BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 19654

Title: NMR Structure of human Mcl-1   PubMed: 24789074

Deposition date: 2013-12-04 Original release date: 2014-05-12

Authors: Liu, Gaohua; Poppe, Leszek; Aoki, Ken; Yamane, Harvey; Lewis, Jeffrey; Szyperski, Thomas

Citation: Liu, Gaohua; Poppe, Leszek; Aoki, Ken; Yamane, Harvey; Lewis, Jeffrey; Szyperski, Thomas. "High-quality NMR Structure of Human Anti-apoptotic Protein Domain Mcl-1(171-327) for Cancer Drug Design"  PLOS 9, e96521-e96521 (2014).

Assembly members:
entity, polymer, 328 residues, 37715.047 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):
entity: MEDELYRQSLEIISRYLREQ ATGAKDTKPMGRSGATSRKA LETLRRVGDGVQRNHETAFQ GMLRKLDIKNEDDVKSLSRV MIHVFSDGVTNWGRIVTLIS FGAFVAKHLKTINQESSIEP LAESITDVLVRTKRDWLVKQ RGWDGFVEFFHVEDLEGGHH HHHHMEDELYRQSLEIISRY LREQATGAKDTKPMGRSGAT SRKALETLRRVGDGVQRNHE TAFQGMLRKLDIKNEDDVKS LSRVMIHVFSDGVTNWGRIV TLISFGAFVAKHLKTINQES SIEPLAESITDVLVRTKRDW LVKQRGWDGFVEFFHVEDLE GGHHHHHH

Data sets:
Data typeCount
13C chemical shifts548
15N chemical shifts175
1H chemical shifts1153

Additional metadata:

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Related Database Links:

PDB 2MHS

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