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      </PDBx:citation>
   </PDBx:citationCategory>
   <PDBx:citation_authorCategory>
      <PDBx:citation_author citation_id="primary" name="Rodriguez, J.A." ordinal="1"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Ivanova, M.I." ordinal="2"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Sawaya, M.R." ordinal="3"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Cascio, D." ordinal="4"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Reyes, F.E." ordinal="5"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Shi, D." ordinal="6"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Sangwan, S." ordinal="7"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Guenther, E.L." ordinal="8"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Johnson, L.M." ordinal="9"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Zhang, M." ordinal="10"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Jiang, L." ordinal="11"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Arbing, M.A." ordinal="12"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Nannenga, B.L." ordinal="13"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Hattne, J." ordinal="14"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Whitelegge, J." ordinal="15"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Brewster, A.S." ordinal="16"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Messerschmidt, M." ordinal="17"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Boutet, S." ordinal="18"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Sauter, N.K." ordinal="19"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Gonen, T." ordinal="20"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Eisenberg, D.S." ordinal="21"></PDBx:citation_author>
   </PDBx:citation_authorCategory>
   <PDBx:computingCategory>
      <PDBx:computing entry_id="4RIK">
         <PDBx:pdbx_data_reduction_ds>SCALEPACK</PDBx:pdbx_data_reduction_ds>
         <PDBx:pdbx_data_reduction_ii>DENZO</PDBx:pdbx_data_reduction_ii>
         <PDBx:structure_refinement>REFMAC 5.0</PDBx:structure_refinement>
         <PDBx:structure_solution>PHASER</PDBx:structure_solution>
      </PDBx:computing>
   </PDBx:computingCategory>
   <PDBx:database_2Category>
      <PDBx:database_2 database_code="4RIK" database_id="PDB"></PDBx:database_2>
      <PDBx:database_2 database_code="RCSB087389" database_id="RCSB"></PDBx:database_2>
   </PDBx:database_2Category>
   <PDBx:database_PDB_revCategory>
      <PDBx:database_PDB_rev num="1">
         <PDBx:date>2015-08-26</PDBx:date>
         <PDBx:date_original>2014-10-06</PDBx:date_original>
         <PDBx:mod_type>0</PDBx:mod_type>
         <PDBx:replaces>4RIK</PDBx:replaces>
      </PDBx:database_PDB_rev>
      <PDBx:database_PDB_rev num="2">
         <PDBx:date>2015-09-09</PDBx:date>
         <PDBx:mod_type>1</PDBx:mod_type>
         <PDBx:replaces>4RIK</PDBx:replaces>
      </PDBx:database_PDB_rev>
      <PDBx:database_PDB_rev num="3">
         <PDBx:date>2015-09-23</PDBx:date>
         <PDBx:mod_type>1</PDBx:mod_type>
         <PDBx:replaces>4RIK</PDBx:replaces>
      </PDBx:database_PDB_rev>
      <PDBx:database_PDB_rev num="4">
         <PDBx:date>2015-10-07</PDBx:date>
         <PDBx:mod_type>1</PDBx:mod_type>
         <PDBx:replaces>4RIK</PDBx:replaces>
      </PDBx:database_PDB_rev>
   </PDBx:database_PDB_revCategory>
   <PDBx:database_PDB_rev_recordCategory>
      <PDBx:database_PDB_rev_record rev_num="2" type="JRNL">
      </PDBx:database_PDB_rev_record>
      <PDBx:database_PDB_rev_record rev_num="3" type="JRNL">
      </PDBx:database_PDB_rev_record>
      <PDBx:database_PDB_rev_record rev_num="4" type="JRNL">
      </PDBx:database_PDB_rev_record>
   </PDBx:database_PDB_rev_recordCategory>
   <PDBx:diffrnCategory>
      <PDBx:diffrn id="1">
         <PDBx:ambient_temp>100</PDBx:ambient_temp>
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
   </PDBx:diffrnCategory>
   <PDBx:diffrn_detectorCategory>
      <PDBx:diffrn_detector diffrn_id="1">
         <PDBx:detector>CCD</PDBx:detector>
         <PDBx:pdbx_collection_date>2011-08-23</PDBx:pdbx_collection_date>
         <PDBx:type>ADSC QUANTUM 315</PDBx:type>
      </PDBx:diffrn_detector>
   </PDBx:diffrn_detectorCategory>
   <PDBx:diffrn_radiationCategory>
      <PDBx:diffrn_radiation diffrn_id="1">
         <PDBx:pdbx_diffrn_protocol>SINGLE WAVELENGTH</PDBx:pdbx_diffrn_protocol>
         <PDBx:pdbx_monochromatic_or_laue_m_l>M</PDBx:pdbx_monochromatic_or_laue_m_l>
         <PDBx:pdbx_scattering_type>x-ray</PDBx:pdbx_scattering_type>
         <PDBx:wavelength_id>1</PDBx:wavelength_id>
      </PDBx:diffrn_radiation>
   </PDBx:diffrn_radiationCategory>
   <PDBx:diffrn_radiation_wavelengthCategory>
      <PDBx:diffrn_radiation_wavelength id="1">
         <PDBx:wavelength>0.9791</PDBx:wavelength>
         <PDBx:wt>1.0</PDBx:wt>
      </PDBx:diffrn_radiation_wavelength>
   </PDBx:diffrn_radiation_wavelengthCategory>
   <PDBx:diffrn_sourceCategory>
      <PDBx:diffrn_source diffrn_id="1">
         <PDBx:pdbx_synchrotron_beamline>24-ID-E</PDBx:pdbx_synchrotron_beamline>
         <PDBx:pdbx_synchrotron_site>APS</PDBx:pdbx_synchrotron_site>
         <PDBx:pdbx_wavelength_list>0.9791</PDBx:pdbx_wavelength_list>
         <PDBx:source>SYNCHROTRON</PDBx:source>
         <PDBx:type>APS BEAMLINE 24-ID-E</PDBx:type>
      </PDBx:diffrn_source>
   </PDBx:diffrn_sourceCategory>
   <PDBx:entityCategory>
      <PDBx:entity id="1">
         <PDBx:formula_weight>815.963</PDBx:formula_weight>
         <PDBx:pdbx_description>Alpha-synuclein</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="2">
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:pdbx_description>water</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>3</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>nat</PDBx:src_method>
         <PDBx:type>water</PDBx:type>
      </PDBx:entity>
   </PDBx:entityCategory>
   <PDBx:entity_name_comCategory>
      <PDBx:entity_name_com entity_id="1">
         <PDBx:name>Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP</PDBx:name>
      </PDBx:entity_name_com>
      <PDBx:entity_name_com entity_id="2">
      </PDBx:entity_name_com>
   </PDBx:entity_name_comCategory>
   <PDBx:entity_polyCategory>
      <PDBx:entity_poly entity_id="1">
         <PDBx:nstd_linkage>no</PDBx:nstd_linkage>
         <PDBx:nstd_monomer>no</PDBx:nstd_monomer>
         <PDBx:pdbx_seq_one_letter_code>AVVTGVTAV</PDBx:pdbx_seq_one_letter_code>
         <PDBx:pdbx_seq_one_letter_code_can>AVVTGVTAV</PDBx:pdbx_seq_one_letter_code_can>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:type>polypeptide(L)</PDBx:type>
      </PDBx:entity_poly>
   </PDBx:entity_polyCategory>
   <PDBx:entity_poly_seqCategory>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="1">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="2">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="3">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="4">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="5">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="6">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="7">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="8">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="9">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
   </PDBx:entity_poly_seqCategory>
   <PDBx:entryCategory>
      <PDBx:entry id="4RIK"></PDBx:entry>
   </PDBx:entryCategory>
   <PDBx:exptlCategory>
      <PDBx:exptl entry_id="4RIK" method="X-RAY DIFFRACTION">
         <PDBx:crystals_number>1</PDBx:crystals_number>
      </PDBx:exptl>
   </PDBx:exptlCategory>
   <PDBx:exptl_crystalCategory>
      <PDBx:exptl_crystal id="1">
         <PDBx:density_Matthews>1.52</PDBx:density_Matthews>
         <PDBx:density_percent_sol>19.22</PDBx:density_percent_sol>
      </PDBx:exptl_crystal>
   </PDBx:exptl_crystalCategory>
   <PDBx:exptl_crystal_growCategory>
      <PDBx:exptl_crystal_grow crystal_id="1">
         <PDBx:method>vapor diffusion, hanging drop</PDBx:method>
         <PDBx:pH>4.6</PDBx:pH>
         <PDBx:pdbx_details>0.9M Ammonium Phosphate, 0.1M Sodium Acetate, pH 4.6, vapor diffusion, hanging drop, temperature 273K</PDBx:pdbx_details>
         <PDBx:temp>273</PDBx:temp>
      </PDBx:exptl_crystal_grow>
   </PDBx:exptl_crystal_growCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="4RIK">
         <PDBx:deposit_site>RCSB</PDBx:deposit_site>
         <PDBx:process_site>RCSB</PDBx:process_site>
         <PDBx:status_code>REL</PDBx:status_code>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="2">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_entity_src_synCategory>
      <PDBx:pdbx_entity_src_syn entity_id="1">
         <PDBx:details>Synthetic peptide AVVTGVTAV corresponding to segment 69-77 of human alpha-synuclein</PDBx:details>
         <PDBx:ncbi_taxonomy_id>9606</PDBx:ncbi_taxonomy_id>
         <PDBx:organism_common_name>human</PDBx:organism_common_name>
         <PDBx:organism_scientific>Homo sapiens</PDBx:organism_scientific>
      </PDBx:pdbx_entity_src_syn>
   </PDBx:pdbx_entity_src_synCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>11</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>101</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>12</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>102</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>13</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>103</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_phasing_MRCategory>
      <PDBx:pdbx_phasing_MR entry_id="4RIK">
         <PDBx:model_details>Phaser MODE: MR_AUTO</PDBx:model_details>
      </PDBx:pdbx_phasing_MR>
   </PDBx:pdbx_phasing_MRCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="1">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>69</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="2">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>70</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="3">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>71</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="4">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>72</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="5">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>73</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="6">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>74</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="7">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>7</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>75</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="8">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>8</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>76</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="9">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>9</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>77</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_defined_assembly</PDBx:details>
         <PDBx:oligomeric_count>10</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>decameric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="1,2,3,4,5,6,7,8,9,10"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:symmetry_operation>x,y,z</PDBx:symmetry_operation>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="2">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_535</PDBx:name>
         <PDBx:symmetry_operation>x,y-2,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>-9.5980000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="3">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_545</PDBx:name>
         <PDBx:symmetry_operation>x,y-1,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>-4.7990000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="4">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_565</PDBx:name>
         <PDBx:symmetry_operation>x,y+1,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>4.7990000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="5">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_575</PDBx:name>
         <PDBx:symmetry_operation>x,y+2,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>9.5980000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="6">
         <PDBx:matrix11>-1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_535</PDBx:name>
         <PDBx:symmetry_operation>-x+1/2,y-3/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>30.9320000000</PDBx:vector1>
         <PDBx:vector2>-7.1985000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="7">
         <PDBx:matrix11>-1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_545</PDBx:name>
         <PDBx:symmetry_operation>-x+1/2,y-1/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>30.9320000000</PDBx:vector1>
         <PDBx:vector2>-2.3995000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="8">
         <PDBx:matrix11>-1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_555</PDBx:name>
         <PDBx:symmetry_operation>-x+1/2,y+1/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>30.9320000000</PDBx:vector1>
         <PDBx:vector2>2.3995000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="9">
         <PDBx:matrix11>-1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_565</PDBx:name>
         <PDBx:symmetry_operation>-x+1/2,y+3/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>30.9320000000</PDBx:vector1>
         <PDBx:vector2>7.1985000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="10">
         <PDBx:matrix11>-1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_575</PDBx:name>
         <PDBx:symmetry_operation>-x+1/2,y+5/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>30.9320000000</PDBx:vector1>
         <PDBx:vector2>11.9975000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_versionCategory>
      <PDBx:pdbx_version entry_id="4RIK" major_version="4" minor_version="0000" revision_type="Initial release">
         <PDBx:details>Initial release</PDBx:details>
         <PDBx:revision_date>2015-08-26</PDBx:revision_date>
      </PDBx:pdbx_version>
      <PDBx:pdbx_version entry_id="4RIK" major_version="4" minor_version="0001" revision_type="Citation">
         <PDBx:details>Citation update</PDBx:details>
         <PDBx:revision_date>2015-09-09</PDBx:revision_date>
      </PDBx:pdbx_version>
      <PDBx:pdbx_version entry_id="4RIK" major_version="4" minor_version="0002" revision_type="Citation">
         <PDBx:details>Citation update</PDBx:details>
         <PDBx:revision_date>2015-09-23</PDBx:revision_date>
      </PDBx:pdbx_version>
      <PDBx:pdbx_version entry_id="4RIK" major_version="4" minor_version="0003" revision_type="Citation">
         <PDBx:details>Citation update</PDBx:details>
         <PDBx:revision_date>2015-10-07</PDBx:revision_date>
      </PDBx:pdbx_version>
   </PDBx:pdbx_versionCategory>
   <PDBx:phasingCategory>
      <PDBx:phasing method="MR"></PDBx:phasing>
   </PDBx:phasingCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="4RIK" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:B_iso_max>53.100</PDBx:B_iso_max>
         <PDBx:B_iso_mean>17.3410</PDBx:B_iso_mean>
         <PDBx:B_iso_min>6.250</PDBx:B_iso_min>
         <PDBx:aniso_B11>-0.2300</PDBx:aniso_B11>
         <PDBx:aniso_B12>-0.0000</PDBx:aniso_B12>
         <PDBx:aniso_B13>-0.0600</PDBx:aniso_B13>
         <PDBx:aniso_B22>-0.0200</PDBx:aniso_B22>
         <PDBx:aniso_B23>-0.0000</PDBx:aniso_B23>
         <PDBx:aniso_B33>0.2500</PDBx:aniso_B33>
         <PDBx:correlation_coeff_Fo_to_Fc>0.9780</PDBx:correlation_coeff_Fo_to_Fc>
         <PDBx:correlation_coeff_Fo_to_Fc_free>0.9610</PDBx:correlation_coeff_Fo_to_Fc_free>
         <PDBx:details>HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES      : REFINED INDIVIDUALLY</PDBx:details>
         <PDBx:ls_R_factor_R_free>0.2211</PDBx:ls_R_factor_R_free>
         <PDBx:ls_R_factor_R_work>0.1758</PDBx:ls_R_factor_R_work>
         <PDBx:ls_R_factor_all>0.1802</PDBx:ls_R_factor_all>
         <PDBx:ls_R_factor_obs>0.1802</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>1.8540</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>30.0000</PDBx:ls_d_res_low>
         <PDBx:ls_number_reflns_R_free>51</PDBx:ls_number_reflns_R_free>
         <PDBx:ls_number_reflns_all>470</PDBx:ls_number_reflns_all>
         <PDBx:ls_number_reflns_obs>470</PDBx:ls_number_reflns_obs>
         <PDBx:ls_percent_reflns_R_free>9.8000</PDBx:ls_percent_reflns_R_free>
         <PDBx:ls_percent_reflns_obs>97.9300</PDBx:ls_percent_reflns_obs>
         <PDBx:ls_wR_factor_R_free>0.2360</PDBx:ls_wR_factor_R_free>
         <PDBx:ls_wR_factor_R_work>0.1900</PDBx:ls_wR_factor_R_work>
         <PDBx:overall_FOM_work_R_set>0.7300</PDBx:overall_FOM_work_R_set>
         <PDBx:overall_SU_B>4.0610</PDBx:overall_SU_B>
         <PDBx:overall_SU_ML>0.1120</PDBx:overall_SU_ML>
         <PDBx:overall_SU_R_Cruickshank_DPI>0.1735</PDBx:overall_SU_R_Cruickshank_DPI>
         <PDBx:overall_SU_R_free>0.1526</PDBx:overall_SU_R_free>
         <PDBx:pdbx_R_Free_selection_details>RANDOM</PDBx:pdbx_R_Free_selection_details>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_ls_cross_valid_method>THROUGHOUT</PDBx:pdbx_ls_cross_valid_method>
         <PDBx:pdbx_ls_sigma_F>0.000</PDBx:pdbx_ls_sigma_F>
         <PDBx:pdbx_method_to_determine_struct>MOLECULAR REPLACEMENT</PDBx:pdbx_method_to_determine_struct>
         <PDBx:pdbx_overall_ESU_R>0.1730</PDBx:pdbx_overall_ESU_R>
         <PDBx:pdbx_overall_ESU_R_Free>0.1530</PDBx:pdbx_overall_ESU_R_Free>
         <PDBx:pdbx_solvent_ion_probe_radii>0.8000</PDBx:pdbx_solvent_ion_probe_radii>
         <PDBx:pdbx_solvent_shrinkage_radii>0.8000</PDBx:pdbx_solvent_shrinkage_radii>
         <PDBx:pdbx_solvent_vdw_probe_radii>1.2000</PDBx:pdbx_solvent_vdw_probe_radii>
         <PDBx:pdbx_starting_model>poly alanine</PDBx:pdbx_starting_model>
         <PDBx:pdbx_stereochemistry_target_values>MAXIMUM LIKELIHOOD</PDBx:pdbx_stereochemistry_target_values>
         <PDBx:solvent_model_details>MASK</PDBx:solvent_model_details>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="LAST" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>1.8540</PDBx:d_res_high>
         <PDBx:d_res_low>30.0000</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>3</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>60</PDBx:number_atoms_total>
         <PDBx:pdbx_number_atoms_ligand>0</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>0</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>57</PDBx:pdbx_number_atoms_protein>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_bond_refined_d">
         <PDBx:dev_ideal>0.005</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>56</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_bond_other_d">
         <PDBx:dev_ideal>0.011</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>63</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_angle_refined_deg">
         <PDBx:dev_ideal>1.123</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>1.965</PDBx:dev_ideal_target>
         <PDBx:number>78</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_angle_other_deg">
         <PDBx:dev_ideal>0.602</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>3.000</PDBx:dev_ideal_target>
         <PDBx:number>141</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_1_deg">
         <PDBx:dev_ideal>8.198</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>5.000</PDBx:dev_ideal_target>
         <PDBx:number>8</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_3_deg">
         <PDBx:dev_ideal>5.082</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>15.000</PDBx:dev_ideal_target>
         <PDBx:number>6</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_chiral_restr">
         <PDBx:dev_ideal>0.049</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>14</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_gen_planes_refined">
         <PDBx:dev_ideal>0.002</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>60</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_gen_planes_other">
         <PDBx:dev_ideal>0.000</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>8</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcbond_it">
         <PDBx:dev_ideal>5.852</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>1.475</PDBx:dev_ideal_target>
         <PDBx:number>35</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcbond_other">
         <PDBx:dev_ideal>5.851</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>1.364</PDBx:dev_ideal_target>
         <PDBx:number>34</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcangle_it">
         <PDBx:dev_ideal>8.406</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>2.046</PDBx:dev_ideal_target>
         <PDBx:number>42</PDBx:number>
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:refine_ls_shellCategory>
      <PDBx:refine_ls_shell d_res_high="1.8540" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2860</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_work>0.2480</PDBx:R_factor_R_work>
         <PDBx:d_res_low>2.0720</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>12</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>125</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>137</PDBx:number_reflns_all>
         <PDBx:pdbx_total_number_of_bins_used>5</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_obs>98.5600</PDBx:percent_reflns_obs>
      </PDBx:refine_ls_shell>
   </PDBx:refine_ls_shellCategory>
   <PDBx:reflnsCategory>
      <PDBx:reflns pdbx_ordinal="1">
         <PDBx:d_resolution_high>1.850</PDBx:d_resolution_high>
         <PDBx:d_resolution_low>100.000</PDBx:d_resolution_low>
         <PDBx:entry_id>4RIK</PDBx:entry_id>
         <PDBx:number_all>521</PDBx:number_all>
         <PDBx:number_obs>521</PDBx:number_obs>
         <PDBx:observed_criterion_sigma_I>-3</PDBx:observed_criterion_sigma_I>
         <PDBx:pdbx_Rmerge_I_obs>0.117</PDBx:pdbx_Rmerge_I_obs>
         <PDBx:pdbx_chi_squared>0.961</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_netI_over_sigmaI>11.100</PDBx:pdbx_netI_over_sigmaI>
         <PDBx:pdbx_redundancy>4.100</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_obs>97.700</PDBx:percent_possible_obs>
      </PDBx:reflns>
   </PDBx:reflnsCategory>
   <PDBx:reflns_shellCategory>
      <PDBx:reflns_shell pdbx_ordinal="1">
         <PDBx:Rmerge_I_obs>0.248</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.850</PDBx:d_res_high>
         <PDBx:d_res_low>1.920</PDBx:d_res_low>
         <PDBx:number_unique_all>43</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.020</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>4.000</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>97.700</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="2">
         <PDBx:Rmerge_I_obs>0.290</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.920</PDBx:d_res_high>
         <PDBx:d_res_low>1.990</PDBx:d_res_low>
         <PDBx:number_unique_all>53</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.073</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>4.200</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>96.400</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="3">
         <PDBx:Rmerge_I_obs>0.261</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.990</PDBx:d_res_high>
         <PDBx:d_res_low>2.080</PDBx:d_res_low>
         <PDBx:number_unique_all>46</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.350</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>4.000</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="4">
         <PDBx:Rmerge_I_obs>0.209</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.080</PDBx:d_res_high>
         <PDBx:d_res_low>2.190</PDBx:d_res_low>
         <PDBx:number_unique_all>57</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.884</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>4.600</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>98.300</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="5">
         <PDBx:Rmerge_I_obs>0.179</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.190</PDBx:d_res_high>
         <PDBx:d_res_low>2.330</PDBx:d_res_low>
         <PDBx:number_unique_all>52</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.293</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>4.200</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="6">
         <PDBx:Rmerge_I_obs>0.202</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.330</PDBx:d_res_high>
         <PDBx:d_res_low>2.510</PDBx:d_res_low>
         <PDBx:number_unique_all>53</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.933</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>4.400</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>89.800</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="7">
         <PDBx:Rmerge_I_obs>0.125</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.510</PDBx:d_res_high>
         <PDBx:d_res_low>2.760</PDBx:d_res_low>
         <PDBx:number_unique_all>40</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.764</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>4.100</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="8">
         <PDBx:Rmerge_I_obs>0.099</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.760</PDBx:d_res_high>
         <PDBx:d_res_low>3.160</PDBx:d_res_low>
         <PDBx:number_unique_all>54</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.805</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>4.000</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="9">
         <PDBx:Rmerge_I_obs>0.083</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>3.160</PDBx:d_res_high>
         <PDBx:d_res_low>3.990</PDBx:d_res_low>
         <PDBx:number_unique_all>57</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.818</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>4.400</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>96.600</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="10">
         <PDBx:Rmerge_I_obs>0.075</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>3.990</PDBx:d_res_high>
         <PDBx:d_res_low>100.000</PDBx:d_res_low>
         <PDBx:number_unique_all>66</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.733</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>3.500</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
   </PDBx:reflns_shellCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>data reduction</PDBx:classification>
         <PDBx:contact_author>Zbyszek Otwinowski</PDBx:contact_author>
         <PDBx:contact_author_email>hkl@hkl-xray.com</PDBx:contact_author_email>
         <PDBx:location>http://www.hkl-xray.com/</PDBx:location>
         <PDBx:name>SCALEPACK</PDBx:name>
         <PDBx:type>program</PDBx:type>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="2">
         <PDBx:classification>molecular replacement</PDBx:classification>
         <PDBx:contact_author>Randy J. Read</PDBx:contact_author>
         <PDBx:contact_author_email>cimr-phaser@lists.cam.ac.uk</PDBx:contact_author_email>
         <PDBx:date>Tue May 20 11:52:06 2014</PDBx:date>
         <PDBx:location>http://www-structmed.cimr.cam.ac.uk/phaser/</PDBx:location>
         <PDBx:name>Phaser</PDBx:name>
         <PDBx:type>program</PDBx:type>
         <PDBx:version>2.5.6</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="3">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:contact_author>Garib N. Murshudov</PDBx:contact_author>
         <PDBx:contact_author_email>garib@ysbl.york.ac.uk</PDBx:contact_author_email>
         <PDBx:language>Fortran_77</PDBx:language>
         <PDBx:location>http://www.ccp4.ac.uk/dist/html/refmac5.html</PDBx:location>
         <PDBx:name>REFMAC</PDBx:name>
         <PDBx:type>program</PDBx:type>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="4">
         <PDBx:classification>data extraction</PDBx:classification>
         <PDBx:contact_author>PDB</PDBx:contact_author>
         <PDBx:contact_author_email>deposit@deposit.rcsb.org</PDBx:contact_author_email>
         <PDBx:date>July. 29, 2014</PDBx:date>
         <PDBx:language>C++</PDBx:language>
         <PDBx:location>http://sw-tools.pdb.org/apps/PDB_EXTRACT/</PDBx:location>
         <PDBx:name>PDB_EXTRACT</PDBx:name>
         <PDBx:type>package</PDBx:type>
         <PDBx:version>3.15</PDBx:version>
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="4RIK">
         <PDBx:pdbx_descriptor>Alpha-synuclein</PDBx:pdbx_descriptor>
         <PDBx:title>Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson&apos;s disease protein alpha-synuclein, residues 69-77</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_biolCategory>
      <PDBx:struct_biol id="1">
         <PDBx:details>The biological unit is a pair of beta-sheets. One sheet is composed of chain A and unit cell translations along the b dimension (for example, x,y+1,z, etc.). The other sheet is composed of the symmetry mate -x+1/2,y+1/2,-z+1, and its unit cell translations along b (for example, -x+1/2,y+3/2,-z+1, etc.).</PDBx:details>
      </PDBx:struct_biol>
   </PDBx:struct_biolCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="4RIK">
         <PDBx:pdbx_keywords>Lipid Binding Protein</PDBx:pdbx_keywords>
         <PDBx:text>Amyloid, alpha-synuclein, Parkinson&apos;s Disease, Toxic Core, NAC, Lipid Binding Protein</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:biol_id xsi:nil="true" />
         <PDBx:db_code>SYUA_HUMAN</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>69</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>P37840</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>AVVTGVTAV</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>69</PDBx:db_align_beg>
         <PDBx:db_align_end>77</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>4RIK</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>69</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>77</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P37840</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>9</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="4RIK">
         <PDBx:space_group_name_H-M>C 1 2 1</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
