BMRB Entry 18764
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PDB ID: 4bd3
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR18764
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Title: Phf19 links methylated lysine 36 of histone H3 to regulation of Polycomb activity PubMed: 23104054
Deposition date: 2012-10-04 Original release date: 2012-10-29
Authors: Lapinaite, Audrone; Simon, B.; Carlomagno, T.
Citation: Ballare, Cecilia; Lange, Martin; Lapinaite, Audrone; Martin, Gloria Mas; Morey, Lluis; Pascual, Gloria; Liefke, Robert; Simon, Bernd; Shi, Yang; Gozani, Or; Carlomagno, Teresa; Benitah, Salvador Aznar; Di Croce, Luciano. "Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity." Nat. Struct. Mol. Biol. 19, 1257-1265 (2012).
Assembly members:
PHD_FINGER_PROTEIN_19, polymer, 58 residues, 6714.6566 Da.
HISTONE_H3, polymer, 11 residues, 1258.5055 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: ESCHERICHIA COLI BL21
Entity Sequences (FASTA):
PHD_FINGER_PROTEIN_19: SKLTEGQYVLCRWTDGLYYL
GKIKRVSSSKQSCLVTFEDN
SKYWVLWKDIQHAGVPGE
HISTONE_H3: ATGGVXKPHRY
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 198 |
| 15N chemical shifts | 59 |
| 1H chemical shifts | 447 |
Additional metadata:
Related Database Links:
| UNP | PHF19_HUMAN H31_HUMAN |
| PDB | 2E5Q 4BD3 |
| DBJ | BAG53700 BAI45704 |
| EMBL | CAE45832 |
| GB | AAH22374 AAI08664 AAI25077 AAI25078 ADQ32204 |
| REF | NP_001009936 NP_001179644 NP_001273769 NP_001273772 NP_056466 |
| SP | Q5T6S3 |
| TPG | DAA26446 |
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