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      <PDBx:atom_site id="98">
         <PDBx:B_iso_or_equiv>27.89</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>-2.242</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.032</PDBx:Cartn_z>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>6</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>OD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
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         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="99">
         <PDBx:B_iso_or_equiv>28.92</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>-2.014</PDBx:Cartn_x>
         <PDBx:Cartn_y>-3.652</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.859</PDBx:Cartn_z>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>ND2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>6</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>ND2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
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      <PDBx:atom_site id="100">
         <PDBx:B_iso_or_equiv>28.48</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>-5.944</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.973</PDBx:Cartn_z>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OXT</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>6</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>OXT</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="101">
         <PDBx:B_iso_or_equiv>24.35</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>-0.935</PDBx:Cartn_x>
         <PDBx:Cartn_y>-8.941</PDBx:Cartn_y>
         <PDBx:Cartn_z>1.241</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>7</PDBx:auth_seq_id>
         <PDBx:group_PDB>HETATM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_entity_id>2</PDBx:label_entity_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:occupancy>1.00</PDBx:occupancy>
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      <PDBx:atom_site id="102">
         <PDBx:B_iso_or_equiv>19.66</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>5.215</PDBx:Cartn_x>
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         <PDBx:Cartn_z>3.886</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>8</PDBx:auth_seq_id>
         <PDBx:group_PDB>HETATM</PDBx:group_PDB>
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         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_entity_id>2</PDBx:label_entity_id>
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         <PDBx:occupancy>1.00</PDBx:occupancy>
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         <PDBx:Cartn_z>1.257</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>9</PDBx:auth_seq_id>
         <PDBx:group_PDB>HETATM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_entity_id>2</PDBx:label_entity_id>
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         <PDBx:occupancy>1.00</PDBx:occupancy>
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   <PDBx:atom_sitesCategory>
      <PDBx:atom_sites entry_id="3NVE">
         <PDBx:fract_transf_matrix11>0.105119</PDBx:fract_transf_matrix11>
         <PDBx:fract_transf_matrix12>0.000000</PDBx:fract_transf_matrix12>
         <PDBx:fract_transf_matrix13>0.005592</PDBx:fract_transf_matrix13>
         <PDBx:fract_transf_matrix21>0.000000</PDBx:fract_transf_matrix21>
         <PDBx:fract_transf_matrix22>0.084861</PDBx:fract_transf_matrix22>
         <PDBx:fract_transf_matrix23>0.000000</PDBx:fract_transf_matrix23>
         <PDBx:fract_transf_matrix31>0.000000</PDBx:fract_transf_matrix31>
         <PDBx:fract_transf_matrix32>0.000000</PDBx:fract_transf_matrix32>
         <PDBx:fract_transf_matrix33>0.027405</PDBx:fract_transf_matrix33>
         <PDBx:fract_transf_vector1>0.000000</PDBx:fract_transf_vector1>
         <PDBx:fract_transf_vector2>0.000000</PDBx:fract_transf_vector2>
         <PDBx:fract_transf_vector3>0.000000</PDBx:fract_transf_vector3>
      </PDBx:atom_sites>
   </PDBx:atom_sitesCategory>
   <PDBx:atom_typeCategory>
      <PDBx:atom_type symbol="N"></PDBx:atom_type>
      <PDBx:atom_type symbol="C"></PDBx:atom_type>
      <PDBx:atom_type symbol="O"></PDBx:atom_type>
      <PDBx:atom_type symbol="S"></PDBx:atom_type>
   </PDBx:atom_typeCategory>
   <PDBx:audit_authorCategory>
      <PDBx:audit_author pdbx_ordinal="1">
         <PDBx:name>Apostol, M.I.</PDBx:name>
      </PDBx:audit_author>
      <PDBx:audit_author pdbx_ordinal="2">
         <PDBx:name>Sawaya, M.R.</PDBx:name>
      </PDBx:audit_author>
      <PDBx:audit_author pdbx_ordinal="3">
         <PDBx:name>Eisenberg, D.</PDBx:name>
      </PDBx:audit_author>
   </PDBx:audit_authorCategory>
   <PDBx:audit_conformCategory>
      <PDBx:audit_conform dict_name="mmcif_pdbx.dic" dict_version="4.007">
         <PDBx:dict_location>http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic</PDBx:dict_location>
      </PDBx:audit_conform>
   </PDBx:audit_conformCategory>
   <PDBx:cellCategory>
      <PDBx:cell entry_id="3NVE">
         <PDBx:Z_PDB>4</PDBx:Z_PDB>
         <PDBx:angle_alpha>90.000</PDBx:angle_alpha>
         <PDBx:angle_beta>93.040</PDBx:angle_beta>
         <PDBx:angle_gamma>90.000</PDBx:angle_gamma>
         <PDBx:length_a>9.513</PDBx:length_a>
         <PDBx:length_b>11.784</PDBx:length_b>
         <PDBx:length_c>36.541</PDBx:length_c>
      </PDBx:cell>
   </PDBx:cellCategory>
   <PDBx:chem_compCategory>
      <PDBx:chem_comp id="MET">
         <PDBx:formula>C5 H11 N O2 S</PDBx:formula>
         <PDBx:formula_weight>149.207</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>METHIONINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HIS">
         <PDBx:formula>C6 H10 N3 O2 1</PDBx:formula>
         <PDBx:formula_weight>156.164</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>HISTIDINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="PHE">
         <PDBx:formula>C9 H11 N O2</PDBx:formula>
         <PDBx:formula_weight>165.191</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>PHENYLALANINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLY">
         <PDBx:formula>C2 H5 N O2</PDBx:formula>
         <PDBx:formula_weight>75.067</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLYCINE</PDBx:name>
         <PDBx:type>peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ASN">
         <PDBx:formula>C4 H8 N2 O3</PDBx:formula>
         <PDBx:formula_weight>132.119</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ASPARAGINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HOH">
         <PDBx:formula>H2 O</PDBx:formula>
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>WATER</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
   </PDBx:chem_compCategory>
   <PDBx:citationCategory>
      <PDBx:citation id="primary">
         <PDBx:country>US</PDBx:country>
         <PDBx:journal_abbrev>Biochemistry</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>BICHAW</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0033</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0006-2960</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>50</PDBx:journal_volume>
         <PDBx:page_first>2456</PDBx:page_first>
         <PDBx:page_last>2463</PDBx:page_last>
         <PDBx:pdbx_database_id_DOI>10.1021/bi101803k</PDBx:pdbx_database_id_DOI>
         <PDBx:pdbx_database_id_PubMed>21323366</PDBx:pdbx_database_id_PubMed>
         <PDBx:title>Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.</PDBx:title>
         <PDBx:year>2011</PDBx:year>
      </PDBx:citation>
   </PDBx:citationCategory>
   <PDBx:citation_authorCategory>
      <PDBx:citation_author citation_id="primary" name="Apostol, M.I." ordinal="1"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Wiltzius, J.J." ordinal="2"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Sawaya, M.R." ordinal="3"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Cascio, D." ordinal="4"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Eisenberg, D." ordinal="5"></PDBx:citation_author>
   </PDBx:citation_authorCategory>
   <PDBx:computingCategory>
      <PDBx:computing entry_id="3NVE">
         <PDBx:pdbx_data_reduction_ds>SCALEPACK</PDBx:pdbx_data_reduction_ds>
         <PDBx:structure_refinement>REFMAC 5.5.0102</PDBx:structure_refinement>
         <PDBx:structure_solution>PHASER</PDBx:structure_solution>
      </PDBx:computing>
   </PDBx:computingCategory>
   <PDBx:database_2Category>
      <PDBx:database_2 database_code="3NVE" database_id="PDB"></PDBx:database_2>
      <PDBx:database_2 database_code="RCSB060326" database_id="RCSB"></PDBx:database_2>
   </PDBx:database_2Category>
   <PDBx:database_PDB_revCategory>
      <PDBx:database_PDB_rev num="1">
         <PDBx:date>2011-03-02</PDBx:date>
         <PDBx:date_original>2010-07-08</PDBx:date_original>
         <PDBx:mod_type>0</PDBx:mod_type>
         <PDBx:replaces>3NVE</PDBx:replaces>
      </PDBx:database_PDB_rev>
      <PDBx:database_PDB_rev num="2">
         <PDBx:date>2011-04-13</PDBx:date>
         <PDBx:mod_type>1</PDBx:mod_type>
         <PDBx:replaces>3NVE</PDBx:replaces>
      </PDBx:database_PDB_rev>
   </PDBx:database_PDB_revCategory>
   <PDBx:database_PDB_rev_recordCategory>
      <PDBx:database_PDB_rev_record rev_num="2" type="JRNL">
      </PDBx:database_PDB_rev_record>
   </PDBx:database_PDB_rev_recordCategory>
   <PDBx:diffrnCategory>
      <PDBx:diffrn id="1">
         <PDBx:ambient_temp>100</PDBx:ambient_temp>
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
      <PDBx:diffrn id="2">
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
      <PDBx:diffrn id="3">
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
      <PDBx:diffrn id="4">
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
      <PDBx:diffrn id="5">
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
      <PDBx:diffrn id="6">
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
      <PDBx:diffrn id="7">
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
      <PDBx:diffrn id="8">
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
      <PDBx:diffrn id="9">
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
      <PDBx:diffrn id="10">
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
   </PDBx:diffrnCategory>
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      <PDBx:diffrn_detector diffrn_id="1">
         <PDBx:detector>IMAGE PLATE</PDBx:detector>
         <PDBx:pdbx_collection_date>2008-01-01</PDBx:pdbx_collection_date>
         <PDBx:type>RIGAKU RAXIS IV++</PDBx:type>
      </PDBx:diffrn_detector>
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      <PDBx:diffrn_radiation diffrn_id="1">
         <PDBx:pdbx_diffrn_protocol>SINGLE WAVELENGTH</PDBx:pdbx_diffrn_protocol>
         <PDBx:pdbx_monochromatic_or_laue_m_l>M</PDBx:pdbx_monochromatic_or_laue_m_l>
         <PDBx:pdbx_scattering_type>x-ray</PDBx:pdbx_scattering_type>
         <PDBx:wavelength_id>1</PDBx:wavelength_id>
      </PDBx:diffrn_radiation>
   </PDBx:diffrn_radiationCategory>
   <PDBx:diffrn_radiation_wavelengthCategory>
      <PDBx:diffrn_radiation_wavelength id="1">
         <PDBx:wavelength>1.5418</PDBx:wavelength>
         <PDBx:wt>1.0</PDBx:wt>
      </PDBx:diffrn_radiation_wavelength>
   </PDBx:diffrn_radiation_wavelengthCategory>
   <PDBx:diffrn_sourceCategory>
      <PDBx:diffrn_source diffrn_id="1">
         <PDBx:pdbx_wavelength_list>1.5418</PDBx:pdbx_wavelength_list>
         <PDBx:source>ROTATING ANODE</PDBx:source>
         <PDBx:type>RIGAKU FR-D GENERATOR</PDBx:type>
      </PDBx:diffrn_source>
   </PDBx:diffrn_sourceCategory>
   <PDBx:entityCategory>
      <PDBx:entity id="1">
         <PDBx:formula_weight>736.880</PDBx:formula_weight>
         <PDBx:pdbx_description>Major prion protein</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>2</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>polymer</PDBx:type>
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         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:pdbx_description>water</PDBx:pdbx_description>
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         <PDBx:src_method>nat</PDBx:src_method>
         <PDBx:type>water</PDBx:type>
      </PDBx:entity>
   </PDBx:entityCategory>
   <PDBx:entity_name_comCategory>
      <PDBx:entity_name_com entity_id="1">
         <PDBx:name>PrP, PrP27-30, PrP33-35C</PDBx:name>
      </PDBx:entity_name_com>
      <PDBx:entity_name_com entity_id="2">
      </PDBx:entity_name_com>
   </PDBx:entity_name_comCategory>
   <PDBx:entity_polyCategory>
      <PDBx:entity_poly entity_id="1">
         <PDBx:nstd_linkage>no</PDBx:nstd_linkage>
         <PDBx:nstd_monomer>no</PDBx:nstd_monomer>
         <PDBx:pdbx_seq_one_letter_code>MMHFGN</PDBx:pdbx_seq_one_letter_code>
         <PDBx:pdbx_seq_one_letter_code_can>MMHFGN</PDBx:pdbx_seq_one_letter_code_can>
         <PDBx:pdbx_strand_id>A,B</PDBx:pdbx_strand_id>
         <PDBx:type>polypeptide(L)</PDBx:type>
      </PDBx:entity_poly>
   </PDBx:entity_polyCategory>
   <PDBx:entity_poly_seqCategory>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="1">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="2">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="3">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="4">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="5">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="6">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
   </PDBx:entity_poly_seqCategory>
   <PDBx:entryCategory>
      <PDBx:entry id="3NVE"></PDBx:entry>
   </PDBx:entryCategory>
   <PDBx:exptlCategory>
      <PDBx:exptl entry_id="3NVE" method="X-RAY DIFFRACTION">
         <PDBx:crystals_number>1</PDBx:crystals_number>
      </PDBx:exptl>
   </PDBx:exptlCategory>
   <PDBx:exptl_crystalCategory>
      <PDBx:exptl_crystal id="1">
         <PDBx:density_Matthews>1.39</PDBx:density_Matthews>
         <PDBx:density_percent_sol>11.37</PDBx:density_percent_sol>
      </PDBx:exptl_crystal>
   </PDBx:exptl_crystalCategory>
   <PDBx:exptl_crystal_growCategory>
      <PDBx:exptl_crystal_grow crystal_id="1">
         <PDBx:method>vapor diffusion, hanging drop</PDBx:method>
         <PDBx:pH>7.5</PDBx:pH>
         <PDBx:pdbx_details>1.2 M Ammonium sulfate, 200 mM BisTris pH 7.5, vapor diffusion, hanging drop, temperature 298K</PDBx:pdbx_details>
         <PDBx:temp>298</PDBx:temp>
      </PDBx:exptl_crystal_grow>
   </PDBx:exptl_crystal_growCategory>
   <PDBx:pdbx_database_relatedCategory>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="3NVF" db_name="PDB">
         <PDBx:details>IIHFGS hexapeptide (residues 138-143) from human prion protein</PDBx:details>
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="3NVG" db_name="PDB">
         <PDBx:details>MIHFGN hexapeptide (residues 137-142) from mouse prion protein</PDBx:details>
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="3NVH" db_name="PDB">
         <PDBx:details>MIHFGND (residues 137-143) from mouse prion protein</PDBx:details>
      </PDBx:pdbx_database_related>
   </PDBx:pdbx_database_relatedCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="3NVE">
         <PDBx:deposit_site>RCSB</PDBx:deposit_site>
         <PDBx:process_site>RCSB</PDBx:process_site>
         <PDBx:status_code>REL</PDBx:status_code>
         <PDBx:status_code_sf>REL</PDBx:status_code_sf>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="2">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_entity_src_synCategory>
      <PDBx:pdbx_entity_src_syn entity_id="1">
         <PDBx:details>MMHFGN (UNP residues 138-143) from Syrian hamster prion</PDBx:details>
         <PDBx:ncbi_taxonomy_id>10036</PDBx:ncbi_taxonomy_id>
         <PDBx:organism_common_name>Golden hamster</PDBx:organism_common_name>
         <PDBx:organism_scientific>Mesocricetus auratus</PDBx:organism_scientific>
      </PDBx:pdbx_entity_src_syn>
   </PDBx:pdbx_entity_src_synCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>7</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>8</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>9</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_phasing_MRCategory>
      <PDBx:pdbx_phasing_MR entry_id="3NVE">
         <PDBx:d_res_high_rotation>1.730</PDBx:d_res_high_rotation>
         <PDBx:d_res_high_translation>1.730</PDBx:d_res_high_translation>
         <PDBx:d_res_low_rotation>18.240</PDBx:d_res_low_rotation>
         <PDBx:d_res_low_translation>18.240</PDBx:d_res_low_translation>
         <PDBx:model_details>Phaser MODE: MR_AUTO</PDBx:model_details>
      </PDBx:pdbx_phasing_MR>
   </PDBx:pdbx_phasing_MRCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="1">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="2">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="3">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="4">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="5">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>5</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="6">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>6</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="1">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="2">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="3">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PHE" seq_id="4">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="5">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>5</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASN" seq_id="6">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>6</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_prerelease_seqCategory>
      <PDBx:pdbx_prerelease_seq entity_id="1">
         <PDBx:seq_one_letter_code>MMHFGN</PDBx:seq_one_letter_code>
      </PDBx:pdbx_prerelease_seq>
   </PDBx:pdbx_prerelease_seqCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_defined_assembly</PDBx:details>
         <PDBx:oligomeric_count>12</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>dodecameric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,C,B" oper_expression="1,2,3,4,5,6"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_assembly_propCategory>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="ABSA (A^2)">
         <PDBx:value>430</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="SSA (A^2)">
         <PDBx:value>1550</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="MORE">
         <PDBx:value>-2</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
   </PDBx:pdbx_struct_assembly_propCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:symmetry_operation>x,y,z</PDBx:symmetry_operation>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="2">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_655</PDBx:name>
         <PDBx:symmetry_operation>x+1,y,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>9.5130000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="3">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_455</PDBx:name>
         <PDBx:symmetry_operation>x-1,y,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>-9.5130000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="4">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_565</PDBx:name>
         <PDBx:symmetry_operation>x,y+1,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>11.7840000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="5">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_665</PDBx:name>
         <PDBx:symmetry_operation>x+1,y+1,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>9.5130000000</PDBx:vector1>
         <PDBx:vector2>11.7840000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="6">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_465</PDBx:name>
         <PDBx:symmetry_operation>x-1,y+1,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>-9.5130000000</PDBx:vector1>
         <PDBx:vector2>11.7840000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_struct_sheet_hbondCategory>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="A">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>HIS</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>3</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>HIS</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>3</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>B</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>HIS</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>3</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>B</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>HIS</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>3</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
   </PDBx:pdbx_struct_sheet_hbondCategory>
   <PDBx:pdbx_versionCategory>
      <PDBx:pdbx_version entry_id="3NVE" major_version="3" minor_version="2" revision_type="Version format compliance">
         <PDBx:details>compliance with PDB format V.3.20</PDBx:details>
         <PDBx:revision_date>2010-07-13</PDBx:revision_date>
      </PDBx:pdbx_version>
      <PDBx:pdbx_version entry_id="3NVE" major_version="4" minor_version="0000" revision_type="Version format compliance">
         <PDBx:details>compliance with PDB Exchange Dictionary V4</PDBx:details>
         <PDBx:revision_date>2011-07-13</PDBx:revision_date>
      </PDBx:pdbx_version>
   </PDBx:pdbx_versionCategory>
   <PDBx:phasingCategory>
      <PDBx:phasing method="MR"></PDBx:phasing>
   </PDBx:phasingCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="3NVE" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:B_iso_max>39.510</PDBx:B_iso_max>
         <PDBx:B_iso_mean>20.7686</PDBx:B_iso_mean>
         <PDBx:B_iso_min>14.480</PDBx:B_iso_min>
         <PDBx:aniso_B11>0.2500</PDBx:aniso_B11>
         <PDBx:aniso_B12>0.0000</PDBx:aniso_B12>
         <PDBx:aniso_B13>-0.1200</PDBx:aniso_B13>
         <PDBx:aniso_B22>-0.1100</PDBx:aniso_B22>
         <PDBx:aniso_B23>0.0000</PDBx:aniso_B23>
         <PDBx:aniso_B33>-0.1500</PDBx:aniso_B33>
         <PDBx:correlation_coeff_Fo_to_Fc>0.9640</PDBx:correlation_coeff_Fo_to_Fc>
         <PDBx:correlation_coeff_Fo_to_Fc_free>0.9610</PDBx:correlation_coeff_Fo_to_Fc_free>
         <PDBx:details>HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES      : REFINED INDIVIDUALLY</PDBx:details>
         <PDBx:ls_R_factor_R_free>0.2688</PDBx:ls_R_factor_R_free>
         <PDBx:ls_R_factor_R_work>0.1958</PDBx:ls_R_factor_R_work>
         <PDBx:ls_R_factor_obs>0.2060</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>1.7000</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>36.4900</PDBx:ls_d_res_low>
         <PDBx:ls_number_reflns_R_free>139</PDBx:ls_number_reflns_R_free>
         <PDBx:ls_number_reflns_obs>935</PDBx:ls_number_reflns_obs>
         <PDBx:ls_percent_reflns_R_free>14.9000</PDBx:ls_percent_reflns_R_free>
         <PDBx:ls_percent_reflns_obs>97.0900</PDBx:ls_percent_reflns_obs>
         <PDBx:ls_wR_factor_R_free>0.3382</PDBx:ls_wR_factor_R_free>
         <PDBx:ls_wR_factor_R_work>0.2260</PDBx:ls_wR_factor_R_work>
         <PDBx:occupancy_max>1.000</PDBx:occupancy_max>
         <PDBx:occupancy_min>1.000</PDBx:occupancy_min>
         <PDBx:overall_FOM_work_R_set>0.7689</PDBx:overall_FOM_work_R_set>
         <PDBx:overall_SU_B>3.6920</PDBx:overall_SU_B>
         <PDBx:overall_SU_ML>0.1110</PDBx:overall_SU_ML>
         <PDBx:overall_SU_R_Cruickshank_DPI>0.1837</PDBx:overall_SU_R_Cruickshank_DPI>
         <PDBx:overall_SU_R_free>0.1752</PDBx:overall_SU_R_free>
         <PDBx:pdbx_R_Free_selection_details>RANDOM</PDBx:pdbx_R_Free_selection_details>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_ls_cross_valid_method>THROUGHOUT</PDBx:pdbx_ls_cross_valid_method>
         <PDBx:pdbx_ls_sigma_F>0.000</PDBx:pdbx_ls_sigma_F>
         <PDBx:pdbx_method_to_determine_struct>MOLECULAR REPLACEMENT</PDBx:pdbx_method_to_determine_struct>
         <PDBx:pdbx_overall_ESU_R_Free>0.1750</PDBx:pdbx_overall_ESU_R_Free>
         <PDBx:pdbx_solvent_ion_probe_radii>0.8000</PDBx:pdbx_solvent_ion_probe_radii>
         <PDBx:pdbx_solvent_shrinkage_radii>0.8000</PDBx:pdbx_solvent_shrinkage_radii>
         <PDBx:pdbx_solvent_vdw_probe_radii>1.4000</PDBx:pdbx_solvent_vdw_probe_radii>
         <PDBx:pdbx_stereochemistry_target_values>MAXIMUM LIKELIHOOD</PDBx:pdbx_stereochemistry_target_values>
         <PDBx:solvent_model_details>MASK</PDBx:solvent_model_details>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="LAST" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>1.7000</PDBx:d_res_high>
         <PDBx:d_res_low>36.4900</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>3</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>103</PDBx:number_atoms_total>
         <PDBx:pdbx_number_atoms_ligand>0</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>0</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>100</PDBx:pdbx_number_atoms_protein>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_bond_refined_d">
         <PDBx:dev_ideal>0.024</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>102</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_bond_other_d">
         <PDBx:dev_ideal>0.001</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>66</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_angle_refined_deg">
         <PDBx:dev_ideal>1.904</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>1.871</PDBx:dev_ideal_target>
         <PDBx:number>132</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_angle_other_deg">
         <PDBx:dev_ideal>0.948</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>3.000</PDBx:dev_ideal_target>
         <PDBx:number>158</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_1_deg">
         <PDBx:dev_ideal>5.404</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>5.000</PDBx:dev_ideal_target>
         <PDBx:number>10</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_2_deg">
         <PDBx:dev_ideal>41.636</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>23.333</PDBx:dev_ideal_target>
         <PDBx:number>6</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_3_deg">
         <PDBx:dev_ideal>13.371</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>15.000</PDBx:dev_ideal_target>
         <PDBx:number>18</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_chiral_restr">
         <PDBx:dev_ideal>0.085</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>10</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_gen_planes_refined">
         <PDBx:dev_ideal>0.006</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>112</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_gen_planes_other">
         <PDBx:dev_ideal>0.001</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>24</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcbond_it">
         <PDBx:dev_ideal>1.100</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>1.500</PDBx:dev_ideal_target>
         <PDBx:number>58</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcbond_other">
         <PDBx:dev_ideal>0.290</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>1.500</PDBx:dev_ideal_target>
         <PDBx:number>24</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcangle_it">
         <PDBx:dev_ideal>2.024</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>2.000</PDBx:dev_ideal_target>
         <PDBx:number>88</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_scbond_it">
         <PDBx:dev_ideal>3.550</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>3.000</PDBx:dev_ideal_target>
         <PDBx:number>44</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_scangle_it">
         <PDBx:dev_ideal>4.721</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>4.500</PDBx:dev_ideal_target>
         <PDBx:number>44</PDBx:number>
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:refine_ls_shellCategory>
      <PDBx:refine_ls_shell d_res_high="1.7010" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.6010</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_work>0.2910</PDBx:R_factor_R_work>
         <PDBx:d_res_low>1.7450</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>9</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>45</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>54</PDBx:number_reflns_all>
         <PDBx:pdbx_total_number_of_bins_used>20</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_obs>85.7100</PDBx:percent_reflns_obs>
      </PDBx:refine_ls_shell>
   </PDBx:refine_ls_shellCategory>
   <PDBx:reflnsCategory>
      <PDBx:reflns pdbx_ordinal="1">
         <PDBx:d_resolution_high>1.700</PDBx:d_resolution_high>
         <PDBx:d_resolution_low>80.000</PDBx:d_resolution_low>
         <PDBx:entry_id>3NVE</PDBx:entry_id>
         <PDBx:number_obs>939</PDBx:number_obs>
         <PDBx:pdbx_Rmerge_I_obs>0.162</PDBx:pdbx_Rmerge_I_obs>
         <PDBx:pdbx_chi_squared>1.021</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_netI_over_sigmaI>15.900</PDBx:pdbx_netI_over_sigmaI>
         <PDBx:pdbx_redundancy>10.500</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_obs>97.200</PDBx:percent_possible_obs>
      </PDBx:reflns>
   </PDBx:reflnsCategory>
   <PDBx:reflns_shellCategory>
      <PDBx:reflns_shell pdbx_ordinal="1">
         <PDBx:Rmerge_I_obs>0.150</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.700</PDBx:d_res_high>
         <PDBx:d_res_low>1.760</PDBx:d_res_low>
         <PDBx:number_unique_all>73</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.995</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>5.800</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>88.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="2">
         <PDBx:Rmerge_I_obs>0.205</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.760</PDBx:d_res_high>
         <PDBx:d_res_low>1.830</PDBx:d_res_low>
         <PDBx:number_unique_all>101</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.010</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>2</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>8.800</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>99.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="3">
         <PDBx:Rmerge_I_obs>0.156</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.830</PDBx:d_res_high>
         <PDBx:d_res_low>1.910</PDBx:d_res_low>
         <PDBx:number_unique_all>94</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.986</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>3</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>10.600</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>91.300</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="4">
         <PDBx:Rmerge_I_obs>0.143</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.910</PDBx:d_res_high>
         <PDBx:d_res_low>2.020</PDBx:d_res_low>
         <PDBx:number_unique_all>82</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.987</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>4</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>11.300</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>98.800</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="5">
         <PDBx:Rmerge_I_obs>0.157</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.020</PDBx:d_res_high>
         <PDBx:d_res_low>2.140</PDBx:d_res_low>
         <PDBx:number_unique_all>94</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.044</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>5</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>11.700</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="6">
         <PDBx:Rmerge_I_obs>0.149</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.140</PDBx:d_res_high>
         <PDBx:d_res_low>2.310</PDBx:d_res_low>
         <PDBx:number_unique_all>99</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.001</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>6</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>11.500</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="7">
         <PDBx:Rmerge_I_obs>0.159</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.310</PDBx:d_res_high>
         <PDBx:d_res_low>2.540</PDBx:d_res_low>
         <PDBx:number_unique_all>93</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.060</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>7</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>11.400</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>95.900</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="8">
         <PDBx:Rmerge_I_obs>0.149</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.540</PDBx:d_res_high>
         <PDBx:d_res_low>2.910</PDBx:d_res_low>
         <PDBx:number_unique_all>93</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.998</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>8</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>11.400</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>98.900</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="9">
         <PDBx:Rmerge_I_obs>0.167</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.911</PDBx:d_res_high>
         <PDBx:d_res_low>3.660</PDBx:d_res_low>
         <PDBx:number_unique_all>105</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.093</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>9</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>11.200</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="10">
         <PDBx:Rmerge_I_obs>0.163</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>3.662</PDBx:d_res_high>
         <PDBx:d_res_low>80.000</PDBx:d_res_low>
         <PDBx:number_unique_all>105</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.000</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>10</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>10.700</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>99.100</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
   </PDBx:reflns_shellCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>data scaling</PDBx:classification>
         <PDBx:contact_author>Zbyszek Otwinowski</PDBx:contact_author>
         <PDBx:contact_author_email>hkl@hkl-xray.com</PDBx:contact_author_email>
         <PDBx:location>http://www.hkl-xray.com/</PDBx:location>
         <PDBx:name>SCALEPACK</PDBx:name>
         <PDBx:type>program</PDBx:type>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="2">
         <PDBx:classification>molecular replacement</PDBx:classification>
         <PDBx:contact_author>Randy J. Read</PDBx:contact_author>
         <PDBx:contact_author_email>cimr-phaser@lists.cam.ac.uk</PDBx:contact_author_email>
         <PDBx:date>Sun Mar 23 21:15:16 2008</PDBx:date>
         <PDBx:location>http://www-structmed.cimr.cam.ac.uk/phaser/</PDBx:location>
         <PDBx:name>Phaser</PDBx:name>
         <PDBx:type>program</PDBx:type>
         <PDBx:version>1.3.3</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="3">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:contact_author>Garib N. Murshudov</PDBx:contact_author>
         <PDBx:contact_author_email>garib@ysbl.york.ac.uk</PDBx:contact_author_email>
         <PDBx:language>Fortran_77</PDBx:language>
         <PDBx:location>http://www.ccp4.ac.uk/dist/html/refmac5.html</PDBx:location>
         <PDBx:name>REFMAC5</PDBx:name>
         <PDBx:type>program</PDBx:type>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="4">
         <PDBx:classification>data extraction</PDBx:classification>
         <PDBx:contact_author>PDB</PDBx:contact_author>
         <PDBx:contact_author_email>deposit@deposit.rcsb.org</PDBx:contact_author_email>
         <PDBx:date>June 10, 2010</PDBx:date>
         <PDBx:language>C++</PDBx:language>
         <PDBx:location>http://sw-tools.pdb.org/apps/PDB_EXTRACT/</PDBx:location>
         <PDBx:name>pdb_extract</PDBx:name>
         <PDBx:type>package</PDBx:type>
         <PDBx:version>3.10</PDBx:version>
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="3NVE">
         <PDBx:pdbx_descriptor>Major prion protein</PDBx:pdbx_descriptor>
         <PDBx:title>MMHFGN segment 138-143 from Syrian Hamster prion</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="C">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_biolCategory>
      <PDBx:struct_biol id="1">
      </PDBx:struct_biol>
   </PDBx:struct_biolCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="3NVE">
         <PDBx:pdbx_keywords>PROTEIN FIBRIL</PDBx:pdbx_keywords>
         <PDBx:text>amyloid-like protofibril, PROTEIN FIBRIL</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:biol_id xsi:nil="true" />
         <PDBx:db_code>PRIO_MESAU</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>138</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>P04273</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>MMHFGN</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>138</PDBx:db_align_beg>
         <PDBx:db_align_end>143</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>3NVE</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>1</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>6</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P04273</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>6</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
      <PDBx:struct_ref_seq align_id="2">
         <PDBx:db_align_beg>138</PDBx:db_align_beg>
         <PDBx:db_align_end>143</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>3NVE</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>1</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>6</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P04273</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>B</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>6</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_sheetCategory>
      <PDBx:struct_sheet id="A">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
   </PDBx:struct_sheetCategory>
   <PDBx:struct_sheet_orderCategory>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
   </PDBx:struct_sheet_orderCategory>
   <PDBx:struct_sheet_rangeCategory>
      <PDBx:struct_sheet_range id="1" sheet_id="A">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>MET</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>2</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>MET</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>2</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>PHE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>4</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>PHE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>4</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="A">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>MET</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>2</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>MET</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>2</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>PHE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>4</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>PHE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>4</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
   </PDBx:struct_sheet_rangeCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="3NVE">
         <PDBx:Int_Tables_number>4</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>P 1 21 1</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
