13>
         <PDBx:U22>0.3957</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.3730</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="133">
         <PDBx:U11>0.4525</PDBx:U11>
         <PDBx:U12>-0.0262</PDBx:U12>
         <PDBx:U13>-0.0086</PDBx:U13>
         <PDBx:U22>0.4448</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.4216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="134">
         <PDBx:U11>0.4932</PDBx:U11>
         <PDBx:U12>-0.0242</PDBx:U12>
         <PDBx:U13>-0.0071</PDBx:U13>
         <PDBx:U22>0.4781</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.4571</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="135">
         <PDBx:U11>0.2107</PDBx:U11>
         <PDBx:U12>-0.0124</PDBx:U12>
         <PDBx:U13>-0.0115</PDBx:U13>
         <PDBx:U22>0.2244</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.2030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="136">
         <PDBx:U11>0.2325</PDBx:U11>
         <PDBx:U12>-0.0104</PDBx:U12>
         <PDBx:U13>-0.0124</PDBx:U13>
         <PDBx:U22>0.2514</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.2291</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="137">
         <PDBx:U11>0.1914</PDBx:U11>
         <PDBx:U12>-0.0095</PDBx:U12>
         <PDBx:U13>-0.0106</PDBx:U13>
         <PDBx:U22>0.2131</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.1913</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="138">
         <PDBx:U11>0.1946</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>-0.0110</PDBx:U13>
         <PDBx:U22>0.2221</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="139">
         <PDBx:U11>0.2980</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>-0.0132</PDBx:U13>
         <PDBx:U22>0.3136</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.2926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="140">
         <PDBx:U11>0.3594</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>-0.0138</PDBx:U13>
         <PDBx:U22>0.3782</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.3568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="141">
         <PDBx:U11>0.4174</PDBx:U11>
         <PDBx:U12>-0.0028</PDBx:U12>
         <PDBx:U13>-0.0153</PDBx:U13>
         <PDBx:U22>0.4324</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.4114</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="142">
         <PDBx:U11>0.4502</PDBx:U11>
         <PDBx:U12>-0.0033</PDBx:U12>
         <PDBx:U13>-0.0139</PDBx:U13>
         <PDBx:U22>0.4586</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.4398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="143">
         <PDBx:U11>0.5065</PDBx:U11>
         <PDBx:U12>-0.0016</PDBx:U12>
         <PDBx:U13>-0.0148</PDBx:U13>
         <PDBx:U22>0.5106</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.4923</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="144">
         <PDBx:U11>0.1537</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.1716</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="145">
         <PDBx:U11>0.1329</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>-0.0072</PDBx:U13>
         <PDBx:U22>0.1522</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1331</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="146">
         <PDBx:U11>0.1262</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>0.1451</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1260</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="147">
         <PDBx:U11>0.1275</PDBx:U11>
         <PDBx:U12>-0.0102</PDBx:U12>
         <PDBx:U13>-0.0042</PDBx:U13>
         <PDBx:U22>0.1464</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.1280</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="148">
         <PDBx:U11>0.1246</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>-0.0064</PDBx:U13>
         <PDBx:U22>0.1399</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
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         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="165">
         <PDBx:U11>0.1290</PDBx:U11>
         <PDBx:U12>-0.0112</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.1526</PDBx:U22>
         <PDBx:U23>-0.0057</PDBx:U23>
         <PDBx:U33>0.1336</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="166">
         <PDBx:U11>0.1285</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1458</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.1290</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="167">
         <PDBx:U11>0.1444</PDBx:U11>
         <PDBx:U12>-0.0099</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1592</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.1435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="168">
         <PDBx:U11>0.1287</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1555</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.1364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="169">
         <PDBx:U11>0.1324</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.1603</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.1410</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="170">
         <PDBx:U11>0.1376</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.1610</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.1434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="171">
         <PDBx:U11>0.1362</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>-0.0030</PDBx:U13>
         <PDBx:U22>0.1699</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.1482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="172">
         <PDBx:U11>0.1332</PDBx:U11>
         <PDBx:U12>-0.0031</PDBx:U12>
         <PDBx:U13>-0.0042</PDBx:U13>
         <PDBx:U22>0.1567</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="173">
         <PDBx:U11>0.1351</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>-0.0050</PDBx:U13>
         <PDBx:U22>0.1692</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1471</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="174">
         <PDBx:U11>0.1341</PDBx:U11>
         <PDBx:U12>-0.0028</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>0.1626</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="175">
         <PDBx:U11>0.1533</PDBx:U11>
         <PDBx:U12>-0.0012</PDBx:U12>
         <PDBx:U13>-0.0075</PDBx:U13>
         <PDBx:U22>0.1813</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.1610</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="176">
         <PDBx:U11>0.1194</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.1342</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.1177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="177">
         <PDBx:U11>0.1211</PDBx:U11>
         <PDBx:U12>-0.0100</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.1310</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1161</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="178">
         <PDBx:U11>0.1222</PDBx:U11>
         <PDBx:U12>-0.0115</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.1283</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.1136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="179">
         <PDBx:U11>0.1176</PDBx:U11>
         <PDBx:U12>-0.0104</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1205</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1068</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="180">
         <PDBx:U11>0.1241</PDBx:U11>
         <PDBx:U12>-0.0092</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.1329</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1183</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="181">
         <PDBx:U11>0.1272</PDBx:U11>
         <PDBx:U12>-0.0139</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.1334</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="182">
         <PDBx:U11>0.1398</PDBx:U11>
         <PDBx:U12>-0.0152</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1409</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.1254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="183">
         <PDBx:U11>0.1466</PDBx:U11>
         <PDBx:U12>-0.0146</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.1442</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1297</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="184">
         <PDBx:U11>0.1556</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1483</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.1343</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="185">
         <PDBx:U11>0.1496</PDBx:U11>
         <PDBx:U12>-0.0186</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1508</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.1337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="186">
         <PDBx:U11>0.1603</PDBx:U11>
         <PDBx:U12>-0.0206</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.1642</PDBx:U22>
         <PDBx:U23>-0.0062</PDBx:U23>
         <PDBx:U33>0.1460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="187">
         <PDBx:U11>0.1793</PDBx:U11>
         <PDBx:U12>-0.0218</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.1786</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.1609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="188">
         <PDBx:U11>0.1691</PDBx:U11>
         <PDBx:U12>-0.0210</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1803</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.1605</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="189">
         <PDBx:U11>0.1937</PDBx:U11>
         <PDBx:U12>-0.0238</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.1953</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.1764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="190">
         <PDBx:U11>0.1811</PDBx:U11>
         <PDBx:U12>-0.0226</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.1955</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.1744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="191">
         <PDBx:U11>0.1870</PDBx:U11>
         <PDBx:U12>-0.0242</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.1964</PDBx:U22>
         <PDBx:U23>-0.0075</PDBx:U23>
         <PDBx:U33>0.1758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="192">
         <PDBx:U11>0.1376</PDBx:U11>
         <PDBx:U12>-0.0143</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.1374</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.1229</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="193">
         <PDBx:U11>0.1467</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.1424</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1288</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="194">
         <PDBx:U11>0.1439</PDBx:U11>
         <PDBx:U12>-0.0112</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.1378</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="195">
         <PDBx:U11>0.1648</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1551</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1428</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="196">
         <PDBx:U11>0.1517</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.1503</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.1366</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="197">
         <PDBx:U11>0.1490</PDBx:U11>
         <PDBx:U12>-0.0151</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.1530</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.1379</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="198">
         <PDBx:U11>0.1412</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.1465</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.1312</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="199">
         <PDBx:U11>0.1265</PDBx:U11>
         <PDBx:U12>-0.0099</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.1231</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="200">
         <PDBx:U11>0.1268</PDBx:U11>
         <PDBx:U12>-0.0079</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.1230</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1108</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="201">
         <PDBx:U11>0.1249</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.1195</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1071</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="202">
         <PDBx:U11>0.1307</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1260</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.1133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="203">
         <PDBx:U11>0.1242</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.1238</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1116</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="204">
         <PDBx:U11>0.1334</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.1343</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="205">
         <PDBx:U11>0.1429</PDBx:U11>
         <PDBx:U12>-0.0081</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.1468</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1343</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="206">
         <PDBx:U11>0.1505</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.1495</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.1378</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="207">
         <PDBx:U11>0.1496</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1551</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="208">
         <PDBx:U11>0.1678</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.1675</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="209">
         <PDBx:U11>0.1627</PDBx:U11>
         <PDBx:U12>-0.0081</PDBx:U12>
         <PDBx:U13>0.0038</PDBx:U13>
         <PDBx:U22>0.1658</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1537</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="210">
         <PDBx:U11>0.1291</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1216</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="211">
         <PDBx:U11>0.1326</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1229</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="212">
         <PDBx:U11>0.1439</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1309</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1181</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="213">
         <PDBx:U11>0.1684</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.1555</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="214">
         <PDBx:U11>0.1390</PDBx:U11>
         <PDBx:U12>-0.0094</PDBx:U12>
         <PDBx:U13>0.0005</PDBx:U13>
         <PDBx:U22>0.1268</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.1137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="215">
         <PDBx:U11>0.1424</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1337</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.1201</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="216">
         <PDBx:U11>0.1386</PDBx:U11>
         <PDBx:U12>-0.0099</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.1340</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.1205</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="217">
         <PDBx:U11>0.1529</PDBx:U11>
         <PDBx:U12>-0.0134</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1430</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1286</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="218">
         <PDBx:U11>0.1411</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>-0.0015</PDBx:U13>
         <PDBx:U22>0.1393</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1252</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="219">
         <PDBx:U11>0.1573</PDBx:U11>
         <PDBx:U12>-0.0147</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1511</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1359</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="220">
         <PDBx:U11>0.1471</PDBx:U11>
         <PDBx:U12>-0.0132</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.1448</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1297</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="221">
         <PDBx:U11>0.1563</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.1575</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="222">
         <PDBx:U11>0.1479</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.1320</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1193</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="223">
         <PDBx:U11>0.1639</PDBx:U11>
         <PDBx:U12>-0.0035</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1441</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1312</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="224">
         <PDBx:U11>0.1542</PDBx:U11>
         <PDBx:U12>-0.0029</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1346</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="225">
         <PDBx:U11>0.1483</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.1302</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="226">
         <PDBx:U11>0.1950</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.1686</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="227">
         <PDBx:U11>0.2296</PDBx:U11>
         <PDBx:U12>-0.0050</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.2017</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.1890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="228">
         <PDBx:U11>0.2576</PDBx:U11>
         <PDBx:U12>-0.0017</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.2289</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.2158</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="229">
         <PDBx:U11>0.3045</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.2772</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.2640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="230">
         <PDBx:U11>0.3215</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.2890</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.2759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="231">
         <PDBx:U11>0.1524</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.1312</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="232">
         <PDBx:U11>0.1607</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.1390</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1252</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="233">
         <PDBx:U11>0.1697</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.1434</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="234">
         <PDBx:U11>0.1825</PDBx:U11>
         <PDBx:U12>-0.0031</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.1512</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="235">
         <PDBx:U11>0.1773</PDBx:U11>
         <PDBx:U12>0.0032</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.1539</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.1389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="236">
         <PDBx:U11>0.1740</PDBx:U11>
         <PDBx:U12>0.0048</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.1528</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1373</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="237">
         <PDBx:U11>0.1662</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1440</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1296</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="238">
         <PDBx:U11>0.1668</PDBx:U11>
         <PDBx:U12>-0.0033</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1416</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1287</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="239">
         <PDBx:U11>0.1798</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1500</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1377</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="240">
         <PDBx:U11>0.1889</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1520</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="241">
         <PDBx:U11>0.1901</PDBx:U11>
         <PDBx:U12>-0.0014</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.1525</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="242">
         <PDBx:U11>0.1743</PDBx:U11>
         <PDBx:U12>-0.0061</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.1463</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.1341</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="243">
         <PDBx:U11>0.1931</PDBx:U11>
         <PDBx:U12>-0.0081</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.1601</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="244">
         <PDBx:U11>0.1737</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.1515</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.1395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="245">
         <PDBx:U11>0.2106</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.1681</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1560</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="246">
         <PDBx:U11>0.2271</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1761</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1639</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U22>0.1802</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.1944</PDBx:U22>
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         <PDBx:U33>0.1827</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0042</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0033</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="270">
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         <PDBx:U13>0.0116</PDBx:U13>
         <PDBx:U22>0.2182</PDBx:U22>
         <PDBx:U23>-0.0062</PDBx:U23>
         <PDBx:U33>0.2056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0130</PDBx:U13>
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         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.1889</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0149</PDBx:U13>
         <PDBx:U22>0.2280</PDBx:U22>
         <PDBx:U23>-0.0071</PDBx:U23>
         <PDBx:U33>0.2149</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="273">
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         <PDBx:U13>0.0105</PDBx:U13>
         <PDBx:U22>0.2346</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.2222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="274">
         <PDBx:U11>0.3036</PDBx:U11>
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         <PDBx:U13>0.0095</PDBx:U13>
         <PDBx:U22>0.2565</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.2439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="275">
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         <PDBx:U13>0.0083</PDBx:U13>
         <PDBx:U22>0.2670</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.2547</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="276">
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         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.2758</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.2621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.1853</PDBx:U22>
         <PDBx:U23>-0.0060</PDBx:U23>
         <PDBx:U33>0.1732</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="278">
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         <PDBx:U12>-0.0233</PDBx:U12>
         <PDBx:U13>0.0132</PDBx:U13>
         <PDBx:U22>0.1831</PDBx:U22>
         <PDBx:U23>-0.0062</PDBx:U23>
         <PDBx:U33>0.1711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="279">
         <PDBx:U11>0.2528</PDBx:U11>
         <PDBx:U12>-0.0213</PDBx:U12>
         <PDBx:U13>0.0125</PDBx:U13>
         <PDBx:U22>0.1777</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.1661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="280">
         <PDBx:U11>0.2722</PDBx:U11>
         <PDBx:U12>-0.0229</PDBx:U12>
         <PDBx:U13>0.0140</PDBx:U13>
         <PDBx:U22>0.1944</PDBx:U22>
         <PDBx:U23>-0.0062</PDBx:U23>
         <PDBx:U33>0.1828</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="281">
         <PDBx:U11>0.2314</PDBx:U11>
         <PDBx:U12>-0.0182</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.1631</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.1517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="282">
         <PDBx:U11>0.2194</PDBx:U11>
         <PDBx:U12>-0.0167</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.1563</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="283">
         <PDBx:U11>0.2152</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.1478</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1365</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="284">
         <PDBx:U11>0.2099</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.1466</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1349</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="285">
         <PDBx:U11>0.2191</PDBx:U11>
         <PDBx:U12>-0.0155</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.1652</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.1539</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="286">
         <PDBx:U11>0.2285</PDBx:U11>
         <PDBx:U12>-0.0181</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.1796</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.1681</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="287">
         <PDBx:U11>0.2241</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>0.0095</PDBx:U13>
         <PDBx:U22>0.1834</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.1719</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="288">
         <PDBx:U11>0.2365</PDBx:U11>
         <PDBx:U12>-0.0209</PDBx:U12>
         <PDBx:U13>0.0135</PDBx:U13>
         <PDBx:U22>0.1888</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.1769</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="289">
         <PDBx:U11>0.2082</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>0.0074</PDBx:U13>
         <PDBx:U22>0.1324</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1211</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="290">
         <PDBx:U11>0.2169</PDBx:U11>
         <PDBx:U12>-0.0115</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.1359</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1241</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="291">
         <PDBx:U11>0.2086</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.1313</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="292">
         <PDBx:U11>0.2291</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1496</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1365</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="293">
         <PDBx:U11>0.2356</PDBx:U11>
         <PDBx:U12>-0.0128</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1432</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="294">
         <PDBx:U11>0.2633</PDBx:U11>
         <PDBx:U12>-0.0144</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.1657</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.1543</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="295">
         <PDBx:U11>0.2802</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.1821</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="296">
         <PDBx:U11>0.2806</PDBx:U11>
         <PDBx:U12>-0.0186</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.1789</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.1676</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="297">
         <PDBx:U11>0.2949</PDBx:U11>
         <PDBx:U12>-0.0143</PDBx:U12>
         <PDBx:U13>0.0075</PDBx:U13>
         <PDBx:U22>0.1914</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1800</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="298">
         <PDBx:U11>0.2925</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.1869</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.1756</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="299">
         <PDBx:U11>0.1846</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.1131</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.1012</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="300">
         <PDBx:U11>0.1798</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.1122</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.0999</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="301">
         <PDBx:U11>0.1653</PDBx:U11>
         <PDBx:U12>-0.0094</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.1069</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.0942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="302">
         <PDBx:U11>0.1659</PDBx:U11>
         <PDBx:U12>-0.0089</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1107</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0974</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="303">
         <PDBx:U11>0.1752</PDBx:U11>
         <PDBx:U12>-0.0134</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1067</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.0950</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="304">
         <PDBx:U11>0.1776</PDBx:U11>
         <PDBx:U12>-0.0154</PDBx:U12>
         <PDBx:U13>0.0089</PDBx:U13>
         <PDBx:U22>0.1136</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="305">
         <PDBx:U11>0.1810</PDBx:U11>
         <PDBx:U12>-0.0154</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.1201</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.1091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="306">
         <PDBx:U11>0.1913</PDBx:U11>
         <PDBx:U12>-0.0170</PDBx:U12>
         <PDBx:U13>0.0112</PDBx:U13>
         <PDBx:U22>0.1274</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1167</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="307">
         <PDBx:U11>0.1624</PDBx:U11>
         <PDBx:U12>-0.0089</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.1074</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.0949</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="308">
         <PDBx:U11>0.1523</PDBx:U11>
         <PDBx:U12>-0.0080</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1054</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.0927</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="309">
         <PDBx:U11>0.1540</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.1102</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="310">
         <PDBx:U11>0.1513</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.1124</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="311">
         <PDBx:U11>0.1565</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.1114</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.0990</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="312">
         <PDBx:U11>0.1500</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.1127</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1002</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="313">
         <PDBx:U11>0.1454</PDBx:U11>
         <PDBx:U12>-0.0089</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.1116</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.0998</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="314">
         <PDBx:U11>0.1532</PDBx:U11>
         <PDBx:U12>-0.0050</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.1195</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="315">
         <PDBx:U11>0.1517</PDBx:U11>
         <PDBx:U12>-0.0083</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1240</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.1121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="316">
         <PDBx:U11>0.1548</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.1274</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1140</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="317">
         <PDBx:U11>0.1486</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.1236</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="318">
         <PDBx:U11>0.1488</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.1291</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1165</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="319">
         <PDBx:U11>0.1663</PDBx:U11>
         <PDBx:U12>-0.0036</PDBx:U12>
         <PDBx:U13>-0.0034</PDBx:U13>
         <PDBx:U22>0.1199</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.1047</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="320">
         <PDBx:U11>0.1727</PDBx:U11>
         <PDBx:U12>-0.0012</PDBx:U12>
         <PDBx:U13>-0.0063</PDBx:U13>
         <PDBx:U22>0.1305</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="321">
         <PDBx:U11>0.1794</PDBx:U11>
         <PDBx:U12>-0.0017</PDBx:U12>
         <PDBx:U13>-0.0078</PDBx:U13>
         <PDBx:U22>0.1361</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.1176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="322">
         <PDBx:U11>0.1925</PDBx:U11>
         <PDBx:U12>-0.0007</PDBx:U12>
         <PDBx:U13>-0.0101</PDBx:U13>
         <PDBx:U22>0.1540</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.1335</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="323">
         <PDBx:U11>0.1839</PDBx:U11>
         <PDBx:U12>0.0019</PDBx:U12>
         <PDBx:U13>-0.0079</PDBx:U13>
         <PDBx:U22>0.1405</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.1222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="324">
         <PDBx:U11>0.1913</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.1500</PDBx:U22>
         <PDBx:U23>-0.0010</PDBx:U23>
         <PDBx:U33>0.1325</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="325">
         <PDBx:U11>0.1917</PDBx:U11>
         <PDBx:U12>0.0028</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.1580</PDBx:U22>
         <PDBx:U23>-0.0010</PDBx:U23>
         <PDBx:U33>0.1399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="326">
         <PDBx:U11>0.1975</PDBx:U11>
         <PDBx:U12>0.0021</PDBx:U12>
         <PDBx:U13>-0.0051</PDBx:U13>
         <PDBx:U22>0.1513</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1351</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="327">
         <PDBx:U11>0.1900</PDBx:U11>
         <PDBx:U12>0.0030</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>0.1560</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="328">
         <PDBx:U11>0.2018</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>-0.0046</PDBx:U13>
         <PDBx:U22>0.1605</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.1445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="329">
         <PDBx:U11>0.1755</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>-0.0064</PDBx:U13>
         <PDBx:U22>0.1261</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="330">
         <PDBx:U11>0.1851</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>-0.0074</PDBx:U13>
         <PDBx:U22>0.1342</PDBx:U22>
         <PDBx:U23>-0.0010</PDBx:U23>
         <PDBx:U33>0.1160</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="331">
         <PDBx:U11>0.1931</PDBx:U11>
         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>-0.0061</PDBx:U13>
         <PDBx:U22>0.1462</PDBx:U22>
         <PDBx:U23>-0.0013</PDBx:U23>
         <PDBx:U33>0.1285</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="332">
         <PDBx:U11>0.2252</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>-0.0074</PDBx:U13>
         <PDBx:U22>0.1792</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.1603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="333">
         <PDBx:U11>0.1920</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>-0.0062</PDBx:U13>
         <PDBx:U22>0.1320</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1147</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="334">
         <PDBx:U11>0.1950</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>-0.0074</PDBx:U13>
         <PDBx:U22>0.1294</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.1117</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="335">
         <PDBx:U11>0.2124</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>-0.0107</PDBx:U13>
         <PDBx:U22>0.1468</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.1269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="336">
         <PDBx:U11>0.1990</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>-0.0053</PDBx:U13>
         <PDBx:U22>0.1293</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1130</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="337">
         <PDBx:U11>0.1746</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.1298</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.1139</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="338">
         <PDBx:U11>0.1752</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.1336</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.1183</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="339">
         <PDBx:U11>0.1648</PDBx:U11>
         <PDBx:U12>-0.0083</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.1303</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="340">
         <PDBx:U11>0.1867</PDBx:U11>
         <PDBx:U12>-0.0092</PDBx:U12>
         <PDBx:U13>-0.0034</PDBx:U13>
         <PDBx:U22>0.1544</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1379</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="341">
         <PDBx:U11>0.1783</PDBx:U11>
         <PDBx:U12>-0.0103</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1349</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="342">
         <PDBx:U11>0.1882</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1376</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1248</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="343">
         <PDBx:U11>0.1779</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1384</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1258</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="344">
         <PDBx:U11>0.1967</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.1445</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1330</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="345">
         <PDBx:U11>0.1636</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1320</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1158</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="346">
         <PDBx:U11>0.1635</PDBx:U11>
         <PDBx:U12>-0.0061</PDBx:U12>
         <PDBx:U13>-0.0043</PDBx:U13>
         <PDBx:U22>0.1382</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.1214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="347">
         <PDBx:U11>0.1773</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.1547</PDBx:U22>
         <PDBx:U23>-0.0013</PDBx:U23>
         <PDBx:U33>0.1355</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="348">
         <PDBx:U11>0.2012</PDBx:U11>
         <PDBx:U12>-0.0025</PDBx:U12>
         <PDBx:U13>-0.0074</PDBx:U13>
         <PDBx:U22>0.1773</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1579</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="349">
         <PDBx:U11>0.1522</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>-0.0027</PDBx:U13>
         <PDBx:U22>0.1282</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.1128</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="350">
         <PDBx:U11>0.1517</PDBx:U11>
         <PDBx:U12>-0.0074</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.1262</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1126</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="351">
         <PDBx:U11>0.1464</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>-0.0034</PDBx:U13>
         <PDBx:U22>0.1282</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="352">
         <PDBx:U11>0.1569</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.1331</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1196</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="353">
         <PDBx:U11>0.1887</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>-0.0085</PDBx:U13>
         <PDBx:U22>0.1699</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.1487</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="354">
         <PDBx:U11>0.2133</PDBx:U11>
         <PDBx:U12>-0.0032</PDBx:U12>
         <PDBx:U13>-0.0111</PDBx:U13>
         <PDBx:U22>0.1986</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.1745</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="355">
         <PDBx:U11>0.1960</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>-0.0113</PDBx:U13>
         <PDBx:U22>0.1878</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.1626</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="356">
         <PDBx:U11>0.1955</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>-0.0129</PDBx:U13>
         <PDBx:U22>0.1910</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.1634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="357">
         <PDBx:U11>0.2711</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>-0.0130</PDBx:U13>
         <PDBx:U22>0.2576</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.2311</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="358">
         <PDBx:U11>0.3402</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>-0.0133</PDBx:U13>
         <PDBx:U22>0.3197</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.2937</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="359">
         <PDBx:U11>0.3905</PDBx:U11>
         <PDBx:U12>-0.0031</PDBx:U12>
         <PDBx:U13>-0.0138</PDBx:U13>
         <PDBx:U22>0.3655</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.3399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="360">
         <PDBx:U11>0.4546</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>-0.0150</PDBx:U13>
         <PDBx:U22>0.4234</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.3972</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.4942</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="378">
         <PDBx:U11>0.1545</PDBx:U11>
         <PDBx:U12>0.0016</PDBx:U12>
         <PDBx:U13>-0.0083</PDBx:U13>
         <PDBx:U22>0.1461</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.1242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="379">
         <PDBx:U11>0.1271</PDBx:U11>
         <PDBx:U12>-0.0017</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.1234</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1061</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="380">
         <PDBx:U11>0.1203</PDBx:U11>
         <PDBx:U12>-0.0015</PDBx:U12>
         <PDBx:U13>-0.0033</PDBx:U13>
         <PDBx:U22>0.1198</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1023</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="381">
         <PDBx:U11>0.1167</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>-0.0022</PDBx:U13>
         <PDBx:U22>0.1142</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="382">
         <PDBx:U11>0.1278</PDBx:U11>
         <PDBx:U12>-0.0032</PDBx:U12>
         <PDBx:U13>-0.0015</PDBx:U13>
         <PDBx:U22>0.1230</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="383">
         <PDBx:U11>0.1222</PDBx:U11>
         <PDBx:U12>-0.0029</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.1247</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.1065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="384">
         <PDBx:U11>0.1228</PDBx:U11>
         <PDBx:U12>-0.0031</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.1283</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.1096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="385">
         <PDBx:U11>0.1367</PDBx:U11>
         <PDBx:U12>-0.0010</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1455</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.1247</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="386">
         <PDBx:U11>0.1414</PDBx:U11>
         <PDBx:U12>-0.0007</PDBx:U12>
         <PDBx:U13>-0.0050</PDBx:U13>
         <PDBx:U22>0.1536</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1299</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="387">
         <PDBx:U11>0.1147</PDBx:U11>
         <PDBx:U12>-0.0016</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.1133</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="388">
         <PDBx:U11>0.1152</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1121</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0976</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="389">
         <PDBx:U11>0.1081</PDBx:U11>
         <PDBx:U12>-0.0019</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1070</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="390">
         <PDBx:U11>0.1089</PDBx:U11>
         <PDBx:U12>-0.0009</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.1101</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0939</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="391">
         <PDBx:U11>0.1290</PDBx:U11>
         <PDBx:U12>-0.0019</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.1218</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1077</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="392">
         <PDBx:U11>0.1416</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1336</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1186</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="393">
         <PDBx:U11>0.1539</PDBx:U11>
         <PDBx:U12>0.0018</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.1467</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.1305</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0031</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.1434</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1300</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.1282</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1108</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0025</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.1115</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="411">
         <PDBx:U11>0.1205</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.1288</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1078</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="412">
         <PDBx:U11>0.1218</PDBx:U11>
         <PDBx:U12>0.0043</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1341</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="413">
         <PDBx:U11>0.1415</PDBx:U11>
         <PDBx:U12>0.0045</PDBx:U12>
         <PDBx:U13>-0.0027</PDBx:U13>
         <PDBx:U22>0.1457</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1252</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="414">
         <PDBx:U11>0.1697</PDBx:U11>
         <PDBx:U12>0.0058</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.1688</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="415">
         <PDBx:U11>0.1489</PDBx:U11>
         <PDBx:U12>0.0055</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1585</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1352</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="416">
         <PDBx:U11>0.1123</PDBx:U11>
         <PDBx:U12>0.0010</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1200</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="417">
         <PDBx:U11>0.1128</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.1230</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="418">
         <PDBx:U11>0.1114</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.1216</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="419">
         <PDBx:U11>0.1090</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1225</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.0999</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="420">
         <PDBx:U11>0.1090</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>-0.0011</PDBx:U13>
         <PDBx:U22>0.1172</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0986</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="421">
         <PDBx:U11>0.1142</PDBx:U11>
         <PDBx:U12>-0.0036</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.1235</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="422">
         <PDBx:U11>0.1109</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.1190</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1006</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="423">
         <PDBx:U11>0.1149</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.1211</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1019</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="424">
         <PDBx:U11>0.1314</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.1366</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1171</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="425">
         <PDBx:U11>0.1316</PDBx:U11>
         <PDBx:U12>0.0039</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.1392</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="426">
         <PDBx:U11>0.1271</PDBx:U11>
         <PDBx:U12>0.0041</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1369</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1140</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="427">
         <PDBx:U11>0.1513</PDBx:U11>
         <PDBx:U12>0.0013</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.1513</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1336</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="428">
         <PDBx:U11>0.1906</PDBx:U11>
         <PDBx:U12>0.0018</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.1883</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1704</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="429">
         <PDBx:U11>0.2454</PDBx:U11>
         <PDBx:U12>0.0010</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.2378</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.2214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="430">
         <PDBx:U11>0.2907</PDBx:U11>
         <PDBx:U12>0.0012</PDBx:U12>
         <PDBx:U13>0.0024</PDBx:U13>
         <PDBx:U22>0.2798</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.2634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="431">
         <PDBx:U11>0.3321</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.3231</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.3064</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="432">
         <PDBx:U11>0.1365</PDBx:U11>
         <PDBx:U12>0.0059</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1441</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="433">
         <PDBx:U11>0.1518</PDBx:U11>
         <PDBx:U12>0.0090</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.1625</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="434">
         <PDBx:U11>0.1396</PDBx:U11>
         <PDBx:U12>0.0082</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.1577</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="435">
         <PDBx:U11>0.1439</PDBx:U11>
         <PDBx:U12>0.0095</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.1657</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1362</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="436">
         <PDBx:U11>0.1844</PDBx:U11>
         <PDBx:U12>0.0113</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1933</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1686</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="437">
         <PDBx:U11>0.2469</PDBx:U11>
         <PDBx:U12>0.0152</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.2594</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.2319</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="438">
         <PDBx:U11>0.3255</PDBx:U11>
         <PDBx:U12>0.0174</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.3365</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.3086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="439">
         <PDBx:U11>0.3855</PDBx:U11>
         <PDBx:U12>0.0154</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.4005</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.3718</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="440">
         <PDBx:U11>0.4367</PDBx:U11>
         <PDBx:U12>0.0161</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.4590</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.4270</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="441">
         <PDBx:U11>0.4901</PDBx:U11>
         <PDBx:U12>0.0191</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.5177</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.4826</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="442">
         <PDBx:U11>0.4467</PDBx:U11>
         <PDBx:U12>0.0137</PDBx:U12>
         <PDBx:U13>-0.0041</PDBx:U13>
         <PDBx:U22>0.4712</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.4388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="443">
         <PDBx:U11>0.1260</PDBx:U11>
         <PDBx:U12>0.0060</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1462</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1187</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="444">
         <PDBx:U11>0.1321</PDBx:U11>
         <PDBx:U12>0.0045</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1587</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1285</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="445">
         <PDBx:U11>0.1376</PDBx:U11>
         <PDBx:U12>0.0025</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.1650</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="446">
         <PDBx:U11>0.1511</PDBx:U11>
         <PDBx:U12>0.0023</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1838</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.1503</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="447">
         <PDBx:U11>0.1278</PDBx:U11>
         <PDBx:U12>0.0023</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1549</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1249</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="448">
         <PDBx:U11>0.1331</PDBx:U11>
         <PDBx:U12>0.0043</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.1605</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="449">
         <PDBx:U11>0.1383</PDBx:U11>
         <PDBx:U12>0.0021</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.1653</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1349</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="450">
         <PDBx:U11>0.1438</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1766</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="451">
         <PDBx:U11>0.1602</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.1919</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1584</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="452">
         <PDBx:U11>0.1351</PDBx:U11>
         <PDBx:U12>0.0011</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.1571</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.1294</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="453">
         <PDBx:U11>0.1434</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.1649</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1370</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="454">
         <PDBx:U11>0.1403</PDBx:U11>
         <PDBx:U12>0.0014</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.1623</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1332</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="455">
         <PDBx:U11>0.1493</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.1748</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="456">
         <PDBx:U11>0.1490</PDBx:U11>
         <PDBx:U12>-0.0019</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.1646</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="457">
         <PDBx:U11>0.1703</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.1844</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="458">
         <PDBx:U11>0.1900</PDBx:U11>
         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.2066</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="459">
         <PDBx:U11>0.2067</PDBx:U11>
         <PDBx:U12>-0.0079</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.2195</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1953</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="476">
         <PDBx:U11>0.2913</PDBx:U11>
         <PDBx:U12>0.0189</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.3203</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.2845</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="477">
         <PDBx:U11>0.1653</PDBx:U11>
         <PDBx:U12>0.0040</PDBx:U12>
         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.2072</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.1678</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="478">
         <PDBx:U11>0.1791</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.2260</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.1840</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="479">
         <PDBx:U11>0.1714</PDBx:U11>
         <PDBx:U12>-0.0009</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.2237</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.1794</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="480">
         <PDBx:U11>0.1822</PDBx:U11>
         <PDBx:U12>-0.0033</PDBx:U12>
         <PDBx:U13>0.0062</PDBx:U13>
         <PDBx:U22>0.2413</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.1931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="481">
         <PDBx:U11>0.2113</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.2637</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.2182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="482">
         <PDBx:U11>0.2618</PDBx:U11>
         <PDBx:U12>0.0007</PDBx:U12>
         <PDBx:U13>0.0118</PDBx:U13>
         <PDBx:U22>0.3077</PDBx:U22>
         <PDBx:U23>-0.0060</PDBx:U23>
         <PDBx:U33>0.2645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="483">
         <PDBx:U11>0.3222</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>0.0146</PDBx:U13>
         <PDBx:U22>0.3723</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.3260</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="484">
         <PDBx:U11>0.4055</PDBx:U11>
         <PDBx:U12>0.0037</PDBx:U12>
         <PDBx:U13>0.0162</PDBx:U13>
         <PDBx:U22>0.4595</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.4109</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="485">
         <PDBx:U11>0.4283</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>0.0190</PDBx:U13>
         <PDBx:U22>0.4865</PDBx:U22>
         <PDBx:U23>-0.0077</PDBx:U23>
         <PDBx:U33>0.4348</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="486">
         <PDBx:U11>0.4408</PDBx:U11>
         <PDBx:U12>-0.0010</PDBx:U12>
         <PDBx:U13>0.0205</PDBx:U13>
         <PDBx:U22>0.4995</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.4467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="487">
         <PDBx:U11>0.4572</PDBx:U11>
         <PDBx:U12>0.0079</PDBx:U12>
         <PDBx:U13>0.0206</PDBx:U13>
         <PDBx:U22>0.5187</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.4651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="488">
         <PDBx:U11>0.1606</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.2095</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.1674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="489">
         <PDBx:U11>0.1616</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.2142</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="490">
         <PDBx:U11>0.1555</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.2066</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.1630</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="491">
         <PDBx:U11>0.1734</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.2299</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.1830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="492">
         <PDBx:U11>0.1751</PDBx:U11>
         <PDBx:U12>0.0020</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.2232</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1819</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="493">
         <PDBx:U11>0.2032</PDBx:U11>
         <PDBx:U12>0.0028</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.2561</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.2121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="494">
         <PDBx:U11>0.2219</PDBx:U11>
         <PDBx:U12>0.0057</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.2716</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.2290</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="495">
         <PDBx:U11>0.2631</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.3232</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.2752</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="496">
         <PDBx:U11>0.1451</PDBx:U11>
         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.1886</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="497">
         <PDBx:U11>0.1452</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.1860</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="498">
         <PDBx:U11>0.1652</PDBx:U11>
         <PDBx:U12>-0.0139</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.2092</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1670</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="499">
         <PDBx:U11>0.1916</PDBx:U11>
         <PDBx:U12>-0.0136</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.2349</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.1928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="500">
         <PDBx:U11>0.1379</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.1701</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1355</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="501">
         <PDBx:U11>0.1259</PDBx:U11>
         <PDBx:U12>-0.0085</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.1545</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1227</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="502">
         <PDBx:U11>0.1209</PDBx:U11>
         <PDBx:U12>-0.0090</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.1500</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1179</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="503">
         <PDBx:U11>0.1195</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.1443</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="504">
         <PDBx:U11>0.1224</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1482</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1185</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="505">
         <PDBx:U11>0.1170</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1388</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1118</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="506">
         <PDBx:U11>0.1162</PDBx:U11>
         <PDBx:U12>-0.0051</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.1384</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="507">
         <PDBx:U11>0.1218</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.1408</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1157</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="508">
         <PDBx:U11>0.1661</PDBx:U11>
         <PDBx:U12>-0.0173</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.2131</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.1682</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="509">
         <PDBx:U11>0.1856</PDBx:U11>
         <PDBx:U12>-0.0211</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.2355</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.1874</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="510">
         <PDBx:U11>0.1868</PDBx:U11>
         <PDBx:U12>-0.0244</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.2285</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.1827</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="511">
         <PDBx:U11>0.2055</PDBx:U11>
         <PDBx:U12>-0.0273</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.2470</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.1995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="512">
         <PDBx:U11>0.2002</PDBx:U11>
         <PDBx:U12>-0.0234</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.2591</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.2057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="513">
         <PDBx:U11>0.2177</PDBx:U11>
         <PDBx:U12>-0.0197</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.2858</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.2292</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="514">
         <PDBx:U11>0.2420</PDBx:U11>
         <PDBx:U12>-0.0223</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.3210</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.2580</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="515">
         <PDBx:U11>0.2869</PDBx:U11>
         <PDBx:U12>-0.0264</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.3687</PDBx:U22>
         <PDBx:U23>-0.0078</PDBx:U23>
         <PDBx:U33>0.3027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="516">
         <PDBx:U11>0.3189</PDBx:U11>
         <PDBx:U12>-0.0321</PDBx:U12>
         <PDBx:U13>0.0067</PDBx:U13>
         <PDBx:U22>0.4030</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.3335</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="517">
         <PDBx:U11>0.3585</PDBx:U11>
         <PDBx:U12>-0.0345</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.4428</PDBx:U22>
         <PDBx:U23>-0.0081</PDBx:U23>
         <PDBx:U33>0.3722</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="518">
         <PDBx:U11>0.3366</PDBx:U11>
         <PDBx:U12>-0.0357</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.4225</PDBx:U22>
         <PDBx:U23>-0.0090</PDBx:U23>
         <PDBx:U33>0.3504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="519">
         <PDBx:U11>0.1832</PDBx:U11>
         <PDBx:U12>-0.0238</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.2179</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.1757</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="520">
         <PDBx:U11>0.1855</PDBx:U11>
         <PDBx:U12>-0.0261</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.2119</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.1721</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="521">
         <PDBx:U11>0.1638</PDBx:U11>
         <PDBx:U12>-0.0233</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.1836</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.1484</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="522">
         <PDBx:U11>0.1519</PDBx:U11>
         <PDBx:U12>-0.0204</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1734</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="523">
         <PDBx:U11>0.2178</PDBx:U11>
         <PDBx:U12>-0.0306</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.2440</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.2016</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="524">
         <PDBx:U11>0.2425</PDBx:U11>
         <PDBx:U12>-0.0306</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.2717</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.2281</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="525">
         <PDBx:U11>0.2259</PDBx:U11>
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         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="542">
         <PDBx:U11>0.1361</PDBx:U11>
         <PDBx:U12>-0.0190</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1587</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="543">
         <PDBx:U11>0.1230</PDBx:U11>
         <PDBx:U12>-0.0155</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1426</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1125</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="544">
         <PDBx:U11>0.1352</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.1540</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1252</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="545">
         <PDBx:U11>0.1456</PDBx:U11>
         <PDBx:U12>-0.0190</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.1762</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.1388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="546">
         <PDBx:U11>0.1619</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>-0.0023</PDBx:U13>
         <PDBx:U22>0.1973</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.1586</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="547">
         <PDBx:U11>0.1696</PDBx:U11>
         <PDBx:U12>-0.0155</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.2135</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="548">
         <PDBx:U11>0.2167</PDBx:U11>
         <PDBx:U12>-0.0126</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.2640</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.2204</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="549">
         <PDBx:U11>0.1771</PDBx:U11>
         <PDBx:U12>-0.0173</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.2240</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="550">
         <PDBx:U11>0.1186</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.1361</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.1075</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="551">
         <PDBx:U11>0.1125</PDBx:U11>
         <PDBx:U12>-0.0122</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.1270</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1014</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="552">
         <PDBx:U11>0.1085</PDBx:U11>
         <PDBx:U12>-0.0119</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1183</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.0953</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="553">
         <PDBx:U11>0.1031</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1123</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.0908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="554">
         <PDBx:U11>0.1143</PDBx:U11>
         <PDBx:U12>-0.0123</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1270</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.1021</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="555">
         <PDBx:U11>0.1094</PDBx:U11>
         <PDBx:U12>-0.0104</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.1184</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.0965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="556">
         <PDBx:U11>0.1150</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.1251</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1037</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="557">
         <PDBx:U11>0.1185</PDBx:U11>
         <PDBx:U12>-0.0106</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1231</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="558">
         <PDBx:U11>0.1192</PDBx:U11>
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         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.1263</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1071</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="559">
         <PDBx:U11>0.1247</PDBx:U11>
         <PDBx:U12>-0.0090</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.1271</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="560">
         <PDBx:U11>0.1191</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.1229</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1052</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="561">
         <PDBx:U11>0.1081</PDBx:U11>
         <PDBx:U12>-0.0135</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.1142</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.0916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="562">
         <PDBx:U11>0.1091</PDBx:U11>
         <PDBx:U12>-0.0128</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1107</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.0903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="563">
         <PDBx:U11>0.1110</PDBx:U11>
         <PDBx:U12>-0.0127</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.1132</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.0927</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="564">
         <PDBx:U11>0.1089</PDBx:U11>
         <PDBx:U12>-0.0112</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.1091</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0905</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="565">
         <PDBx:U11>0.1177</PDBx:U11>
         <PDBx:U12>-0.0143</PDBx:U12>
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         <PDBx:U22>0.1145</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.0944</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="566">
         <PDBx:U11>0.1133</PDBx:U11>
         <PDBx:U12>-0.0144</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.1183</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.0953</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="567">
         <PDBx:U11>0.1200</PDBx:U11>
         <PDBx:U12>-0.0144</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.1252</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="568">
         <PDBx:U11>0.1125</PDBx:U11>
         <PDBx:U12>-0.0119</PDBx:U12>
         <PDBx:U13>-0.0028</PDBx:U13>
         <PDBx:U22>0.1192</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0969</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="569">
         <PDBx:U11>0.1224</PDBx:U11>
         <PDBx:U12>-0.0112</PDBx:U12>
         <PDBx:U13>-0.0030</PDBx:U13>
         <PDBx:U22>0.1267</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="570">
         <PDBx:U11>0.1229</PDBx:U11>
         <PDBx:U12>-0.0168</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.1315</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1047</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="571">
         <PDBx:U11>0.1088</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>-0.0028</PDBx:U13>
         <PDBx:U22>0.1187</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0959</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="572">
         <PDBx:U11>0.1122</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>-0.0030</PDBx:U13>
         <PDBx:U22>0.1223</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1005</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="573">
         <PDBx:U11>0.1023</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.1088</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0899</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="574">
         <PDBx:U11>0.1078</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>-0.0023</PDBx:U13>
         <PDBx:U22>0.1126</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0948</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="575">
         <PDBx:U11>0.1168</PDBx:U11>
         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>-0.0030</PDBx:U13>
         <PDBx:U22>0.1303</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="576">
         <PDBx:U11>0.1296</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.1475</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="577">
         <PDBx:U11>0.1561</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.1746</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.1475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="578">
         <PDBx:U11>0.1361</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1571</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1299</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="579">
         <PDBx:U11>0.0988</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.1041</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="580">
         <PDBx:U11>0.0997</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>-0.0015</PDBx:U13>
         <PDBx:U22>0.1028</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="581">
         <PDBx:U11>0.0993</PDBx:U11>
         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1000</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0852</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="582">
         <PDBx:U11>0.1030</PDBx:U11>
         <PDBx:U12>-0.0061</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.1029</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0891</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="583">
         <PDBx:U11>0.1094</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1118</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="584">
         <PDBx:U11>0.1194</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1205</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1067</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="585">
         <PDBx:U11>0.1107</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1148</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="586">
         <PDBx:U11>0.1027</PDBx:U11>
         <PDBx:U12>-0.0080</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1019</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="587">
         <PDBx:U11>0.1102</PDBx:U11>
         <PDBx:U12>-0.0081</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.1063</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0917</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="588">
         <PDBx:U11>0.1111</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1072</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0923</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="589">
         <PDBx:U11>0.1205</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.1146</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1008</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="590">
         <PDBx:U11>0.1170</PDBx:U11>
         <PDBx:U12>-0.0095</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1105</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0952</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="591">
         <PDBx:U11>0.1253</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.1169</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="592">
         <PDBx:U11>0.1294</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.1179</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="593">
         <PDBx:U11>0.1249</PDBx:U11>
         <PDBx:U12>-0.0099</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1100</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0954</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="594">
         <PDBx:U11>0.1252</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1076</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0921</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="595">
         <PDBx:U11>0.1327</PDBx:U11>
         <PDBx:U12>-0.0146</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1163</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="596">
         <PDBx:U11>0.1434</PDBx:U11>
         <PDBx:U12>-0.0106</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.1218</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1072</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="597">
         <PDBx:U11>0.1085</PDBx:U11>
         <PDBx:U12>-0.0086</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.1070</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="598">
         <PDBx:U11>0.1126</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>-0.0022</PDBx:U13>
         <PDBx:U22>0.1107</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="599">
         <PDBx:U11>0.1097</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.1068</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="600">
         <PDBx:U11>0.1129</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>-0.0011</PDBx:U13>
         <PDBx:U22>0.1075</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0929</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="601">
         <PDBx:U11>0.1157</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.1173</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0981</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="602">
         <PDBx:U11>0.1267</PDBx:U11>
         <PDBx:U12>-0.0074</PDBx:U12>
         <PDBx:U13>-0.0044</PDBx:U13>
         <PDBx:U22>0.1281</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1082</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="603">
         <PDBx:U11>0.1390</PDBx:U11>
         <PDBx:U12>-0.0085</PDBx:U12>
         <PDBx:U13>-0.0046</PDBx:U13>
         <PDBx:U22>0.1371</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1172</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="604">
         <PDBx:U11>0.1321</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>-0.0057</PDBx:U13>
         <PDBx:U22>0.1380</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="605">
         <PDBx:U11>0.1083</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.1071</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0922</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="606">
         <PDBx:U11>0.1120</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.1098</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="607">
         <PDBx:U11>0.1070</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1033</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.0908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="608">
         <PDBx:U11>0.1221</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1168</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1048</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="609">
         <PDBx:U11>0.1261</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.1258</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="610">
         <PDBx:U11>0.1284</PDBx:U11>
         <PDBx:U12>-0.0051</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.1272</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="611">
         <PDBx:U11>0.1376</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.1378</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1249</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="612">
         <PDBx:U11>0.1380</PDBx:U11>
         <PDBx:U12>-0.0051</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.1395</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1271</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="613">
         <PDBx:U11>0.1111</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1077</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.0955</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="614">
         <PDBx:U11>0.1090</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.1046</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.0934</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="615">
         <PDBx:U11>0.1073</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.0999</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.0887</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="616">
         <PDBx:U11>0.1146</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.1063</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.0956</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="617">
         <PDBx:U11>0.1155</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.1114</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1004</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="618">
         <PDBx:U11>0.1226</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.1210</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="619">
         <PDBx:U11>0.1325</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1330</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1219</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="620">
         <PDBx:U11>0.1354</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.1335</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1221</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="621">
         <PDBx:U11>0.1480</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.1505</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="622">
         <PDBx:U11>0.1409</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.1408</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1293</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="623">
         <PDBx:U11>0.1422</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1442</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1327</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="640">
         <PDBx:U11>0.1260</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.1137</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1035</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="641">
         <PDBx:U11>0.1352</PDBx:U11>
         <PDBx:U12>-0.0086</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.1216</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.1114</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="642">
         <PDBx:U11>0.1319</PDBx:U11>
         <PDBx:U12>-0.0074</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.1254</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1147</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="643">
         <PDBx:U11>0.1596</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.1559</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.1448</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="644">
         <PDBx:U11>0.1242</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.1116</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1016</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="645">
         <PDBx:U11>0.1309</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.1159</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1063</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="646">
         <PDBx:U11>0.1366</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.1167</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1071</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="647">
         <PDBx:U11>0.1611</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>0.0109</PDBx:U13>
         <PDBx:U22>0.1387</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.1295</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="648">
         <PDBx:U11>0.1314</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.1158</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1064</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="649">
         <PDBx:U11>0.1287</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>0.0074</PDBx:U13>
         <PDBx:U22>0.1170</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1075</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="650">
         <PDBx:U11>0.1307</PDBx:U11>
         <PDBx:U12>-0.0036</PDBx:U12>
         <PDBx:U13>0.0080</PDBx:U13>
         <PDBx:U22>0.1232</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="651">
         <PDBx:U11>0.1258</PDBx:U11>
         <PDBx:U12>-0.0039</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.1132</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1036</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="652">
         <PDBx:U11>0.1338</PDBx:U11>
         <PDBx:U12>-0.0025</PDBx:U12>
         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.1296</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1196</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="653">
         <PDBx:U11>0.1314</PDBx:U11>
         <PDBx:U12>-0.0028</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.1214</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1117</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="654">
         <PDBx:U11>0.1311</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.1252</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="655">
         <PDBx:U11>0.1559</PDBx:U11>
         <PDBx:U12>-0.0008</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.1527</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.1427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="656">
         <PDBx:U11>0.1395</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.1181</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.1080</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="657">
         <PDBx:U11>0.1534</PDBx:U11>
         <PDBx:U12>-0.0094</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.1272</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1169</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="658">
         <PDBx:U11>0.1546</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0082</PDBx:U13>
         <PDBx:U22>0.1266</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1165</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="659">
         <PDBx:U11>0.1814</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.1492</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="660">
         <PDBx:U11>0.1604</PDBx:U11>
         <PDBx:U12>-0.0098</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.1341</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1227</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="661">
         <PDBx:U11>0.1915</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.1603</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.1483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="662">
         <PDBx:U11>0.2229</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.1930</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="663">
         <PDBx:U11>0.2804</PDBx:U11>
         <PDBx:U12>-0.0120</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.2455</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.2309</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="664">
         <PDBx:U11>0.3177</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>-0.0030</PDBx:U13>
         <PDBx:U22>0.2854</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.2684</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="665">
         <PDBx:U11>0.1460</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.1204</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="666">
         <PDBx:U11>0.1565</PDBx:U11>
         <PDBx:U12>-0.0112</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.1280</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="667">
         <PDBx:U11>0.1718</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>0.1442</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.1342</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="668">
         <PDBx:U11>0.1891</PDBx:U11>
         <PDBx:U12>-0.0134</PDBx:U12>
         <PDBx:U13>0.0131</PDBx:U13>
         <PDBx:U22>0.1575</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.1475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="669">
         <PDBx:U11>0.1516</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.1244</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1138</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="670">
         <PDBx:U11>0.1525</PDBx:U11>
         <PDBx:U12>-0.0120</PDBx:U12>
         <PDBx:U13>0.0080</PDBx:U13>
         <PDBx:U22>0.1208</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1102</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="671">
         <PDBx:U11>0.1658</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.1284</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="672">
         <PDBx:U11>0.1590</PDBx:U11>
         <PDBx:U12>-0.0133</PDBx:U12>
         <PDBx:U13>0.0095</PDBx:U13>
         <PDBx:U22>0.1285</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="673">
         <PDBx:U11>0.1701</PDBx:U11>
         <PDBx:U12>-0.0132</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.1274</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="674">
         <PDBx:U11>0.1671</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>0.0105</PDBx:U13>
         <PDBx:U22>0.1317</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.1208</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="675">
         <PDBx:U11>0.1651</PDBx:U11>
         <PDBx:U12>-0.0147</PDBx:U12>
         <PDBx:U13>0.0099</PDBx:U13>
         <PDBx:U22>0.1231</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1124</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="676">
         <PDBx:U11>0.1793</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.1314</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.1206</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="677">
         <PDBx:U11>0.1785</PDBx:U11>
         <PDBx:U12>-0.0115</PDBx:U12>
         <PDBx:U13>0.0123</PDBx:U13>
         <PDBx:U22>0.1562</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.1461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="678">
         <PDBx:U11>0.1943</PDBx:U11>
         <PDBx:U12>-0.0124</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>0.1749</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.1642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="679">
         <PDBx:U11>0.2183</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>0.0168</PDBx:U13>
         <PDBx:U22>0.1996</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.1890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="680">
         <PDBx:U11>0.2297</PDBx:U11>
         <PDBx:U12>-0.0098</PDBx:U12>
         <PDBx:U13>0.0161</PDBx:U13>
         <PDBx:U22>0.2113</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.2012</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="681">
         <PDBx:U11>0.1938</PDBx:U11>
         <PDBx:U12>-0.0122</PDBx:U12>
         <PDBx:U13>0.0140</PDBx:U13>
         <PDBx:U22>0.1804</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.1692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="682">
         <PDBx:U11>0.1948</PDBx:U11>
         <PDBx:U12>-0.0130</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.1802</PDBx:U22>
         <PDBx:U23>-0.0060</PDBx:U23>
         <PDBx:U33>0.1689</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="683">
         <PDBx:U11>0.2093</PDBx:U11>
         <PDBx:U12>-0.0149</PDBx:U12>
         <PDBx:U13>0.0133</PDBx:U13>
         <PDBx:U22>0.1925</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.1808</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="684">
         <PDBx:U11>0.1813</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.1674</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.1564</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="685">
         <PDBx:U11>0.2623</PDBx:U11>
         <PDBx:U12>-0.0128</PDBx:U12>
         <PDBx:U13>0.0197</PDBx:U13>
         <PDBx:U22>0.2437</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.2325</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="686">
         <PDBx:U11>0.2885</PDBx:U11>
         <PDBx:U12>-0.0113</PDBx:U12>
         <PDBx:U13>0.0220</PDBx:U13>
         <PDBx:U22>0.2719</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.2605</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="687">
         <PDBx:U11>0.2766</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>0.0213</PDBx:U13>
         <PDBx:U22>0.2669</PDBx:U22>
         <PDBx:U23>-0.0078</PDBx:U23>
         <PDBx:U33>0.2549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="688">
         <PDBx:U11>0.2692</PDBx:U11>
         <PDBx:U12>-0.0097</PDBx:U12>
         <PDBx:U13>0.0201</PDBx:U13>
         <PDBx:U22>0.2642</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.2515</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="689">
         <PDBx:U11>0.3016</PDBx:U11>
         <PDBx:U12>-0.0134</PDBx:U12>
         <PDBx:U13>0.0252</PDBx:U13>
         <PDBx:U22>0.2857</PDBx:U22>
         <PDBx:U23>-0.0088</PDBx:U23>
         <PDBx:U33>0.2731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="690">
         <PDBx:U11>0.3128</PDBx:U11>
         <PDBx:U12>-0.0160</PDBx:U12>
         <PDBx:U13>0.0245</PDBx:U13>
         <PDBx:U22>0.2913</PDBx:U22>
         <PDBx:U23>-0.0086</PDBx:U23>
         <PDBx:U33>0.2790</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="691">
         <PDBx:U11>0.2869</PDBx:U11>
         <PDBx:U12>-0.0155</PDBx:U12>
         <PDBx:U13>0.0211</PDBx:U13>
         <PDBx:U22>0.2662</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.2544</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="692">
         <PDBx:U11>0.2868</PDBx:U11>
         <PDBx:U12>-0.0066</PDBx:U12>
         <PDBx:U13>0.0219</PDBx:U13>
         <PDBx:U22>0.2770</PDBx:U22>
         <PDBx:U23>-0.0078</PDBx:U23>
         <PDBx:U33>0.2654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="693">
         <PDBx:U11>0.2886</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>0.0207</PDBx:U13>
         <PDBx:U22>0.2834</PDBx:U22>
         <PDBx:U23>-0.0076</PDBx:U23>
         <PDBx:U33>0.2716</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="694">
         <PDBx:U11>0.2908</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.0218</PDBx:U13>
         <PDBx:U22>0.2940</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.2803</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="695">
         <PDBx:U11>0.2995</PDBx:U11>
         <PDBx:U12>-0.0015</PDBx:U12>
         <PDBx:U13>0.0202</PDBx:U13>
         <PDBx:U22>0.3068</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.2927</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="696">
         <PDBx:U11>0.2966</PDBx:U11>
         <PDBx:U12>-0.0016</PDBx:U12>
         <PDBx:U13>0.0215</PDBx:U13>
         <PDBx:U22>0.2872</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.2762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="697">
         <PDBx:U11>0.2957</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>0.0241</PDBx:U13>
         <PDBx:U22>0.2819</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.2711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="698">
         <PDBx:U11>0.2949</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0235</PDBx:U13>
         <PDBx:U22>0.2790</PDBx:U22>
         <PDBx:U23>-0.0078</PDBx:U23>
         <PDBx:U33>0.2682</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="699">
         <PDBx:U11>0.3188</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>0.0242</PDBx:U13>
         <PDBx:U22>0.3245</PDBx:U22>
         <PDBx:U23>-0.0090</PDBx:U23>
         <PDBx:U33>0.3094</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="700">
         <PDBx:U11>0.3134</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0252</PDBx:U13>
         <PDBx:U22>0.3282</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.3106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="701">
         <PDBx:U11>0.3114</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0241</PDBx:U13>
         <PDBx:U22>0.3291</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.3104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="702">
         <PDBx:U11>0.3383</PDBx:U11>
         <PDBx:U12>-0.0096</PDBx:U12>
         <PDBx:U13>0.0248</PDBx:U13>
         <PDBx:U22>0.3635</PDBx:U22>
         <PDBx:U23>-0.0105</PDBx:U23>
         <PDBx:U33>0.3423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="703">
         <PDBx:U11>0.3534</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0291</PDBx:U13>
         <PDBx:U22>0.3704</PDBx:U22>
         <PDBx:U23>-0.0107</PDBx:U23>
         <PDBx:U33>0.3513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="704">
         <PDBx:U11>0.3862</PDBx:U11>
         <PDBx:U12>-0.0090</PDBx:U12>
         <PDBx:U13>0.0310</PDBx:U13>
         <PDBx:U22>0.3979</PDBx:U22>
         <PDBx:U23>-0.0111</PDBx:U23>
         <PDBx:U33>0.3791</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="705">
         <PDBx:U11>0.4017</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0297</PDBx:U13>
         <PDBx:U22>0.4052</PDBx:U22>
         <PDBx:U23>-0.0105</PDBx:U23>
         <PDBx:U33>0.3885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="706">
         <PDBx:U11>0.4745</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>0.0340</PDBx:U13>
         <PDBx:U22>0.4902</PDBx:U22>
         <PDBx:U23>-0.0121</PDBx:U23>
         <PDBx:U33>0.4692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="707">
         <PDBx:U11>0.2687</PDBx:U11>
         <PDBx:U12>-0.0104</PDBx:U12>
         <PDBx:U13>0.0222</PDBx:U13>
         <PDBx:U22>0.2806</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.2635</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="708">
         <PDBx:U11>0.2636</PDBx:U11>
         <PDBx:U12>-0.0134</PDBx:U12>
         <PDBx:U13>0.0212</PDBx:U13>
         <PDBx:U22>0.2767</PDBx:U22>
         <PDBx:U23>-0.0093</PDBx:U23>
         <PDBx:U33>0.2587</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="709">
         <PDBx:U11>0.2327</PDBx:U11>
         <PDBx:U12>-0.0123</PDBx:U12>
         <PDBx:U13>0.0186</PDBx:U13>
         <PDBx:U22>0.2506</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.2321</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="710">
         <PDBx:U11>0.2153</PDBx:U11>
         <PDBx:U12>-0.0095</PDBx:U12>
         <PDBx:U13>0.0169</PDBx:U13>
         <PDBx:U22>0.2328</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.2154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="711">
         <PDBx:U11>0.2922</PDBx:U11>
         <PDBx:U12>-0.0151</PDBx:U12>
         <PDBx:U13>0.0203</PDBx:U13>
         <PDBx:U22>0.2971</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.2808</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="712">
         <PDBx:U11>0.3279</PDBx:U11>
         <PDBx:U12>-0.0174</PDBx:U12>
         <PDBx:U13>0.0229</PDBx:U13>
         <PDBx:U22>0.3283</PDBx:U22>
         <PDBx:U23>-0.0094</PDBx:U23>
         <PDBx:U33>0.3119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="713">
         <PDBx:U11>0.3608</PDBx:U11>
         <PDBx:U12>-0.0195</PDBx:U12>
         <PDBx:U13>0.0225</PDBx:U13>
         <PDBx:U22>0.3544</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.3386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="714">
         <PDBx:U11>0.3799</PDBx:U11>
         <PDBx:U12>-0.0177</PDBx:U12>
         <PDBx:U13>0.0260</PDBx:U13>
         <PDBx:U22>0.3814</PDBx:U22>
         <PDBx:U23>-0.0102</PDBx:U23>
         <PDBx:U33>0.3640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="715">
         <PDBx:U11>0.3810</PDBx:U11>
         <PDBx:U12>-0.0214</PDBx:U12>
         <PDBx:U13>0.0251</PDBx:U13>
         <PDBx:U22>0.3712</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.3551</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="716">
         <PDBx:U11>0.3788</PDBx:U11>
         <PDBx:U12>-0.0204</PDBx:U12>
         <PDBx:U13>0.0274</PDBx:U13>
         <PDBx:U22>0.3739</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.3568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="717">
         <PDBx:U11>0.2196</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>0.0183</PDBx:U13>
         <PDBx:U22>0.2417</PDBx:U22>
         <PDBx:U23>-0.0094</PDBx:U23>
         <PDBx:U33>0.2214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="718">
         <PDBx:U11>0.2176</PDBx:U11>
         <PDBx:U12>-0.0142</PDBx:U12>
         <PDBx:U13>0.0159</PDBx:U13>
         <PDBx:U22>0.2441</PDBx:U22>
         <PDBx:U23>-0.0091</PDBx:U23>
         <PDBx:U33>0.2230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="719">
         <PDBx:U11>0.1851</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>0.0133</PDBx:U13>
         <PDBx:U22>0.2062</PDBx:U22>
         <PDBx:U23>-0.0081</PDBx:U23>
         <PDBx:U33>0.1874</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="720">
         <PDBx:U11>0.1772</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>0.2007</PDBx:U22>
         <PDBx:U23>-0.0077</PDBx:U23>
         <PDBx:U33>0.1820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="721">
         <PDBx:U11>0.2591</PDBx:U11>
         <PDBx:U12>-0.0181</PDBx:U12>
         <PDBx:U13>0.0160</PDBx:U13>
         <PDBx:U22>0.2891</PDBx:U22>
         <PDBx:U23>-0.0096</PDBx:U23>
         <PDBx:U33>0.2657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="722">
         <PDBx:U11>0.3069</PDBx:U11>
         <PDBx:U12>-0.0190</PDBx:U12>
         <PDBx:U13>0.0176</PDBx:U13>
         <PDBx:U22>0.3463</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
         <PDBx:U33>0.3195</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="723">
         <PDBx:U11>0.3405</PDBx:U11>
         <PDBx:U12>-0.0161</PDBx:U12>
         <PDBx:U13>0.0187</PDBx:U13>
         <PDBx:U22>0.3842</PDBx:U22>
         <PDBx:U23>-0.0108</PDBx:U23>
         <PDBx:U33>0.3567</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="724">
         <PDBx:U11>0.3646</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>0.0176</PDBx:U13>
         <PDBx:U22>0.4072</PDBx:U22>
         <PDBx:U23>-0.0112</PDBx:U23>
         <PDBx:U33>0.3780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="725">
         <PDBx:U11>0.1691</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>0.0132</PDBx:U13>
         <PDBx:U22>0.1833</PDBx:U22>
         <PDBx:U23>-0.0078</PDBx:U23>
         <PDBx:U33>0.1661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="726">
         <PDBx:U11>0.1585</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>0.0110</PDBx:U13>
         <PDBx:U22>0.1687</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.1531</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="727">
         <PDBx:U11>0.1474</PDBx:U11>
         <PDBx:U12>-0.0098</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.1570</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.1427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="728">
         <PDBx:U11>0.1373</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0083</PDBx:U13>
         <PDBx:U22>0.1464</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.1326</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="729">
         <PDBx:U11>0.1665</PDBx:U11>
         <PDBx:U12>-0.0143</PDBx:U12>
         <PDBx:U13>0.0109</PDBx:U13>
         <PDBx:U22>0.1698</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.1554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="730">
         <PDBx:U11>0.1729</PDBx:U11>
         <PDBx:U12>-0.0136</PDBx:U12>
         <PDBx:U13>0.0119</PDBx:U13>
         <PDBx:U22>0.1718</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.1583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="731">
         <PDBx:U11>0.1771</PDBx:U11>
         <PDBx:U12>-0.0132</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.1782</PDBx:U22>
         <PDBx:U23>-0.0061</PDBx:U23>
         <PDBx:U33>0.1646</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="732">
         <PDBx:U11>0.1500</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>0.0118</PDBx:U13>
         <PDBx:U22>0.1589</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.1448</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="733">
         <PDBx:U11>0.1442</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>0.0113</PDBx:U13>
         <PDBx:U22>0.1518</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.1387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="734">
         <PDBx:U11>0.1438</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>0.0105</PDBx:U13>
         <PDBx:U22>0.1564</PDBx:U22>
         <PDBx:U23>-0.0062</PDBx:U23>
         <PDBx:U33>0.1424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="735">
         <PDBx:U11>0.1483</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.1594</PDBx:U22>
         <PDBx:U23>-0.0057</PDBx:U23>
         <PDBx:U33>0.1463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="736">
         <PDBx:U11>0.1540</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>0.0134</PDBx:U13>
         <PDBx:U22>0.1588</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.1460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="737">
         <PDBx:U11>0.1598</PDBx:U11>
         <PDBx:U12>-0.0029</PDBx:U12>
         <PDBx:U13>0.0131</PDBx:U13>
         <PDBx:U22>0.1628</PDBx:U22>
         <PDBx:U23>-0.0062</PDBx:U23>
         <PDBx:U33>0.1509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="738">
         <PDBx:U11>0.1562</PDBx:U11>
         <PDBx:U12>-0.0074</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.1551</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.1432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="739">
         <PDBx:U11>0.1394</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>0.0114</PDBx:U13>
         <PDBx:U22>0.1581</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.1423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="740">
         <PDBx:U11>0.1389</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.1628</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.1458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="741">
         <PDBx:U11>0.1329</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.1565</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.1398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="742">
         <PDBx:U11>0.1339</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.1576</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.1411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="743">
         <PDBx:U11>0.1425</PDBx:U11>
         <PDBx:U12>-0.0026</PDBx:U12>
         <PDBx:U13>0.0114</PDBx:U13>
         <PDBx:U22>0.1742</PDBx:U22>
         <PDBx:U23>-0.0076</PDBx:U23>
         <PDBx:U33>0.1545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="744">
         <PDBx:U11>0.1286</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.1509</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.1342</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="745">
         <PDBx:U11>0.1310</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.1522</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.1358</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="746">
         <PDBx:U11>0.1288</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.1450</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.1305</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="747">
         <PDBx:U11>0.1301</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1464</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.1320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="748">
         <PDBx:U11>0.1450</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>0.0054</PDBx:U13>
         <PDBx:U22>0.1645</PDBx:U22>
         <PDBx:U23>-0.0061</PDBx:U23>
         <PDBx:U33>0.1479</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="749">
         <PDBx:U11>0.1482</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>0.0062</PDBx:U13>
         <PDBx:U22>0.1727</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.1538</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="750">
         <PDBx:U11>0.2028</PDBx:U11>
         <PDBx:U12>-0.0155</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.2233</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.2041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="751">
         <PDBx:U11>0.2129</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.2403</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.2178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="752">
         <PDBx:U11>0.1270</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.1389</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.1255</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="753">
         <PDBx:U11>0.1250</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.1330</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1208</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="754">
         <PDBx:U11>0.1279</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>0.0038</PDBx:U13>
         <PDBx:U22>0.1359</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="755">
         <PDBx:U11>0.1326</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1391</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1275</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="756">
         <PDBx:U11>0.1288</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.1329</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="757">
         <PDBx:U11>0.1308</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1403</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.1280</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="758">
         <PDBx:U11>0.1427</PDBx:U11>
         <PDBx:U12>0.0022</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.1513</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="759">
         <PDBx:U11>0.1344</PDBx:U11>
         <PDBx:U12>0.0032</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.1456</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="760">
         <PDBx:U11>0.1405</PDBx:U11>
         <PDBx:U12>0.0045</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.1488</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1365</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="761">
         <PDBx:U11>0.1631</PDBx:U11>
         <PDBx:U12>0.0041</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.1733</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.1607</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="762">
         <PDBx:U11>0.1908</PDBx:U11>
         <PDBx:U12>0.0034</PDBx:U12>
         <PDBx:U13>0.0084</PDBx:U13>
         <PDBx:U22>0.1968</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1851</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="763">
         <PDBx:U11>0.2427</PDBx:U11>
         <PDBx:U12>0.0050</PDBx:U12>
         <PDBx:U13>0.0106</PDBx:U13>
         <PDBx:U22>0.2508</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.2383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="764">
         <PDBx:U11>0.3010</PDBx:U11>
         <PDBx:U12>0.0085</PDBx:U12>
         <PDBx:U13>0.0108</PDBx:U13>
         <PDBx:U22>0.3073</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.2950</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="765">
         <PDBx:U11>0.3685</PDBx:U11>
         <PDBx:U12>0.0111</PDBx:U12>
         <PDBx:U13>0.0127</PDBx:U13>
         <PDBx:U22>0.3769</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.3638</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="766">
         <PDBx:U11>0.4075</PDBx:U11>
         <PDBx:U12>0.0103</PDBx:U12>
         <PDBx:U13>0.0145</PDBx:U13>
         <PDBx:U22>0.4210</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.4065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="767">
         <PDBx:U11>0.4078</PDBx:U11>
         <PDBx:U12>0.0147</PDBx:U12>
         <PDBx:U13>0.0128</PDBx:U13>
         <PDBx:U22>0.4133</PDBx:U22>
         <PDBx:U23>-0.0057</PDBx:U23>
         <PDBx:U33>0.4005</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="768">
         <PDBx:U11>0.1310</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1473</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1332</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="769">
         <PDBx:U11>0.1336</PDBx:U11>
         <PDBx:U12>0.0031</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1525</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1374</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="770">
         <PDBx:U11>0.1240</PDBx:U11>
         <PDBx:U12>0.0019</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1392</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="771">
         <PDBx:U11>0.1330</PDBx:U11>
         <PDBx:U12>0.0031</PDBx:U12>
         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.1466</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1326</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="772">
         <PDBx:U11>0.1419</PDBx:U11>
         <PDBx:U12>0.0018</PDBx:U12>
         <PDBx:U13>0.0005</PDBx:U13>
         <PDBx:U22>0.1672</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.1501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="773">
         <PDBx:U11>0.1619</PDBx:U11>
         <PDBx:U12>0.0036</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.1926</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.1738</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="774">
         <PDBx:U11>0.1901</PDBx:U11>
         <PDBx:U12>0.0013</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.2275</PDBx:U22>
         <PDBx:U23>-0.0060</PDBx:U23>
         <PDBx:U33>0.2063</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="775">
         <PDBx:U11>0.1842</PDBx:U11>
         <PDBx:U12>0.0011</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.2255</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.2026</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="776">
         <PDBx:U11>0.1896</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.2382</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.2123</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="777">
         <PDBx:U11>0.1163</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.1299</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1163</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="778">
         <PDBx:U11>0.1168</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>-0.0011</PDBx:U13>
         <PDBx:U22>0.1274</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="779">
         <PDBx:U11>0.1161</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.1226</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.1106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="780">
         <PDBx:U11>0.1190</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.1237</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1117</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="781">
         <PDBx:U11>0.1201</PDBx:U11>
         <PDBx:U12>-0.0033</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1300</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1172</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="782">
         <PDBx:U11>0.1255</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>-0.0015</PDBx:U13>
         <PDBx:U22>0.1336</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.1209</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="783">
         <PDBx:U11>0.1304</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>-0.0027</PDBx:U13>
         <PDBx:U22>0.1403</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.1268</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="784">
         <PDBx:U11>0.1328</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1393</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1268</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="785">
         <PDBx:U11>0.1131</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1178</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1063</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="786">
         <PDBx:U11>0.1186</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1192</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1083</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="787">
         <PDBx:U11>0.1252</PDBx:U11>
         <PDBx:U12>0.0020</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.1241</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1132</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="788">
         <PDBx:U11>0.1237</PDBx:U11>
         <PDBx:U12>0.0016</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.1192</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="789">
         <PDBx:U11>0.1225</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.1208</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1103</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="790">
         <PDBx:U11>0.1400</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.1338</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1235</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="791">
         <PDBx:U11>0.1609</PDBx:U11>
         <PDBx:U12>-0.0017</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.1522</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1420</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="792">
         <PDBx:U11>0.1700</PDBx:U11>
         <PDBx:U12>-0.0016</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1621</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="793">
         <PDBx:U11>0.1819</PDBx:U11>
         <PDBx:U12>-0.0031</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.1702</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1596</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="794">
         <PDBx:U11>0.1355</PDBx:U11>
         <PDBx:U12>0.0041</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1371</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="795">
         <PDBx:U11>0.1482</PDBx:U11>
         <PDBx:U12>0.0065</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.1483</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1367</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="796">
         <PDBx:U11>0.1489</PDBx:U11>
         <PDBx:U12>0.0065</PDBx:U12>
         <PDBx:U13>-0.0015</PDBx:U13>
         <PDBx:U22>0.1488</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1373</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="797">
         <PDBx:U11>0.1424</PDBx:U11>
         <PDBx:U12>0.0057</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.1419</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1301</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="798">
         <PDBx:U11>0.1493</PDBx:U11>
         <PDBx:U12>0.0062</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.1444</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.1329</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="799">
         <PDBx:U11>0.1662</PDBx:U11>
         <PDBx:U12>0.0090</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.1711</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="800">
         <PDBx:U11>0.1663</PDBx:U11>
         <PDBx:U12>0.0092</PDBx:U12>
         <PDBx:U13>-0.0015</PDBx:U13>
         <PDBx:U22>0.1707</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1581</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="801">
         <PDBx:U11>0.1942</PDBx:U11>
         <PDBx:U12>0.0109</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.1988</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.1862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="802">
         <PDBx:U11>0.1920</PDBx:U11>
         <PDBx:U12>0.0126</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.1939</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1811</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="803">
         <PDBx:U11>0.2249</PDBx:U11>
         <PDBx:U12>0.0103</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.2243</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.2129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="804">
         <PDBx:U11>0.2320</PDBx:U11>
         <PDBx:U12>0.0143</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.2289</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.2170</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="805">
         <PDBx:U11>0.2299</PDBx:U11>
         <PDBx:U12>0.0128</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.2395</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.2257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="806">
         <PDBx:U11>0.2383</PDBx:U11>
         <PDBx:U12>0.0136</PDBx:U12>
         <PDBx:U13>-0.0041</PDBx:U13>
         <PDBx:U22>0.2424</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.2287</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="807">
         <PDBx:U11>0.1315</PDBx:U11>
         <PDBx:U12>0.0042</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.1349</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1225</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="808">
         <PDBx:U11>0.1330</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>-0.0050</PDBx:U13>
         <PDBx:U22>0.1355</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1228</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="809">
         <PDBx:U11>0.1243</PDBx:U11>
         <PDBx:U12>0.0017</PDBx:U12>
         <PDBx:U13>-0.0045</PDBx:U13>
         <PDBx:U22>0.1223</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.1103</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="810">
         <PDBx:U11>0.1319</PDBx:U11>
         <PDBx:U12>0.0018</PDBx:U12>
         <PDBx:U13>-0.0050</PDBx:U13>
         <PDBx:U22>0.1266</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1146</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="811">
         <PDBx:U11>0.1444</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>-0.0053</PDBx:U13>
         <PDBx:U22>0.1507</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1374</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="812">
         <PDBx:U11>0.1473</PDBx:U11>
         <PDBx:U12>0.0004</PDBx:U12>
         <PDBx:U13>-0.0063</PDBx:U13>
         <PDBx:U22>0.1519</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="813">
         <PDBx:U11>0.1567</PDBx:U11>
         <PDBx:U12>0.0025</PDBx:U12>
         <PDBx:U13>-0.0059</PDBx:U13>
         <PDBx:U22>0.1682</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="814">
         <PDBx:U11>0.1133</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>-0.0033</PDBx:U13>
         <PDBx:U22>0.1115</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0998</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="815">
         <PDBx:U11>0.1089</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.1045</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="816">
         <PDBx:U11>0.1100</PDBx:U11>
         <PDBx:U12>-0.0011</PDBx:U12>
         <PDBx:U13>-0.0027</PDBx:U13>
         <PDBx:U22>0.1010</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0894</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="817">
         <PDBx:U11>0.1159</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>-0.0028</PDBx:U13>
         <PDBx:U22>0.1042</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0923</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="818">
         <PDBx:U11>0.1089</PDBx:U11>
         <PDBx:U12>-0.0025</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.1060</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0943</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="819">
         <PDBx:U11>0.1112</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.1067</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0944</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="820">
         <PDBx:U11>0.1182</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.1146</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="821">
         <PDBx:U11>0.1227</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>-0.0011</PDBx:U13>
         <PDBx:U22>0.1157</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1033</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="822">
         <PDBx:U11>0.1312</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.1273</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1130</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="823">
         <PDBx:U11>0.1307</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1228</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1093</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="824">
         <PDBx:U11>0.1333</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>-0.0011</PDBx:U13>
         <PDBx:U22>0.1274</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="825">
         <PDBx:U11>0.1098</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.0993</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0882</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="826">
         <PDBx:U11>0.1200</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.1037</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="827">
         <PDBx:U11>0.1251</PDBx:U11>
         <PDBx:U12>0.0014</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.1051</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.0943</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="828">
         <PDBx:U11>0.1338</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.1087</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.0977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="829">
         <PDBx:U11>0.1311</PDBx:U11>
         <PDBx:U12>0.0014</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1131</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.1028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="830">
         <PDBx:U11>0.1341</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1180</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.1076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="831">
         <PDBx:U11>0.1476</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.1296</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.1185</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="832">
         <PDBx:U11>0.1615</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1398</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.1282</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="833">
         <PDBx:U11>0.1477</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1320</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1206</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="834">
         <PDBx:U11>0.1294</PDBx:U11>
         <PDBx:U12>0.0039</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1117</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.1009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="835">
         <PDBx:U11>0.1432</PDBx:U11>
         <PDBx:U12>0.0056</PDBx:U12>
         <PDBx:U13>-0.0047</PDBx:U13>
         <PDBx:U22>0.1216</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.1107</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="836">
         <PDBx:U11>0.1416</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>-0.0052</PDBx:U13>
         <PDBx:U22>0.1185</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.1073</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="837">
         <PDBx:U11>0.1626</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>-0.0054</PDBx:U13>
         <PDBx:U22>0.1336</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1223</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="838">
         <PDBx:U11>0.1607</PDBx:U11>
         <PDBx:U12>0.0091</PDBx:U12>
         <PDBx:U13>-0.0059</PDBx:U13>
         <PDBx:U22>0.1425</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.1313</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="839">
         <PDBx:U11>0.1877</PDBx:U11>
         <PDBx:U12>0.0121</PDBx:U12>
         <PDBx:U13>-0.0052</PDBx:U13>
         <PDBx:U22>0.1678</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.1568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="840">
         <PDBx:U11>0.2109</PDBx:U11>
         <PDBx:U12>0.0150</PDBx:U12>
         <PDBx:U13>-0.0058</PDBx:U13>
         <PDBx:U22>0.1849</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1740</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="841">
         <PDBx:U11>0.2020</PDBx:U11>
         <PDBx:U12>0.0120</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.1851</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.1743</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="842">
         <PDBx:U11>0.2305</PDBx:U11>
         <PDBx:U12>0.0182</PDBx:U12>
         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.2022</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="843">
         <PDBx:U11>0.2138</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>-0.0028</PDBx:U13>
         <PDBx:U22>0.1946</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.1841</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="844">
         <PDBx:U11>0.2332</PDBx:U11>
         <PDBx:U12>0.0181</PDBx:U12>
         <PDBx:U13>-0.0034</PDBx:U13>
         <PDBx:U22>0.2084</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.1980</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="845">
         <PDBx:U11>0.1322</PDBx:U11>
         <PDBx:U12>0.0017</PDBx:U12>
         <PDBx:U13>-0.0052</PDBx:U13>
         <PDBx:U22>0.1138</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.1021</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="846">
         <PDBx:U11>0.1341</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>-0.0054</PDBx:U13>
         <PDBx:U22>0.1142</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.1021</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="847">
         <PDBx:U11>0.1291</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>-0.0039</PDBx:U13>
         <PDBx:U22>0.1071</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.0945</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="848">
         <PDBx:U11>0.1357</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.1097</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.0967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="849">
         <PDBx:U11>0.1378</PDBx:U11>
         <PDBx:U12>-0.0007</PDBx:U12>
         <PDBx:U13>-0.0058</PDBx:U13>
         <PDBx:U22>0.1228</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.1103</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="850">
         <PDBx:U11>0.1493</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>-0.0058</PDBx:U13>
         <PDBx:U22>0.1320</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.1190</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="851">
         <PDBx:U11>0.1560</PDBx:U11>
         <PDBx:U12>-0.0025</PDBx:U12>
         <PDBx:U13>-0.0065</PDBx:U13>
         <PDBx:U22>0.1420</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.1288</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="852">
         <PDBx:U11>0.1647</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>-0.0060</PDBx:U13>
         <PDBx:U22>0.1483</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.1347</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="853">
         <PDBx:U11>0.1555</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>-0.0062</PDBx:U13>
         <PDBx:U22>0.1404</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="854">
         <PDBx:U11>0.1476</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.1359</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="855">
         <PDBx:U11>0.1617</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>-0.0053</PDBx:U13>
         <PDBx:U22>0.1442</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="856">
         <PDBx:U11>0.1290</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>-0.0030</PDBx:U13>
         <PDBx:U22>0.1095</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.0968</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="857">
         <PDBx:U11>0.1304</PDBx:U11>
         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.1098</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="858">
         <PDBx:U11>0.1381</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.1107</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0969</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="859">
         <PDBx:U11>0.1479</PDBx:U11>
         <PDBx:U12>-0.0104</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.1184</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.1034</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="860">
         <PDBx:U11>0.1270</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.1098</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0959</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="861">
         <PDBx:U11>0.1292</PDBx:U11>
         <PDBx:U12>-0.0103</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1123</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0969</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="862">
         <PDBx:U11>0.1372</PDBx:U11>
         <PDBx:U12>-0.0119</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.1244</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1075</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="863">
         <PDBx:U11>0.1437</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.1234</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="864">
         <PDBx:U11>0.1412</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.1303</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1113</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="865">
         <PDBx:U11>0.1553</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.1362</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="866">
         <PDBx:U11>0.1489</PDBx:U11>
         <PDBx:U12>-0.0162</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.1352</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.1156</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="867">
         <PDBx:U11>0.1743</PDBx:U11>
         <PDBx:U12>-0.0193</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.1630</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.1408</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="868">
         <PDBx:U11>0.1440</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.1127</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.1000</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0017</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0016</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.1167</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.1541</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.1411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U12>-0.0062</PDBx:U12>
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         <PDBx:U22>0.1882</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.1748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.2086</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1937</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="876">
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         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.2550</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.2397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="877">
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         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.2043</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="878">
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         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.2206</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="879">
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         <PDBx:U22>0.2896</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.2774</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="880">
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         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.3144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.3660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0022</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.2455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0028</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>CYSTEINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLN">
         <PDBx:formula>C5 H10 N2 O3</PDBx:formula>
         <PDBx:formula_weight>146.144</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLUTAMINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLU">
         <PDBx:formula>C5 H9 N O4</PDBx:formula>
         <PDBx:formula_weight>147.129</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLUTAMIC ACID</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLY">
         <PDBx:formula>C2 H5 N O2</PDBx:formula>
         <PDBx:formula_weight>75.067</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLYCINE</PDBx:name>
         <PDBx:type>peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GOL">
         <PDBx:formula>C3 H8 O3</PDBx:formula>
         <PDBx:formula_weight>92.094</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>GLYCEROL</PDBx:name>
         <PDBx:pdbx_synonyms>GLYCERIN; PROPANE-1,2,3-TRIOL</PDBx:pdbx_synonyms>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HIS">
         <PDBx:formula>C6 H10 N3 O2 1</PDBx:formula>
         <PDBx:formula_weight>156.162</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>HISTIDINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HOH">
         <PDBx:formula>H2 O</PDBx:formula>
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>WATER</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ILE">
         <PDBx:formula>C6 H13 N O2</PDBx:formula>
         <PDBx:formula_weight>131.173</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ISOLEUCINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="LEU">
         <PDBx:formula>C6 H13 N O2</PDBx:formula>
         <PDBx:formula_weight>131.173</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>LEUCINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="LYS">
         <PDBx:formula>C6 H15 N2 O2 1</PDBx:formula>
         <PDBx:formula_weight>147.195</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>LYSINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="MET">
         <PDBx:formula>C5 H11 N O2 S</PDBx:formula>
         <PDBx:formula_weight>149.211</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>METHIONINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="NI">
         <PDBx:formula>Ni 2</PDBx:formula>
         <PDBx:formula_weight>58.693</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>NICKEL (II) ION</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="PHE">
         <PDBx:formula>C9 H11 N O2</PDBx:formula>
         <PDBx:formula_weight>165.189</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>PHENYLALANINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="PRO">
         <PDBx:formula>C5 H9 N O2</PDBx:formula>
         <PDBx:formula_weight>115.130</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>PROLINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="SER">
         <PDBx:formula>C3 H7 N O3</PDBx:formula>
         <PDBx:formula_weight>105.093</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>SERINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="THR">
         <PDBx:formula>C4 H9 N O3</PDBx:formula>
         <PDBx:formula_weight>119.119</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>THREONINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="TRP">
         <PDBx:formula>C11 H12 N2 O2</PDBx:formula>
         <PDBx:formula_weight>204.225</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>TRYPTOPHAN</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="TYR">
         <PDBx:formula>C9 H11 N O3</PDBx:formula>
         <PDBx:formula_weight>181.189</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>TYROSINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="VAL">
         <PDBx:formula>C5 H11 N O2</PDBx:formula>
         <PDBx:formula_weight>117.146</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>VALINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
   </PDBx:chem_compCategory>
   <PDBx:citationCategory>
      <PDBx:citation id="primary">
         <PDBx:country>US</PDBx:country>
         <PDBx:journal_abbrev>J.Med.Chem.</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>JMCMAR</PDBx:journal_id_ASTM>
         <PDBx:journal_id_ISSN>0022-2623</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>59</PDBx:journal_volume>
         <PDBx:page_first>1492</PDBx:page_first>
         <PDBx:page_last>1500</PDBx:page_last>
         <PDBx:pdbx_database_id_DOI>10.1021/acs.jmedchem.5b01135</PDBx:pdbx_database_id_DOI>
         <PDBx:pdbx_database_id_PubMed>26367539</PDBx:pdbx_database_id_PubMed>
         <PDBx:title>New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition.</PDBx:title>
         <PDBx:year>2016</PDBx:year>
      </PDBx:citation>
   </PDBx:citationCategory>
   <PDBx:citation_authorCategory>
      <PDBx:citation_author citation_id="primary" name="Baud, M.G." ordinal="1"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Lin-Shiao, E." ordinal="2"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Zengerle, M." ordinal="3"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Tallant, C." ordinal="4"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Ciulli, A." ordinal="5"></PDBx:citation_author>
   </PDBx:citation_authorCategory>
   <PDBx:computingCategory>
      <PDBx:computing entry_id="5DFB">
         <PDBx:structure_refinement>REFMAC 5.7.0029</PDBx:structure_refinement>
      </PDBx:computing>
   </PDBx:computingCategory>
   <PDBx:database_2Category>
      <PDBx:database_2 database_code="5DFB" database_id="PDB"></PDBx:database_2>
      <PDBx:database_2 database_code="D_1000213122" database_id="WWPDB"></PDBx:database_2>
   </PDBx:database_2Category>
   <PDBx:database_PDB_revCategory>
      <PDBx:database_PDB_rev num="1">
         <PDBx:date>2015-11-11</PDBx:date>
         <PDBx:date_original>2015-08-26</PDBx:date_original>
         <PDBx:mod_type>0</PDBx:mod_type>
         <PDBx:replaces>5DFB</PDBx:replaces>
      </PDBx:database_PDB_rev>
      <PDBx:database_PDB_rev num="2">
         <PDBx:date>2016-03-09</PDBx:date>
         <PDBx:mod_type>1</PDBx:mod_type>
         <PDBx:replaces>5DFB</PDBx:replaces>
      </PDBx:database_PDB_rev>
   </PDBx:database_PDB_revCategory>
   <PDBx:database_PDB_rev_recordCategory>
      <PDBx:database_PDB_rev_record rev_num="2" type="JRNL">
      </PDBx:database_PDB_rev_record>
   </PDBx:database_PDB_rev_recordCategory>
   <PDBx:diffrnCategory>
      <PDBx:diffrn id="1">
         <PDBx:ambient_temp>100</PDBx:ambient_temp>
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
   </PDBx:diffrnCategory>
   <PDBx:diffrn_detectorCategory>
      <PDBx:diffrn_detector diffrn_id="1">
         <PDBx:detector>PIXEL</PDBx:detector>
         <PDBx:pdbx_collection_date>2012-10-18</PDBx:pdbx_collection_date>
         <PDBx:type>DECTRIS PILATUS 6M</PDBx:type>
      </PDBx:diffrn_detector>
   </PDBx:diffrn_detectorCategory>
   <PDBx:diffrn_radiationCategory>
      <PDBx:diffrn_radiation diffrn_id="1">
         <PDBx:pdbx_diffrn_protocol>SINGLE WAVELENGTH</PDBx:pdbx_diffrn_protocol>
         <PDBx:pdbx_monochromatic_or_laue_m_l>M</PDBx:pdbx_monochromatic_or_laue_m_l>
         <PDBx:pdbx_scattering_type>x-ray</PDBx:pdbx_scattering_type>
         <PDBx:wavelength_id>1</PDBx:wavelength_id>
      </PDBx:diffrn_radiation>
   </PDBx:diffrn_radiationCategory>
   <PDBx:diffrn_radiation_wavelengthCategory>
      <PDBx:diffrn_radiation_wavelength id="1">
         <PDBx:wavelength>0.9795</PDBx:wavelength>
         <PDBx:wt>1.0</PDBx:wt>
      </PDBx:diffrn_radiation_wavelength>
   </PDBx:diffrn_radiation_wavelengthCategory>
   <PDBx:diffrn_sourceCategory>
      <PDBx:diffrn_source diffrn_id="1">
         <PDBx:pdbx_synchrotron_beamline>I02</PDBx:pdbx_synchrotron_beamline>
         <PDBx:pdbx_synchrotron_site>DIAMOND</PDBx:pdbx_synchrotron_site>
         <PDBx:pdbx_wavelength_list>0.9795</PDBx:pdbx_wavelength_list>
         <PDBx:source>SYNCHROTRON</PDBx:source>
         <PDBx:type>DIAMOND BEAMLINE I02</PDBx:type>
      </PDBx:diffrn_source>
   </PDBx:diffrn_sourceCategory>
   <PDBx:entityCategory>
      <PDBx:entity id="1">
         <PDBx:formula_weight>13336.374</PDBx:formula_weight>
         <PDBx:pdbx_description>Bromodomain-containing protein 2</PDBx:pdbx_description>
         <PDBx:pdbx_fragment>UNP Residues 344-455</PDBx:pdbx_fragment>
         <PDBx:pdbx_mutation>W370F</PDBx:pdbx_mutation>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>man</PDBx:src_method>
         <PDBx:type>polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="2">
         <PDBx:formula_weight>58.693</PDBx:formula_weight>
         <PDBx:pdbx_description>NICKEL (II) ION</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="3">
         <PDBx:formula_weight>414.488</PDBx:formula_weight>
         <PDBx:pdbx_description>NONAETHYLENE GLYCOL</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="4">
         <PDBx:formula_weight>92.094</PDBx:formula_weight>
         <PDBx:pdbx_description>GLYCEROL</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="5">
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:pdbx_description>water</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>76</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>nat</PDBx:src_method>
         <PDBx:type>water</PDBx:type>
      </PDBx:entity>
   </PDBx:entityCategory>
   <PDBx:entity_name_comCategory>
      <PDBx:entity_name_com entity_id="1">
         <PDBx:name>O27.1.1,Really interesting new gene 3 protein</PDBx:name>
      </PDBx:entity_name_com>
   </PDBx:entity_name_comCategory>
   <PDBx:entity_polyCategory>
      <PDBx:entity_poly entity_id="1">
         <PDBx:nstd_linkage>no</PDBx:nstd_linkage>
         <PDBx:nstd_monomer>no</PDBx:nstd_monomer>
         <PDBx:pdbx_seq_one_letter_code>SMGKLSEQLKHCNGILKELLSKKHAAYAFPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLM
FSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD</PDBx:pdbx_seq_one_letter_code>
         <PDBx:pdbx_seq_one_letter_code_can>SMGKLSEQLKHCNGILKELLSKKHAAYAFPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLM
FSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD</PDBx:pdbx_seq_one_letter_code_can>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:type>polypeptide(L)</PDBx:type>
      </PDBx:entity_poly>
   </PDBx:entity_polyCategory>
   <PDBx:entity_poly_seqCategory>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="1">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="2">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="3">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="4">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="5">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="6">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="7">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="8">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="9">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="10">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="11">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="12">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="13">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="14">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="15">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="16">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="17">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="18">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="19">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="20">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="21">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="22">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="23">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="24">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="25">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="26">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="27">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="28">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="29">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="30">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="31">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="32">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="33">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="34">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="35">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="36">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="37">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="38">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="39">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="40">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="41">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="42">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="43">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="44">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="45">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="46">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="47">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="48">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="49">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="50">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="51">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="52">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="53">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="54">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="55">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="56">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="57">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="58">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="59">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="60">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="61">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="62">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="63">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="64">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="65">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="66">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="67">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="68">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="69">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="70">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="71">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="72">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="73">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="74">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="75">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="76">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="77">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="78">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="79">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="80">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="81">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="82">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="83">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="84">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="85">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="86">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="87">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="88">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="89">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="90">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="91">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="92">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="93">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="94">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="95">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="96">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="97">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="98">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="99">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="100">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="101">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="102">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="103">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="104">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="105">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="106">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="107">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="108">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="109">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="110">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="111">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="112">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="113">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="114">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
   </PDBx:entity_poly_seqCategory>
   <PDBx:entity_src_genCategory>
      <PDBx:entity_src_gen entity_id="1" pdbx_src_id="1">
         <PDBx:gene_src_common_name>Human</PDBx:gene_src_common_name>
         <PDBx:pdbx_alt_source_flag>sample</PDBx:pdbx_alt_source_flag>
         <PDBx:pdbx_beg_seq_num>1</PDBx:pdbx_beg_seq_num>
         <PDBx:pdbx_end_seq_num>114</PDBx:pdbx_end_seq_num>
         <PDBx:pdbx_gene_src_gene>BRD2, KIAA9001, RING3</PDBx:pdbx_gene_src_gene>
         <PDBx:pdbx_gene_src_ncbi_taxonomy_id>9606</PDBx:pdbx_gene_src_ncbi_taxonomy_id>
         <PDBx:pdbx_gene_src_scientific_name>Homo sapiens</PDBx:pdbx_gene_src_scientific_name>
         <PDBx:pdbx_host_org_ncbi_taxonomy_id>469008</PDBx:pdbx_host_org_ncbi_taxonomy_id>
         <PDBx:pdbx_host_org_scientific_name>Escherichia coli BL21(DE3)</PDBx:pdbx_host_org_scientific_name>
         <PDBx:pdbx_host_org_variant>Rosetta</PDBx:pdbx_host_org_variant>
         <PDBx:pdbx_host_org_vector_type>Plasmid</PDBx:pdbx_host_org_vector_type>
         <PDBx:pdbx_seq_type>Biological sequence</PDBx:pdbx_seq_type>
         <PDBx:plasmid_name>pNIC28-Bsa4</PDBx:plasmid_name>
      </PDBx:entity_src_gen>
   </PDBx:entity_src_genCategory>
   <PDBx:entryCategory>
      <PDBx:entry id="5DFB"></PDBx:entry>
   </PDBx:entryCategory>
   <PDBx:exptlCategory>
      <PDBx:exptl entry_id="5DFB" method="X-RAY DIFFRACTION">
      </PDBx:exptl>
   </PDBx:exptlCategory>
   <PDBx:exptl_crystalCategory>
      <PDBx:exptl_crystal id="1">
         <PDBx:density_Matthews>2.27</PDBx:density_Matthews>
         <PDBx:density_percent_sol>45.92</PDBx:density_percent_sol>
      </PDBx:exptl_crystal>
   </PDBx:exptl_crystalCategory>
   <PDBx:exptl_crystal_growCategory>
      <PDBx:exptl_crystal_grow crystal_id="1">
         <PDBx:method>VAPOR DIFFUSION, HANGING DROP</PDBx:method>
         <PDBx:pH>7</PDBx:pH>
         <PDBx:pdbx_details>0.1M Hepes pH 7, 0.2M Imidiazole, 41&#37; PEG 400</PDBx:pdbx_details>
         <PDBx:pdbx_pH_range>7</PDBx:pdbx_pH_range>
         <PDBx:temp>293.15</PDBx:temp>
      </PDBx:exptl_crystal_grow>
   </PDBx:exptl_crystal_growCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="5DFB">
         <PDBx:SG_entry>N</PDBx:SG_entry>
         <PDBx:date_begin_release_preparation xsi:nil="true" />
         <PDBx:deposit_site>RCSB</PDBx:deposit_site>
         <PDBx:pdb_format_compatible>Y</PDBx:pdb_format_compatible>
         <PDBx:process_site>RCSB</PDBx:process_site>
         <PDBx:status_code>REL</PDBx:status_code>
         <PDBx:status_code_sf>REL</PDBx:status_code_sf>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="2">
         <PDBx:comp_id>NI</PDBx:comp_id>
         <PDBx:name>NICKEL (II) ION</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="3">
         <PDBx:comp_id>2PE</PDBx:comp_id>
         <PDBx:name>NONAETHYLENE GLYCOL</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="4">
         <PDBx:comp_id>GOL</PDBx:comp_id>
         <PDBx:name>GLYCEROL</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="5">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="1">
         <PDBx:auth_mon_id>Ni</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>NI</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>NI</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>501</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="1">
         <PDBx:auth_mon_id>2PE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>2PE</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>2PE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>502</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="1">
         <PDBx:auth_mon_id>GOL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>GOL</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GOL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>503</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>61</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>601</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>25</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>602</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>59</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>603</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="4">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>16</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>604</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="5">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>15</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>605</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="6">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>606</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="7">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>31</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>607</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="8">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>13</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>608</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="9">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>20</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>609</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="10">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>54</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>610</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="11">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>36</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>611</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="12">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>57</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>612</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="13">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>613</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="14">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>42</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>614</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="15">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>39</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>615</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="16">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>72</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>616</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="17">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>60</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>617</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="18">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>618</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="19">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>73</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>619</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="20">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>27</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>620</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="21">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>48</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>621</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="22">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>19</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>622</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="23">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>75</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>623</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="24">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>7</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>624</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="25">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>46</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>625</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="26">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>14</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>626</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="27">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>627</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="28">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>17</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>628</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="29">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>38</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>629</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="30">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>18</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>630</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="31">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>32</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>631</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="32">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>76</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>632</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="33">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>21</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>633</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="34">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>8</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>634</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="35">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>53</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>635</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="36">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>26</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>636</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="37">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>9</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>637</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="38">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>70</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>638</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="39">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>22</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>639</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="40">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>34</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>640</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="41">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>11</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>641</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="42">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>642</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="43">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>35</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>643</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="44">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>40</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>644</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="45">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>37</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>645</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="46">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>74</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>646</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="47">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>64</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>647</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="48">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>67</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>648</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="49">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>10</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>649</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="50">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>44</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>650</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="51">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>58</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>651</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="52">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>24</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>652</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="53">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>30</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>653</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="54">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>55</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>654</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="55">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>29</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>655</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="56">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>69</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>656</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="57">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>33</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>657</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="58">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>658</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="59">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>71</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>659</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="60">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>12</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>660</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="61">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>28</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>661</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="62">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>23</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>662</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="63">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>49</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>663</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="64">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>45</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>664</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="65">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>47</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>665</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="66">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>63</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>666</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="67">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>52</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>667</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="68">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>56</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>668</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="69">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>65</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>669</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="70">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>62</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>670</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="71">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>68</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>671</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="72">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>66</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>672</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="73">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>50</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>673</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="74">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>51</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>674</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="75">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>41</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>675</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="76">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>43</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>676</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="1">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>342</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="2">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>343</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="3">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>344</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="4">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>345</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="5">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>346</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="6">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>347</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>347</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="7">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>348</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>348</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="8">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>349</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>349</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="9">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>350</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>350</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="10">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>351</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>351</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="11">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>352</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>352</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="12">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>353</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>353</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="13">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>354</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>354</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="14">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>355</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>14</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>355</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="15">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>356</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>15</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>356</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="16">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>357</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>16</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>357</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="17">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>358</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>17</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>358</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="18">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>359</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>18</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>359</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="19">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>360</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>19</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>360</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="20">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>361</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>20</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>361</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="21">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>362</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>21</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>362</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="22">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>363</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>22</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>363</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="23">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>364</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>23</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>364</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="24">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>365</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>24</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>365</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="25">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>366</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>25</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>366</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="26">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>367</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>26</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>367</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="27">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>368</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>27</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>368</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="28">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>369</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>28</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>369</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="29">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>370</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>29</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>370</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="30">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>371</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>30</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>371</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="31">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>372</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>31</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>372</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="32">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>373</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>32</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>373</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="33">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>374</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>33</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>374</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="34">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>375</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>34</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>375</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="35">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>376</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>35</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>376</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="36">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>377</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>36</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>377</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="37">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>378</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>37</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>378</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="38">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>379</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>38</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>379</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="39">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>380</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>39</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>380</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="40">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>381</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>40</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>381</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="41">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>382</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>41</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>382</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="42">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>383</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>42</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>383</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="43">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>384</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>43</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>384</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="44">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>385</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>44</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>385</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="45">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>386</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>45</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>386</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="46">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>387</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>46</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>387</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="47">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>388</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>47</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>388</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="48">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>389</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>48</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>389</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="49">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>390</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>49</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>390</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="50">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>391</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>50</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>391</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="51">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>392</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>51</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>392</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="52">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>393</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>52</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>393</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="53">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>394</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>53</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>394</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="54">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>395</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>54</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>395</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="55">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>396</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>55</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>396</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="56">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>397</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>56</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>397</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="57">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>398</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>57</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>398</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="58">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>399</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>58</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>399</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="59">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>400</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>59</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>400</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="60">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>401</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>60</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>401</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="61">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>402</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>61</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>402</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="62">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>403</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>62</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>403</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="63">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>404</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>63</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>404</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="64">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>405</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>64</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>405</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="65">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>406</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>65</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>406</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="66">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>407</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>66</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>407</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="67">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>408</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>67</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>408</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="68">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>409</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>68</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>409</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="69">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>410</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>69</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>410</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="70">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>411</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>70</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>411</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="71">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>412</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>71</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>412</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="72">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>413</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>72</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>413</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="73">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>414</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>73</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>414</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="74">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>415</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>74</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>415</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="75">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>416</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>75</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>416</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="76">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>417</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>76</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>417</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="77">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>418</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>77</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>418</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="78">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>419</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>78</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>419</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="79">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>420</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>79</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>420</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="80">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>421</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>80</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>421</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="81">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>422</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>81</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>422</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="82">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>423</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>82</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>423</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="83">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>424</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>83</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>424</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="84">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>425</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>84</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>425</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="85">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>426</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>85</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>426</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="86">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>427</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>86</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>427</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="87">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>428</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>87</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>428</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="88">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>429</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>88</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>429</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="89">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>430</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>89</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>430</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="90">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>431</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>90</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>431</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="91">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>432</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>91</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>432</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="92">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>433</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>92</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>433</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="93">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>434</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>93</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>434</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="94">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>435</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>94</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>435</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="95">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>436</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>95</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>436</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="96">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>437</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>96</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>437</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="97">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>438</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>97</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>438</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="98">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>439</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>98</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>439</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="99">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>440</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>99</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>440</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="100">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>441</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>100</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>441</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="101">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>442</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>101</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>442</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="102">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>443</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>102</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>443</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="103">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>444</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>103</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>444</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="104">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>445</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>104</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>445</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="105">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>446</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>105</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>446</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="106">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>447</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>106</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>447</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="107">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>448</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>107</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>448</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="108">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>449</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>108</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>449</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="109">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>450</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>109</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>450</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="110">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>451</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>110</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>451</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="111">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>452</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>111</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>452</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="112">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>453</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>112</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>453</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="113">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>454</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>113</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>454</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="114">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>114</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>455</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_refine_tlsCategory>
      <PDBx:pdbx_refine_tls id="1">
         <PDBx:L11>0.0128</PDBx:L11>
         <PDBx:L12>0.0543</PDBx:L12>
         <PDBx:L13>-0.0447</PDBx:L13>
         <PDBx:L22>0.3600</PDBx:L22>
         <PDBx:L23>0.0370</PDBx:L23>
         <PDBx:L33>0.6767</PDBx:L33>
         <PDBx:S11>-0.0013</PDBx:S11>
         <PDBx:S12>-0.0020</PDBx:S12>
         <PDBx:S13>-0.0005</PDBx:S13>
         <PDBx:S21>-0.0145</PDBx:S21>
         <PDBx:S22>0.0040</PDBx:S22>
         <PDBx:S23>-0.0097</PDBx:S23>
         <PDBx:S31>-0.0055</PDBx:S31>
         <PDBx:S32>-0.0110</PDBx:S32>
         <PDBx:S33>-0.0027</PDBx:S33>
         <PDBx:T11>0.0125</PDBx:T11>
         <PDBx:T12>-0.0049</PDBx:T12>
         <PDBx:T13>-0.0010</PDBx:T13>
         <PDBx:T22>0.0145</PDBx:T22>
         <PDBx:T23>-0.0028</PDBx:T23>
         <PDBx:T33>0.0013</PDBx:T33>
         <PDBx:details>Chain A</PDBx:details>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>-15.1028</PDBx:origin_x>
         <PDBx:origin_y>-15.9909</PDBx:origin_y>
         <PDBx:origin_z>2.5246</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
   </PDBx:pdbx_refine_tlsCategory>
   <PDBx:pdbx_refine_tls_groupCategory>
      <PDBx:pdbx_refine_tls_group id="1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>347</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>454</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>1</PDBx:refine_tls_id>
      </PDBx:pdbx_refine_tls_group>
   </PDBx:pdbx_refine_tls_groupCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_and_software_defined_assembly</PDBx:details>
         <PDBx:method_details>PISA</PDBx:method_details>
         <PDBx:oligomeric_count>2</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>dimeric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B,C,D,E" oper_expression="1,2"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_assembly_propCategory>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="ABSA (A^2)">
         <PDBx:value>2540</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="MORE">
         <PDBx:value>-25</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="SSA (A^2)">
         <PDBx:value>12580</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
   </PDBx:pdbx_struct_assembly_propCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="2">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>2_545</PDBx:name>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>-52.7310000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_struct_special_symmetryCategory>
      <PDBx:pdbx_struct_special_symmetry id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>NI</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>501</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_comp_id>NI</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
      </PDBx:pdbx_struct_special_symmetry>
   </PDBx:pdbx_struct_special_symmetryCategory>
   <PDBx:pdbx_unobs_or_zero_occ_atomsCategory>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C23</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>2PE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>C23</PDBx:label_atom_id>
         <PDBx:label_comp_id>2PE</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>N</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C24</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>2PE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>C24</PDBx:label_atom_id>
         <PDBx:label_comp_id>2PE</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>N</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O25</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>2PE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>O25</PDBx:label_atom_id>
         <PDBx:label_comp_id>2PE</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>N</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C26</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>2PE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>C26</PDBx:label_atom_id>
         <PDBx:label_comp_id>2PE</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>N</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C27</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>2PE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>C27</PDBx:label_atom_id>
         <PDBx:label_comp_id>2PE</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>N</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O28</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>2PE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>O28</PDBx:label_atom_id>
         <PDBx:label_comp_id>2PE</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>N</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
   </PDBx:pdbx_unobs_or_zero_occ_atomsCategory>
   <PDBx:pdbx_unobs_or_zero_occ_residuesCategory>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>342</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>344</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>3</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>345</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>4</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>346</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>5</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>455</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>114</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
   </PDBx:pdbx_unobs_or_zero_occ_residuesCategory>
   <PDBx:pdbx_validate_torsionCategory>
      <PDBx:pdbx_validate_torsion id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>-86.09</PDBx:phi>
         <PDBx:psi>40.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
   </PDBx:pdbx_validate_torsionCategory>
   <PDBx:pdbx_versionCategory>
      <PDBx:pdbx_version entry_id="5DFB" major_version="4" minor_version="0000" revision_type="Initial release">
         <PDBx:details>Initial release</PDBx:details>
         <PDBx:revision_date>2015-11-11</PDBx:revision_date>
      </PDBx:pdbx_version>
      <PDBx:pdbx_version entry_id="5DFB" major_version="4" minor_version="0001" revision_type="Citation">
         <PDBx:details>Citation</PDBx:details>
         <PDBx:revision_date>2016-03-09</PDBx:revision_date>
      </PDBx:pdbx_version>
   </PDBx:pdbx_versionCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="5DFB" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:B_iso_mean>14.809</PDBx:B_iso_mean>
         <PDBx:aniso_B11>0.11</PDBx:aniso_B11>
         <PDBx:aniso_B12>0.00</PDBx:aniso_B12>
         <PDBx:aniso_B13>0.00</PDBx:aniso_B13>
         <PDBx:aniso_B22>-0.07</PDBx:aniso_B22>
         <PDBx:aniso_B23>0.00</PDBx:aniso_B23>
         <PDBx:aniso_B33>-0.04</PDBx:aniso_B33>
         <PDBx:correlation_coeff_Fo_to_Fc>0.965</PDBx:correlation_coeff_Fo_to_Fc>
         <PDBx:correlation_coeff_Fo_to_Fc_free>0.963</PDBx:correlation_coeff_Fo_to_Fc_free>
         <PDBx:details>HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS</PDBx:details>
         <PDBx:ls_R_factor_R_free>0.16923</PDBx:ls_R_factor_R_free>
         <PDBx:ls_R_factor_R_work>0.15688</PDBx:ls_R_factor_R_work>
         <PDBx:ls_R_factor_obs>0.15755</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>1.40</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>29.58</PDBx:ls_d_res_low>
         <PDBx:ls_number_reflns_R_free>1250</PDBx:ls_number_reflns_R_free>
         <PDBx:ls_number_reflns_obs>23252</PDBx:ls_number_reflns_obs>
         <PDBx:ls_percent_reflns_R_free>5.1</PDBx:ls_percent_reflns_R_free>
         <PDBx:ls_percent_reflns_obs>99.54</PDBx:ls_percent_reflns_obs>
         <PDBx:overall_SU_B>1.224</PDBx:overall_SU_B>
         <PDBx:overall_SU_ML>0.025</PDBx:overall_SU_ML>
         <PDBx:pdbx_R_Free_selection_details>RANDOM</PDBx:pdbx_R_Free_selection_details>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_ls_cross_valid_method>THROUGHOUT</PDBx:pdbx_ls_cross_valid_method>
         <PDBx:pdbx_method_to_determine_struct>MOLECULAR REPLACEMENT</PDBx:pdbx_method_to_determine_struct>
         <PDBx:pdbx_overall_ESU_R>0.051</PDBx:pdbx_overall_ESU_R>
         <PDBx:pdbx_overall_ESU_R_Free>0.050</PDBx:pdbx_overall_ESU_R_Free>
         <PDBx:pdbx_solvent_ion_probe_radii>0.80</PDBx:pdbx_solvent_ion_probe_radii>
         <PDBx:pdbx_solvent_shrinkage_radii>0.80</PDBx:pdbx_solvent_shrinkage_radii>
         <PDBx:pdbx_solvent_vdw_probe_radii>1.20</PDBx:pdbx_solvent_vdw_probe_radii>
         <PDBx:pdbx_starting_model>2DVV</PDBx:pdbx_starting_model>
         <PDBx:pdbx_stereochemistry_target_values>MAXIMUM LIKELIHOOD</PDBx:pdbx_stereochemistry_target_values>
         <PDBx:solvent_model_details>MASK</PDBx:solvent_model_details>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="1" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>1.40</PDBx:d_res_high>
         <PDBx:d_res_low>29.58</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>76</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>996</PDBx:number_atoms_total>
         <PDBx:pdbx_number_atoms_ligand>29</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>0</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>891</PDBx:pdbx_number_atoms_protein>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_bond_refined_d">
         <PDBx:dev_ideal>0.012</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.019</PDBx:dev_ideal_target>
         <PDBx:number>947</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_bond_other_d">
         <PDBx:dev_ideal>0.001</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>905</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_angle_refined_deg">
         <PDBx:dev_ideal>1.507</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>1.976</PDBx:dev_ideal_target>
         <PDBx:number>1266</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_angle_other_deg">
         <PDBx:dev_ideal>0.808</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>3.000</PDBx:dev_ideal_target>
         <PDBx:number>2094</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_1_deg">
         <PDBx:dev_ideal>4.584</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>5.000</PDBx:dev_ideal_target>
         <PDBx:number>109</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_2_deg">
         <PDBx:dev_ideal>33.925</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>23.542</PDBx:dev_ideal_target>
         <PDBx:number>48</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_3_deg">
         <PDBx:dev_ideal>11.843</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>15.000</PDBx:dev_ideal_target>
         <PDBx:number>165</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_4_deg">
         <PDBx:dev_ideal>18.249</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>15.000</PDBx:dev_ideal_target>
         <PDBx:number>6</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_chiral_restr">
         <PDBx:dev_ideal>0.095</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>127</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_gen_planes_refined">
         <PDBx:dev_ideal>0.008</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.021</PDBx:dev_ideal_target>
         <PDBx:number>1032</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_gen_planes_other">
         <PDBx:dev_ideal>0.001</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>222</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_nbd_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_nbd_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_nbtor_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_nbtor_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_xyhbond_nbd_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_xyhbond_nbd_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_metal_ion_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_metal_ion_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_vdw_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_vdw_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_hbond_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_hbond_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_metal_ion_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_metal_ion_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcbond_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcbond_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcangle_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcangle_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_scbond_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_scbond_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_scangle_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_scangle_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_long_range_B_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_long_range_B_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_rigid_bond_restr">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_sphericity_free">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_sphericity_bonded">
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:refine_ls_shellCategory>
      <PDBx:refine_ls_shell d_res_high="1.400" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.158</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_work>0.155</PDBx:R_factor_R_work>
         <PDBx:d_res_low>1.436</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>83</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>1659</PDBx:number_reflns_R_work>
         <PDBx:pdbx_total_number_of_bins_used>20</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_obs>98.86</PDBx:percent_reflns_obs>
      </PDBx:refine_ls_shell>
   </PDBx:refine_ls_shellCategory>
   <PDBx:reflnsCategory>
      <PDBx:reflns pdbx_ordinal="1">
         <PDBx:d_resolution_high>1.40</PDBx:d_resolution_high>
         <PDBx:d_resolution_low>29.58</PDBx:d_resolution_low>
         <PDBx:entry_id>5DFB</PDBx:entry_id>
         <PDBx:number_all>24545</PDBx:number_all>
         <PDBx:number_obs>24545</PDBx:number_obs>
         <PDBx:pdbx_Rmerge_I_obs>0.035</PDBx:pdbx_Rmerge_I_obs>
         <PDBx:pdbx_Rsym_value>0.015</PDBx:pdbx_Rsym_value>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_netI_over_av_sigmaI>16.5</PDBx:pdbx_netI_over_av_sigmaI>
         <PDBx:pdbx_netI_over_sigmaI>34.1</PDBx:pdbx_netI_over_sigmaI>
         <PDBx:pdbx_redundancy>6.4</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_obs>99.6</PDBx:percent_possible_obs>
      </PDBx:reflns>
   </PDBx:reflnsCategory>
   <PDBx:reflns_shellCategory>
      <PDBx:reflns_shell pdbx_ordinal="1">
         <PDBx:Rmerge_I_obs>0.091</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.40</PDBx:d_res_high>
         <PDBx:d_res_low>1.48</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>16.5</PDBx:meanI_over_sigI_obs>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.4</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>99.0</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
   </PDBx:reflns_shellCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>REFMAC</PDBx:name>
         <PDBx:version>5.7.0029</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="2">
         <PDBx:classification>data reduction</PDBx:classification>
         <PDBx:name>XDS</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="3">
         <PDBx:classification>data scaling</PDBx:classification>
         <PDBx:name>SCALA</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="4">
         <PDBx:classification>phasing</PDBx:classification>
         <PDBx:name>PHASER</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="5DFB">
         <PDBx:pdbx_descriptor>Bromodomain-containing protein 2</PDBx:pdbx_descriptor>
         <PDBx:title>Crystal structure of BRD2(BD2) mutant W370F in the free form</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="C">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="D">
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="E">
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_confCategory>
      <PDBx:struct_conf id="HELX_P1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>347</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>6</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>361</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>20</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>15</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>362</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>21</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>364</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>23</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA2</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>3</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>HIS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>365</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>HIS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>24</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>PHE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>370</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>PHE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>29</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA3</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P4">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PRO</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>371</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PRO</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>30</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>TYR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>373</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>TYR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>32</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA4</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>3</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P5">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>377</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>36</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>382</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>41</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA5</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P6">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>385</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>44</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>390</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>49</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA6</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P7">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>395</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>54</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>405</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>64</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA7</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>11</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P8">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>410</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>69</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>429</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>88</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA8</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>20</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P9">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>HIS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>433</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>HIS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>92</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>451</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>110</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA9</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>19</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
   </PDBx:struct_confCategory>
   <PDBx:struct_conf_typeCategory>
      <PDBx:struct_conf_type id="HELX_P">
      </PDBx:struct_conf_type>
   </PDBx:struct_conf_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="5DFB">
         <PDBx:pdbx_keywords>TRANSCRIPTION</PDBx:pdbx_keywords>
         <PDBx:text>Transcription factors, BET bromodomains, protein mutation engineering, molecular probes, transcription</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>BRD2_HUMAN</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>344</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>P25440</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>GKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFS
NCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>344</PDBx:db_align_beg>
         <PDBx:db_align_end>455</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>5DFB</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>344</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>455</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P25440</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>3</PDBx:seq_align_beg>
         <PDBx:seq_align_end>114</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_ref_seq_difCategory>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="1">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:details>expression tag</PDBx:details>
         <PDBx:mon_id>SER</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>342</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>5DFB</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P25440</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:seq_num>1</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="2">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:details>expression tag</PDBx:details>
         <PDBx:mon_id>MET</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>343</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>5DFB</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P25440</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:seq_num>2</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="3">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>TRP</PDBx:db_mon_id>
         <PDBx:details>engineered mutation</PDBx:details>
         <PDBx:mon_id>PHE</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>370</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>5DFB</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P25440</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>370</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>29</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
   </PDBx:struct_ref_seq_difCategory>
   <PDBx:struct_siteCategory>
      <PDBx:struct_site id="AC1">
         <PDBx:details>binding site for residue NI A 501</PDBx:details>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>NI</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>4</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC2">
         <PDBx:details>binding site for residue 2PE A 502</PDBx:details>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>2PE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>8</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC3">
         <PDBx:details>binding site for residue GOL A 503</PDBx:details>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>GOL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>6</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
   </PDBx:struct_siteCategory>
   <PDBx:struct_site_genCategory>
      <PDBx:struct_site_gen id="1" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>419</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>78</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>2_545</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="2" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>419</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>78</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="3" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="4" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>2_545</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="5" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>347</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>6</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>8</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="6" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>351</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>10</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>8</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="7" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>385</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>44</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>8</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_445</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="8" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>428</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>87</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>8</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_445</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="9" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>429</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>88</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>8</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_445</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="10" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>623</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>8</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="11" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>646</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>8</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="12" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>648</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>8</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_445</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="13" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>402</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>61</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_655</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="14" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>407</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>66</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_655</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="15" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>438</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>97</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="16" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>441</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>100</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="17" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>601</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="18" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>615</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_655</PDBx:symmetry>
      </PDBx:struct_site_gen>
   </PDBx:struct_site_genCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="5DFB">
         <PDBx:Int_Tables_number>18</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>P 2 21 21</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
