BMRB Entry 5713
Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR5713
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Title: Influence of pH on NMR structure and stability of the human prion protein globular domain
Deposition date: 2003-03-03 Original release date: 2003-05-21
Authors: Calzolai, Luigi; Zahn, Ralph
Citation: Calzolai, Luigi; Zahn, Ralph. "Influence of pH on NMR structure and stability of the human prion protein globular domain" J. Biol. Chem. ., .-..
Assembly members:
human prion protein, polymer, 112 residues, Formula weight is not available
Natural source: Common Name: HUMAN Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology
Entity Sequences (FASTA):
human prion protein: GSVVGGLGGYMLGSAMSRPI
IHFGSDYEDRYYRENMHRYP
NQVYYRPMDEYSNQNNFVHD
CVNITIKQHTVTTTTKGENF
TETDVKMMERVVEQMCITQY
ERESQAYYQRGS
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 351 |
| 15N chemical shifts | 126 |
| 1H chemical shifts | 763 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | hPrP | 1 |
Entities:
Entity 1, hPrP 112 residues - Formula weight is not available
| 1 | GLY | SER | VAL | VAL | GLY | GLY | LEU | GLY | GLY | TYR | ||||
| 2 | MET | LEU | GLY | SER | ALA | MET | SER | ARG | PRO | ILE | ||||
| 3 | ILE | HIS | PHE | GLY | SER | ASP | TYR | GLU | ASP | ARG | ||||
| 4 | TYR | TYR | ARG | GLU | ASN | MET | HIS | ARG | TYR | PRO | ||||
| 5 | ASN | GLN | VAL | TYR | TYR | ARG | PRO | MET | ASP | GLU | ||||
| 6 | TYR | SER | ASN | GLN | ASN | ASN | PHE | VAL | HIS | ASP | ||||
| 7 | CYS | VAL | ASN | ILE | THR | ILE | LYS | GLN | HIS | THR | ||||
| 8 | VAL | THR | THR | THR | THR | LYS | GLY | GLU | ASN | PHE | ||||
| 9 | THR | GLU | THR | ASP | VAL | LYS | MET | MET | GLU | ARG | ||||
| 10 | VAL | VAL | GLU | GLN | MET | CYS | ILE | THR | GLN | TYR | ||||
| 11 | GLU | ARG | GLU | SER | GLN | ALA | TYR | TYR | GLN | ARG | ||||
| 12 | GLY | SER |
Samples:
sample_1: human prion protein0.8 – 1.3 mM
Ex-cond1: pH: 7.0; temperature: 298 K
Experiments:
| Name | Sample | Sample state | Sample conditions |
|---|---|---|---|
| experiment_1 | sample_1 | not available | Ex-cond1 |
Software:
No software information available
NMR spectrometers:
- unknown unknown 0 MHz
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