Intrahepatic cholestasis

Progressive familial intrahepatic cholestasis (PFIC) is a disorder that causes progressive liver disease, which typically leads to liver failure. In people with PFIC, liver cells are less able to secrete a digestive fluid called bile.

Associated Genes

Gene Name	Chromosome number	BMRB Entries	PDB Entries
AKR1D1	7		PDB Entries
CMC2	16